Compile Data Set for Download or QSAR

Found 195 hits of ph data with Target = 'Histone deacetylase 4'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 4 (Homo sapiens (Human))	BDBM36483 ((S)-6-acetamido-2-(2-((S)-2-acetamido-4-methylpent...) Show SMILES CC(C)C[C@H](NC(C)=O)C(=O)NCC(=O)N[C@@H](CCCCNC(C)=O)C(=O)Nc1ccc2c(C)cc(=O)oc2c1 Show InChI InChI=1S/C28H39N5O7/c1-16(2)12-23(31-19(5)35)27(38)30-15-25(36)33-22(8-6-7-11-29-18(4)34)28(39)32-20-9-10-21-17(3)13-26(37)40-24(21)14-20/h9-10,13-14,16,22-23H,6-8,11-12,15H2,1-5H3,(H,29,34)(H,30,38)(H,31,35)(H,32,39)(H,33,36)/t22-,23-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.18E+3	n/a	n/a	n/a	n/a	7.4	0
Dana-Farber Cancer Institute					Assay Description For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...				Nat Chem Biol 6: 238-243 (2010) Article DOI: 10.1038/nchembio.313 BindingDB Entry DOI: 10.7270/Q2C53J66
					More data for this Ligand-Target Pair
Histone deacetylase 4 (Homo sapiens (Human))	BDBM36484 ((S)-Benzyl (6-acetamido-1-((4-methyl-2-oxo-2H-chro...) Show SMILES CC(=O)NCCCC[C@H](NC(=O)OCc1ccccc1)C(=O)Nc1ccc2c(C)cc(=O)oc2c1 Show InChI InChI=1S/C26H29N3O6/c1-17-14-24(31)35-23-15-20(11-12-21(17)23)28-25(32)22(10-6-7-13-27-18(2)30)29-26(33)34-16-19-8-4-3-5-9-19/h3-5,8-9,11-12,14-15,22H,6-7,10,13,16H2,1-2H3,(H,27,30)(H,28,32)(H,29,33)/t22-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	643	n/a	n/a	n/a	n/a	7.4	0
Dana-Farber Cancer Institute					Assay Description For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...				Nat Chem Biol 6: 238-243 (2010) Article DOI: 10.1038/nchembio.313 BindingDB Entry DOI: 10.7270/Q2C53J66
					More data for this Ligand-Target Pair
Histone deacetylase 4 (Homo sapiens (Human))	BDBM29589 (Faridak | LBH-589 | LBH-589B | Panobinostat | US10...) Show SMILES Cc1[nH]c2ccccc2c1CCNCc1ccc(\C=C\C(=O)NO)cc1 Show InChI InChI=1S/C21H23N3O2/c1-15-18(19-4-2-3-5-20(19)23-15)12-13-22-14-17-8-6-16(7-9-17)10-11-21(25)24-26/h2-11,22-23,26H,12-14H2,1H3,(H,24,25)/b11-10+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	373	n/a	n/a	n/a	n/a	7.4	25
Broad Institute of Harvard and MIT					Assay Description Purified HDAC1-9 (0.5~5 nM) were incubated with 2 μM carboxyfluorescein (FAM)-labeled acetylated peptide substrate A or B and test compound for ...				ACS Chem Biol 11: 363-74 (2016) Article DOI: 10.1021/acschembio.5b00640 BindingDB Entry DOI: 10.7270/Q2BZ64T2
					More data for this Ligand-Target Pair
Histone deacetylase 4 (Homo sapiens (Human))	BDBM19149 (CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...) Show SMILES ONC(=O)CCCCCCC(=O)Nc1ccccc1 Show InChI InChI=1S/C14H20N2O3/c17-13(15-12-8-4-3-5-9-12)10-6-1-2-7-11-14(18)16-19/h3-5,8-9,19H,1-2,6-7,10-11H2,(H,15,17)(H,16,18)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	>3.33E+4	n/a	n/a	n/a	n/a	7.4	25
Broad Institute of Harvard and MIT					Assay Description Purified HDAC1-9 (0.5~5 nM) were incubated with 2 μM carboxyfluorescein (FAM)-labeled acetylated peptide substrate A or B and test compound for ...				ACS Chem Biol 11: 363-74 (2016) Article DOI: 10.1021/acschembio.5b00640 BindingDB Entry DOI: 10.7270/Q2BZ64T2
					More data for this Ligand-Target Pair
Histone deacetylase 4 (Homo sapiens (Human))	BDBM19422 (4-(acetylamino)-N-(2-amino-phenyl) benzamide | CI-...) Show SMILES CC(=O)Nc1ccc(cc1)C(=O)Nc1ccccc1N Show InChI InChI=1S/C15H15N3O2/c1-10(19)17-12-8-6-11(7-9-12)15(20)18-14-5-3-2-4-13(14)16/h2-9H,16H2,1H3,(H,17,19)(H,18,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>3.33E+4	n/a	n/a	n/a	n/a	7.4	25
Broad Institute of Harvard and MIT					Assay Description Purified HDAC1-9 (0.5~5 nM) were incubated with 2 μM carboxyfluorescein (FAM)-labeled acetylated peptide substrate A or B and test compound for ...				ACS Chem Biol 11: 363-74 (2016) Article DOI: 10.1021/acschembio.5b00640 BindingDB Entry DOI: 10.7270/Q2BZ64T2
					More data for this Ligand-Target Pair
Histone deacetylase 4 (Homo sapiens (Human))	BDBM178095 (BRD2492) Show SMILES CC(=O)Nc1ccc(cc1)C(=O)Nc1cc(ccc1N)-c1ccncc1 Show InChI InChI=1S/C20H18N4O2/c1-13(25)23-17-5-2-15(3-6-17)20(26)24-19-12-16(4-7-18(19)21)14-8-10-22-11-9-14/h2-12H,21H2,1H3,(H,23,25)(H,24,26)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.33E+4	n/a	n/a	n/a	n/a	7.4	25
Broad Institute of Harvard and MIT					Assay Description Purified HDAC1-9 (0.5~5 nM) were incubated with 2 μM carboxyfluorescein (FAM)-labeled acetylated peptide substrate A or B and test compound for ...				ACS Chem Biol 11: 363-74 (2016) Article DOI: 10.1021/acschembio.5b00640 BindingDB Entry DOI: 10.7270/Q2BZ64T2
					More data for this Ligand-Target Pair
Histone deacetylase 4 (Homo sapiens (Human))	BDBM178100 (BRD3308 | US11377423, Cmpd 1) Show SMILES CC(=O)Nc1ccc(cc1)C(=O)Nc1ccc(F)cc1N Show InChI InChI=1S/C15H14FN3O2/c1-9(20)18-12-5-2-10(3-6-12)15(21)19-14-7-4-11(16)8-13(14)17/h2-8H,17H2,1H3,(H,18,20)(H,19,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.33E+4	n/a	n/a	n/a	n/a	7.4	25
Broad Institute of Harvard and MIT					Assay Description Purified HDAC1-9 (0.5~5 nM) were incubated with 2 μM carboxyfluorescein (FAM)-labeled acetylated peptide substrate A or B and test compound for ...				ACS Chem Biol 11: 363-74 (2016) Article DOI: 10.1021/acschembio.5b00640 BindingDB Entry DOI: 10.7270/Q2BZ64T2
					More data for this Ligand-Target Pair
Histone deacetylase 4 (Homo sapiens (Human))	BDBM49152 (5-chloranyl-7-[(4-ethylpiperazin-1-yl)-pyridin-3-y...) Show SMILES CCN1CCN(CC1)C(c1cccnc1)c1cc(Cl)c2cccnc2c1O Show InChI InChI=1S/C21H23ClN4O/c1-2-25-9-11-26(12-10-25)20(15-5-3-7-23-14-15)17-13-18(22)16-6-4-8-24-19(16)21(17)27/h3-8,13-14,20,27H,2,9-12H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.38E+4	n/a	n/a	n/a	n/a	7.4	n/a
Broad Institute					Assay Description Briefly, this fluorogenic assays uses an acetylated lysine tripeptide substrate, amide-linked to a fluorescently quenched aminocoumarin (AMC). Enzyme...				ACS Chem Biol 11: 1844-51 (2016) Article DOI: 10.1021/acschembio.6b00012 BindingDB Entry DOI: 10.7270/Q2QF8RPQ
					More data for this Ligand-Target Pair
Histone deacetylase 4 (Homo sapiens (Human))	BDBM19410 (CHEMBL27759 | MS-275 | US11377423, MS-275 | US1167...) Show SMILES Nc1ccccc1NC(=O)c1ccc(CNC(=O)OCc2cccnc2)cc1 Show InChI InChI=1S/C21H20N4O3/c22-18-5-1-2-6-19(18)25-20(26)17-9-7-15(8-10-17)13-24-21(27)28-14-16-4-3-11-23-12-16/h1-12H,13-14,22H2,(H,24,27)(H,25,26)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	7.5	n/a
Genentech, Inc.					Assay Description Biochemical assays of HDAC activity were carried out by Nanosyn in a reaction volume of 10 ul in 384-well microplates. A standard enzymatic reaction ...				J Biol Chem 288: 26926-43 (2013) Article DOI: 10.1074/jbc.M113.490706 BindingDB Entry DOI: 10.7270/Q2KK99MZ
					More data for this Ligand-Target Pair
Histone deacetylase 4 (Homo sapiens (Human))	BDBM19423 (HDAC inhibitor, Compound 1 | N-[2-amino-5-(thiophe...) Show SMILES CC(=O)Nc1ccc(cc1)C(=O)Nc1cc(ccc1N)-c1cccs1 Show InChI InChI=1S/C19H17N3O2S/c1-12(23)21-15-7-4-13(5-8-15)19(24)22-17-11-14(6-9-16(17)20)18-3-2-10-25-18/h2-11H,20H2,1H3,(H,21,23)(H,22,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	7.5	n/a
Genentech, Inc.					Assay Description Biochemical assays of HDAC activity were carried out by Nanosyn in a reaction volume of 10 ul in 384-well microplates. A standard enzymatic reaction ...				J Biol Chem 288: 26926-43 (2013) Article DOI: 10.1074/jbc.M113.490706 BindingDB Entry DOI: 10.7270/Q2KK99MZ
					More data for this Ligand-Target Pair
Histone deacetylase 4 (Homo sapiens (Human))	BDBM50276074 (CHEMBL470791 | HDAC inhibitor, Compound 2 | N-(2-a...) Show SMILES Nc1ccc(cc1NC(=O)c1ccc(nc1)N1CCC2(CNC2=O)CC1)-c1cccs1 Show InChI InChI=1S/C23H23N5O2S/c24-17-5-3-15(19-2-1-11-31-19)12-18(17)27-21(29)16-4-6-20(25-13-16)28-9-7-23(8-10-28)14-26-22(23)30/h1-6,11-13H,7-10,14,24H2,(H,26,30)(H,27,29)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	7.5	n/a
Genentech, Inc.					Assay Description Biochemical assays of HDAC activity were carried out by Nanosyn in a reaction volume of 10 ul in 384-well microplates. A standard enzymatic reaction ...				J Biol Chem 288: 26926-43 (2013) Article DOI: 10.1074/jbc.M113.490706 BindingDB Entry DOI: 10.7270/Q2KK99MZ
					More data for this Ligand-Target Pair
Histone deacetylase 4 (Homo sapiens (Human))	BDBM50005711 (CHEBI:46024 | GNF-Pf-1011 | TRICHOSTATIN | Trichos...) Show SMILES C[C@H](\C=C(/C)\C=C\C(=O)NO)C(=O)c1ccc(cc1)N(C)C |r| Show InChI InChI=1S/C17H22N2O3/c1-12(5-10-16(20)18-22)11-13(2)17(21)14-6-8-15(9-7-14)19(3)4/h5-11,13,22H,1-4H3,(H,18,20)/b10-5+,12-11+/t13-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	2.40E+3	n/a	n/a	n/a	n/a	7.5	n/a
Genentech, Inc.					Assay Description Biochemical assays of HDAC activity were carried out by Nanosyn in a reaction volume of 10 ul in 384-well microplates. A standard enzymatic reaction ...				J Biol Chem 288: 26926-43 (2013) Article DOI: 10.1074/jbc.M113.490706 BindingDB Entry DOI: 10.7270/Q2KK99MZ
					More data for this Ligand-Target Pair
Histone deacetylase 4 (Homo sapiens (Human))	BDBM19149 (CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...) Show SMILES ONC(=O)CCCCCCC(=O)Nc1ccccc1 Show InChI InChI=1S/C14H20N2O3/c17-13(15-12-8-4-3-5-9-12)10-6-1-2-7-11-14(18)16-19/h3-5,8-9,19H,1-2,6-7,10-11H2,(H,15,17)(H,16,18)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	7.5	n/a
Genentech, Inc.					Assay Description Biochemical assays of HDAC activity were carried out by Nanosyn in a reaction volume of 10 ul in 384-well microplates. A standard enzymatic reaction ...				J Biol Chem 288: 26926-43 (2013) Article DOI: 10.1074/jbc.M113.490706 BindingDB Entry DOI: 10.7270/Q2KK99MZ
					More data for this Ligand-Target Pair
Histone deacetylase 4 (Homo sapiens (Human))	BDBM19130 ((2E,4E,6R)-7-[4-(dimethylamino)phenyl]-N-hydroxy-4...) Show SMILES CC(C=CC(=O)NO)C=C(C)C(=O)c1ccc(cc1)N(C)C |w:8.7,2.1| Show InChI InChI=1S/C17H22N2O3/c1-12(5-10-16(20)18-22)11-13(2)17(21)14-6-8-15(9-7-14)19(3)4/h5-12,22H,1-4H3,(H,18,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	8.0	37
Kyushu Institute of Technology					Assay Description For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...				Bioorg Med Chem 14: 3438-46 (2006) Article DOI: 10.1016/j.bmc.2005.12.063 BindingDB Entry DOI: 10.7270/Q2P55KRB
					More data for this Ligand-Target Pair
Histone deacetylase 4 (Homo sapiens (Human))	BDBM19156 ((3S,9S,14aR)-9-benzyl-3-(hept-6-en-1-yl)-6,6-dimet...) Show SMILES CC1(C)NC(=O)[C@H](CCCCCC=C)NC(=O)[C@H]2CCCN2C(=O)[C@H](Cc2ccccc2)NC1=O |r| Show InChI InChI=1S/C27H38N4O4/c1-4-5-6-7-11-15-20-23(32)30-27(2,3)26(35)29-21(18-19-13-9-8-10-14-19)25(34)31-17-12-16-22(31)24(33)28-20/h4,8-10,13-14,20-22H,1,5-7,11-12,15-18H2,2-3H3,(H,28,33)(H,29,35)(H,30,32)/t20-,21-,22+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	8.0	37
Kyushu Institute of Technology					Assay Description For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...				Bioorg Med Chem 14: 3438-46 (2006) Article DOI: 10.1016/j.bmc.2005.12.063 BindingDB Entry DOI: 10.7270/Q2P55KRB
					More data for this Ligand-Target Pair
Histone deacetylase 4 (Homo sapiens (Human))	BDBM19157 ((3S,9S,14aR)-9-benzyl-6,6-dimethyl-3-[5-(oxiran-2-...) Show SMILES CC1(C)NC(=O)[C@H](CCCCCC2CO2)NC(=O)[C@H]2CCCN2C(=O)[C@H](Cc2ccccc2)NC1=O |r| Show InChI InChI=1S/C27H38N4O5/c1-27(2)26(35)29-21(16-18-10-5-3-6-11-18)25(34)31-15-9-14-22(31)24(33)28-20(23(32)30-27)13-8-4-7-12-19-17-36-19/h3,5-6,10-11,19-22H,4,7-9,12-17H2,1-2H3,(H,28,33)(H,29,35)(H,30,32)/t19?,20-,21-,22+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.05E+3	n/a	n/a	n/a	n/a	8.0	37
Kyushu Institute of Technology					Assay Description For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...				Bioorg Med Chem 14: 3438-46 (2006) Article DOI: 10.1016/j.bmc.2005.12.063 BindingDB Entry DOI: 10.7270/Q2P55KRB
					More data for this Ligand-Target Pair
Histone deacetylase 4 (Homo sapiens (Human))	BDBM19158 ((3S,9S,14aR)-9-benzyl-3-(7-bromo-6-oxoheptyl)-6,6-...) Show SMILES CC1(C)NC(=O)[C@H](CCCCCC(=O)CBr)NC(=O)[C@H]2CCCN2C(=O)[C@H](Cc2ccccc2)NC1=O |r| Show InChI InChI=1S/C27H37BrN4O5/c1-27(2)26(37)30-21(16-18-10-5-3-6-11-18)25(36)32-15-9-14-22(32)24(35)29-20(23(34)31-27)13-8-4-7-12-19(33)17-28/h3,5-6,10-11,20-22H,4,7-9,12-17H2,1-2H3,(H,29,35)(H,30,37)(H,31,34)/t20-,21-,22+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	59.5	n/a	n/a	n/a	n/a	8.0	37
Kyushu Institute of Technology					Assay Description For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...				Bioorg Med Chem 14: 3438-46 (2006) Article DOI: 10.1016/j.bmc.2005.12.063 BindingDB Entry DOI: 10.7270/Q2P55KRB
					More data for this Ligand-Target Pair
Histone deacetylase 4 (Homo sapiens (Human))	BDBM19159 ((3S,9S,14aR)-9-benzyl-6,6-dimethyl-3-(6-oxoheptyl)...) Show SMILES CC(=O)CCCCC[C@@H]1NC(=O)[C@H]2CCCN2C(=O)[C@H](Cc2ccccc2)NC(=O)C(C)(C)NC1=O |r| Show InChI InChI=1S/C27H38N4O5/c1-18(32)11-6-4-9-14-20-23(33)30-27(2,3)26(36)29-21(17-19-12-7-5-8-13-19)25(35)31-16-10-15-22(31)24(34)28-20/h5,7-8,12-13,20-22H,4,6,9-11,14-17H2,1-3H3,(H,28,34)(H,29,36)(H,30,33)/t20-,21-,22+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	290	n/a	n/a	n/a	n/a	8.0	37
Kyushu Institute of Technology					Assay Description For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...				Bioorg Med Chem 14: 3438-46 (2006) Article DOI: 10.1016/j.bmc.2005.12.063 BindingDB Entry DOI: 10.7270/Q2P55KRB
					More data for this Ligand-Target Pair
Histone deacetylase 4 (Homo sapiens (Human))	BDBM19160 ((3S,9S,14aR)-9-benzyl-3-(6,7-dihydroxyheptyl)-6,6-...) Show SMILES CC1(C)NC(=O)[C@H](CCCCCC(O)CO)NC(=O)[C@H]2CCCN2C(=O)[C@H](Cc2ccccc2)NC1=O |r| Show InChI InChI=1S/C27H40N4O6/c1-27(2)26(37)29-21(16-18-10-5-3-6-11-18)25(36)31-15-9-14-22(31)24(35)28-20(23(34)30-27)13-8-4-7-12-19(33)17-32/h3,5-6,10-11,19-22,32-33H,4,7-9,12-17H2,1-2H3,(H,28,35)(H,29,37)(H,30,34)/t19?,20-,21-,22+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	8.0	37
Kyushu Institute of Technology					Assay Description For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...				Bioorg Med Chem 14: 3438-46 (2006) Article DOI: 10.1016/j.bmc.2005.12.063 BindingDB Entry DOI: 10.7270/Q2P55KRB
					More data for this Ligand-Target Pair
Histone deacetylase 4 (Homo sapiens (Human))	BDBM19161 (6-[(3S,9S,14aR)-9-benzyl-6,6-dimethyl-1,4,7,10-tet...) Show SMILES CC1(C)NC(=O)[C@H](CCCCCC=O)NC(=O)[C@H]2CCCN2C(=O)[C@H](Cc2ccccc2)NC1=O |r| Show InChI InChI=1S/C26H36N4O5/c1-26(2)25(35)28-20(17-18-11-6-5-7-12-18)24(34)30-15-10-14-21(30)23(33)27-19(22(32)29-26)13-8-3-4-9-16-31/h5-7,11-12,16,19-21H,3-4,8-10,13-15,17H2,1-2H3,(H,27,33)(H,28,35)(H,29,32)/t19-,20-,21+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.29E+3	n/a	n/a	n/a	n/a	8.0	37
Kyushu Institute of Technology					Assay Description For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...				Bioorg Med Chem 14: 3438-46 (2006) Article DOI: 10.1016/j.bmc.2005.12.063 BindingDB Entry DOI: 10.7270/Q2P55KRB
					More data for this Ligand-Target Pair
Histone deacetylase 4 (Homo sapiens (Human))	BDBM19162 ((3S,9S,14aR)-9-benzyl-3-(7-hydroxy-6-oxoheptyl)-6,...) Show SMILES CC1(C)NC(=O)[C@H](CCCCCC(=O)CO)NC(=O)[C@H]2CCCN2C(=O)[C@H](Cc2ccccc2)NC1=O |r| Show InChI InChI=1S/C27H38N4O6/c1-27(2)26(37)29-21(16-18-10-5-3-6-11-18)25(36)31-15-9-14-22(31)24(35)28-20(23(34)30-27)13-8-4-7-12-19(33)17-32/h3,5-6,10-11,20-22,32H,4,7-9,12-17H2,1-2H3,(H,28,35)(H,29,37)(H,30,34)/t20-,21-,22+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	60.4	n/a	n/a	n/a	n/a	8.0	37
Kyushu Institute of Technology					Assay Description For the enzyme assay, the enzyme fraction was added to fluorescent substrate in the presence of test compounds, and the mixture was incubated for add...				Bioorg Med Chem 14: 3438-46 (2006) Article DOI: 10.1016/j.bmc.2005.12.063 BindingDB Entry DOI: 10.7270/Q2P55KRB
					More data for this Ligand-Target Pair
Histone deacetylase 4 (Homo sapiens (Human))	BDBM24624 (CHEMBL272980 | MGCD-0103 | MGCD0103 | N-(2-aminoph...) Show SMILES Nc1ccccc1NC(=O)c1ccc(CNc2nccc(n2)-c2cccnc2)cc1 Show InChI InChI=1S/C23H20N6O/c24-19-5-1-2-6-21(19)28-22(30)17-9-7-16(8-10-17)14-27-23-26-13-11-20(29-23)18-4-3-12-25-15-18/h1-13,15H,14,24H2,(H,28,30)(H,26,27,29)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	8.0	37
MethylGene Inc.					Assay Description The HDAC enzyme in vitro assay was based on a homogeneous fluorescence release assay. Purified recombinant HDAC enzymes were incubated with compounds...				J Med Chem 51: 4072-5 (2008) Article DOI: 10.1021/jm800251w BindingDB Entry DOI: 10.7270/Q28P5XTT
					More data for this Ligand-Target Pair
Histone deacetylase 4 (Homo sapiens (Human))	BDBM19149 (CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...) Show SMILES ONC(=O)CCCCCCC(=O)Nc1ccccc1 Show InChI InChI=1S/C14H20N2O3/c17-13(15-12-8-4-3-5-9-12)10-6-1-2-7-11-14(18)16-19/h3-5,8-9,19H,1-2,6-7,10-11H2,(H,15,17)(H,16,18)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	8.0	37
IRBM/Merck					Assay Description The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...				J Med Chem 51: 2350-3 (2008) Article DOI: 10.1021/jm800079s BindingDB Entry DOI: 10.7270/Q2W957H9
					More data for this Ligand-Target Pair
Histone deacetylase 4 (Homo sapiens (Human))	BDBM19410 (CHEMBL27759 | MS-275 | US11377423, MS-275 | US1167...) Show SMILES Nc1ccccc1NC(=O)c1ccc(CNC(=O)OCc2cccnc2)cc1 Show InChI InChI=1S/C21H20N4O3/c22-18-5-1-2-6-19(18)25-20(26)17-9-7-15(8-10-17)13-24-21(27)28-14-16-4-3-11-23-12-16/h1-12H,13-14,22H2,(H,24,27)(H,25,26)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	8.0	37
IRBM/Merck					Assay Description The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...				J Med Chem 51: 2350-3 (2008) Article DOI: 10.1021/jm800079s BindingDB Entry DOI: 10.7270/Q2W957H9
					More data for this Ligand-Target Pair
Histone deacetylase 4 (Homo sapiens (Human))	BDBM25146 (2-(5-methoxy-2-methyl-1H-indol-3-yl)-N-[(1S)-7-oxo...) Show SMILES COc1ccc2[nH]c(C)c(CC(=O)N[C@@H](CCCCCC(C)=O)c3nc(c[nH]3)-c3ccccc3)c2c1 |r| Show InChI InChI=1S/C29H34N4O3/c1-19(34)10-6-4-9-13-26(29-30-18-27(33-29)21-11-7-5-8-12-21)32-28(35)17-23-20(2)31-25-15-14-22(36-3)16-24(23)25/h5,7-8,11-12,14-16,18,26,31H,4,6,9-10,13,17H2,1-3H3,(H,30,33)(H,32,35)/t26-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	8.0	37
IRBM/Merck					Assay Description The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...				J Med Chem 51: 2350-3 (2008) Article DOI: 10.1021/jm800079s BindingDB Entry DOI: 10.7270/Q2W957H9
					More data for this Ligand-Target Pair
Histone deacetylase 4 (Homo sapiens (Human))	BDBM25147 (N-[(1S)-1-(6-chloro-1H-1,3-benzodiazol-2-yl)-7-oxo...) Show SMILES COc1ccc2[nH]c(C)c(CC(=O)N[C@@H](CCCCCC(C)=O)c3nc4ccc(Cl)cc4[nH]3)c2c1 |r| Show InChI InChI=1S/C27H31ClN4O3/c1-16(33)7-5-4-6-8-24(27-31-23-11-9-18(28)13-25(23)32-27)30-26(34)15-20-17(2)29-22-12-10-19(35-3)14-21(20)22/h9-14,24,29H,4-8,15H2,1-3H3,(H,30,34)(H,31,32)/t24-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	8.0	37
IRBM/Merck					Assay Description The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...				J Med Chem 51: 2350-3 (2008) Article DOI: 10.1021/jm800079s BindingDB Entry DOI: 10.7270/Q2W957H9
					More data for this Ligand-Target Pair
Histone deacetylase 4 (Homo sapiens (Human))	BDBM25148 (2-(5-methoxy-2-methyl-1H-indol-3-yl)-N-[(1S)-7-oxo...) Show SMILES CCC(=O)CCCCC[C@H](NC(=O)Cc1c(C)[nH]c2ccc(OC)cc12)c1nc(c[nH]1)-c1ccccc1 |r| Show InChI InChI=1S/C30H36N4O3/c1-4-22(35)13-9-6-10-14-27(30-31-19-28(34-30)21-11-7-5-8-12-21)33-29(36)18-24-20(2)32-26-16-15-23(37-3)17-25(24)26/h5,7-8,11-12,15-17,19,27,32H,4,6,9-10,13-14,18H2,1-3H3,(H,31,34)(H,33,36)/t27-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	8.0	37
IRBM/Merck					Assay Description The Fluor-de-Lys HDAC activity assay kit (Biomol) was used. Purified recombinant HDAC enzyme was incubated with Fluor-de-Lys substrate in the presenc...				J Med Chem 51: 2350-3 (2008) Article DOI: 10.1021/jm800079s BindingDB Entry DOI: 10.7270/Q2W957H9
					More data for this Ligand-Target Pair
Histone deacetylase 4 (Homo sapiens (Human))	BDBM50380399 (CHEMBL2018302 | Tubastatin A | US10227295, Compoun...) Show SMILES CN1CCc2c(C1)c1ccccc1n2Cc1ccc(cc1)C(=O)NO Show InChI InChI=1S/C20H21N3O2/c1-22-11-10-19-17(13-22)16-4-2-3-5-18(16)23(19)12-14-6-8-15(9-7-14)20(24)21-25/h2-9,25H,10-13H2,1H3,(H,21,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	US Patent	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	8.0	25
The Board of Trustees of The University of Illinois US Patent					Assay Description HDAC assay is performed using fluorescently-labeled acetylated substrate, which comprises an acetylated lysine side chain. After incubation with HDAC...				US Patent US8748451 (2014) BindingDB Entry DOI: 10.7270/Q26D5RPK
					More data for this Ligand-Target Pair
Histone deacetylase 4 (Homo sapiens (Human))	BDBM163619 (UF010 | US10807944, Compound UF010 | US11731934, C...) Show SMILES CCCCNNC(=O)c1ccc(Br)cc1 Show InChI InChI=1S/C11H15BrN2O/c1-2-3-8-13-14-11(15)9-4-6-10(12)7-5-9/h4-7,13H,2-3,8H2,1H3,(H,14,15)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	8.0	n/a
University of Florida College of Medicine; Northwest Agriculture and Forestry University					Assay Description Activity against HDACs 1 to 11 was assessed by using an acetylated 7-amino-4-methylcoumarin (AMC)-labeled peptide substrate. A substrate based on res...				Chem Biol 22: 273-84 (2015) Article DOI: 10.1016/j.chembiol.2014.12.015 BindingDB Entry DOI: 10.7270/Q2TX3D48
					More data for this Ligand-Target Pair
Histone deacetylase 4 (Homo sapiens (Human))	BDBM162728 (US9056843, 19) Show SMILES FC(F)(F)c1nc(no1)-c1ccc(cc1)C(=O)NC1CC1 Show InChI InChI=1S/C13H10F3N3O2/c14-13(15,16)12-18-10(19-21-12)7-1-3-8(4-2-7)11(20)17-9-5-6-9/h1-4,9H,5-6H2,(H,17,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	US Patent	n/a	n/a	120	n/a	n/a	n/a	n/a	8.0	25
NOVARTIS AG US Patent					Assay Description Human recombinant HDAC4 was expressed in full length form (aa 2-1084) in Sf9 insect cells (obtained from ATCC) using baculovirus generated with Bac-t...				US Patent US9056843 (2015) BindingDB Entry DOI: 10.7270/Q24F1PG8
					More data for this Ligand-Target Pair
Histone deacetylase 4 (Homo sapiens (Human))	BDBM162750 (US9056843, 41) Show SMILES CN(C)c1ccc(NC(=O)c2ccc(cc2)-c2noc(n2)C(F)(F)F)cc1 Show InChI InChI=1S/C18H15F3N4O2/c1-25(2)14-9-7-13(8-10-14)22-16(26)12-5-3-11(4-6-12)15-23-17(27-24-15)18(19,20)21/h3-10H,1-2H3,(H,22,26)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	8.0	25
NOVARTIS AG US Patent					Assay Description Human recombinant HDAC4 was expressed in full length form (aa 2-1084) in Sf9 insect cells (obtained from ATCC) using baculovirus generated with Bac-t...				US Patent US9056843 (2015) BindingDB Entry DOI: 10.7270/Q24F1PG8
					More data for this Ligand-Target Pair
Histone deacetylase 4 (Homo sapiens (Human))	BDBM162779 (US9056843, 70) Show SMILES Cc1cc(NC(=O)c2ccc(cc2)-c2noc(n2)C(F)(F)F)ccn1 Show InChI InChI=1S/C16H11F3N4O2/c1-9-8-12(6-7-20-9)21-14(24)11-4-2-10(3-5-11)13-22-15(25-23-13)16(17,18)19/h2-8H,1H3,(H,20,21,24)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	90	n/a	n/a	n/a	n/a	8.0	25
NOVARTIS AG US Patent					Assay Description Human recombinant HDAC4 was expressed in full length form (aa 2-1084) in Sf9 insect cells (obtained from ATCC) using baculovirus generated with Bac-t...				US Patent US9056843 (2015) BindingDB Entry DOI: 10.7270/Q24F1PG8
					More data for this Ligand-Target Pair
Histone deacetylase 4 (Homo sapiens (Human))	BDBM162809 (US9056843, 100) Show SMILES FC(F)(F)c1nc(no1)-c1ccc(cc1)S(=O)(=O)Nc1cccnc1 Show InChI InChI=1S/C14H9F3N4O3S/c15-14(16,17)13-19-12(20-24-13)9-3-5-11(6-4-9)25(22,23)21-10-2-1-7-18-8-10/h1-8,21H	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	70	n/a	n/a	n/a	n/a	8.0	25
NOVARTIS AG US Patent					Assay Description Human recombinant HDAC4 was expressed in full length form (aa 2-1084) in Sf9 insect cells (obtained from ATCC) using baculovirus generated with Bac-t...				US Patent US9056843 (2015) BindingDB Entry DOI: 10.7270/Q24F1PG8
					More data for this Ligand-Target Pair
Histone deacetylase 4 (Homo sapiens (Human))	BDBM162815 (US9056843, 106) Show SMILES Fc1cccc(NS(=O)(=O)c2ccc(cc2)-c2noc(n2)C(F)(F)F)c1 Show InChI InChI=1S/C15H9F4N3O3S/c16-10-2-1-3-11(8-10)22-26(23,24)12-6-4-9(5-7-12)13-20-14(25-21-13)15(17,18)19/h1-8,22H	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	US Patent	n/a	n/a	200	n/a	n/a	n/a	n/a	8.0	25
NOVARTIS AG US Patent					Assay Description Human recombinant HDAC4 was expressed in full length form (aa 2-1084) in Sf9 insect cells (obtained from ATCC) using baculovirus generated with Bac-t...				US Patent US9056843 (2015) BindingDB Entry DOI: 10.7270/Q24F1PG8
					More data for this Ligand-Target Pair
Histone deacetylase 4 (Homo sapiens (Human))	BDBM162842 (US9056843, 133) Show SMILES CCN(CC)C[C@H](C)NC(=O)c1ccc(cc1)-c1noc(n1)C(F)(F)F |r| Show InChI InChI=1S/C17H21F3N4O2/c1-4-24(5-2)10-11(3)21-15(25)13-8-6-12(7-9-13)14-22-16(26-23-14)17(18,19)20/h6-9,11H,4-5,10H2,1-3H3,(H,21,25)/t11-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	48	n/a	n/a	n/a	n/a	8.0	25
NOVARTIS AG US Patent					Assay Description Human recombinant HDAC4 was expressed in full length form (aa 2-1084) in Sf9 insect cells (obtained from ATCC) using baculovirus generated with Bac-t...				US Patent US9056843 (2015) BindingDB Entry DOI: 10.7270/Q24F1PG8
					More data for this Ligand-Target Pair
Histone deacetylase 4 (Homo sapiens (Human))	BDBM162849 (US9056843, 140) Show SMILES CCN(C)C[C@@H](C)NC(=O)c1ccc(cc1F)-c1noc(n1)C(F)(F)F |r| Show InChI InChI=1S/C16H18F4N4O2/c1-4-24(3)8-9(2)21-14(25)11-6-5-10(7-12(11)17)13-22-15(26-23-13)16(18,19)20/h5-7,9H,4,8H2,1-3H3,(H,21,25)/t9-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	72	n/a	n/a	n/a	n/a	8.0	25
NOVARTIS AG US Patent					Assay Description Human recombinant HDAC4 was expressed in full length form (aa 2-1084) in Sf9 insect cells (obtained from ATCC) using baculovirus generated with Bac-t...				US Patent US9056843 (2015) BindingDB Entry DOI: 10.7270/Q24F1PG8
					More data for this Ligand-Target Pair
Histone deacetylase 4 (Homo sapiens (Human))	BDBM162710 (US9056843, 1) Show SMILES CN(C)C(=O)c1ccc(cc1)-c1noc(n1)C(F)(F)F Show InChI InChI=1S/C12H10F3N3O2/c1-18(2)10(19)8-5-3-7(4-6-8)9-16-11(20-17-9)12(13,14)15/h3-6H,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	360	n/a	n/a	n/a	n/a	8.0	25
NOVARTIS AG US Patent					Assay Description Human recombinant HDAC4 was expressed in full length form (aa 2-1084) in Sf9 insect cells (obtained from ATCC) using baculovirus generated with Bac-t...				US Patent US9056843 (2015) BindingDB Entry DOI: 10.7270/Q24F1PG8
					More data for this Ligand-Target Pair
Histone deacetylase 4 (Homo sapiens (Human))	BDBM162711 (US9056843, 2) Show SMILES CNC(=O)c1ccc(cc1)-c1noc(n1)C(F)(F)F Show InChI InChI=1S/C11H8F3N3O2/c1-15-9(18)7-4-2-6(3-5-7)8-16-10(19-17-8)11(12,13)14/h2-5H,1H3,(H,15,18)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	US Patent	n/a	n/a	530	n/a	n/a	n/a	n/a	8.0	25
NOVARTIS AG US Patent					Assay Description Human recombinant HDAC4 was expressed in full length form (aa 2-1084) in Sf9 insect cells (obtained from ATCC) using baculovirus generated with Bac-t...				US Patent US9056843 (2015) BindingDB Entry DOI: 10.7270/Q24F1PG8
					More data for this Ligand-Target Pair
Histone deacetylase 4 (Homo sapiens (Human))	BDBM162712 (US9056843, 3) Show SMILES CNC(=O)Cc1ccc(cc1)-c1noc(n1)C(F)(F)F Show InChI InChI=1S/C12H10F3N3O2/c1-16-9(19)6-7-2-4-8(5-3-7)10-17-11(20-18-10)12(13,14)15/h2-5H,6H2,1H3,(H,16,19)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	8.0	25
NOVARTIS AG US Patent					Assay Description Human recombinant HDAC4 was expressed in full length form (aa 2-1084) in Sf9 insect cells (obtained from ATCC) using baculovirus generated with Bac-t...				US Patent US9056843 (2015) BindingDB Entry DOI: 10.7270/Q24F1PG8
					More data for this Ligand-Target Pair
Histone deacetylase 4 (Homo sapiens (Human))	BDBM162713 (US9056843, 4) Show SMILES CN(C)C(=O)Cc1ccc(cc1)-c1noc(n1)C(F)(F)F Show InChI InChI=1S/C13H12F3N3O2/c1-19(2)10(20)7-8-3-5-9(6-4-8)11-17-12(21-18-11)13(14,15)16/h3-6H,7H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	620	n/a	n/a	n/a	n/a	8.0	25
NOVARTIS AG US Patent					Assay Description Human recombinant HDAC4 was expressed in full length form (aa 2-1084) in Sf9 insect cells (obtained from ATCC) using baculovirus generated with Bac-t...				US Patent US9056843 (2015) BindingDB Entry DOI: 10.7270/Q24F1PG8
					More data for this Ligand-Target Pair
Histone deacetylase 4 (Homo sapiens (Human))	BDBM162714 (US9056843, 5) Show SMILES CC(C)NC(=O)Cc1ccc(cc1)-c1noc(n1)C(F)(F)F Show InChI InChI=1S/C14H14F3N3O2/c1-8(2)18-11(21)7-9-3-5-10(6-4-9)12-19-13(22-20-12)14(15,16)17/h3-6,8H,7H2,1-2H3,(H,18,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	970	n/a	n/a	n/a	n/a	8.0	25
NOVARTIS AG US Patent					Assay Description Human recombinant HDAC4 was expressed in full length form (aa 2-1084) in Sf9 insect cells (obtained from ATCC) using baculovirus generated with Bac-t...				US Patent US9056843 (2015) BindingDB Entry DOI: 10.7270/Q24F1PG8
					More data for this Ligand-Target Pair
Histone deacetylase 4 (Homo sapiens (Human))	BDBM162715 (US9056843, 6) Show SMILES CCCCNC(=O)Cc1ccc(cc1)-c1noc(n1)C(F)(F)F Show InChI InChI=1S/C15H16F3N3O2/c1-2-3-8-19-12(22)9-10-4-6-11(7-5-10)13-20-14(23-21-13)15(16,17)18/h4-7H,2-3,8-9H2,1H3,(H,19,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	630	n/a	n/a	n/a	n/a	8.0	25
NOVARTIS AG US Patent					Assay Description Human recombinant HDAC4 was expressed in full length form (aa 2-1084) in Sf9 insect cells (obtained from ATCC) using baculovirus generated with Bac-t...				US Patent US9056843 (2015) BindingDB Entry DOI: 10.7270/Q24F1PG8
					More data for this Ligand-Target Pair
Histone deacetylase 4 (Homo sapiens (Human))	BDBM162716 (US9056843, 7) Show SMILES COCCNC(=O)Cc1ccc(cc1)-c1noc(n1)C(F)(F)F Show InChI InChI=1S/C14H14F3N3O3/c1-22-7-6-18-11(21)8-9-2-4-10(5-3-9)12-19-13(23-20-12)14(15,16)17/h2-5H,6-8H2,1H3,(H,18,21)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	960	n/a	n/a	n/a	n/a	8.0	25
NOVARTIS AG US Patent					Assay Description Human recombinant HDAC4 was expressed in full length form (aa 2-1084) in Sf9 insect cells (obtained from ATCC) using baculovirus generated with Bac-t...				US Patent US9056843 (2015) BindingDB Entry DOI: 10.7270/Q24F1PG8
					More data for this Ligand-Target Pair
Histone deacetylase 4 (Homo sapiens (Human))	BDBM162717 (US9056843, 8) Show SMILES CCOC(=O)CNC(=O)Cc1ccc(cc1)-c1noc(n1)C(F)(F)F Show InChI InChI=1S/C15H14F3N3O4/c1-2-24-12(23)8-19-11(22)7-9-3-5-10(6-4-9)13-20-14(25-21-13)15(16,17)18/h3-6H,2,7-8H2,1H3,(H,19,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	580	n/a	n/a	n/a	n/a	8.0	25
NOVARTIS AG US Patent					Assay Description Human recombinant HDAC4 was expressed in full length form (aa 2-1084) in Sf9 insect cells (obtained from ATCC) using baculovirus generated with Bac-t...				US Patent US9056843 (2015) BindingDB Entry DOI: 10.7270/Q24F1PG8
					More data for this Ligand-Target Pair
Histone deacetylase 4 (Homo sapiens (Human))	BDBM162718 (US9056843, 9) Show SMILES FC(F)(F)c1nc(no1)-c1ccc(CC(=O)N2CCOCC2)cc1 Show InChI InChI=1S/C15H14F3N3O3/c16-15(17,18)14-19-13(20-24-14)11-3-1-10(2-4-11)9-12(22)21-5-7-23-8-6-21/h1-4H,5-9H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	850	n/a	n/a	n/a	n/a	8.0	25
NOVARTIS AG US Patent					Assay Description Human recombinant HDAC4 was expressed in full length form (aa 2-1084) in Sf9 insect cells (obtained from ATCC) using baculovirus generated with Bac-t...				US Patent US9056843 (2015) BindingDB Entry DOI: 10.7270/Q24F1PG8
					More data for this Ligand-Target Pair
Histone deacetylase 4 (Homo sapiens (Human))	BDBM162719 (US9056843, 10) Show SMILES CN1CCN(CC1)C(=O)Cc1ccc(cc1)-c1noc(n1)C(F)(F)F Show InChI InChI=1S/C16H17F3N4O2/c1-22-6-8-23(9-7-22)13(24)10-11-2-4-12(5-3-11)14-20-15(25-21-14)16(17,18)19/h2-5H,6-10H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	8.0	25
NOVARTIS AG US Patent					Assay Description Human recombinant HDAC4 was expressed in full length form (aa 2-1084) in Sf9 insect cells (obtained from ATCC) using baculovirus generated with Bac-t...				US Patent US9056843 (2015) BindingDB Entry DOI: 10.7270/Q24F1PG8
					More data for this Ligand-Target Pair
Histone deacetylase 4 (Homo sapiens (Human))	BDBM162720 (US9056843, 11) Show SMILES CON(C)C(=O)Cc1ccc(cc1)-c1noc(n1)C(F)(F)F Show InChI InChI=1S/C13H12F3N3O3/c1-19(21-2)10(20)7-8-3-5-9(6-4-8)11-17-12(22-18-11)13(14,15)16/h3-6H,7H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	8.0	25
NOVARTIS AG US Patent					Assay Description Human recombinant HDAC4 was expressed in full length form (aa 2-1084) in Sf9 insect cells (obtained from ATCC) using baculovirus generated with Bac-t...				US Patent US9056843 (2015) BindingDB Entry DOI: 10.7270/Q24F1PG8
					More data for this Ligand-Target Pair
Histone deacetylase 4 (Homo sapiens (Human))	BDBM162721 (US9056843, 12) Show SMILES CCNC(=O)c1ccc(cc1)-c1noc(n1)C(F)(F)F Show InChI InChI=1S/C12H10F3N3O2/c1-2-16-10(19)8-5-3-7(4-6-8)9-17-11(20-18-9)12(13,14)15/h3-6H,2H2,1H3,(H,16,19)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	430	n/a	n/a	n/a	n/a	8.0	25
NOVARTIS AG US Patent					Assay Description Human recombinant HDAC4 was expressed in full length form (aa 2-1084) in Sf9 insect cells (obtained from ATCC) using baculovirus generated with Bac-t...				US Patent US9056843 (2015) BindingDB Entry DOI: 10.7270/Q24F1PG8
					More data for this Ligand-Target Pair
Histone deacetylase 4 (Homo sapiens (Human))	BDBM162722 (US9056843, 13 | US9056843, 17) Show SMILES OCCNC(=O)c1ccc(cc1)-c1noc(n1)C(F)(F)F Show InChI InChI=1S/C12H10F3N3O3/c13-12(14,15)11-17-9(18-21-11)7-1-3-8(4-2-7)10(20)16-5-6-19/h1-4,19H,5-6H2,(H,16,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	US Patent	n/a	n/a	660	n/a	n/a	n/a	n/a	8.0	25
NOVARTIS AG US Patent					Assay Description Human recombinant HDAC4 was expressed in full length form (aa 2-1084) in Sf9 insect cells (obtained from ATCC) using baculovirus generated with Bac-t...				US Patent US9056843 (2015) BindingDB Entry DOI: 10.7270/Q24F1PG8
					More data for this Ligand-Target Pair
Histone deacetylase 4 (Homo sapiens (Human))	BDBM162723 (US9056843, 14) Show SMILES CCN(C)C(=O)c1ccc(cc1)-c1noc(n1)C(F)(F)F Show InChI InChI=1S/C13H12F3N3O2/c1-3-19(2)11(20)9-6-4-8(5-7-9)10-17-12(21-18-10)13(14,15)16/h4-7H,3H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	US Patent	n/a	n/a	900	n/a	n/a	n/a	n/a	8.0	25
NOVARTIS AG US Patent					Assay Description Human recombinant HDAC4 was expressed in full length form (aa 2-1084) in Sf9 insect cells (obtained from ATCC) using baculovirus generated with Bac-t...				US Patent US9056843 (2015) BindingDB Entry DOI: 10.7270/Q24F1PG8
					More data for this Ligand-Target Pair

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