Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
P2Y purinoceptor 14 (Mus musculus) | BDBM50343886 ((R)-4-(4-(2,2,2-trifluoro-1-hydroxyethyl)phenyl)-7...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL | Assay Description Antagonist activity at mouse P2Y14 receptor expressed in HEK293 cells assessed as calcium flux by FLIPR assay | Bioorg Med Chem Lett 21: 2836-9 (2011) Article DOI: 10.1016/j.bmcl.2011.03.081 BindingDB Entry DOI: 10.7270/Q2NP24S4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
P2Y purinoceptor 14 (Mus musculus) | BDBM50343888 ((R)-4-(4-(2,2-difluoro-1-hydroxyethyl)phenyl)-7-(4...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL | Assay Description Antagonist activity at mouse P2Y14 receptor expressed in HEK293 cells assessed as calcium flux by FLIPR assay | Bioorg Med Chem Lett 21: 2836-9 (2011) Article DOI: 10.1016/j.bmcl.2011.03.081 BindingDB Entry DOI: 10.7270/Q2NP24S4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
P2Y purinoceptor 14 (Mus musculus) | BDBM50343885 (4-(4-(2,2,2-trifluoro-1-hydroxyethyl)phenyl)-7-(4-...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL | Assay Description Antagonist activity at mouse P2Y14 receptor expressed in HEK293 cells assessed as calcium flux by FLIPR assay | Bioorg Med Chem Lett 21: 2836-9 (2011) Article DOI: 10.1016/j.bmcl.2011.03.081 BindingDB Entry DOI: 10.7270/Q2NP24S4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
P2Y purinoceptor 14 (Mus musculus) | BDBM50343877 (7-(4-fluoro-2,6-dimethylbenzyloxy)-4-(thiophen-3-y...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL | Assay Description Antagonist activity at mouse P2Y14 receptor expressed in HEK293 cells assessed as calcium flux by FLIPR assay | Bioorg Med Chem Lett 21: 2836-9 (2011) Article DOI: 10.1016/j.bmcl.2011.03.081 BindingDB Entry DOI: 10.7270/Q2NP24S4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
P2Y purinoceptor 14 (Mus musculus) | BDBM50343884 (4-(4-(methylsulfonyl)phenyl)-7-(4-(trifluoromethyl...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL | Assay Description Antagonist activity at mouse P2Y14 receptor expressed in HEK293 cells assessed as calcium flux by FLIPR assay | Bioorg Med Chem Lett 21: 2836-9 (2011) Article DOI: 10.1016/j.bmcl.2011.03.081 BindingDB Entry DOI: 10.7270/Q2NP24S4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
P2Y purinoceptor 14 (Mus musculus) | BDBM50343876 (7-(2,6-dimethylbenzyloxy)-4-(thiophen-3-yl)-2-naph...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 26 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL | Assay Description Antagonist activity at mouse P2Y14 receptor expressed in HEK293 cells assessed as calcium flux by FLIPR assay | Bioorg Med Chem Lett 21: 2836-9 (2011) Article DOI: 10.1016/j.bmcl.2011.03.081 BindingDB Entry DOI: 10.7270/Q2NP24S4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
P2Y purinoceptor 14 (Mus musculus) | BDBM50343887 ((S)-4-(4-(2,2,2-trifluoro-1-hydroxyethyl)phenyl)-7...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 51 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL | Assay Description Antagonist activity at mouse P2Y14 receptor expressed in HEK293 cells assessed as calcium flux by FLIPR assay | Bioorg Med Chem Lett 21: 2836-9 (2011) Article DOI: 10.1016/j.bmcl.2011.03.081 BindingDB Entry DOI: 10.7270/Q2NP24S4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
P2Y purinoceptor 14 (Mus musculus) | BDBM50343878 (4-(thiophen-3-yl)-7-(4-(trifluoromethoxy)phenyl)-2...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 54 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL | Assay Description Antagonist activity at mouse P2Y14 receptor expressed in HEK293 cells assessed as calcium flux by FLIPR assay | Bioorg Med Chem Lett 21: 2836-9 (2011) Article DOI: 10.1016/j.bmcl.2011.03.081 BindingDB Entry DOI: 10.7270/Q2NP24S4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
P2Y purinoceptor 14 (Mus musculus) | BDBM50343872 (7-(2,6-dimethylbenzyloxy)-4-phenyl-2-naphthoic aci...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 110 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL | Assay Description Antagonist activity at mouse P2Y14 receptor expressed in HEK293 cells assessed as calcium flux by FLIPR assay | Bioorg Med Chem Lett 21: 2836-9 (2011) Article DOI: 10.1016/j.bmcl.2011.03.081 BindingDB Entry DOI: 10.7270/Q2NP24S4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
P2Y purinoceptor 14 (Mus musculus) | BDBM50343875 (4-(benzyloxy)-7-(2,6-dimethylbenzyloxy)-2-naphthoi...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 110 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL | Assay Description Antagonist activity at mouse P2Y14 receptor expressed in HEK293 cells assessed as calcium flux by FLIPR assay | Bioorg Med Chem Lett 21: 2836-9 (2011) Article DOI: 10.1016/j.bmcl.2011.03.081 BindingDB Entry DOI: 10.7270/Q2NP24S4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
P2Y purinoceptor 14 (Mus musculus) | BDBM50343871 (7-(2,6-dichlorobenzyloxy)-4-phenyl-2-naphthoic aci...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 190 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL | Assay Description Antagonist activity at mouse P2Y14 receptor expressed in HEK293 cells assessed as calcium flux by FLIPR assay | Bioorg Med Chem Lett 21: 2836-9 (2011) Article DOI: 10.1016/j.bmcl.2011.03.081 BindingDB Entry DOI: 10.7270/Q2NP24S4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
P2Y purinoceptor 14 (Mus musculus) | BDBM50343883 (4-(4-(methylsulfonyl)thiophen-3-yl)-7-(4-(trifluor...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 190 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL | Assay Description Antagonist activity at mouse P2Y14 receptor expressed in HEK293 cells assessed as calcium flux by FLIPR assay | Bioorg Med Chem Lett 21: 2836-9 (2011) Article DOI: 10.1016/j.bmcl.2011.03.081 BindingDB Entry DOI: 10.7270/Q2NP24S4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
P2Y purinoceptor 14 (Mus musculus) | BDBM50343882 (4-(4-(methylsulfonyl)thiophen-3-yl)-7-(4-(trifluor...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 330 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL | Assay Description Antagonist activity at mouse P2Y14 receptor expressed in HEK293 cells assessed as calcium flux by FLIPR assay | Bioorg Med Chem Lett 21: 2836-9 (2011) Article DOI: 10.1016/j.bmcl.2011.03.081 BindingDB Entry DOI: 10.7270/Q2NP24S4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
P2Y purinoceptor 14 (Mus musculus) | BDBM50343881 (4-(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 350 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL | Assay Description Antagonist activity at mouse P2Y14 receptor expressed in HEK293 cells assessed as calcium flux by FLIPR assay | Bioorg Med Chem Lett 21: 2836-9 (2011) Article DOI: 10.1016/j.bmcl.2011.03.081 BindingDB Entry DOI: 10.7270/Q2NP24S4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
P2Y purinoceptor 14 (Mus musculus) | BDBM50343879 (3-fluoro-4-(thiophen-3-yl)-7-(4-(trifluoromethoxy)...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 380 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL | Assay Description Antagonist activity at mouse P2Y14 receptor expressed in HEK293 cells assessed as calcium flux by FLIPR assay | Bioorg Med Chem Lett 21: 2836-9 (2011) Article DOI: 10.1016/j.bmcl.2011.03.081 BindingDB Entry DOI: 10.7270/Q2NP24S4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
P2Y purinoceptor 14 (Mus musculus) | BDBM50343880 (3-hydroxy-4-(thiophen-3-yl)-7-(4-(trifluoromethoxy...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL | Assay Description Antagonist activity at mouse P2Y14 receptor expressed in HEK293 cells assessed as calcium flux by FLIPR assay | Bioorg Med Chem Lett 21: 2836-9 (2011) Article DOI: 10.1016/j.bmcl.2011.03.081 BindingDB Entry DOI: 10.7270/Q2NP24S4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
P2Y purinoceptor 14 (Mus musculus) | BDBM50343873 (7-((2,6-dimethylphenoxy)methyl)-4-phenyl-2-naphtho...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL | Assay Description Antagonist activity at mouse P2Y14 receptor expressed in HEK293 cells assessed as calcium flux by FLIPR assay | Bioorg Med Chem Lett 21: 2836-9 (2011) Article DOI: 10.1016/j.bmcl.2011.03.081 BindingDB Entry DOI: 10.7270/Q2NP24S4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
P2Y purinoceptor 14 (Mus musculus) | BDBM50343868 (7-(benzyloxy)-4-phenyl-2-naphthoic acid | CHEMBL17...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 3.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL | Assay Description Antagonist activity at mouse P2Y14 receptor expressed in HEK293 cells assessed as calcium flux by FLIPR assay | Bioorg Med Chem Lett 21: 2836-9 (2011) Article DOI: 10.1016/j.bmcl.2011.03.081 BindingDB Entry DOI: 10.7270/Q2NP24S4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
P2Y purinoceptor 14 (Mus musculus) | BDBM50343869 (7-phenoxy-4-phenyl-2-naphthoic acid | CHEMBL177488...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 4.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL | Assay Description Antagonist activity at mouse P2Y14 receptor expressed in HEK293 cells assessed as calcium flux by FLIPR assay | Bioorg Med Chem Lett 21: 2836-9 (2011) Article DOI: 10.1016/j.bmcl.2011.03.081 BindingDB Entry DOI: 10.7270/Q2NP24S4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
P2Y purinoceptor 14 (Mus musculus) | BDBM50343874 (7-(2,6-dimethylbenzyloxy)-2-naphthoic acid | CHEMB...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL | Assay Description Antagonist activity at mouse P2Y14 receptor expressed in HEK293 cells assessed as calcium flux by FLIPR assay | Bioorg Med Chem Lett 21: 2836-9 (2011) Article DOI: 10.1016/j.bmcl.2011.03.081 BindingDB Entry DOI: 10.7270/Q2NP24S4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
P2Y purinoceptor 14 (Mus musculus) | BDBM50343870 (7-(4-carboxybenzyloxy)-4-phenyl-2-naphthoic acid |...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL | Assay Description Antagonist activity at mouse P2Y14 receptor expressed in HEK293 cells assessed as calcium flux by FLIPR assay | Bioorg Med Chem Lett 21: 2836-9 (2011) Article DOI: 10.1016/j.bmcl.2011.03.081 BindingDB Entry DOI: 10.7270/Q2NP24S4 | |||||||||||
More data for this Ligand-Target Pair |