Found 15 hits Enz. Inhib. hit(s) with all data for entry = 50040916 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Kappa-type opioid receptor
(Mus musculus (Mouse)) | BDBM50402138
(CHEMBL2207678)Show InChI InChI=1S/C22H27NO2/c24-17-5-3-15-10-22-11-16-4-6-20(22)23(13-14-1-2-14)8-7-21(22,12-19(16)25)18(15)9-17/h3,5,9,14,16,20,24H,1-2,4,6-8,10-13H2 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 0.840 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]U-69,593 from kappa opioid receptor in mouse whole brain without cerebellum |
Bioorg Med Chem Lett 22: 7697-701 (2012)
Article DOI: 10.1016/j.bmcl.2012.09.102
BindingDB Entry DOI: 10.7270/Q2DN466K |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Mus musculus (Mouse)) | BDBM50402139
(CHEMBL2207679)Show SMILES Oc1ccc2CC34CC5C=CC3N(CC3CC3)CCC4(CC5=O)c2c1 |c:9| Show InChI InChI=1S/C22H25NO2/c24-17-5-3-15-10-22-11-16-4-6-20(22)23(13-14-1-2-14)8-7-21(22,12-19(16)25)18(15)9-17/h3-6,9,14,16,20,24H,1-2,7-8,10-13H2 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| 1.92 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]U-69,593 from kappa opioid receptor in mouse whole brain without cerebellum |
Bioorg Med Chem Lett 22: 7697-701 (2012)
Article DOI: 10.1016/j.bmcl.2012.09.102
BindingDB Entry DOI: 10.7270/Q2DN466K |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(GUINEA PIG) | BDBM50402138
(CHEMBL2207678)Show InChI InChI=1S/C22H27NO2/c24-17-5-3-15-10-22-11-16-4-6-20(22)23(13-14-1-2-14)8-7-21(22,12-19(16)25)18(15)9-17/h3,5,9,14,16,20,24H,1-2,4,6-8,10-13H2 | PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 3.21 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]DAMGO from mu opioid receptor in guinea pig cerebellum |
Bioorg Med Chem Lett 22: 7697-701 (2012)
Article DOI: 10.1016/j.bmcl.2012.09.102
BindingDB Entry DOI: 10.7270/Q2DN466K |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Mus musculus (Mouse)) | BDBM50402140
(CHEMBL2207680)Show SMILES O[C@@H]1CC2N(CC3CC3)CCC34CC(=O)C1CC23Cc1ccc(O)cc41 |r| Show InChI InChI=1S/C22H27NO3/c24-15-4-3-14-9-22-10-16-18(25)8-20(22)23(12-13-1-2-13)6-5-21(22,11-19(16)26)17(14)7-15/h3-4,7,13,16,18,20,24-25H,1-2,5-6,8-12H2/t16?,18-,20?,21?,22?/m1/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 7.63 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]U-69,593 from kappa opioid receptor in mouse whole brain without cerebellum |
Bioorg Med Chem Lett 22: 7697-701 (2012)
Article DOI: 10.1016/j.bmcl.2012.09.102
BindingDB Entry DOI: 10.7270/Q2DN466K |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(GUINEA PIG) | BDBM50402140
(CHEMBL2207680)Show SMILES O[C@@H]1CC2N(CC3CC3)CCC34CC(=O)C1CC23Cc1ccc(O)cc41 |r| Show InChI InChI=1S/C22H27NO3/c24-15-4-3-14-9-22-10-16-18(25)8-20(22)23(12-13-1-2-13)6-5-21(22,11-19(16)26)17(14)7-15/h3-4,7,13,16,18,20,24-25H,1-2,5-6,8-12H2/t16?,18-,20?,21?,22?/m1/s1 | PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 13.1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]DAMGO from mu opioid receptor in guinea pig cerebellum |
Bioorg Med Chem Lett 22: 7697-701 (2012)
Article DOI: 10.1016/j.bmcl.2012.09.102
BindingDB Entry DOI: 10.7270/Q2DN466K |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Mus musculus (Mouse)) | BDBM50402141
(CHEMBL2207681)Show SMILES O[C@H]1CC2N(CC3CC3)CCC34CC(=O)C1CC23Cc1ccc(O)cc41 |r| Show InChI InChI=1S/C22H27NO3/c24-15-4-3-14-9-22-10-16-18(25)8-20(22)23(12-13-1-2-13)6-5-21(22,11-19(16)26)17(14)7-15/h3-4,7,13,16,18,20,24-25H,1-2,5-6,8-12H2/t16?,18-,20?,21?,22?/m0/s1 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 16.7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]U-69,593 from kappa opioid receptor in mouse whole brain without cerebellum |
Bioorg Med Chem Lett 22: 7697-701 (2012)
Article DOI: 10.1016/j.bmcl.2012.09.102
BindingDB Entry DOI: 10.7270/Q2DN466K |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(GUINEA PIG) | BDBM50402139
(CHEMBL2207679)Show SMILES Oc1ccc2CC34CC5C=CC3N(CC3CC3)CCC4(CC5=O)c2c1 |c:9| Show InChI InChI=1S/C22H25NO2/c24-17-5-3-15-10-22-11-16-4-6-20(22)23(13-14-1-2-14)8-7-21(22,12-19(16)25)18(15)9-17/h3-6,9,14,16,20,24H,1-2,7-8,10-13H2 | PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| 17.6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]DAMGO from mu opioid receptor in guinea pig cerebellum |
Bioorg Med Chem Lett 22: 7697-701 (2012)
Article DOI: 10.1016/j.bmcl.2012.09.102
BindingDB Entry DOI: 10.7270/Q2DN466K |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(MOUSE) | BDBM50402138
(CHEMBL2207678)Show InChI InChI=1S/C22H27NO2/c24-17-5-3-15-10-22-11-16-4-6-20(22)23(13-14-1-2-14)8-7-21(22,12-19(16)25)18(15)9-17/h3,5,9,14,16,20,24H,1-2,4,6-8,10-13H2 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 43.6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]DHDPE from delta opioid receptor in mouse whole brain without cerebellum |
Bioorg Med Chem Lett 22: 7697-701 (2012)
Article DOI: 10.1016/j.bmcl.2012.09.102
BindingDB Entry DOI: 10.7270/Q2DN466K |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(MOUSE) | BDBM50402139
(CHEMBL2207679)Show SMILES Oc1ccc2CC34CC5C=CC3N(CC3CC3)CCC4(CC5=O)c2c1 |c:9| Show InChI InChI=1S/C22H25NO2/c24-17-5-3-15-10-22-11-16-4-6-20(22)23(13-14-1-2-14)8-7-21(22,12-19(16)25)18(15)9-17/h3-6,9,14,16,20,24H,1-2,7-8,10-13H2 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
| Article
PubMed
| 52.2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]DHDPE from delta opioid receptor in mouse whole brain without cerebellum |
Bioorg Med Chem Lett 22: 7697-701 (2012)
Article DOI: 10.1016/j.bmcl.2012.09.102
BindingDB Entry DOI: 10.7270/Q2DN466K |
More data for this
Ligand-Target Pair | |
Kappa-type opioid receptor
(Mus musculus (Mouse)) | BDBM50402137
(CHEMBL2207677)Show SMILES Oc1ccc2CC34CC5C(=O)CC3N(CC3CC3)CCC4(CC5=O)c2c1 Show InChI InChI=1S/C22H25NO3/c24-15-4-3-14-9-22-10-16-18(25)8-20(22)23(12-13-1-2-13)6-5-21(22,11-19(16)26)17(14)7-15/h3-4,7,13,16,20,24H,1-2,5-6,8-12H2 | PDB
UniProtKB/SwissProt
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 56.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]U-69,593 from kappa opioid receptor in mouse whole brain without cerebellum |
Bioorg Med Chem Lett 22: 7697-701 (2012)
Article DOI: 10.1016/j.bmcl.2012.09.102
BindingDB Entry DOI: 10.7270/Q2DN466K |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(MOUSE) | BDBM50402140
(CHEMBL2207680)Show SMILES O[C@@H]1CC2N(CC3CC3)CCC34CC(=O)C1CC23Cc1ccc(O)cc41 |r| Show InChI InChI=1S/C22H27NO3/c24-15-4-3-14-9-22-10-16-18(25)8-20(22)23(12-13-1-2-13)6-5-21(22,11-19(16)26)17(14)7-15/h3-4,7,13,16,18,20,24-25H,1-2,5-6,8-12H2/t16?,18-,20?,21?,22?/m1/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 67.9 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]DHDPE from delta opioid receptor in mouse whole brain without cerebellum |
Bioorg Med Chem Lett 22: 7697-701 (2012)
Article DOI: 10.1016/j.bmcl.2012.09.102
BindingDB Entry DOI: 10.7270/Q2DN466K |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(GUINEA PIG) | BDBM50402141
(CHEMBL2207681)Show SMILES O[C@H]1CC2N(CC3CC3)CCC34CC(=O)C1CC23Cc1ccc(O)cc41 |r| Show InChI InChI=1S/C22H27NO3/c24-15-4-3-14-9-22-10-16-18(25)8-20(22)23(12-13-1-2-13)6-5-21(22,11-19(16)26)17(14)7-15/h3-4,7,13,16,18,20,24-25H,1-2,5-6,8-12H2/t16?,18-,20?,21?,22?/m0/s1 | PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 70.7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]DAMGO from mu opioid receptor in guinea pig cerebellum |
Bioorg Med Chem Lett 22: 7697-701 (2012)
Article DOI: 10.1016/j.bmcl.2012.09.102
BindingDB Entry DOI: 10.7270/Q2DN466K |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(MOUSE) | BDBM50402141
(CHEMBL2207681)Show SMILES O[C@H]1CC2N(CC3CC3)CCC34CC(=O)C1CC23Cc1ccc(O)cc41 |r| Show InChI InChI=1S/C22H27NO3/c24-15-4-3-14-9-22-10-16-18(25)8-20(22)23(12-13-1-2-13)6-5-21(22,11-19(16)26)17(14)7-15/h3-4,7,13,16,18,20,24-25H,1-2,5-6,8-12H2/t16?,18-,20?,21?,22?/m0/s1 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 146 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]DHDPE from delta opioid receptor in mouse whole brain without cerebellum |
Bioorg Med Chem Lett 22: 7697-701 (2012)
Article DOI: 10.1016/j.bmcl.2012.09.102
BindingDB Entry DOI: 10.7270/Q2DN466K |
More data for this
Ligand-Target Pair | |
Mu-type opioid receptor
(GUINEA PIG) | BDBM50402137
(CHEMBL2207677)Show SMILES Oc1ccc2CC34CC5C(=O)CC3N(CC3CC3)CCC4(CC5=O)c2c1 Show InChI InChI=1S/C22H25NO3/c24-15-4-3-14-9-22-10-16-18(25)8-20(22)23(12-13-1-2-13)6-5-21(22,11-19(16)26)17(14)7-15/h3-4,7,13,16,20,24H,1-2,5-6,8-12H2 | PDB
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 187 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]DAMGO from mu opioid receptor in guinea pig cerebellum |
Bioorg Med Chem Lett 22: 7697-701 (2012)
Article DOI: 10.1016/j.bmcl.2012.09.102
BindingDB Entry DOI: 10.7270/Q2DN466K |
More data for this
Ligand-Target Pair | |
Delta-type opioid receptor
(MOUSE) | BDBM50402137
(CHEMBL2207677)Show SMILES Oc1ccc2CC34CC5C(=O)CC3N(CC3CC3)CCC4(CC5=O)c2c1 Show InChI InChI=1S/C22H25NO3/c24-15-4-3-14-9-22-10-16-18(25)8-20(22)23(12-13-1-2-13)6-5-21(22,11-19(16)26)17(14)7-15/h3-4,7,13,16,20,24H,1-2,5-6,8-12H2 | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| 410 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Kitasato University
Curated by ChEMBL
| Assay Description
Displacement of [3H]DHDPE from delta opioid receptor in mouse whole brain without cerebellum |
Bioorg Med Chem Lett 22: 7697-701 (2012)
Article DOI: 10.1016/j.bmcl.2012.09.102
BindingDB Entry DOI: 10.7270/Q2DN466K |
More data for this
Ligand-Target Pair | |
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