Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1) | BDBM50085033 (5,6-Difluoro-1H-quinazolin-2-one | CHEMBL57995) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | n/a | n/a | 18 | n/a | n/a | n/a | n/a | n/a | n/a |
DuPont Pharmaceuticals Company Curated by ChEMBL | Assay Description The compound was evaluated for the inhibition of HIV-1 reverse transcriptase | Bioorg Med Chem Lett 10: 193-5 (2000) BindingDB Entry DOI: 10.7270/Q21G0MSH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1) | BDBM2898 ((4S)-6-chloro-4-(2-cyclopropylethynyl)-4-(trifluor...) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | PubMed | n/a | n/a | 31 | n/a | n/a | n/a | n/a | n/a | n/a |
DuPont Pharmaceuticals Company Curated by ChEMBL | Assay Description The compound was evaluated for the inhibition of HIV-1 reverse transcriptase | Bioorg Med Chem Lett 10: 193-5 (2000) BindingDB Entry DOI: 10.7270/Q21G0MSH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1) | BDBM2483 ((4S)-6-chloro-4-(2-cyclopropylethynyl)-4-(trifluor...) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | DrugBank MMDB PDB PubMed | n/a | n/a | 47 | n/a | n/a | n/a | n/a | n/a | n/a |
DuPont Pharmaceuticals Company Curated by ChEMBL | Assay Description The compound was evaluated for the inhibition of HIV-1 reverse transcriptase | Bioorg Med Chem Lett 10: 193-5 (2000) BindingDB Entry DOI: 10.7270/Q21G0MSH | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1) | BDBM50085035 (6-Chloro-4-isopropyl-4-(3-methyl-but-1-ynyl)-3,4-d...) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 137 | n/a | n/a | n/a | n/a | n/a | n/a |
DuPont Pharmaceuticals Company Curated by ChEMBL | Assay Description The compound was evaluated for the inhibition of HIV-1 reverse transcriptase | Bioorg Med Chem Lett 10: 193-5 (2000) BindingDB Entry DOI: 10.7270/Q21G0MSH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1) | BDBM1944 (BHAP deriv. | CHEMBL593 | DELAVIRDINE MESYLATE | D...) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | DrugBank MMDB PDB PubMed | n/a | n/a | 422 | n/a | n/a | n/a | n/a | n/a | n/a |
DuPont Pharmaceuticals Company Curated by ChEMBL | Assay Description The compound was evaluated for the inhibition of HIV-1 reverse transcriptase | Bioorg Med Chem Lett 10: 193-5 (2000) BindingDB Entry DOI: 10.7270/Q21G0MSH | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1) | BDBM50085038 (6-Chloro-4-cyclopropyl-4-(3-methyl-but-1-ynyl)-3,4...) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 4.63E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
DuPont Pharmaceuticals Company Curated by ChEMBL | Assay Description The compound was evaluated for the inhibition of HIV-1 reverse transcriptase | Bioorg Med Chem Lett 10: 193-5 (2000) BindingDB Entry DOI: 10.7270/Q21G0MSH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1) | BDBM1434 (11-cyclopropyl-5,11-dihydro-4-methyl-6H-dipyrido[3...) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | DrugBank MMDB PDB PubMed | n/a | n/a | 4.85E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
DuPont Pharmaceuticals Company Curated by ChEMBL | Assay Description The compound was evaluated for the inhibition of HIV-1 reverse transcriptase | Bioorg Med Chem Lett 10: 193-5 (2000) BindingDB Entry DOI: 10.7270/Q21G0MSH | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1) | BDBM50085036 (4-Cyclopropylethynyl-5,6-difluoro-4-trifluoromethy...) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | PubMed | n/a | n/a | 2.47E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
DuPont Pharmaceuticals Company Curated by ChEMBL | Assay Description The compound was evaluated for the inhibition of HIV-1 reverse transcriptase | Bioorg Med Chem Lett 10: 193-5 (2000) BindingDB Entry DOI: 10.7270/Q21G0MSH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Reverse transcriptase/RNaseH (Human immunodeficiency virus 1) | BDBM50085037 (6-Chloro-4-cyclopropyl-4-cyclopropylethynyl-3,4-di...) | PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 3.59E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
DuPont Pharmaceuticals Company Curated by ChEMBL | Assay Description The compound was evaluated for the inhibition of HIV-1 reverse transcriptase | Bioorg Med Chem Lett 10: 193-5 (2000) BindingDB Entry DOI: 10.7270/Q21G0MSH | |||||||||||
More data for this Ligand-Target Pair |