Compile Data Set for Download or QSAR

Found 26 hits Enz. Inhib. hit(s) with all data for entry = 50014546   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Adenylate cyclase type 10 (Homo sapiens (Human))	BDBM50577248 (CHEMBL4878379) Show SMILES COC(=O)c1c(Cc2ccccc2)c(nn1C)-c1cc(Cl)nc(N)n1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human soluble adenylyl cyclase assessed as reduction in cAMP levels in the presence of alpha-32p labeled ATP by biochemical assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00273 BindingDB Entry DOI: 10.7270/Q29S1VWQ
					More data for this Ligand-Target Pair
Adenylate cyclase type 10 (Homo sapiens (Human))	BDBM50577241 (CHEMBL4848035) Show SMILES Cc1c(Cc2cccs2)c(nn1C)-c1cc(Cl)nc(N)n1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	74	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human soluble adenylyl cyclase assessed as reduction in cAMP levels in the presence of alpha-32p labeled ATP by biochemical assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00273 BindingDB Entry DOI: 10.7270/Q29S1VWQ
					More data for this Ligand-Target Pair
Adenylate cyclase type 10 (Homo sapiens (Human))	BDBM50577242 (CHEMBL4854762) Show SMILES Cc1c(Cc2ccccc2)c(nn1C)-c1cc(Cl)nc(N)n1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	92	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human soluble adenylyl cyclase transfected (4-4 clones)in human HEK293 cells assessed as reduction in cAMP levels preincubated for 5 mi...				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00273 BindingDB Entry DOI: 10.7270/Q29S1VWQ
					More data for this Ligand-Target Pair				3D Structure (crystal)
Adenylate cyclase type 10 (Homo sapiens (Human))	BDBM50577241 (CHEMBL4848035) Show SMILES Cc1c(Cc2cccs2)c(nn1C)-c1cc(Cl)nc(N)n1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	102	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human soluble adenylyl cyclase transfected (4-4 clones)in human HEK293 cells assessed as reduction in cAMP levels preincubated for 5 mi...				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00273 BindingDB Entry DOI: 10.7270/Q29S1VWQ
					More data for this Ligand-Target Pair
Adenylate cyclase type 10 (Homo sapiens (Human))	BDBM50577243 (CHEMBL4868801) Show SMILES Cc1c(Cc2cccc(Cl)c2)c(nn1C)-c1cc(Cl)nc(N)n1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	107	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human soluble adenylyl cyclase assessed as reduction in cAMP levels in the presence of alpha-32p labeled ATP by biochemical assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00273 BindingDB Entry DOI: 10.7270/Q29S1VWQ
					More data for this Ligand-Target Pair
Adenylate cyclase type 10 (Homo sapiens (Human))	BDBM50577244 (CHEMBL4864668) Show SMILES Cc1c(Cc2cccc(F)c2)c(nn1C)-c1cc(Cl)nc(N)n1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	126	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human soluble adenylyl cyclase assessed as reduction in cAMP levels in the presence of alpha-32p labeled ATP by biochemical assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00273 BindingDB Entry DOI: 10.7270/Q29S1VWQ
					More data for this Ligand-Target Pair
Adenylate cyclase type 10 (Homo sapiens (Human))	BDBM50577236 (CHEMBL4857305) Show SMILES Cn1cc(Cc2ccccc2F)c(n1)-c1cc(Cl)nc(N)n1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	132	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human soluble adenylyl cyclase assessed as reduction in cAMP levels in the presence of alpha-32p labeled ATP by biochemical assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00273 BindingDB Entry DOI: 10.7270/Q29S1VWQ
					More data for this Ligand-Target Pair
Adenylate cyclase type 10 (Homo sapiens (Human))	BDBM50577232 (CHEMBL4849033) Show SMILES Cn1cc(Cc2cccs2)c(n1)-c1cc(Cl)nc(N)n1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	141	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human soluble adenylyl cyclase assessed as reduction in cAMP levels in the presence of alpha-32p labeled ATP by biochemical assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00273 BindingDB Entry DOI: 10.7270/Q29S1VWQ
					More data for this Ligand-Target Pair				3D Structure (crystal)
Adenylate cyclase type 10 (Homo sapiens (Human))	BDBM50577242 (CHEMBL4854762) Show SMILES Cc1c(Cc2ccccc2)c(nn1C)-c1cc(Cl)nc(N)n1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	195	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human soluble adenylyl cyclase assessed as reduction in cAMP levels in the presence of alpha-32p labeled ATP by biochemical assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00273 BindingDB Entry DOI: 10.7270/Q29S1VWQ
					More data for this Ligand-Target Pair				3D Structure (crystal)
Adenylate cyclase type 10 (Homo sapiens (Human))	BDBM50577232 (CHEMBL4849033) Show SMILES Cn1cc(Cc2cccs2)c(n1)-c1cc(Cl)nc(N)n1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	196	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human soluble adenylyl cyclase transfected (4-4 clones)in human HEK293 cells assessed as reduction in cAMP levels preincubated for 5 mi...				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00273 BindingDB Entry DOI: 10.7270/Q29S1VWQ
					More data for this Ligand-Target Pair				3D Structure (crystal)
Adenylate cyclase type 10 (Homo sapiens (Human))	BDBM50577233 (CHEMBL4874288) Show SMILES Cn1cc(Cc2cccc(F)c2)c(n1)-c1cc(Cl)nc(N)n1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	225	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human soluble adenylyl cyclase transfected (4-4 clones)in human HEK293 cells assessed as reduction in cAMP levels preincubated for 5 mi...				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00273 BindingDB Entry DOI: 10.7270/Q29S1VWQ
					More data for this Ligand-Target Pair				3D Structure (crystal)
Adenylate cyclase type 10 (Homo sapiens (Human))	BDBM50577245 (CHEMBL4866319) Show SMILES Cc1c(Cn2cccn2)c(nn1C)-c1cc(Cl)nc(N)n1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	325	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human soluble adenylyl cyclase assessed as reduction in cAMP levels in the presence of alpha-32p labeled ATP by biochemical assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00273 BindingDB Entry DOI: 10.7270/Q29S1VWQ
					More data for this Ligand-Target Pair
Adenylate cyclase type 10 (Homo sapiens (Human))	BDBM50577234 (CHEMBL4864843) Show SMILES Cn1cc(Cc2ccc(F)cc2)c(n1)-c1cc(Cl)nc(N)n1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	342	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human soluble adenylyl cyclase assessed as reduction in cAMP levels in the presence of alpha-32p labeled ATP by biochemical assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00273 BindingDB Entry DOI: 10.7270/Q29S1VWQ
					More data for this Ligand-Target Pair
Adenylate cyclase type 10 (Homo sapiens (Human))	BDBM50577235 (CHEMBL4867202) Show SMILES COc1cccc(Cc2cn(C)nc2-c2cc(Cl)nc(N)n2)c1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	351	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human soluble adenylyl cyclase assessed as reduction in cAMP levels in the presence of alpha-32p labeled ATP by biochemical assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00273 BindingDB Entry DOI: 10.7270/Q29S1VWQ
					More data for this Ligand-Target Pair
Adenylate cyclase type 10 (Homo sapiens (Human))	BDBM50577233 (CHEMBL4874288) Show SMILES Cn1cc(Cc2cccc(F)c2)c(n1)-c1cc(Cl)nc(N)n1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	392	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human soluble adenylyl cyclase assessed as reduction in cAMP levels in the presence of alpha-32p labeled ATP by biochemical assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00273 BindingDB Entry DOI: 10.7270/Q29S1VWQ
					More data for this Ligand-Target Pair				3D Structure (crystal)
Adenylate cyclase type 10 (Homo sapiens (Human))	BDBM50577238 (CHEMBL4866035) Show SMILES Cn1cc(Cc2cncs2)c(n1)-c1cc(Cl)nc(N)n1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	576	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human soluble adenylyl cyclase assessed as reduction in cAMP levels in the presence of alpha-32p labeled ATP by biochemical assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00273 BindingDB Entry DOI: 10.7270/Q29S1VWQ
					More data for this Ligand-Target Pair
Adenylate cyclase type 10 (Homo sapiens (Human))	BDBM50577249 (CHEMBL4878049) Show SMILES Cn1nc(c(Cc2ccccc2)c1C(O)=O)-c1cc(Cl)nc(N)n1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human soluble adenylyl cyclase assessed as reduction in cAMP levels in the presence of alpha-32p labeled ATP by biochemical assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00273 BindingDB Entry DOI: 10.7270/Q29S1VWQ
					More data for this Ligand-Target Pair
Adenylate cyclase type 10 (Homo sapiens (Human))	BDBM50577237 (CHEMBL4874934) Show SMILES Cn1cc(Cc2ccccc2)c(n1)-c1cc(Cl)nc(N)n1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	989	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human soluble adenylyl cyclase assessed as reduction in cAMP levels in the presence of alpha-32p labeled ATP by biochemical assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00273 BindingDB Entry DOI: 10.7270/Q29S1VWQ
					More data for this Ligand-Target Pair
Adenylate cyclase type 10 (Homo sapiens (Human))	BDBM50577239 (CHEMBL4862670) Show SMILES Cc1ccc(Cc2cn(C)nc2-c2cc(Cl)nc(N)n2)s1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human soluble adenylyl cyclase assessed as reduction in cAMP levels in the presence of alpha-32p labeled ATP by biochemical assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00273 BindingDB Entry DOI: 10.7270/Q29S1VWQ
					More data for this Ligand-Target Pair
Adenylate cyclase type 10 (Homo sapiens (Human))	BDBM50577240 (CHEMBL4847756) Show SMILES Cc1cc(nc(N)n1)-c1nn(C)cc1Cc1cccs1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human soluble adenylyl cyclase assessed as reduction in cAMP levels in the presence of alpha-32p labeled ATP by biochemical assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00273 BindingDB Entry DOI: 10.7270/Q29S1VWQ
					More data for this Ligand-Target Pair
Adenylate cyclase type 10 (Homo sapiens (Human))	BDBM492902 (US10981899, Example RU-0204277-LRE1) Show SMILES Nc1nc(Cl)cc(n1)N(Cc1cccs1)C1CC1 Show InChI InChI=1S/C12H13ClN4S/c13-10-6-11(16-12(14)15-10)17(8-3-4-8)7-9-2-1-5-18-9/h1-2,5-6,8H,3-4,7H2,(H2,14,15,16)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human soluble adenylyl cyclase assessed as reduction in cAMP levels in the presence of alpha-32p labeled ATP by biochemical assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00273 BindingDB Entry DOI: 10.7270/Q29S1VWQ
					More data for this Ligand-Target Pair				3D Structure (crystal)
Adenylate cyclase type 10 (Homo sapiens (Human))	BDBM50577251 (CHEMBL4870637) Show SMILES Cn1nc(c(Cc2ccccc2)c1CO)-c1cc(Cl)nc(N)n1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.64E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human soluble adenylyl cyclase assessed as reduction in cAMP levels in the presence of alpha-32p labeled ATP by biochemical assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00273 BindingDB Entry DOI: 10.7270/Q29S1VWQ
					More data for this Ligand-Target Pair
Adenylate cyclase type 10 (Homo sapiens (Human))	BDBM50577252 (CHEMBL4854260) Show SMILES CN(C)Cc1c(Cc2ccccc2)c(nn1C)-c1cc(Cl)nc(N)n1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human soluble adenylyl cyclase assessed as reduction in cAMP levels in the presence of alpha-32p labeled ATP by biochemical assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00273 BindingDB Entry DOI: 10.7270/Q29S1VWQ
					More data for this Ligand-Target Pair
Adenylate cyclase type 10 (Homo sapiens (Human))	BDBM50577250 (CHEMBL4868259) Show SMILES CNC(=O)c1c(Cc2ccccc2)c(nn1C)-c1cc(Cl)nc(N)n1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human soluble adenylyl cyclase assessed as reduction in cAMP levels in the presence of alpha-32p labeled ATP by biochemical assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00273 BindingDB Entry DOI: 10.7270/Q29S1VWQ
					More data for this Ligand-Target Pair
Adenylate cyclase type 10 (Homo sapiens (Human))	BDBM50577247 (CHEMBL4874074) Show SMILES Cc1c(Cc2ncccn2)c(nn1C)-c1cc(Cl)nc(N)n1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human soluble adenylyl cyclase assessed as reduction in cAMP levels in the presence of alpha-32p labeled ATP by biochemical assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00273 BindingDB Entry DOI: 10.7270/Q29S1VWQ
					More data for this Ligand-Target Pair
Adenylate cyclase type 10 (Homo sapiens (Human))	BDBM50577246 (CHEMBL4851867) Show SMILES Cc1c(Cc2ccnn2C)c(nn1C)-c1cc(Cl)nc(N)n1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human soluble adenylyl cyclase assessed as reduction in cAMP levels in the presence of alpha-32p labeled ATP by biochemical assay				Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00273 BindingDB Entry DOI: 10.7270/Q29S1VWQ
					More data for this Ligand-Target Pair