Affinity Data by Patent

Patent code US8853226

Found 26 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM135818 (US10085990, Example 92 \| US10568888, Example 92 \| ...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	68	n/a	n/a	n/a	n/a	n/a	n/a
High Point Pharmaceuticals, LLC US Patent					Assay Description A TR-FRET-based phosphodiesterase assay kit from "Molecular Devices" was used to test whether these compounds were indeed direct inhibitors of the PD...				US Patent US8853226 (2014) BindingDB Entry DOI: 10.7270/Q28C9TZS
High Point Pharmaceuticals, LLC US Patent					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Homo sapiens (Human))	BDBM135818 (US10085990, Example 92 \| US10568888, Example 92 \| ...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	151	n/a	n/a	n/a	n/a	n/a	n/a
High Point Pharmaceuticals, LLC US Patent					Assay Description A TR-FRET-based phosphodiesterase assay kit from "Molecular Devices" was used to test whether these compounds were indeed direct inhibitors of the PD...				US Patent US8853226 (2014) BindingDB Entry DOI: 10.7270/Q28C9TZS
High Point Pharmaceuticals, LLC US Patent					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM135812 (US10085990, Example 30 \| US10568888, Example 30 \| ...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
High Point Pharmaceuticals, LLC US Patent					Assay Description A TR-FRET-based phosphodiesterase assay kit from "Molecular Devices" was used to test whether these compounds were indeed direct inhibitors of the PD...				US Patent US8853226 (2014) BindingDB Entry DOI: 10.7270/Q28C9TZS
High Point Pharmaceuticals, LLC US Patent					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM135821 (US10085990, Example 118 \| US10568888, Example 118 ...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
High Point Pharmaceuticals, LLC US Patent					Assay Description A TR-FRET-based phosphodiesterase assay kit from "Molecular Devices" was used to test whether these compounds were indeed direct inhibitors of the PD...				US Patent US8853226 (2014) BindingDB Entry DOI: 10.7270/Q28C9TZS
High Point Pharmaceuticals, LLC US Patent					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM135822 (US10085990, Example 121 \| US10568888, Example 121 ...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
High Point Pharmaceuticals, LLC US Patent					Assay Description A TR-FRET-based phosphodiesterase assay kit from "Molecular Devices" was used to test whether these compounds were indeed direct inhibitors of the PD...				US Patent US8853226 (2014) BindingDB Entry DOI: 10.7270/Q28C9TZS
High Point Pharmaceuticals, LLC US Patent					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Homo sapiens (Human))	BDBM135812 (US10085990, Example 30 \| US10568888, Example 30 \| ...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
High Point Pharmaceuticals, LLC US Patent					Assay Description A TR-FRET-based phosphodiesterase assay kit from "Molecular Devices" was used to test whether these compounds were indeed direct inhibitors of the PD...				US Patent US8853226 (2014) BindingDB Entry DOI: 10.7270/Q28C9TZS
High Point Pharmaceuticals, LLC US Patent					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Homo sapiens (Human))	BDBM135824 (US10085990, Example 127 \| US10568888, Example 127 ...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	73	n/a	n/a	n/a	n/a	n/a	n/a
High Point Pharmaceuticals, LLC US Patent					Assay Description A TR-FRET-based phosphodiesterase assay kit from "Molecular Devices" was used to test whether these compounds were indeed direct inhibitors of the PD...				US Patent US8853226 (2014) BindingDB Entry DOI: 10.7270/Q28C9TZS
High Point Pharmaceuticals, LLC US Patent					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM135815 (US10085990, Example 51 \| US10568888, Example 51 \| ...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	126	n/a	n/a	n/a	n/a	n/a	n/a
High Point Pharmaceuticals, LLC US Patent					Assay Description A TR-FRET-based phosphodiesterase assay kit from "Molecular Devices" was used to test whether these compounds were indeed direct inhibitors of the PD...				US Patent US8853226 (2014) BindingDB Entry DOI: 10.7270/Q28C9TZS
High Point Pharmaceuticals, LLC US Patent					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Homo sapiens (Human))	BDBM135814 (US10085990, Example 33 \| US10568888, Example 33 \| ...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
High Point Pharmaceuticals, LLC US Patent					Assay Description A TR-FRET-based phosphodiesterase assay kit from "Molecular Devices" was used to test whether these compounds were indeed direct inhibitors of the PD...				US Patent US8853226 (2014) BindingDB Entry DOI: 10.7270/Q28C9TZS
High Point Pharmaceuticals, LLC US Patent					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Homo sapiens (Human))	BDBM135820 (US10085990, Example 115 \| US10568888, Example 115 ...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	163	n/a	n/a	n/a	n/a	n/a	n/a
High Point Pharmaceuticals, LLC US Patent					Assay Description A TR-FRET-based phosphodiesterase assay kit from "Molecular Devices" was used to test whether these compounds were indeed direct inhibitors of the PD...				US Patent US8853226 (2014) BindingDB Entry DOI: 10.7270/Q28C9TZS
High Point Pharmaceuticals, LLC US Patent					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM135824 (US10085990, Example 127 \| US10568888, Example 127 ...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
High Point Pharmaceuticals, LLC US Patent					Assay Description A TR-FRET-based phosphodiesterase assay kit from "Molecular Devices" was used to test whether these compounds were indeed direct inhibitors of the PD...				US Patent US8853226 (2014) BindingDB Entry DOI: 10.7270/Q28C9TZS
High Point Pharmaceuticals, LLC US Patent					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM135817 (US10085990, Example 84 \| US10568888, Example 84 \| ...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	513	n/a	n/a	n/a	n/a	n/a	n/a
High Point Pharmaceuticals, LLC US Patent					Assay Description A TR-FRET-based phosphodiesterase assay kit from "Molecular Devices" was used to test whether these compounds were indeed direct inhibitors of the PD...				US Patent US8853226 (2014) BindingDB Entry DOI: 10.7270/Q28C9TZS
High Point Pharmaceuticals, LLC US Patent					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM135819 (US10085990, Example 103 \| US10568888, Example 103 ...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
High Point Pharmaceuticals, LLC US Patent					Assay Description A TR-FRET-based phosphodiesterase assay kit from "Molecular Devices" was used to test whether these compounds were indeed direct inhibitors of the PD...				US Patent US8853226 (2014) BindingDB Entry DOI: 10.7270/Q28C9TZS
High Point Pharmaceuticals, LLC US Patent					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Homo sapiens (Human))	BDBM135813 (US10085990, Example 32 \| US10568888, Example 32 \| ...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
High Point Pharmaceuticals, LLC US Patent					Assay Description A TR-FRET-based phosphodiesterase assay kit from "Molecular Devices" was used to test whether these compounds were indeed direct inhibitors of the PD...				US Patent US8853226 (2014) BindingDB Entry DOI: 10.7270/Q28C9TZS
High Point Pharmaceuticals, LLC US Patent					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Homo sapiens (Human))	BDBM135815 (US10085990, Example 51 \| US10568888, Example 51 \| ...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	616	n/a	n/a	n/a	n/a	n/a	n/a
High Point Pharmaceuticals, LLC US Patent					Assay Description A TR-FRET-based phosphodiesterase assay kit from "Molecular Devices" was used to test whether these compounds were indeed direct inhibitors of the PD...				US Patent US8853226 (2014) BindingDB Entry DOI: 10.7270/Q28C9TZS
High Point Pharmaceuticals, LLC US Patent					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Homo sapiens (Human))	BDBM135816 (US10085990, Example 54 \| US10568888, Example 54 \| ...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	338	n/a	n/a	n/a	n/a	n/a	n/a
High Point Pharmaceuticals, LLC US Patent					Assay Description A TR-FRET-based phosphodiesterase assay kit from "Molecular Devices" was used to test whether these compounds were indeed direct inhibitors of the PD...				US Patent US8853226 (2014) BindingDB Entry DOI: 10.7270/Q28C9TZS
High Point Pharmaceuticals, LLC US Patent					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Homo sapiens (Human))	BDBM135823 (US10085990, Example 122 \| US10568888, Example 122 ...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
High Point Pharmaceuticals, LLC US Patent					Assay Description A TR-FRET-based phosphodiesterase assay kit from "Molecular Devices" was used to test whether these compounds were indeed direct inhibitors of the PD...				US Patent US8853226 (2014) BindingDB Entry DOI: 10.7270/Q28C9TZS
High Point Pharmaceuticals, LLC US Patent					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM135820 (US10085990, Example 115 \| US10568888, Example 115 ...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	49	n/a	n/a	n/a	n/a	n/a	n/a
High Point Pharmaceuticals, LLC US Patent					Assay Description A TR-FRET-based phosphodiesterase assay kit from "Molecular Devices" was used to test whether these compounds were indeed direct inhibitors of the PD...				US Patent US8853226 (2014) BindingDB Entry DOI: 10.7270/Q28C9TZS
High Point Pharmaceuticals, LLC US Patent					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Homo sapiens (Human))	BDBM135821 (US10085990, Example 118 \| US10568888, Example 118 ...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	206	n/a	n/a	n/a	n/a	n/a	n/a
High Point Pharmaceuticals, LLC US Patent					Assay Description A TR-FRET-based phosphodiesterase assay kit from "Molecular Devices" was used to test whether these compounds were indeed direct inhibitors of the PD...				US Patent US8853226 (2014) BindingDB Entry DOI: 10.7270/Q28C9TZS
High Point Pharmaceuticals, LLC US Patent					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Homo sapiens (Human))	BDBM135822 (US10085990, Example 121 \| US10568888, Example 121 ...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	59	n/a	n/a	n/a	n/a	n/a	n/a
High Point Pharmaceuticals, LLC US Patent					Assay Description A TR-FRET-based phosphodiesterase assay kit from "Molecular Devices" was used to test whether these compounds were indeed direct inhibitors of the PD...				US Patent US8853226 (2014) BindingDB Entry DOI: 10.7270/Q28C9TZS
High Point Pharmaceuticals, LLC US Patent					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM135816 (US10085990, Example 54 \| US10568888, Example 54 \| ...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	78	n/a	n/a	n/a	n/a	n/a	n/a
High Point Pharmaceuticals, LLC US Patent					Assay Description A TR-FRET-based phosphodiesterase assay kit from "Molecular Devices" was used to test whether these compounds were indeed direct inhibitors of the PD...				US Patent US8853226 (2014) BindingDB Entry DOI: 10.7270/Q28C9TZS
High Point Pharmaceuticals, LLC US Patent					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Homo sapiens (Human))	BDBM135817 (US10085990, Example 84 \| US10568888, Example 84 \| ...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	827	n/a	n/a	n/a	n/a	n/a	n/a
High Point Pharmaceuticals, LLC US Patent					Assay Description A TR-FRET-based phosphodiesterase assay kit from "Molecular Devices" was used to test whether these compounds were indeed direct inhibitors of the PD...				US Patent US8853226 (2014) BindingDB Entry DOI: 10.7270/Q28C9TZS
High Point Pharmaceuticals, LLC US Patent					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4D (Homo sapiens (Human))	BDBM135819 (US10085990, Example 103 \| US10568888, Example 103 ...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
High Point Pharmaceuticals, LLC US Patent					Assay Description A TR-FRET-based phosphodiesterase assay kit from "Molecular Devices" was used to test whether these compounds were indeed direct inhibitors of the PD...				US Patent US8853226 (2014) BindingDB Entry DOI: 10.7270/Q28C9TZS
High Point Pharmaceuticals, LLC US Patent					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM135813 (US10085990, Example 32 \| US10568888, Example 32 \| ...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
High Point Pharmaceuticals, LLC US Patent					Assay Description A TR-FRET-based phosphodiesterase assay kit from "Molecular Devices" was used to test whether these compounds were indeed direct inhibitors of the PD...				US Patent US8853226 (2014) BindingDB Entry DOI: 10.7270/Q28C9TZS
High Point Pharmaceuticals, LLC US Patent					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM135814 (US10085990, Example 33 \| US10568888, Example 33 \| ...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.24E+4	n/a	n/a	n/a	n/a	n/a	n/a
High Point Pharmaceuticals, LLC US Patent					Assay Description A TR-FRET-based phosphodiesterase assay kit from "Molecular Devices" was used to test whether these compounds were indeed direct inhibitors of the PD...				US Patent US8853226 (2014) BindingDB Entry DOI: 10.7270/Q28C9TZS
High Point Pharmaceuticals, LLC US Patent					More data for this Ligand-Target Pair
cAMP-specific 3',5'-cyclic phosphodiesterase 4B (Homo sapiens (Human))	BDBM135823 (US10085990, Example 122 \| US10568888, Example 122 ...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	39	n/a	n/a	n/a	n/a	n/a	n/a
High Point Pharmaceuticals, LLC US Patent					Assay Description A TR-FRET-based phosphodiesterase assay kit from "Molecular Devices" was used to test whether these compounds were indeed direct inhibitors of the PD...				US Patent US8853226 (2014) BindingDB Entry DOI: 10.7270/Q28C9TZS
High Point Pharmaceuticals, LLC US Patent					More data for this Ligand-Target Pair

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* indicates data uncertainty>20%