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PubMed code 10386926

Compile data set for download or QSAR
Found 32 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Aminopeptidase N


(Sus scrofa (Pig))		BDBM50078122
PNG
((R)-1-{[(S)-2-((S)-1-Carboxy-1-methyl-2-phenyl-eth...)
Show SMILES C[C@@](Cc1ccccc1)(NC(=O)[C@H](Cc1ccccc1)CP(O)(=O)[C@@H]([NH3+])Cc1ccccc1)C(O)=O
Show InChI InChI=1S/C28H33N2O5P/c1-28(27(32)33,19-23-15-9-4-10-16-23)30-26(31)24(17-21-11-5-2-6-12-21)20-36(34,35)25(29)18-22-13-7-3-8-14-22/h2-16,24-25H,17-20,29H2,1H3,(H,30,31)(H,32,33)(H,34,35)/p+1/t24-,25-,28+/m1/s1
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 0n/an/an/an/an/an/an/an/a



INSERM

Curated by ChEMBL


Assay Description
Inhibitory activity was measured on pig kidney Aminopeptidase N (activity for C+D stereoisomer)

Bioorg Med Chem Lett 9: 1511-6 (1999)


BindingDB Entry DOI: 10.7270/Q2H132JR
More data for this
Ligand-Target Pair
Aminopeptidase B


(Mus musculus)		BDBM50078120
PNG
((R)-1-{[(S)-2-((S)-1-Carboxy-1-methyl-2-phenyl-eth...)
Show SMILES C[C@H]([NH3+])P(O)(=O)C[C@@H](Cc1ccccc1)C(=O)N[C@@](C)(Cc1ccccc1)C(O)=O
Show InChI InChI=1S/C22H29N2O5P/c1-16(23)30(28,29)15-19(13-17-9-5-3-6-10-17)20(25)24-22(2,21(26)27)14-18-11-7-4-8-12-18/h3-12,16,19H,13-15,23H2,1-2H3,(H,24,25)(H,26,27)(H,28,29)/p+1/t16-,19-,22+/m1/s1
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INSERM

Curated by ChEMBL


Assay Description
Inhibitory activity was measured on Aminopeptidase B using Arg p.NA as substrate

Bioorg Med Chem Lett 9: 1511-6 (1999)


BindingDB Entry DOI: 10.7270/Q2H132JR
More data for this
Ligand-Target Pair
Glutamyl aminopeptidase


(Sus scrofa)		BDBM50078122
PNG
((R)-1-{[(S)-2-((S)-1-Carboxy-1-methyl-2-phenyl-eth...)
Show SMILES C[C@@](Cc1ccccc1)(NC(=O)[C@H](Cc1ccccc1)CP(O)(=O)[C@@H]([NH3+])Cc1ccccc1)C(O)=O
Show InChI InChI=1S/C28H33N2O5P/c1-28(27(32)33,19-23-15-9-4-10-16-23)30-26(31)24(17-21-11-5-2-6-12-21)20-36(34,35)25(29)18-22-13-7-3-8-14-22/h2-16,24-25H,17-20,29H2,1H3,(H,30,31)(H,32,33)(H,34,35)/p+1/t24-,25-,28+/m1/s1
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 0n/an/an/an/an/an/an/an/a



INSERM

Curated by ChEMBL


Assay Description
Inhibitory activity was measured on Aminopeptidase using GluNA as substrate

Bioorg Med Chem Lett 9: 1511-6 (1999)


BindingDB Entry DOI: 10.7270/Q2H132JR
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))		BDBM50078120
PNG
((R)-1-{[(S)-2-((S)-1-Carboxy-1-methyl-2-phenyl-eth...)
Show SMILES C[C@H]([NH3+])P(O)(=O)C[C@@H](Cc1ccccc1)C(=O)N[C@@](C)(Cc1ccccc1)C(O)=O
Show InChI InChI=1S/C22H29N2O5P/c1-16(23)30(28,29)15-19(13-17-9-5-3-6-10-17)20(25)24-22(2,21(26)27)14-18-11-7-4-8-12-18/h3-12,16,19H,13-15,23H2,1-2H3,(H,24,25)(H,26,27)(H,28,29)/p+1/t16-,19-,22+/m1/s1
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 0n/an/an/an/an/an/an/an/a



INSERM

Curated by ChEMBL


Assay Description
Inhibitory activity was measured on pig kidney Aminopeptidase N (activity for C+D stereoisomer)

Bioorg Med Chem Lett 9: 1511-6 (1999)


BindingDB Entry DOI: 10.7270/Q2H132JR
More data for this
Ligand-Target Pair
Aminopeptidase B


(Mus musculus)		BDBM50078122
PNG
((R)-1-{[(S)-2-((S)-1-Carboxy-1-methyl-2-phenyl-eth...)
Show SMILES C[C@@](Cc1ccccc1)(NC(=O)[C@H](Cc1ccccc1)CP(O)(=O)[C@@H]([NH3+])Cc1ccccc1)C(O)=O
Show InChI InChI=1S/C28H33N2O5P/c1-28(27(32)33,19-23-15-9-4-10-16-23)30-26(31)24(17-21-11-5-2-6-12-21)20-36(34,35)25(29)18-22-13-7-3-8-14-22/h2-16,24-25H,17-20,29H2,1H3,(H,30,31)(H,32,33)(H,34,35)/p+1/t24-,25-,28+/m1/s1
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INSERM

Curated by ChEMBL


Assay Description
Inhibitory activity was measured on Aminopeptidase B using Arg p.NA as substrate

Bioorg Med Chem Lett 9: 1511-6 (1999)


BindingDB Entry DOI: 10.7270/Q2H132JR
More data for this
Ligand-Target Pair
Glutamyl aminopeptidase


(Sus scrofa)		BDBM50078120
PNG
((R)-1-{[(S)-2-((S)-1-Carboxy-1-methyl-2-phenyl-eth...)
Show SMILES C[C@H]([NH3+])P(O)(=O)C[C@@H](Cc1ccccc1)C(=O)N[C@@](C)(Cc1ccccc1)C(O)=O
Show InChI InChI=1S/C22H29N2O5P/c1-16(23)30(28,29)15-19(13-17-9-5-3-6-10-17)20(25)24-22(2,21(26)27)14-18-11-7-4-8-12-18/h3-12,16,19H,13-15,23H2,1-2H3,(H,24,25)(H,26,27)(H,28,29)/p+1/t16-,19-,22+/m1/s1
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 0n/an/an/an/an/an/an/an/a



INSERM

Curated by ChEMBL


Assay Description
Inhibitory activity was measured on pig kidney Aminopeptidase N (activity for A+B stereoisomer)

Bioorg Med Chem Lett 9: 1511-6 (1999)


BindingDB Entry DOI: 10.7270/Q2H132JR
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))		BDBM50087097
PNG
(1-{[2-(1-Carboxy-2-phenyl-ethylcarbamoyl)-3-phenyl...)
Show SMILES CC([NH3+])P(O)(=O)C[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(O)=O
Show InChI InChI=1S/C21H27N2O5P/c1-15(22)29(27,28)14-18(12-16-8-4-2-5-9-16)20(24)23-19(21(25)26)13-17-10-6-3-7-11-17/h2-11,15,18-19H,12-14,22H2,1H3,(H,23,24)(H,25,26)(H,27,28)/p+1/t15?,18-,19+/m1/s1
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 2.20n/an/an/an/an/an/an/an/a



INSERM

Curated by ChEMBL


Assay Description
Inhibitory activity was measured on pig kidney Aminopeptidase N (activity for A+B stereoisomer)

Bioorg Med Chem Lett 9: 1511-6 (1999)


BindingDB Entry DOI: 10.7270/Q2H132JR
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))		BDBM50078127
PNG
(2-{3-[(1-Amino-3-phenyl-propyl)-hydroxy-phosphinoy...)
Show SMILES OC(=O)C(Cc1ccccc1)NC(=O)C(Cc1ccccc1)CP(O)(O)C(=N)CCc1ccccc1
Show InChI InChI=1S/C28H33N2O5P/c29-26(17-16-21-10-4-1-5-11-21)36(34,35)20-24(18-22-12-6-2-7-13-22)27(31)30-25(28(32)33)19-23-14-8-3-9-15-23/h1-15,24-25,29,34-36H,16-20H2,(H,30,31)(H,32,33)
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 2.30n/an/an/an/an/an/an/an/a



INSERM

Curated by ChEMBL


Assay Description
Inhibitory activity was measured on pig kidney Aminopeptidase N (activity for A+B stereoisomer)

Bioorg Med Chem Lett 9: 1511-6 (1999)


BindingDB Entry DOI: 10.7270/Q2H132JR
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))		BDBM50078134
PNG
(2-{3-[(1-Amino-2-phenyl-ethyl)-hydroxy-phosphinoyl...)
Show SMILES OC(=O)C(Cc1ccccc1)NC(=O)C(Cc1ccccc1)CP(O)(O)C(=N)Cc1ccccc1
Show InChI InChI=1S/C27H31N2O5P/c28-25(18-22-14-8-3-9-15-22)35(33,34)19-23(16-20-10-4-1-5-11-20)26(30)29-24(27(31)32)17-21-12-6-2-7-13-21/h1-15,23-24,28,33-35H,16-19H2,(H,29,30)(H,31,32)
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 2.90n/an/an/an/an/an/an/an/a



INSERM

Curated by ChEMBL


Assay Description
Inhibitory activity was measured on pig kidney Aminopeptidase N (activity for A+B stereoisomer)

Bioorg Med Chem Lett 9: 1511-6 (1999)


BindingDB Entry DOI: 10.7270/Q2H132JR
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))		BDBM50078131
PNG
(2-{3-[(1-Amino-3-methyl-butyl)-hydroxy-phosphinoyl...)
Show SMILES CC(C)CC(=N)P(O)(O)CC(Cc1ccccc1)C(=O)NC(Cc1ccccc1)C(O)=O
Show InChI InChI=1S/C24H33N2O5P/c1-17(2)13-22(25)32(30,31)16-20(14-18-9-5-3-6-10-18)23(27)26-21(24(28)29)15-19-11-7-4-8-12-19/h3-12,17,20-21,25,30-32H,13-16H2,1-2H3,(H,26,27)(H,28,29)
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 3.20n/an/an/an/an/an/an/an/a



INSERM

Curated by ChEMBL


Assay Description
Inhibitory activity was measured on pig kidney Aminopeptidase N (activity for A+B stereoisomer)

Bioorg Med Chem Lett 9: 1511-6 (1999)


BindingDB Entry DOI: 10.7270/Q2H132JR
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))		BDBM50078135
PNG
(2-{3-[(Amino-phenyl-methyl)-hydroxy-phosphinoyl]-2...)
Show SMILES OC(=O)C(Cc1ccccc1)NC(=O)C(Cc1ccccc1)CP(O)(O)C(=N)c1ccccc1
Show InChI InChI=1S/C26H29N2O5P/c27-24(21-14-8-3-9-15-21)34(32,33)18-22(16-19-10-4-1-5-11-19)25(29)28-23(26(30)31)17-20-12-6-2-7-13-20/h1-15,22-23,27,32-34H,16-18H2,(H,28,29)(H,30,31)
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 3.80n/an/an/an/an/an/an/an/a



INSERM

Curated by ChEMBL


Assay Description
Inhibitory activity was measured on pig kidney Aminopeptidase N (activity for A+B stereoisomer)

Bioorg Med Chem Lett 9: 1511-6 (1999)


BindingDB Entry DOI: 10.7270/Q2H132JR
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))		BDBM50078137
PNG
(2-{3-[(1-Amino-3-methylsulfanyl-propyl)-hydroxy-ph...)
Show SMILES CSCCC(=N)P(O)(O)CC(Cc1ccccc1)C(=O)NC(Cc1ccccc1)C(O)=O
Show InChI InChI=1S/C23H31N2O5PS/c1-32-13-12-21(24)31(29,30)16-19(14-17-8-4-2-5-9-17)22(26)25-20(23(27)28)15-18-10-6-3-7-11-18/h2-11,19-20,24,29-31H,12-16H2,1H3,(H,25,26)(H,27,28)
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 6.30n/an/an/an/an/an/an/an/a



INSERM

Curated by ChEMBL


Assay Description
Inhibitory activity was measured on pig kidney Aminopeptidase N (activity for A+B stereoisomer)

Bioorg Med Chem Lett 9: 1511-6 (1999)


BindingDB Entry DOI: 10.7270/Q2H132JR
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))		BDBM50078128
PNG
((S)-2-Amino-4-methylsulfanyl-butane-1-thiol | CHEM...)
Show SMILES CSCC[C@H](N)CS
Show InChI InChI=1S/C5H13NS2/c1-8-3-2-5(6)4-7/h5,7H,2-4,6H2,1H3/t5-/m0/s1
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 11n/an/an/an/an/an/an/an/a



INSERM

Curated by ChEMBL


Assay Description
Inhibition of pig kidney Aminopeptidase N

Bioorg Med Chem Lett 9: 1511-6 (1999)


BindingDB Entry DOI: 10.7270/Q2H132JR
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))		BDBM50078133
PNG
((S)-2-Amino-4-methyl-pentane-1-thiol | 2-Amino-4-m...)
Show SMILES CC(C)C[C@H](N)CS
Show InChI InChI=1S/C6H15NS/c1-5(2)3-6(7)4-8/h5-6,8H,3-4,7H2,1-2H3/t6-/m0/s1
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 22n/an/an/an/an/an/an/an/a



INSERM

Curated by ChEMBL


Assay Description
Inhibition of pig kidney Aminopeptidase N

Bioorg Med Chem Lett 9: 1511-6 (1999)


BindingDB Entry DOI: 10.7270/Q2H132JR
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))		BDBM50078138
PNG
((S)-2-Amino-2-phenyl-ethanethiol | CHEMBL286865)
Show SMILES N[C@H](CS)c1ccccc1
Show InChI InChI=1S/C8H11NS/c9-8(6-10)7-4-2-1-3-5-7/h1-5,8,10H,6,9H2/t8-/m1/s1
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 25n/an/an/an/an/an/an/an/a



INSERM

Curated by ChEMBL


Assay Description
Inhibition of pig kidney Aminopeptidase N

Bioorg Med Chem Lett 9: 1511-6 (1999)


BindingDB Entry DOI: 10.7270/Q2H132JR
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))		BDBM50078121
PNG
((S)-2-Amino-4-phenyl-butane-1-thiol | CHEMBL34963)
Show SMILES N[C@H](CS)CCc1ccccc1
Show InChI InChI=1S/C10H15NS/c11-10(8-12)7-6-9-4-2-1-3-5-9/h1-5,10,12H,6-8,11H2/t10-/m0/s1
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 27n/an/an/an/an/an/an/an/a



INSERM

Curated by ChEMBL


Assay Description
Inhibition of pig kidney Aminopeptidase N

Bioorg Med Chem Lett 9: 1511-6 (1999)


BindingDB Entry DOI: 10.7270/Q2H132JR
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))		BDBM50078126
PNG
((S)-2-Amino-propane-1-thiol | CHEMBL37279)
Show SMILES C[C@H](N)CS
Show InChI InChI=1S/C3H9NS/c1-3(4)2-5/h3,5H,2,4H2,1H3/t3-/m0/s1
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 28n/an/an/an/an/an/an/an/a



INSERM

Curated by ChEMBL


Assay Description
Inhibition of pig kidney Aminopeptidase N

Bioorg Med Chem Lett 9: 1511-6 (1999)


BindingDB Entry DOI: 10.7270/Q2H132JR
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))		BDBM50078129
PNG
((S)-2-Amino-3-phenyl-propane-1-thiol | 2-Amino-3-p...)
Show SMILES N[C@H](CS)Cc1ccccc1
Show InChI InChI=1S/C9H13NS/c10-9(7-11)6-8-4-2-1-3-5-8/h1-5,9,11H,6-7,10H2/t9-/m0/s1
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 30n/an/an/an/an/an/an/an/a



INSERM

Curated by ChEMBL


Assay Description
Inhibition of pig kidney Aminopeptidase N

Bioorg Med Chem Lett 9: 1511-6 (1999)


BindingDB Entry DOI: 10.7270/Q2H132JR
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))		BDBM50078131
PNG
(2-{3-[(1-Amino-3-methyl-butyl)-hydroxy-phosphinoyl...)
Show SMILES CC(C)CC(=N)P(O)(O)CC(Cc1ccccc1)C(=O)NC(Cc1ccccc1)C(O)=O
Show InChI InChI=1S/C24H33N2O5P/c1-17(2)13-22(25)32(30,31)16-20(14-18-9-5-3-6-10-18)23(27)26-21(24(28)29)15-19-11-7-4-8-12-19/h3-12,17,20-21,25,30-32H,13-16H2,1-2H3,(H,26,27)(H,28,29)
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 90n/an/an/an/an/an/an/an/a



INSERM

Curated by ChEMBL


Assay Description
Inhibitory activity was measured on pig kidney Aminopeptidase N (activity for C+D stereoisomer)

Bioorg Med Chem Lett 9: 1511-6 (1999)


BindingDB Entry DOI: 10.7270/Q2H132JR
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))		BDBM50078125
PNG
((1-Amino-3-phenyl-propyl)-phosphinic acid | CHEMBL...)
Show SMILES OP(O)C(=N)CCc1ccccc1
Show InChI InChI=1S/C9H12NO2P/c10-9(13(11)12)7-6-8-4-2-1-3-5-8/h1-5,10-12H,6-7H2
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 130n/an/an/an/an/an/an/an/a



INSERM

Curated by ChEMBL


Assay Description
Inhibition of pig kidney Aminopeptidase N

Bioorg Med Chem Lett 9: 1511-6 (1999)


BindingDB Entry DOI: 10.7270/Q2H132JR
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))		BDBM21460
PNG
(3-[(1-amino-2-phenylethyl)(hydroxy)phosphoryl]-2-b...)
Show SMILES OC(=O)C(Cc1ccccc1)CP(O)(O)C(=N)Cc1ccccc1
Show InChI InChI=1S/C18H22NO4P/c19-17(12-15-9-5-2-6-10-15)24(22,23)13-16(18(20)21)11-14-7-3-1-4-8-14/h1-10,16,19,22-24H,11-13H2,(H,20,21)
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 190n/an/an/an/an/an/an/an/a



INSERM

Curated by ChEMBL


Assay Description
Inhibition of pig kidney Aminopeptidase N

Bioorg Med Chem Lett 9: 1511-6 (1999)


BindingDB Entry DOI: 10.7270/Q2H132JR
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))		BDBM50078134
PNG
(2-{3-[(1-Amino-2-phenyl-ethyl)-hydroxy-phosphinoyl...)
Show SMILES OC(=O)C(Cc1ccccc1)NC(=O)C(Cc1ccccc1)CP(O)(O)C(=N)Cc1ccccc1
Show InChI InChI=1S/C27H31N2O5P/c28-25(18-22-14-8-3-9-15-22)35(33,34)19-23(16-20-10-4-1-5-11-20)26(30)29-24(27(31)32)17-21-12-6-2-7-13-21/h1-15,23-24,28,33-35H,16-19H2,(H,29,30)(H,31,32)
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 200n/an/an/an/an/an/an/an/a



INSERM

Curated by ChEMBL


Assay Description
Inhibitory activity was measured on pig kidney Aminopeptidase N (activity for C+D stereoisomer)

Bioorg Med Chem Lett 9: 1511-6 (1999)


BindingDB Entry DOI: 10.7270/Q2H132JR
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))		BDBM50078135
PNG
(2-{3-[(Amino-phenyl-methyl)-hydroxy-phosphinoyl]-2...)
Show SMILES OC(=O)C(Cc1ccccc1)NC(=O)C(Cc1ccccc1)CP(O)(O)C(=N)c1ccccc1
Show InChI InChI=1S/C26H29N2O5P/c27-24(21-14-8-3-9-15-21)34(32,33)18-22(16-19-10-4-1-5-11-19)25(29)28-23(26(30)31)17-20-12-6-2-7-13-20/h1-15,22-23,27,32-34H,16-18H2,(H,28,29)(H,30,31)
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 320n/an/an/an/an/an/an/an/a



INSERM

Curated by ChEMBL


Assay Description
Inhibitory activity was measured on pig kidney Aminopeptidase N (activity for C+D stereoisomer)

Bioorg Med Chem Lett 9: 1511-6 (1999)


BindingDB Entry DOI: 10.7270/Q2H132JR
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))		BDBM50078127
PNG
(2-{3-[(1-Amino-3-phenyl-propyl)-hydroxy-phosphinoy...)
Show SMILES OC(=O)C(Cc1ccccc1)NC(=O)C(Cc1ccccc1)CP(O)(O)C(=N)CCc1ccccc1
Show InChI InChI=1S/C28H33N2O5P/c29-26(17-16-21-10-4-1-5-11-21)36(34,35)20-24(18-22-12-6-2-7-13-22)27(31)30-25(28(32)33)19-23-14-8-3-9-15-23/h1-15,24-25,29,34-36H,16-20H2,(H,30,31)(H,32,33)
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 360n/an/an/an/an/an/an/an/a



INSERM

Curated by ChEMBL


Assay Description
Inhibitory activity was measured on pig kidney Aminopeptidase N (activity for C+D stereoisomer)

Bioorg Med Chem Lett 9: 1511-6 (1999)


BindingDB Entry DOI: 10.7270/Q2H132JR
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))		BDBM21461
PNG
(3-[(1-amino-3-methylbutyl)(hydroxy)phosphoryl]-2-b...)
Show SMILES CC(C)CC(=N)P(O)(O)CC(Cc1ccccc1)C(O)=O
Show InChI InChI=1S/C15H24NO4P/c1-11(2)8-14(16)21(19,20)10-13(15(17)18)9-12-6-4-3-5-7-12/h3-7,11,13,16,19-21H,8-10H2,1-2H3,(H,17,18)
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 370n/an/an/an/an/an/an/an/a



INSERM

Curated by ChEMBL


Assay Description
Inhibition of pig kidney Aminopeptidase N

Bioorg Med Chem Lett 9: 1511-6 (1999)


BindingDB Entry DOI: 10.7270/Q2H132JR
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))		BDBM50078137
PNG
(2-{3-[(1-Amino-3-methylsulfanyl-propyl)-hydroxy-ph...)
Show SMILES CSCCC(=N)P(O)(O)CC(Cc1ccccc1)C(=O)NC(Cc1ccccc1)C(O)=O
Show InChI InChI=1S/C23H31N2O5PS/c1-32-13-12-21(24)31(29,30)16-19(14-17-8-4-2-5-9-17)22(26)25-20(23(27)28)15-18-10-6-3-7-11-18/h2-11,19-20,24,29-31H,12-16H2,1H3,(H,25,26)(H,27,28)
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 370n/an/an/an/an/an/an/an/a



INSERM

Curated by ChEMBL


Assay Description
Inhibitory activity was measured on pig kidney Aminopeptidase N (activity for C+D stereoisomer)

Bioorg Med Chem Lett 9: 1511-6 (1999)


BindingDB Entry DOI: 10.7270/Q2H132JR
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))		BDBM50078130
PNG
((1-Amino-3-methylsulfanyl-propyl)-phosphinic acid ...)
Show SMILES CSCCC(=N)P(O)O
Show InChI InChI=1S/C4H10NO2PS/c1-9-3-2-4(5)8(6)7/h5-7H,2-3H2,1H3
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 400n/an/an/an/an/an/an/an/a



INSERM

Curated by ChEMBL


Assay Description
Inhibition of pig kidney Aminopeptidase N

Bioorg Med Chem Lett 9: 1511-6 (1999)


BindingDB Entry DOI: 10.7270/Q2H132JR
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))		BDBM50087097
PNG
(1-{[2-(1-Carboxy-2-phenyl-ethylcarbamoyl)-3-phenyl...)
Show SMILES CC([NH3+])P(O)(=O)C[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(O)=O
Show InChI InChI=1S/C21H27N2O5P/c1-15(22)29(27,28)14-18(12-16-8-4-2-5-9-16)20(24)23-19(21(25)26)13-17-10-6-3-7-11-17/h2-11,15,18-19H,12-14,22H2,1H3,(H,23,24)(H,25,26)(H,27,28)/p+1/t15?,18-,19+/m1/s1
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 670n/an/an/an/an/an/an/an/a



INSERM

Curated by ChEMBL


Assay Description
Inhibitory activity was measured on pig kidney Aminopeptidase N (activity for C+D stereoisomer)

Bioorg Med Chem Lett 9: 1511-6 (1999)


BindingDB Entry DOI: 10.7270/Q2H132JR
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))		BDBM50078139
PNG
((1-Amino-2-phenyl-ethyl)-phosphinic acid | (1-Ammo...)
Show SMILES OP(O)C(=N)Cc1ccccc1
Show InChI InChI=1S/C8H10NO2P/c9-8(12(10)11)6-7-4-2-1-3-5-7/h1-5,9-11H,6H2
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 960n/an/an/an/an/an/an/an/a



INSERM

Curated by ChEMBL


Assay Description
Inhibition of pig kidney Aminopeptidase N

Bioorg Med Chem Lett 9: 1511-6 (1999)


BindingDB Entry DOI: 10.7270/Q2H132JR
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))		BDBM50078132
PNG
((1-Amino-3-methyl-butyl)-phosphinic acid | (1-Ammo...)
Show SMILES CC(C)CC(=N)P(O)O
Show InChI InChI=1S/C5H12NO2P/c1-4(2)3-5(6)9(7)8/h4,6-8H,3H2,1-2H3
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 1.20E+3n/an/an/an/an/an/an/an/a



INSERM

Curated by ChEMBL


Assay Description
Inhibition of pig kidney Aminopeptidase N

Bioorg Med Chem Lett 9: 1511-6 (1999)


BindingDB Entry DOI: 10.7270/Q2H132JR
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))		BDBM50078136
PNG
((Amino-phenyl-methyl)-phosphinic acid | CHEMBL3997...)
Show SMILES OP(O)C(=N)c1ccccc1
Show InChI InChI=1S/C7H8NO2P/c8-7(11(9)10)6-4-2-1-3-5-6/h1-5,8-10H
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 4.80E+3n/an/an/an/an/an/an/an/a



INSERM

Curated by ChEMBL


Assay Description
Inhibition of pig kidney Aminopeptidase N

Bioorg Med Chem Lett 9: 1511-6 (1999)


BindingDB Entry DOI: 10.7270/Q2H132JR
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))		BDBM50078124
PNG
((1-Amino-ethyl)-phosphinic acid | CHEMBL37702)
Show SMILES CC(=N)P(O)O
Show InChI InChI=1S/C2H6NO2P/c1-2(3)6(4)5/h3-5H,1H3
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 8.40E+3n/an/an/an/an/an/an/an/a



INSERM

Curated by ChEMBL


Assay Description
Inhibition of pig kidney Aminopeptidase N

Bioorg Med Chem Lett 9: 1511-6 (1999)


BindingDB Entry DOI: 10.7270/Q2H132JR
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%