Found 141 hits Enz. Inhib. hit(s) with all data for entry = 50033646 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50306682
((R)-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)-5-(1...)Show SMILES C[C@@H](Oc1cc(cnc1N)-c1cnn(c1)C1CCNCC1)c1c(Cl)ccc(F)c1Cl |r| Show InChI InChI=1S/C21H22Cl2FN5O/c1-12(19-16(22)2-3-17(24)20(19)23)30-18-8-13(9-27-21(18)25)14-10-28-29(11-14)15-4-6-26-7-5-15/h2-3,8-12,15,26H,4-7H2,1H3,(H2,25,27)/t12-/m1/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem
Patents
Similars
| PDB Article PubMed
| n/a | n/a | 0.780 | n/a | n/a | n/a | n/a | n/a | n/a |
St. Jude Children's Research Hospital
Curated by ChEMBL
| Assay Description Inhibition of recombinant MET using biotinylated-poly(GT) peptide as substrate after 60 mins |
Bioorg Med Chem Lett 21: 4592-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.05.103 BindingDB Entry DOI: 10.7270/Q2N87B4V |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
ALK tyrosine kinase receptor
(Homo sapiens (Human)) | BDBM50306682
((R)-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)-5-(1...)Show SMILES C[C@@H](Oc1cc(cnc1N)-c1cnn(c1)C1CCNCC1)c1c(Cl)ccc(F)c1Cl |r| Show InChI InChI=1S/C21H22Cl2FN5O/c1-12(19-16(22)2-3-17(24)20(19)23)30-18-8-13(9-27-21(18)25)14-10-28-29(11-14)15-4-6-26-7-5-15/h2-3,8-12,15,26H,4-7H2,1H3,(H2,25,27)/t12-/m1/s1 | PDB
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UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem
Patents
Similars
| PDB Article PubMed
| n/a | n/a | 600 | n/a | n/a | n/a | n/a | n/a | n/a |
St. Jude Children's Research Hospital
Curated by ChEMBL
| Assay Description Inhibition of 6xHis-tagged NPM-ALK using biotinylated-poly(GT) peptide as substrate after 60 mins |
Bioorg Med Chem Lett 21: 4592-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.05.103 BindingDB Entry DOI: 10.7270/Q2N87B4V |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Insulin receptor
(Homo sapiens (Human)) | BDBM50306682
((R)-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)-5-(1...)Show SMILES C[C@@H](Oc1cc(cnc1N)-c1cnn(c1)C1CCNCC1)c1c(Cl)ccc(F)c1Cl |r| Show InChI InChI=1S/C21H22Cl2FN5O/c1-12(19-16(22)2-3-17(24)20(19)23)30-18-8-13(9-27-21(18)25)14-10-28-29(11-14)15-4-6-26-7-5-15/h2-3,8-12,15,26H,4-7H2,1H3,(H2,25,27)/t12-/m1/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 650 | n/a | n/a | n/a | n/a | n/a | n/a |
St. Jude Children's Research Hospital
Curated by ChEMBL
| Assay Description Inhibition of recombinant IRK using biotinylated-poly(GT) peptide as substrate after 60 mins |
Bioorg Med Chem Lett 21: 4592-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.05.103 BindingDB Entry DOI: 10.7270/Q2N87B4V |
More data for this Ligand-Target Pair | |
ALK tyrosine kinase receptor
(Homo sapiens (Human)) | BDBM50348945
(CHEMBL1807757)Show SMILES COC(=O)c1cccc(Oc2nc[nH]c(=O)c2C=CC(C)=O)c1 |w:17.17| Show InChI InChI=1S/C16H14N2O5/c1-10(19)6-7-13-14(20)17-9-18-15(13)23-12-5-3-4-11(8-12)16(21)22-2/h3-9H,1-2H3,(H,17,18,20) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 3.03E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
St. Jude Children's Research Hospital
Curated by ChEMBL
| Assay Description Inhibition of 6xHis-tagged NPM-ALK using biotinylated-poly(GT) peptide as substrate after 60 mins |
Bioorg Med Chem Lett 21: 4592-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.05.103 BindingDB Entry DOI: 10.7270/Q2N87B4V |
More data for this Ligand-Target Pair | |
Hepatocyte growth factor receptor
(Homo sapiens (Human)) | BDBM50348945
(CHEMBL1807757)Show SMILES COC(=O)c1cccc(Oc2nc[nH]c(=O)c2C=CC(C)=O)c1 |w:17.17| Show InChI InChI=1S/C16H14N2O5/c1-10(19)6-7-13-14(20)17-9-18-15(13)23-12-5-3-4-11(8-12)16(21)22-2/h3-9H,1-2H3,(H,17,18,20) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 4.01E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
St. Jude Children's Research Hospital
Curated by ChEMBL
| Assay Description Inhibition of recombinant MET using biotinylated-poly(GT) peptide as substrate after 60 mins |
Bioorg Med Chem Lett 21: 4592-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.05.103 BindingDB Entry DOI: 10.7270/Q2N87B4V |
More data for this Ligand-Target Pair | |
ALK tyrosine kinase receptor
(Homo sapiens (Human)) | BDBM50348957
(CHEMBL1808094)Show SMILES CC(=O)C=Cc1c(Oc2cccc(c2)C(C)=O)nc[nH]c1=O |w:4.4| Show InChI InChI=1S/C16H14N2O4/c1-10(19)6-7-14-15(21)17-9-18-16(14)22-13-5-3-4-12(8-13)11(2)20/h3-9H,1-2H3,(H,17,18,21) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 6.25E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
St. Jude Children's Research Hospital
Curated by ChEMBL
| Assay Description Inhibition of 6xHis-tagged NPM-ALK using biotinylated-poly(GT) peptide as substrate after 60 mins |
Bioorg Med Chem Lett 21: 4592-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.05.103 BindingDB Entry DOI: 10.7270/Q2N87B4V |
More data for this Ligand-Target Pair | |
ALK tyrosine kinase receptor
(Homo sapiens (Human)) | BDBM50348956
(CHEMBL1808093)Show SMILES CC(=O)Nc1ccc(Oc2nc[nH]c(=O)c2C=CC(C)=O)cc1 |w:16.16| Show InChI InChI=1S/C16H15N3O4/c1-10(20)3-8-14-15(22)17-9-18-16(14)23-13-6-4-12(5-7-13)19-11(2)21/h3-9H,1-2H3,(H,19,21)(H,17,18,22) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 6.64E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
St. Jude Children's Research Hospital
Curated by ChEMBL
| Assay Description Inhibition of 6xHis-tagged NPM-ALK using biotinylated-poly(GT) peptide as substrate after 60 mins |
Bioorg Med Chem Lett 21: 4592-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.05.103 BindingDB Entry DOI: 10.7270/Q2N87B4V |
More data for this Ligand-Target Pair | |
ALK tyrosine kinase receptor
(Homo sapiens (Human)) | BDBM50348959
(CHEMBL1808096)Show SMILES CC(=O)C=Cc1c(Oc2ccc(cc2)C#N)nc[nH]c1=O |w:4.4| Show InChI InChI=1S/C15H11N3O3/c1-10(19)2-7-13-14(20)17-9-18-15(13)21-12-5-3-11(8-16)4-6-12/h2-7,9H,1H3,(H,17,18,20) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 6.91E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
St. Jude Children's Research Hospital
Curated by ChEMBL
| Assay Description Inhibition of 6xHis-tagged NPM-ALK using biotinylated-poly(GT) peptide as substrate after 60 mins |
Bioorg Med Chem Lett 21: 4592-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.05.103 BindingDB Entry DOI: 10.7270/Q2N87B4V |
More data for this Ligand-Target Pair | |
ALK tyrosine kinase receptor
(Homo sapiens (Human)) | BDBM50348965
(CHEMBL1808102)Show SMILES CCOC(=O)c1ccccc1Oc1nc[nH]c(=O)c1C=CC(C)=O |w:19.20| Show InChI InChI=1S/C17H16N2O5/c1-3-23-17(22)12-6-4-5-7-14(12)24-16-13(9-8-11(2)20)15(21)18-10-19-16/h4-10H,3H2,1-2H3,(H,18,19,21) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 7.54E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
St. Jude Children's Research Hospital
Curated by ChEMBL
| Assay Description Inhibition of 6xHis-tagged NPM-ALK using biotinylated-poly(GT) peptide as substrate after 60 mins |
Bioorg Med Chem Lett 21: 4592-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.05.103 BindingDB Entry DOI: 10.7270/Q2N87B4V |
More data for this Ligand-Target Pair | |
ALK tyrosine kinase receptor
(Homo sapiens (Human)) | BDBM50348960
(CHEMBL1808097)Show SMILES COc1cc(Oc2nc[nH]c(=O)c2C=CC(C)=O)c(cc1OC)C(C)=O |w:13.13| Show InChI InChI=1S/C18H18N2O6/c1-10(21)5-6-12-17(23)19-9-20-18(12)26-14-8-16(25-4)15(24-3)7-13(14)11(2)22/h5-9H,1-4H3,(H,19,20,23) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 7.54E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
St. Jude Children's Research Hospital
Curated by ChEMBL
| Assay Description Inhibition of 6xHis-tagged NPM-ALK using biotinylated-poly(GT) peptide as substrate after 60 mins |
Bioorg Med Chem Lett 21: 4592-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.05.103 BindingDB Entry DOI: 10.7270/Q2N87B4V |
More data for this Ligand-Target Pair | |
ALK tyrosine kinase receptor
(Homo sapiens (Human)) | BDBM50348958
(CHEMBL1808095)Show SMILES CC(=O)C=Cc1c(Oc2ccc(O)cc2)nc[nH]c1=O |w:4.4| Show InChI InChI=1S/C14H12N2O4/c1-9(17)2-7-12-13(19)15-8-16-14(12)20-11-5-3-10(18)4-6-11/h2-8,18H,1H3,(H,15,16,19) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 7.57E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
St. Jude Children's Research Hospital
Curated by ChEMBL
| Assay Description Inhibition of 6xHis-tagged NPM-ALK using biotinylated-poly(GT) peptide as substrate after 60 mins |
Bioorg Med Chem Lett 21: 4592-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.05.103 BindingDB Entry DOI: 10.7270/Q2N87B4V |
More data for this Ligand-Target Pair | |
ALK tyrosine kinase receptor
(Homo sapiens (Human)) | BDBM50348971
(CHEMBL1806514)Show SMILES COC(=O)c1cccc(Oc2nc[nH]c(=O)c2C2CC(C)=NN2C(C)=O)c1 |c:21| Show InChI InChI=1S/C18H18N4O5/c1-10-7-14(22(21-10)11(2)23)15-16(24)19-9-20-17(15)27-13-6-4-5-12(8-13)18(25)26-3/h4-6,8-9,14H,7H2,1-3H3,(H,19,20,24) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 9.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
St. Jude Children's Research Hospital
Curated by ChEMBL
| Assay Description Inhibition of 6xHis-tagged NPM-ALK using biotinylated-poly(GT) peptide as substrate after 60 mins |
Bioorg Med Chem Lett 21: 4592-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.05.103 BindingDB Entry DOI: 10.7270/Q2N87B4V |
More data for this Ligand-Target Pair | |
ALK tyrosine kinase receptor
(Homo sapiens (Human)) | BDBM50348969
(CHEMBL1808107)Show SMILES CC(=O)C=Cc1c(Oc2cc(ccc2Cl)C(F)(F)F)nc[nH]c1=O |w:4.4| Show InChI InChI=1S/C15H10ClF3N2O3/c1-8(22)2-4-10-13(23)20-7-21-14(10)24-12-6-9(15(17,18)19)3-5-11(12)16/h2-7H,1H3,(H,20,21,23) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 9.87E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
St. Jude Children's Research Hospital
Curated by ChEMBL
| Assay Description Inhibition of 6xHis-tagged NPM-ALK using biotinylated-poly(GT) peptide as substrate after 60 mins |
Bioorg Med Chem Lett 21: 4592-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.05.103 BindingDB Entry DOI: 10.7270/Q2N87B4V |
More data for this Ligand-Target Pair | |
ALK tyrosine kinase receptor
(Homo sapiens (Human)) | BDBM50348963
(CHEMBL1808100)Show SMILES COC(=O)c1ccc(OC)cc1Oc1nc[nH]c(=O)c1C=CC(C)=O |w:20.21| Show InChI InChI=1S/C17H16N2O6/c1-10(20)4-6-13-15(21)18-9-19-16(13)25-14-8-11(23-2)5-7-12(14)17(22)24-3/h4-9H,1-3H3,(H,18,19,21) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.02E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
St. Jude Children's Research Hospital
Curated by ChEMBL
| Assay Description Inhibition of 6xHis-tagged NPM-ALK using biotinylated-poly(GT) peptide as substrate after 60 mins |
Bioorg Med Chem Lett 21: 4592-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.05.103 BindingDB Entry DOI: 10.7270/Q2N87B4V |
More data for this Ligand-Target Pair | |
Insulin receptor
(Homo sapiens (Human)) | BDBM50348955
(CHEMBL1808090)Show SMILES CCOC(=O)C=Cc1c(Oc2cccc(OC)c2)nc[nH]c1=O |w:6.6| Show InChI InChI=1S/C16H16N2O5/c1-3-22-14(19)8-7-13-15(20)17-10-18-16(13)23-12-6-4-5-11(9-12)21-2/h4-10H,3H2,1-2H3,(H,17,18,20) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >4.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
St. Jude Children's Research Hospital
Curated by ChEMBL
| Assay Description Inhibition of recombinant IRK using biotinylated-poly(GT) peptide as substrate after 60 mins |
Bioorg Med Chem Lett 21: 4592-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.05.103 BindingDB Entry DOI: 10.7270/Q2N87B4V |
More data for this Ligand-Target Pair | |
Insulin receptor
(Homo sapiens (Human)) | BDBM50348954
(CHEMBL1808089)Show SMILES COc1cccc(Oc2nc[nH]c(=O)c2C=CC(C)=O)c1 |w:15.15| Show InChI InChI=1S/C15H14N2O4/c1-10(18)6-7-13-14(19)16-9-17-15(13)21-12-5-3-4-11(8-12)20-2/h3-9H,1-2H3,(H,16,17,19) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >4.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
St. Jude Children's Research Hospital
Curated by ChEMBL
| Assay Description Inhibition of recombinant IRK using biotinylated-poly(GT) peptide as substrate after 60 mins |
Bioorg Med Chem Lett 21: 4592-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.05.103 BindingDB Entry DOI: 10.7270/Q2N87B4V |
More data for this Ligand-Target Pair | |
Insulin receptor
(Homo sapiens (Human)) | BDBM50348951
(CHEMBL1807772)Show SMILES CCOC(=O)C=Cc1c(Oc2cccc(c2)C#N)nc[nH]c1=O |w:6.6| Show InChI InChI=1S/C16H13N3O4/c1-2-22-14(20)7-6-13-15(21)18-10-19-16(13)23-12-5-3-4-11(8-12)9-17/h3-8,10H,2H2,1H3,(H,18,19,21) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >4.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
St. Jude Children's Research Hospital
Curated by ChEMBL
| Assay Description Inhibition of recombinant IRK using biotinylated-poly(GT) peptide as substrate after 60 mins |
Bioorg Med Chem Lett 21: 4592-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.05.103 BindingDB Entry DOI: 10.7270/Q2N87B4V |
More data for this Ligand-Target Pair | |
Insulin receptor
(Homo sapiens (Human)) | BDBM50348957
(CHEMBL1808094)Show SMILES CC(=O)C=Cc1c(Oc2cccc(c2)C(C)=O)nc[nH]c1=O |w:4.4| Show InChI InChI=1S/C16H14N2O4/c1-10(19)6-7-14-15(21)17-9-18-16(14)22-13-5-3-4-12(8-13)11(2)20/h3-9H,1-2H3,(H,17,18,21) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >4.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
St. Jude Children's Research Hospital
Curated by ChEMBL
| Assay Description Inhibition of recombinant IRK using biotinylated-poly(GT) peptide as substrate after 60 mins |
Bioorg Med Chem Lett 21: 4592-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.05.103 BindingDB Entry DOI: 10.7270/Q2N87B4V |
More data for this Ligand-Target Pair | |
Insulin receptor
(Homo sapiens (Human)) | BDBM50348956
(CHEMBL1808093)Show SMILES CC(=O)Nc1ccc(Oc2nc[nH]c(=O)c2C=CC(C)=O)cc1 |w:16.16| Show InChI InChI=1S/C16H15N3O4/c1-10(20)3-8-14-15(22)17-9-18-16(14)23-13-6-4-12(5-7-13)19-11(2)21/h3-9H,1-2H3,(H,19,21)(H,17,18,22) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >4.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
St. Jude Children's Research Hospital
Curated by ChEMBL
| Assay Description Inhibition of recombinant IRK using biotinylated-poly(GT) peptide as substrate after 60 mins |
Bioorg Med Chem Lett 21: 4592-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.05.103 BindingDB Entry DOI: 10.7270/Q2N87B4V |
More data for this Ligand-Target Pair | |
Insulin receptor
(Homo sapiens (Human)) | BDBM50348980
(CHEMBL1808092)Show SMILES CCOC(=O)C=Cc1c(Oc2c(Cl)cccc2Cl)nc[nH]c1=O |w:6.6| Show InChI InChI=1S/C15H12Cl2N2O4/c1-2-22-12(20)7-6-9-14(21)18-8-19-15(9)23-13-10(16)4-3-5-11(13)17/h3-8H,2H2,1H3,(H,18,19,21) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >4.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
St. Jude Children's Research Hospital
Curated by ChEMBL
| Assay Description Inhibition of recombinant IRK using biotinylated-poly(GT) peptide as substrate after 60 mins |
Bioorg Med Chem Lett 21: 4592-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.05.103 BindingDB Entry DOI: 10.7270/Q2N87B4V |
More data for this Ligand-Target Pair | |
Insulin receptor
(Homo sapiens (Human)) | BDBM50348979
(CHEMBL1808091)Show SMILES CC(=O)C=Cc1c(Oc2c(Cl)cccc2Cl)nc[nH]c1=O |w:4.4| Show InChI InChI=1S/C14H10Cl2N2O3/c1-8(19)5-6-9-13(20)17-7-18-14(9)21-12-10(15)3-2-4-11(12)16/h2-7H,1H3,(H,17,18,20) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >4.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
St. Jude Children's Research Hospital
Curated by ChEMBL
| Assay Description Inhibition of recombinant IRK using biotinylated-poly(GT) peptide as substrate after 60 mins |
Bioorg Med Chem Lett 21: 4592-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.05.103 BindingDB Entry DOI: 10.7270/Q2N87B4V |
More data for this Ligand-Target Pair | |
ALK tyrosine kinase receptor
(Homo sapiens (Human)) | BDBM50348973
(CHEMBL1808222)Show InChI InChI=1S/C17H13N3O4/c1-23-17(22)12-3-2-4-13(9-12)24-16-14(15(21)19-10-20-16)11-5-7-18-8-6-11/h2-10H,1H3,(H,19,20,21) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >4.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
St. Jude Children's Research Hospital
Curated by ChEMBL
| Assay Description Inhibition of 6xHis-tagged NPM-ALK using biotinylated-poly(GT) peptide as substrate after 60 mins |
Bioorg Med Chem Lett 21: 4592-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.05.103 BindingDB Entry DOI: 10.7270/Q2N87B4V |
More data for this Ligand-Target Pair | |
ALK tyrosine kinase receptor
(Homo sapiens (Human)) | BDBM50348972
(CHEMBL1808221)Show SMILES COC(=O)c1cccc(Oc2nc[nH]c(=O)c2C2CC(C)N=N2)c1 |c:22| Show InChI InChI=1S/C16H16N4O4/c1-9-6-12(20-19-9)13-14(21)17-8-18-15(13)24-11-5-3-4-10(7-11)16(22)23-2/h3-5,7-9,12H,6H2,1-2H3,(H,17,18,21) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >4.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
St. Jude Children's Research Hospital
Curated by ChEMBL
| Assay Description Inhibition of 6xHis-tagged NPM-ALK using biotinylated-poly(GT) peptide as substrate after 60 mins |
Bioorg Med Chem Lett 21: 4592-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.05.103 BindingDB Entry DOI: 10.7270/Q2N87B4V |
More data for this Ligand-Target Pair | |
ALK tyrosine kinase receptor
(Homo sapiens (Human)) | BDBM50348982
(CHEMBL1808220)Show SMILES COC(=O)c1cccc(Oc2nc[nH]c(=O)c2C2CC(C)=NN2C)c1 |c:21| Show InChI InChI=1S/C17H18N4O4/c1-10-7-13(21(2)20-10)14-15(22)18-9-19-16(14)25-12-6-4-5-11(8-12)17(23)24-3/h4-6,8-9,13H,7H2,1-3H3,(H,18,19,22) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >4.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
St. Jude Children's Research Hospital
Curated by ChEMBL
| Assay Description Inhibition of 6xHis-tagged NPM-ALK using biotinylated-poly(GT) peptide as substrate after 60 mins |
Bioorg Med Chem Lett 21: 4592-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.05.103 BindingDB Entry DOI: 10.7270/Q2N87B4V |
More data for this Ligand-Target Pair | |
ALK tyrosine kinase receptor
(Homo sapiens (Human)) | BDBM50348970
(CHEMBL1808108)Show InChI InChI=1S/C16H16N2O5/c1-10(19)6-7-13-14(20)17-9-18-15(13)23-12-5-3-4-11(8-12)16(21)22-2/h3-5,8-9H,6-7H2,1-2H3,(H,17,18,20) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | >4.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
St. Jude Children's Research Hospital
Curated by ChEMBL
| Assay Description Inhibition of 6xHis-tagged NPM-ALK using biotinylated-poly(GT) peptide as substrate after 60 mins |
Bioorg Med Chem Lett 21: 4592-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.05.103 BindingDB Entry DOI: 10.7270/Q2N87B4V |
More data for this Ligand-Target Pair | |
Insulin receptor
(Homo sapiens (Human)) | BDBM50348950
(CHEMBL1807771)Show SMILES CC(=O)C=Cc1c(Oc2cccc(c2)C#N)nc[nH]c1=O |w:4.4| Show InChI InChI=1S/C15H11N3O3/c1-10(19)5-6-13-14(20)17-9-18-15(13)21-12-4-2-3-11(7-12)8-16/h2-7,9H,1H3,(H,17,18,20) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >4.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
St. Jude Children's Research Hospital
Curated by ChEMBL
| Assay Description Inhibition of recombinant IRK using biotinylated-poly(GT) peptide as substrate after 60 mins |
Bioorg Med Chem Lett 21: 4592-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.05.103 BindingDB Entry DOI: 10.7270/Q2N87B4V |
More data for this Ligand-Target Pair | |
Insulin receptor
(Homo sapiens (Human)) | BDBM50348952
(CHEMBL1808087)Show SMILES COc1cc(Cl)ccc1Oc1nc[nH]c(=O)c1C=CC(C)=O |w:17.18| Show InChI InChI=1S/C15H13ClN2O4/c1-9(19)3-5-11-14(20)17-8-18-15(11)22-12-6-4-10(16)7-13(12)21-2/h3-8H,1-2H3,(H,17,18,20) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >4.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
St. Jude Children's Research Hospital
Curated by ChEMBL
| Assay Description Inhibition of recombinant IRK using biotinylated-poly(GT) peptide as substrate after 60 mins |
Bioorg Med Chem Lett 21: 4592-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.05.103 BindingDB Entry DOI: 10.7270/Q2N87B4V |
More data for this Ligand-Target Pair | |
Insulin receptor
(Homo sapiens (Human)) | BDBM50348949
(CHEMBL1807770)Show SMILES CCOC(=O)C=Cc1c(Oc2c(OC)cccc2OC)nc[nH]c1=O |w:6.6| Show InChI InChI=1S/C17H18N2O6/c1-4-24-14(20)9-8-11-16(21)18-10-19-17(11)25-15-12(22-2)6-5-7-13(15)23-3/h5-10H,4H2,1-3H3,(H,18,19,21) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >4.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
St. Jude Children's Research Hospital
Curated by ChEMBL
| Assay Description Inhibition of recombinant IRK using biotinylated-poly(GT) peptide as substrate after 60 mins |
Bioorg Med Chem Lett 21: 4592-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.05.103 BindingDB Entry DOI: 10.7270/Q2N87B4V |
More data for this Ligand-Target Pair | |
Insulin receptor
(Homo sapiens (Human)) | BDBM50348948
(CHEMBL1807769)Show SMILES COc1cccc(OC)c1Oc1nc[nH]c(=O)c1C=CC(C)=O |w:18.19| Show InChI InChI=1S/C16H16N2O5/c1-10(19)7-8-11-15(20)17-9-18-16(11)23-14-12(21-2)5-4-6-13(14)22-3/h4-9H,1-3H3,(H,17,18,20) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >4.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
St. Jude Children's Research Hospital
Curated by ChEMBL
| Assay Description Inhibition of recombinant IRK using biotinylated-poly(GT) peptide as substrate after 60 mins |
Bioorg Med Chem Lett 21: 4592-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.05.103 BindingDB Entry DOI: 10.7270/Q2N87B4V |
More data for this Ligand-Target Pair | |
ALK tyrosine kinase receptor
(Homo sapiens (Human)) | BDBM50348977
(CHEMBL1808226)Show SMILES COC(=O)c1cccc(Oc2nc[nH]c(=O)c2-c2cccc(C)c2)c1 Show InChI InChI=1S/C19H16N2O4/c1-12-5-3-6-13(9-12)16-17(22)20-11-21-18(16)25-15-8-4-7-14(10-15)19(23)24-2/h3-11H,1-2H3,(H,20,21,22) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >4.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
St. Jude Children's Research Hospital
Curated by ChEMBL
| Assay Description Inhibition of 6xHis-tagged NPM-ALK using biotinylated-poly(GT) peptide as substrate after 60 mins |
Bioorg Med Chem Lett 21: 4592-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.05.103 BindingDB Entry DOI: 10.7270/Q2N87B4V |
More data for this Ligand-Target Pair | |
ALK tyrosine kinase receptor
(Homo sapiens (Human)) | BDBM50348976
(CHEMBL1808225)Show InChI InChI=1S/C18H14N2O4/c1-23-18(22)13-8-5-9-14(10-13)24-17-15(16(21)19-11-20-17)12-6-3-2-4-7-12/h2-11H,1H3,(H,19,20,21) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >4.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
St. Jude Children's Research Hospital
Curated by ChEMBL
| Assay Description Inhibition of 6xHis-tagged NPM-ALK using biotinylated-poly(GT) peptide as substrate after 60 mins |
Bioorg Med Chem Lett 21: 4592-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.05.103 BindingDB Entry DOI: 10.7270/Q2N87B4V |
More data for this Ligand-Target Pair | |
ALK tyrosine kinase receptor
(Homo sapiens (Human)) | BDBM50348975
(CHEMBL1808224)Show SMILES COC(=O)c1cccc(Oc2nc[nH]c(=O)c2-c2cccc(OC)c2)c1 Show InChI InChI=1S/C19H16N2O5/c1-24-14-7-3-5-12(9-14)16-17(22)20-11-21-18(16)26-15-8-4-6-13(10-15)19(23)25-2/h3-11H,1-2H3,(H,20,21,22) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >4.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
St. Jude Children's Research Hospital
Curated by ChEMBL
| Assay Description Inhibition of 6xHis-tagged NPM-ALK using biotinylated-poly(GT) peptide as substrate after 60 mins |
Bioorg Med Chem Lett 21: 4592-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.05.103 BindingDB Entry DOI: 10.7270/Q2N87B4V |
More data for this Ligand-Target Pair | |
Insulin receptor
(Homo sapiens (Human)) | BDBM50348953
(CHEMBL1808088)Show SMILES CCOC(=O)C=Cc1c(Oc2ccc(Cl)cc2OC)nc[nH]c1=O |w:6.6| Show InChI InChI=1S/C16H15ClN2O5/c1-3-23-14(20)7-5-11-15(21)18-9-19-16(11)24-12-6-4-10(17)8-13(12)22-2/h4-9H,3H2,1-2H3,(H,18,19,21) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >4.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
St. Jude Children's Research Hospital
Curated by ChEMBL
| Assay Description Inhibition of recombinant IRK using biotinylated-poly(GT) peptide as substrate after 60 mins |
Bioorg Med Chem Lett 21: 4592-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.05.103 BindingDB Entry DOI: 10.7270/Q2N87B4V |
More data for this Ligand-Target Pair | |
ALK tyrosine kinase receptor
(Homo sapiens (Human)) | BDBM50348974
(CHEMBL1808223)Show SMILES COC(=O)c1cccc(Oc2nc[nH]c(=O)c2-c2cccc(N)c2)c1 Show InChI InChI=1S/C18H15N3O4/c1-24-18(23)12-5-3-7-14(9-12)25-17-15(16(22)20-10-21-17)11-4-2-6-13(19)8-11/h2-10H,19H2,1H3,(H,20,21,22) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >4.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
St. Jude Children's Research Hospital
Curated by ChEMBL
| Assay Description Inhibition of 6xHis-tagged NPM-ALK using biotinylated-poly(GT) peptide as substrate after 60 mins |
Bioorg Med Chem Lett 21: 4592-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.05.103 BindingDB Entry DOI: 10.7270/Q2N87B4V |
More data for this Ligand-Target Pair | |
Insulin receptor
(Homo sapiens (Human)) | BDBM50348964
(CHEMBL1808101)Show SMILES CC(=O)C=Cc1c(Oc2ccc(C)cc2C(C)=O)nc[nH]c1=O |w:4.4| Show InChI InChI=1S/C17H16N2O4/c1-10-4-7-15(14(8-10)12(3)21)23-17-13(6-5-11(2)20)16(22)18-9-19-17/h4-9H,1-3H3,(H,18,19,22) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >4.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
St. Jude Children's Research Hospital
Curated by ChEMBL
| Assay Description Inhibition of recombinant IRK using biotinylated-poly(GT) peptide as substrate after 60 mins |
Bioorg Med Chem Lett 21: 4592-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.05.103 BindingDB Entry DOI: 10.7270/Q2N87B4V |
More data for this Ligand-Target Pair | |
Insulin receptor
(Homo sapiens (Human)) | BDBM50348963
(CHEMBL1808100)Show SMILES COC(=O)c1ccc(OC)cc1Oc1nc[nH]c(=O)c1C=CC(C)=O |w:20.21| Show InChI InChI=1S/C17H16N2O6/c1-10(20)4-6-13-15(21)18-9-19-16(13)25-14-8-11(23-2)5-7-12(14)17(22)24-3/h4-9H,1-3H3,(H,18,19,21) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >4.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
St. Jude Children's Research Hospital
Curated by ChEMBL
| Assay Description Inhibition of recombinant IRK using biotinylated-poly(GT) peptide as substrate after 60 mins |
Bioorg Med Chem Lett 21: 4592-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.05.103 BindingDB Entry DOI: 10.7270/Q2N87B4V |
More data for this Ligand-Target Pair | |
Insulin receptor
(Homo sapiens (Human)) | BDBM50348962
(CHEMBL1808099)Show SMILES CC(=O)C=Cc1c(Oc2ccc(C(C)=O)c(F)c2)nc[nH]c1=O |w:4.4| Show InChI InChI=1S/C16H13FN2O4/c1-9(20)3-5-13-15(22)18-8-19-16(13)23-11-4-6-12(10(2)21)14(17)7-11/h3-8H,1-2H3,(H,18,19,22) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >4.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
St. Jude Children's Research Hospital
Curated by ChEMBL
| Assay Description Inhibition of recombinant IRK using biotinylated-poly(GT) peptide as substrate after 60 mins |
Bioorg Med Chem Lett 21: 4592-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.05.103 BindingDB Entry DOI: 10.7270/Q2N87B4V |
More data for this Ligand-Target Pair | |
Insulin receptor
(Homo sapiens (Human)) | BDBM50348967
(CHEMBL1808105)Show SMILES CCCCCCOC(=O)c1ccccc1Oc1nc[nH]c(=O)c1C=CC(C)=O |w:23.24| Show InChI InChI=1S/C21H24N2O5/c1-3-4-5-8-13-27-21(26)16-9-6-7-10-18(16)28-20-17(12-11-15(2)24)19(25)22-14-23-20/h6-7,9-12,14H,3-5,8,13H2,1-2H3,(H,22,23,25) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >4.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
St. Jude Children's Research Hospital
Curated by ChEMBL
| Assay Description Inhibition of recombinant IRK using biotinylated-poly(GT) peptide as substrate after 60 mins |
Bioorg Med Chem Lett 21: 4592-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.05.103 BindingDB Entry DOI: 10.7270/Q2N87B4V |
More data for this Ligand-Target Pair | |
Insulin receptor
(Homo sapiens (Human)) | BDBM50348981
(CHEMBL1808104)Show SMILES COC(=O)c1cc(Cl)ccc1Oc1nc[nH]c(=O)c1C=CC(C)=O |w:19.20| Show InChI InChI=1S/C16H13ClN2O5/c1-9(20)3-5-11-14(21)18-8-19-15(11)24-13-6-4-10(17)7-12(13)16(22)23-2/h3-8H,1-2H3,(H,18,19,21) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >4.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
St. Jude Children's Research Hospital
Curated by ChEMBL
| Assay Description Inhibition of recombinant IRK using biotinylated-poly(GT) peptide as substrate after 60 mins |
Bioorg Med Chem Lett 21: 4592-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.05.103 BindingDB Entry DOI: 10.7270/Q2N87B4V |
More data for this Ligand-Target Pair | |
Insulin receptor
(Homo sapiens (Human)) | BDBM50348966
(CHEMBL1808103)Show SMILES CC(=O)C=Cc1c(Oc2c(C)cc(cc2C)C(C)=O)nc[nH]c1=O |w:4.4| Show InChI InChI=1S/C18H18N2O4/c1-10-7-14(13(4)22)8-11(2)16(10)24-18-15(6-5-12(3)21)17(23)19-9-20-18/h5-9H,1-4H3,(H,19,20,23) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >4.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
St. Jude Children's Research Hospital
Curated by ChEMBL
| Assay Description Inhibition of recombinant IRK using biotinylated-poly(GT) peptide as substrate after 60 mins |
Bioorg Med Chem Lett 21: 4592-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.05.103 BindingDB Entry DOI: 10.7270/Q2N87B4V |
More data for this Ligand-Target Pair | |
Insulin receptor
(Homo sapiens (Human)) | BDBM50348965
(CHEMBL1808102)Show SMILES CCOC(=O)c1ccccc1Oc1nc[nH]c(=O)c1C=CC(C)=O |w:19.20| Show InChI InChI=1S/C17H16N2O5/c1-3-23-17(22)12-6-4-5-7-14(12)24-16-13(9-8-11(2)20)15(21)18-10-19-16/h4-10H,3H2,1-2H3,(H,18,19,21) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >4.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
St. Jude Children's Research Hospital
Curated by ChEMBL
| Assay Description Inhibition of recombinant IRK using biotinylated-poly(GT) peptide as substrate after 60 mins |
Bioorg Med Chem Lett 21: 4592-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.05.103 BindingDB Entry DOI: 10.7270/Q2N87B4V |
More data for this Ligand-Target Pair | |
ALK tyrosine kinase receptor
(Homo sapiens (Human)) | BDBM50348947
(CHEMBL1807768)Show SMILES CCOC(=O)C=Cc1c(Oc2ccc(OC)cc2C(=O)OC)nc[nH]c1=O |w:6.6| Show InChI InChI=1S/C18H18N2O7/c1-4-26-15(21)8-6-12-16(22)19-10-20-17(12)27-14-7-5-11(24-2)9-13(14)18(23)25-3/h5-10H,4H2,1-3H3,(H,19,20,22) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >4.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
St. Jude Children's Research Hospital
Curated by ChEMBL
| Assay Description Inhibition of 6xHis-tagged NPM-ALK using biotinylated-poly(GT) peptide as substrate after 60 mins |
Bioorg Med Chem Lett 21: 4592-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.05.103 BindingDB Entry DOI: 10.7270/Q2N87B4V |
More data for this Ligand-Target Pair | |
ALK tyrosine kinase receptor
(Homo sapiens (Human)) | BDBM50348946
(CHEMBL1807767)Show SMILES COC(=O)c1cc(OC)ccc1Oc1nc[nH]c(=O)c1C=CC(C)=O |w:20.21| Show InChI InChI=1S/C17H16N2O6/c1-10(20)4-6-12-15(21)18-9-19-16(12)25-14-7-5-11(23-2)8-13(14)17(22)24-3/h4-9H,1-3H3,(H,18,19,21) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >4.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
St. Jude Children's Research Hospital
Curated by ChEMBL
| Assay Description Inhibition of 6xHis-tagged NPM-ALK using biotinylated-poly(GT) peptide as substrate after 60 mins |
Bioorg Med Chem Lett 21: 4592-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.05.103 BindingDB Entry DOI: 10.7270/Q2N87B4V |
More data for this Ligand-Target Pair | |
ALK tyrosine kinase receptor
(Homo sapiens (Human)) | BDBM50348937
(CHEMBL1807766)Show SMILES CCOC(=O)C=Cc1c(Oc2ccc(F)cc2)nc[nH]c1=O |w:6.6| Show InChI InChI=1S/C15H13FN2O4/c1-2-21-13(19)8-7-12-14(20)17-9-18-15(12)22-11-5-3-10(16)4-6-11/h3-9H,2H2,1H3,(H,17,18,20) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >4.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
St. Jude Children's Research Hospital
Curated by ChEMBL
| Assay Description Inhibition of 6xHis-tagged NPM-ALK using biotinylated-poly(GT) peptide as substrate after 60 mins |
Bioorg Med Chem Lett 21: 4592-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.05.103 BindingDB Entry DOI: 10.7270/Q2N87B4V |
More data for this Ligand-Target Pair | |
ALK tyrosine kinase receptor
(Homo sapiens (Human)) | BDBM50348939
(CHEMBL1807765)Show SMILES CC(=O)C=Cc1c(Oc2ccc(F)cc2)nc[nH]c1=O |w:4.4| Show InChI InChI=1S/C14H11FN2O3/c1-9(18)2-7-12-13(19)16-8-17-14(12)20-11-5-3-10(15)4-6-11/h2-8H,1H3,(H,16,17,19) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >4.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
St. Jude Children's Research Hospital
Curated by ChEMBL
| Assay Description Inhibition of 6xHis-tagged NPM-ALK using biotinylated-poly(GT) peptide as substrate after 60 mins |
Bioorg Med Chem Lett 21: 4592-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.05.103 BindingDB Entry DOI: 10.7270/Q2N87B4V |
More data for this Ligand-Target Pair | |
ALK tyrosine kinase receptor
(Homo sapiens (Human)) | BDBM50348941
(CHEMBL1807764)Show SMILES CCOC(=O)C=Cc1c(Oc2ccccc2Cl)nc[nH]c1=O |w:6.6| Show InChI InChI=1S/C15H13ClN2O4/c1-2-21-13(19)8-7-10-14(20)17-9-18-15(10)22-12-6-4-3-5-11(12)16/h3-9H,2H2,1H3,(H,17,18,20) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >4.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
St. Jude Children's Research Hospital
Curated by ChEMBL
| Assay Description Inhibition of 6xHis-tagged NPM-ALK using biotinylated-poly(GT) peptide as substrate after 60 mins |
Bioorg Med Chem Lett 21: 4592-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.05.103 BindingDB Entry DOI: 10.7270/Q2N87B4V |
More data for this Ligand-Target Pair | |
ALK tyrosine kinase receptor
(Homo sapiens (Human)) | BDBM50348943
(CHEMBL1807763)Show SMILES CC(=O)C=Cc1c(Oc2ccccc2Cl)nc[nH]c1=O |w:4.4| Show InChI InChI=1S/C14H11ClN2O3/c1-9(18)6-7-10-13(19)16-8-17-14(10)20-12-5-3-2-4-11(12)15/h2-8H,1H3,(H,16,17,19) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >4.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
St. Jude Children's Research Hospital
Curated by ChEMBL
| Assay Description Inhibition of 6xHis-tagged NPM-ALK using biotinylated-poly(GT) peptide as substrate after 60 mins |
Bioorg Med Chem Lett 21: 4592-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.05.103 BindingDB Entry DOI: 10.7270/Q2N87B4V |
More data for this Ligand-Target Pair | |
ALK tyrosine kinase receptor
(Homo sapiens (Human)) | BDBM50348944
(CHEMBL1807762)Show SMILES CCOC(=O)C=Cc1c(Oc2ccc(cc2)C(C)(C)C)nc[nH]c1=O |w:6.6| Show InChI InChI=1S/C19H22N2O4/c1-5-24-16(22)11-10-15-17(23)20-12-21-18(15)25-14-8-6-13(7-9-14)19(2,3)4/h6-12H,5H2,1-4H3,(H,20,21,23) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >4.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
St. Jude Children's Research Hospital
Curated by ChEMBL
| Assay Description Inhibition of 6xHis-tagged NPM-ALK using biotinylated-poly(GT) peptide as substrate after 60 mins |
Bioorg Med Chem Lett 21: 4592-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.05.103 BindingDB Entry DOI: 10.7270/Q2N87B4V |
More data for this Ligand-Target Pair | |
ALK tyrosine kinase receptor
(Homo sapiens (Human)) | BDBM50348938
(CHEMBL1807761)Show SMILES CC(=O)C=Cc1c(Oc2ccc(cc2)C(C)(C)C)nc[nH]c1=O |w:4.4| Show InChI InChI=1S/C18H20N2O3/c1-12(21)5-10-15-16(22)19-11-20-17(15)23-14-8-6-13(7-9-14)18(2,3)4/h5-11H,1-4H3,(H,19,20,22) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >4.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
St. Jude Children's Research Hospital
Curated by ChEMBL
| Assay Description Inhibition of 6xHis-tagged NPM-ALK using biotinylated-poly(GT) peptide as substrate after 60 mins |
Bioorg Med Chem Lett 21: 4592-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.05.103 BindingDB Entry DOI: 10.7270/Q2N87B4V |
More data for this Ligand-Target Pair | |
ALK tyrosine kinase receptor
(Homo sapiens (Human)) | BDBM50348940
(CHEMBL1807760)Show SMILES CCOC(=O)C=Cc1c(Oc2ccc(C)cc2)nc[nH]c1=O |w:6.6| Show InChI InChI=1S/C16H16N2O4/c1-3-21-14(19)9-8-13-15(20)17-10-18-16(13)22-12-6-4-11(2)5-7-12/h4-10H,3H2,1-2H3,(H,17,18,20) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >4.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
St. Jude Children's Research Hospital
Curated by ChEMBL
| Assay Description Inhibition of 6xHis-tagged NPM-ALK using biotinylated-poly(GT) peptide as substrate after 60 mins |
Bioorg Med Chem Lett 21: 4592-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.05.103 BindingDB Entry DOI: 10.7270/Q2N87B4V |
More data for this Ligand-Target Pair | |