Compile Data Set for Download or QSAR

Found 64 hits Enz. Inhib. hit(s) with all data for entry = 50032743   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50334048 ((-)-5-chloro-6-(1H-indol-7-yl)-2,2,4,8-tetramethyl...) Show SMILES CC1CC(C)(C)Nc2c(C)cc(c(Cl)c12)-c1cccc2cc[nH]c12 |w:1.0| Show InChI InChI=1S/C21H23ClN2/c1-12-10-16(15-7-5-6-14-8-9-23-20(14)15)18(22)17-13(2)11-21(3,4)24-19(12)17/h5-10,13,23-24H,11H2,1-4H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of radiolabeled dexamethasone from glucocorticoid receptor expressed in baculovirus				Bioorg Med Chem Lett 21: 168-71 (2010) Article DOI: 10.1016/j.bmcl.2010.11.047 BindingDB Entry DOI: 10.7270/Q2VX0GRB
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50334054 ((+/-)-(3R,4S)-5-chloro-6-(1H-indol-7-yl)-2,2,4,8-t...) Show SMILES C[C@@H]1[C@@H](O)C(C)(C)Nc2c(C)cc(c(Cl)c12)-c1cccc2cc[nH]c12 |r| Show InChI InChI=1S/C21H23ClN2O/c1-11-10-15(14-7-5-6-13-8-9-23-19(13)14)17(22)16-12(2)20(25)21(3,4)24-18(11)16/h5-10,12,20,23-25H,1-4H3/t12-,20+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.900	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of radiolabeled dexamethasone from glucocorticoid receptor expressed in baculovirus				Bioorg Med Chem Lett 21: 168-71 (2010) Article DOI: 10.1016/j.bmcl.2010.11.047 BindingDB Entry DOI: 10.7270/Q2VX0GRB
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50334054 ((+/-)-(3R,4S)-5-chloro-6-(1H-indol-7-yl)-2,2,4,8-t...) Show SMILES C[C@@H]1[C@@H](O)C(C)(C)Nc2c(C)cc(c(Cl)c12)-c1cccc2cc[nH]c12 |r| Show InChI InChI=1S/C21H23ClN2O/c1-11-10-15(14-7-5-6-13-8-9-23-19(13)14)17(22)16-12(2)20(25)21(3,4)24-18(11)16/h5-10,12,20,23-25H,1-4H3/t12-,20+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.900	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of radiolabeled dexamethasone from glucocorticoid receptor expressed in baculovirus				Bioorg Med Chem Lett 21: 168-71 (2010) Article DOI: 10.1016/j.bmcl.2010.11.047 BindingDB Entry DOI: 10.7270/Q2VX0GRB
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50334054 ((+/-)-(3R,4S)-5-chloro-6-(1H-indol-7-yl)-2,2,4,8-t...) Show SMILES C[C@@H]1[C@@H](O)C(C)(C)Nc2c(C)cc(c(Cl)c12)-c1cccc2cc[nH]c12 |r| Show InChI InChI=1S/C21H23ClN2O/c1-11-10-15(14-7-5-6-13-8-9-23-19(13)14)17(22)16-12(2)20(25)21(3,4)24-18(11)16/h5-10,12,20,23-25H,1-4H3/t12-,20+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of radiolabeled dexamethasone from glucocorticoid receptor expressed in baculovirus				Bioorg Med Chem Lett 21: 168-71 (2010) Article DOI: 10.1016/j.bmcl.2010.11.047 BindingDB Entry DOI: 10.7270/Q2VX0GRB
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50334051 (4-allyl-5-chloro-6-(1H-indol-7-yl)-2,2,4,8-tetrame...) Show SMILES Cc1cc(c(Cl)c2c1NC(C)(C)C(=O)C2(C)CC=C)-c1cccc2cc[nH]c12 Show InChI InChI=1S/C24H25ClN2O/c1-6-11-24(5)18-19(25)17(16-9-7-8-15-10-12-26-21(15)16)13-14(2)20(18)27-23(3,4)22(24)28/h6-10,12-13,26-27H,1,11H2,2-5H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of radiolabeled dexamethasone from glucocorticoid receptor expressed in baculovirus				Bioorg Med Chem Lett 21: 168-71 (2010) Article DOI: 10.1016/j.bmcl.2010.11.047 BindingDB Entry DOI: 10.7270/Q2VX0GRB
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50334050 (5-chloro-6-(1H-indol-7-yl)-2,2,4,4,8-pentamethyl-1...) Show SMILES Cc1cc(c(Cl)c2c1NC(C)(C)C(=O)C2(C)C)-c1cccc2cc[nH]c12 Show InChI InChI=1S/C22H23ClN2O/c1-12-11-15(14-8-6-7-13-9-10-24-19(13)14)17(23)16-18(12)25-22(4,5)20(26)21(16,2)3/h6-11,24-25H,1-5H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of radiolabeled dexamethasone from glucocorticoid receptor expressed in baculovirus				Bioorg Med Chem Lett 21: 168-71 (2010) Article DOI: 10.1016/j.bmcl.2010.11.047 BindingDB Entry DOI: 10.7270/Q2VX0GRB
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM19190 ((1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-14-(2-...) Show SMILES [H][C@@]12CC[C@](O)(C(=O)CO)[C@@]1(C)C[C@H](O)[C@@]1([H])[C@@]2([H])CCC2=CC(=O)C=C[C@]12C |r,c:27,t:23| Show InChI InChI=1S/C21H28O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h5,7,9,14-16,18,22,24,26H,3-4,6,8,10-11H2,1-2H3/t14-,15-,16-,18+,19-,20-,21-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	5.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of radiolabeled dexamethasone from glucocorticoid receptor expressed in baculovirus				Bioorg Med Chem Lett 21: 168-71 (2010) Article DOI: 10.1016/j.bmcl.2010.11.047 BindingDB Entry DOI: 10.7270/Q2VX0GRB
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50334049 (5-chloro-6-(1H-indol-7-yl)-2,2,4,8-tetramethyl-1,2...) Show SMILES CC1C(=O)C(C)(C)Nc2c(C)cc(c(Cl)c12)-c1cccc2cc[nH]c12 Show InChI InChI=1S/C21H21ClN2O/c1-11-10-15(14-7-5-6-13-8-9-23-19(13)14)17(22)16-12(2)20(25)21(3,4)24-18(11)16/h5-10,12,23-24H,1-4H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of radiolabeled dexamethasone from glucocorticoid receptor expressed in baculovirus				Bioorg Med Chem Lett 21: 168-71 (2010) Article DOI: 10.1016/j.bmcl.2010.11.047 BindingDB Entry DOI: 10.7270/Q2VX0GRB
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50334052 (5-chloro-6-(1H-indol-7-yl)-2,2,4,8-tetramethyl-4-(...) Show SMILES CC(C)=CCC1(C)C(=O)C(C)(C)Nc2c(C)cc(c(Cl)c12)-c1cccc2cc[nH]c12 |(32.68,-5.02,;31.14,-5.03,;30.36,-3.7,;30.38,-6.37,;28.84,-6.39,;28.08,-7.73,;27.3,-6.39,;29.42,-8.5,;30.75,-7.73,;29.42,-10.04,;30.18,-11.37,;30.9,-9.64,;28.08,-10.81,;26.76,-10.05,;25.43,-10.83,;25.43,-12.37,;24.09,-10.06,;24.09,-8.52,;25.42,-7.75,;25.41,-6.21,;26.75,-8.51,;22.76,-7.75,;22.76,-6.2,;21.42,-5.44,;20.1,-6.21,;20.09,-7.74,;18.94,-8.78,;19.56,-10.19,;21.1,-10.03,;21.43,-8.52,)| Show InChI InChI=1S/C26H29ClN2O/c1-15(2)10-12-26(6)20-21(27)19(18-9-7-8-17-11-13-28-23(17)18)14-16(3)22(20)29-25(4,5)24(26)30/h7-11,13-14,28-29H,12H2,1-6H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of radiolabeled dexamethasone from glucocorticoid receptor expressed in baculovirus				Bioorg Med Chem Lett 21: 168-71 (2010) Article DOI: 10.1016/j.bmcl.2010.11.047 BindingDB Entry DOI: 10.7270/Q2VX0GRB
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50334058 ((3S,4S)-5-chloro-6-(1H-indol-7-yl)-2,2,4,8-tetrame...) Show SMILES C[C@@H]1[C@H](O)C(C)(C)Nc2c(C)cc(c(Cl)c12)-c1cccc2cc[nH]c12 |r| Show InChI InChI=1S/C21H23ClN2O/c1-11-10-15(14-7-5-6-13-8-9-23-19(13)14)17(22)16-12(2)20(25)21(3,4)24-18(11)16/h5-10,12,20,23-25H,1-4H3/t12-,20-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of radiolabeled dexamethasone from glucocorticoid receptor expressed in baculovirus				Bioorg Med Chem Lett 21: 168-71 (2010) Article DOI: 10.1016/j.bmcl.2010.11.047 BindingDB Entry DOI: 10.7270/Q2VX0GRB
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50334048 ((-)-5-chloro-6-(1H-indol-7-yl)-2,2,4,8-tetramethyl...) Show SMILES CC1CC(C)(C)Nc2c(C)cc(c(Cl)c12)-c1cccc2cc[nH]c12 |w:1.0| Show InChI InChI=1S/C21H23ClN2/c1-12-10-16(15-7-5-6-14-8-9-23-20(14)15)18(22)17-13(2)11-21(3,4)24-19(12)17/h5-10,13,23-24H,11H2,1-4H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity to progesterone receptor				Bioorg Med Chem Lett 21: 168-71 (2010) Article DOI: 10.1016/j.bmcl.2010.11.047 BindingDB Entry DOI: 10.7270/Q2VX0GRB
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50334050 (5-chloro-6-(1H-indol-7-yl)-2,2,4,4,8-pentamethyl-1...) Show SMILES Cc1cc(c(Cl)c2c1NC(C)(C)C(=O)C2(C)C)-c1cccc2cc[nH]c12 Show InChI InChI=1S/C22H23ClN2O/c1-12-11-15(14-8-6-7-13-9-10-24-19(13)14)17(23)16-18(12)25-22(4,5)20(26)21(16,2)3/h6-11,24-25H,1-5H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity to progesterone receptor				Bioorg Med Chem Lett 21: 168-71 (2010) Article DOI: 10.1016/j.bmcl.2010.11.047 BindingDB Entry DOI: 10.7270/Q2VX0GRB
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50334055 (5-chloro-6-(1H-indol-7-yl)-2,2,4,4,8-pentamethyl-1...) Show SMILES Cc1cc(c(Cl)c2c1NC(C)(C)C(O)C2(C)C)-c1cccc2cc[nH]c12 Show InChI InChI=1S/C22H25ClN2O/c1-12-11-15(14-8-6-7-13-9-10-24-19(13)14)17(23)16-18(12)25-22(4,5)20(26)21(16,2)3/h6-11,20,24-26H,1-5H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of radiolabeled dexamethasone from glucocorticoid receptor expressed in baculovirus				Bioorg Med Chem Lett 21: 168-71 (2010) Article DOI: 10.1016/j.bmcl.2010.11.047 BindingDB Entry DOI: 10.7270/Q2VX0GRB
					More data for this Ligand-Target Pair
Mineralocorticoid receptor (Homo sapiens (Human))	BDBM50334048 ((-)-5-chloro-6-(1H-indol-7-yl)-2,2,4,8-tetramethyl...) Show SMILES CC1CC(C)(C)Nc2c(C)cc(c(Cl)c12)-c1cccc2cc[nH]c12 |w:1.0| Show InChI InChI=1S/C21H23ClN2/c1-12-10-16(15-7-5-6-14-8-9-23-20(14)15)18(22)17-13(2)11-21(3,4)24-19(12)17/h5-10,13,23-24H,11H2,1-4H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	21	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity to mineralocorticoid receptor				Bioorg Med Chem Lett 21: 168-71 (2010) Article DOI: 10.1016/j.bmcl.2010.11.047 BindingDB Entry DOI: 10.7270/Q2VX0GRB
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50334051 (4-allyl-5-chloro-6-(1H-indol-7-yl)-2,2,4,8-tetrame...) Show SMILES Cc1cc(c(Cl)c2c1NC(C)(C)C(=O)C2(C)CC=C)-c1cccc2cc[nH]c12 Show InChI InChI=1S/C24H25ClN2O/c1-6-11-24(5)18-19(25)17(16-9-7-8-15-10-12-26-21(15)16)13-14(2)20(18)27-23(3,4)22(24)28/h6-10,12-13,26-27H,1,11H2,2-5H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	25	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity to progesterone receptor				Bioorg Med Chem Lett 21: 168-71 (2010) Article DOI: 10.1016/j.bmcl.2010.11.047 BindingDB Entry DOI: 10.7270/Q2VX0GRB
					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50334048 ((-)-5-chloro-6-(1H-indol-7-yl)-2,2,4,8-tetramethyl...) Show SMILES CC1CC(C)(C)Nc2c(C)cc(c(Cl)c12)-c1cccc2cc[nH]c12 |w:1.0| Show InChI InChI=1S/C21H23ClN2/c1-12-10-16(15-7-5-6-14-8-9-23-20(14)15)18(22)17-13(2)11-21(3,4)24-19(12)17/h5-10,13,23-24H,11H2,1-4H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	57	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity to androgen receptor				Bioorg Med Chem Lett 21: 168-71 (2010) Article DOI: 10.1016/j.bmcl.2010.11.047 BindingDB Entry DOI: 10.7270/Q2VX0GRB
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50334049 (5-chloro-6-(1H-indol-7-yl)-2,2,4,8-tetramethyl-1,2...) Show SMILES CC1C(=O)C(C)(C)Nc2c(C)cc(c(Cl)c12)-c1cccc2cc[nH]c12 Show InChI InChI=1S/C21H21ClN2O/c1-11-10-15(14-7-5-6-13-8-9-23-19(13)14)17(22)16-12(2)20(25)21(3,4)24-18(11)16/h5-10,12,23-24H,1-4H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity to progesterone receptor				Bioorg Med Chem Lett 21: 168-71 (2010) Article DOI: 10.1016/j.bmcl.2010.11.047 BindingDB Entry DOI: 10.7270/Q2VX0GRB
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50334053 (4-benzyl-5-chloro-6-(1H-indol-7-yl)-2,2,4,8-tetram...) Show SMILES Cc1cc(c(Cl)c2c1NC(C)(C)C(=O)C2(C)Cc1ccccc1)-c1cccc2cc[nH]c12 Show InChI InChI=1S/C28H27ClN2O/c1-17-15-21(20-12-8-11-19-13-14-30-25(19)20)23(29)22-24(17)31-27(2,3)26(32)28(22,4)16-18-9-6-5-7-10-18/h5-15,30-31H,16H2,1-4H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	270	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity to progesterone receptor				Bioorg Med Chem Lett 21: 168-71 (2010) Article DOI: 10.1016/j.bmcl.2010.11.047 BindingDB Entry DOI: 10.7270/Q2VX0GRB
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50334053 (4-benzyl-5-chloro-6-(1H-indol-7-yl)-2,2,4,8-tetram...) Show SMILES Cc1cc(c(Cl)c2c1NC(C)(C)C(=O)C2(C)Cc1ccccc1)-c1cccc2cc[nH]c12 Show InChI InChI=1S/C28H27ClN2O/c1-17-15-21(20-12-8-11-19-13-14-30-25(19)20)23(29)22-24(17)31-27(2,3)26(32)28(22,4)16-18-9-6-5-7-10-18/h5-15,30-31H,16H2,1-4H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	340	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of radiolabeled dexamethasone from glucocorticoid receptor expressed in baculovirus				Bioorg Med Chem Lett 21: 168-71 (2010) Article DOI: 10.1016/j.bmcl.2010.11.047 BindingDB Entry DOI: 10.7270/Q2VX0GRB
					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50334058 ((3S,4S)-5-chloro-6-(1H-indol-7-yl)-2,2,4,8-tetrame...) Show SMILES C[C@@H]1[C@H](O)C(C)(C)Nc2c(C)cc(c(Cl)c12)-c1cccc2cc[nH]c12 |r| Show InChI InChI=1S/C21H23ClN2O/c1-11-10-15(14-7-5-6-13-8-9-23-19(13)14)17(22)16-12(2)20(25)21(3,4)24-18(11)16/h5-10,12,20,23-25H,1-4H3/t12-,20-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity to androgen receptor				Bioorg Med Chem Lett 21: 168-71 (2010) Article DOI: 10.1016/j.bmcl.2010.11.047 BindingDB Entry DOI: 10.7270/Q2VX0GRB
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50334057 (5-chloro-6-(1H-indol-7-yl)-2,2,3,3,8-pentamethyl-2...) Show SMILES Cc1cc(c(Cl)c2C(=O)C(C)(C)C(C)(C)Nc12)-c1cccc2cc[nH]c12 Show InChI InChI=1S/C22H23ClN2O/c1-12-11-15(14-8-6-7-13-9-10-24-19(13)14)17(23)16-18(12)25-22(4,5)21(2,3)20(16)26/h6-11,24-25H,1-5H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	416	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of radiolabeled dexamethasone from glucocorticoid receptor expressed in baculovirus				Bioorg Med Chem Lett 21: 168-71 (2010) Article DOI: 10.1016/j.bmcl.2010.11.047 BindingDB Entry DOI: 10.7270/Q2VX0GRB
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50334052 (5-chloro-6-(1H-indol-7-yl)-2,2,4,8-tetramethyl-4-(...) Show SMILES CC(C)=CCC1(C)C(=O)C(C)(C)Nc2c(C)cc(c(Cl)c12)-c1cccc2cc[nH]c12 |(32.68,-5.02,;31.14,-5.03,;30.36,-3.7,;30.38,-6.37,;28.84,-6.39,;28.08,-7.73,;27.3,-6.39,;29.42,-8.5,;30.75,-7.73,;29.42,-10.04,;30.18,-11.37,;30.9,-9.64,;28.08,-10.81,;26.76,-10.05,;25.43,-10.83,;25.43,-12.37,;24.09,-10.06,;24.09,-8.52,;25.42,-7.75,;25.41,-6.21,;26.75,-8.51,;22.76,-7.75,;22.76,-6.2,;21.42,-5.44,;20.1,-6.21,;20.09,-7.74,;18.94,-8.78,;19.56,-10.19,;21.1,-10.03,;21.43,-8.52,)| Show InChI InChI=1S/C26H29ClN2O/c1-15(2)10-12-26(6)20-21(27)19(18-9-7-8-17-11-13-28-23(17)18)14-16(3)22(20)29-25(4,5)24(26)30/h7-11,13-14,28-29H,12H2,1-6H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	420	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity to progesterone receptor				Bioorg Med Chem Lett 21: 168-71 (2010) Article DOI: 10.1016/j.bmcl.2010.11.047 BindingDB Entry DOI: 10.7270/Q2VX0GRB
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50334056 (5-chloro-6-(1H-indol-7-yl)-2,2,8-trimethyl-2,3-dih...) Show SMILES Cc1cc(c(Cl)c2C(=O)CC(C)(C)Nc12)-c1cccc2cc[nH]c12 Show InChI InChI=1S/C20H19ClN2O/c1-11-9-14(13-6-4-5-12-7-8-22-19(12)13)17(21)16-15(24)10-20(2,3)23-18(11)16/h4-9,22-23H,10H2,1-3H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	436	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of radiolabeled dexamethasone from glucocorticoid receptor expressed in baculovirus				Bioorg Med Chem Lett 21: 168-71 (2010) Article DOI: 10.1016/j.bmcl.2010.11.047 BindingDB Entry DOI: 10.7270/Q2VX0GRB
					More data for this Ligand-Target Pair
Mineralocorticoid receptor (Homo sapiens (Human))	BDBM50334054 ((+/-)-(3R,4S)-5-chloro-6-(1H-indol-7-yl)-2,2,4,8-t...) Show SMILES C[C@@H]1[C@@H](O)C(C)(C)Nc2c(C)cc(c(Cl)c12)-c1cccc2cc[nH]c12 |r| Show InChI InChI=1S/C21H23ClN2O/c1-11-10-15(14-7-5-6-13-8-9-23-19(13)14)17(22)16-12(2)20(25)21(3,4)24-18(11)16/h5-10,12,20,23-25H,1-4H3/t12-,20+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity to mineralocorticoid receptor				Bioorg Med Chem Lett 21: 168-71 (2010) Article DOI: 10.1016/j.bmcl.2010.11.047 BindingDB Entry DOI: 10.7270/Q2VX0GRB
					More data for this Ligand-Target Pair
Mineralocorticoid receptor (Homo sapiens (Human))	BDBM50334055 (5-chloro-6-(1H-indol-7-yl)-2,2,4,4,8-pentamethyl-1...) Show SMILES Cc1cc(c(Cl)c2c1NC(C)(C)C(O)C2(C)C)-c1cccc2cc[nH]c12 Show InChI InChI=1S/C22H25ClN2O/c1-12-11-15(14-8-6-7-13-9-10-24-19(13)14)17(23)16-18(12)25-22(4,5)20(26)21(16,2)3/h6-11,20,24-26H,1-5H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	890	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity to mineralocorticoid receptor				Bioorg Med Chem Lett 21: 168-71 (2010) Article DOI: 10.1016/j.bmcl.2010.11.047 BindingDB Entry DOI: 10.7270/Q2VX0GRB
					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50334054 ((+/-)-(3R,4S)-5-chloro-6-(1H-indol-7-yl)-2,2,4,8-t...) Show SMILES C[C@@H]1[C@@H](O)C(C)(C)Nc2c(C)cc(c(Cl)c12)-c1cccc2cc[nH]c12 |r| Show InChI InChI=1S/C21H23ClN2O/c1-11-10-15(14-7-5-6-13-8-9-23-19(13)14)17(22)16-12(2)20(25)21(3,4)24-18(11)16/h5-10,12,20,23-25H,1-4H3/t12-,20+/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	900	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity to androgen receptor				Bioorg Med Chem Lett 21: 168-71 (2010) Article DOI: 10.1016/j.bmcl.2010.11.047 BindingDB Entry DOI: 10.7270/Q2VX0GRB
					More data for this Ligand-Target Pair
Androgen receptor (Homo sapiens (Human))	BDBM50334055 (5-chloro-6-(1H-indol-7-yl)-2,2,4,4,8-pentamethyl-1...) Show SMILES Cc1cc(c(Cl)c2c1NC(C)(C)C(O)C2(C)C)-c1cccc2cc[nH]c12 Show InChI InChI=1S/C22H25ClN2O/c1-12-11-15(14-8-6-7-13-9-10-24-19(13)14)17(23)16-18(12)25-22(4,5)20(26)21(16,2)3/h6-11,20,24-26H,1-5H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	915	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity to androgen receptor				Bioorg Med Chem Lett 21: 168-71 (2010) Article DOI: 10.1016/j.bmcl.2010.11.047 BindingDB Entry DOI: 10.7270/Q2VX0GRB
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50334058 ((3S,4S)-5-chloro-6-(1H-indol-7-yl)-2,2,4,8-tetrame...) Show SMILES C[C@@H]1[C@H](O)C(C)(C)Nc2c(C)cc(c(Cl)c12)-c1cccc2cc[nH]c12 |r| Show InChI InChI=1S/C21H23ClN2O/c1-11-10-15(14-7-5-6-13-8-9-23-19(13)14)17(22)16-12(2)20(25)21(3,4)24-18(11)16/h5-10,12,20,23-25H,1-4H3/t12-,20-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity to progesterone receptor				Bioorg Med Chem Lett 21: 168-71 (2010) Article DOI: 10.1016/j.bmcl.2010.11.047 BindingDB Entry DOI: 10.7270/Q2VX0GRB
					More data for this Ligand-Target Pair
Mineralocorticoid receptor (Homo sapiens (Human))	BDBM50334058 ((3S,4S)-5-chloro-6-(1H-indol-7-yl)-2,2,4,8-tetrame...) Show SMILES C[C@@H]1[C@H](O)C(C)(C)Nc2c(C)cc(c(Cl)c12)-c1cccc2cc[nH]c12 |r| Show InChI InChI=1S/C21H23ClN2O/c1-11-10-15(14-7-5-6-13-8-9-23-19(13)14)17(22)16-12(2)20(25)21(3,4)24-18(11)16/h5-10,12,20,23-25H,1-4H3/t12-,20-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity to mineralocorticoid receptor				Bioorg Med Chem Lett 21: 168-71 (2010) Article DOI: 10.1016/j.bmcl.2010.11.047 BindingDB Entry DOI: 10.7270/Q2VX0GRB
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50334054 ((+/-)-(3R,4S)-5-chloro-6-(1H-indol-7-yl)-2,2,4,8-t...) Show SMILES C[C@@H]1[C@@H](O)C(C)(C)Nc2c(C)cc(c(Cl)c12)-c1cccc2cc[nH]c12 |r| Show InChI InChI=1S/C21H23ClN2O/c1-11-10-15(14-7-5-6-13-8-9-23-19(13)14)17(22)16-12(2)20(25)21(3,4)24-18(11)16/h5-10,12,20,23-25H,1-4H3/t12-,20+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity to progesterone receptor				Bioorg Med Chem Lett 21: 168-71 (2010) Article DOI: 10.1016/j.bmcl.2010.11.047 BindingDB Entry DOI: 10.7270/Q2VX0GRB
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50334055 (5-chloro-6-(1H-indol-7-yl)-2,2,4,4,8-pentamethyl-1...) Show SMILES Cc1cc(c(Cl)c2c1NC(C)(C)C(O)C2(C)C)-c1cccc2cc[nH]c12 Show InChI InChI=1S/C22H25ClN2O/c1-12-11-15(14-8-6-7-13-9-10-24-19(13)14)17(23)16-18(12)25-22(4,5)20(26)21(16,2)3/h6-11,20,24-26H,1-5H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity to progesterone receptor				Bioorg Med Chem Lett 21: 168-71 (2010) Article DOI: 10.1016/j.bmcl.2010.11.047 BindingDB Entry DOI: 10.7270/Q2VX0GRB
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50334057 (5-chloro-6-(1H-indol-7-yl)-2,2,3,3,8-pentamethyl-2...) Show SMILES Cc1cc(c(Cl)c2C(=O)C(C)(C)C(C)(C)Nc12)-c1cccc2cc[nH]c12 Show InChI InChI=1S/C22H23ClN2O/c1-12-11-15(14-8-6-7-13-9-10-24-19(13)14)17(23)16-18(12)25-22(4,5)21(2,3)20(16)26/h6-11,24-25H,1-5H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity to progesterone receptor				Bioorg Med Chem Lett 21: 168-71 (2010) Article DOI: 10.1016/j.bmcl.2010.11.047 BindingDB Entry DOI: 10.7270/Q2VX0GRB
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50334054 ((+/-)-(3R,4S)-5-chloro-6-(1H-indol-7-yl)-2,2,4,8-t...) Show SMILES C[C@@H]1[C@@H](O)C(C)(C)Nc2c(C)cc(c(Cl)c12)-c1cccc2cc[nH]c12 |r| Show InChI InChI=1S/C21H23ClN2O/c1-11-10-15(14-7-5-6-13-8-9-23-19(13)14)17(22)16-12(2)20(25)21(3,4)24-18(11)16/h5-10,12,20,23-25H,1-4H3/t12-,20+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity to progesterone receptor				Bioorg Med Chem Lett 21: 168-71 (2010) Article DOI: 10.1016/j.bmcl.2010.11.047 BindingDB Entry DOI: 10.7270/Q2VX0GRB
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50334054 ((+/-)-(3R,4S)-5-chloro-6-(1H-indol-7-yl)-2,2,4,8-t...) Show SMILES C[C@@H]1[C@@H](O)C(C)(C)Nc2c(C)cc(c(Cl)c12)-c1cccc2cc[nH]c12 |r| Show InChI InChI=1S/C21H23ClN2O/c1-11-10-15(14-7-5-6-13-8-9-23-19(13)14)17(22)16-12(2)20(25)21(3,4)24-18(11)16/h5-10,12,20,23-25H,1-4H3/t12-,20+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity to progesterone receptor				Bioorg Med Chem Lett 21: 168-71 (2010) Article DOI: 10.1016/j.bmcl.2010.11.047 BindingDB Entry DOI: 10.7270/Q2VX0GRB
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50334056 (5-chloro-6-(1H-indol-7-yl)-2,2,8-trimethyl-2,3-dih...) Show SMILES Cc1cc(c(Cl)c2C(=O)CC(C)(C)Nc12)-c1cccc2cc[nH]c12 Show InChI InChI=1S/C20H19ClN2O/c1-11-9-14(13-6-4-5-12-7-8-22-19(12)13)17(21)16-15(24)10-20(2,3)23-18(11)16/h4-9,22-23H,10H2,1-3H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity to progesterone receptor				Bioorg Med Chem Lett 21: 168-71 (2010) Article DOI: 10.1016/j.bmcl.2010.11.047 BindingDB Entry DOI: 10.7270/Q2VX0GRB
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50334054 ((+/-)-(3R,4S)-5-chloro-6-(1H-indol-7-yl)-2,2,4,8-t...) Show SMILES C[C@@H]1[C@@H](O)C(C)(C)Nc2c(C)cc(c(Cl)c12)-c1cccc2cc[nH]c12 |r| Show InChI InChI=1S/C21H23ClN2O/c1-11-10-15(14-7-5-6-13-8-9-23-19(13)14)17(22)16-12(2)20(25)21(3,4)24-18(11)16/h5-10,12,20,23-25H,1-4H3/t12-,20+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals Curated by ChEMBL					Assay Description Transrepression activity at glucocorticoid receptor in TNFalpha/IL1beta-stimulated human HepG2 cells assessed as inhibition of NFkappaB-dependent E-s...				Bioorg Med Chem Lett 21: 168-71 (2010) Article DOI: 10.1016/j.bmcl.2010.11.047 BindingDB Entry DOI: 10.7270/Q2VX0GRB
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50334054 ((+/-)-(3R,4S)-5-chloro-6-(1H-indol-7-yl)-2,2,4,8-t...) Show SMILES C[C@@H]1[C@@H](O)C(C)(C)Nc2c(C)cc(c(Cl)c12)-c1cccc2cc[nH]c12 |r| Show InChI InChI=1S/C21H23ClN2O/c1-11-10-15(14-7-5-6-13-8-9-23-19(13)14)17(22)16-12(2)20(25)21(3,4)24-18(11)16/h5-10,12,20,23-25H,1-4H3/t12-,20+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals Curated by ChEMBL					Assay Description Transrepression activity at glucocorticoid receptor in TNFalpha/IL1beta-stimulated human HepG2 cells assessed as inhibition of NFkappaB-dependent E-s...				Bioorg Med Chem Lett 21: 168-71 (2010) Article DOI: 10.1016/j.bmcl.2010.11.047 BindingDB Entry DOI: 10.7270/Q2VX0GRB
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50334054 ((+/-)-(3R,4S)-5-chloro-6-(1H-indol-7-yl)-2,2,4,8-t...) Show SMILES C[C@@H]1[C@@H](O)C(C)(C)Nc2c(C)cc(c(Cl)c12)-c1cccc2cc[nH]c12 |r| Show InChI InChI=1S/C21H23ClN2O/c1-11-10-15(14-7-5-6-13-8-9-23-19(13)14)17(22)16-12(2)20(25)21(3,4)24-18(11)16/h5-10,12,20,23-25H,1-4H3/t12-,20+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals Curated by ChEMBL					Assay Description Transrepression activity at glucocorticoid receptor in IL-1beta-stimulated human HepG2 cells assessed as inhibition of AP1 response element-induced I...				Bioorg Med Chem Lett 21: 168-71 (2010) Article DOI: 10.1016/j.bmcl.2010.11.047 BindingDB Entry DOI: 10.7270/Q2VX0GRB
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50334054 ((+/-)-(3R,4S)-5-chloro-6-(1H-indol-7-yl)-2,2,4,8-t...) Show SMILES C[C@@H]1[C@@H](O)C(C)(C)Nc2c(C)cc(c(Cl)c12)-c1cccc2cc[nH]c12 |r| Show InChI InChI=1S/C21H23ClN2O/c1-11-10-15(14-7-5-6-13-8-9-23-19(13)14)17(22)16-12(2)20(25)21(3,4)24-18(11)16/h5-10,12,20,23-25H,1-4H3/t12-,20+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals Curated by ChEMBL					Assay Description Transrepression activity at glucocorticoid receptor in IL-1beta-stimulated human HepG2 cells assessed as inhibition of AP1 response element-induced I...				Bioorg Med Chem Lett 21: 168-71 (2010) Article DOI: 10.1016/j.bmcl.2010.11.047 BindingDB Entry DOI: 10.7270/Q2VX0GRB
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50334051 (4-allyl-5-chloro-6-(1H-indol-7-yl)-2,2,4,8-tetrame...) Show SMILES Cc1cc(c(Cl)c2c1NC(C)(C)C(=O)C2(C)CC=C)-c1cccc2cc[nH]c12 Show InChI InChI=1S/C24H25ClN2O/c1-6-11-24(5)18-19(25)17(16-9-7-8-15-10-12-26-21(15)16)13-14(2)20(18)27-23(3,4)22(24)28/h6-10,12-13,26-27H,1,11H2,2-5H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.10	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals Curated by ChEMBL					Assay Description Transrepression activity at glucocorticoid receptor in TNFalpha/IL1beta-stimulated human HepG2 cells assessed as inhibition of NFkappaB-dependent E-s...				Bioorg Med Chem Lett 21: 168-71 (2010) Article DOI: 10.1016/j.bmcl.2010.11.047 BindingDB Entry DOI: 10.7270/Q2VX0GRB
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM19190 ((1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-14-(2-...) Show SMILES [H][C@@]12CC[C@](O)(C(=O)CO)[C@@]1(C)C[C@H](O)[C@@]1([H])[C@@]2([H])CCC2=CC(=O)C=C[C@]12C |r,c:27,t:23| Show InChI InChI=1S/C21H28O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h5,7,9,14-16,18,22,24,26H,3-4,6,8,10-11H2,1-2H3/t14-,15-,16-,18+,19-,20-,21-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	n/a	n/a	4.10	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals Curated by ChEMBL					Assay Description Transrepression activity at glucocorticoid receptor in TNFalpha/IL1beta-stimulated human HepG2 cells assessed as inhibition of NFkappaB-dependent E-s...				Bioorg Med Chem Lett 21: 168-71 (2010) Article DOI: 10.1016/j.bmcl.2010.11.047 BindingDB Entry DOI: 10.7270/Q2VX0GRB
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50334050 (5-chloro-6-(1H-indol-7-yl)-2,2,4,4,8-pentamethyl-1...) Show SMILES Cc1cc(c(Cl)c2c1NC(C)(C)C(=O)C2(C)C)-c1cccc2cc[nH]c12 Show InChI InChI=1S/C22H23ClN2O/c1-12-11-15(14-8-6-7-13-9-10-24-19(13)14)17(23)16-18(12)25-22(4,5)20(26)21(16,2)3/h6-11,24-25H,1-5H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.70	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals Curated by ChEMBL					Assay Description Transrepression activity at glucocorticoid receptor in TNFalpha/IL1beta-stimulated human HepG2 cells assessed as inhibition of NFkappaB-dependent E-s...				Bioorg Med Chem Lett 21: 168-71 (2010) Article DOI: 10.1016/j.bmcl.2010.11.047 BindingDB Entry DOI: 10.7270/Q2VX0GRB
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50334048 ((-)-5-chloro-6-(1H-indol-7-yl)-2,2,4,8-tetramethyl...) Show SMILES CC1CC(C)(C)Nc2c(C)cc(c(Cl)c12)-c1cccc2cc[nH]c12 |w:1.0| Show InChI InChI=1S/C21H23ClN2/c1-12-10-16(15-7-5-6-14-8-9-23-20(14)15)18(22)17-13(2)11-21(3,4)24-19(12)17/h5-10,13,23-24H,11H2,1-4H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.40	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals Curated by ChEMBL					Assay Description Transrepression activity at glucocorticoid receptor in TNFalpha/IL1beta-stimulated human HepG2 cells assessed as inhibition of NFkappaB-dependent E-s...				Bioorg Med Chem Lett 21: 168-71 (2010) Article DOI: 10.1016/j.bmcl.2010.11.047 BindingDB Entry DOI: 10.7270/Q2VX0GRB
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50334049 (5-chloro-6-(1H-indol-7-yl)-2,2,4,8-tetramethyl-1,2...) Show SMILES CC1C(=O)C(C)(C)Nc2c(C)cc(c(Cl)c12)-c1cccc2cc[nH]c12 Show InChI InChI=1S/C21H21ClN2O/c1-11-10-15(14-7-5-6-13-8-9-23-19(13)14)17(22)16-12(2)20(25)21(3,4)24-18(11)16/h5-10,12,23-24H,1-4H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals Curated by ChEMBL					Assay Description Transrepression activity at glucocorticoid receptor in TNFalpha/IL1beta-stimulated human HepG2 cells assessed as inhibition of NFkappaB-dependent E-s...				Bioorg Med Chem Lett 21: 168-71 (2010) Article DOI: 10.1016/j.bmcl.2010.11.047 BindingDB Entry DOI: 10.7270/Q2VX0GRB
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50334055 (5-chloro-6-(1H-indol-7-yl)-2,2,4,4,8-pentamethyl-1...) Show SMILES Cc1cc(c(Cl)c2c1NC(C)(C)C(O)C2(C)C)-c1cccc2cc[nH]c12 Show InChI InChI=1S/C22H25ClN2O/c1-12-11-15(14-8-6-7-13-9-10-24-19(13)14)17(23)16-18(12)25-22(4,5)20(26)21(16,2)3/h6-11,20,24-26H,1-5H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals Curated by ChEMBL					Assay Description Transrepression activity at glucocorticoid receptor in TNFalpha/IL1beta-stimulated human HepG2 cells assessed as inhibition of NFkappaB-dependent E-s...				Bioorg Med Chem Lett 21: 168-71 (2010) Article DOI: 10.1016/j.bmcl.2010.11.047 BindingDB Entry DOI: 10.7270/Q2VX0GRB
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50334054 ((+/-)-(3R,4S)-5-chloro-6-(1H-indol-7-yl)-2,2,4,8-t...) Show SMILES C[C@@H]1[C@@H](O)C(C)(C)Nc2c(C)cc(c(Cl)c12)-c1cccc2cc[nH]c12 |r| Show InChI InChI=1S/C21H23ClN2O/c1-11-10-15(14-7-5-6-13-8-9-23-19(13)14)17(22)16-12(2)20(25)21(3,4)24-18(11)16/h5-10,12,20,23-25H,1-4H3/t12-,20+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals Curated by ChEMBL					Assay Description Transrepression activity at glucocorticoid receptor in IL-1beta-stimulated human HepG2 cells assessed as inhibition of AP1 response element-induced I...				Bioorg Med Chem Lett 21: 168-71 (2010) Article DOI: 10.1016/j.bmcl.2010.11.047 BindingDB Entry DOI: 10.7270/Q2VX0GRB
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50334052 (5-chloro-6-(1H-indol-7-yl)-2,2,4,8-tetramethyl-4-(...) Show SMILES CC(C)=CCC1(C)C(=O)C(C)(C)Nc2c(C)cc(c(Cl)c12)-c1cccc2cc[nH]c12 |(32.68,-5.02,;31.14,-5.03,;30.36,-3.7,;30.38,-6.37,;28.84,-6.39,;28.08,-7.73,;27.3,-6.39,;29.42,-8.5,;30.75,-7.73,;29.42,-10.04,;30.18,-11.37,;30.9,-9.64,;28.08,-10.81,;26.76,-10.05,;25.43,-10.83,;25.43,-12.37,;24.09,-10.06,;24.09,-8.52,;25.42,-7.75,;25.41,-6.21,;26.75,-8.51,;22.76,-7.75,;22.76,-6.2,;21.42,-5.44,;20.1,-6.21,;20.09,-7.74,;18.94,-8.78,;19.56,-10.19,;21.1,-10.03,;21.43,-8.52,)| Show InChI InChI=1S/C26H29ClN2O/c1-15(2)10-12-26(6)20-21(27)19(18-9-7-8-17-11-13-28-23(17)18)14-16(3)22(20)29-25(4,5)24(26)30/h7-11,13-14,28-29H,12H2,1-6H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals Curated by ChEMBL					Assay Description Transrepression activity at glucocorticoid receptor in TNFalpha/IL1beta-stimulated human HepG2 cells assessed as inhibition of NFkappaB-dependent E-s...				Bioorg Med Chem Lett 21: 168-71 (2010) Article DOI: 10.1016/j.bmcl.2010.11.047 BindingDB Entry DOI: 10.7270/Q2VX0GRB
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM19190 ((1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-14-(2-...) Show SMILES [H][C@@]12CC[C@](O)(C(=O)CO)[C@@]1(C)C[C@H](O)[C@@]1([H])[C@@]2([H])CCC2=CC(=O)C=C[C@]12C |r,c:27,t:23| Show InChI InChI=1S/C21H28O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h5,7,9,14-16,18,22,24,26H,3-4,6,8,10-11H2,1-2H3/t14-,15-,16-,18+,19-,20-,21-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals Curated by ChEMBL					Assay Description Transrepression activity at glucocorticoid receptor in IL-1beta-stimulated human HepG2 cells assessed as inhibition of AP1 response element-induced I...				Bioorg Med Chem Lett 21: 168-71 (2010) Article DOI: 10.1016/j.bmcl.2010.11.047 BindingDB Entry DOI: 10.7270/Q2VX0GRB
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50334058 ((3S,4S)-5-chloro-6-(1H-indol-7-yl)-2,2,4,8-tetrame...) Show SMILES C[C@@H]1[C@H](O)C(C)(C)Nc2c(C)cc(c(Cl)c12)-c1cccc2cc[nH]c12 |r| Show InChI InChI=1S/C21H23ClN2O/c1-11-10-15(14-7-5-6-13-8-9-23-19(13)14)17(22)16-12(2)20(25)21(3,4)24-18(11)16/h5-10,12,20,23-25H,1-4H3/t12-,20-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals Curated by ChEMBL					Assay Description Transrepression activity at glucocorticoid receptor in TNFalpha/IL1beta-stimulated human HepG2 cells assessed as inhibition of NFkappaB-dependent E-s...				Bioorg Med Chem Lett 21: 168-71 (2010) Article DOI: 10.1016/j.bmcl.2010.11.047 BindingDB Entry DOI: 10.7270/Q2VX0GRB
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50334051 (4-allyl-5-chloro-6-(1H-indol-7-yl)-2,2,4,8-tetrame...) Show SMILES Cc1cc(c(Cl)c2c1NC(C)(C)C(=O)C2(C)CC=C)-c1cccc2cc[nH]c12 Show InChI InChI=1S/C24H25ClN2O/c1-6-11-24(5)18-19(25)17(16-9-7-8-15-10-12-26-21(15)16)13-14(2)20(18)27-23(3,4)22(24)28/h6-10,12-13,26-27H,1,11H2,2-5H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
Ligand Pharmaceuticals Curated by ChEMBL					Assay Description Transrepression activity at glucocorticoid receptor in IL-1beta-stimulated human HepG2 cells assessed as inhibition of AP1 response element-induced I...				Bioorg Med Chem Lett 21: 168-71 (2010) Article DOI: 10.1016/j.bmcl.2010.11.047 BindingDB Entry DOI: 10.7270/Q2VX0GRB
					More data for this Ligand-Target Pair

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