Compile Data Set for Download or QSAR

Found 55 hits Enz. Inhib. hit(s) with all data for entry = 50000333   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 8 (Homo sapiens (Human))	BDBM50246866 (CHEMBL4078458 | US11505523, Compound 22d) Show SMILES COc1ccc(\C=C\C(=O)NO)c(c1)-c1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C22H19NO3/c1-26-20-13-11-19(12-14-22(24)23-25)21(15-20)18-9-7-17(8-10-18)16-5-3-2-4-6-16/h2-15,25H,1H3,(H,23,24)/b14-12+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
Martin-Luther University of Halle-Wittenberg Curated by ChEMBL					Assay Description Inhibition of human HDAC8 (1 to 377 residues) expressed in Escherichia coli BL21(DE3) using Boc-Lys(TFA)-AMC as substrate preincubated for 5 mins fol...				J Med Chem 60: 10188-10204 (2017) Article DOI: 10.1021/acs.jmedchem.7b01447 BindingDB Entry DOI: 10.7270/Q2DZ0BQJ
					More data for this Ligand-Target Pair
Histone deacetylase 8 (Homo sapiens (Human))	BDBM50164532 (CHEMBL3797516) Show SMILES COc1ccc(cc1OCc1ccccc1)C(=O)NO Show InChI InChI=1S/C15H15NO4/c1-19-13-8-7-12(15(17)16-18)9-14(13)20-10-11-5-3-2-4-6-11/h2-9,18H,10H2,1H3,(H,16,17)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
Martin-Luther University of Halle-Wittenberg Curated by ChEMBL					Assay Description Inhibition of recombinant human full length C-terminal His-tagged HDAC8 expressed in Escherichia coli BL21(DE3) using fluor de Lys(R) as substrate af...				J Med Chem 60: 10188-10204 (2017) Article DOI: 10.1021/acs.jmedchem.7b01447 BindingDB Entry DOI: 10.7270/Q2DZ0BQJ
					More data for this Ligand-Target Pair
Histone deacetylase 8 (Homo sapiens (Human))	BDBM50246847 (CHEMBL4089635) Show SMILES Cc1ccc(cc1NCc1ccc(Cl)cc1Cl)C(=O)NO Show InChI InChI=1S/C15H14Cl2N2O2/c1-9-2-3-10(15(20)19-21)6-14(9)18-8-11-4-5-12(16)7-13(11)17/h2-7,18,21H,8H2,1H3,(H,19,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
Martin-Luther University of Halle-Wittenberg Curated by ChEMBL					Assay Description Inhibition of recombinant human full length C-terminal His-tagged HDAC8 expressed in Escherichia coli BL21(DE3) using fluor de Lys(R) as substrate af...				J Med Chem 60: 10188-10204 (2017) Article DOI: 10.1021/acs.jmedchem.7b01447 BindingDB Entry DOI: 10.7270/Q2DZ0BQJ
					More data for this Ligand-Target Pair
Histone deacetylase 8 (Homo sapiens (Human))	BDBM50246874 (CHEMBL4095643) Show SMILES COc1ccc(cc1C(=O)Nc1ccc(Cl)cc1)C(=O)NO Show InChI InChI=1S/C15H13ClN2O4/c1-22-13-7-2-9(14(19)18-21)8-12(13)15(20)17-11-5-3-10(16)4-6-11/h2-8,21H,1H3,(H,17,20)(H,18,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	38	n/a	n/a	n/a	n/a	n/a	n/a
Martin-Luther University of Halle-Wittenberg Curated by ChEMBL					Assay Description Inhibition of recombinant human full length C-terminal His-tagged HDAC8 expressed in Escherichia coli BL21(DE3) using fluor de Lys(R) as substrate af...				J Med Chem 60: 10188-10204 (2017) Article DOI: 10.1021/acs.jmedchem.7b01447 BindingDB Entry DOI: 10.7270/Q2DZ0BQJ
					More data for this Ligand-Target Pair
Histone deacetylase 8 (Homo sapiens (Human))	BDBM50246846 (CHEMBL4105068) Show SMILES COc1ccc(cc1NCc1ccccc1)C(=O)NO Show InChI InChI=1S/C15H16N2O3/c1-20-14-8-7-12(15(18)17-19)9-13(14)16-10-11-5-3-2-4-6-11/h2-9,16,19H,10H2,1H3,(H,17,18)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	69	n/a	n/a	n/a	n/a	n/a	n/a
Martin-Luther University of Halle-Wittenberg Curated by ChEMBL					Assay Description Inhibition of recombinant human full length C-terminal His-tagged HDAC8 expressed in Escherichia coli BL21(DE3) using fluor de Lys(R) as substrate af...				J Med Chem 60: 10188-10204 (2017) Article DOI: 10.1021/acs.jmedchem.7b01447 BindingDB Entry DOI: 10.7270/Q2DZ0BQJ
					More data for this Ligand-Target Pair
Histone deacetylase 8 (Homo sapiens (Human))	BDBM50246848 (CHEMBL4061831) Show SMILES ONC(=O)c1ccc(F)c(NCc2ccccc2)c1 Show InChI InChI=1S/C14H13FN2O2/c15-12-7-6-11(14(18)17-19)8-13(12)16-9-10-4-2-1-3-5-10/h1-8,16,19H,9H2,(H,17,18)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	72	n/a	n/a	n/a	n/a	n/a	n/a
Martin-Luther University of Halle-Wittenberg Curated by ChEMBL					Assay Description Inhibition of recombinant human full length C-terminal His-tagged HDAC8 expressed in Escherichia coli BL21(DE3) using fluor de Lys(R) as substrate af...				J Med Chem 60: 10188-10204 (2017) Article DOI: 10.1021/acs.jmedchem.7b01447 BindingDB Entry DOI: 10.7270/Q2DZ0BQJ
					More data for this Ligand-Target Pair
Histone deacetylase 8 (Homo sapiens (Human))	BDBM50397360 (CHEMBL2170177 | US10188756, Compound CN110) Show SMILES COc1ccc(Cn2ccc3ccc(cc23)C(=O)NO)cc1 Show InChI InChI=1S/C17H16N2O3/c1-22-15-6-2-12(3-7-15)11-19-9-8-13-4-5-14(10-16(13)19)17(20)18-21/h2-10,21H,11H2,1H3,(H,18,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	92	n/a	n/a	n/a	n/a	n/a	n/a
Martin-Luther University of Halle-Wittenberg Curated by ChEMBL					Assay Description Inhibition of recombinant human full length C-terminal His-tagged HDAC8 expressed in Escherichia coli BL21(DE3) using fluor de Lys(R) as substrate af...				J Med Chem 60: 10188-10204 (2017) Article DOI: 10.1021/acs.jmedchem.7b01447 BindingDB Entry DOI: 10.7270/Q2DZ0BQJ
					More data for this Ligand-Target Pair
Histone deacetylase 8 (Homo sapiens (Human))	BDBM50246864 (CHEMBL4065863) Show SMILES Cc1ccc(cc1C(=O)Nc1ccc(Cl)cc1)C(=O)NO Show InChI InChI=1S/C15H13ClN2O3/c1-9-2-3-10(14(19)18-21)8-13(9)15(20)17-12-6-4-11(16)5-7-12/h2-8,21H,1H3,(H,17,20)(H,18,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	114	n/a	n/a	n/a	n/a	n/a	n/a
Martin-Luther University of Halle-Wittenberg Curated by ChEMBL					Assay Description Inhibition of recombinant human full length C-terminal His-tagged HDAC8 expressed in Escherichia coli BL21(DE3) using fluor de Lys(R) as substrate af...				J Med Chem 60: 10188-10204 (2017) Article DOI: 10.1021/acs.jmedchem.7b01447 BindingDB Entry DOI: 10.7270/Q2DZ0BQJ
					More data for this Ligand-Target Pair
Histone deacetylase 8 (Homo sapiens (Human))	BDBM50246861 (CHEMBL4065500) Show SMILES Cc1ccc(cc1NCc1ccc2ccccc2c1)C(=O)NO Show InChI InChI=1S/C19H18N2O2/c1-13-6-8-17(19(22)21-23)11-18(13)20-12-14-7-9-15-4-2-3-5-16(15)10-14/h2-11,20,23H,12H2,1H3,(H,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	119	n/a	n/a	n/a	n/a	n/a	n/a
Martin-Luther University of Halle-Wittenberg Curated by ChEMBL					Assay Description Inhibition of recombinant human full length C-terminal His-tagged HDAC8 expressed in Escherichia coli BL21(DE3) using fluor de Lys(R) as substrate af...				J Med Chem 60: 10188-10204 (2017) Article DOI: 10.1021/acs.jmedchem.7b01447 BindingDB Entry DOI: 10.7270/Q2DZ0BQJ
					More data for this Ligand-Target Pair
Histone deacetylase 8 (Homo sapiens (Human))	BDBM50246865 (CHEMBL4077880) Show SMILES COc1ccc(cc1OCc1ccccc1Cl)C(=O)NO Show InChI InChI=1S/C15H14ClNO4/c1-20-13-7-6-10(15(18)17-19)8-14(13)21-9-11-4-2-3-5-12(11)16/h2-8,19H,9H2,1H3,(H,17,18)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Martin-Luther University of Halle-Wittenberg Curated by ChEMBL					Assay Description Inhibition of recombinant human full length C-terminal His-tagged HDAC8 expressed in Escherichia coli BL21(DE3) using fluor de Lys(R) as substrate af...				J Med Chem 60: 10188-10204 (2017) Article DOI: 10.1021/acs.jmedchem.7b01447 BindingDB Entry DOI: 10.7270/Q2DZ0BQJ
					More data for this Ligand-Target Pair
Histone deacetylase 8 (Homo sapiens (Human))	BDBM50246862 (CHEMBL2381520) Show SMILES ONC(=O)c1cccc(c1)C(=O)Nc1ccccc1 Show InChI InChI=1S/C14H12N2O3/c17-13(15-12-7-2-1-3-8-12)10-5-4-6-11(9-10)14(18)16-19/h1-9,19H,(H,15,17)(H,16,18)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Martin-Luther University of Halle-Wittenberg Curated by ChEMBL					Assay Description Inhibition of recombinant human full length C-terminal His-tagged HDAC8 expressed in Escherichia coli BL21(DE3) using fluor de Lys(R) as substrate af...				J Med Chem 60: 10188-10204 (2017) Article DOI: 10.1021/acs.jmedchem.7b01447 BindingDB Entry DOI: 10.7270/Q2DZ0BQJ
					More data for this Ligand-Target Pair
Histone deacetylase 8 (Homo sapiens (Human))	BDBM50246858 (CHEMBL4093511) Show SMILES Cc1ccc(cc1NCCc1ccccc1)C(=O)NO Show InChI InChI=1S/C16H18N2O2/c1-12-7-8-14(16(19)18-20)11-15(12)17-10-9-13-5-3-2-4-6-13/h2-8,11,17,20H,9-10H2,1H3,(H,18,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
Martin-Luther University of Halle-Wittenberg Curated by ChEMBL					Assay Description Inhibition of recombinant human full length C-terminal His-tagged HDAC8 expressed in Escherichia coli BL21(DE3) using fluor de Lys(R) as substrate af...				J Med Chem 60: 10188-10204 (2017) Article DOI: 10.1021/acs.jmedchem.7b01447 BindingDB Entry DOI: 10.7270/Q2DZ0BQJ
					More data for this Ligand-Target Pair
Histone deacetylase 8 (Homo sapiens (Human))	BDBM50246873 (CHEMBL4077076) Show SMILES CCc1ccc(cc1NCc1ccccc1)C(=O)NO Show InChI InChI=1S/C16H18N2O2/c1-2-13-8-9-14(16(19)18-20)10-15(13)17-11-12-6-4-3-5-7-12/h3-10,17,20H,2,11H2,1H3,(H,18,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	136	n/a	n/a	n/a	n/a	n/a	n/a
Martin-Luther University of Halle-Wittenberg Curated by ChEMBL					Assay Description Inhibition of recombinant human full length C-terminal His-tagged HDAC8 expressed in Escherichia coli BL21(DE3) using fluor de Lys(R) as substrate af...				J Med Chem 60: 10188-10204 (2017) Article DOI: 10.1021/acs.jmedchem.7b01447 BindingDB Entry DOI: 10.7270/Q2DZ0BQJ
					More data for this Ligand-Target Pair
Histone deacetylase 8 (Homo sapiens (Human))	BDBM50246872 (CHEMBL4094005) Show SMILES COc1ccc(cc1NCc1ccc(Cl)cc1)C(=O)NO Show InChI InChI=1S/C15H15ClN2O3/c1-21-14-7-4-11(15(19)18-20)8-13(14)17-9-10-2-5-12(16)6-3-10/h2-8,17,20H,9H2,1H3,(H,18,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	147	n/a	n/a	n/a	n/a	n/a	n/a
Martin-Luther University of Halle-Wittenberg Curated by ChEMBL					Assay Description Inhibition of recombinant human full length C-terminal His-tagged HDAC8 expressed in Escherichia coli BL21(DE3) using fluor de Lys(R) as substrate af...				J Med Chem 60: 10188-10204 (2017) Article DOI: 10.1021/acs.jmedchem.7b01447 BindingDB Entry DOI: 10.7270/Q2DZ0BQJ
					More data for this Ligand-Target Pair
Histone deacetylase 8 (Homo sapiens (Human))	BDBM50246849 (CHEMBL4080303) Show SMILES COc1ccc(cc1NCCc1ccccc1)C(=O)NO Show InChI InChI=1S/C16H18N2O3/c1-21-15-8-7-13(16(19)18-20)11-14(15)17-10-9-12-5-3-2-4-6-12/h2-8,11,17,20H,9-10H2,1H3,(H,18,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	151	n/a	n/a	n/a	n/a	n/a	n/a
Martin-Luther University of Halle-Wittenberg Curated by ChEMBL					Assay Description Inhibition of recombinant human full length C-terminal His-tagged HDAC8 expressed in Escherichia coli BL21(DE3) using fluor de Lys(R) as substrate af...				J Med Chem 60: 10188-10204 (2017) Article DOI: 10.1021/acs.jmedchem.7b01447 BindingDB Entry DOI: 10.7270/Q2DZ0BQJ
					More data for this Ligand-Target Pair
Histone deacetylase 8 (Homo sapiens (Human))	BDBM50246853 (CHEMBL4097353) Show SMILES Cc1ccc(cc1NCc1ccc(Cl)cc1)C(=O)NO Show InChI InChI=1S/C15H15ClN2O2/c1-10-2-5-12(15(19)18-20)8-14(10)17-9-11-3-6-13(16)7-4-11/h2-8,17,20H,9H2,1H3,(H,18,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	161	n/a	n/a	n/a	n/a	n/a	n/a
Martin-Luther University of Halle-Wittenberg Curated by ChEMBL					Assay Description Inhibition of recombinant human full length C-terminal His-tagged HDAC8 expressed in Escherichia coli BL21(DE3) using fluor de Lys(R) as substrate af...				J Med Chem 60: 10188-10204 (2017) Article DOI: 10.1021/acs.jmedchem.7b01447 BindingDB Entry DOI: 10.7270/Q2DZ0BQJ
					More data for this Ligand-Target Pair
Histone deacetylase 8 (Homo sapiens (Human))	BDBM50246871 (CHEMBL4068505) Show SMILES COc1cccc(CNc2cc(ccc2OC)C(=O)NO)c1 Show InChI InChI=1S/C16H18N2O4/c1-21-13-5-3-4-11(8-13)10-17-14-9-12(16(19)18-20)6-7-15(14)22-2/h3-9,17,20H,10H2,1-2H3,(H,18,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	167	n/a	n/a	n/a	n/a	n/a	n/a
Martin-Luther University of Halle-Wittenberg Curated by ChEMBL					Assay Description Inhibition of recombinant human full length C-terminal His-tagged HDAC8 expressed in Escherichia coli BL21(DE3) using fluor de Lys(R) as substrate af...				J Med Chem 60: 10188-10204 (2017) Article DOI: 10.1021/acs.jmedchem.7b01447 BindingDB Entry DOI: 10.7270/Q2DZ0BQJ
					More data for this Ligand-Target Pair
Histone deacetylase 8 (Homo sapiens (Human))	BDBM50246863 (CHEMBL4093480) Show SMILES ONC(=O)c1ccc(Cl)c(c1)C(=O)Nc1ccc(Cl)cc1 Show InChI InChI=1S/C14H10Cl2N2O3/c15-9-2-4-10(5-3-9)17-14(20)11-7-8(13(19)18-21)1-6-12(11)16/h1-7,21H,(H,17,20)(H,18,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	175	n/a	n/a	n/a	n/a	n/a	n/a
Martin-Luther University of Halle-Wittenberg Curated by ChEMBL					Assay Description Inhibition of recombinant human full length C-terminal His-tagged HDAC8 expressed in Escherichia coli BL21(DE3) using fluor de Lys(R) as substrate af...				J Med Chem 60: 10188-10204 (2017) Article DOI: 10.1021/acs.jmedchem.7b01447 BindingDB Entry DOI: 10.7270/Q2DZ0BQJ
					More data for this Ligand-Target Pair
Histone deacetylase 8 (Homo sapiens (Human))	BDBM50246851 (CHEMBL4074491) Show SMILES COc1ccc(cc1OCc1ccc(Cl)cc1)C(=O)NO Show InChI InChI=1S/C15H14ClNO4/c1-20-13-7-4-11(15(18)17-19)8-14(13)21-9-10-2-5-12(16)6-3-10/h2-8,19H,9H2,1H3,(H,17,18)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	181	n/a	n/a	n/a	n/a	n/a	n/a
Martin-Luther University of Halle-Wittenberg Curated by ChEMBL					Assay Description Inhibition of recombinant human full length C-terminal His-tagged HDAC8 expressed in Escherichia coli BL21(DE3) using fluor de Lys(R) as substrate af...				J Med Chem 60: 10188-10204 (2017) Article DOI: 10.1021/acs.jmedchem.7b01447 BindingDB Entry DOI: 10.7270/Q2DZ0BQJ
					More data for this Ligand-Target Pair
Histone deacetylase 8 (Homo sapiens (Human))	BDBM50246855 (CHEMBL4081759) Show SMILES COc1ccc(cc1NCc1cccc(Oc2ccccc2)c1)C(=O)NO Show InChI InChI=1S/C21H20N2O4/c1-26-20-11-10-16(21(24)23-25)13-19(20)22-14-15-6-5-9-18(12-15)27-17-7-3-2-4-8-17/h2-13,22,25H,14H2,1H3,(H,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	202	n/a	n/a	n/a	n/a	n/a	n/a
Martin-Luther University of Halle-Wittenberg Curated by ChEMBL					Assay Description Inhibition of recombinant human full length C-terminal His-tagged HDAC8 expressed in Escherichia coli BL21(DE3) using fluor de Lys(R) as substrate af...				J Med Chem 60: 10188-10204 (2017) Article DOI: 10.1021/acs.jmedchem.7b01447 BindingDB Entry DOI: 10.7270/Q2DZ0BQJ
					More data for this Ligand-Target Pair
Histone deacetylase 8 (Homo sapiens (Human))	BDBM50246860 (CHEMBL4075725) Show SMILES Cc1ccc(cc1NCc1ccc(cc1)-c1ccccc1)C(=O)NO Show InChI InChI=1S/C21H20N2O2/c1-15-7-10-19(21(24)23-25)13-20(15)22-14-16-8-11-18(12-9-16)17-5-3-2-4-6-17/h2-13,22,25H,14H2,1H3,(H,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	227	n/a	n/a	n/a	n/a	n/a	n/a
Martin-Luther University of Halle-Wittenberg Curated by ChEMBL					Assay Description Inhibition of recombinant human full length C-terminal His-tagged HDAC8 expressed in Escherichia coli BL21(DE3) using fluor de Lys(R) as substrate af...				J Med Chem 60: 10188-10204 (2017) Article DOI: 10.1021/acs.jmedchem.7b01447 BindingDB Entry DOI: 10.7270/Q2DZ0BQJ
					More data for this Ligand-Target Pair
Histone deacetylase 8 (Homo sapiens (Human))	BDBM50246857 (CHEMBL4073344) Show SMILES COc1ccc(cc1NC(C)c1ccc(Cl)cc1)C(=O)NO Show InChI InChI=1S/C16H17ClN2O3/c1-10(11-3-6-13(17)7-4-11)18-14-9-12(16(20)19-21)5-8-15(14)22-2/h3-10,18,21H,1-2H3,(H,19,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	240	n/a	n/a	n/a	n/a	n/a	n/a
Martin-Luther University of Halle-Wittenberg Curated by ChEMBL					Assay Description Inhibition of recombinant human full length C-terminal His-tagged HDAC8 expressed in Escherichia coli BL21(DE3) using fluor de Lys(R) as substrate af...				J Med Chem 60: 10188-10204 (2017) Article DOI: 10.1021/acs.jmedchem.7b01447 BindingDB Entry DOI: 10.7270/Q2DZ0BQJ
					More data for this Ligand-Target Pair
Histone deacetylase 8 (Homo sapiens (Human))	BDBM50246850 (CHEMBL4099064) Show SMILES Cc1ccc(cc1NCCCc1ccccc1)C(=O)NO Show InChI InChI=1S/C17H20N2O2/c1-13-9-10-15(17(20)19-21)12-16(13)18-11-5-8-14-6-3-2-4-7-14/h2-4,6-7,9-10,12,18,21H,5,8,11H2,1H3,(H,19,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	248	n/a	n/a	n/a	n/a	n/a	n/a
Martin-Luther University of Halle-Wittenberg Curated by ChEMBL					Assay Description Inhibition of recombinant human full length C-terminal His-tagged HDAC8 expressed in Escherichia coli BL21(DE3) using fluor de Lys(R) as substrate af...				J Med Chem 60: 10188-10204 (2017) Article DOI: 10.1021/acs.jmedchem.7b01447 BindingDB Entry DOI: 10.7270/Q2DZ0BQJ
					More data for this Ligand-Target Pair
Histone deacetylase 8 (Homo sapiens (Human))	BDBM50246859 (CHEMBL4066734) Show SMILES ONC(=O)c1ccc(Cl)c(NCc2ccccc2)c1 Show InChI InChI=1S/C14H13ClN2O2/c15-12-7-6-11(14(18)17-19)8-13(12)16-9-10-4-2-1-3-5-10/h1-8,16,19H,9H2,(H,17,18)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	254	n/a	n/a	n/a	n/a	n/a	n/a
Martin-Luther University of Halle-Wittenberg Curated by ChEMBL					Assay Description Inhibition of recombinant human full length C-terminal His-tagged HDAC8 expressed in Escherichia coli BL21(DE3) using fluor de Lys(R) as substrate af...				J Med Chem 60: 10188-10204 (2017) Article DOI: 10.1021/acs.jmedchem.7b01447 BindingDB Entry DOI: 10.7270/Q2DZ0BQJ
					More data for this Ligand-Target Pair
Histone deacetylase 8 (Homo sapiens (Human))	BDBM50246852 (CHEMBL4101727) Show SMILES Cc1ccc(cc1NCc1ccccc1)C(=O)NO Show InChI InChI=1S/C15H16N2O2/c1-11-7-8-13(15(18)17-19)9-14(11)16-10-12-5-3-2-4-6-12/h2-9,16,19H,10H2,1H3,(H,17,18)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	260	n/a	n/a	n/a	n/a	n/a	n/a
Martin-Luther University of Halle-Wittenberg Curated by ChEMBL					Assay Description Inhibition of recombinant human full length C-terminal His-tagged HDAC8 expressed in Escherichia coli BL21(DE3) using fluor de Lys(R) as substrate af...				J Med Chem 60: 10188-10204 (2017) Article DOI: 10.1021/acs.jmedchem.7b01447 BindingDB Entry DOI: 10.7270/Q2DZ0BQJ
					More data for this Ligand-Target Pair
Histone deacetylase 8 (Homo sapiens (Human))	BDBM50246870 (CHEMBL4087210) Show SMILES Cc1ccc(cc1NCc1ccccc1Cl)C(=O)NO Show InChI InChI=1S/C15H15ClN2O2/c1-10-6-7-11(15(19)18-20)8-14(10)17-9-12-4-2-3-5-13(12)16/h2-8,17,20H,9H2,1H3,(H,18,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	286	n/a	n/a	n/a	n/a	n/a	n/a
Martin-Luther University of Halle-Wittenberg Curated by ChEMBL					Assay Description Inhibition of recombinant human full length C-terminal His-tagged HDAC8 expressed in Escherichia coli BL21(DE3) using fluor de Lys(R) as substrate af...				J Med Chem 60: 10188-10204 (2017) Article DOI: 10.1021/acs.jmedchem.7b01447 BindingDB Entry DOI: 10.7270/Q2DZ0BQJ
					More data for this Ligand-Target Pair
Histone deacetylase 8 (Homo sapiens (Human))	BDBM50246854 (CHEMBL4079328) Show SMILES Cc1ccc(cc1NCc1c(Cl)cccc1Cl)C(=O)NO Show InChI InChI=1S/C15H14Cl2N2O2/c1-9-5-6-10(15(20)19-21)7-14(9)18-8-11-12(16)3-2-4-13(11)17/h2-7,18,21H,8H2,1H3,(H,19,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	335	n/a	n/a	n/a	n/a	n/a	n/a
Martin-Luther University of Halle-Wittenberg Curated by ChEMBL					Assay Description Inhibition of recombinant human full length C-terminal His-tagged HDAC8 expressed in Escherichia coli BL21(DE3) using fluor de Lys(R) as substrate af...				J Med Chem 60: 10188-10204 (2017) Article DOI: 10.1021/acs.jmedchem.7b01447 BindingDB Entry DOI: 10.7270/Q2DZ0BQJ
					More data for this Ligand-Target Pair
Histone deacetylase 8 (Homo sapiens (Human))	BDBM50246856 (CHEMBL4059841) Show SMILES COc1ccc(cc1NCc1ccc2ccccc2n1)C(=O)NO Show InChI InChI=1S/C18H17N3O3/c1-24-17-9-7-13(18(22)21-23)10-16(17)19-11-14-8-6-12-4-2-3-5-15(12)20-14/h2-10,19,23H,11H2,1H3,(H,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	481	n/a	n/a	n/a	n/a	n/a	n/a
Martin-Luther University of Halle-Wittenberg Curated by ChEMBL					Assay Description Inhibition of recombinant human full length C-terminal His-tagged HDAC8 expressed in Escherichia coli BL21(DE3) using fluor de Lys(R) as substrate af...				J Med Chem 60: 10188-10204 (2017) Article DOI: 10.1021/acs.jmedchem.7b01447 BindingDB Entry DOI: 10.7270/Q2DZ0BQJ
					More data for this Ligand-Target Pair
Histone deacetylase 8 (Homo sapiens (Human))	BDBM50372468 (CHEMBL406800 | SB-379278A) Show SMILES S=c1[nH]cc([nH]1)-c1ccncc1 Show InChI InChI=1S/C8H7N3S/c12-8-10-5-7(11-8)6-1-3-9-4-2-6/h1-5H,(H2,10,11,12)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
Martin-Luther University of Halle-Wittenberg Curated by ChEMBL					Assay Description Inhibition of HDAC8 (unknown origin) by HTS assay				J Med Chem 60: 10188-10204 (2017) Article DOI: 10.1021/acs.jmedchem.7b01447 BindingDB Entry DOI: 10.7270/Q2DZ0BQJ
					More data for this Ligand-Target Pair
Histone deacetylase 8 (Homo sapiens (Human))	BDBM50246867 (CHEMBL4095909) Show SMILES COc1ccc(cc1OCc1ccc(Cl)cc1Cl)C(=O)NO Show InChI InChI=1S/C15H13Cl2NO4/c1-21-13-5-3-9(15(19)18-20)6-14(13)22-8-10-2-4-11(16)7-12(10)17/h2-7,20H,8H2,1H3,(H,18,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	840	n/a	n/a	n/a	n/a	n/a	n/a
Martin-Luther University of Halle-Wittenberg Curated by ChEMBL					Assay Description Inhibition of recombinant human full length C-terminal His-tagged HDAC8 expressed in Escherichia coli BL21(DE3) using fluor de Lys(R) as substrate af...				J Med Chem 60: 10188-10204 (2017) Article DOI: 10.1021/acs.jmedchem.7b01447 BindingDB Entry DOI: 10.7270/Q2DZ0BQJ
					More data for this Ligand-Target Pair
Histone deacetylase 8 (Homo sapiens (Human))	BDBM50246875 (CHEMBL4085740) Show SMILES ONC(=O)c1ccc(Cl)c(OCc2ccc(Cl)cc2)c1 Show InChI InChI=1S/C14H11Cl2NO3/c15-11-4-1-9(2-5-11)8-20-13-7-10(14(18)17-19)3-6-12(13)16/h1-7,19H,8H2,(H,17,18)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.02E+3	n/a	n/a	n/a	n/a	n/a	n/a
Martin-Luther University of Halle-Wittenberg Curated by ChEMBL					Assay Description Inhibition of recombinant human full length C-terminal His-tagged HDAC8 expressed in Escherichia coli BL21(DE3) using fluor de Lys(R) as substrate af...				J Med Chem 60: 10188-10204 (2017) Article DOI: 10.1021/acs.jmedchem.7b01447 BindingDB Entry DOI: 10.7270/Q2DZ0BQJ
					More data for this Ligand-Target Pair
Histone deacetylase 8 (Homo sapiens (Human))	BDBM50246868 (CHEMBL4103665) Show SMILES ONC(=O)c1ccc(Cl)c(OCc2ccccc2Cl)c1 Show InChI InChI=1S/C14H11Cl2NO3/c15-11-4-2-1-3-10(11)8-20-13-7-9(14(18)17-19)5-6-12(13)16/h1-7,19H,8H2,(H,17,18)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Martin-Luther University of Halle-Wittenberg Curated by ChEMBL					Assay Description Inhibition of recombinant human full length C-terminal His-tagged HDAC8 expressed in Escherichia coli BL21(DE3) using fluor de Lys(R) as substrate af...				J Med Chem 60: 10188-10204 (2017) Article DOI: 10.1021/acs.jmedchem.7b01447 BindingDB Entry DOI: 10.7270/Q2DZ0BQJ
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM50164532 (CHEMBL3797516) Show SMILES COc1ccc(cc1OCc1ccccc1)C(=O)NO Show InChI InChI=1S/C15H15NO4/c1-19-13-8-7-12(15(17)16-18)9-14(13)20-10-11-5-3-2-4-6-11/h2-9,18H,10H2,1H3,(H,16,17)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Martin-Luther University of Halle-Wittenberg Curated by ChEMBL					Assay Description Inhibition of recombinant human full length HDAC6 expressed in fall armyworm Sf9 cells using fluorogenic ZMAL as substrate after 90 mins by fluorimet...				J Med Chem 60: 10188-10204 (2017) Article DOI: 10.1021/acs.jmedchem.7b01447 BindingDB Entry DOI: 10.7270/Q2DZ0BQJ
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM50246862 (CHEMBL2381520) Show SMILES ONC(=O)c1cccc(c1)C(=O)Nc1ccccc1 Show InChI InChI=1S/C14H12N2O3/c17-13(15-12-7-2-1-3-8-12)10-5-4-6-11(9-10)14(18)16-19/h1-9,19H,(H,15,17)(H,16,18)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	3.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Martin-Luther University of Halle-Wittenberg Curated by ChEMBL					Assay Description Inhibition of recombinant human full length HDAC6 expressed in fall armyworm Sf9 cells using fluorogenic ZMAL as substrate after 90 mins by fluorimet...				J Med Chem 60: 10188-10204 (2017) Article DOI: 10.1021/acs.jmedchem.7b01447 BindingDB Entry DOI: 10.7270/Q2DZ0BQJ
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM50246859 (CHEMBL4066734) Show SMILES ONC(=O)c1ccc(Cl)c(NCc2ccccc2)c1 Show InChI InChI=1S/C14H13ClN2O2/c15-12-7-6-11(14(18)17-19)8-13(12)16-9-10-4-2-1-3-5-10/h1-8,16,19H,9H2,(H,17,18)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Martin-Luther University of Halle-Wittenberg Curated by ChEMBL					Assay Description Inhibition of recombinant human full length HDAC6 expressed in fall armyworm Sf9 cells using fluorogenic ZMAL as substrate after 90 mins by fluorimet...				J Med Chem 60: 10188-10204 (2017) Article DOI: 10.1021/acs.jmedchem.7b01447 BindingDB Entry DOI: 10.7270/Q2DZ0BQJ
					More data for this Ligand-Target Pair
Histone deacetylase 8 (Homo sapiens (Human))	BDBM50246869 (CHEMBL4084319) Show SMILES ONC(=O)c1ccc(Cl)c(OCc2ccc(Cl)cc2Cl)c1 Show InChI InChI=1S/C14H10Cl3NO3/c15-10-3-1-9(12(17)6-10)7-21-13-5-8(14(19)18-20)2-4-11(13)16/h1-6,20H,7H2,(H,18,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.15E+3	n/a	n/a	n/a	n/a	n/a	n/a
Martin-Luther University of Halle-Wittenberg Curated by ChEMBL					Assay Description Inhibition of recombinant human full length C-terminal His-tagged HDAC8 expressed in Escherichia coli BL21(DE3) using fluor de Lys(R) as substrate af...				J Med Chem 60: 10188-10204 (2017) Article DOI: 10.1021/acs.jmedchem.7b01447 BindingDB Entry DOI: 10.7270/Q2DZ0BQJ
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM50246851 (CHEMBL4074491) Show SMILES COc1ccc(cc1OCc1ccc(Cl)cc1)C(=O)NO Show InChI InChI=1S/C15H14ClNO4/c1-20-13-7-4-11(15(18)17-19)8-14(13)21-9-10-2-5-12(16)6-3-10/h2-8,19H,9H2,1H3,(H,17,18)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Martin-Luther University of Halle-Wittenberg Curated by ChEMBL					Assay Description Inhibition of recombinant human full length HDAC6 expressed in fall armyworm Sf9 cells using fluorogenic ZMAL as substrate after 90 mins by fluorimet...				J Med Chem 60: 10188-10204 (2017) Article DOI: 10.1021/acs.jmedchem.7b01447 BindingDB Entry DOI: 10.7270/Q2DZ0BQJ
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM50246848 (CHEMBL4061831) Show SMILES ONC(=O)c1ccc(F)c(NCc2ccccc2)c1 Show InChI InChI=1S/C14H13FN2O2/c15-12-7-6-11(14(18)17-19)8-13(12)16-9-10-4-2-1-3-5-10/h1-8,16,19H,9H2,(H,17,18)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Martin-Luther University of Halle-Wittenberg Curated by ChEMBL					Assay Description Inhibition of recombinant human full length HDAC6 expressed in fall armyworm Sf9 cells using fluorogenic ZMAL as substrate after 90 mins by fluorimet...				J Med Chem 60: 10188-10204 (2017) Article DOI: 10.1021/acs.jmedchem.7b01447 BindingDB Entry DOI: 10.7270/Q2DZ0BQJ
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM50246852 (CHEMBL4101727) Show SMILES Cc1ccc(cc1NCc1ccccc1)C(=O)NO Show InChI InChI=1S/C15H16N2O2/c1-11-7-8-13(15(18)17-19)9-14(11)16-10-12-5-3-2-4-6-12/h2-9,16,19H,10H2,1H3,(H,17,18)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	5.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Martin-Luther University of Halle-Wittenberg Curated by ChEMBL					Assay Description Inhibition of recombinant human full length HDAC6 expressed in fall armyworm Sf9 cells using fluorogenic ZMAL as substrate after 90 mins by fluorimet...				J Med Chem 60: 10188-10204 (2017) Article DOI: 10.1021/acs.jmedchem.7b01447 BindingDB Entry DOI: 10.7270/Q2DZ0BQJ
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM50246846 (CHEMBL4105068) Show SMILES COc1ccc(cc1NCc1ccccc1)C(=O)NO Show InChI InChI=1S/C15H16N2O3/c1-20-14-8-7-12(15(18)17-19)9-13(14)16-10-11-5-3-2-4-6-11/h2-9,16,19H,10H2,1H3,(H,17,18)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Martin-Luther University of Halle-Wittenberg Curated by ChEMBL					Assay Description Inhibition of recombinant human full length HDAC6 expressed in fall armyworm Sf9 cells using fluorogenic ZMAL as substrate after 90 mins by fluorimet...				J Med Chem 60: 10188-10204 (2017) Article DOI: 10.1021/acs.jmedchem.7b01447 BindingDB Entry DOI: 10.7270/Q2DZ0BQJ
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM50246849 (CHEMBL4080303) Show SMILES COc1ccc(cc1NCCc1ccccc1)C(=O)NO Show InChI InChI=1S/C16H18N2O3/c1-21-15-8-7-13(16(19)18-20)11-14(15)17-10-9-12-5-3-2-4-6-12/h2-8,11,17,20H,9-10H2,1H3,(H,18,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Martin-Luther University of Halle-Wittenberg Curated by ChEMBL					Assay Description Inhibition of recombinant human full length HDAC6 expressed in fall armyworm Sf9 cells using fluorogenic ZMAL as substrate after 90 mins by fluorimet...				J Med Chem 60: 10188-10204 (2017) Article DOI: 10.1021/acs.jmedchem.7b01447 BindingDB Entry DOI: 10.7270/Q2DZ0BQJ
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM50246850 (CHEMBL4099064) Show SMILES Cc1ccc(cc1NCCCc1ccccc1)C(=O)NO Show InChI InChI=1S/C17H20N2O2/c1-13-9-10-15(17(20)19-21)12-16(13)18-11-5-8-14-6-3-2-4-7-14/h2-4,6-7,9-10,12,18,21H,5,8,11H2,1H3,(H,19,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
Martin-Luther University of Halle-Wittenberg Curated by ChEMBL					Assay Description Inhibition of recombinant human full length HDAC6 expressed in fall armyworm Sf9 cells using fluorogenic ZMAL as substrate after 90 mins by fluorimet...				J Med Chem 60: 10188-10204 (2017) Article DOI: 10.1021/acs.jmedchem.7b01447 BindingDB Entry DOI: 10.7270/Q2DZ0BQJ
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50246859 (CHEMBL4066734) Show SMILES ONC(=O)c1ccc(Cl)c(NCc2ccccc2)c1 Show InChI InChI=1S/C14H13ClN2O2/c15-12-7-6-11(14(18)17-19)8-13(12)16-9-10-4-2-1-3-5-10/h1-8,16,19H,9H2,(H,17,18)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.04E+4	n/a	n/a	n/a	n/a	n/a	n/a
Martin-Luther University of Halle-Wittenberg Curated by ChEMBL					Assay Description Inhibition of recombinant human full length C-terminal FLAG-tagged HDAC1 expressed in fall armyworm Sf9 cells using fluorogenic ZMAL as substrate aft...				J Med Chem 60: 10188-10204 (2017) Article DOI: 10.1021/acs.jmedchem.7b01447 BindingDB Entry DOI: 10.7270/Q2DZ0BQJ
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50164532 (CHEMBL3797516) Show SMILES COc1ccc(cc1OCc1ccccc1)C(=O)NO Show InChI InChI=1S/C15H15NO4/c1-19-13-8-7-12(15(17)16-18)9-14(13)20-10-11-5-3-2-4-6-11/h2-9,18H,10H2,1H3,(H,16,17)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.21E+4	n/a	n/a	n/a	n/a	n/a	n/a
Martin-Luther University of Halle-Wittenberg Curated by ChEMBL					Assay Description Inhibition of recombinant human full length C-terminal FLAG-tagged HDAC1 expressed in fall armyworm Sf9 cells using fluorogenic ZMAL as substrate aft...				J Med Chem 60: 10188-10204 (2017) Article DOI: 10.1021/acs.jmedchem.7b01447 BindingDB Entry DOI: 10.7270/Q2DZ0BQJ
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM50246847 (CHEMBL4089635) Show SMILES Cc1ccc(cc1NCc1ccc(Cl)cc1Cl)C(=O)NO Show InChI InChI=1S/C15H14Cl2N2O2/c1-9-2-3-10(15(20)19-21)6-14(9)18-8-11-4-5-12(16)7-13(11)17/h2-7,18,21H,8H2,1H3,(H,19,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.44E+4	n/a	n/a	n/a	n/a	n/a	n/a
Martin-Luther University of Halle-Wittenberg Curated by ChEMBL					Assay Description Inhibition of recombinant human full length HDAC6 expressed in fall armyworm Sf9 cells using fluorogenic ZMAL as substrate after 90 mins by fluorimet...				J Med Chem 60: 10188-10204 (2017) Article DOI: 10.1021/acs.jmedchem.7b01447 BindingDB Entry DOI: 10.7270/Q2DZ0BQJ
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50246851 (CHEMBL4074491) Show SMILES COc1ccc(cc1OCc1ccc(Cl)cc1)C(=O)NO Show InChI InChI=1S/C15H14ClNO4/c1-20-13-7-4-11(15(18)17-19)8-14(13)21-9-10-2-5-12(16)6-3-10/h2-8,19H,9H2,1H3,(H,17,18)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.45E+4	n/a	n/a	n/a	n/a	n/a	n/a
Martin-Luther University of Halle-Wittenberg Curated by ChEMBL					Assay Description Inhibition of recombinant human full length C-terminal FLAG-tagged HDAC1 expressed in fall armyworm Sf9 cells using fluorogenic ZMAL as substrate aft...				J Med Chem 60: 10188-10204 (2017) Article DOI: 10.1021/acs.jmedchem.7b01447 BindingDB Entry DOI: 10.7270/Q2DZ0BQJ
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50246846 (CHEMBL4105068) Show SMILES COc1ccc(cc1NCc1ccccc1)C(=O)NO Show InChI InChI=1S/C15H16N2O3/c1-20-14-8-7-12(15(18)17-19)9-13(14)16-10-11-5-3-2-4-6-11/h2-9,16,19H,10H2,1H3,(H,17,18)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.45E+4	n/a	n/a	n/a	n/a	n/a	n/a
Martin-Luther University of Halle-Wittenberg Curated by ChEMBL					Assay Description Inhibition of recombinant human full length C-terminal FLAG-tagged HDAC1 expressed in fall armyworm Sf9 cells using fluorogenic ZMAL as substrate aft...				J Med Chem 60: 10188-10204 (2017) Article DOI: 10.1021/acs.jmedchem.7b01447 BindingDB Entry DOI: 10.7270/Q2DZ0BQJ
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50246847 (CHEMBL4089635) Show SMILES Cc1ccc(cc1NCc1ccc(Cl)cc1Cl)C(=O)NO Show InChI InChI=1S/C15H14Cl2N2O2/c1-9-2-3-10(15(20)19-21)6-14(9)18-8-11-4-5-12(16)7-13(11)17/h2-7,18,21H,8H2,1H3,(H,19,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.87E+4	n/a	n/a	n/a	n/a	n/a	n/a
Martin-Luther University of Halle-Wittenberg Curated by ChEMBL					Assay Description Inhibition of recombinant human full length C-terminal FLAG-tagged HDAC1 expressed in fall armyworm Sf9 cells using fluorogenic ZMAL as substrate aft...				J Med Chem 60: 10188-10204 (2017) Article DOI: 10.1021/acs.jmedchem.7b01447 BindingDB Entry DOI: 10.7270/Q2DZ0BQJ
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50246849 (CHEMBL4080303) Show SMILES COc1ccc(cc1NCCc1ccccc1)C(=O)NO Show InChI InChI=1S/C16H18N2O3/c1-21-15-8-7-13(16(19)18-20)11-14(15)17-10-9-12-5-3-2-4-6-12/h2-8,11,17,20H,9-10H2,1H3,(H,18,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.91E+4	n/a	n/a	n/a	n/a	n/a	n/a
Martin-Luther University of Halle-Wittenberg Curated by ChEMBL					Assay Description Inhibition of recombinant human full length C-terminal FLAG-tagged HDAC1 expressed in fall armyworm Sf9 cells using fluorogenic ZMAL as substrate aft...				J Med Chem 60: 10188-10204 (2017) Article DOI: 10.1021/acs.jmedchem.7b01447 BindingDB Entry DOI: 10.7270/Q2DZ0BQJ
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50246852 (CHEMBL4101727) Show SMILES Cc1ccc(cc1NCc1ccccc1)C(=O)NO Show InChI InChI=1S/C15H16N2O2/c1-11-7-8-13(15(18)17-19)9-14(11)16-10-12-5-3-2-4-6-12/h2-9,16,19H,10H2,1H3,(H,17,18)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	2.18E+4	n/a	n/a	n/a	n/a	n/a	n/a
Martin-Luther University of Halle-Wittenberg Curated by ChEMBL					Assay Description Inhibition of recombinant human full length C-terminal FLAG-tagged HDAC1 expressed in fall armyworm Sf9 cells using fluorogenic ZMAL as substrate aft...				J Med Chem 60: 10188-10204 (2017) Article DOI: 10.1021/acs.jmedchem.7b01447 BindingDB Entry DOI: 10.7270/Q2DZ0BQJ
					More data for this Ligand-Target Pair

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