Compile Data Set for Download or QSAR

Found 83 hits Enz. Inhib. hit(s) with all data for entry = 50045960   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50088582 (CHEMBL3577346) Show SMILES CCCCn1cc(CCCOc2ccc(cc2OC)C(=O)NCCCCN(CCC)[C@H]2CCc3c(O)cccc3C2)nn1 |r| Show InChI InChI=1S/C34H49N5O4/c1-4-6-21-39-25-28(36-37-39)12-10-22-43-32-17-14-27(24-33(32)42-3)34(41)35-18-7-8-20-38(19-5-2)29-15-16-30-26(23-29)11-9-13-31(30)40/h9,11,13-14,17,24-25,29,40H,4-8,10,12,15-16,18-23H2,1-3H3,(H,35,41)/t29-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.210	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from human dopamine D3 receptor transfected in CHO cells after 1 hr by scintillation counting analysis				J Med Chem 58: 2703-17 (2015) Article DOI: 10.1021/jm501889t BindingDB Entry DOI: 10.7270/Q2R49SHG
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50088582 (CHEMBL3577346) Show SMILES CCCCn1cc(CCCOc2ccc(cc2OC)C(=O)NCCCCN(CCC)[C@H]2CCc3c(O)cccc3C2)nn1 |r| Show InChI InChI=1S/C34H49N5O4/c1-4-6-21-39-25-28(36-37-39)12-10-22-43-32-17-14-27(24-33(32)42-3)34(41)35-18-7-8-20-38(19-5-2)29-15-16-30-26(23-29)11-9-13-31(30)40/h9,11,13-14,17,24-25,29,40H,4-8,10,12,15-16,18-23H2,1-3H3,(H,35,41)/t29-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.470	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from human dopamine D2L receptor transfected in CHO cells after 1 hr by scintillation counting analysis				J Med Chem 58: 2703-17 (2015) Article DOI: 10.1021/jm501889t BindingDB Entry DOI: 10.7270/Q2R49SHG
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50088582 (CHEMBL3577346) Show SMILES CCCCn1cc(CCCOc2ccc(cc2OC)C(=O)NCCCCN(CCC)[C@H]2CCc3c(O)cccc3C2)nn1 |r| Show InChI InChI=1S/C34H49N5O4/c1-4-6-21-39-25-28(36-37-39)12-10-22-43-32-17-14-27(24-33(32)42-3)34(41)35-18-7-8-20-38(19-5-2)29-15-16-30-26(23-29)11-9-13-31(30)40/h9,11,13-14,17,24-25,29,40H,4-8,10,12,15-16,18-23H2,1-3H3,(H,35,41)/t29-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.540	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from human dopamine D2S receptor transfected in CHO cells after 1 hr by scintillation counting analysis				J Med Chem 58: 2703-17 (2015) Article DOI: 10.1021/jm501889t BindingDB Entry DOI: 10.7270/Q2R49SHG
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50088578 (CHEMBL3577342) Show SMILES CCCCn1cc(CCCOc2ccc(cc2OC)C(=O)NCCCCN(CCC)[C@H]2COC(=CC2)C#C)nn1 |r,c:34| Show InChI InChI=1S/C31H45N5O4/c1-5-8-20-36-23-26(33-34-36)12-11-21-39-29-16-13-25(22-30(29)38-4)31(37)32-17-9-10-19-35(18-6-2)27-14-15-28(7-3)40-24-27/h3,13,15-16,22-23,27H,5-6,8-12,14,17-21,24H2,1-2,4H3,(H,32,37)/t27-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.630	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from human dopamine D3 receptor transfected in CHO cells after 1 hr by scintillation counting analysis				J Med Chem 58: 2703-17 (2015) Article DOI: 10.1021/jm501889t BindingDB Entry DOI: 10.7270/Q2R49SHG
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50436541 (CHEMBL2396663) Show SMILES CCCN(CCCCNC(=O)c1ccc(cc1)-c1ccccc1)[C@H]1CCC(=CC1)C#C |r,c:28| Show InChI InChI=1S/C28H34N2O/c1-3-21-30(27-18-12-23(4-2)13-19-27)22-9-8-20-29-28(31)26-16-14-25(15-17-26)24-10-6-5-7-11-24/h2,5-7,10-12,14-17,27H,3,8-9,13,18-22H2,1H3,(H,29,31)/t27-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from human dopamine D3 receptor transfected in CHO cells after 1 hr by scintillation counting analysis				J Med Chem 58: 2703-17 (2015) Article DOI: 10.1021/jm501889t BindingDB Entry DOI: 10.7270/Q2R49SHG
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50088581 (CHEMBL3577345) Show SMILES CCCCn1cc(CCCOc2ccc(cc2OC)C(=O)NCCCCN(CCC)[C@@H]2CCc3c(O)cccc3C2)nn1 |r| Show InChI InChI=1S/C34H49N5O4/c1-4-6-21-39-25-28(36-37-39)12-10-22-43-32-17-14-27(24-33(32)42-3)34(41)35-18-7-8-20-38(19-5-2)29-15-16-30-26(23-29)11-9-13-31(30)40/h9,11,13-14,17,24-25,29,40H,4-8,10,12,15-16,18-23H2,1-3H3,(H,35,41)/t29-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from human dopamine D3 receptor transfected in CHO cells after 1 hr by scintillation counting analysis				J Med Chem 58: 2703-17 (2015) Article DOI: 10.1021/jm501889t BindingDB Entry DOI: 10.7270/Q2R49SHG
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50088578 (CHEMBL3577342) Show SMILES CCCCn1cc(CCCOc2ccc(cc2OC)C(=O)NCCCCN(CCC)[C@H]2COC(=CC2)C#C)nn1 |r,c:34| Show InChI InChI=1S/C31H45N5O4/c1-5-8-20-36-23-26(33-34-36)12-11-21-39-29-16-13-25(22-30(29)38-4)31(37)32-17-9-10-19-35(18-6-2)27-14-15-28(7-3)40-24-27/h3,13,15-16,22-23,27H,5-6,8-12,14,17-21,24H2,1-2,4H3,(H,32,37)/t27-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from human dopamine D2L receptor transfected in CHO cells after 1 hr by scintillation counting analysis				J Med Chem 58: 2703-17 (2015) Article DOI: 10.1021/jm501889t BindingDB Entry DOI: 10.7270/Q2R49SHG
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50088580 (CHEMBL3577344) Show SMILES CCCCn1cc(CCCOc2ccc(cc2OC)C(=O)NCCCCN(CCC)CCc2ccc(O)c3[nH]c(=O)ccc23)nn1 Show InChI InChI=1S/C35H48N6O5/c1-4-6-21-41-25-28(38-39-41)10-9-23-46-31-15-12-27(24-32(31)45-3)35(44)36-18-7-8-20-40(19-5-2)22-17-26-11-14-30(42)34-29(26)13-16-33(43)37-34/h11-16,24-25,42H,4-10,17-23H2,1-3H3,(H,36,44)(H,37,43)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	1.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from human dopamine D3 receptor transfected in CHO cells after 1 hr by scintillation counting analysis				J Med Chem 58: 2703-17 (2015) Article DOI: 10.1021/jm501889t BindingDB Entry DOI: 10.7270/Q2R49SHG
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50088579 (CHEMBL3577343) Show SMILES CCCCn1cc(CCCOc2ccc(cc2OC)C(=O)NCCCCN(CCC)[C@@H]2COC(=CC2)C#C)nn1 |r,c:34| Show InChI InChI=1S/C31H45N5O4/c1-5-8-20-36-23-26(33-34-36)12-11-21-39-29-16-13-25(22-30(29)38-4)31(37)32-17-9-10-19-35(18-6-2)27-14-15-28(7-3)40-24-27/h3,13,15-16,22-23,27H,5-6,8-12,14,17-21,24H2,1-2,4H3,(H,32,37)/t27-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from human dopamine D3 receptor transfected in CHO cells after 1 hr by scintillation counting analysis				J Med Chem 58: 2703-17 (2015) Article DOI: 10.1021/jm501889t BindingDB Entry DOI: 10.7270/Q2R49SHG
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50088578 (CHEMBL3577342) Show SMILES CCCCn1cc(CCCOc2ccc(cc2OC)C(=O)NCCCCN(CCC)[C@H]2COC(=CC2)C#C)nn1 |r,c:34| Show InChI InChI=1S/C31H45N5O4/c1-5-8-20-36-23-26(33-34-36)12-11-21-39-29-16-13-25(22-30(29)38-4)31(37)32-17-9-10-19-35(18-6-2)27-14-15-28(7-3)40-24-27/h3,13,15-16,22-23,27H,5-6,8-12,14,17-21,24H2,1-2,4H3,(H,32,37)/t27-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from human dopamine D2S receptor transfected in CHO cells after 1 hr by scintillation counting analysis				J Med Chem 58: 2703-17 (2015) Article DOI: 10.1021/jm501889t BindingDB Entry DOI: 10.7270/Q2R49SHG
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50436541 (CHEMBL2396663) Show SMILES CCCN(CCCCNC(=O)c1ccc(cc1)-c1ccccc1)[C@H]1CCC(=CC1)C#C |r,c:28| Show InChI InChI=1S/C28H34N2O/c1-3-21-30(27-18-12-23(4-2)13-19-27)22-9-8-20-29-28(31)26-16-14-25(15-17-26)24-10-6-5-7-11-24/h2,5-7,10-12,14-17,27H,3,8-9,13,18-22H2,1H3,(H,29,31)/t27-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from human dopamine D2S receptor transfected in CHO cells after 1 hr by scintillation counting analysis				J Med Chem 58: 2703-17 (2015) Article DOI: 10.1021/jm501889t BindingDB Entry DOI: 10.7270/Q2R49SHG
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50436542 (CHEMBL2397389) Show SMILES CCCN(CCCCNC(=O)c1ccc(cc1)-c1ccccc1)[C@@H]1CCC(=CC1)C#C |r,c:28| Show InChI InChI=1S/C28H34N2O/c1-3-21-30(27-18-12-23(4-2)13-19-27)22-9-8-20-29-28(31)26-16-14-25(15-17-26)24-10-6-5-7-11-24/h2,5-7,10-12,14-17,27H,3,8-9,13,18-22H2,1H3,(H,29,31)/t27-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from human dopamine D3 receptor transfected in CHO cells after 1 hr by scintillation counting analysis				J Med Chem 58: 2703-17 (2015) Article DOI: 10.1021/jm501889t BindingDB Entry DOI: 10.7270/Q2R49SHG
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50088579 (CHEMBL3577343) Show SMILES CCCCn1cc(CCCOc2ccc(cc2OC)C(=O)NCCCCN(CCC)[C@@H]2COC(=CC2)C#C)nn1 |r,c:34| Show InChI InChI=1S/C31H45N5O4/c1-5-8-20-36-23-26(33-34-36)12-11-21-39-29-16-13-25(22-30(29)38-4)31(37)32-17-9-10-19-35(18-6-2)27-14-15-28(7-3)40-24-27/h3,13,15-16,22-23,27H,5-6,8-12,14,17-21,24H2,1-2,4H3,(H,32,37)/t27-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from human dopamine D2L receptor transfected in CHO cells after 1 hr by scintillation counting analysis				J Med Chem 58: 2703-17 (2015) Article DOI: 10.1021/jm501889t BindingDB Entry DOI: 10.7270/Q2R49SHG
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50436542 (CHEMBL2397389) Show SMILES CCCN(CCCCNC(=O)c1ccc(cc1)-c1ccccc1)[C@@H]1CCC(=CC1)C#C |r,c:28| Show InChI InChI=1S/C28H34N2O/c1-3-21-30(27-18-12-23(4-2)13-19-27)22-9-8-20-29-28(31)26-16-14-25(15-17-26)24-10-6-5-7-11-24/h2,5-7,10-12,14-17,27H,3,8-9,13,18-22H2,1H3,(H,29,31)/t27-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from human dopamine D2S receptor transfected in CHO cells after 1 hr by scintillation counting analysis				J Med Chem 58: 2703-17 (2015) Article DOI: 10.1021/jm501889t BindingDB Entry DOI: 10.7270/Q2R49SHG
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50436541 (CHEMBL2396663) Show SMILES CCCN(CCCCNC(=O)c1ccc(cc1)-c1ccccc1)[C@H]1CCC(=CC1)C#C |r,c:28| Show InChI InChI=1S/C28H34N2O/c1-3-21-30(27-18-12-23(4-2)13-19-27)22-9-8-20-29-28(31)26-16-14-25(15-17-26)24-10-6-5-7-11-24/h2,5-7,10-12,14-17,27H,3,8-9,13,18-22H2,1H3,(H,29,31)/t27-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from human dopamine D2L receptor transfected in CHO cells after 1 hr by scintillation counting analysis				J Med Chem 58: 2703-17 (2015) Article DOI: 10.1021/jm501889t BindingDB Entry DOI: 10.7270/Q2R49SHG
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50088579 (CHEMBL3577343) Show SMILES CCCCn1cc(CCCOc2ccc(cc2OC)C(=O)NCCCCN(CCC)[C@@H]2COC(=CC2)C#C)nn1 |r,c:34| Show InChI InChI=1S/C31H45N5O4/c1-5-8-20-36-23-26(33-34-36)12-11-21-39-29-16-13-25(22-30(29)38-4)31(37)32-17-9-10-19-35(18-6-2)27-14-15-28(7-3)40-24-27/h3,13,15-16,22-23,27H,5-6,8-12,14,17-21,24H2,1-2,4H3,(H,32,37)/t27-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from human dopamine D2S receptor transfected in CHO cells after 1 hr by scintillation counting analysis				J Med Chem 58: 2703-17 (2015) Article DOI: 10.1021/jm501889t BindingDB Entry DOI: 10.7270/Q2R49SHG
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50436542 (CHEMBL2397389) Show SMILES CCCN(CCCCNC(=O)c1ccc(cc1)-c1ccccc1)[C@@H]1CCC(=CC1)C#C |r,c:28| Show InChI InChI=1S/C28H34N2O/c1-3-21-30(27-18-12-23(4-2)13-19-27)22-9-8-20-29-28(31)26-16-14-25(15-17-26)24-10-6-5-7-11-24/h2,5-7,10-12,14-17,27H,3,8-9,13,18-22H2,1H3,(H,29,31)/t27-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from human dopamine D2L receptor transfected in CHO cells after 1 hr by scintillation counting analysis				J Med Chem 58: 2703-17 (2015) Article DOI: 10.1021/jm501889t BindingDB Entry DOI: 10.7270/Q2R49SHG
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50018958 (CHEBI:75401 | QUINPIROLE) Show SMILES [H][C@]12CCCN(CCC)[C@]1([H])Cc1c[nH]nc1C2 Show InChI InChI=1S/C13H21N3/c1-2-5-16-6-3-4-10-7-12-11(8-13(10)16)9-14-15-12/h9-10,13H,2-8H2,1H3,(H,14,15)/t10-,13-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from human dopamine D3 receptor transfected in CHO cells after 1 hr by scintillation counting analysis				J Med Chem 58: 2703-17 (2015) Article DOI: 10.1021/jm501889t BindingDB Entry DOI: 10.7270/Q2R49SHG
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50088581 (CHEMBL3577345) Show SMILES CCCCn1cc(CCCOc2ccc(cc2OC)C(=O)NCCCCN(CCC)[C@@H]2CCc3c(O)cccc3C2)nn1 |r| Show InChI InChI=1S/C34H49N5O4/c1-4-6-21-39-25-28(36-37-39)12-10-22-43-32-17-14-27(24-33(32)42-3)34(41)35-18-7-8-20-38(19-5-2)29-15-16-30-26(23-29)11-9-13-31(30)40/h9,11,13-14,17,24-25,29,40H,4-8,10,12,15-16,18-23H2,1-3H3,(H,35,41)/t29-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from human dopamine D2L receptor transfected in CHO cells after 1 hr by scintillation counting analysis				J Med Chem 58: 2703-17 (2015) Article DOI: 10.1021/jm501889t BindingDB Entry DOI: 10.7270/Q2R49SHG
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50088580 (CHEMBL3577344) Show SMILES CCCCn1cc(CCCOc2ccc(cc2OC)C(=O)NCCCCN(CCC)CCc2ccc(O)c3[nH]c(=O)ccc23)nn1 Show InChI InChI=1S/C35H48N6O5/c1-4-6-21-41-25-28(38-39-41)10-9-23-46-31-15-12-27(24-32(31)45-3)35(44)36-18-7-8-20-40(19-5-2)22-17-26-11-14-30(42)34-29(26)13-16-33(43)37-34/h11-16,24-25,42H,4-10,17-23H2,1-3H3,(H,36,44)(H,37,43)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	24	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from human dopamine D2L receptor transfected in CHO cells after 1 hr by scintillation counting analysis				J Med Chem 58: 2703-17 (2015) Article DOI: 10.1021/jm501889t BindingDB Entry DOI: 10.7270/Q2R49SHG
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50088581 (CHEMBL3577345) Show SMILES CCCCn1cc(CCCOc2ccc(cc2OC)C(=O)NCCCCN(CCC)[C@@H]2CCc3c(O)cccc3C2)nn1 |r| Show InChI InChI=1S/C34H49N5O4/c1-4-6-21-39-25-28(36-37-39)12-10-22-43-32-17-14-27(24-33(32)42-3)34(41)35-18-7-8-20-38(19-5-2)29-15-16-30-26(23-29)11-9-13-31(30)40/h9,11,13-14,17,24-25,29,40H,4-8,10,12,15-16,18-23H2,1-3H3,(H,35,41)/t29-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from human dopamine D2S receptor transfected in CHO cells after 1 hr by scintillation counting analysis				J Med Chem 58: 2703-17 (2015) Article DOI: 10.1021/jm501889t BindingDB Entry DOI: 10.7270/Q2R49SHG
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50088580 (CHEMBL3577344) Show SMILES CCCCn1cc(CCCOc2ccc(cc2OC)C(=O)NCCCCN(CCC)CCc2ccc(O)c3[nH]c(=O)ccc23)nn1 Show InChI InChI=1S/C35H48N6O5/c1-4-6-21-41-25-28(38-39-41)10-9-23-46-31-15-12-27(24-32(31)45-3)35(44)36-18-7-8-20-40(19-5-2)22-17-26-11-14-30(42)34-29(26)13-16-33(43)37-34/h11-16,24-25,42H,4-10,17-23H2,1-3H3,(H,36,44)(H,37,43)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	53	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from human dopamine D2S receptor transfected in CHO cells after 1 hr by scintillation counting analysis				J Med Chem 58: 2703-17 (2015) Article DOI: 10.1021/jm501889t BindingDB Entry DOI: 10.7270/Q2R49SHG
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50018958 (CHEBI:75401 | QUINPIROLE) Show SMILES [H][C@]12CCCN(CCC)[C@]1([H])Cc1c[nH]nc1C2 Show InChI InChI=1S/C13H21N3/c1-2-5-16-6-3-4-10-7-12-11(8-13(10)16)9-14-15-12/h9-10,13H,2-8H2,1H3,(H,14,15)/t10-,13-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from human dopamine D2S receptor transfected in CHO cells after 1 hr by scintillation counting analysis				J Med Chem 58: 2703-17 (2015) Article DOI: 10.1021/jm501889t BindingDB Entry DOI: 10.7270/Q2R49SHG
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50018958 (CHEBI:75401 | QUINPIROLE) Show SMILES [H][C@]12CCCN(CCC)[C@]1([H])Cc1c[nH]nc1C2 Show InChI InChI=1S/C13H21N3/c1-2-5-16-6-3-4-10-7-12-11(8-13(10)16)9-14-15-12/h9-10,13H,2-8H2,1H3,(H,14,15)/t10-,13-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	260	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from human dopamine D2L receptor transfected in CHO cells after 1 hr by scintillation counting analysis				J Med Chem 58: 2703-17 (2015) Article DOI: 10.1021/jm501889t BindingDB Entry DOI: 10.7270/Q2R49SHG
					More data for this Ligand-Target Pair
D(1B) dopamine receptor (Homo sapiens (Human))	BDBM50088582 (CHEMBL3577346) Show SMILES CCCCn1cc(CCCOc2ccc(cc2OC)C(=O)NCCCCN(CCC)[C@H]2CCc3c(O)cccc3C2)nn1 |r| Show InChI InChI=1S/C34H49N5O4/c1-4-6-21-39-25-28(36-37-39)12-10-22-43-32-17-14-27(24-33(32)42-3)34(41)35-18-7-8-20-38(19-5-2)29-15-16-30-26(23-29)11-9-13-31(30)40/h9,11,13-14,17,24-25,29,40H,4-8,10,12,15-16,18-23H2,1-3H3,(H,35,41)/t29-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]SCH23390 from human dopamine D5 receptor transfected in HEK293 cells after 1 hr by scintillation counting analysis				J Med Chem 58: 2703-17 (2015) Article DOI: 10.1021/jm501889t BindingDB Entry DOI: 10.7270/Q2R49SHG
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50088582 (CHEMBL3577346) Show SMILES CCCCn1cc(CCCOc2ccc(cc2OC)C(=O)NCCCCN(CCC)[C@H]2CCc3c(O)cccc3C2)nn1 |r| Show InChI InChI=1S/C34H49N5O4/c1-4-6-21-39-25-28(36-37-39)12-10-22-43-32-17-14-27(24-33(32)42-3)34(41)35-18-7-8-20-38(19-5-2)29-15-16-30-26(23-29)11-9-13-31(30)40/h9,11,13-14,17,24-25,29,40H,4-8,10,12,15-16,18-23H2,1-3H3,(H,35,41)/t29-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	710	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]ketanserin from human 5-HT2A receptor transfected in HEK293 cells by scintillation counting analysis				J Med Chem 58: 2703-17 (2015) Article DOI: 10.1021/jm501889t BindingDB Entry DOI: 10.7270/Q2R49SHG
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50088581 (CHEMBL3577345) Show SMILES CCCCn1cc(CCCOc2ccc(cc2OC)C(=O)NCCCCN(CCC)[C@@H]2CCc3c(O)cccc3C2)nn1 |r| Show InChI InChI=1S/C34H49N5O4/c1-4-6-21-39-25-28(36-37-39)12-10-22-43-32-17-14-27(24-33(32)42-3)34(41)35-18-7-8-20-38(19-5-2)29-15-16-30-26(23-29)11-9-13-31(30)40/h9,11,13-14,17,24-25,29,40H,4-8,10,12,15-16,18-23H2,1-3H3,(H,35,41)/t29-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]ketanserin from human 5-HT2A receptor transfected in HEK293 cells by scintillation counting analysis				J Med Chem 58: 2703-17 (2015) Article DOI: 10.1021/jm501889t BindingDB Entry DOI: 10.7270/Q2R49SHG
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM50088578 (CHEMBL3577342) Show SMILES CCCCn1cc(CCCOc2ccc(cc2OC)C(=O)NCCCCN(CCC)[C@H]2COC(=CC2)C#C)nn1 |r,c:34| Show InChI InChI=1S/C31H45N5O4/c1-5-8-20-36-23-26(33-34-36)12-11-21-39-29-16-13-25(22-30(29)38-4)31(37)32-17-9-10-19-35(18-6-2)27-14-15-28(7-3)40-24-27/h3,13,15-16,22-23,27H,5-6,8-12,14,17-21,24H2,1-2,4H3,(H,32,37)/t27-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]SCH23390 from human dopamine D1 receptor transfected in HEK293 cells after 1 hr by scintillation counting analysis				J Med Chem 58: 2703-17 (2015) Article DOI: 10.1021/jm501889t BindingDB Entry DOI: 10.7270/Q2R49SHG
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM50088582 (CHEMBL3577346) Show SMILES CCCCn1cc(CCCOc2ccc(cc2OC)C(=O)NCCCCN(CCC)[C@H]2CCc3c(O)cccc3C2)nn1 |r| Show InChI InChI=1S/C34H49N5O4/c1-4-6-21-39-25-28(36-37-39)12-10-22-43-32-17-14-27(24-33(32)42-3)34(41)35-18-7-8-20-38(19-5-2)29-15-16-30-26(23-29)11-9-13-31(30)40/h9,11,13-14,17,24-25,29,40H,4-8,10,12,15-16,18-23H2,1-3H3,(H,35,41)/t29-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.90E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]SCH23390 from human dopamine D1 receptor transfected in HEK293 cells after 1 hr by scintillation counting analysis				J Med Chem 58: 2703-17 (2015) Article DOI: 10.1021/jm501889t BindingDB Entry DOI: 10.7270/Q2R49SHG
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50088580 (CHEMBL3577344) Show SMILES CCCCn1cc(CCCOc2ccc(cc2OC)C(=O)NCCCCN(CCC)CCc2ccc(O)c3[nH]c(=O)ccc23)nn1 Show InChI InChI=1S/C35H48N6O5/c1-4-6-21-41-25-28(38-39-41)10-9-23-46-31-15-12-27(24-32(31)45-3)35(44)36-18-7-8-20-40(19-5-2)22-17-26-11-14-30(42)34-29(26)13-16-33(43)37-34/h11-16,24-25,42H,4-10,17-23H2,1-3H3,(H,36,44)(H,37,43)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	3.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]ketanserin from human 5-HT2A receptor transfected in HEK293 cells by scintillation counting analysis				J Med Chem 58: 2703-17 (2015) Article DOI: 10.1021/jm501889t BindingDB Entry DOI: 10.7270/Q2R49SHG
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM50088579 (CHEMBL3577343) Show SMILES CCCCn1cc(CCCOc2ccc(cc2OC)C(=O)NCCCCN(CCC)[C@@H]2COC(=CC2)C#C)nn1 |r,c:34| Show InChI InChI=1S/C31H45N5O4/c1-5-8-20-36-23-26(33-34-36)12-11-21-39-29-16-13-25(22-30(29)38-4)31(37)32-17-9-10-19-35(18-6-2)27-14-15-28(7-3)40-24-27/h3,13,15-16,22-23,27H,5-6,8-12,14,17-21,24H2,1-2,4H3,(H,32,37)/t27-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.90E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]SCH23390 from human dopamine D1 receptor transfected in HEK293 cells after 1 hr by scintillation counting analysis				J Med Chem 58: 2703-17 (2015) Article DOI: 10.1021/jm501889t BindingDB Entry DOI: 10.7270/Q2R49SHG
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM50088580 (CHEMBL3577344) Show SMILES CCCCn1cc(CCCOc2ccc(cc2OC)C(=O)NCCCCN(CCC)CCc2ccc(O)c3[nH]c(=O)ccc23)nn1 Show InChI InChI=1S/C35H48N6O5/c1-4-6-21-41-25-28(38-39-41)10-9-23-46-31-15-12-27(24-32(31)45-3)35(44)36-18-7-8-20-40(19-5-2)22-17-26-11-14-30(42)34-29(26)13-16-33(43)37-34/h11-16,24-25,42H,4-10,17-23H2,1-3H3,(H,36,44)(H,37,43)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	4.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]SCH23390 from human dopamine D1 receptor transfected in HEK293 cells after 1 hr by scintillation counting analysis				J Med Chem 58: 2703-17 (2015) Article DOI: 10.1021/jm501889t BindingDB Entry DOI: 10.7270/Q2R49SHG
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50088578 (CHEMBL3577342) Show SMILES CCCCn1cc(CCCOc2ccc(cc2OC)C(=O)NCCCCN(CCC)[C@H]2COC(=CC2)C#C)nn1 |r,c:34| Show InChI InChI=1S/C31H45N5O4/c1-5-8-20-36-23-26(33-34-36)12-11-21-39-29-16-13-25(22-30(29)38-4)31(37)32-17-9-10-19-35(18-6-2)27-14-15-28(7-3)40-24-27/h3,13,15-16,22-23,27H,5-6,8-12,14,17-21,24H2,1-2,4H3,(H,32,37)/t27-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]ketanserin from human 5-HT2A receptor transfected in HEK293 cells by scintillation counting analysis				J Med Chem 58: 2703-17 (2015) Article DOI: 10.1021/jm501889t BindingDB Entry DOI: 10.7270/Q2R49SHG
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM50018958 (CHEBI:75401 | QUINPIROLE) Show SMILES [H][C@]12CCCN(CCC)[C@]1([H])Cc1c[nH]nc1C2 Show InChI InChI=1S/C13H21N3/c1-2-5-16-6-3-4-10-7-12-11(8-13(10)16)9-14-15-12/h9-10,13H,2-8H2,1H3,(H,14,15)/t10-,13-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	8.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]SCH23390 from human dopamine D1 receptor transfected in HEK293 cells after 1 hr by scintillation counting analysis				J Med Chem 58: 2703-17 (2015) Article DOI: 10.1021/jm501889t BindingDB Entry DOI: 10.7270/Q2R49SHG
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50436541 (CHEMBL2396663) Show SMILES CCCN(CCCCNC(=O)c1ccc(cc1)-c1ccccc1)[C@H]1CCC(=CC1)C#C |r,c:28| Show InChI InChI=1S/C28H34N2O/c1-3-21-30(27-18-12-23(4-2)13-19-27)22-9-8-20-29-28(31)26-16-14-25(15-17-26)24-10-6-5-7-11-24/h2,5-7,10-12,14-17,27H,3,8-9,13,18-22H2,1H3,(H,29,31)/t27-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]ketanserin from human 5-HT2A receptor transfected in HEK293 cells by scintillation counting analysis				J Med Chem 58: 2703-17 (2015) Article DOI: 10.1021/jm501889t BindingDB Entry DOI: 10.7270/Q2R49SHG
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM50436541 (CHEMBL2396663) Show SMILES CCCN(CCCCNC(=O)c1ccc(cc1)-c1ccccc1)[C@H]1CCC(=CC1)C#C |r,c:28| Show InChI InChI=1S/C28H34N2O/c1-3-21-30(27-18-12-23(4-2)13-19-27)22-9-8-20-29-28(31)26-16-14-25(15-17-26)24-10-6-5-7-11-24/h2,5-7,10-12,14-17,27H,3,8-9,13,18-22H2,1H3,(H,29,31)/t27-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]SCH23390 from human dopamine D1 receptor transfected in HEK293 cells after 1 hr by scintillation counting analysis				J Med Chem 58: 2703-17 (2015) Article DOI: 10.1021/jm501889t BindingDB Entry DOI: 10.7270/Q2R49SHG
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50088579 (CHEMBL3577343) Show SMILES CCCCn1cc(CCCOc2ccc(cc2OC)C(=O)NCCCCN(CCC)[C@@H]2COC(=CC2)C#C)nn1 |r,c:34| Show InChI InChI=1S/C31H45N5O4/c1-5-8-20-36-23-26(33-34-36)12-11-21-39-29-16-13-25(22-30(29)38-4)31(37)32-17-9-10-19-35(18-6-2)27-14-15-28(7-3)40-24-27/h3,13,15-16,22-23,27H,5-6,8-12,14,17-21,24H2,1-2,4H3,(H,32,37)/t27-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.40E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]ketanserin from human 5-HT2A receptor transfected in HEK293 cells by scintillation counting analysis				J Med Chem 58: 2703-17 (2015) Article DOI: 10.1021/jm501889t BindingDB Entry DOI: 10.7270/Q2R49SHG
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM50436542 (CHEMBL2397389) Show SMILES CCCN(CCCCNC(=O)c1ccc(cc1)-c1ccccc1)[C@@H]1CCC(=CC1)C#C |r,c:28| Show InChI InChI=1S/C28H34N2O/c1-3-21-30(27-18-12-23(4-2)13-19-27)22-9-8-20-29-28(31)26-16-14-25(15-17-26)24-10-6-5-7-11-24/h2,5-7,10-12,14-17,27H,3,8-9,13,18-22H2,1H3,(H,29,31)/t27-/m0/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.80E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]SCH23390 from human dopamine D1 receptor transfected in HEK293 cells after 1 hr by scintillation counting analysis				J Med Chem 58: 2703-17 (2015) Article DOI: 10.1021/jm501889t BindingDB Entry DOI: 10.7270/Q2R49SHG
					More data for this Ligand-Target Pair
D(1B) dopamine receptor (Homo sapiens (Human))	BDBM50088581 (CHEMBL3577345) Show SMILES CCCCn1cc(CCCOc2ccc(cc2OC)C(=O)NCCCCN(CCC)[C@@H]2CCc3c(O)cccc3C2)nn1 |r| Show InChI InChI=1S/C34H49N5O4/c1-4-6-21-39-25-28(36-37-39)12-10-22-43-32-17-14-27(24-33(32)42-3)34(41)35-18-7-8-20-38(19-5-2)29-15-16-30-26(23-29)11-9-13-31(30)40/h9,11,13-14,17,24-25,29,40H,4-8,10,12,15-16,18-23H2,1-3H3,(H,35,41)/t29-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.10E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]SCH23390 from human dopamine D5 receptor transfected in HEK293 cells after 1 hr by scintillation counting analysis				J Med Chem 58: 2703-17 (2015) Article DOI: 10.1021/jm501889t BindingDB Entry DOI: 10.7270/Q2R49SHG
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (Homo sapiens (Human))	BDBM50088581 (CHEMBL3577345) Show SMILES CCCCn1cc(CCCOc2ccc(cc2OC)C(=O)NCCCCN(CCC)[C@@H]2CCc3c(O)cccc3C2)nn1 |r| Show InChI InChI=1S/C34H49N5O4/c1-4-6-21-39-25-28(36-37-39)12-10-22-43-32-17-14-27(24-33(32)42-3)34(41)35-18-7-8-20-38(19-5-2)29-15-16-30-26(23-29)11-9-13-31(30)40/h9,11,13-14,17,24-25,29,40H,4-8,10,12,15-16,18-23H2,1-3H3,(H,35,41)/t29-/m1/s1	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.30E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]SCH23390 from human dopamine D1 receptor transfected in HEK293 cells after 1 hr by scintillation counting analysis				J Med Chem 58: 2703-17 (2015) Article DOI: 10.1021/jm501889t BindingDB Entry DOI: 10.7270/Q2R49SHG
					More data for this Ligand-Target Pair
D(1B) dopamine receptor (Homo sapiens (Human))	BDBM50088578 (CHEMBL3577342) Show SMILES CCCCn1cc(CCCOc2ccc(cc2OC)C(=O)NCCCCN(CCC)[C@H]2COC(=CC2)C#C)nn1 |r,c:34| Show InChI InChI=1S/C31H45N5O4/c1-5-8-20-36-23-26(33-34-36)12-11-21-39-29-16-13-25(22-30(29)38-4)31(37)32-17-9-10-19-35(18-6-2)27-14-15-28(7-3)40-24-27/h3,13,15-16,22-23,27H,5-6,8-12,14,17-21,24H2,1-2,4H3,(H,32,37)/t27-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.40E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]SCH23390 from human dopamine D5 receptor transfected in HEK293 cells after 1 hr by scintillation counting analysis				J Med Chem 58: 2703-17 (2015) Article DOI: 10.1021/jm501889t BindingDB Entry DOI: 10.7270/Q2R49SHG
					More data for this Ligand-Target Pair
D(1B) dopamine receptor (Homo sapiens (Human))	BDBM50088580 (CHEMBL3577344) Show SMILES CCCCn1cc(CCCOc2ccc(cc2OC)C(=O)NCCCCN(CCC)CCc2ccc(O)c3[nH]c(=O)ccc23)nn1 Show InChI InChI=1S/C35H48N6O5/c1-4-6-21-41-25-28(38-39-41)10-9-23-46-31-15-12-27(24-32(31)45-3)35(44)36-18-7-8-20-40(19-5-2)22-17-26-11-14-30(42)34-29(26)13-16-33(43)37-34/h11-16,24-25,42H,4-10,17-23H2,1-3H3,(H,36,44)(H,37,43)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]SCH23390 from human dopamine D5 receptor transfected in HEK293 cells after 1 hr by scintillation counting analysis				J Med Chem 58: 2703-17 (2015) Article DOI: 10.1021/jm501889t BindingDB Entry DOI: 10.7270/Q2R49SHG
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50018958 (CHEBI:75401 | QUINPIROLE) Show SMILES [H][C@]12CCCN(CCC)[C@]1([H])Cc1c[nH]nc1C2 Show InChI InChI=1S/C13H21N3/c1-2-5-16-6-3-4-10-7-12-11(8-13(10)16)9-14-15-12/h9-10,13H,2-8H2,1H3,(H,14,15)/t10-,13-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]ketanserin from human 5-HT2A receptor transfected in HEK293 cells by scintillation counting analysis				J Med Chem 58: 2703-17 (2015) Article DOI: 10.1021/jm501889t BindingDB Entry DOI: 10.7270/Q2R49SHG
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50436542 (CHEMBL2397389) Show SMILES CCCN(CCCCNC(=O)c1ccc(cc1)-c1ccccc1)[C@@H]1CCC(=CC1)C#C |r,c:28| Show InChI InChI=1S/C28H34N2O/c1-3-21-30(27-18-12-23(4-2)13-19-27)22-9-8-20-29-28(31)26-16-14-25(15-17-26)24-10-6-5-7-11-24/h2,5-7,10-12,14-17,27H,3,8-9,13,18-22H2,1H3,(H,29,31)/t27-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.80E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]ketanserin from human 5-HT2A receptor transfected in HEK293 cells by scintillation counting analysis				J Med Chem 58: 2703-17 (2015) Article DOI: 10.1021/jm501889t BindingDB Entry DOI: 10.7270/Q2R49SHG
					More data for this Ligand-Target Pair
D(1B) dopamine receptor (Homo sapiens (Human))	BDBM50088579 (CHEMBL3577343) Show SMILES CCCCn1cc(CCCOc2ccc(cc2OC)C(=O)NCCCCN(CCC)[C@@H]2COC(=CC2)C#C)nn1 |r,c:34| Show InChI InChI=1S/C31H45N5O4/c1-5-8-20-36-23-26(33-34-36)12-11-21-39-29-16-13-25(22-30(29)38-4)31(37)32-17-9-10-19-35(18-6-2)27-14-15-28(7-3)40-24-27/h3,13,15-16,22-23,27H,5-6,8-12,14,17-21,24H2,1-2,4H3,(H,32,37)/t27-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.80E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]SCH23390 from human dopamine D5 receptor transfected in HEK293 cells after 1 hr by scintillation counting analysis				J Med Chem 58: 2703-17 (2015) Article DOI: 10.1021/jm501889t BindingDB Entry DOI: 10.7270/Q2R49SHG
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50018958 (CHEBI:75401 | QUINPIROLE) Show SMILES [H][C@]12CCCN(CCC)[C@]1([H])Cc1c[nH]nc1C2 Show InChI InChI=1S/C13H21N3/c1-2-5-16-6-3-4-10-7-12-11(8-13(10)16)9-14-15-12/h9-10,13H,2-8H2,1H3,(H,14,15)/t10-,13-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Intrinsic activity at human dopamine D2S receptor expressed in HEK293 cells co-transfected with Galphai2 assessed as [35S]GTPgammaS binding after 30 ...				J Med Chem 58: 2703-17 (2015) Article DOI: 10.1021/jm501889t BindingDB Entry DOI: 10.7270/Q2R49SHG
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50436542 (CHEMBL2397389) Show SMILES CCCN(CCCCNC(=O)c1ccc(cc1)-c1ccccc1)[C@@H]1CCC(=CC1)C#C |r,c:28| Show InChI InChI=1S/C28H34N2O/c1-3-21-30(27-18-12-23(4-2)13-19-27)22-9-8-20-29-28(31)26-16-14-25(15-17-26)24-10-6-5-7-11-24/h2,5-7,10-12,14-17,27H,3,8-9,13,18-22H2,1H3,(H,29,31)/t27-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.40E+3	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Intrinsic activity at human dopamine D2S receptor expressed in HEK293 cells co-transfected with Galphai2 assessed as [35S]GTPgammaS binding after 30 ...				J Med Chem 58: 2703-17 (2015) Article DOI: 10.1021/jm501889t BindingDB Entry DOI: 10.7270/Q2R49SHG
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50436541 (CHEMBL2396663) Show SMILES CCCN(CCCCNC(=O)c1ccc(cc1)-c1ccccc1)[C@H]1CCC(=CC1)C#C |r,c:28| Show InChI InChI=1S/C28H34N2O/c1-3-21-30(27-18-12-23(4-2)13-19-27)22-9-8-20-29-28(31)26-16-14-25(15-17-26)24-10-6-5-7-11-24/h2,5-7,10-12,14-17,27H,3,8-9,13,18-22H2,1H3,(H,29,31)/t27-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Intrinsic activity at human dopamine D2S receptor expressed in HEK293 cells co-transfected with Galphai2 assessed as [35S]GTPgammaS binding after 30 ...				J Med Chem 58: 2703-17 (2015) Article DOI: 10.1021/jm501889t BindingDB Entry DOI: 10.7270/Q2R49SHG
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50088578 (CHEMBL3577342) Show SMILES CCCCn1cc(CCCOc2ccc(cc2OC)C(=O)NCCCCN(CCC)[C@H]2COC(=CC2)C#C)nn1 |r,c:34| Show InChI InChI=1S/C31H45N5O4/c1-5-8-20-36-23-26(33-34-36)12-11-21-39-29-16-13-25(22-30(29)38-4)31(37)32-17-9-10-19-35(18-6-2)27-14-15-28(7-3)40-24-27/h3,13,15-16,22-23,27H,5-6,8-12,14,17-21,24H2,1-2,4H3,(H,32,37)/t27-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	660	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Intrinsic activity at human dopamine D2S receptor expressed in HEK293 cells co-transfected with Galphai2 assessed as [35S]GTPgammaS binding after 30 ...				J Med Chem 58: 2703-17 (2015) Article DOI: 10.1021/jm501889t BindingDB Entry DOI: 10.7270/Q2R49SHG
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50088579 (CHEMBL3577343) Show SMILES CCCCn1cc(CCCOc2ccc(cc2OC)C(=O)NCCCCN(CCC)[C@@H]2COC(=CC2)C#C)nn1 |r,c:34| Show InChI InChI=1S/C31H45N5O4/c1-5-8-20-36-23-26(33-34-36)12-11-21-39-29-16-13-25(22-30(29)38-4)31(37)32-17-9-10-19-35(18-6-2)27-14-15-28(7-3)40-24-27/h3,13,15-16,22-23,27H,5-6,8-12,14,17-21,24H2,1-2,4H3,(H,32,37)/t27-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.90E+3	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Intrinsic activity at human dopamine D2S receptor expressed in HEK293 cells co-transfected with Galphai2 assessed as [35S]GTPgammaS binding after 30 ...				J Med Chem 58: 2703-17 (2015) Article DOI: 10.1021/jm501889t BindingDB Entry DOI: 10.7270/Q2R49SHG
					More data for this Ligand-Target Pair

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