Compile Data Set for Download or QSAR

Found 118 hits Enz. Inhib. hit(s) with all data for entry = 50003578   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM50006952 (2-{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-...) Show SMILES COc1ccccc1N1CCN(CCn2c(=O)[nH]c3c4ccccc4[nH]c3c2=O)CC1 Show InChI InChI=1S/C23H25N5O3/c1-31-19-9-5-4-8-18(19)27-13-10-26(11-14-27)12-15-28-22(29)21-20(25-23(28)30)16-6-2-3-7-17(16)24-21/h2-9,24H,10-15H2,1H3,(H,25,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.210	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Perugia Curated by ChEMBL					Assay Description Alpha-1-adrenergic receptor binding affinity of the compound, value taken from literature				J Med Chem 44: 2118-32 (2001) Article DOI: 10.1021/jm010821u BindingDB Entry DOI: 10.7270/Q2W3802N
					More data for this Ligand-Target Pair
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM29568 (CHEMBL2 | PRAZOSIN | PRAZOSIN HYDROCHLORIDE | [3H]...) Show SMILES COc1cc2nc(nc(N)c2cc1OC)N1CCN(CC1)C(=O)c1ccco1 Show InChI InChI=1S/C19H21N5O4/c1-26-15-10-12-13(11-16(15)27-2)21-19(22-17(12)20)24-7-5-23(6-8-24)18(25)14-4-3-9-28-14/h3-4,9-11H,5-8H2,1-2H3,(H2,20,21,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	0.240	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Perugia Curated by ChEMBL					Assay Description Binding affinity towards alpha-1 adrenergic receptor in rat cortex membrane using [3H]-prazosin radioligand				J Med Chem 44: 2118-32 (2001) Article DOI: 10.1021/jm010821u BindingDB Entry DOI: 10.7270/Q2W3802N
					More data for this Ligand-Target Pair
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM50473275 (CHEMBL305038) Show SMILES COc1ccccc1N1CCN(CCCCN2C(=O)CCc3ccccc23)CC1 Show InChI InChI=1S/C24H31N3O2/c1-29-23-11-5-4-10-22(23)26-18-16-25(17-19-26)14-6-7-15-27-21-9-3-2-8-20(21)12-13-24(27)28/h2-5,8-11H,6-7,12-19H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	0.340	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Perugia Curated by ChEMBL					Assay Description Alpha-1 adrenergic receptor binding affinity of the compound, value taken from literature				J Med Chem 44: 2118-32 (2001) Article DOI: 10.1021/jm010821u BindingDB Entry DOI: 10.7270/Q2W3802N
					More data for this Ligand-Target Pair
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM50473254 (CHEMBL66450) Show SMILES COc1ccccc1OCCN1CCN(CC1)c1ccc(=O)n(CCCCN2CCN(CC2)c2ccccc2OC)n1 Show InChI InChI=1S/C32H44N6O4/c1-40-28-10-4-3-9-27(28)36-21-17-34(18-22-36)15-7-8-16-38-32(39)14-13-31(33-38)37-23-19-35(20-24-37)25-26-42-30-12-6-5-11-29(30)41-2/h3-6,9-14H,7-8,15-26H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	0.600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Perugia Curated by ChEMBL					Assay Description Binding affinity towards alpha-1 adrenergic receptor in rat cortex membrane using [3H]-prazosin radioligand				J Med Chem 44: 2118-32 (2001) Article DOI: 10.1021/jm010821u BindingDB Entry DOI: 10.7270/Q2W3802N
					More data for this Ligand-Target Pair
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM29568 (CHEMBL2 | PRAZOSIN | PRAZOSIN HYDROCHLORIDE | [3H]...) Show SMILES COc1cc2nc(nc(N)c2cc1OC)N1CCN(CC1)C(=O)c1ccco1 Show InChI InChI=1S/C19H21N5O4/c1-26-15-10-12-13(11-16(15)27-2)21-19(22-17(12)20)24-7-5-23(6-8-24)18(25)14-4-3-9-28-14/h3-4,9-11H,5-8H2,1-2H3,(H2,20,21,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	0.740	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Perugia Curated by ChEMBL					Assay Description Alpha-1 adrenergic receptor binding affinity of the compound, value taken from literature				J Med Chem 44: 2118-32 (2001) Article DOI: 10.1021/jm010821u BindingDB Entry DOI: 10.7270/Q2W3802N
					More data for this Ligand-Target Pair
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM50473245 (CHEMBL68052) Show SMILES COc1ccccc1OCCN1CCN(CC1)c1ccc(=O)n(CCCCN2CCN(CC2)c2ccccc2Cl)n1 Show InChI InChI=1S/C31H41ClN6O3/c1-40-28-10-4-5-11-29(28)41-25-24-35-18-22-37(23-19-35)30-12-13-31(39)38(33-30)15-7-6-14-34-16-20-36(21-17-34)27-9-3-2-8-26(27)32/h2-5,8-13H,6-7,14-25H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	0.800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Perugia Curated by ChEMBL					Assay Description Binding affinity towards alpha-1 adrenergic receptor in rat cortex membrane using [3H]-prazosin radioligand				J Med Chem 44: 2118-32 (2001) Article DOI: 10.1021/jm010821u BindingDB Entry DOI: 10.7270/Q2W3802N
					More data for this Ligand-Target Pair
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM82517 (2-{4-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-butyl}-...) Show SMILES COc1ccccc1N1CCN(CCCCN2C(=O)c3ccccc3C2=O)CC1 Show InChI InChI=1S/C23H27N3O3/c1-29-21-11-5-4-10-20(21)25-16-14-24(15-17-25)12-6-7-13-26-22(27)18-8-2-3-9-19(18)23(26)28/h2-5,8-11H,6-7,12-17H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	0.800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Perugia Curated by ChEMBL					Assay Description Alpha-1 adrenergic receptor binding affinity of the compound, value taken from literature				J Med Chem 44: 2118-32 (2001) Article DOI: 10.1021/jm010821u BindingDB Entry DOI: 10.7270/Q2W3802N
					More data for this Ligand-Target Pair
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM50222012 (CHEMBL49152) Show SMILES COc1ccccc1OCCN1CCN(CC1)c1cnn(CCCCCCCN2CCN(CC2)c2ccccc2OC)c(=O)c1Cl Show InChI InChI=1S/C35H49ClN6O4/c1-44-31-13-7-6-12-29(31)40-22-18-38(19-23-40)16-10-4-3-5-11-17-42-35(43)34(36)30(28-37-42)41-24-20-39(21-25-41)26-27-46-33-15-9-8-14-32(33)45-2/h6-9,12-15,28H,3-5,10-11,16-27H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	1.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Perugia Curated by ChEMBL					Assay Description Binding affinity towards alpha-1 adrenergic receptor in rat cortex membrane using [3H]-prazosin radioligand				J Med Chem 44: 2118-32 (2001) Article DOI: 10.1021/jm010821u BindingDB Entry DOI: 10.7270/Q2W3802N
					More data for this Ligand-Target Pair
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM50473295 (CHEMBL66172) Show SMILES COc1ccccc1OCCN1CCN(CC1)c1cnn(CCCCCCN2CCN(CC2)c2ccccc2OC)c(=O)c1Cl Show InChI InChI=1S/C34H47ClN6O4/c1-43-30-12-6-5-11-28(30)39-21-17-37(18-22-39)15-9-3-4-10-16-41-34(42)33(35)29(27-36-41)40-23-19-38(20-24-40)25-26-45-32-14-8-7-13-31(32)44-2/h5-8,11-14,27H,3-4,9-10,15-26H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Perugia Curated by ChEMBL					Assay Description Binding affinity towards alpha-1 adrenergic receptor in rat cortex membrane using [3H]-prazosin radioligand				J Med Chem 44: 2118-32 (2001) Article DOI: 10.1021/jm010821u BindingDB Entry DOI: 10.7270/Q2W3802N
					More data for this Ligand-Target Pair
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM50222046 (CHEMBL46172) Show SMILES COc1ccccc1N1CCN(CCCCCCCn2ncc(N3CCN(CC3)C(=O)c3ccco3)c(Cl)c2=O)CC1 Show InChI InChI=1S/C31H41ClN6O4/c1-41-27-11-6-5-10-25(27)35-17-15-34(16-18-35)13-7-3-2-4-8-14-38-31(40)29(32)26(24-33-38)36-19-21-37(22-20-36)30(39)28-12-9-23-42-28/h5-6,9-12,23-24H,2-4,7-8,13-22H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	1.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Perugia Curated by ChEMBL					Assay Description Binding affinity towards alpha-1 adrenergic receptor in rat cortex membrane using [3H]-prazosin radioligand				J Med Chem 44: 2118-32 (2001) Article DOI: 10.1021/jm010821u BindingDB Entry DOI: 10.7270/Q2W3802N
					More data for this Ligand-Target Pair
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM50473261 (CHEMBL67201) Show SMILES COc1ccccc1N1CCN(CCCCCn2ncc(N3CCN(CC3)C(=O)c3ccco3)c(Cl)c2=O)CC1 Show InChI InChI=1S/C29H37ClN6O4/c1-39-25-9-4-3-8-23(25)33-15-13-32(14-16-33)11-5-2-6-12-36-29(38)27(30)24(22-31-36)34-17-19-35(20-18-34)28(37)26-10-7-21-40-26/h3-4,7-10,21-22H,2,5-6,11-20H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Perugia Curated by ChEMBL					Assay Description Binding affinity towards alpha-1 adrenergic receptor in rat cortex membrane using [3H]-prazosin radioligand				J Med Chem 44: 2118-32 (2001) Article DOI: 10.1021/jm010821u BindingDB Entry DOI: 10.7270/Q2W3802N
					More data for this Ligand-Target Pair
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM50473273 (CHEMBL302554) Show SMILES COc1ccccc1OCCN1CCN(CC1)c1ccc(=O)n(CCCCCCCN2CCN(CC2)c2ccccc2OC)n1 Show InChI InChI=1S/C35H50N6O4/c1-43-31-13-7-6-12-30(31)39-24-20-37(21-25-39)18-10-4-3-5-11-19-41-35(42)17-16-34(36-41)40-26-22-38(23-27-40)28-29-45-33-15-9-8-14-32(33)44-2/h6-9,12-17H,3-5,10-11,18-29H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Perugia Curated by ChEMBL					Assay Description Binding affinity towards alpha-1 adrenergic receptor in rat cortex membrane using [3H]-prazosin radioligand				J Med Chem 44: 2118-32 (2001) Article DOI: 10.1021/jm010821u BindingDB Entry DOI: 10.7270/Q2W3802N
					More data for this Ligand-Target Pair
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM50473265 (CHEMBL67132) Show SMILES COc1ccccc1OCCN1CCN(CC1)c1cnn(CCCCCCCN2CCN(CC2)c2ccccc2Cl)c(=O)c1Cl Show InChI InChI=1S/C34H46Cl2N6O3/c1-44-31-13-7-8-14-32(31)45-26-25-39-19-23-41(24-20-39)30-27-37-42(34(43)33(30)36)16-10-4-2-3-9-15-38-17-21-40(22-18-38)29-12-6-5-11-28(29)35/h5-8,11-14,27H,2-4,9-10,15-26H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	2.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Perugia Curated by ChEMBL					Assay Description Binding affinity towards alpha-1 adrenergic receptor in rat cortex membrane using [3H]-prazosin radioligand				J Med Chem 44: 2118-32 (2001) Article DOI: 10.1021/jm010821u BindingDB Entry DOI: 10.7270/Q2W3802N
					More data for this Ligand-Target Pair
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM50473252 (CHEMBL302832) Show SMILES COc1ccccc1OCCN1CCN(CC1)c1cnn(CCCCCCCCN2CCN(CC2)c2ccccc2OC)c(=O)c1Cl Show InChI InChI=1S/C36H51ClN6O4/c1-45-32-14-8-7-13-30(32)41-23-19-39(20-24-41)17-11-5-3-4-6-12-18-43-36(44)35(37)31(29-38-43)42-25-21-40(22-26-42)27-28-47-34-16-10-9-15-33(34)46-2/h7-10,13-16,29H,3-6,11-12,17-28H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	3.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Perugia Curated by ChEMBL					Assay Description Binding affinity towards alpha-1 adrenergic receptor in rat cortex membrane using [3H]-prazosin radioligand				J Med Chem 44: 2118-32 (2001) Article DOI: 10.1021/jm010821u BindingDB Entry DOI: 10.7270/Q2W3802N
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor (RAT-NEONATAL RAT-Rattus norvegicus (rat))	BDBM50473295 (CHEMBL66172) Show SMILES COc1ccccc1OCCN1CCN(CC1)c1cnn(CCCCCCN2CCN(CC2)c2ccccc2OC)c(=O)c1Cl Show InChI InChI=1S/C34H47ClN6O4/c1-43-30-12-6-5-11-28(30)39-21-17-37(18-22-39)15-9-3-4-10-16-41-34(42)33(35)29(27-36-41)40-23-19-38(20-24-40)25-26-45-32-14-8-7-13-31(32)44-2/h5-8,11-14,27H,3-4,9-10,15-26H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	3.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Perugia Curated by ChEMBL					Assay Description Binding affinity towards alpha-2 adrenergic receptor in rat cortex membrane using [3H]rauwolscine radioligand				J Med Chem 44: 2118-32 (2001) Article DOI: 10.1021/jm010821u BindingDB Entry DOI: 10.7270/Q2W3802N
					More data for this Ligand-Target Pair
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM50473272 (CHEMBL66272) Show SMILES Clc1ccccc1N1CCN(CCCn2ncc(N3CCN(CC3)C(=O)c3ccco3)c(Cl)c2=O)CC1 Show InChI InChI=1S/C26H30Cl2N6O3/c27-20-5-1-2-6-21(20)31-12-10-30(11-13-31)8-4-9-34-26(36)24(28)22(19-29-34)32-14-16-33(17-15-32)25(35)23-7-3-18-37-23/h1-3,5-7,18-19H,4,8-17H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	3.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Perugia Curated by ChEMBL					Assay Description Binding affinity towards alpha-1 adrenergic receptor in rat cortex membrane using [3H]-prazosin radioligand				J Med Chem 44: 2118-32 (2001) Article DOI: 10.1021/jm010821u BindingDB Entry DOI: 10.7270/Q2W3802N
					More data for this Ligand-Target Pair
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM50473290 (CHEMBL65963) Show SMILES Clc1ccccc1N1CCN(CCCCCn2ncc(N3CCN(CC3)C(=O)c3ccco3)c(Cl)c2=O)CC1 Show InChI InChI=1S/C28H34Cl2N6O3/c29-22-7-2-3-8-23(22)33-14-12-32(13-15-33)10-4-1-5-11-36-28(38)26(30)24(21-31-36)34-16-18-35(19-17-34)27(37)25-9-6-20-39-25/h2-3,6-9,20-21H,1,4-5,10-19H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	3.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Perugia Curated by ChEMBL					Assay Description Binding affinity towards alpha-1 adrenergic receptor in rat cortex membrane using [3H]-prazosin radioligand				J Med Chem 44: 2118-32 (2001) Article DOI: 10.1021/jm010821u BindingDB Entry DOI: 10.7270/Q2W3802N
					More data for this Ligand-Target Pair
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM50473287 (CHEMBL304783) Show SMILES COc1ccccc1OCCN1CCN(CC1)c1cnn(CCCCCN2CCN(CC2)c2ccccc2OC)c(=O)c1Cl Show InChI InChI=1S/C33H45ClN6O4/c1-42-29-11-5-4-10-27(29)38-20-16-36(17-21-38)14-8-3-9-15-40-33(41)32(34)28(26-35-40)39-22-18-37(19-23-39)24-25-44-31-13-7-6-12-30(31)43-2/h4-7,10-13,26H,3,8-9,14-25H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	3.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Perugia Curated by ChEMBL					Assay Description Binding affinity towards alpha-1 adrenergic receptor in rat cortex membrane using [3H]-prazosin radioligand				J Med Chem 44: 2118-32 (2001) Article DOI: 10.1021/jm010821u BindingDB Entry DOI: 10.7270/Q2W3802N
					More data for this Ligand-Target Pair
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM50473267 (CHEMBL67379) Show SMILES Clc1ccccc1N1CCN(CCn2ncc(N3CCN(CC3)C(=O)c3ccco3)c(Cl)c2=O)CC1 Show InChI InChI=1S/C25H28Cl2N6O3/c26-19-4-1-2-5-20(19)30-10-7-29(8-11-30)9-16-33-25(35)23(27)21(18-28-33)31-12-14-32(15-13-31)24(34)22-6-3-17-36-22/h1-6,17-18H,7-16H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	3.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Perugia Curated by ChEMBL					Assay Description Binding affinity towards alpha-1 adrenergic receptor in rat cortex membrane using [3H]-prazosin radioligand				J Med Chem 44: 2118-32 (2001) Article DOI: 10.1021/jm010821u BindingDB Entry DOI: 10.7270/Q2W3802N
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor (RAT-NEONATAL RAT-Rattus norvegicus (rat))	BDBM50026636 (17alpha-hydroxy-20alpha-yohimban-16beta-carboxylic...) Show SMILES COC(=O)[C@@H]1[C@@H](O)CC[C@@H]2CN3CCc4c([nH]c5ccccc45)[C@@H]3C[C@H]12 |r| Show InChI InChI=1S/C21H26N2O3/c1-26-21(25)19-15-10-17-20-14(13-4-2-3-5-16(13)22-20)8-9-23(17)11-12(15)6-7-18(19)24/h2-5,12,15,17-19,22,24H,6-11H2,1H3/t12-,15+,17+,18+,19+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Perugia Curated by ChEMBL					Assay Description Binding affinity towards alpha-2 adrenergic receptor in rat cortex membrane using [3H]rauwolscine radioligand				J Med Chem 44: 2118-32 (2001) Article DOI: 10.1021/jm010821u BindingDB Entry DOI: 10.7270/Q2W3802N
					More data for this Ligand-Target Pair
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM50473271 (CHEMBL302268) Show SMILES COc1ccccc1N1CCN(CCCCCCn2ncc(N3CCN(CC3)C(=O)c3ccco3)c(Cl)c2=O)CC1 Show InChI InChI=1S/C30H39ClN6O4/c1-40-26-10-5-4-9-24(26)34-16-14-33(15-17-34)12-6-2-3-7-13-37-30(39)28(31)25(23-32-37)35-18-20-36(21-19-35)29(38)27-11-8-22-41-27/h4-5,8-11,22-23H,2-3,6-7,12-21H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	4.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Perugia Curated by ChEMBL					Assay Description Binding affinity towards alpha-1 adrenergic receptor in rat cortex membrane using [3H]-prazosin radioligand				J Med Chem 44: 2118-32 (2001) Article DOI: 10.1021/jm010821u BindingDB Entry DOI: 10.7270/Q2W3802N
					More data for this Ligand-Target Pair
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM50473286 (CHEMBL303347) Show SMILES COc1ccccc1OCCN1CCN(CC1)c1cnn(CCCCCCN2CCN(CC2)c2ccccc2Cl)c(=O)c1Cl Show InChI InChI=1S/C33H44Cl2N6O3/c1-43-30-12-6-7-13-31(30)44-25-24-38-18-22-40(23-19-38)29-26-36-41(33(42)32(29)35)15-9-3-2-8-14-37-16-20-39(21-17-37)28-11-5-4-10-27(28)34/h4-7,10-13,26H,2-3,8-9,14-25H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	4.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Perugia Curated by ChEMBL					Assay Description Binding affinity towards alpha-1 adrenergic receptor in rat cortex membrane using [3H]-prazosin radioligand				J Med Chem 44: 2118-32 (2001) Article DOI: 10.1021/jm010821u BindingDB Entry DOI: 10.7270/Q2W3802N
					More data for this Ligand-Target Pair
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM50473244 (CHEMBL66747) Show SMILES COc1ccccc1OCCN1CCN(CC1)c1cnn(CCCCN2CCN(CC2)c2ccccc2OC)c(=O)c1Cl Show InChI InChI=1S/C32H43ClN6O4/c1-41-28-10-4-3-9-26(28)37-19-15-35(16-20-37)13-7-8-14-39-32(40)31(33)27(25-34-39)38-21-17-36(18-22-38)23-24-43-30-12-6-5-11-29(30)42-2/h3-6,9-12,25H,7-8,13-24H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	4.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Perugia Curated by ChEMBL					Assay Description Binding affinity towards alpha-1 adrenergic receptor in rat cortex membrane using [3H]-prazosin radioligand				J Med Chem 44: 2118-32 (2001) Article DOI: 10.1021/jm010821u BindingDB Entry DOI: 10.7270/Q2W3802N
					More data for this Ligand-Target Pair
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM50473255 (CHEMBL303894) Show SMILES COc1ccccc1OCCN1CCN(CC1)c1cnn(CCCCCN2CCN(CC2)c2ccccc2Cl)c(=O)c1Cl Show InChI InChI=1S/C32H42Cl2N6O3/c1-42-29-11-5-6-12-30(29)43-24-23-37-17-21-39(22-18-37)28-25-35-40(32(41)31(28)34)14-8-2-7-13-36-15-19-38(20-16-36)27-10-4-3-9-26(27)33/h3-6,9-12,25H,2,7-8,13-24H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	4.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Perugia Curated by ChEMBL					Assay Description Binding affinity towards alpha-1 adrenergic receptor in rat cortex membrane using [3H]-prazosin radioligand				J Med Chem 44: 2118-32 (2001) Article DOI: 10.1021/jm010821u BindingDB Entry DOI: 10.7270/Q2W3802N
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor (RAT-NEONATAL RAT-Rattus norvegicus (rat))	BDBM50222012 (CHEMBL49152) Show SMILES COc1ccccc1OCCN1CCN(CC1)c1cnn(CCCCCCCN2CCN(CC2)c2ccccc2OC)c(=O)c1Cl Show InChI InChI=1S/C35H49ClN6O4/c1-44-31-13-7-6-12-29(31)40-22-18-38(19-23-40)16-10-4-3-5-11-17-42-35(43)34(36)30(28-37-42)41-24-20-39(21-25-41)26-27-46-33-15-9-8-14-32(33)45-2/h6-9,12-15,28H,3-5,10-11,16-27H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	4.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Perugia Curated by ChEMBL					Assay Description Binding affinity towards alpha-2 adrenergic receptor in rat cortex membrane using [3H]rauwolscine radioligand				J Med Chem 44: 2118-32 (2001) Article DOI: 10.1021/jm010821u BindingDB Entry DOI: 10.7270/Q2W3802N
					More data for this Ligand-Target Pair
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM50473259 (CHEMBL304325) Show SMILES COc1ccccc1OCCN1CCN(CC1)c1cnn(CCCCCCCCN2CCN(CC2)c2ccccc2Cl)c(=O)c1Cl Show InChI InChI=1S/C35H48Cl2N6O3/c1-45-32-14-8-9-15-33(32)46-27-26-40-20-24-42(25-21-40)31-28-38-43(35(44)34(31)37)17-11-5-3-2-4-10-16-39-18-22-41(23-19-39)30-13-7-6-12-29(30)36/h6-9,12-15,28H,2-5,10-11,16-27H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	5.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Perugia Curated by ChEMBL					Assay Description Binding affinity towards alpha-1 adrenergic receptor in rat cortex membrane using [3H]-prazosin radioligand				J Med Chem 44: 2118-32 (2001) Article DOI: 10.1021/jm010821u BindingDB Entry DOI: 10.7270/Q2W3802N
					More data for this Ligand-Target Pair
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM50473276 (CHEMBL302857) Show SMILES Clc1ccccc1N1CCN(CCCCCCCn2nc(ccc2=O)N2CCN(CC2)C(=O)c2ccco2)CC1 Show InChI InChI=1S/C30H39ClN6O3/c31-25-9-4-5-10-26(25)34-18-16-33(17-19-34)14-6-2-1-3-7-15-37-29(38)13-12-28(32-37)35-20-22-36(23-21-35)30(39)27-11-8-24-40-27/h4-5,8-13,24H,1-3,6-7,14-23H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	5.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Perugia Curated by ChEMBL					Assay Description Binding affinity towards alpha-1 adrenergic receptor in rat cortex membrane using [3H]-prazosin radioligand				J Med Chem 44: 2118-32 (2001) Article DOI: 10.1021/jm010821u BindingDB Entry DOI: 10.7270/Q2W3802N
					More data for this Ligand-Target Pair
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM50473269 (CHEMBL68447) Show SMILES Clc1ccccc1N1CCN(CCCCCCn2ncc(N3CCN(CC3)C(=O)c3ccco3)c(Cl)c2=O)CC1 Show InChI InChI=1S/C29H36Cl2N6O3/c30-23-8-3-4-9-24(23)34-15-13-33(14-16-34)11-5-1-2-6-12-37-29(39)27(31)25(22-32-37)35-17-19-36(20-18-35)28(38)26-10-7-21-40-26/h3-4,7-10,21-22H,1-2,5-6,11-20H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	5.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Perugia Curated by ChEMBL					Assay Description Binding affinity towards alpha-1 adrenergic receptor in rat cortex membrane using [3H]-prazosin radioligand				J Med Chem 44: 2118-32 (2001) Article DOI: 10.1021/jm010821u BindingDB Entry DOI: 10.7270/Q2W3802N
					More data for this Ligand-Target Pair
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM50473301 (CHEMBL66965) Show SMILES Clc1ccccc1N1CCN(CCCCCCn2nc(ccc2=O)N2CCN(CC2)C(=O)c2ccco2)CC1 Show InChI InChI=1S/C29H37ClN6O3/c30-24-8-3-4-9-25(24)33-17-15-32(16-18-33)13-5-1-2-6-14-36-28(37)12-11-27(31-36)34-19-21-35(22-20-34)29(38)26-10-7-23-39-26/h3-4,7-12,23H,1-2,5-6,13-22H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	5.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Perugia Curated by ChEMBL					Assay Description Binding affinity towards alpha-1 adrenergic receptor in rat cortex membrane using [3H]-prazosin radioligand				J Med Chem 44: 2118-32 (2001) Article DOI: 10.1021/jm010821u BindingDB Entry DOI: 10.7270/Q2W3802N
					More data for this Ligand-Target Pair
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM50473283 (CHEMBL67681) Show SMILES COc1ccccc1OCCN1CCN(CC1)c1ccc(=O)n(CCCN2CCN(CC2)c2ccccc2Cl)n1 Show InChI InChI=1S/C30H39ClN6O3/c1-39-27-9-4-5-10-28(27)40-24-23-34-17-21-36(22-18-34)29-11-12-30(38)37(32-29)14-6-13-33-15-19-35(20-16-33)26-8-3-2-7-25(26)31/h2-5,7-12H,6,13-24H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	6.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Perugia Curated by ChEMBL					Assay Description Binding affinity towards alpha-1 adrenergic receptor in rat cortex membrane using [3H]-prazosin radioligand				J Med Chem 44: 2118-32 (2001) Article DOI: 10.1021/jm010821u BindingDB Entry DOI: 10.7270/Q2W3802N
					More data for this Ligand-Target Pair
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM50473294 (CHEMBL67773) Show SMILES COc1ccccc1OCCN1CCN(CC1)c1ccc(=O)n(CCCCCCN2CCN(CC2)c2ccccc2OC)n1 Show InChI InChI=1S/C34H48N6O4/c1-42-30-12-6-5-11-29(30)38-23-19-36(20-24-38)17-9-3-4-10-18-40-34(41)16-15-33(35-40)39-25-21-37(22-26-39)27-28-44-32-14-8-7-13-31(32)43-2/h5-8,11-16H,3-4,9-10,17-28H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Perugia Curated by ChEMBL					Assay Description Binding affinity towards alpha-1 adrenergic receptor in rat cortex membrane using [3H]-prazosin radioligand				J Med Chem 44: 2118-32 (2001) Article DOI: 10.1021/jm010821u BindingDB Entry DOI: 10.7270/Q2W3802N
					More data for this Ligand-Target Pair
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM50473299 (CHEMBL67081) Show SMILES COc1ccccc1OCCN1CCN(CC1)c1ccc(=O)n(CCCCCN2CCN(CC2)c2ccccc2Cl)n1 Show InChI InChI=1S/C32H43ClN6O3/c1-41-29-11-5-6-12-30(29)42-26-25-36-19-23-38(24-20-36)31-13-14-32(40)39(34-31)16-8-2-7-15-35-17-21-37(22-18-35)28-10-4-3-9-27(28)33/h3-6,9-14H,2,7-8,15-26H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Perugia Curated by ChEMBL					Assay Description Binding affinity towards alpha-1 adrenergic receptor in rat cortex membrane using [3H]-prazosin radioligand				J Med Chem 44: 2118-32 (2001) Article DOI: 10.1021/jm010821u BindingDB Entry DOI: 10.7270/Q2W3802N
					More data for this Ligand-Target Pair
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM50473257 (CHEMBL67882) Show SMILES COc1ccccc1OCCN1CCN(CC1)c1ccc(=O)n(CCCN2CCN(CC2)c2ccccc2OC)n1 Show InChI InChI=1S/C31H42N6O4/c1-39-27-9-4-3-8-26(27)35-20-16-33(17-21-35)14-7-15-37-31(38)13-12-30(32-37)36-22-18-34(19-23-36)24-25-41-29-11-6-5-10-28(29)40-2/h3-6,8-13H,7,14-25H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	7.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Perugia Curated by ChEMBL					Assay Description Binding affinity towards alpha-1 adrenergic receptor in rat cortex membrane using [3H]-prazosin radioligand				J Med Chem 44: 2118-32 (2001) Article DOI: 10.1021/jm010821u BindingDB Entry DOI: 10.7270/Q2W3802N
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor (RAT-NEONATAL RAT-Rattus norvegicus (rat))	BDBM50473265 (CHEMBL67132) Show SMILES COc1ccccc1OCCN1CCN(CC1)c1cnn(CCCCCCCN2CCN(CC2)c2ccccc2Cl)c(=O)c1Cl Show InChI InChI=1S/C34H46Cl2N6O3/c1-44-31-13-7-8-14-32(31)45-26-25-39-19-23-41(24-20-39)30-27-37-42(34(43)33(30)36)16-10-4-2-3-9-15-38-17-21-40(22-18-38)29-12-6-5-11-28(29)35/h5-8,11-14,27H,2-4,9-10,15-26H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	7.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Perugia Curated by ChEMBL					Assay Description Binding affinity towards alpha-2 adrenergic receptor in rat cortex membrane using [3H]rauwolscine radioligand				J Med Chem 44: 2118-32 (2001) Article DOI: 10.1021/jm010821u BindingDB Entry DOI: 10.7270/Q2W3802N
					More data for this Ligand-Target Pair
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM50473285 (CHEMBL417745) Show SMILES Clc1ccccc1N1CCN(CCCCn2nc(ccc2=O)N2CCN(CC2)C(=O)c2ccco2)CC1 Show InChI InChI=1S/C27H33ClN6O3/c28-22-6-1-2-7-23(22)31-15-13-30(14-16-31)11-3-4-12-34-26(35)10-9-25(29-34)32-17-19-33(20-18-32)27(36)24-8-5-21-37-24/h1-2,5-10,21H,3-4,11-20H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	7.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Perugia Curated by ChEMBL					Assay Description Binding affinity towards alpha-1 adrenergic receptor in rat cortex membrane using [3H]-prazosin radioligand				J Med Chem 44: 2118-32 (2001) Article DOI: 10.1021/jm010821u BindingDB Entry DOI: 10.7270/Q2W3802N
					More data for this Ligand-Target Pair
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM50473281 (CHEMBL441444) Show SMILES COc1ccc(Cl)cc1N1CCN(CCCn2nc(-c3ccccc3)c3c(C)onc3c2=O)CC1 Show InChI InChI=1S/C26H28ClN5O3/c1-18-23-24(19-7-4-3-5-8-19)28-32(26(33)25(23)29-35-18)12-6-11-30-13-15-31(16-14-30)21-17-20(27)9-10-22(21)34-2/h3-5,7-10,17H,6,11-16H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	7.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Perugia Curated by ChEMBL					Assay Description Binding affinity towards alpha-1 adrenergic receptor in rat cortex membrane using [3H]-prazosin radioligand				J Med Chem 44: 2118-32 (2001) Article DOI: 10.1021/jm010821u BindingDB Entry DOI: 10.7270/Q2W3802N
					More data for this Ligand-Target Pair
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM50473297 (CHEMBL306440) Show SMILES COc1ccccc1OCCN1CCN(CC1)c1ccc(=O)n(CCCCCCN2CCN(CC2)c2ccccc2Cl)n1 Show InChI InChI=1S/C33H45ClN6O3/c1-42-30-12-6-7-13-31(30)43-27-26-37-20-24-39(25-21-37)32-14-15-33(41)40(35-32)17-9-3-2-8-16-36-18-22-38(23-19-36)29-11-5-4-10-28(29)34/h4-7,10-15H,2-3,8-9,16-27H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	8.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Perugia Curated by ChEMBL					Assay Description Binding affinity towards alpha-1 adrenergic receptor in rat cortex membrane using [3H]-prazosin radioligand				J Med Chem 44: 2118-32 (2001) Article DOI: 10.1021/jm010821u BindingDB Entry DOI: 10.7270/Q2W3802N
					More data for this Ligand-Target Pair
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM50473264 (CHEMBL303895) Show SMILES COc1ccccc1OCCN1CCN(CC1)c1cnn(CCCCN2CCN(CC2)c2ccccc2Cl)c(=O)c1Cl Show InChI InChI=1S/C31H40Cl2N6O3/c1-41-28-10-4-5-11-29(28)42-23-22-36-16-20-38(21-17-36)27-24-34-39(31(40)30(27)33)13-7-6-12-35-14-18-37(19-15-35)26-9-3-2-8-25(26)32/h2-5,8-11,24H,6-7,12-23H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Perugia Curated by ChEMBL					Assay Description Binding affinity towards alpha-1 adrenergic receptor in rat cortex membrane using [3H]-prazosin radioligand				J Med Chem 44: 2118-32 (2001) Article DOI: 10.1021/jm010821u BindingDB Entry DOI: 10.7270/Q2W3802N
					More data for this Ligand-Target Pair
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM50473288 (CHEMBL67114) Show SMILES Clc1ccccc1N1CCN(CCCCCCCn2ncc(N3CCN(CC3)C(=O)c3ccco3)c(Cl)c2=O)CC1 Show InChI InChI=1S/C30H38Cl2N6O3/c31-24-9-4-5-10-25(24)35-16-14-34(15-17-35)12-6-2-1-3-7-13-38-30(40)28(32)26(23-33-38)36-18-20-37(21-19-36)29(39)27-11-8-22-41-27/h4-5,8-11,22-23H,1-3,6-7,12-21H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Perugia Curated by ChEMBL					Assay Description Binding affinity towards alpha-1 adrenergic receptor in rat cortex membrane using [3H]-prazosin radioligand				J Med Chem 44: 2118-32 (2001) Article DOI: 10.1021/jm010821u BindingDB Entry DOI: 10.7270/Q2W3802N
					More data for this Ligand-Target Pair
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM50051166 (1-(4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl)pyrr...) Show SMILES COc1ccccc1N1CCN(CCCCN2C(=O)CCC2=O)CC1 Show InChI InChI=1S/C19H27N3O3/c1-25-17-7-3-2-6-16(17)21-14-12-20(13-15-21)10-4-5-11-22-18(23)8-9-19(22)24/h2-3,6-7H,4-5,8-15H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Perugia Curated by ChEMBL					Assay Description Alpha-1 adrenergic receptor binding affinity of the compound, value taken from literature				J Med Chem 44: 2118-32 (2001) Article DOI: 10.1021/jm010821u BindingDB Entry DOI: 10.7270/Q2W3802N
					More data for this Ligand-Target Pair
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM50473258 (CHEMBL417565) Show SMILES Clc1ccccc1N1CCN(CCCCCn2nc(ccc2=O)N2CCN(CC2)C(=O)c2ccco2)CC1 Show InChI InChI=1S/C28H35ClN6O3/c29-23-7-2-3-8-24(23)32-16-14-31(15-17-32)12-4-1-5-13-35-27(36)11-10-26(30-35)33-18-20-34(21-19-33)28(37)25-9-6-22-38-25/h2-3,6-11,22H,1,4-5,12-21H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Perugia Curated by ChEMBL					Assay Description Binding affinity towards alpha-1 adrenergic receptor in rat cortex membrane using [3H]-prazosin radioligand				J Med Chem 44: 2118-32 (2001) Article DOI: 10.1021/jm010821u BindingDB Entry DOI: 10.7270/Q2W3802N
					More data for this Ligand-Target Pair
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM50473250 (CHEMBL66748) Show SMILES COc1ccccc1OCCN1CCN(CC1)c1ccc(=O)n(CCCCCN2CCN(CC2)c2ccccc2OC)n1 Show InChI InChI=1S/C33H46N6O4/c1-41-29-11-5-4-10-28(29)37-22-18-35(19-23-37)16-8-3-9-17-39-33(40)15-14-32(34-39)38-24-20-36(21-25-38)26-27-43-31-13-7-6-12-30(31)42-2/h4-7,10-15H,3,8-9,16-27H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Perugia Curated by ChEMBL					Assay Description Binding affinity towards alpha-1 adrenergic receptor in rat cortex membrane using [3H]-prazosin radioligand				J Med Chem 44: 2118-32 (2001) Article DOI: 10.1021/jm010821u BindingDB Entry DOI: 10.7270/Q2W3802N
					More data for this Ligand-Target Pair
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM50473291 (CHEMBL63876) Show SMILES Clc1ccccc1N1CCN(CCCn2nc(ccc2=O)N2CCN(CC2)C(=O)c2ccco2)CC1 Show InChI InChI=1S/C26H31ClN6O3/c27-21-5-1-2-6-22(21)30-14-12-29(13-15-30)10-4-11-33-25(34)9-8-24(28-33)31-16-18-32(19-17-31)26(35)23-7-3-20-36-23/h1-3,5-9,20H,4,10-19H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Perugia Curated by ChEMBL					Assay Description Binding affinity towards alpha-1 adrenergic receptor in rat cortex membrane using [3H]-prazosin radioligand				J Med Chem 44: 2118-32 (2001) Article DOI: 10.1021/jm010821u BindingDB Entry DOI: 10.7270/Q2W3802N
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor (RAT-NEONATAL RAT-Rattus norvegicus (rat))	BDBM50473287 (CHEMBL304783) Show SMILES COc1ccccc1OCCN1CCN(CC1)c1cnn(CCCCCN2CCN(CC2)c2ccccc2OC)c(=O)c1Cl Show InChI InChI=1S/C33H45ClN6O4/c1-42-29-11-5-4-10-27(29)38-20-16-36(17-21-38)14-8-3-9-15-40-33(41)32(34)28(26-35-40)39-22-18-37(19-23-39)24-25-44-31-13-7-6-12-30(31)43-2/h4-7,10-13,26H,3,8-9,14-25H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Perugia Curated by ChEMBL					Assay Description Binding affinity towards alpha-2 adrenergic receptor in rat cortex membrane using [3H]rauwolscine radioligand				J Med Chem 44: 2118-32 (2001) Article DOI: 10.1021/jm010821u BindingDB Entry DOI: 10.7270/Q2W3802N
					More data for this Ligand-Target Pair
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM50473270 (CHEMBL302051) Show SMILES COc1ccccc1OCCN1CCN(CC1)c1ccc(=O)n(CCCCCCCN2CCN(CC2)c2ccccc2Cl)n1 Show InChI InChI=1S/C34H47ClN6O3/c1-43-31-13-7-8-14-32(31)44-28-27-38-21-25-40(26-22-38)33-15-16-34(42)41(36-33)18-10-4-2-3-9-17-37-19-23-39(24-20-37)30-12-6-5-11-29(30)35/h5-8,11-16H,2-4,9-10,17-28H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Perugia Curated by ChEMBL					Assay Description Binding affinity towards alpha-1 adrenergic receptor in rat cortex membrane using [3H]-prazosin radioligand				J Med Chem 44: 2118-32 (2001) Article DOI: 10.1021/jm010821u BindingDB Entry DOI: 10.7270/Q2W3802N
					More data for this Ligand-Target Pair
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM50473248 (CHEMBL67639) Show SMILES COc1ccccc1OCCN1CCN(CC1)c1cnn(CCCN2CCN(CC2)c2ccccc2OC)c(=O)c1Cl Show InChI InChI=1S/C31H41ClN6O4/c1-40-27-9-4-3-8-25(27)36-18-14-34(15-19-36)12-7-13-38-31(39)30(32)26(24-33-38)37-20-16-35(17-21-37)22-23-42-29-11-6-5-10-28(29)41-2/h3-6,8-11,24H,7,12-23H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Perugia Curated by ChEMBL					Assay Description Binding affinity towards alpha-1 adrenergic receptor in rat cortex membrane using [3H]-prazosin radioligand				J Med Chem 44: 2118-32 (2001) Article DOI: 10.1021/jm010821u BindingDB Entry DOI: 10.7270/Q2W3802N
					More data for this Ligand-Target Pair
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM50473280 (CHEMBL303130) Show SMILES COc1ccccc1OCCN1CCN(CC1)c1cnn(CCN2CCN(CC2)c2ccccc2OC)c(=O)c1Cl Show InChI InChI=1S/C30H39ClN6O4/c1-39-26-8-4-3-7-24(26)35-16-11-33(12-17-35)15-20-37-30(38)29(31)25(23-32-37)36-18-13-34(14-19-36)21-22-41-28-10-6-5-9-27(28)40-2/h3-10,23H,11-22H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Perugia Curated by ChEMBL					Assay Description Binding affinity towards alpha-1 adrenergic receptor in rat cortex membrane using [3H]-prazosin radioligand				J Med Chem 44: 2118-32 (2001) Article DOI: 10.1021/jm010821u BindingDB Entry DOI: 10.7270/Q2W3802N
					More data for this Ligand-Target Pair
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM50473289 (CHEMBL444582) Show SMILES COc1ccc(Cl)cc1N1CCN(CCn2nc(-c3ccccc3)c3c(C)onc3c2=O)CC1 Show InChI InChI=1S/C25H26ClN5O3/c1-17-22-23(18-6-4-3-5-7-18)27-31(25(32)24(22)28-34-17)15-12-29-10-13-30(14-11-29)20-16-19(26)8-9-21(20)33-2/h3-9,16H,10-15H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Perugia Curated by ChEMBL					Assay Description Binding affinity towards alpha-1 adrenergic receptor in rat cortex membrane using [3H]-prazosin radioligand				J Med Chem 44: 2118-32 (2001) Article DOI: 10.1021/jm010821u BindingDB Entry DOI: 10.7270/Q2W3802N
					More data for this Ligand-Target Pair
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM50473246 (CHEMBL70173) Show SMILES COc1ccccc1N1CCN(CCCCCCn2nc(ccc2=O)N2CCN(CC2)C(=O)c2ccco2)CC1 Show InChI InChI=1S/C30H40N6O4/c1-39-26-10-5-4-9-25(26)33-18-16-32(17-19-33)14-6-2-3-7-15-36-29(37)13-12-28(31-36)34-20-22-35(23-21-34)30(38)27-11-8-24-40-27/h4-5,8-13,24H,2-3,6-7,14-23H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Perugia Curated by ChEMBL					Assay Description Binding affinity towards alpha-1 adrenergic receptor in rat cortex membrane using [3H]-prazosin radioligand				J Med Chem 44: 2118-32 (2001) Article DOI: 10.1021/jm010821u BindingDB Entry DOI: 10.7270/Q2W3802N
					More data for this Ligand-Target Pair
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor (RAT-NEONATAL RAT-Rattus norvegicus (rat))	BDBM50473290 (CHEMBL65963) Show SMILES Clc1ccccc1N1CCN(CCCCCn2ncc(N3CCN(CC3)C(=O)c3ccco3)c(Cl)c2=O)CC1 Show InChI InChI=1S/C28H34Cl2N6O3/c29-22-7-2-3-8-23(22)33-14-12-32(13-15-33)10-4-1-5-11-36-28(38)26(30)24(21-31-36)34-16-18-35(19-17-34)27(37)25-9-6-20-39-25/h2-3,6-9,20-21H,1,4-5,10-19H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Perugia Curated by ChEMBL					Assay Description Binding affinity towards alpha-2 adrenergic receptor in rat cortex membrane using [3H]rauwolscine radioligand				J Med Chem 44: 2118-32 (2001) Article DOI: 10.1021/jm010821u BindingDB Entry DOI: 10.7270/Q2W3802N
					More data for this Ligand-Target Pair

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