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PubMed code 17416521

Compile data set for download or QSAR
Found 67 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Oxysterols receptor LXR-beta


(Homo sapiens (Human))		BDBM27302
PNG
(N-(5-{1-[3-(benzyloxy)propyl]-1H-indol-2-yl}-2,3-d...)
Show SMILES O=S(=O)(NC1Cc2ccc(cc2C1)-c1cc2ccccc2n1CCCOCc1ccccc1)c1ccccc1
Show InChI InChI=1S/C33H32N2O3S/c36-39(37,31-13-5-2-6-14-31)34-30-21-26-16-17-28(20-29(26)22-30)33-23-27-12-7-8-15-32(27)35(33)18-9-19-38-24-25-10-3-1-4-11-25/h1-8,10-17,20,23,30,34H,9,18-19,21-22,24H2
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n/an/an/an/a>3.00E+4n/an/a7.522



Tanabe Research Laboratories USA



Assay Description
Polyhistidine-tagged human LXR ligand-binding domain was mixed with the test compound, biotin-SRC1 peptide, streptavidin-allophycocyanin, and europiu...

Bioorg Med Chem Lett 17: 3473-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.03.076
BindingDB Entry DOI: 10.7270/Q2HD7T00
More data for this
Ligand-Target Pair
Oxysterols receptor LXR-beta


(Homo sapiens (Human))		BDBM27315
PNG
(indole derivative, 5j | tert-butyl 2-(2-{[2-(metho...)
Show SMILES COC(=O)c1ccccc1S(=O)(=O)NC1Cc2ccc(cc2C1)-c1cc2ccccc2n1C(=O)OC(C)(C)C
Show InChI InChI=1S/C30H30N2O6S/c1-30(2,3)38-29(34)32-25-11-7-5-9-20(25)18-26(32)21-14-13-19-16-23(17-22(19)15-21)31-39(35,36)27-12-8-6-10-24(27)28(33)37-4/h5-15,18,23,31H,16-17H2,1-4H3
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n/an/an/an/a 600n/an/an/an/a



Tanabe Research Laboratories USA



Assay Description
Polyhistidine-tagged human LXR ligand-binding domain was mixed with the test compound, biotin-SRC1 peptide, streptavidin-allophycocyanin, and europiu...

Bioorg Med Chem Lett 17: 3473-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.03.076
BindingDB Entry DOI: 10.7270/Q2HD7T00
More data for this
Ligand-Target Pair
Oxysterols receptor LXR-beta


(Homo sapiens (Human))		BDBM27327
PNG
(indole derivative, 5v | tert-butyl 2-{2-[(4-phenyl...)
Show SMILES CC(C)(C)OC(=O)n1c(cc2ccccc12)-c1ccc2CC(Cc2c1)NS(=O)(=O)c1ccc(cc1)-c1ccccc1
Show InChI InChI=1S/C34H32N2O4S/c1-34(2,3)40-33(37)36-31-12-8-7-11-26(31)22-32(36)27-14-13-25-20-29(21-28(25)19-27)35-41(38,39)30-17-15-24(16-18-30)23-9-5-4-6-10-23/h4-19,22,29,35H,20-21H2,1-3H3
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n/an/an/an/a 2.10E+3n/an/an/an/a



Tanabe Research Laboratories USA



Assay Description
Polyhistidine-tagged human LXR ligand-binding domain was mixed with the test compound, biotin-SRC1 peptide, streptavidin-allophycocyanin, and europiu...

Bioorg Med Chem Lett 17: 3473-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.03.076
BindingDB Entry DOI: 10.7270/Q2HD7T00
More data for this
Ligand-Target Pair
Oxysterols receptor LXR-alpha


(Homo sapiens (Human))		BDBM27322
PNG
(indole derivative, 5q | tert-butyl 2-{2-[(2,6-difl...)
Show SMILES CC(C)(C)OC(=O)n1c(cc2ccccc12)-c1ccc2CC(Cc2c1)NS(=O)(=O)c1c(F)cccc1F
Show InChI InChI=1S/C28H26F2N2O4S/c1-28(2,3)36-27(33)32-24-10-5-4-7-18(24)16-25(32)19-12-11-17-14-21(15-20(17)13-19)31-37(34,35)26-22(29)8-6-9-23(26)30/h4-13,16,21,31H,14-15H2,1-3H3
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n/an/an/an/a 570n/an/an/an/a



Tanabe Research Laboratories USA



Assay Description
Polyhistidine-tagged human LXR ligand-binding domain was mixed with the test compound, biotin-SRC1 peptide, streptavidin-allophycocyanin, and europiu...

Bioorg Med Chem Lett 17: 3473-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.03.076
BindingDB Entry DOI: 10.7270/Q2HD7T00
More data for this
Ligand-Target Pair
Oxysterols receptor LXR-beta


(Homo sapiens (Human))		BDBM27334
PNG
(indole derivative, 40 | tert-butyl 2-{2-[(2-hydrox...)
Show SMILES CC(C)(C)OC(=O)n1c(cc2ccccc12)-c1ccc2CC(Cc2c1)NC(=O)c1ccccc1O
Show InChI InChI=1S/C29H28N2O4/c1-29(2,3)35-28(34)31-24-10-6-4-8-19(24)17-25(31)20-13-12-18-15-22(16-21(18)14-20)30-27(33)23-9-5-7-11-26(23)32/h4-14,17,22,32H,15-16H2,1-3H3,(H,30,33)
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n/an/an/an/a 530n/an/an/an/a



Tanabe Research Laboratories USA



Assay Description
Polyhistidine-tagged human LXR ligand-binding domain was mixed with the test compound, biotin-SRC1 peptide, streptavidin-allophycocyanin, and europiu...

Bioorg Med Chem Lett 17: 3473-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.03.076
BindingDB Entry DOI: 10.7270/Q2HD7T00
More data for this
Ligand-Target Pair
Oxysterols receptor LXR-beta


(Homo sapiens (Human))		BDBM27288
PNG
(indole derivative, 1n (S) | tert-butyl 2-[(2S)-2-b...)
Show SMILES CC(C)(C)OC(=O)n1c(cc2ccccc12)-c1ccc2C[C@@H](Cc2c1)NS(=O)(=O)c1ccccc1 |r|
Show InChI InChI=1S/C28H28N2O4S/c1-28(2,3)34-27(31)30-25-12-8-7-9-20(25)18-26(30)21-14-13-19-16-23(17-22(19)15-21)29-35(32,33)24-10-5-4-6-11-24/h4-15,18,23,29H,16-17H2,1-3H3/t23-/m0/s1
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n/an/an/an/a 130n/an/a7.522



Tanabe Research Laboratories USA



Assay Description
Polyhistidine-tagged human LXR ligand-binding domain was mixed with the test compound, biotin-SRC1 peptide, streptavidin-allophycocyanin, and europiu...

Bioorg Med Chem Lett 17: 3473-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.03.076
BindingDB Entry DOI: 10.7270/Q2HD7T00
More data for this
Ligand-Target Pair
Oxysterols receptor LXR-beta


(Homo sapiens (Human))		BDBM27296
PNG
(N-{5-[1-(2-cyclopropylacetyl)-1H-indol-2-yl]-2,3-d...)
Show SMILES O=C(CC1CC1)n1c(cc2ccccc12)-c1ccc2CC(Cc2c1)NS(=O)(=O)c1ccccc1
Show InChI InChI=1S/C28H26N2O3S/c31-28(14-19-10-11-19)30-26-9-5-4-6-21(26)18-27(30)22-13-12-20-16-24(17-23(20)15-22)29-34(32,33)25-7-2-1-3-8-25/h1-9,12-13,15,18-19,24,29H,10-11,14,16-17H2
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n/an/an/an/a 1.16E+3n/an/a7.522



Tanabe Research Laboratories USA



Assay Description
Polyhistidine-tagged human LXR ligand-binding domain was mixed with the test compound, biotin-SRC1 peptide, streptavidin-allophycocyanin, and europiu...

Bioorg Med Chem Lett 17: 3473-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.03.076
BindingDB Entry DOI: 10.7270/Q2HD7T00
More data for this
Ligand-Target Pair
Oxysterols receptor LXR-beta


(Homo sapiens (Human))		BDBM27304
PNG
(N-(5-{1-[(4-methoxyphenyl)methyl]-1H-indol-2-yl}-2...)
Show SMILES COc1ccc(Cn2c(cc3ccccc23)-c2ccc3CC(Cc3c2)NS(=O)(=O)c2ccccc2)cc1
Show InChI InChI=1S/C31H28N2O3S/c1-36-28-15-11-22(12-16-28)21-33-30-10-6-5-7-24(30)20-31(33)25-14-13-23-18-27(19-26(23)17-25)32-37(34,35)29-8-3-2-4-9-29/h2-17,20,27,32H,18-19,21H2,1H3
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n/an/an/an/a>3.00E+4n/an/an/an/a



Tanabe Research Laboratories USA



Assay Description
Polyhistidine-tagged human LXR ligand-binding domain was mixed with the test compound, biotin-SRC1 peptide, streptavidin-allophycocyanin, and europiu...

Bioorg Med Chem Lett 17: 3473-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.03.076
BindingDB Entry DOI: 10.7270/Q2HD7T00
More data for this
Ligand-Target Pair
Oxysterols receptor LXR-beta


(Homo sapiens (Human))		BDBM27320
PNG
(indole derivative, 5o | tert-butyl 2-{2-[(2-cyanob...)
Show SMILES CC(C)(C)OC(=O)n1c(cc2ccccc12)-c1ccc2CC(Cc2c1)NS(=O)(=O)c1ccccc1C#N
Show InChI InChI=1S/C29H27N3O4S/c1-29(2,3)36-28(33)32-25-10-6-4-8-20(25)17-26(32)21-13-12-19-15-24(16-23(19)14-21)31-37(34,35)27-11-7-5-9-22(27)18-30/h4-14,17,24,31H,15-16H2,1-3H3
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n/an/an/an/a 60n/an/an/an/a



Tanabe Research Laboratories USA



Assay Description
Polyhistidine-tagged human LXR ligand-binding domain was mixed with the test compound, biotin-SRC1 peptide, streptavidin-allophycocyanin, and europiu...

Bioorg Med Chem Lett 17: 3473-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.03.076
BindingDB Entry DOI: 10.7270/Q2HD7T00
More data for this
Ligand-Target Pair
Oxysterols receptor LXR-beta


(Homo sapiens (Human))		BDBM27321
PNG
(indole derivative, 5p | tert-butyl 2-{2-[(2-fluoro...)
Show SMILES CC(C)(C)OC(=O)n1c(cc2ccccc12)-c1ccc2CC(Cc2c1)NS(=O)(=O)c1ccccc1F
Show InChI InChI=1S/C28H27FN2O4S/c1-28(2,3)35-27(32)31-24-10-6-4-8-19(24)17-25(31)20-13-12-18-15-22(16-21(18)14-20)30-36(33,34)26-11-7-5-9-23(26)29/h4-14,17,22,30H,15-16H2,1-3H3
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n/an/an/an/a 100n/an/an/an/a



Tanabe Research Laboratories USA



Assay Description
Polyhistidine-tagged human LXR ligand-binding domain was mixed with the test compound, biotin-SRC1 peptide, streptavidin-allophycocyanin, and europiu...

Bioorg Med Chem Lett 17: 3473-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.03.076
BindingDB Entry DOI: 10.7270/Q2HD7T00
More data for this
Ligand-Target Pair
Oxysterols receptor LXR-alpha


(Homo sapiens (Human))		BDBM27307
PNG
(indole derivative, 5b | tert-butyl 2-{2-[(4-fluoro...)
Show SMILES CC(C)(C)OC(=O)n1c(cc2ccccc12)-c1ccc2CC(Cc2c1)NS(=O)(=O)c1ccc(F)cc1
Show InChI InChI=1S/C28H27FN2O4S/c1-28(2,3)35-27(32)31-25-7-5-4-6-19(25)17-26(31)20-9-8-18-15-23(16-21(18)14-20)30-36(33,34)24-12-10-22(29)11-13-24/h4-14,17,23,30H,15-16H2,1-3H3
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n/an/an/an/a 4.30E+3n/an/an/an/a



Tanabe Research Laboratories USA



Assay Description
Polyhistidine-tagged human LXR ligand-binding domain was mixed with the test compound, biotin-SRC1 peptide, streptavidin-allophycocyanin, and europiu...

Bioorg Med Chem Lett 17: 3473-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.03.076
BindingDB Entry DOI: 10.7270/Q2HD7T00
More data for this
Ligand-Target Pair
Oxysterols receptor LXR-alpha


(Homo sapiens (Human))		BDBM27324
PNG
(indole derivative, 5s | tert-butyl 2-[2-(thiophene...)
Show SMILES CC(C)(C)OC(=O)n1c(cc2ccccc12)-c1ccc2CC(Cc2c1)NS(=O)(=O)c1cccs1
Show InChI InChI=1S/C26H26N2O4S2/c1-26(2,3)32-25(29)28-22-8-5-4-7-18(22)16-23(28)19-11-10-17-14-21(15-20(17)13-19)27-34(30,31)24-9-6-12-33-24/h4-13,16,21,27H,14-15H2,1-3H3
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n/an/an/an/a 540n/an/an/an/a



Tanabe Research Laboratories USA



Assay Description
Polyhistidine-tagged human LXR ligand-binding domain was mixed with the test compound, biotin-SRC1 peptide, streptavidin-allophycocyanin, and europiu...

Bioorg Med Chem Lett 17: 3473-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.03.076
BindingDB Entry DOI: 10.7270/Q2HD7T00
More data for this
Ligand-Target Pair
Oxysterols receptor LXR-beta


(Homo sapiens (Human))		BDBM27278
PNG
(indole derivative, 1d | tert-butyl 2-(2-benzenesul...)
Show SMILES CC(C)(C)OC(=O)n1c(cc2cc(OCc3ccccc3)ccc12)-c1ccc2CC(Cc2c1)NS(=O)(=O)c1ccccc1
Show InChI InChI=1S/C35H34N2O5S/c1-35(2,3)42-34(38)37-32-17-16-30(41-23-24-10-6-4-7-11-24)21-28(32)22-33(37)26-15-14-25-19-29(20-27(25)18-26)36-43(39,40)31-12-8-5-9-13-31/h4-18,21-22,29,36H,19-20,23H2,1-3H3
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n/an/an/an/a>3.00E+4n/an/a7.522



Tanabe Research Laboratories USA



Assay Description
Polyhistidine-tagged human LXR ligand-binding domain was mixed with the test compound, biotin-SRC1 peptide, streptavidin-allophycocyanin, and europiu...

Bioorg Med Chem Lett 17: 3473-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.03.076
BindingDB Entry DOI: 10.7270/Q2HD7T00
More data for this
Ligand-Target Pair
Oxysterols receptor LXR-beta


(Homo sapiens (Human))		BDBM27280
PNG
(indole derivative, 1f | tert-butyl 2-(2-benzenesul...)
Show SMILES CC(C)(C)OC(=O)n1c(cc2cc(ccc12)C#N)-c1ccc2CC(Cc2c1)NS(=O)(=O)c1ccccc1
Show InChI InChI=1S/C29H27N3O4S/c1-29(2,3)36-28(33)32-26-12-9-19(18-30)13-23(26)17-27(32)21-11-10-20-15-24(16-22(20)14-21)31-37(34,35)25-7-5-4-6-8-25/h4-14,17,24,31H,15-16H2,1-3H3
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n/an/an/an/a 2.60E+4n/an/a7.522



Tanabe Research Laboratories USA



Assay Description
Polyhistidine-tagged human LXR ligand-binding domain was mixed with the test compound, biotin-SRC1 peptide, streptavidin-allophycocyanin, and europiu...

Bioorg Med Chem Lett 17: 3473-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.03.076
BindingDB Entry DOI: 10.7270/Q2HD7T00
More data for this
Ligand-Target Pair
Oxysterols receptor LXR-beta


(Homo sapiens (Human))		BDBM27285
PNG
(indole derivative, 1k | tert-butyl 2-(2-benzenesul...)
Show SMILES Cc1ccc2cc(-c3ccc4CC(Cc4c3)NS(=O)(=O)c3ccccc3)n(C(=O)OC(C)(C)C)c2c1
Show InChI InChI=1S/C29H30N2O4S/c1-19-10-11-22-18-27(31(26(22)14-19)28(32)35-29(2,3)4)21-13-12-20-16-24(17-23(20)15-21)30-36(33,34)25-8-6-5-7-9-25/h5-15,18,24,30H,16-17H2,1-4H3
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n/an/an/an/a 300n/an/a7.522



Tanabe Research Laboratories USA



Assay Description
Polyhistidine-tagged human LXR ligand-binding domain was mixed with the test compound, biotin-SRC1 peptide, streptavidin-allophycocyanin, and europiu...

Bioorg Med Chem Lett 17: 3473-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.03.076
BindingDB Entry DOI: 10.7270/Q2HD7T00
More data for this
Ligand-Target Pair
Oxysterols receptor LXR-beta


(Homo sapiens (Human))		BDBM27290
PNG
(indole derivative, 12 | methyl 2-(2-benzenesulfona...)
Show SMILES COC(=O)n1c(cc2ccccc12)-c1ccc2CC(Cc2c1)NS(=O)(=O)c1ccccc1
Show InChI InChI=1S/C25H22N2O4S/c1-31-25(28)27-23-10-6-5-7-18(23)16-24(27)19-12-11-17-14-21(15-20(17)13-19)26-32(29,30)22-8-3-2-4-9-22/h2-13,16,21,26H,14-15H2,1H3
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n/an/an/an/a>3.00E+4n/an/a7.522



Tanabe Research Laboratories USA



Assay Description
Polyhistidine-tagged human LXR ligand-binding domain was mixed with the test compound, biotin-SRC1 peptide, streptavidin-allophycocyanin, and europiu...

Bioorg Med Chem Lett 17: 3473-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.03.076
BindingDB Entry DOI: 10.7270/Q2HD7T00
More data for this
Ligand-Target Pair
Oxysterols receptor LXR-beta


(Homo sapiens (Human))		BDBM27291
PNG
(ethyl 2-(2-benzenesulfonamido-2,3-dihydro-1H-inden...)
Show SMILES CCOC(=O)n1c(cc2ccccc12)-c1ccc2CC(Cc2c1)NS(=O)(=O)c1ccccc1
Show InChI InChI=1S/C26H24N2O4S/c1-2-32-26(29)28-24-11-7-6-8-19(24)17-25(28)20-13-12-18-15-22(16-21(18)14-20)27-33(30,31)23-9-4-3-5-10-23/h3-14,17,22,27H,2,15-16H2,1H3
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n/an/an/an/a 1.60E+3n/an/a7.522



Tanabe Research Laboratories USA



Assay Description
Polyhistidine-tagged human LXR ligand-binding domain was mixed with the test compound, biotin-SRC1 peptide, streptavidin-allophycocyanin, and europiu...

Bioorg Med Chem Lett 17: 3473-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.03.076
BindingDB Entry DOI: 10.7270/Q2HD7T00
More data for this
Ligand-Target Pair
Oxysterols receptor LXR-beta


(Homo sapiens (Human))		BDBM27308
PNG
(indole derivative, 5c | tert-butyl 2-{2-[(4-ethylb...)
Show SMILES CCc1ccc(cc1)S(=O)(=O)NC1Cc2ccc(cc2C1)-c1cc2ccccc2n1C(=O)OC(C)(C)C
Show InChI InChI=1S/C30H32N2O4S/c1-5-20-10-14-26(15-11-20)37(34,35)31-25-17-21-12-13-23(16-24(21)18-25)28-19-22-8-6-7-9-27(22)32(28)29(33)36-30(2,3)4/h6-16,19,25,31H,5,17-18H2,1-4H3
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n/an/an/an/a 650n/an/an/an/a



Tanabe Research Laboratories USA



Assay Description
Polyhistidine-tagged human LXR ligand-binding domain was mixed with the test compound, biotin-SRC1 peptide, streptavidin-allophycocyanin, and europiu...

Bioorg Med Chem Lett 17: 3473-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.03.076
BindingDB Entry DOI: 10.7270/Q2HD7T00
More data for this
Ligand-Target Pair
Oxysterols receptor LXR-beta


(Homo sapiens (Human))		BDBM27310
PNG
(indole derivative, 5e | tert-butyl 2-(2-{[4-(trifl...)
Show SMILES CC(C)(C)OC(=O)n1c(cc2ccccc12)-c1ccc2CC(Cc2c1)NS(=O)(=O)c1ccc(cc1)C(F)(F)F
Show InChI InChI=1S/C29H27F3N2O4S/c1-28(2,3)38-27(35)34-25-7-5-4-6-19(25)17-26(34)20-9-8-18-15-23(16-21(18)14-20)33-39(36,37)24-12-10-22(11-13-24)29(30,31)32/h4-14,17,23,33H,15-16H2,1-3H3
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n/an/an/an/a 730n/an/an/an/a



Tanabe Research Laboratories USA



Assay Description
Polyhistidine-tagged human LXR ligand-binding domain was mixed with the test compound, biotin-SRC1 peptide, streptavidin-allophycocyanin, and europiu...

Bioorg Med Chem Lett 17: 3473-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.03.076
BindingDB Entry DOI: 10.7270/Q2HD7T00
More data for this
Ligand-Target Pair
Oxysterols receptor LXR-beta


(Homo sapiens (Human))		BDBM27314
PNG
(indole derivative, 5i | tert-butyl 2-{2-[(3-cyanob...)
Show SMILES CC(C)(C)OC(=O)n1c(cc2ccccc12)-c1ccc2CC(Cc2c1)NS(=O)(=O)c1cccc(c1)C#N
Show InChI InChI=1S/C29H27N3O4S/c1-29(2,3)36-28(33)32-26-10-5-4-8-21(26)17-27(32)22-12-11-20-15-24(16-23(20)14-22)31-37(34,35)25-9-6-7-19(13-25)18-30/h4-14,17,24,31H,15-16H2,1-3H3
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n/an/an/an/a 460n/an/an/an/a



Tanabe Research Laboratories USA



Assay Description
Polyhistidine-tagged human LXR ligand-binding domain was mixed with the test compound, biotin-SRC1 peptide, streptavidin-allophycocyanin, and europiu...

Bioorg Med Chem Lett 17: 3473-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.03.076
BindingDB Entry DOI: 10.7270/Q2HD7T00
More data for this
Ligand-Target Pair
Oxysterols receptor LXR-beta


(Homo sapiens (Human))		BDBM27318
PNG
(indole derivative, 5m | tert-butyl 2-{2-[(2-methox...)
Show SMILES COc1ccccc1S(=O)(=O)NC1Cc2ccc(cc2C1)-c1cc2ccccc2n1C(=O)OC(C)(C)C
Show InChI InChI=1S/C29H30N2O5S/c1-29(2,3)36-28(32)31-24-10-6-5-9-20(24)18-25(31)21-14-13-19-16-23(17-22(19)15-21)30-37(33,34)27-12-8-7-11-26(27)35-4/h5-15,18,23,30H,16-17H2,1-4H3
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n/an/an/an/a 600n/an/an/an/a



Tanabe Research Laboratories USA



Assay Description
Polyhistidine-tagged human LXR ligand-binding domain was mixed with the test compound, biotin-SRC1 peptide, streptavidin-allophycocyanin, and europiu...

Bioorg Med Chem Lett 17: 3473-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.03.076
BindingDB Entry DOI: 10.7270/Q2HD7T00
More data for this
Ligand-Target Pair
Oxysterols receptor LXR-beta


(Homo sapiens (Human))		BDBM27323
PNG
(indole derivative, 5r | tert-butyl 2-{2-[(2-chloro...)
Show SMILES CC(C)(C)OC(=O)n1c(cc2ccccc12)-c1ccc2CC(Cc2c1)NS(=O)(=O)c1ccccc1Cl
Show InChI InChI=1S/C28H27ClN2O4S/c1-28(2,3)35-27(32)31-24-10-6-4-8-19(24)17-25(31)20-13-12-18-15-22(16-21(18)14-20)30-36(33,34)26-11-7-5-9-23(26)29/h4-14,17,22,30H,15-16H2,1-3H3
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n/an/an/an/a 760n/an/an/an/a



Tanabe Research Laboratories USA



Assay Description
Polyhistidine-tagged human LXR ligand-binding domain was mixed with the test compound, biotin-SRC1 peptide, streptavidin-allophycocyanin, and europiu...

Bioorg Med Chem Lett 17: 3473-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.03.076
BindingDB Entry DOI: 10.7270/Q2HD7T00
More data for this
Ligand-Target Pair
Oxysterols receptor LXR-beta


(Homo sapiens (Human))		BDBM27330
PNG
(indole derivative, 5y | tert-butyl 2-(2-ethanesulf...)
Show SMILES CCS(=O)(=O)NC1Cc2ccc(cc2C1)-c1cc2ccccc2n1C(=O)OC(C)(C)C
Show InChI InChI=1S/C24H28N2O4S/c1-5-31(28,29)25-20-13-16-10-11-18(12-19(16)14-20)22-15-17-8-6-7-9-21(17)26(22)23(27)30-24(2,3)4/h6-12,15,20,25H,5,13-14H2,1-4H3
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n/an/an/an/a 400n/an/an/an/a



Tanabe Research Laboratories USA



Assay Description
Polyhistidine-tagged human LXR ligand-binding domain was mixed with the test compound, biotin-SRC1 peptide, streptavidin-allophycocyanin, and europiu...

Bioorg Med Chem Lett 17: 3473-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.03.076
BindingDB Entry DOI: 10.7270/Q2HD7T00
More data for this
Ligand-Target Pair
Oxysterols receptor LXR-beta


(Homo sapiens (Human))		BDBM27284
PNG
(indole derivative, 1j | tert-butyl 2-(2-benzenesul...)
Show SMILES COc1ccc2cc(-c3ccc4CC(Cc4c3)NS(=O)(=O)c3ccccc3)n(C(=O)OC(C)(C)C)c2c1
Show InChI InChI=1S/C29H30N2O5S/c1-29(2,3)36-28(32)31-26(17-21-12-13-24(35-4)18-27(21)31)20-11-10-19-15-23(16-22(19)14-20)30-37(33,34)25-8-6-5-7-9-25/h5-14,17-18,23,30H,15-16H2,1-4H3
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n/an/an/an/a 1.60E+3n/an/a7.522



Tanabe Research Laboratories USA



Assay Description
Polyhistidine-tagged human LXR ligand-binding domain was mixed with the test compound, biotin-SRC1 peptide, streptavidin-allophycocyanin, and europiu...

Bioorg Med Chem Lett 17: 3473-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.03.076
BindingDB Entry DOI: 10.7270/Q2HD7T00
More data for this
Ligand-Target Pair
Oxysterols receptor LXR-beta


(Homo sapiens (Human))		BDBM27286
PNG
(indole derivative, 1l | tert-butyl 2-(2-benzenesul...)
Show SMILES CC(C)(C)OC(=O)n1c(cc2ccc(O)cc12)-c1ccc2CC(Cc2c1)NS(=O)(=O)c1ccccc1
Show InChI InChI=1S/C28H28N2O5S/c1-28(2,3)35-27(32)30-25(16-20-11-12-23(31)17-26(20)30)19-10-9-18-14-22(15-21(18)13-19)29-36(33,34)24-7-5-4-6-8-24/h4-13,16-17,22,29,31H,14-15H2,1-3H3
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n/an/an/an/a 670n/an/a7.522



Tanabe Research Laboratories USA



Assay Description
Polyhistidine-tagged human LXR ligand-binding domain was mixed with the test compound, biotin-SRC1 peptide, streptavidin-allophycocyanin, and europiu...

Bioorg Med Chem Lett 17: 3473-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.03.076
BindingDB Entry DOI: 10.7270/Q2HD7T00
More data for this
Ligand-Target Pair
Oxysterols receptor LXR-beta


(Homo sapiens (Human))		BDBM27287
PNG
(indole derivative, 1m (R) | tert-butyl 2-[(2R)-2-b...)
Show SMILES CC(C)(C)OC(=O)n1c(cc2ccccc12)-c1ccc2C[C@H](Cc2c1)NS(=O)(=O)c1ccccc1 |r|
Show InChI InChI=1S/C28H28N2O4S/c1-28(2,3)34-27(31)30-25-12-8-7-9-20(25)18-26(30)21-14-13-19-16-23(17-22(19)15-21)29-35(32,33)24-10-5-4-6-11-24/h4-15,18,23,29H,16-17H2,1-3H3/t23-/m1/s1
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n/an/an/an/a 660n/an/a7.522



Tanabe Research Laboratories USA



Assay Description
Polyhistidine-tagged human LXR ligand-binding domain was mixed with the test compound, biotin-SRC1 peptide, streptavidin-allophycocyanin, and europiu...

Bioorg Med Chem Lett 17: 3473-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.03.076
BindingDB Entry DOI: 10.7270/Q2HD7T00
More data for this
Ligand-Target Pair
Oxysterols receptor LXR-beta


(Homo sapiens (Human))		BDBM27298
PNG
(N-[5-(1-hexanoyl-1H-indol-2-yl)-2,3-dihydro-1H-ind...)
Show SMILES CCCCCC(=O)n1c(cc2ccccc12)-c1ccc2CC(Cc2c1)NS(=O)(=O)c1ccccc1
Show InChI InChI=1S/C29H30N2O3S/c1-2-3-5-14-29(32)31-27-13-9-8-10-22(27)20-28(31)23-16-15-21-18-25(19-24(21)17-23)30-35(33,34)26-11-6-4-7-12-26/h4,6-13,15-17,20,25,30H,2-3,5,14,18-19H2,1H3
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n/an/an/an/a 2.10E+3n/an/a7.522



Tanabe Research Laboratories USA



Assay Description
Polyhistidine-tagged human LXR ligand-binding domain was mixed with the test compound, biotin-SRC1 peptide, streptavidin-allophycocyanin, and europiu...

Bioorg Med Chem Lett 17: 3473-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.03.076
BindingDB Entry DOI: 10.7270/Q2HD7T00
More data for this
Ligand-Target Pair
Oxysterols receptor LXR-beta


(Homo sapiens (Human))		BDBM27301
PNG
(indole derivative, 23 | tert-butyl 2-[2-(2-benzene...)
Show SMILES CC(C)(C)OC(=O)Cn1c(cc2ccccc12)-c1ccc2CC(Cc2c1)NS(=O)(=O)c1ccccc1
Show InChI InChI=1S/C29H30N2O4S/c1-29(2,3)35-28(32)19-31-26-12-8-7-9-21(26)18-27(31)22-14-13-20-16-24(17-23(20)15-22)30-36(33,34)25-10-5-4-6-11-25/h4-15,18,24,30H,16-17,19H2,1-3H3
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n/an/an/an/a>3.00E+4n/an/a7.522



Tanabe Research Laboratories USA



Assay Description
Polyhistidine-tagged human LXR ligand-binding domain was mixed with the test compound, biotin-SRC1 peptide, streptavidin-allophycocyanin, and europiu...

Bioorg Med Chem Lett 17: 3473-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.03.076
BindingDB Entry DOI: 10.7270/Q2HD7T00
More data for this
Ligand-Target Pair
Oxysterols receptor LXR-beta


(Homo sapiens (Human))		BDBM27307
PNG
(indole derivative, 5b | tert-butyl 2-{2-[(4-fluoro...)
Show SMILES CC(C)(C)OC(=O)n1c(cc2ccccc12)-c1ccc2CC(Cc2c1)NS(=O)(=O)c1ccc(F)cc1
Show InChI InChI=1S/C28H27FN2O4S/c1-28(2,3)35-27(32)31-25-7-5-4-6-19(25)17-26(31)20-9-8-18-15-23(16-21(18)14-20)30-36(33,34)24-12-10-22(29)11-13-24/h4-14,17,23,30H,15-16H2,1-3H3
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n/an/an/an/a 460n/an/an/an/a



Tanabe Research Laboratories USA



Assay Description
Polyhistidine-tagged human LXR ligand-binding domain was mixed with the test compound, biotin-SRC1 peptide, streptavidin-allophycocyanin, and europiu...

Bioorg Med Chem Lett 17: 3473-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.03.076
BindingDB Entry DOI: 10.7270/Q2HD7T00
More data for this
Ligand-Target Pair
Oxysterols receptor LXR-beta


(Homo sapiens (Human))		BDBM27325
PNG
(indole derivative, 5t | tert-butyl 2-(2-{[5-(1,2-o...)
Show SMILES CC(C)(C)OC(=O)n1c(cc2ccccc12)-c1ccc2CC(Cc2c1)NS(=O)(=O)c1ccc(s1)-c1ccon1
Show InChI InChI=1S/C29H27N3O5S2/c1-29(2,3)37-28(33)32-24-7-5-4-6-19(24)17-25(32)20-9-8-18-15-22(16-21(18)14-20)31-39(34,35)27-11-10-26(38-27)23-12-13-36-30-23/h4-14,17,22,31H,15-16H2,1-3H3
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n/an/an/an/a 670n/an/an/an/a



Tanabe Research Laboratories USA



Assay Description
Polyhistidine-tagged human LXR ligand-binding domain was mixed with the test compound, biotin-SRC1 peptide, streptavidin-allophycocyanin, and europiu...

Bioorg Med Chem Lett 17: 3473-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.03.076
BindingDB Entry DOI: 10.7270/Q2HD7T00
More data for this
Ligand-Target Pair
Oxysterols receptor LXR-beta


(Homo sapiens (Human))		BDBM27275
PNG
(indole derivative, 1a | tert-butyl 2-(2-benzenesul...)
Show SMILES CC(C)(C)OC(=O)n1c(cc2c(O)cccc12)-c1ccc2CC(Cc2c1)NS(=O)(=O)c1ccccc1
Show InChI InChI=1S/C28H28N2O5S/c1-28(2,3)35-27(32)30-24-10-7-11-26(31)23(24)17-25(30)19-13-12-18-15-21(16-20(18)14-19)29-36(33,34)22-8-5-4-6-9-22/h4-14,17,21,29,31H,15-16H2,1-3H3
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n/an/an/an/a>3.00E+4n/an/a7.522



Tanabe Research Laboratories USA



Assay Description
Polyhistidine-tagged human LXR ligand-binding domain was mixed with the test compound, biotin-SRC1 peptide, streptavidin-allophycocyanin, and europiu...

Bioorg Med Chem Lett 17: 3473-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.03.076
BindingDB Entry DOI: 10.7270/Q2HD7T00
More data for this
Ligand-Target Pair
Oxysterols receptor LXR-beta


(Homo sapiens (Human))		BDBM27283
PNG
(indole derivative, 1i | tert-butyl 2-(2-benzenesul...)
Show SMILES CC(C)(C)OC(=O)n1c(cc2ccc(OCc3ccccc3)cc12)-c1ccc2CC(Cc2c1)NS(=O)(=O)c1ccccc1
Show InChI InChI=1S/C35H34N2O5S/c1-35(2,3)42-34(38)37-32(21-27-16-17-30(22-33(27)37)41-23-24-10-6-4-7-11-24)26-15-14-25-19-29(20-28(25)18-26)36-43(39,40)31-12-8-5-9-13-31/h4-18,21-22,29,36H,19-20,23H2,1-3H3
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n/an/an/an/a>3.00E+4n/an/a7.522



Tanabe Research Laboratories USA



Assay Description
Polyhistidine-tagged human LXR ligand-binding domain was mixed with the test compound, biotin-SRC1 peptide, streptavidin-allophycocyanin, and europiu...

Bioorg Med Chem Lett 17: 3473-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.03.076
BindingDB Entry DOI: 10.7270/Q2HD7T00
More data for this
Ligand-Target Pair
Oxysterols receptor LXR-beta


(Homo sapiens (Human))		BDBM27297
PNG
(N-[5-(1-cyclopentanecarbonyl-1H-indol-2-yl)-2,3-di...)
Show SMILES O=C(C1CCCC1)n1c(cc2ccccc12)-c1ccc2CC(Cc2c1)NS(=O)(=O)c1ccccc1
Show InChI InChI=1S/C29H28N2O3S/c32-29(20-8-4-5-9-20)31-27-13-7-6-10-22(27)19-28(31)23-15-14-21-17-25(18-24(21)16-23)30-35(33,34)26-11-2-1-3-12-26/h1-3,6-7,10-16,19-20,25,30H,4-5,8-9,17-18H2
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n/an/an/an/a 900n/an/a7.522



Tanabe Research Laboratories USA



Assay Description
Polyhistidine-tagged human LXR ligand-binding domain was mixed with the test compound, biotin-SRC1 peptide, streptavidin-allophycocyanin, and europiu...

Bioorg Med Chem Lett 17: 3473-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.03.076
BindingDB Entry DOI: 10.7270/Q2HD7T00
More data for this
Ligand-Target Pair
Oxysterols receptor LXR-beta


(Homo sapiens (Human))		BDBM27299
PNG
(N-{5-[1-(3,3-dimethylbutanoyl)-1H-indol-2-yl]-2,3-...)
Show SMILES CC(C)(C)CC(=O)n1c(cc2ccccc12)-c1ccc2CC(Cc2c1)NS(=O)(=O)c1ccccc1
Show InChI InChI=1S/C29H30N2O3S/c1-29(2,3)19-28(32)31-26-12-8-7-9-21(26)18-27(31)22-14-13-20-16-24(17-23(20)15-22)30-35(33,34)25-10-5-4-6-11-25/h4-15,18,24,30H,16-17,19H2,1-3H3
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n/an/an/an/a>3.00E+4n/an/a7.522



Tanabe Research Laboratories USA



Assay Description
Polyhistidine-tagged human LXR ligand-binding domain was mixed with the test compound, biotin-SRC1 peptide, streptavidin-allophycocyanin, and europiu...

Bioorg Med Chem Lett 17: 3473-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.03.076
BindingDB Entry DOI: 10.7270/Q2HD7T00
More data for this
Ligand-Target Pair
Oxysterols receptor LXR-beta


(Homo sapiens (Human))		BDBM27300
PNG
(N-[5-(1-methyl-1H-indol-2-yl)-2,3-dihydro-1H-inden...)
Show SMILES Cn1c(cc2ccccc12)-c1ccc2CC(Cc2c1)NS(=O)(=O)c1ccccc1
Show InChI InChI=1S/C24H22N2O2S/c1-26-23-10-6-5-7-18(23)16-24(26)19-12-11-17-14-21(15-20(17)13-19)25-29(27,28)22-8-3-2-4-9-22/h2-13,16,21,25H,14-15H2,1H3
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n/an/an/an/a>3.00E+4n/an/a7.522



Tanabe Research Laboratories USA



Assay Description
Polyhistidine-tagged human LXR ligand-binding domain was mixed with the test compound, biotin-SRC1 peptide, streptavidin-allophycocyanin, and europiu...

Bioorg Med Chem Lett 17: 3473-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.03.076
BindingDB Entry DOI: 10.7270/Q2HD7T00
More data for this
Ligand-Target Pair
Oxysterols receptor LXR-beta


(Homo sapiens (Human))		BDBM27303
PNG
(N-[5-(1-benzyl-1H-indol-2-yl)-2,3-dihydro-1H-inden...)
Show SMILES O=S(=O)(NC1Cc2ccc(cc2C1)-c1cc2ccccc2n1Cc1ccccc1)c1ccccc1
Show InChI InChI=1S/C30H26N2O2S/c33-35(34,28-12-5-2-6-13-28)31-27-18-23-15-16-25(17-26(23)19-27)30-20-24-11-7-8-14-29(24)32(30)21-22-9-3-1-4-10-22/h1-17,20,27,31H,18-19,21H2
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n/an/an/an/a>3.00E+4n/an/a7.522



Tanabe Research Laboratories USA



Assay Description
Polyhistidine-tagged human LXR ligand-binding domain was mixed with the test compound, biotin-SRC1 peptide, streptavidin-allophycocyanin, and europiu...

Bioorg Med Chem Lett 17: 3473-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.03.076
BindingDB Entry DOI: 10.7270/Q2HD7T00
More data for this
Ligand-Target Pair
Oxysterols receptor LXR-beta


(Homo sapiens (Human))		BDBM27328
PNG
(indole derivative, 5w | tert-butyl 2-[2-(phenylmet...)
Show SMILES CC(C)(C)OC(=O)n1c(cc2ccccc12)-c1ccc2CC(Cc2c1)NS(=O)(=O)Cc1ccccc1
Show InChI InChI=1S/C29H30N2O4S/c1-29(2,3)35-28(32)31-26-12-8-7-11-22(26)18-27(31)23-14-13-21-16-25(17-24(21)15-23)30-36(33,34)19-20-9-5-4-6-10-20/h4-15,18,25,30H,16-17,19H2,1-3H3
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n/an/an/an/a 520n/an/an/an/a



Tanabe Research Laboratories USA



Assay Description
Polyhistidine-tagged human LXR ligand-binding domain was mixed with the test compound, biotin-SRC1 peptide, streptavidin-allophycocyanin, and europiu...

Bioorg Med Chem Lett 17: 3473-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.03.076
BindingDB Entry DOI: 10.7270/Q2HD7T00
More data for this
Ligand-Target Pair
Oxysterols receptor LXR-beta


(Homo sapiens (Human))		BDBM27292
PNG
(3-methylbutyl 2-(2-benzenesulfonamido-2,3-dihydro-...)
Show SMILES CC(C)CCOC(=O)n1c(cc2ccccc12)-c1ccc2CC(Cc2c1)NS(=O)(=O)c1ccccc1
Show InChI InChI=1S/C29H30N2O4S/c1-20(2)14-15-35-29(32)31-27-11-7-6-8-22(27)19-28(31)23-13-12-21-17-25(18-24(21)16-23)30-36(33,34)26-9-4-3-5-10-26/h3-13,16,19-20,25,30H,14-15,17-18H2,1-2H3
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n/an/an/an/a 1.30E+3n/an/a7.522



Tanabe Research Laboratories USA



Assay Description
Polyhistidine-tagged human LXR ligand-binding domain was mixed with the test compound, biotin-SRC1 peptide, streptavidin-allophycocyanin, and europiu...

Bioorg Med Chem Lett 17: 3473-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.03.076
BindingDB Entry DOI: 10.7270/Q2HD7T00
More data for this
Ligand-Target Pair
Oxysterols receptor LXR-beta


(Homo sapiens (Human))		BDBM27306
PNG
(indole derivative, 5a | tert-butyl 2-{2-[(4-chloro...)
Show SMILES CC(C)(C)OC(=O)n1c(cc2ccccc12)-c1ccc2CC(Cc2c1)NS(=O)(=O)c1ccc(Cl)cc1
Show InChI InChI=1S/C28H27ClN2O4S/c1-28(2,3)35-27(32)31-25-7-5-4-6-19(25)17-26(31)20-9-8-18-15-23(16-21(18)14-20)30-36(33,34)24-12-10-22(29)11-13-24/h4-14,17,23,30H,15-16H2,1-3H3
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n/an/an/an/a 1.16E+3n/an/an/an/a



Tanabe Research Laboratories USA



Assay Description
Polyhistidine-tagged human LXR ligand-binding domain was mixed with the test compound, biotin-SRC1 peptide, streptavidin-allophycocyanin, and europiu...

Bioorg Med Chem Lett 17: 3473-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.03.076
BindingDB Entry DOI: 10.7270/Q2HD7T00
More data for this
Ligand-Target Pair
Oxysterols receptor LXR-beta


(Homo sapiens (Human))		BDBM27312
PNG
(indole derivative, 5g | tert-butyl 2-{2-[(3-methyl...)
Show SMILES Cc1cccc(c1)S(=O)(=O)NC1Cc2ccc(cc2C1)-c1cc2ccccc2n1C(=O)OC(C)(C)C
Show InChI InChI=1S/C29H30N2O4S/c1-19-8-7-10-25(14-19)36(33,34)30-24-16-20-12-13-22(15-23(20)17-24)27-18-21-9-5-6-11-26(21)31(27)28(32)35-29(2,3)4/h5-15,18,24,30H,16-17H2,1-4H3
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n/an/an/an/a 1.33E+3n/an/an/an/a



Tanabe Research Laboratories USA



Assay Description
Polyhistidine-tagged human LXR ligand-binding domain was mixed with the test compound, biotin-SRC1 peptide, streptavidin-allophycocyanin, and europiu...

Bioorg Med Chem Lett 17: 3473-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.03.076
BindingDB Entry DOI: 10.7270/Q2HD7T00
More data for this
Ligand-Target Pair
Oxysterols receptor LXR-beta


(Homo sapiens (Human))		BDBM27313
PNG
(indole derivative, 5h | tert-butyl 2-{2-[(3-methox...)
Show SMILES COc1cccc(c1)S(=O)(=O)NC1Cc2ccc(cc2C1)-c1cc2ccccc2n1C(=O)OC(C)(C)C
Show InChI InChI=1S/C29H30N2O5S/c1-29(2,3)36-28(32)31-26-11-6-5-8-20(26)17-27(31)21-13-12-19-15-23(16-22(19)14-21)30-37(33,34)25-10-7-9-24(18-25)35-4/h5-14,17-18,23,30H,15-16H2,1-4H3
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n/an/an/an/a 960n/an/an/an/a



Tanabe Research Laboratories USA



Assay Description
Polyhistidine-tagged human LXR ligand-binding domain was mixed with the test compound, biotin-SRC1 peptide, streptavidin-allophycocyanin, and europiu...

Bioorg Med Chem Lett 17: 3473-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.03.076
BindingDB Entry DOI: 10.7270/Q2HD7T00
More data for this
Ligand-Target Pair
Oxysterols receptor LXR-alpha


(Homo sapiens (Human))		BDBM27325
PNG
(indole derivative, 5t | tert-butyl 2-(2-{[5-(1,2-o...)
Show SMILES CC(C)(C)OC(=O)n1c(cc2ccccc12)-c1ccc2CC(Cc2c1)NS(=O)(=O)c1ccc(s1)-c1ccon1
Show InChI InChI=1S/C29H27N3O5S2/c1-29(2,3)37-28(33)32-24-7-5-4-6-19(24)17-25(32)20-9-8-18-15-22(16-21(18)14-20)31-39(34,35)27-11-10-26(38-27)23-12-13-36-30-23/h4-14,17,22,31H,15-16H2,1-3H3
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n/an/an/an/a>3.00E+4n/an/an/an/a



Tanabe Research Laboratories USA



Assay Description
Polyhistidine-tagged human LXR ligand-binding domain was mixed with the test compound, biotin-SRC1 peptide, streptavidin-allophycocyanin, and europiu...

Bioorg Med Chem Lett 17: 3473-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.03.076
BindingDB Entry DOI: 10.7270/Q2HD7T00
More data for this
Ligand-Target Pair
Oxysterols receptor LXR-alpha


(Homo sapiens (Human))		BDBM23738
PNG
(2-(1-benzyl-5-methoxy-2-methyl-1H-indol-3-yl)aceta...)
Show SMILES COc1ccc2n(Cc3ccccc3)c(C)c(CC(N)=O)c2c1
Show InChI InChI=1S/C19H20N2O2/c1-13-16(11-19(20)22)17-10-15(23-2)8-9-18(17)21(13)12-14-6-4-3-5-7-14/h3-10H,11-12H2,1-2H3,(H2,20,22)
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n/an/an/an/a 1.50E+3n/an/an/an/a



Tanabe Research Laboratories USA



Assay Description
Polyhistidine-tagged human LXR ligand-binding domain was mixed with the test compound, biotin-SRC1 peptide, streptavidin-allophycocyanin, and europiu...

Bioorg Med Chem Lett 17: 3473-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.03.076
BindingDB Entry DOI: 10.7270/Q2HD7T00
More data for this
Ligand-Target Pair
Oxysterols receptor LXR-beta


(Homo sapiens (Human))		BDBM27332
PNG
(indole derivative, 38 | tert-butyl 2-{2-[(2-fluoro...)
Show SMILES CC(C)(C)OC(=O)n1c(cc2ccccc12)-c1ccc2CC(Cc2c1)NC(=O)c1ccccc1F
Show InChI InChI=1S/C29H27FN2O3/c1-29(2,3)35-28(34)32-25-11-7-4-8-19(25)17-26(32)20-13-12-18-15-22(16-21(18)14-20)31-27(33)23-9-5-6-10-24(23)30/h4-14,17,22H,15-16H2,1-3H3,(H,31,33)
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n/an/an/an/a 170n/an/an/an/a



Tanabe Research Laboratories USA



Assay Description
Polyhistidine-tagged human LXR ligand-binding domain was mixed with the test compound, biotin-SRC1 peptide, streptavidin-allophycocyanin, and europiu...

Bioorg Med Chem Lett 17: 3473-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.03.076
BindingDB Entry DOI: 10.7270/Q2HD7T00
More data for this
Ligand-Target Pair
Oxysterols receptor LXR-beta


(Homo sapiens (Human))		BDBM27333
PNG
(indole derivative, 39 | tert-butyl 2-{2-[(2-methox...)
Show SMILES COc1ccccc1C(=O)NC1Cc2ccc(cc2C1)-c1cc2ccccc2n1C(=O)OC(C)(C)C
Show InChI InChI=1S/C30H30N2O4/c1-30(2,3)36-29(34)32-25-11-7-5-9-20(25)18-26(32)21-14-13-19-16-23(17-22(19)15-21)31-28(33)24-10-6-8-12-27(24)35-4/h5-15,18,23H,16-17H2,1-4H3,(H,31,33)
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n/an/an/an/a 470n/an/an/an/a



Tanabe Research Laboratories USA



Assay Description
Polyhistidine-tagged human LXR ligand-binding domain was mixed with the test compound, biotin-SRC1 peptide, streptavidin-allophycocyanin, and europiu...

Bioorg Med Chem Lett 17: 3473-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.03.076
BindingDB Entry DOI: 10.7270/Q2HD7T00
More data for this
Ligand-Target Pair
Oxysterols receptor LXR-beta


(Homo sapiens (Human))		BDBM27277
PNG
(indole derivative, 1c | tert-butyl 2-(2-benzenesul...)
Show SMILES CC(C)(C)OC(=O)n1c(cc2cc(O)ccc12)-c1ccc2CC(Cc2c1)NS(=O)(=O)c1ccccc1
Show InChI InChI=1S/C28H28N2O5S/c1-28(2,3)35-27(32)30-25-12-11-23(31)16-21(25)17-26(30)19-10-9-18-14-22(15-20(18)13-19)29-36(33,34)24-7-5-4-6-8-24/h4-13,16-17,22,29,31H,14-15H2,1-3H3
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n/an/an/an/a>3.00E+4n/an/a7.522



Tanabe Research Laboratories USA



Assay Description
Polyhistidine-tagged human LXR ligand-binding domain was mixed with the test compound, biotin-SRC1 peptide, streptavidin-allophycocyanin, and europiu...

Bioorg Med Chem Lett 17: 3473-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.03.076
BindingDB Entry DOI: 10.7270/Q2HD7T00
More data for this
Ligand-Target Pair
Oxysterols receptor LXR-beta


(Homo sapiens (Human))		BDBM27279
PNG
(indole derivative, 1e | tert-butyl 2-(2-benzenesul...)
Show SMILES CC(C)(C)OC(=O)n1c(cc2cc(F)ccc12)-c1ccc2CC(Cc2c1)NS(=O)(=O)c1ccccc1
Show InChI InChI=1S/C28H27FN2O4S/c1-28(2,3)35-27(32)31-25-12-11-22(29)14-21(25)17-26(31)19-10-9-18-15-23(16-20(18)13-19)30-36(33,34)24-7-5-4-6-8-24/h4-14,17,23,30H,15-16H2,1-3H3
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n/an/an/an/a 1.50E+3n/an/a7.522



Tanabe Research Laboratories USA



Assay Description
Polyhistidine-tagged human LXR ligand-binding domain was mixed with the test compound, biotin-SRC1 peptide, streptavidin-allophycocyanin, and europiu...

Bioorg Med Chem Lett 17: 3473-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.03.076
BindingDB Entry DOI: 10.7270/Q2HD7T00
More data for this
Ligand-Target Pair
Oxysterols receptor LXR-beta


(Homo sapiens (Human))		BDBM27282
PNG
(indole derivative, 1h | tert-butyl 2-(2-benzenesul...)
Show SMILES Cc1ccc2n(C(=O)OC(C)(C)C)c(cc2c1)-c1ccc2CC(Cc2c1)NS(=O)(=O)c1ccccc1
Show InChI InChI=1S/C29H30N2O4S/c1-19-10-13-26-23(14-19)18-27(31(26)28(32)35-29(2,3)4)21-12-11-20-16-24(17-22(20)15-21)30-36(33,34)25-8-6-5-7-9-25/h5-15,18,24,30H,16-17H2,1-4H3
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n/an/an/an/a 1.80E+4n/an/a7.522



Tanabe Research Laboratories USA



Assay Description
Polyhistidine-tagged human LXR ligand-binding domain was mixed with the test compound, biotin-SRC1 peptide, streptavidin-allophycocyanin, and europiu...

Bioorg Med Chem Lett 17: 3473-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.03.076
BindingDB Entry DOI: 10.7270/Q2HD7T00
More data for this
Ligand-Target Pair
Oxysterols receptor LXR-beta


(Homo sapiens (Human))		BDBM27293
PNG
(2,2-dimethylpropyl 2-(2-benzenesulfonamido-2,3-dih...)
Show SMILES CC(C)(C)COC(=O)n1c(cc2ccccc12)-c1ccc2CC(Cc2c1)NS(=O)(=O)c1ccccc1
Show InChI InChI=1S/C29H30N2O4S/c1-29(2,3)19-35-28(32)31-26-12-8-7-9-21(26)18-27(31)22-14-13-20-16-24(17-23(20)15-22)30-36(33,34)25-10-5-4-6-11-25/h4-15,18,24,30H,16-17,19H2,1-3H3
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n/an/an/an/a 1.40E+3n/an/a7.522



Tanabe Research Laboratories USA



Assay Description
Polyhistidine-tagged human LXR ligand-binding domain was mixed with the test compound, biotin-SRC1 peptide, streptavidin-allophycocyanin, and europiu...

Bioorg Med Chem Lett 17: 3473-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.03.076
BindingDB Entry DOI: 10.7270/Q2HD7T00
More data for this
Ligand-Target Pair
Oxysterols receptor LXR-beta


(Homo sapiens (Human))		BDBM27294
PNG
(2-methylhexyl 2-(2-benzenesulfonamido-2,3-dihydro-...)
Show SMILES CCCCC(C)COC(=O)n1c(cc2ccccc12)-c1ccc2CC(Cc2c1)NS(=O)(=O)c1ccccc1
Show InChI InChI=1S/C31H34N2O4S/c1-3-4-10-22(2)21-37-31(34)33-29-14-9-8-11-24(29)20-30(33)25-16-15-23-18-27(19-26(23)17-25)32-38(35,36)28-12-6-5-7-13-28/h5-9,11-17,20,22,27,32H,3-4,10,18-19,21H2,1-2H3
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n/an/an/an/a>3.00E+4n/an/a7.522



Tanabe Research Laboratories USA



Assay Description
Polyhistidine-tagged human LXR ligand-binding domain was mixed with the test compound, biotin-SRC1 peptide, streptavidin-allophycocyanin, and europiu...

Bioorg Med Chem Lett 17: 3473-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.03.076
BindingDB Entry DOI: 10.7270/Q2HD7T00
More data for this
Ligand-Target Pair
Oxysterols receptor LXR-beta


(Homo sapiens (Human))		BDBM27295
PNG
(N-{5-[1-(benzenesulfonyl)-1H-indol-2-yl]-2,3-dihyd...)
Show SMILES O=S(=O)(NC1Cc2ccc(cc2C1)-c1cc2ccccc2n1S(=O)(=O)c1ccccc1)c1ccccc1
Show InChI InChI=1S/C29H24N2O4S2/c32-36(33,26-10-3-1-4-11-26)30-25-18-21-15-16-23(17-24(21)19-25)29-20-22-9-7-8-14-28(22)31(29)37(34,35)27-12-5-2-6-13-27/h1-17,20,25,30H,18-19H2
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n/an/an/an/a>3.00E+4n/an/a7.522



Tanabe Research Laboratories USA



Assay Description
Polyhistidine-tagged human LXR ligand-binding domain was mixed with the test compound, biotin-SRC1 peptide, streptavidin-allophycocyanin, and europiu...

Bioorg Med Chem Lett 17: 3473-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.03.076
BindingDB Entry DOI: 10.7270/Q2HD7T00
More data for this
Ligand-Target Pair
Oxysterols receptor LXR-beta


(Homo sapiens (Human))		BDBM27305
PNG
(N-{5-[1-(2-phenylethyl)-1H-indol-2-yl]-2,3-dihydro...)
Show SMILES O=S(=O)(NC1Cc2ccc(cc2C1)-c1cc2ccccc2n1CCc1ccccc1)c1ccccc1
Show InChI InChI=1S/C31H28N2O2S/c34-36(35,29-12-5-2-6-13-29)32-28-20-24-15-16-26(19-27(24)21-28)31-22-25-11-7-8-14-30(25)33(31)18-17-23-9-3-1-4-10-23/h1-16,19,22,28,32H,17-18,20-21H2
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n/an/an/an/a>1.00E+4n/an/an/an/a



Tanabe Research Laboratories USA



Assay Description
Polyhistidine-tagged human LXR ligand-binding domain was mixed with the test compound, biotin-SRC1 peptide, streptavidin-allophycocyanin, and europiu...

Bioorg Med Chem Lett 17: 3473-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.03.076
BindingDB Entry DOI: 10.7270/Q2HD7T00
More data for this
Ligand-Target Pair
Oxysterols receptor LXR-beta


(Homo sapiens (Human))		BDBM27309
PNG
(indole derivative, 5d | tert-butyl 2-{2-[(4-methyl...)
Show SMILES Cc1ccc(cc1)S(=O)(=O)NC1Cc2ccc(cc2C1)-c1cc2ccccc2n1C(=O)OC(C)(C)C
Show InChI InChI=1S/C29H30N2O4S/c1-19-9-13-25(14-10-19)36(33,34)30-24-16-20-11-12-22(15-23(20)17-24)27-18-21-7-5-6-8-26(21)31(27)28(32)35-29(2,3)4/h5-15,18,24,30H,16-17H2,1-4H3
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n/an/an/an/a 430n/an/an/an/a



Tanabe Research Laboratories USA



Assay Description
Polyhistidine-tagged human LXR ligand-binding domain was mixed with the test compound, biotin-SRC1 peptide, streptavidin-allophycocyanin, and europiu...

Bioorg Med Chem Lett 17: 3473-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.03.076
BindingDB Entry DOI: 10.7270/Q2HD7T00
More data for this
Ligand-Target Pair
Oxysterols receptor LXR-beta


(Homo sapiens (Human))		BDBM27311
PNG
(indole derivative, 5f | tert-butyl 2-{2-[(3-chloro...)
Show SMILES CC(C)(C)OC(=O)n1c(cc2ccccc12)-c1ccc2CC(Cc2c1)NS(=O)(=O)c1cccc(Cl)c1
Show InChI InChI=1S/C28H27ClN2O4S/c1-28(2,3)35-27(32)31-25-10-5-4-7-19(25)16-26(31)20-12-11-18-14-23(15-21(18)13-20)30-36(33,34)24-9-6-8-22(29)17-24/h4-13,16-17,23,30H,14-15H2,1-3H3
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n/an/an/an/a 1.81E+3n/an/an/an/a



Tanabe Research Laboratories USA



Assay Description
Polyhistidine-tagged human LXR ligand-binding domain was mixed with the test compound, biotin-SRC1 peptide, streptavidin-allophycocyanin, and europiu...

Bioorg Med Chem Lett 17: 3473-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.03.076
BindingDB Entry DOI: 10.7270/Q2HD7T00
More data for this
Ligand-Target Pair
Oxysterols receptor LXR-beta


(Homo sapiens (Human))		BDBM27316
PNG
(2-[(5-{1-[(tert-butoxy)carbonyl]-1H-indol-2-yl}-2,...)
Show SMILES CC(C)(C)OC(=O)n1c(cc2ccccc12)-c1ccc2CC(Cc2c1)NS(=O)(=O)c1ccccc1C(O)=O
Show InChI InChI=1S/C29H28N2O6S/c1-29(2,3)37-28(34)31-24-10-6-4-8-19(24)17-25(31)20-13-12-18-15-22(16-21(18)14-20)30-38(35,36)26-11-7-5-9-23(26)27(32)33/h4-14,17,22,30H,15-16H2,1-3H3,(H,32,33)
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n/an/an/an/a 3.35E+3n/an/an/an/a



Tanabe Research Laboratories USA



Assay Description
Polyhistidine-tagged human LXR ligand-binding domain was mixed with the test compound, biotin-SRC1 peptide, streptavidin-allophycocyanin, and europiu...

Bioorg Med Chem Lett 17: 3473-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.03.076
BindingDB Entry DOI: 10.7270/Q2HD7T00
More data for this
Ligand-Target Pair
Oxysterols receptor LXR-beta


(Homo sapiens (Human))		BDBM27317
PNG
(indole derivative, 5l | tert-butyl 2-{2-[(2-methyl...)
Show SMILES Cc1ccccc1S(=O)(=O)NC1Cc2ccc(cc2C1)-c1cc2ccccc2n1C(=O)OC(C)(C)C
Show InChI InChI=1S/C29H30N2O4S/c1-19-9-5-8-12-27(19)36(33,34)30-24-16-20-13-14-22(15-23(20)17-24)26-18-21-10-6-7-11-25(21)31(26)28(32)35-29(2,3)4/h5-15,18,24,30H,16-17H2,1-4H3
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n/an/an/an/a 200n/an/an/an/a



Tanabe Research Laboratories USA



Assay Description
Polyhistidine-tagged human LXR ligand-binding domain was mixed with the test compound, biotin-SRC1 peptide, streptavidin-allophycocyanin, and europiu...

Bioorg Med Chem Lett 17: 3473-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.03.076
BindingDB Entry DOI: 10.7270/Q2HD7T00
More data for this
Ligand-Target Pair
Oxysterols receptor LXR-beta


(Homo sapiens (Human))		BDBM27322
PNG
(indole derivative, 5q | tert-butyl 2-{2-[(2,6-difl...)
Show SMILES CC(C)(C)OC(=O)n1c(cc2ccccc12)-c1ccc2CC(Cc2c1)NS(=O)(=O)c1c(F)cccc1F
Show InChI InChI=1S/C28H26F2N2O4S/c1-28(2,3)36-27(33)32-24-10-5-4-7-18(24)16-25(32)19-12-11-17-14-21(15-20(17)13-19)31-37(34,35)26-22(29)8-6-9-23(26)30/h4-13,16,21,31H,14-15H2,1-3H3
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n/an/an/an/a 90n/an/an/an/a



Tanabe Research Laboratories USA



Assay Description
Polyhistidine-tagged human LXR ligand-binding domain was mixed with the test compound, biotin-SRC1 peptide, streptavidin-allophycocyanin, and europiu...

Bioorg Med Chem Lett 17: 3473-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.03.076
BindingDB Entry DOI: 10.7270/Q2HD7T00
More data for this
Ligand-Target Pair
Oxysterols receptor LXR-beta


(Homo sapiens (Human))		BDBM27326
PNG
(indole derivative, 5u | tert-butyl 2-{2-[(3,5-dime...)
Show SMILES Cc1noc(C)c1S(=O)(=O)NC1Cc2ccc(cc2C1)-c1cc2ccccc2n1C(=O)OC(C)(C)C
Show InChI InChI=1S/C27H29N3O5S/c1-16-25(17(2)35-28-16)36(32,33)29-22-13-18-10-11-20(12-21(18)14-22)24-15-19-8-6-7-9-23(19)30(24)26(31)34-27(3,4)5/h6-12,15,22,29H,13-14H2,1-5H3
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n/an/an/an/a 130n/an/an/an/a



Tanabe Research Laboratories USA



Assay Description
Polyhistidine-tagged human LXR ligand-binding domain was mixed with the test compound, biotin-SRC1 peptide, streptavidin-allophycocyanin, and europiu...

Bioorg Med Chem Lett 17: 3473-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.03.076
BindingDB Entry DOI: 10.7270/Q2HD7T00
More data for this
Ligand-Target Pair
Oxysterols receptor LXR-beta


(Homo sapiens (Human))		BDBM27251
PNG
(indan derivative, 1 | tert-butyl 2-(2-benzenesulfo...)
Show SMILES CC(C)(C)OC(=O)n1c(cc2ccccc12)-c1ccc2CC(Cc2c1)NS(=O)(=O)c1ccccc1
Show InChI InChI=1S/C28H28N2O4S/c1-28(2,3)34-27(31)30-25-12-8-7-9-20(25)18-26(30)21-14-13-19-16-23(17-22(19)15-21)29-35(32,33)24-10-5-4-6-11-24/h4-15,18,23,29H,16-17H2,1-3H3
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n/an/an/an/a 210n/an/a7.522



Tanabe Research Laboratories USA



Assay Description
Polyhistidine-tagged human LXR ligand-binding domain was mixed with the test compound, biotin-SRC1 peptide, streptavidin-allophycocyanin, and europiu...

Bioorg Med Chem Lett 17: 3473-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.03.076
BindingDB Entry DOI: 10.7270/Q2HD7T00
More data for this
Ligand-Target Pair
Oxysterols receptor LXR-beta


(Homo sapiens (Human))		BDBM27276
PNG
(indole derivative, 1b | tert-butyl 2-(2-benzenesul...)
Show SMILES CC(C)(C)OC(=O)n1c(cc2c(OCc3ccccc3)cccc12)-c1ccc2CC(Cc2c1)NS(=O)(=O)c1ccccc1
Show InChI InChI=1S/C35H34N2O5S/c1-35(2,3)42-34(38)37-31-15-10-16-33(41-23-24-11-6-4-7-12-24)30(31)22-32(37)26-18-17-25-20-28(21-27(25)19-26)36-43(39,40)29-13-8-5-9-14-29/h4-19,22,28,36H,20-21,23H2,1-3H3
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n/an/an/an/a>3.00E+4n/an/a7.522



Tanabe Research Laboratories USA



Assay Description
Polyhistidine-tagged human LXR ligand-binding domain was mixed with the test compound, biotin-SRC1 peptide, streptavidin-allophycocyanin, and europiu...

Bioorg Med Chem Lett 17: 3473-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.03.076
BindingDB Entry DOI: 10.7270/Q2HD7T00
More data for this
Ligand-Target Pair
Oxysterols receptor LXR-beta


(Homo sapiens (Human))		BDBM27281
PNG
(indole derivative, 1g | tert-butyl 2-(2-benzenesul...)
Show SMILES COc1ccc2n(C(=O)OC(C)(C)C)c(cc2c1)-c1ccc2CC(Cc2c1)NS(=O)(=O)c1ccccc1
Show InChI InChI=1S/C29H30N2O5S/c1-29(2,3)36-28(32)31-26-13-12-24(35-4)17-22(26)18-27(31)20-11-10-19-15-23(16-21(19)14-20)30-37(33,34)25-8-6-5-7-9-25/h5-14,17-18,23,30H,15-16H2,1-4H3
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n/an/an/an/a 2.80E+4n/an/a7.522



Tanabe Research Laboratories USA



Assay Description
Polyhistidine-tagged human LXR ligand-binding domain was mixed with the test compound, biotin-SRC1 peptide, streptavidin-allophycocyanin, and europiu...

Bioorg Med Chem Lett 17: 3473-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.03.076
BindingDB Entry DOI: 10.7270/Q2HD7T00
More data for this
Ligand-Target Pair
Oxysterols receptor LXR-beta


(Homo sapiens (Human))		BDBM27289
PNG
(N-[5-(1H-indol-2-yl)-2,3-dihydro-1H-inden-2-yl]ben...)
Show SMILES O=S(=O)(NC1Cc2ccc(cc2C1)-c1cc2ccccc2[nH]1)c1ccccc1
Show InChI InChI=1S/C23H20N2O2S/c26-28(27,21-7-2-1-3-8-21)25-20-13-16-10-11-18(12-19(16)14-20)23-15-17-6-4-5-9-22(17)24-23/h1-12,15,20,24-25H,13-14H2
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n/an/an/an/a>3.00E+4n/an/a7.522



Tanabe Research Laboratories USA



Assay Description
Polyhistidine-tagged human LXR ligand-binding domain was mixed with the test compound, biotin-SRC1 peptide, streptavidin-allophycocyanin, and europiu...

Bioorg Med Chem Lett 17: 3473-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.03.076
BindingDB Entry DOI: 10.7270/Q2HD7T00
More data for this
Ligand-Target Pair
Oxysterols receptor LXR-beta


(Homo sapiens (Human))		BDBM27319
PNG
(indole derivative, 5n | tert-butyl 2-(2-{[2-(trifl...)
Show SMILES CC(C)(C)OC(=O)n1c(cc2ccccc12)-c1ccc2CC(Cc2c1)NS(=O)(=O)c1ccccc1C(F)(F)F
Show InChI InChI=1S/C29H27F3N2O4S/c1-28(2,3)38-27(35)34-24-10-6-4-8-19(24)17-25(34)20-13-12-18-15-22(16-21(18)14-20)33-39(36,37)26-11-7-5-9-23(26)29(30,31)32/h4-14,17,22,33H,15-16H2,1-3H3
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n/an/an/an/a 800n/an/an/an/a



Tanabe Research Laboratories USA



Assay Description
Polyhistidine-tagged human LXR ligand-binding domain was mixed with the test compound, biotin-SRC1 peptide, streptavidin-allophycocyanin, and europiu...

Bioorg Med Chem Lett 17: 3473-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.03.076
BindingDB Entry DOI: 10.7270/Q2HD7T00
More data for this
Ligand-Target Pair
Oxysterols receptor LXR-beta


(Homo sapiens (Human))		BDBM27324
PNG
(indole derivative, 5s | tert-butyl 2-[2-(thiophene...)
Show SMILES CC(C)(C)OC(=O)n1c(cc2ccccc12)-c1ccc2CC(Cc2c1)NS(=O)(=O)c1cccs1
Show InChI InChI=1S/C26H26N2O4S2/c1-26(2,3)32-25(29)28-22-8-5-4-7-18(22)16-23(28)19-11-10-17-14-21(15-20(17)13-19)27-34(30,31)24-9-6-12-33-24/h4-13,16,21,27H,14-15H2,1-3H3
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n/an/an/an/a 110n/an/an/an/a



Tanabe Research Laboratories USA



Assay Description
Polyhistidine-tagged human LXR ligand-binding domain was mixed with the test compound, biotin-SRC1 peptide, streptavidin-allophycocyanin, and europiu...

Bioorg Med Chem Lett 17: 3473-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.03.076
BindingDB Entry DOI: 10.7270/Q2HD7T00
More data for this
Ligand-Target Pair
Oxysterols receptor LXR-beta


(Homo sapiens (Human))		BDBM27329
PNG
(indole derivative, 5x | tert-butyl 2-(2-methanesul...)
Show SMILES CC(C)(C)OC(=O)n1c(cc2ccccc12)-c1ccc2CC(Cc2c1)NS(C)(=O)=O
Show InChI InChI=1S/C23H26N2O4S/c1-23(2,3)29-22(26)25-20-8-6-5-7-16(20)14-21(25)17-10-9-15-12-19(13-18(15)11-17)24-30(4,27)28/h5-11,14,19,24H,12-13H2,1-4H3
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n/an/an/an/a 210n/an/an/an/a



Tanabe Research Laboratories USA



Assay Description
Polyhistidine-tagged human LXR ligand-binding domain was mixed with the test compound, biotin-SRC1 peptide, streptavidin-allophycocyanin, and europiu...

Bioorg Med Chem Lett 17: 3473-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.03.076
BindingDB Entry DOI: 10.7270/Q2HD7T00
More data for this
Ligand-Target Pair
Oxysterols receptor LXR-beta


(Homo sapiens (Human))		BDBM27331
PNG
(indole derivative, 37 | tert-butyl 2-(2-benzamido-...)
Show SMILES CC(C)(C)OC(=O)n1c(cc2ccccc12)-c1ccc2CC(Cc2c1)NC(=O)c1ccccc1
Show InChI InChI=1S/C29H28N2O3/c1-29(2,3)34-28(33)31-25-12-8-7-11-21(25)18-26(31)22-14-13-20-16-24(17-23(20)15-22)30-27(32)19-9-5-4-6-10-19/h4-15,18,24H,16-17H2,1-3H3,(H,30,32)
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n/an/an/an/a 190n/an/an/an/a



Tanabe Research Laboratories USA



Assay Description
Polyhistidine-tagged human LXR ligand-binding domain was mixed with the test compound, biotin-SRC1 peptide, streptavidin-allophycocyanin, and europiu...

Bioorg Med Chem Lett 17: 3473-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.03.076
BindingDB Entry DOI: 10.7270/Q2HD7T00
More data for this
Ligand-Target Pair
Oxysterols receptor LXR-beta


(Homo sapiens (Human))		BDBM27335
PNG
(indole derivative, 41 | tert-butyl 2-{2-[(phenylca...)
Show SMILES CC(C)(C)OC(=O)n1c(cc2ccccc12)-c1ccc2CC(Cc2c1)NC(=O)Nc1ccccc1
Show InChI InChI=1S/C29H29N3O3/c1-29(2,3)35-28(34)32-25-12-8-7-9-20(25)18-26(32)21-14-13-19-16-24(17-22(19)15-21)31-27(33)30-23-10-5-4-6-11-23/h4-15,18,24H,16-17H2,1-3H3,(H2,30,31,33)
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n/an/an/an/a 1.50E+3n/an/an/an/a



Tanabe Research Laboratories USA



Assay Description
Polyhistidine-tagged human LXR ligand-binding domain was mixed with the test compound, biotin-SRC1 peptide, streptavidin-allophycocyanin, and europiu...

Bioorg Med Chem Lett 17: 3473-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.03.076
BindingDB Entry DOI: 10.7270/Q2HD7T00
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%