Compile Data Set for Download or QSAR

Found 197 hits Enz. Inhib. hit(s) with all data for assayid = 1 entry = 6511   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
UDP-3-O-acyl-N-acetylglucosamine deacetylase (Pseudomonas aeruginosa)	BDBM135525 (US8853258, 176) Show SMILES CC(CCc1ccc(cc1)-c1ccc2OCOc2c1)(C(=O)NO)S(C)(=O)=O Show InChI InChI=1S/C19H21NO6S/c1-19(18(21)20-22,27(2,23)24)10-9-13-3-5-14(6-4-13)15-7-8-16-17(11-15)26-12-25-16/h3-8,11,22H,9-10,12H2,1-2H3,(H,20,21)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.0303	n/a	n/a	n/a	n/a	8.0	n/a
Pfizer Inc. US Patent					Assay Description IC50 determination in the LpxC enzyme assay was carried out in a similar manner to that described by Malikzay et al in the 2006 Poster, Screening Lpx...				US Patent US8853258 (2014) BindingDB Entry DOI: 10.7270/Q25M64DP
					More data for this Ligand-Target Pair
UDP-3-O-acyl-N-acetylglucosamine deacetylase (Pseudomonas aeruginosa)	BDBM135565 (US8853258, 218) Show SMILES C[C@@](CCc1ccc(cc1)-c1cc2ccccc2[nH]1)(C(=O)NO)S(C)(=O)=O Show InChI InChI=1S/C20H22N2O4S/c1-20(19(23)22-24,27(2,25)26)12-11-14-7-9-15(10-8-14)18-13-16-5-3-4-6-17(16)21-18/h3-10,13,21,24H,11-12H2,1-2H3,(H,22,23)/t20-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.0340	n/a	n/a	n/a	n/a	8.0	n/a
Pfizer Inc. US Patent					Assay Description IC50 determination in the LpxC enzyme assay was carried out in a similar manner to that described by Malikzay et al in the 2006 Poster, Screening Lpx...				US Patent US8853258 (2014) BindingDB Entry DOI: 10.7270/Q25M64DP
					More data for this Ligand-Target Pair
UDP-3-O-acyl-N-acetylglucosamine deacetylase (Pseudomonas aeruginosa)	BDBM135527 (US8853258, 178) Show SMILES CC(CCc1ccc(cc1F)-c1ccc(O)cc1)(C(=O)NO)S(C)(=O)=O Show InChI InChI=1S/C18H20FNO5S/c1-18(17(22)20-23,26(2,24)25)10-9-13-3-4-14(11-16(13)19)12-5-7-15(21)8-6-12/h3-8,11,21,23H,9-10H2,1-2H3,(H,20,22)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.0592	n/a	n/a	n/a	n/a	8.0	n/a
Pfizer Inc. US Patent					Assay Description IC50 determination in the LpxC enzyme assay was carried out in a similar manner to that described by Malikzay et al in the 2006 Poster, Screening Lpx...				US Patent US8853258 (2014) BindingDB Entry DOI: 10.7270/Q25M64DP
					More data for this Ligand-Target Pair
UDP-3-O-acyl-N-acetylglucosamine deacetylase (Pseudomonas aeruginosa)	BDBM135477 (US8853258, 44) Show SMILES CC(CCc1ccc(cc1)-c1ccc(Cl)cc1)(C(=O)NO)S(C)(=O)=O Show InChI InChI=1S/C18H20ClNO4S/c1-18(17(21)20-22,25(2,23)24)12-11-13-3-5-14(6-4-13)15-7-9-16(19)10-8-15/h3-10,22H,11-12H2,1-2H3,(H,20,21)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.0669	n/a	n/a	n/a	n/a	8.0	n/a
Pfizer Inc. US Patent					Assay Description IC50 determination in the LpxC enzyme assay was carried out in a similar manner to that described by Malikzay et al in the 2006 Poster, Screening Lpx...				US Patent US8853258 (2014) BindingDB Entry DOI: 10.7270/Q25M64DP
					More data for this Ligand-Target Pair
UDP-3-O-acyl-N-acetylglucosamine deacetylase (Pseudomonas aeruginosa)	BDBM135531 (US8853258, 182) Show SMILES CC(=O)c1ccc(cc1)-c1ccc(CC[C@](C)(C(=O)NO)S(C)(=O)=O)cc1 Show InChI InChI=1S/C20H23NO5S/c1-14(22)16-8-10-18(11-9-16)17-6-4-15(5-7-17)12-13-20(2,19(23)21-24)27(3,25)26/h4-11,24H,12-13H2,1-3H3,(H,21,23)/t20-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.0674	n/a	n/a	n/a	n/a	8.0	n/a
Pfizer Inc. US Patent					Assay Description IC50 determination in the LpxC enzyme assay was carried out in a similar manner to that described by Malikzay et al in the 2006 Poster, Screening Lpx...				US Patent US8853258 (2014) BindingDB Entry DOI: 10.7270/Q25M64DP
					More data for this Ligand-Target Pair
UDP-3-O-acyl-N-acetylglucosamine deacetylase (Pseudomonas aeruginosa)	BDBM135562 (US8853258, 215) Show SMILES C[C@@](CCc1ccc(cc1)-c1ccc2OCOc2c1)(C(=O)NO)S(C)(=O)=O Show InChI InChI=1S/C19H21NO6S/c1-19(18(21)20-22,27(2,23)24)10-9-13-3-5-14(6-4-13)15-7-8-16-17(11-15)26-12-25-16/h3-8,11,22H,9-10,12H2,1-2H3,(H,20,21)/t19-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.0842	n/a	n/a	n/a	n/a	8.0	n/a
Pfizer Inc. US Patent					Assay Description IC50 determination in the LpxC enzyme assay was carried out in a similar manner to that described by Malikzay et al in the 2006 Poster, Screening Lpx...				US Patent US8853258 (2014) BindingDB Entry DOI: 10.7270/Q25M64DP
					More data for this Ligand-Target Pair
UDP-3-O-acyl-N-acetylglucosamine deacetylase (Pseudomonas aeruginosa)	BDBM135460 (US8853258, 5) Show SMILES CC(CCc1ccc(cc1)-c1ccc(cc1)[N+]([O-])=O)(C(=O)NO)S(C)(=O)=O Show InChI InChI=1S/C18H20N2O6S/c1-18(17(21)19-22,27(2,25)26)12-11-13-3-5-14(6-4-13)15-7-9-16(10-8-15)20(23)24/h3-10,22H,11-12H2,1-2H3,(H,19,21)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.120	n/a	n/a	n/a	n/a	8.0	n/a
Pfizer Inc. US Patent					Assay Description IC50 determination in the LpxC enzyme assay was carried out in a similar manner to that described by Malikzay et al in the 2006 Poster, Screening Lpx...				US Patent US8853258 (2014) BindingDB Entry DOI: 10.7270/Q25M64DP
					More data for this Ligand-Target Pair
UDP-3-O-acyl-N-acetylglucosamine deacetylase (Pseudomonas aeruginosa)	BDBM135494 (US8853258, 104) Show SMILES CC(CCc1ccc(cc1)-c1ccc(F)c(Cl)c1)(C(=O)NO)S(C)(=O)=O Show InChI InChI=1S/C18H19ClFNO4S/c1-18(17(22)21-23,26(2,24)25)10-9-12-3-5-13(6-4-12)14-7-8-16(20)15(19)11-14/h3-8,11,23H,9-10H2,1-2H3,(H,21,22)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.127	n/a	n/a	n/a	n/a	8.0	n/a
Pfizer Inc. US Patent					Assay Description IC50 determination in the LpxC enzyme assay was carried out in a similar manner to that described by Malikzay et al in the 2006 Poster, Screening Lpx...				US Patent US8853258 (2014) BindingDB Entry DOI: 10.7270/Q25M64DP
					More data for this Ligand-Target Pair
UDP-3-O-acyl-N-acetylglucosamine deacetylase (Pseudomonas aeruginosa)	BDBM135478 (US8853258, 47) Show SMILES CC(CCc1ccc(cc1)-c1ccc(CCCO)cc1)(C(=O)NO)S(C)(=O)=O Show InChI InChI=1S/C21H27NO5S/c1-21(20(24)22-25,28(2,26)27)14-13-17-7-11-19(12-8-17)18-9-5-16(6-10-18)4-3-15-23/h5-12,23,25H,3-4,13-15H2,1-2H3,(H,22,24)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.132	n/a	n/a	n/a	n/a	8.0	n/a
Pfizer Inc. US Patent					Assay Description IC50 determination in the LpxC enzyme assay was carried out in a similar manner to that described by Malikzay et al in the 2006 Poster, Screening Lpx...				US Patent US8853258 (2014) BindingDB Entry DOI: 10.7270/Q25M64DP
					More data for this Ligand-Target Pair
UDP-3-O-acyl-N-acetylglucosamine deacetylase (Pseudomonas aeruginosa)	BDBM135495 (US8853258, 107) Show SMILES C[C@@](CCc1ccc(cc1)-c1ccc(cc1)C#N)(C(=O)NO)S(C)(=O)=O Show InChI InChI=1S/C19H20N2O4S/c1-19(18(22)21-23,26(2,24)25)12-11-14-3-7-16(8-4-14)17-9-5-15(13-20)6-10-17/h3-10,23H,11-12H2,1-2H3,(H,21,22)/t19-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.134	n/a	n/a	n/a	n/a	8.0	n/a
Pfizer Inc. US Patent					Assay Description IC50 determination in the LpxC enzyme assay was carried out in a similar manner to that described by Malikzay et al in the 2006 Poster, Screening Lpx...				US Patent US8853258 (2014) BindingDB Entry DOI: 10.7270/Q25M64DP
					More data for this Ligand-Target Pair
UDP-3-O-acyl-N-acetylglucosamine deacetylase (Pseudomonas aeruginosa)	BDBM135530 (US8853258, 181) Show SMILES CC(=O)c1ccc(cc1O)-c1ccc(CCC(C)(C(=O)NO)S(C)(=O)=O)cc1 Show InChI InChI=1S/C20H23NO6S/c1-13(22)17-9-8-16(12-18(17)23)15-6-4-14(5-7-15)10-11-20(2,19(24)21-25)28(3,26)27/h4-9,12,23,25H,10-11H2,1-3H3,(H,21,24)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.138	n/a	n/a	n/a	n/a	8.0	n/a
Pfizer Inc. US Patent					Assay Description IC50 determination in the LpxC enzyme assay was carried out in a similar manner to that described by Malikzay et al in the 2006 Poster, Screening Lpx...				US Patent US8853258 (2014) BindingDB Entry DOI: 10.7270/Q25M64DP
					More data for this Ligand-Target Pair
UDP-3-O-acyl-N-acetylglucosamine deacetylase (Pseudomonas aeruginosa)	BDBM135497 (US8853258, 109) Show SMILES Cc1cc(ccc1C#N)-c1ccc(CCC(C)(C(=O)NO)S(C)(=O)=O)cc1 Show InChI InChI=1S/C20H22N2O4S/c1-14-12-17(8-9-18(14)13-21)16-6-4-15(5-7-16)10-11-20(2,19(23)22-24)27(3,25)26/h4-9,12,24H,10-11H2,1-3H3,(H,22,23)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.144	n/a	n/a	n/a	n/a	8.0	n/a
Pfizer Inc. US Patent					Assay Description IC50 determination in the LpxC enzyme assay was carried out in a similar manner to that described by Malikzay et al in the 2006 Poster, Screening Lpx...				US Patent US8853258 (2014) BindingDB Entry DOI: 10.7270/Q25M64DP
					More data for this Ligand-Target Pair
UDP-3-O-acyl-N-acetylglucosamine deacetylase (Pseudomonas aeruginosa)	BDBM135498 (US8853258, 113) Show SMILES CC(CCc1ccc(cc1)-c1ccc(OCCO)cc1)(C(=O)NO)S(C)(=O)=O Show InChI InChI=1S/C20H25NO6S/c1-20(19(23)21-24,28(2,25)26)12-11-15-3-5-16(6-4-15)17-7-9-18(10-8-17)27-14-13-22/h3-10,22,24H,11-14H2,1-2H3,(H,21,23)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.148	n/a	n/a	n/a	n/a	8.0	n/a
Pfizer Inc. US Patent					Assay Description IC50 determination in the LpxC enzyme assay was carried out in a similar manner to that described by Malikzay et al in the 2006 Poster, Screening Lpx...				US Patent US8853258 (2014) BindingDB Entry DOI: 10.7270/Q25M64DP
					More data for this Ligand-Target Pair
UDP-3-O-acyl-N-acetylglucosamine deacetylase (Pseudomonas aeruginosa)	BDBM135502 (US8853258, 127) Show SMILES CC(CCc1ccc(cc1)-c1cc(F)c(C#N)c(F)c1)(C(=O)NO)S(C)(=O)=O Show InChI InChI=1S/C19H18F2N2O4S/c1-19(18(24)23-25,28(2,26)27)8-7-12-3-5-13(6-4-12)14-9-16(20)15(11-22)17(21)10-14/h3-6,9-10,25H,7-8H2,1-2H3,(H,23,24)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.150	n/a	n/a	n/a	n/a	8.0	n/a
Pfizer Inc. US Patent					Assay Description IC50 determination in the LpxC enzyme assay was carried out in a similar manner to that described by Malikzay et al in the 2006 Poster, Screening Lpx...				US Patent US8853258 (2014) BindingDB Entry DOI: 10.7270/Q25M64DP
					More data for this Ligand-Target Pair
UDP-3-O-acyl-N-acetylglucosamine deacetylase (Pseudomonas aeruginosa)	BDBM135533 (US8853258, 184) Show SMILES CC(=O)c1ccc(cc1F)-c1ccc(CCC(C)(C(=O)NO)S(C)(=O)=O)cc1 Show InChI InChI=1S/C20H22FNO5S/c1-13(23)17-9-8-16(12-18(17)21)15-6-4-14(5-7-15)10-11-20(2,19(24)22-25)28(3,26)27/h4-9,12,25H,10-11H2,1-3H3,(H,22,24)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.155	n/a	n/a	n/a	n/a	8.0	n/a
Pfizer Inc. US Patent					Assay Description IC50 determination in the LpxC enzyme assay was carried out in a similar manner to that described by Malikzay et al in the 2006 Poster, Screening Lpx...				US Patent US8853258 (2014) BindingDB Entry DOI: 10.7270/Q25M64DP
					More data for this Ligand-Target Pair
UDP-3-O-acyl-N-acetylglucosamine deacetylase (Pseudomonas aeruginosa)	BDBM135528 (US8853258, 179) Show SMILES C[C@@](CCc1ccc(cc1)-c1ccc(OCCCN2CCOCC2)cc1)(C(=O)NO)S(C)(=O)=O Show InChI InChI=1S/C25H34N2O6S/c1-25(24(28)26-29,34(2,30)31)13-12-20-4-6-21(7-5-20)22-8-10-23(11-9-22)33-17-3-14-27-15-18-32-19-16-27/h4-11,29H,3,12-19H2,1-2H3,(H,26,28)/t25-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid PDB UniChem Similars	PDB US Patent	n/a	n/a	0.172	n/a	n/a	n/a	n/a	8.0	n/a
Pfizer Inc. US Patent					Assay Description IC50 determination in the LpxC enzyme assay was carried out in a similar manner to that described by Malikzay et al in the 2006 Poster, Screening Lpx...				US Patent US8853258 (2014) BindingDB Entry DOI: 10.7270/Q25M64DP
					More data for this Ligand-Target Pair				3D Structure (crystal)
UDP-3-O-acyl-N-acetylglucosamine deacetylase (Pseudomonas aeruginosa)	BDBM135496 (US8853258, 108) Show SMILES CC(=O)c1ccc(cc1)-c1ccc(CCC(C)(C(=O)NO)S(C)(=O)=O)cc1 Show InChI InChI=1S/C20H23NO5S/c1-14(22)16-8-10-18(11-9-16)17-6-4-15(5-7-17)12-13-20(2,19(23)21-24)27(3,25)26/h4-11,24H,12-13H2,1-3H3,(H,21,23)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.176	n/a	n/a	n/a	n/a	8.0	n/a
Pfizer Inc. US Patent					Assay Description IC50 determination in the LpxC enzyme assay was carried out in a similar manner to that described by Malikzay et al in the 2006 Poster, Screening Lpx...				US Patent US8853258 (2014) BindingDB Entry DOI: 10.7270/Q25M64DP
					More data for this Ligand-Target Pair
UDP-3-O-acyl-N-acetylglucosamine deacetylase (Pseudomonas aeruginosa)	BDBM135472 (US8853258, 23) Show SMILES C[C@@](CCc1ccc(cc1)-c1ccc(O)cc1)(C(=O)NO)S(C)(=O)=O |r| Show InChI InChI=1S/C18H21NO5S/c1-18(17(21)19-22,25(2,23)24)12-11-13-3-5-14(6-4-13)15-7-9-16(20)10-8-15/h3-10,20,22H,11-12H2,1-2H3,(H,19,21)/t18-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.180	n/a	n/a	n/a	n/a	8.0	n/a
Pfizer Inc. US Patent					Assay Description IC50 determination in the LpxC enzyme assay was carried out in a similar manner to that described by Malikzay et al in the 2006 Poster, Screening Lpx...				US Patent US8853258 (2014) BindingDB Entry DOI: 10.7270/Q25M64DP
					More data for this Ligand-Target Pair
UDP-3-O-acyl-N-acetylglucosamine deacetylase (Pseudomonas aeruginosa)	BDBM135484 (US8853258, 62) Show SMILES CC(CCc1ccc(cc1)-c1cccc(F)c1F)(C(=O)NO)S(C)(=O)=O Show InChI InChI=1S/C18H19F2NO4S/c1-18(17(22)21-23,26(2,24)25)11-10-12-6-8-13(9-7-12)14-4-3-5-15(19)16(14)20/h3-9,23H,10-11H2,1-2H3,(H,21,22)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.185	n/a	n/a	n/a	n/a	8.0	n/a
Pfizer Inc. US Patent					Assay Description IC50 determination in the LpxC enzyme assay was carried out in a similar manner to that described by Malikzay et al in the 2006 Poster, Screening Lpx...				US Patent US8853258 (2014) BindingDB Entry DOI: 10.7270/Q25M64DP
					More data for this Ligand-Target Pair
UDP-3-O-acyl-N-acetylglucosamine deacetylase (Pseudomonas aeruginosa)	BDBM30550 (US8853258, 194) Show SMILES CC(O)C(=O)c1ccc(cc1)-c1ccc(CCC(C)(C(=O)NO)S(C)(=O)=O)cc1 Show InChI InChI=1S/C22H16N4O4S/c23-20-18(31(28,29)16-8-2-1-3-9-16)13-17-21(26(20)14-15-7-6-12-30-15)24-19-10-4-5-11-25(19)22(17)27/h1-13,23H,14H2/b23-20+	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.195	n/a	n/a	n/a	n/a	8.0	n/a
Pfizer Inc. US Patent					Assay Description IC50 determination in the LpxC enzyme assay was carried out in a similar manner to that described by Malikzay et al in the 2006 Poster, Screening Lpx...				US Patent US8853258 (2014) BindingDB Entry DOI: 10.7270/Q25M64DP
					More data for this Ligand-Target Pair
UDP-3-O-acyl-N-acetylglucosamine deacetylase (Pseudomonas aeruginosa)	BDBM135518 (US8853258, 169) Show SMILES CC(CCc1ccc(cc1)-c1ccc(cc1)C(=O)CO)(C(=O)NO)S(C)(=O)=O Show InChI InChI=1S/C20H23NO6S/c1-20(19(24)21-25,28(2,26)27)12-11-14-3-5-15(6-4-14)16-7-9-17(10-8-16)18(23)13-22/h3-10,22,25H,11-13H2,1-2H3,(H,21,24)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.200	n/a	n/a	n/a	n/a	8.0	n/a
Pfizer Inc. US Patent					Assay Description IC50 determination in the LpxC enzyme assay was carried out in a similar manner to that described by Malikzay et al in the 2006 Poster, Screening Lpx...				US Patent US8853258 (2014) BindingDB Entry DOI: 10.7270/Q25M64DP
					More data for this Ligand-Target Pair
UDP-3-O-acyl-N-acetylglucosamine deacetylase (Pseudomonas aeruginosa)	BDBM135506 (US8853258, 136) Show SMILES CC(CCc1ccc(cc1)-c1ccc(OCCCCO)cc1)(C(=O)NO)S(C)(=O)=O Show InChI InChI=1S/C22H29NO6S/c1-22(21(25)23-26,30(2,27)28)14-13-17-5-7-18(8-6-17)19-9-11-20(12-10-19)29-16-4-3-15-24/h5-12,24,26H,3-4,13-16H2,1-2H3,(H,23,25)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.205	n/a	n/a	n/a	n/a	8.0	n/a
Pfizer Inc. US Patent					Assay Description IC50 determination in the LpxC enzyme assay was carried out in a similar manner to that described by Malikzay et al in the 2006 Poster, Screening Lpx...				US Patent US8853258 (2014) BindingDB Entry DOI: 10.7270/Q25M64DP
					More data for this Ligand-Target Pair
UDP-3-O-acyl-N-acetylglucosamine deacetylase (Pseudomonas aeruginosa)	BDBM135483 (US8853258, 59) Show SMILES CC(CCc1ccc(cc1)-c1cccc(Cl)c1Cl)(C(=O)NO)S(C)(=O)=O Show InChI InChI=1S/C18H19Cl2NO4S/c1-18(17(22)21-23,26(2,24)25)11-10-12-6-8-13(9-7-12)14-4-3-5-15(19)16(14)20/h3-9,23H,10-11H2,1-2H3,(H,21,22)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.213	n/a	n/a	n/a	n/a	8.0	n/a
Pfizer Inc. US Patent					Assay Description IC50 determination in the LpxC enzyme assay was carried out in a similar manner to that described by Malikzay et al in the 2006 Poster, Screening Lpx...				US Patent US8853258 (2014) BindingDB Entry DOI: 10.7270/Q25M64DP
					More data for this Ligand-Target Pair
UDP-3-O-acyl-N-acetylglucosamine deacetylase (Pseudomonas aeruginosa)	BDBM135503 (US8853258, 128) Show SMILES CC(CCc1ccc(cc1)-c1ccc(cc1F)C#N)(C(=O)NO)S(C)(=O)=O Show InChI InChI=1S/C19H19FN2O4S/c1-19(18(23)22-24,27(2,25)26)10-9-13-3-6-15(7-4-13)16-8-5-14(12-21)11-17(16)20/h3-8,11,24H,9-10H2,1-2H3,(H,22,23)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.232	n/a	n/a	n/a	n/a	8.0	n/a
Pfizer Inc. US Patent					Assay Description IC50 determination in the LpxC enzyme assay was carried out in a similar manner to that described by Malikzay et al in the 2006 Poster, Screening Lpx...				US Patent US8853258 (2014) BindingDB Entry DOI: 10.7270/Q25M64DP
					More data for this Ligand-Target Pair
UDP-3-O-acyl-N-acetylglucosamine deacetylase (Pseudomonas aeruginosa)	BDBM135516 (US8853258, 167) Show SMILES CC(CCc1ccc(c(F)c1)-c1ccc(F)cc1)(C(=O)NO)S(C)(=O)=O Show InChI InChI=1S/C18H19F2NO4S/c1-18(17(22)21-23,26(2,24)25)10-9-12-3-8-15(16(20)11-12)13-4-6-14(19)7-5-13/h3-8,11,23H,9-10H2,1-2H3,(H,21,22)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.235	n/a	n/a	n/a	n/a	8.0	n/a
Pfizer Inc. US Patent					Assay Description IC50 determination in the LpxC enzyme assay was carried out in a similar manner to that described by Malikzay et al in the 2006 Poster, Screening Lpx...				US Patent US8853258 (2014) BindingDB Entry DOI: 10.7270/Q25M64DP
					More data for this Ligand-Target Pair
UDP-3-O-acyl-N-acetylglucosamine deacetylase (Pseudomonas aeruginosa)	BDBM135560 (US8853258, 212) Show SMILES COc1ccc(cn1)-c1ccc(CC[C@](C)(C(=O)NO)S(C)(=O)=O)cc1 Show InChI InChI=1S/C18H22N2O5S/c1-18(17(21)20-22,26(3,23)24)11-10-13-4-6-14(7-5-13)15-8-9-16(25-2)19-12-15/h4-9,12,22H,10-11H2,1-3H3,(H,20,21)/t18-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.237	n/a	n/a	n/a	n/a	8.0	n/a
Pfizer Inc. US Patent					Assay Description IC50 determination in the LpxC enzyme assay was carried out in a similar manner to that described by Malikzay et al in the 2006 Poster, Screening Lpx...				US Patent US8853258 (2014) BindingDB Entry DOI: 10.7270/Q25M64DP
					More data for this Ligand-Target Pair
UDP-3-O-acyl-N-acetylglucosamine deacetylase (Pseudomonas aeruginosa)	BDBM135535 (US8853258, 186) Show SMILES C[C@@](CCc1ccc(cc1)-c1ccc(cc1)C(=O)CO)(C(=O)NO)S(C)(=O)=O Show InChI InChI=1S/C20H23NO6S/c1-20(19(24)21-25,28(2,26)27)12-11-14-3-5-15(6-4-14)16-7-9-17(10-8-16)18(23)13-22/h3-10,22,25H,11-13H2,1-2H3,(H,21,24)/t20-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.238	n/a	n/a	n/a	n/a	8.0	n/a
Pfizer Inc. US Patent					Assay Description IC50 determination in the LpxC enzyme assay was carried out in a similar manner to that described by Malikzay et al in the 2006 Poster, Screening Lpx...				US Patent US8853258 (2014) BindingDB Entry DOI: 10.7270/Q25M64DP
					More data for this Ligand-Target Pair
UDP-3-O-acyl-N-acetylglucosamine deacetylase (Pseudomonas aeruginosa)	BDBM135549 (US8853258, 201) Show SMILES C[C@@](CCc1ccc(cc1)-c1cnc2ccccc2c1)(C(=O)NO)S(C)(=O)=O Show InChI InChI=1S/C21H22N2O4S/c1-21(20(24)23-25,28(2,26)27)12-11-15-7-9-16(10-8-15)18-13-17-5-3-4-6-19(17)22-14-18/h3-10,13-14,25H,11-12H2,1-2H3,(H,23,24)/t21-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.240	n/a	n/a	n/a	n/a	8.0	n/a
Pfizer Inc. US Patent					Assay Description IC50 determination in the LpxC enzyme assay was carried out in a similar manner to that described by Malikzay et al in the 2006 Poster, Screening Lpx...				US Patent US8853258 (2014) BindingDB Entry DOI: 10.7270/Q25M64DP
					More data for this Ligand-Target Pair
UDP-3-O-acyl-N-acetylglucosamine deacetylase (Pseudomonas aeruginosa)	BDBM135513 (US8853258, 162) Show SMILES Cc1cc(CCC(C)(C(=O)NO)S(C)(=O)=O)ccc1-c1ccc(cc1)C#N Show InChI InChI=1S/C20H22N2O4S/c1-14-12-15(10-11-20(2,19(23)22-24)27(3,25)26)6-9-18(14)17-7-4-16(13-21)5-8-17/h4-9,12,24H,10-11H2,1-3H3,(H,22,23)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.241	n/a	n/a	n/a	n/a	8.0	n/a
Pfizer Inc. US Patent					Assay Description IC50 determination in the LpxC enzyme assay was carried out in a similar manner to that described by Malikzay et al in the 2006 Poster, Screening Lpx...				US Patent US8853258 (2014) BindingDB Entry DOI: 10.7270/Q25M64DP
					More data for this Ligand-Target Pair
UDP-3-O-acyl-N-acetylglucosamine deacetylase (Pseudomonas aeruginosa)	BDBM135490 (US8853258, 83) Show SMILES Cc1ccc(cc1C)-c1ccc(CCC(C)(C(=O)NO)S(C)(=O)=O)cc1 Show InChI InChI=1S/C20H25NO4S/c1-14-5-8-18(13-15(14)2)17-9-6-16(7-10-17)11-12-20(3,19(22)21-23)26(4,24)25/h5-10,13,23H,11-12H2,1-4H3,(H,21,22)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.242	n/a	n/a	n/a	n/a	8.0	n/a
Pfizer Inc. US Patent					Assay Description IC50 determination in the LpxC enzyme assay was carried out in a similar manner to that described by Malikzay et al in the 2006 Poster, Screening Lpx...				US Patent US8853258 (2014) BindingDB Entry DOI: 10.7270/Q25M64DP
					More data for this Ligand-Target Pair
UDP-3-O-acyl-N-acetylglucosamine deacetylase (Pseudomonas aeruginosa)	BDBM135539 (US8853258, 190) Show SMILES CC(=O)c1ccc(cn1)-c1ccc(CC[C@](C)(C(=O)NO)S(C)(=O)=O)cc1 Show InChI InChI=1S/C19H22N2O5S/c1-13(22)17-9-8-16(12-20-17)15-6-4-14(5-7-15)10-11-19(2,18(23)21-24)27(3,25)26/h4-9,12,24H,10-11H2,1-3H3,(H,21,23)/t19-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.246	n/a	n/a	n/a	n/a	8.0	n/a
Pfizer Inc. US Patent					Assay Description IC50 determination in the LpxC enzyme assay was carried out in a similar manner to that described by Malikzay et al in the 2006 Poster, Screening Lpx...				US Patent US8853258 (2014) BindingDB Entry DOI: 10.7270/Q25M64DP
					More data for this Ligand-Target Pair
UDP-3-O-acyl-N-acetylglucosamine deacetylase (Pseudomonas aeruginosa)	BDBM135459 (US8853258, 2) Show SMILES CC(CCc1ccc(cc1F)-c1ccccc1)(C(=O)NO)S(C)(=O)=O Show InChI InChI=1S/C18H20FNO4S/c1-18(17(21)20-22,25(2,23)24)11-10-14-8-9-15(12-16(14)19)13-6-4-3-5-7-13/h3-9,12,22H,10-11H2,1-2H3,(H,20,21)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.260	n/a	n/a	n/a	n/a	8.0	n/a
Pfizer Inc. US Patent					Assay Description IC50 determination in the LpxC enzyme assay was carried out in a similar manner to that described by Malikzay et al in the 2006 Poster, Screening Lpx...				US Patent US8853258 (2014) BindingDB Entry DOI: 10.7270/Q25M64DP
					More data for this Ligand-Target Pair
UDP-3-O-acyl-N-acetylglucosamine deacetylase (Pseudomonas aeruginosa)	BDBM135547 (US8853258, 199) Show SMILES C[C@@](CCc1ccc(cc1)-c1ccc2C(=O)NCc2c1)(C(=O)NO)S(C)(=O)=O Show InChI InChI=1S/C20H22N2O5S/c1-20(19(24)22-25,28(2,26)27)10-9-13-3-5-14(6-4-13)15-7-8-17-16(11-15)12-21-18(17)23/h3-8,11,25H,9-10,12H2,1-2H3,(H,21,23)(H,22,24)/t20-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.266	n/a	n/a	n/a	n/a	8.0	n/a
Pfizer Inc. US Patent					Assay Description IC50 determination in the LpxC enzyme assay was carried out in a similar manner to that described by Malikzay et al in the 2006 Poster, Screening Lpx...				US Patent US8853258 (2014) BindingDB Entry DOI: 10.7270/Q25M64DP
					More data for this Ligand-Target Pair
UDP-3-O-acyl-N-acetylglucosamine deacetylase (Pseudomonas aeruginosa)	BDBM135492 (US8853258, 91) Show SMILES Cc1cc(ccc1-c1ccc(CCC(C)(C(=O)NO)S(C)(=O)=O)cc1)C#N Show InChI InChI=1S/C20H22N2O4S/c1-14-12-16(13-21)6-9-18(14)17-7-4-15(5-8-17)10-11-20(2,19(23)22-24)27(3,25)26/h4-9,12,24H,10-11H2,1-3H3,(H,22,23)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.266	n/a	n/a	n/a	n/a	8.0	n/a
Pfizer Inc. US Patent					Assay Description IC50 determination in the LpxC enzyme assay was carried out in a similar manner to that described by Malikzay et al in the 2006 Poster, Screening Lpx...				US Patent US8853258 (2014) BindingDB Entry DOI: 10.7270/Q25M64DP
					More data for this Ligand-Target Pair
UDP-3-O-acyl-N-acetylglucosamine deacetylase (Pseudomonas aeruginosa)	BDBM135564 (US8853258, 217) Show SMILES CC(C)(O)C(=O)c1ccc(cc1)-c1ccc(CC[C@](C)(C(=O)NO)S(C)(=O)=O)cc1 Show InChI InChI=1S/C22H27NO6S/c1-21(2,26)19(24)18-11-9-17(10-12-18)16-7-5-15(6-8-16)13-14-22(3,20(25)23-27)30(4,28)29/h5-12,26-27H,13-14H2,1-4H3,(H,23,25)/t22-/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.278	n/a	n/a	n/a	n/a	8.0	n/a
Pfizer Inc. US Patent					Assay Description IC50 determination in the LpxC enzyme assay was carried out in a similar manner to that described by Malikzay et al in the 2006 Poster, Screening Lpx...				US Patent US8853258 (2014) BindingDB Entry DOI: 10.7270/Q25M64DP
					More data for this Ligand-Target Pair
UDP-3-O-acyl-N-acetylglucosamine deacetylase (Pseudomonas aeruginosa)	BDBM135465 (US8853258, 13) Show SMILES CC(CCc1ccc(cc1)C1=CCCCCC1)(C(=O)NO)S(C)(=O)=O |t:11| Show InChI InChI=1S/C19H27NO4S/c1-19(18(21)20-22,25(2,23)24)14-13-15-9-11-17(12-10-15)16-7-5-3-4-6-8-16/h7,9-12,22H,3-6,8,13-14H2,1-2H3,(H,20,21)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.290	n/a	n/a	n/a	n/a	8.0	n/a
Pfizer Inc. US Patent					Assay Description IC50 determination in the LpxC enzyme assay was carried out in a similar manner to that described by Malikzay et al in the 2006 Poster, Screening Lpx...				US Patent US8853258 (2014) BindingDB Entry DOI: 10.7270/Q25M64DP
					More data for this Ligand-Target Pair
UDP-3-O-acyl-N-acetylglucosamine deacetylase (Pseudomonas aeruginosa)	BDBM135482 (US8853258, 57) Show SMILES CC(CCc1ccc(cc1)-c1ccc2[nH]ccc2c1)(C(=O)NO)S(C)(=O)=O Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.295	n/a	n/a	n/a	n/a	8.0	n/a
Pfizer Inc. US Patent					Assay Description IC50 determination in the LpxC enzyme assay was carried out in a similar manner to that described by Malikzay et al in the 2006 Poster, Screening Lpx...				US Patent US8853258 (2014) BindingDB Entry DOI: 10.7270/Q25M64DP
					More data for this Ligand-Target Pair
UDP-3-O-acyl-N-acetylglucosamine deacetylase (Pseudomonas aeruginosa)	BDBM135514 (US8853258, 165) Show SMILES CC(CCc1ccc(cc1)-c1ccc(cc1)N1CCOCC1)(C(=O)NO)S(C)(=O)=O Show InChI InChI=1S/C22H28N2O5S/c1-22(21(25)23-26,30(2,27)28)12-11-17-3-5-18(6-4-17)19-7-9-20(10-8-19)24-13-15-29-16-14-24/h3-10,26H,11-16H2,1-2H3,(H,23,25)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.295	n/a	n/a	n/a	n/a	8.0	n/a
Pfizer Inc. US Patent					Assay Description IC50 determination in the LpxC enzyme assay was carried out in a similar manner to that described by Malikzay et al in the 2006 Poster, Screening Lpx...				US Patent US8853258 (2014) BindingDB Entry DOI: 10.7270/Q25M64DP
					More data for this Ligand-Target Pair
UDP-3-O-acyl-N-acetylglucosamine deacetylase (Pseudomonas aeruginosa)	BDBM135526 (US8853258, 177) Show SMILES CC(CCc1ccc(c(F)c1)-c1ccc(O)cc1)(C(=O)NO)S(C)(=O)=O Show InChI InChI=1S/C18H20FNO5S/c1-18(17(22)20-23,26(2,24)25)10-9-12-3-8-15(16(19)11-12)13-4-6-14(21)7-5-13/h3-8,11,21,23H,9-10H2,1-2H3,(H,20,22)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.306	n/a	n/a	n/a	n/a	8.0	n/a
Pfizer Inc. US Patent					Assay Description IC50 determination in the LpxC enzyme assay was carried out in a similar manner to that described by Malikzay et al in the 2006 Poster, Screening Lpx...				US Patent US8853258 (2014) BindingDB Entry DOI: 10.7270/Q25M64DP
					More data for this Ligand-Target Pair
UDP-3-O-acyl-N-acetylglucosamine deacetylase (Pseudomonas aeruginosa)	BDBM135462 (US8853258, 7) Show SMILES CC(C)(CCc1ccc(cc1)-c1ccccc1)C(=O)NO Show InChI InChI=1S/C18H21NO2/c1-18(2,17(20)19-21)13-12-14-8-10-16(11-9-14)15-6-4-3-5-7-15/h3-11,21H,12-13H2,1-2H3,(H,19,20)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.310	n/a	n/a	n/a	n/a	8.0	n/a
Pfizer Inc. US Patent					Assay Description IC50 determination in the LpxC enzyme assay was carried out in a similar manner to that described by Malikzay et al in the 2006 Poster, Screening Lpx...				US Patent US8853258 (2014) BindingDB Entry DOI: 10.7270/Q25M64DP
					More data for this Ligand-Target Pair
UDP-3-O-acyl-N-acetylglucosamine deacetylase (Pseudomonas aeruginosa)	BDBM135463 (US8853258, 9) Show SMILES CC(CCc1ccc(cc1)-c1ccc(cc1)-c1cc(CO)no1)(C(=O)NO)S(C)(=O)=O Show InChI InChI=1S/C22H24N2O6S/c1-22(21(26)23-27,31(2,28)29)12-11-15-3-5-16(6-4-15)17-7-9-18(10-8-17)20-13-19(14-25)24-30-20/h3-10,13,25,27H,11-12,14H2,1-2H3,(H,23,26)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.320	n/a	n/a	n/a	n/a	8.0	n/a
Pfizer Inc. US Patent					Assay Description IC50 determination in the LpxC enzyme assay was carried out in a similar manner to that described by Malikzay et al in the 2006 Poster, Screening Lpx...				US Patent US8853258 (2014) BindingDB Entry DOI: 10.7270/Q25M64DP
					More data for this Ligand-Target Pair
UDP-3-O-acyl-N-acetylglucosamine deacetylase (Pseudomonas aeruginosa)	BDBM135573 (US8853258, 226) Show SMILES CC(CCc1ccc(cc1)C1=CCSCC1)(C(=O)NO)S(C)(=O)=O |t:11| Show InChI InChI=1S/C17H23NO4S2/c1-17(16(19)18-20,24(2,21)22)10-7-13-3-5-14(6-4-13)15-8-11-23-12-9-15/h3-6,8,20H,7,9-12H2,1-2H3,(H,18,19)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.320	n/a	n/a	n/a	n/a	8.0	n/a
Pfizer Inc. US Patent					Assay Description IC50 determination in the LpxC enzyme assay was carried out in a similar manner to that described by Malikzay et al in the 2006 Poster, Screening Lpx...				US Patent US8853258 (2014) BindingDB Entry DOI: 10.7270/Q25M64DP
					More data for this Ligand-Target Pair
UDP-3-O-acyl-N-acetylglucosamine deacetylase (Pseudomonas aeruginosa)	BDBM30560 (US8853258, 247) Show SMILES CC(CCc1ccc(Oc2cccc(F)c2F)cc1)(C(=O)NO)S(C)(=O)=O Show InChI InChI=1S/C22H20FN3O.C2H2O4/c1-26-20(15-7-10-17(23)11-8-15)14-25-22(26)24-13-16-9-12-21(27-2)19-6-4-3-5-18(16)19;3-1(4)2(5)6/h3-12,14H,13H2,1-2H3,(H,24,25);(H,3,4)(H,5,6)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.325	n/a	n/a	n/a	n/a	8.0	n/a
Pfizer Inc. US Patent					Assay Description IC50 determination in the LpxC enzyme assay was carried out in a similar manner to that described by Malikzay et al in the 2006 Poster, Screening Lpx...				US Patent US8853258 (2014) BindingDB Entry DOI: 10.7270/Q25M64DP
					More data for this Ligand-Target Pair
UDP-3-O-acyl-N-acetylglucosamine deacetylase (Pseudomonas aeruginosa)	BDBM135501 (US8853258, 126) Show SMILES CC(CCc1ccc(cc1)-c1ccc(C#N)c(Cl)c1)(C(=O)NO)S(C)(=O)=O Show InChI InChI=1S/C19H19ClN2O4S/c1-19(18(23)22-24,27(2,25)26)10-9-13-3-5-14(6-4-13)15-7-8-16(12-21)17(20)11-15/h3-8,11,24H,9-10H2,1-2H3,(H,22,23)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.329	n/a	n/a	n/a	n/a	8.0	n/a
Pfizer Inc. US Patent					Assay Description IC50 determination in the LpxC enzyme assay was carried out in a similar manner to that described by Malikzay et al in the 2006 Poster, Screening Lpx...				US Patent US8853258 (2014) BindingDB Entry DOI: 10.7270/Q25M64DP
					More data for this Ligand-Target Pair
UDP-3-O-acyl-N-acetylglucosamine deacetylase (Pseudomonas aeruginosa)	BDBM135474 (US8853258, 34) Show SMILES CC(CCc1ccc(cc1)-c1ccc(CCO)cc1)(C(=O)NO)S(C)(=O)=O Show InChI InChI=1S/C20H25NO5S/c1-20(19(23)21-24,27(2,25)26)13-11-15-3-7-17(8-4-15)18-9-5-16(6-10-18)12-14-22/h3-10,22,24H,11-14H2,1-2H3,(H,21,23)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.331	n/a	n/a	n/a	n/a	8.0	n/a
Pfizer Inc. US Patent					Assay Description IC50 determination in the LpxC enzyme assay was carried out in a similar manner to that described by Malikzay et al in the 2006 Poster, Screening Lpx...				US Patent US8853258 (2014) BindingDB Entry DOI: 10.7270/Q25M64DP
					More data for this Ligand-Target Pair
UDP-3-O-acyl-N-acetylglucosamine deacetylase (Pseudomonas aeruginosa)	BDBM135476 (US8853258, 42) Show SMILES CC(CCc1ccc(cc1)-c1cccc(F)c1)(C(=O)NO)S(C)(=O)=O Show InChI InChI=1S/C18H20FNO4S/c1-18(17(21)20-22,25(2,23)24)11-10-13-6-8-14(9-7-13)15-4-3-5-16(19)12-15/h3-9,12,22H,10-11H2,1-2H3,(H,20,21)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.335	n/a	n/a	n/a	n/a	8.0	n/a
Pfizer Inc. US Patent					Assay Description IC50 determination in the LpxC enzyme assay was carried out in a similar manner to that described by Malikzay et al in the 2006 Poster, Screening Lpx...				US Patent US8853258 (2014) BindingDB Entry DOI: 10.7270/Q25M64DP
					More data for this Ligand-Target Pair
UDP-3-O-acyl-N-acetylglucosamine deacetylase (Pseudomonas aeruginosa)	BDBM135507 (US8853258, 138) Show SMILES CC(CCc1ccc(cc1)-c1ccc(O)c(F)c1)(C(=O)NO)S(C)(=O)=O Show InChI InChI=1S/C18H20FNO5S/c1-18(17(22)20-23,26(2,24)25)10-9-12-3-5-13(6-4-12)14-7-8-16(21)15(19)11-14/h3-8,11,21,23H,9-10H2,1-2H3,(H,20,22)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.335	n/a	n/a	n/a	n/a	8.0	n/a
Pfizer Inc. US Patent					Assay Description IC50 determination in the LpxC enzyme assay was carried out in a similar manner to that described by Malikzay et al in the 2006 Poster, Screening Lpx...				US Patent US8853258 (2014) BindingDB Entry DOI: 10.7270/Q25M64DP
					More data for this Ligand-Target Pair
UDP-3-O-acyl-N-acetylglucosamine deacetylase (Pseudomonas aeruginosa)	BDBM135508 (US8853258, 157) Show SMILES Cc1cc(ccc1CCC(C)(C(=O)NO)S(C)(=O)=O)-c1ccc(F)cc1 Show InChI InChI=1S/C19H22FNO4S/c1-13-12-16(15-6-8-17(20)9-7-15)5-4-14(13)10-11-19(2,18(22)21-23)26(3,24)25/h4-9,12,23H,10-11H2,1-3H3,(H,21,22)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.337	n/a	n/a	n/a	n/a	8.0	n/a
Pfizer Inc. US Patent					Assay Description IC50 determination in the LpxC enzyme assay was carried out in a similar manner to that described by Malikzay et al in the 2006 Poster, Screening Lpx...				US Patent US8853258 (2014) BindingDB Entry DOI: 10.7270/Q25M64DP
					More data for this Ligand-Target Pair
UDP-3-O-acyl-N-acetylglucosamine deacetylase (Pseudomonas aeruginosa)	BDBM135537 (US8853258, 188) Show SMILES CC(=O)c1ccc(cn1)-c1ccc(CCC(C)(C(=O)NO)S(C)(=O)=O)c(F)c1 Show InChI InChI=1S/C19H21FN2O5S/c1-12(23)17-7-6-15(11-21-17)14-5-4-13(16(20)10-14)8-9-19(2,18(24)22-25)28(3,26)27/h4-7,10-11,25H,8-9H2,1-3H3,(H,22,24)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.348	n/a	n/a	n/a	n/a	8.0	n/a
Pfizer Inc. US Patent					Assay Description IC50 determination in the LpxC enzyme assay was carried out in a similar manner to that described by Malikzay et al in the 2006 Poster, Screening Lpx...				US Patent US8853258 (2014) BindingDB Entry DOI: 10.7270/Q25M64DP
					More data for this Ligand-Target Pair
UDP-3-O-acyl-N-acetylglucosamine deacetylase (Pseudomonas aeruginosa)	BDBM135485 (US8853258, 63) Show SMILES CC(C)Cc1ccc(cc1)-c1ccc(CCC(C)(C(=O)NO)S(C)(=O)=O)cc1 Show InChI InChI=1S/C22H29NO4S/c1-16(2)15-18-7-11-20(12-8-18)19-9-5-17(6-10-19)13-14-22(3,21(24)23-25)28(4,26)27/h5-12,16,25H,13-15H2,1-4H3,(H,23,24)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.356	n/a	n/a	n/a	n/a	8.0	n/a
Pfizer Inc. US Patent					Assay Description IC50 determination in the LpxC enzyme assay was carried out in a similar manner to that described by Malikzay et al in the 2006 Poster, Screening Lpx...				US Patent US8853258 (2014) BindingDB Entry DOI: 10.7270/Q25M64DP
					More data for this Ligand-Target Pair

Displayed 1 to 50 (of 197 total )  |  Next  |  Last  >>

Jump to: