Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Prostaglandin E synthase (Homo sapiens (Human)) | BDBM50227631 (2-(6-chloro-1H-phenanthro[9,10-d]imidazol-2-yl)iso...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | 4.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Dainippon Sumitomo Pharma. Co. Ltd Curated by ChEMBL | Assay Description Inhibition of microsomal PGES1 transfected in human HEK293 cells assessed as PGE2 production after 60 mins by HTRF assay | Bioorg Med Chem Lett 22: 285-8 (2011) Article DOI: 10.1016/j.bmcl.2011.11.015 BindingDB Entry DOI: 10.7270/Q2PR7WFN | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Prostaglandin E synthase (Homo sapiens (Human)) | BDBM50360832 (CHEMBL1934810) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 9.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Dainippon Sumitomo Pharma. Co. Ltd Curated by ChEMBL | Assay Description Inhibition of microsomal PGES1 transfected in human HEK293 cells assessed as PGE2 production after 60 mins by HTRF assay | Bioorg Med Chem Lett 22: 285-8 (2011) Article DOI: 10.1016/j.bmcl.2011.11.015 BindingDB Entry DOI: 10.7270/Q2PR7WFN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E synthase (Homo sapiens (Human)) | BDBM50360830 (CHEMBL1934808) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 62 | n/a | n/a | n/a | n/a | n/a | n/a |
Dainippon Sumitomo Pharma. Co. Ltd Curated by ChEMBL | Assay Description Inhibition of microsomal PGES1 transfected in human HEK293 cells assessed as PGE2 production after 60 mins by HTRF assay | Bioorg Med Chem Lett 22: 285-8 (2011) Article DOI: 10.1016/j.bmcl.2011.11.015 BindingDB Entry DOI: 10.7270/Q2PR7WFN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E synthase (Homo sapiens (Human)) | BDBM50360831 (CHEMBL1934809) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 108 | n/a | n/a | n/a | n/a | n/a | n/a |
Dainippon Sumitomo Pharma. Co. Ltd Curated by ChEMBL | Assay Description Inhibition of microsomal PGES1 transfected in human HEK293 cells assessed as PGE2 production after 60 mins by HTRF assay | Bioorg Med Chem Lett 22: 285-8 (2011) Article DOI: 10.1016/j.bmcl.2011.11.015 BindingDB Entry DOI: 10.7270/Q2PR7WFN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E synthase (Homo sapiens (Human)) | BDBM50360829 (CHEMBL1934807) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 172 | n/a | n/a | n/a | n/a | n/a | n/a |
Dainippon Sumitomo Pharma. Co. Ltd Curated by ChEMBL | Assay Description Inhibition of microsomal PGES1 transfected in human HEK293 cells assessed as PGE2 production after 60 mins by HTRF assay | Bioorg Med Chem Lett 22: 285-8 (2011) Article DOI: 10.1016/j.bmcl.2011.11.015 BindingDB Entry DOI: 10.7270/Q2PR7WFN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E synthase (Homo sapiens (Human)) | BDBM50360813 (CHEMBL1934791) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 251 | n/a | n/a | n/a | n/a | n/a | n/a |
Dainippon Sumitomo Pharma. Co. Ltd Curated by ChEMBL | Assay Description Inhibition of microsomal PGES1 transfected in human HEK293 cells assessed as PGE2 production after 60 mins by HTRF assay | Bioorg Med Chem Lett 22: 285-8 (2011) Article DOI: 10.1016/j.bmcl.2011.11.015 BindingDB Entry DOI: 10.7270/Q2PR7WFN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E synthase (Homo sapiens (Human)) | BDBM50360828 (CHEMBL1934806) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 306 | n/a | n/a | n/a | n/a | n/a | n/a |
Dainippon Sumitomo Pharma. Co. Ltd Curated by ChEMBL | Assay Description Inhibition of microsomal PGES1 transfected in human HEK293 cells assessed as PGE2 production after 60 mins by HTRF assay | Bioorg Med Chem Lett 22: 285-8 (2011) Article DOI: 10.1016/j.bmcl.2011.11.015 BindingDB Entry DOI: 10.7270/Q2PR7WFN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E synthase (Homo sapiens (Human)) | BDBM50360827 (CHEMBL1934805) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 330 | n/a | n/a | n/a | n/a | n/a | n/a |
Dainippon Sumitomo Pharma. Co. Ltd Curated by ChEMBL | Assay Description Inhibition of microsomal PGES1 transfected in human HEK293 cells assessed as PGE2 production after 60 mins by HTRF assay | Bioorg Med Chem Lett 22: 285-8 (2011) Article DOI: 10.1016/j.bmcl.2011.11.015 BindingDB Entry DOI: 10.7270/Q2PR7WFN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E synthase (Homo sapiens (Human)) | BDBM50360816 (CHEMBL1934794) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 395 | n/a | n/a | n/a | n/a | n/a | n/a |
Dainippon Sumitomo Pharma. Co. Ltd Curated by ChEMBL | Assay Description Inhibition of microsomal PGES1 transfected in human HEK293 cells assessed as PGE2 production after 60 mins by HTRF assay | Bioorg Med Chem Lett 22: 285-8 (2011) Article DOI: 10.1016/j.bmcl.2011.11.015 BindingDB Entry DOI: 10.7270/Q2PR7WFN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E synthase (Homo sapiens (Human)) | BDBM50360819 (CHEMBL1934797) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 506 | n/a | n/a | n/a | n/a | n/a | n/a |
Dainippon Sumitomo Pharma. Co. Ltd Curated by ChEMBL | Assay Description Inhibition of microsomal PGES1 transfected in human HEK293 cells assessed as PGE2 production after 60 mins by HTRF assay | Bioorg Med Chem Lett 22: 285-8 (2011) Article DOI: 10.1016/j.bmcl.2011.11.015 BindingDB Entry DOI: 10.7270/Q2PR7WFN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E synthase (Homo sapiens (Human)) | BDBM50360823 (CHEMBL1934801) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 669 | n/a | n/a | n/a | n/a | n/a | n/a |
Dainippon Sumitomo Pharma. Co. Ltd Curated by ChEMBL | Assay Description Inhibition of microsomal PGES1 transfected in human HEK293 cells assessed as PGE2 production after 60 mins by HTRF assay | Bioorg Med Chem Lett 22: 285-8 (2011) Article DOI: 10.1016/j.bmcl.2011.11.015 BindingDB Entry DOI: 10.7270/Q2PR7WFN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E synthase (Homo sapiens (Human)) | BDBM50360824 (CHEMBL1934802) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 687 | n/a | n/a | n/a | n/a | n/a | n/a |
Dainippon Sumitomo Pharma. Co. Ltd Curated by ChEMBL | Assay Description Inhibition of microsomal PGES1 transfected in human HEK293 cells assessed as PGE2 production after 60 mins by HTRF assay | Bioorg Med Chem Lett 22: 285-8 (2011) Article DOI: 10.1016/j.bmcl.2011.11.015 BindingDB Entry DOI: 10.7270/Q2PR7WFN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E synthase (Homo sapiens (Human)) | BDBM50360814 (CHEMBL1934792) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 859 | n/a | n/a | n/a | n/a | n/a | n/a |
Dainippon Sumitomo Pharma. Co. Ltd Curated by ChEMBL | Assay Description Inhibition of microsomal PGES1 transfected in human HEK293 cells assessed as PGE2 production after 60 mins by HTRF assay | Bioorg Med Chem Lett 22: 285-8 (2011) Article DOI: 10.1016/j.bmcl.2011.11.015 BindingDB Entry DOI: 10.7270/Q2PR7WFN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E synthase (Homo sapiens (Human)) | BDBM50360822 (CHEMBL1934800) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Dainippon Sumitomo Pharma. Co. Ltd Curated by ChEMBL | Assay Description Inhibition of microsomal PGES1 transfected in human HEK293 cells assessed as PGE2 production after 60 mins by HTRF assay | Bioorg Med Chem Lett 22: 285-8 (2011) Article DOI: 10.1016/j.bmcl.2011.11.015 BindingDB Entry DOI: 10.7270/Q2PR7WFN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E synthase (Homo sapiens (Human)) | BDBM50360817 (CHEMBL1934795) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.49E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Dainippon Sumitomo Pharma. Co. Ltd Curated by ChEMBL | Assay Description Inhibition of microsomal PGES1 transfected in human HEK293 cells assessed as PGE2 production after 60 mins by HTRF assay | Bioorg Med Chem Lett 22: 285-8 (2011) Article DOI: 10.1016/j.bmcl.2011.11.015 BindingDB Entry DOI: 10.7270/Q2PR7WFN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E synthase (Homo sapiens (Human)) | BDBM50360826 (CHEMBL1934804) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.12E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Dainippon Sumitomo Pharma. Co. Ltd Curated by ChEMBL | Assay Description Inhibition of microsomal PGES1 transfected in human HEK293 cells assessed as PGE2 production after 60 mins by HTRF assay | Bioorg Med Chem Lett 22: 285-8 (2011) Article DOI: 10.1016/j.bmcl.2011.11.015 BindingDB Entry DOI: 10.7270/Q2PR7WFN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E synthase (Homo sapiens (Human)) | BDBM50360821 (CHEMBL1934799) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.62E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Dainippon Sumitomo Pharma. Co. Ltd Curated by ChEMBL | Assay Description Inhibition of microsomal PGES1 transfected in human HEK293 cells assessed as PGE2 production after 60 mins by HTRF assay | Bioorg Med Chem Lett 22: 285-8 (2011) Article DOI: 10.1016/j.bmcl.2011.11.015 BindingDB Entry DOI: 10.7270/Q2PR7WFN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E synthase (Homo sapiens (Human)) | BDBM50360825 (CHEMBL1934803) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 6.26E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Dainippon Sumitomo Pharma. Co. Ltd Curated by ChEMBL | Assay Description Inhibition of microsomal PGES1 transfected in human HEK293 cells assessed as PGE2 production after 60 mins by HTRF assay | Bioorg Med Chem Lett 22: 285-8 (2011) Article DOI: 10.1016/j.bmcl.2011.11.015 BindingDB Entry DOI: 10.7270/Q2PR7WFN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E synthase (Homo sapiens (Human)) | BDBM50360820 (CHEMBL1934798) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 6.97E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Dainippon Sumitomo Pharma. Co. Ltd Curated by ChEMBL | Assay Description Inhibition of microsomal PGES1 transfected in human HEK293 cells assessed as PGE2 production after 60 mins by HTRF assay | Bioorg Med Chem Lett 22: 285-8 (2011) Article DOI: 10.1016/j.bmcl.2011.11.015 BindingDB Entry DOI: 10.7270/Q2PR7WFN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E synthase (Homo sapiens (Human)) | BDBM50360812 (CHEMBL1934678) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 9.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Dainippon Sumitomo Pharma. Co. Ltd Curated by ChEMBL | Assay Description Inhibition of microsomal PGES1 transfected in human HEK293 cells assessed as PGE2 production after 60 mins by HTRF assay | Bioorg Med Chem Lett 22: 285-8 (2011) Article DOI: 10.1016/j.bmcl.2011.11.015 BindingDB Entry DOI: 10.7270/Q2PR7WFN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E synthase (Homo sapiens (Human)) | BDBM50360815 (CHEMBL1934793) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Dainippon Sumitomo Pharma. Co. Ltd Curated by ChEMBL | Assay Description Inhibition of microsomal PGES1 transfected in human HEK293 cells assessed as PGE2 production after 60 mins by HTRF assay | Bioorg Med Chem Lett 22: 285-8 (2011) Article DOI: 10.1016/j.bmcl.2011.11.015 BindingDB Entry DOI: 10.7270/Q2PR7WFN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin E synthase (Homo sapiens (Human)) | BDBM50360818 (CHEMBL1934796) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Dainippon Sumitomo Pharma. Co. Ltd Curated by ChEMBL | Assay Description Inhibition of microsomal PGES1 transfected in human HEK293 cells assessed as PGE2 production after 60 mins by HTRF assay | Bioorg Med Chem Lett 22: 285-8 (2011) Article DOI: 10.1016/j.bmcl.2011.11.015 BindingDB Entry DOI: 10.7270/Q2PR7WFN | |||||||||||
More data for this Ligand-Target Pair |