Affinity Data by PubMed id=16632353

PubMed code 16632353

Found 14 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Methionine aminopeptidase 2 (Homo sapiens (Human))	BDBM17478 (2-benzenesulfonamido-5,6,7,8-tetrahydronaphthalene...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	DrugBank MMDB PC cid PC sid PDB UniChem Patents Similars	MMDB PDB Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	7.4	22
Abbott Laboratories					Assay Description A coupled enzyme chromogenic assay was developed to measure methionine aminopeptidase-2 activity by monitoring the production of free methionine with...				Bioorg Med Chem Lett 16: 3574-7 (2006) Article DOI: 10.1016/j.bmcl.2006.03.085 BindingDB Entry DOI: 10.7270/Q2TB1556
Abbott Laboratories					More data for this Ligand-Target Pair				3D Structure (crystal)
Methionine aminopeptidase 2 (Homo sapiens (Human))	BDBM17607 (2-[(4-fluorobenzene)sulfonamido]-5,6,7,8-tetrahydr...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	7.4	22
Abbott Laboratories					Assay Description A coupled enzyme chromogenic assay was developed to measure methionine aminopeptidase-2 activity by monitoring the production of free methionine with...				Bioorg Med Chem Lett 16: 3574-7 (2006) Article DOI: 10.1016/j.bmcl.2006.03.085 BindingDB Entry DOI: 10.7270/Q2TB1556
Abbott Laboratories					More data for this Ligand-Target Pair
Methionine aminopeptidase 2 (Homo sapiens (Human))	BDBM17604 (2-[(4-fluorobenzene)sulfonamido]naphthalene-1-carb...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	7.4	22
Abbott Laboratories					Assay Description A coupled enzyme chromogenic assay was developed to measure methionine aminopeptidase-2 activity by monitoring the production of free methionine with...				Bioorg Med Chem Lett 16: 3574-7 (2006) Article DOI: 10.1016/j.bmcl.2006.03.085 BindingDB Entry DOI: 10.7270/Q2TB1556
Abbott Laboratories					More data for this Ligand-Target Pair
Methionine aminopeptidase 2 (Homo sapiens (Human))	BDBM17603 (2-benzenesulfonamidonaphthalene-1-carboxylic acid ...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	7.4	22
Abbott Laboratories					Assay Description A coupled enzyme chromogenic assay was developed to measure methionine aminopeptidase-2 activity by monitoring the production of free methionine with...				Bioorg Med Chem Lett 16: 3574-7 (2006) Article DOI: 10.1016/j.bmcl.2006.03.085 BindingDB Entry DOI: 10.7270/Q2TB1556
Abbott Laboratories					More data for this Ligand-Target Pair
Methionine aminopeptidase 2 (Homo sapiens (Human))	BDBM17606 (2-[(4-fluorobenzene)sulfonamido]-8-methyl-5,6-dihy...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	7.4	22
Abbott Laboratories					Assay Description A coupled enzyme chromogenic assay was developed to measure methionine aminopeptidase-2 activity by monitoring the production of free methionine with...				Bioorg Med Chem Lett 16: 3574-7 (2006) Article DOI: 10.1016/j.bmcl.2006.03.085 BindingDB Entry DOI: 10.7270/Q2TB1556
Abbott Laboratories					More data for this Ligand-Target Pair
Methionine aminopeptidase 2 (Homo sapiens (Human))	BDBM17608 ((8S)-2-[(4-fluorobenzene)sulfonamido]-8-methyl-5,6...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	27	n/a	n/a	n/a	n/a	7.4	22
Abbott Laboratories					Assay Description A coupled enzyme chromogenic assay was developed to measure methionine aminopeptidase-2 activity by monitoring the production of free methionine with...				Bioorg Med Chem Lett 16: 3574-7 (2006) Article DOI: 10.1016/j.bmcl.2006.03.085 BindingDB Entry DOI: 10.7270/Q2TB1556
Abbott Laboratories					More data for this Ligand-Target Pair
Methionine aminopeptidase 2 (Homo sapiens (Human))	BDBM17600 (2-benzenesulfonamido-5-ethylbenzoic acid \| sulfona...) Show SMILES CCc1ccc(NS(=O)(=O)c2ccccc2)c(c1)C(O)=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	7.4	22
Abbott Laboratories					Assay Description A coupled enzyme chromogenic assay was developed to measure methionine aminopeptidase-2 activity by monitoring the production of free methionine with...				Bioorg Med Chem Lett 16: 3574-7 (2006) Article DOI: 10.1016/j.bmcl.2006.03.085 BindingDB Entry DOI: 10.7270/Q2TB1556
Abbott Laboratories					More data for this Ligand-Target Pair
Methionine aminopeptidase 2 (Homo sapiens (Human))	BDBM17599 (2-benzenesulfonamido-3,5-dimethylbenzoic acid \| su...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	350	n/a	n/a	n/a	n/a	7.4	22
Abbott Laboratories					Assay Description A coupled enzyme chromogenic assay was developed to measure methionine aminopeptidase-2 activity by monitoring the production of free methionine with...				Bioorg Med Chem Lett 16: 3574-7 (2006) Article DOI: 10.1016/j.bmcl.2006.03.085 BindingDB Entry DOI: 10.7270/Q2TB1556
Abbott Laboratories					More data for this Ligand-Target Pair
Methionine aminopeptidase 2 (Homo sapiens (Human))	BDBM17477 (2-benzenesulfonamido-5-methylbenzoic acid \| A44414...) Show SMILES Cc1ccc(NS(=O)(=O)c2ccccc2)c(c1)C(O)=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MMDB PC cid PC sid PDB UniChem Patents Similars	MMDB PDB Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	7.4	22
Abbott Laboratories					Assay Description A coupled enzyme chromogenic assay was developed to measure methionine aminopeptidase-2 activity by monitoring the production of free methionine with...				Bioorg Med Chem Lett 16: 3574-7 (2006) Article DOI: 10.1016/j.bmcl.2006.03.085 BindingDB Entry DOI: 10.7270/Q2TB1556
Abbott Laboratories					More data for this Ligand-Target Pair				3D Structure (crystal)
Methionine aminopeptidase 2 (Homo sapiens (Human))	BDBM17601 (2-benzenesulfonamido-5-propylbenzoic acid \| sulfon...) Show SMILES CCCc1ccc(NS(=O)(=O)c2ccccc2)c(c1)C(O)=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	7.4	22
Abbott Laboratories					Assay Description A coupled enzyme chromogenic assay was developed to measure methionine aminopeptidase-2 activity by monitoring the production of free methionine with...				Bioorg Med Chem Lett 16: 3574-7 (2006) Article DOI: 10.1016/j.bmcl.2006.03.085 BindingDB Entry DOI: 10.7270/Q2TB1556
Abbott Laboratories					More data for this Ligand-Target Pair
Methionine aminopeptidase 2 (Homo sapiens (Human))	BDBM17596 (2-(2,1,3-benzothiadiazole-4-sulfonamido)-5-bromobe...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	3.90E+3	n/a	n/a	n/a	n/a	7.4	22
Abbott Laboratories					Assay Description A coupled enzyme chromogenic assay was developed to measure methionine aminopeptidase-2 activity by monitoring the production of free methionine with...				Bioorg Med Chem Lett 16: 3574-7 (2006) Article DOI: 10.1016/j.bmcl.2006.03.085 BindingDB Entry DOI: 10.7270/Q2TB1556
Abbott Laboratories					More data for this Ligand-Target Pair
Methionine aminopeptidase 2 (Homo sapiens (Human))	BDBM17595 (5-bromo-2-[(4-chlorobenzene)sulfonamido]benzoic ac...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MMDB PC cid PC sid PDB UniChem Patents Similars	MMDB PDB Article PubMed	n/a	n/a	9.10E+3	n/a	n/a	n/a	n/a	7.4	22
Abbott Laboratories					Assay Description A coupled enzyme chromogenic assay was developed to measure methionine aminopeptidase-2 activity by monitoring the production of free methionine with...				Bioorg Med Chem Lett 16: 3574-7 (2006) Article DOI: 10.1016/j.bmcl.2006.03.085 BindingDB Entry DOI: 10.7270/Q2TB1556
Abbott Laboratories					More data for this Ligand-Target Pair				3D Structure (crystal)
Methionine aminopeptidase 2 (Homo sapiens (Human))	BDBM17602 (2-benzenesulfonamido-5-butylbenzoic acid \| sulfona...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	7.4	22
Abbott Laboratories					Assay Description A coupled enzyme chromogenic assay was developed to measure methionine aminopeptidase-2 activity by monitoring the production of free methionine with...				Bioorg Med Chem Lett 16: 3574-7 (2006) Article DOI: 10.1016/j.bmcl.2006.03.085 BindingDB Entry DOI: 10.7270/Q2TB1556
Abbott Laboratories					More data for this Ligand-Target Pair
Methionine aminopeptidase 2 (Homo sapiens (Human))	BDBM17597 (2-[(4-chlorobenzene)sulfonamido]-5-methylbenzoic a...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	7.4	22
Abbott Laboratories					Assay Description A coupled enzyme chromogenic assay was developed to measure methionine aminopeptidase-2 activity by monitoring the production of free methionine with...				Bioorg Med Chem Lett 16: 3574-7 (2006) Article DOI: 10.1016/j.bmcl.2006.03.085 BindingDB Entry DOI: 10.7270/Q2TB1556
Abbott Laboratories					More data for this Ligand-Target Pair

* indicates data uncertainty>20%