Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Neutrophil elastase (Homo sapiens (Human)) | BDBM50285289 (2,6-Dichloro-3-(2-morpholin-4-yl-ethoxy)-benzoic a...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | 0.0220 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of Human Leukocyte Elastase (HLE) as apparent binding constant (kreact/kinact) | Bioorg Med Chem Lett 5: 105-109 (1995) Article DOI: 10.1016/0960-894X(94)00466-S BindingDB Entry DOI: 10.7270/Q2V69JJN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neutrophil elastase (Homo sapiens (Human)) | BDBM50285280 (2,6-Dichloro-benzoic acid 4-ethoxy-6-methoxy-1,1,3...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | 0.0490 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of Human Leukocyte Elastase (HLE) as apparent binding constant (kreact/kinact) | Bioorg Med Chem Lett 5: 105-109 (1995) Article DOI: 10.1016/0960-894X(94)00466-S BindingDB Entry DOI: 10.7270/Q2V69JJN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neutrophil elastase (Homo sapiens (Human)) | BDBM50285286 (2,6-Dichloro-3-(2-morpholin-4-yl-ethoxy)-benzoic a...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | 0.0700 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of Human Leukocyte Elastase (HLE) as apparent binding constant (kreact/kinact) | Bioorg Med Chem Lett 5: 105-109 (1995) Article DOI: 10.1016/0960-894X(94)00466-S BindingDB Entry DOI: 10.7270/Q2V69JJN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neutrophil elastase (Homo sapiens (Human)) | BDBM50285284 (2,6-Dichloro-benzoic acid 4,6-diethoxy-1,1,3-triox...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | 0.0800 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of Human Leukocyte Elastase (HLE) as apparent binding constant (kreact/kinact) | Bioorg Med Chem Lett 5: 105-109 (1995) Article DOI: 10.1016/0960-894X(94)00466-S BindingDB Entry DOI: 10.7270/Q2V69JJN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neutrophil elastase (Homo sapiens (Human)) | BDBM50285283 (2,6-Dichloro-benzoic acid 4,6-dimethoxy-1,1,3-trio...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | 0.0800 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of Human Leukocyte Elastase (HLE) as apparent binding constant (kreact/kinact) | Bioorg Med Chem Lett 5: 105-109 (1995) Article DOI: 10.1016/0960-894X(94)00466-S BindingDB Entry DOI: 10.7270/Q2V69JJN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neutrophil elastase (Homo sapiens (Human)) | BDBM50285287 (2,6-Dichloro-3-(2-pyrrolidin-1-yl-ethoxy)-benzoic ...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | 0.110 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of Human Leukocyte Elastase (HLE) as apparent binding constant (kreact/kinact) | Bioorg Med Chem Lett 5: 105-109 (1995) Article DOI: 10.1016/0960-894X(94)00466-S BindingDB Entry DOI: 10.7270/Q2V69JJN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neutrophil elastase (Homo sapiens (Human)) | BDBM50285290 (2,6-Dichloro-benzoic acid 4-ethoxy-1,1,3-trioxo-1,...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | 0.170 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of Human Leukocyte Elastase (HLE) as apparent binding constant (kreact/kinact) | Bioorg Med Chem Lett 5: 105-109 (1995) Article DOI: 10.1016/0960-894X(94)00466-S BindingDB Entry DOI: 10.7270/Q2V69JJN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neutrophil elastase (Homo sapiens (Human)) | BDBM50285282 (2,6-Dichloro-benzoic acid 4-isopropoxy-1,1,3-triox...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | 0.240 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of Human Leukocyte Elastase (HLE) as apparent binding constant (kreact/kinact) | Bioorg Med Chem Lett 5: 105-109 (1995) Article DOI: 10.1016/0960-894X(94)00466-S BindingDB Entry DOI: 10.7270/Q2V69JJN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neutrophil elastase (Homo sapiens (Human)) | BDBM50285285 (2,6-Dichloro-benzoic acid 6-methoxy-1,1,3-trioxo-4...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | 0.340 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of Human Leukocyte Elastase (HLE) as apparent binding constant (kreact/kinact) | Bioorg Med Chem Lett 5: 105-109 (1995) Article DOI: 10.1016/0960-894X(94)00466-S BindingDB Entry DOI: 10.7270/Q2V69JJN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neutrophil elastase (Homo sapiens (Human)) | BDBM50285288 (2,6-Dichloro-benzoic acid 6-methoxy-1,1,3-trioxo-1...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | 0.470 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of Human Leukocyte Elastase (HLE) as apparent binding constant (kreact/kinact) | Bioorg Med Chem Lett 5: 105-109 (1995) Article DOI: 10.1016/0960-894X(94)00466-S BindingDB Entry DOI: 10.7270/Q2V69JJN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neutrophil elastase (Homo sapiens (Human)) | BDBM50285281 (2,6-Dichloro-benzoic acid 4,5-dimethoxy-1,1,3-trio...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | 1.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of Human Leukocyte Elastase (HLE) as apparent binding constant (kreact/kinact) | Bioorg Med Chem Lett 5: 105-109 (1995) Article DOI: 10.1016/0960-894X(94)00466-S BindingDB Entry DOI: 10.7270/Q2V69JJN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Neutrophil elastase (Homo sapiens (Human)) | BDBM50039636 (2,6-Dichloro-benzoic acid 1,1,3-trioxo-1,3-dihydro...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article | 2.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibition of Human Leukocyte Elastase (HLE) as apparent binding constant (kreact/kinact) | Bioorg Med Chem Lett 5: 105-109 (1995) Article DOI: 10.1016/0960-894X(94)00466-S BindingDB Entry DOI: 10.7270/Q2V69JJN | |||||||||||
More data for this Ligand-Target Pair |