Found 13 hits of Enzyme Inhibition Constant Data Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Death-associated protein kinase 3
(Homo sapiens (Human)) | BDBM50314672
(2-(3-bromophenyl)-4-(pyridin-3-ylmethylene)oxazol-...)Show SMILES Brc1cccc(c1)C1=N\C(=C/c2cccnc2)C(=O)O1 |t:8| Show InChI InChI=1S/C15H9BrN2O2/c16-12-5-1-4-11(8-12)14-18-13(15(19)20-14)7-10-3-2-6-17-9-10/h1-9H/b13-7- | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 148 | n/a | n/a | n/a | n/a | n/a | n/a |
PharmaDesign, Inc.
Curated by ChEMBL
| Assay Description Inhibition of human recombinant DAPK3 |
Bioorg Med Chem 18: 2728-34 (2010)
Article DOI: 10.1016/j.bmc.2010.02.018 BindingDB Entry DOI: 10.7270/Q2RB74R2 |
More data for this Ligand-Target Pair | |
Death-associated protein kinase 3
(Homo sapiens (Human)) | BDBM50314673
(2-(2-bromo-4-methoxyphenyl)-4-(pyridin-3-ylmethyle...)Show SMILES COc1ccc(C2=N\C(=C/c3cccnc3)C(=O)O2)c(Br)c1 |t:6| Show InChI InChI=1S/C16H11BrN2O3/c1-21-11-4-5-12(13(17)8-11)15-19-14(16(20)22-15)7-10-3-2-6-18-9-10/h2-9H,1H3/b14-7- | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 157 | n/a | n/a | n/a | n/a | n/a | n/a |
PharmaDesign, Inc.
Curated by ChEMBL
| Assay Description Inhibition of human recombinant DAPK3 |
Bioorg Med Chem 18: 2728-34 (2010)
Article DOI: 10.1016/j.bmc.2010.02.018 BindingDB Entry DOI: 10.7270/Q2RB74R2 |
More data for this Ligand-Target Pair | |
Death-associated protein kinase 3
(Homo sapiens (Human)) | BDBM50314664
(2-(2-chloro-5-iodophenyl)-4-(pyridin-4-ylmethylene...)Show SMILES Clc1ccc(I)cc1C1=N\C(=C/c2ccncc2)C(=O)O1 |t:9| Show InChI InChI=1S/C15H8ClIN2O2/c16-12-2-1-10(17)8-11(12)14-19-13(15(20)21-14)7-9-3-5-18-6-4-9/h1-8H/b13-7- | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 227 | n/a | n/a | n/a | n/a | n/a | n/a |
PharmaDesign, Inc.
Curated by ChEMBL
| Assay Description Inhibition of human recombinant DAPK3 |
Bioorg Med Chem 18: 2728-34 (2010)
Article DOI: 10.1016/j.bmc.2010.02.018 BindingDB Entry DOI: 10.7270/Q2RB74R2 |
More data for this Ligand-Target Pair | |
Death-associated protein kinase 3
(Homo sapiens (Human)) | BDBM50314670
(2-(4-bromo-3-methylphenyl)-4-(pyridin-3-ylmethylen...)Show SMILES Cc1cc(ccc1Br)C1=N\C(=C/c2cccnc2)C(=O)O1 |t:9| Show InChI InChI=1S/C16H11BrN2O2/c1-10-7-12(4-5-13(10)17)15-19-14(16(20)21-15)8-11-3-2-6-18-9-11/h2-9H,1H3/b14-8- | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 279 | n/a | n/a | n/a | n/a | n/a | n/a |
PharmaDesign, Inc.
Curated by ChEMBL
| Assay Description Inhibition of human recombinant DAPK3 |
Bioorg Med Chem 18: 2728-34 (2010)
Article DOI: 10.1016/j.bmc.2010.02.018 BindingDB Entry DOI: 10.7270/Q2RB74R2 |
More data for this Ligand-Target Pair | |
Death-associated protein kinase 3
(Homo sapiens (Human)) | BDBM50314665
(2-(4-chloro-3-nitrophenyl)-4-(pyridin-3-ylmethylen...)Show SMILES [O-][N+](=O)c1cc(ccc1Cl)C1=N\C(=C/c2cccnc2)C(=O)O1 |t:11| Show InChI InChI=1S/C15H8ClN3O4/c16-11-4-3-10(7-13(11)19(21)22)14-18-12(15(20)23-14)6-9-2-1-5-17-8-9/h1-8H/b12-6- | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 279 | n/a | n/a | n/a | n/a | n/a | n/a |
PharmaDesign, Inc.
Curated by ChEMBL
| Assay Description Inhibition of human recombinant DAPK3 |
Bioorg Med Chem 18: 2728-34 (2010)
Article DOI: 10.1016/j.bmc.2010.02.018 BindingDB Entry DOI: 10.7270/Q2RB74R2 |
More data for this Ligand-Target Pair | |
Death-associated protein kinase 3
(Homo sapiens (Human)) | BDBM50314671
(2-(4-nitrophenyl)-4-(pyridin-3-ylmethylene)oxazol-...)Show SMILES [O-][N+](=O)c1ccc(cc1)C1=N\C(=C/c2cccnc2)C(=O)O1 |t:10| Show InChI InChI=1S/C15H9N3O4/c19-15-13(8-10-2-1-7-16-9-10)17-14(22-15)11-3-5-12(6-4-11)18(20)21/h1-9H/b13-8- | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 291 | n/a | n/a | n/a | n/a | n/a | n/a |
PharmaDesign, Inc.
Curated by ChEMBL
| Assay Description Inhibition of human recombinant DAPK3 |
Bioorg Med Chem 18: 2728-34 (2010)
Article DOI: 10.1016/j.bmc.2010.02.018 BindingDB Entry DOI: 10.7270/Q2RB74R2 |
More data for this Ligand-Target Pair | |
Death-associated protein kinase 3
(Homo sapiens (Human)) | BDBM50314668
(2-(3,4-difluorophenyl)-4-(pyridin-3-ylmethylene)ox...)Show SMILES Fc1ccc(cc1F)C1=N\C(=C/c2cccnc2)C(=O)O1 |t:9| Show InChI InChI=1S/C15H8F2N2O2/c16-11-4-3-10(7-12(11)17)14-19-13(15(20)21-14)6-9-2-1-5-18-8-9/h1-8H/b13-6- | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 346 | n/a | n/a | n/a | n/a | n/a | n/a |
PharmaDesign, Inc.
Curated by ChEMBL
| Assay Description Inhibition of human recombinant DAPK3 |
Bioorg Med Chem 18: 2728-34 (2010)
Article DOI: 10.1016/j.bmc.2010.02.018 BindingDB Entry DOI: 10.7270/Q2RB74R2 |
More data for this Ligand-Target Pair | |
Death-associated protein kinase 3
(Homo sapiens (Human)) | BDBM50314669
(2-(3-chlorophenyl)-4-(pyridin-3-ylmethylene)oxazol...)Show SMILES Clc1cccc(c1)C1=N\C(=C/c2cccnc2)C(=O)O1 |t:8| Show InChI InChI=1S/C15H9ClN2O2/c16-12-5-1-4-11(8-12)14-18-13(15(19)20-14)7-10-3-2-6-17-9-10/h1-9H/b13-7- | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 360 | n/a | n/a | n/a | n/a | n/a | n/a |
PharmaDesign, Inc.
Curated by ChEMBL
| Assay Description Inhibition of human recombinant DAPK3 |
Bioorg Med Chem 18: 2728-34 (2010)
Article DOI: 10.1016/j.bmc.2010.02.018 BindingDB Entry DOI: 10.7270/Q2RB74R2 |
More data for this Ligand-Target Pair | |
Death-associated protein kinase 3
(Homo sapiens (Human)) | BDBM50314674
(2-(3-methoxyphenyl)-4-(pyridin-3-ylmethylene)oxazo...)Show SMILES COc1cccc(c1)C1=N\C(=C/c2cccnc2)C(=O)O1 |t:9| Show InChI InChI=1S/C16H12N2O3/c1-20-13-6-2-5-12(9-13)15-18-14(16(19)21-15)8-11-4-3-7-17-10-11/h2-10H,1H3/b14-8- | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 395 | n/a | n/a | n/a | n/a | n/a | n/a |
PharmaDesign, Inc.
Curated by ChEMBL
| Assay Description Inhibition of human recombinant DAPK3 |
Bioorg Med Chem 18: 2728-34 (2010)
Article DOI: 10.1016/j.bmc.2010.02.018 BindingDB Entry DOI: 10.7270/Q2RB74R2 |
More data for this Ligand-Target Pair | |
Death-associated protein kinase 3
(Homo sapiens (Human)) | BDBM50314667
(2-(4-chlorophenyl)-4-(pyridin-3-ylmethylene)oxazol...)Show SMILES Clc1ccc(cc1)C1=N\C(=C/c2cccnc2)C(=O)O1 |t:8| Show InChI InChI=1S/C15H9ClN2O2/c16-12-5-3-11(4-6-12)14-18-13(15(19)20-14)8-10-2-1-7-17-9-10/h1-9H/b13-8- | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 530 | n/a | n/a | n/a | n/a | n/a | n/a |
PharmaDesign, Inc.
Curated by ChEMBL
| Assay Description Inhibition of human recombinant DAPK3 |
Bioorg Med Chem 18: 2728-34 (2010)
Article DOI: 10.1016/j.bmc.2010.02.018 BindingDB Entry DOI: 10.7270/Q2RB74R2 |
More data for this Ligand-Target Pair | |
Death-associated protein kinase 3
(Homo sapiens (Human)) | BDBM50314675
(2-(4-methyl-3-nitrophenyl)-4-(pyridin-3-ylmethylen...)Show SMILES Cc1ccc(cc1[N+]([O-])=O)C1=N\C(=C/c2cccnc2)C(=O)O1 |t:11| Show InChI InChI=1S/C16H11N3O4/c1-10-4-5-12(8-14(10)19(21)22)15-18-13(16(20)23-15)7-11-3-2-6-17-9-11/h2-9H,1H3/b13-7- | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 534 | n/a | n/a | n/a | n/a | n/a | n/a |
PharmaDesign, Inc.
Curated by ChEMBL
| Assay Description Inhibition of human recombinant DAPK3 |
Bioorg Med Chem 18: 2728-34 (2010)
Article DOI: 10.1016/j.bmc.2010.02.018 BindingDB Entry DOI: 10.7270/Q2RB74R2 |
More data for this Ligand-Target Pair | |
Death-associated protein kinase 3
(Homo sapiens (Human)) | BDBM50314663
(2-phenyl-4-(pyridin-3-ylmethylene)oxazol-5(4H)-one...)Show InChI InChI=1S/C15H10N2O2/c18-15-13(9-11-5-4-8-16-10-11)17-14(19-15)12-6-2-1-3-7-12/h1-10H/b13-9- | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 583 | n/a | n/a | n/a | n/a | n/a | n/a |
PharmaDesign, Inc.
Curated by ChEMBL
| Assay Description Inhibition of human recombinant DAPK3 |
Bioorg Med Chem 18: 2728-34 (2010)
Article DOI: 10.1016/j.bmc.2010.02.018 BindingDB Entry DOI: 10.7270/Q2RB74R2 |
More data for this Ligand-Target Pair | |
Death-associated protein kinase 3
(Homo sapiens (Human)) | BDBM50314666
(4-(pyridin-3-ylmethylene)-2-m-tolyloxazol-5(4H)-on...)Show SMILES Cc1cccc(c1)C1=N\C(=C/c2cccnc2)C(=O)O1 |t:8| Show InChI InChI=1S/C16H12N2O2/c1-11-4-2-6-13(8-11)15-18-14(16(19)20-15)9-12-5-3-7-17-10-12/h2-10H,1H3/b14-9- | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 714 | n/a | n/a | n/a | n/a | n/a | n/a |
PharmaDesign, Inc.
Curated by ChEMBL
| Assay Description Inhibition of human recombinant DAPK3 |
Bioorg Med Chem 18: 2728-34 (2010)
Article DOI: 10.1016/j.bmc.2010.02.018 BindingDB Entry DOI: 10.7270/Q2RB74R2 |
More data for this Ligand-Target Pair | |