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| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| P2X purinoceptor 7 (Homo sapiens (Human)) | BDBM50344933 ((R)-5-ethyl-2-(4-fluorophenyl)-7-isopropyl-1-(3,4,...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet  | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 24 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Antagonist activity at human P2X7 receptor by calcium flux assay | Bioorg Med Chem Lett 21: 3805-8 (2011) Article DOI: 10.1016/j.bmcl.2011.04.034 BindingDB Entry DOI: 10.7270/Q25B02SR | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| P2X purinoceptor 7 (Homo sapiens (Human)) | BDBM50344920 ((R)-1-(3,4-difluorobenzyl)-5-ethyl-7-isopropyl-2-(...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 25 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Antagonist activity at human P2X7 receptor by calcium flux assay | Bioorg Med Chem Lett 21: 3805-8 (2011) Article DOI: 10.1016/j.bmcl.2011.04.034 BindingDB Entry DOI: 10.7270/Q25B02SR | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| P2X purinoceptor 7 (Homo sapiens (Human)) | BDBM50344903 ((R)-1-(3,4-difluorobenzyl)-2-(6-(3,3-difluoropiper...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 28 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Antagonist activity at human P2X7 receptor by calcium flux assay | Bioorg Med Chem Lett 21: 3805-8 (2011) Article DOI: 10.1016/j.bmcl.2011.04.034 BindingDB Entry DOI: 10.7270/Q25B02SR | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| P2X purinoceptor 7 (Homo sapiens (Human)) | BDBM50344937 ((R)-1-(3,4-difluorobenzyl)-5-ethyl-2-(4-fluorophen...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 29 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Antagonist activity at human P2X7 receptor by calcium flux assay | Bioorg Med Chem Lett 21: 3805-8 (2011) Article DOI: 10.1016/j.bmcl.2011.04.034 BindingDB Entry DOI: 10.7270/Q25B02SR | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| P2X purinoceptor 7 (Homo sapiens (Human)) | BDBM50344914 ((R)-1-(3,4-difluorobenzyl)-5-ethyl-2-(6-fluoropyri...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 35 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Antagonist activity at human P2X7 receptor by calcium flux assay | Bioorg Med Chem Lett 21: 3805-8 (2011) Article DOI: 10.1016/j.bmcl.2011.04.034 BindingDB Entry DOI: 10.7270/Q25B02SR | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| P2X purinoceptor 7 (Homo sapiens (Human)) | BDBM50344936 ((R)-1-(2,4-difluorobenzyl)-5-ethyl-2-(4-fluorophen...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 35 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Antagonist activity at human P2X7 receptor by calcium flux assay | Bioorg Med Chem Lett 21: 3805-8 (2011) Article DOI: 10.1016/j.bmcl.2011.04.034 BindingDB Entry DOI: 10.7270/Q25B02SR | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| P2X purinoceptor 7 (Homo sapiens (Human)) | BDBM50344934 ((R)-1-(3,5-difluorobenzyl)-5-ethyl-2-(4-fluorophen...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 36 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Antagonist activity at human P2X7 receptor by calcium flux assay | Bioorg Med Chem Lett 21: 3805-8 (2011) Article DOI: 10.1016/j.bmcl.2011.04.034 BindingDB Entry DOI: 10.7270/Q25B02SR | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| P2X purinoceptor 7 (Homo sapiens (Human)) | BDBM50344918 ((R)-4-(1-(3,4-difluorobenzyl)-5-ethyl-7-isopropyl-...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 40 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Antagonist activity at human P2X7 receptor by calcium flux assay | Bioorg Med Chem Lett 21: 3805-8 (2011) Article DOI: 10.1016/j.bmcl.2011.04.034 BindingDB Entry DOI: 10.7270/Q25B02SR | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| P2X purinoceptor 7 (Homo sapiens (Human)) | BDBM50344929 ((R)-7-tert-butyl-1-(3,4-difluorobenzyl)-5-ethyl-2-...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 41 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Antagonist activity at human P2X7 receptor by calcium flux assay | Bioorg Med Chem Lett 21: 3805-8 (2011) Article DOI: 10.1016/j.bmcl.2011.04.034 BindingDB Entry DOI: 10.7270/Q25B02SR | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| P2X purinoceptor 7 (Homo sapiens (Human)) | BDBM50344913 ((R)-5-(1-(3,4-difluorobenzyl)-5-ethyl-7-isopropyl-...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 41 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Antagonist activity at human P2X7 receptor by calcium flux assay | Bioorg Med Chem Lett 21: 3805-8 (2011) Article DOI: 10.1016/j.bmcl.2011.04.034 BindingDB Entry DOI: 10.7270/Q25B02SR | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| P2X purinoceptor 7 (Homo sapiens (Human)) | BDBM50344907 ((R)-1-(3,4-difluorobenzyl)-5-ethyl-7-isopropyl-2-(...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 42 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Antagonist activity at human P2X7 receptor by calcium flux assay | Bioorg Med Chem Lett 21: 3805-8 (2011) Article DOI: 10.1016/j.bmcl.2011.04.034 BindingDB Entry DOI: 10.7270/Q25B02SR | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| P2X purinoceptor 7 (Homo sapiens (Human)) | BDBM50344906 ((R)-1-(3,4-difluorobenzyl)-2-(6-((2R,6S)-2,6-dimet...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 43 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Antagonist activity at human P2X7 receptor by calcium flux assay | Bioorg Med Chem Lett 21: 3805-8 (2011) Article DOI: 10.1016/j.bmcl.2011.04.034 BindingDB Entry DOI: 10.7270/Q25B02SR | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| P2X purinoceptor 7 (Homo sapiens (Human)) | BDBM50344926 ((R)-7-sec-butyl-1-(3,4-difluorobenzyl)-5-ethyl-2-(...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 43 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Antagonist activity at human P2X7 receptor by calcium flux assay | Bioorg Med Chem Lett 21: 3805-8 (2011) Article DOI: 10.1016/j.bmcl.2011.04.034 BindingDB Entry DOI: 10.7270/Q25B02SR | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| P2X purinoceptor 7 (Homo sapiens (Human)) | BDBM50344912 ((R)-1-(3,4-difluorobenzyl)-5-ethyl-7-isopropyl-2-(...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 50 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Antagonist activity at human P2X7 receptor by calcium flux assay | Bioorg Med Chem Lett 21: 3805-8 (2011) Article DOI: 10.1016/j.bmcl.2011.04.034 BindingDB Entry DOI: 10.7270/Q25B02SR | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| P2X purinoceptor 7 (Homo sapiens (Human)) | BDBM50344904 ((R)-1-(3,4-difluorobenzyl)-2-(6-(4,4-difluoropiper...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 51 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Antagonist activity at human P2X7 receptor by calcium flux assay | Bioorg Med Chem Lett 21: 3805-8 (2011) Article DOI: 10.1016/j.bmcl.2011.04.034 BindingDB Entry DOI: 10.7270/Q25B02SR | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| P2X purinoceptor 7 (Homo sapiens (Human)) | BDBM50344935 ((R)-5-ethyl-1-(4-fluorobenzyl)-2-(4-fluorophenyl)-...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 52 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Antagonist activity at human P2X7 receptor by calcium flux assay | Bioorg Med Chem Lett 21: 3805-8 (2011) Article DOI: 10.1016/j.bmcl.2011.04.034 BindingDB Entry DOI: 10.7270/Q25B02SR | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| P2X purinoceptor 7 (Homo sapiens (Human)) | BDBM50344928 ((R)-7-cyclopropyl-1-(3,4-difluorobenzyl)-5-ethyl-2...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 52 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Antagonist activity at human P2X7 receptor by calcium flux assay | Bioorg Med Chem Lett 21: 3805-8 (2011) Article DOI: 10.1016/j.bmcl.2011.04.034 BindingDB Entry DOI: 10.7270/Q25B02SR | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| P2X purinoceptor 7 (Homo sapiens (Human)) | BDBM50344919 ((R)-1-(3,4-difluorobenzyl)-5-ethyl-7-isopropyl-2-(...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 64 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Antagonist activity at human P2X7 receptor by calcium flux assay | Bioorg Med Chem Lett 21: 3805-8 (2011) Article DOI: 10.1016/j.bmcl.2011.04.034 BindingDB Entry DOI: 10.7270/Q25B02SR | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| P2X purinoceptor 7 (Homo sapiens (Human)) | BDBM50344910 ((R)-1-(3,4-difluorobenzyl)-5-ethyl-7-isopropyl-2-(...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 64 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Antagonist activity at human P2X7 receptor by calcium flux assay | Bioorg Med Chem Lett 21: 3805-8 (2011) Article DOI: 10.1016/j.bmcl.2011.04.034 BindingDB Entry DOI: 10.7270/Q25B02SR | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| P2X purinoceptor 7 (Homo sapiens (Human)) | BDBM50344916 ((R)-5-(1-(3,4-difluorobenzyl)-5-ethyl-7-isopropyl-...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 73 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Antagonist activity at human P2X7 receptor by calcium flux assay | Bioorg Med Chem Lett 21: 3805-8 (2011) Article DOI: 10.1016/j.bmcl.2011.04.034 BindingDB Entry DOI: 10.7270/Q25B02SR | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| P2X purinoceptor 7 (Homo sapiens (Human)) | BDBM50344905 ((R)-1-(3,4-difluorobenzyl)-5-ethyl-7-isopropyl-2-(...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 82 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Antagonist activity at human P2X7 receptor by calcium flux assay | Bioorg Med Chem Lett 21: 3805-8 (2011) Article DOI: 10.1016/j.bmcl.2011.04.034 BindingDB Entry DOI: 10.7270/Q25B02SR | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| P2X purinoceptor 7 (Homo sapiens (Human)) | BDBM50344927 ((R)-7-cyclopentyl-1-(3,4-difluorobenzyl)-5-ethyl-2...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 111 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Antagonist activity at human P2X7 receptor by calcium flux assay | Bioorg Med Chem Lett 21: 3805-8 (2011) Article DOI: 10.1016/j.bmcl.2011.04.034 BindingDB Entry DOI: 10.7270/Q25B02SR | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| P2X purinoceptor 7 (Homo sapiens (Human)) | BDBM50344932 ((R)-1-(cyclopentylmethyl)-5-ethyl-2-(4-fluoropheny...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 114 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Antagonist activity at human P2X7 receptor by calcium flux assay | Bioorg Med Chem Lett 21: 3805-8 (2011) Article DOI: 10.1016/j.bmcl.2011.04.034 BindingDB Entry DOI: 10.7270/Q25B02SR | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| P2X purinoceptor 7 (Homo sapiens (Human)) | BDBM50344917 ((R)-4-(1-(3,4-difluorobenzyl)-5-ethyl-7-isopropyl-...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 114 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Antagonist activity at human P2X7 receptor by calcium flux assay | Bioorg Med Chem Lett 21: 3805-8 (2011) Article DOI: 10.1016/j.bmcl.2011.04.034 BindingDB Entry DOI: 10.7270/Q25B02SR | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| P2X purinoceptor 7 (Homo sapiens (Human)) | BDBM50344923 (1-(3,4-difluorobenzyl)-5-ethyl-2-(4-fluorophenyl)-...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 117 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Antagonist activity at human P2X7 receptor by calcium flux assay | Bioorg Med Chem Lett 21: 3805-8 (2011) Article DOI: 10.1016/j.bmcl.2011.04.034 BindingDB Entry DOI: 10.7270/Q25B02SR | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| P2X purinoceptor 7 (Homo sapiens (Human)) | BDBM50344925 (1-(3,4-difluorobenzyl)-5-ethyl-2-(4-fluorophenyl)-...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 121 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Antagonist activity at human P2X7 receptor by calcium flux assay | Bioorg Med Chem Lett 21: 3805-8 (2011) Article DOI: 10.1016/j.bmcl.2011.04.034 BindingDB Entry DOI: 10.7270/Q25B02SR | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| P2X purinoceptor 7 (Homo sapiens (Human)) | BDBM50344911 ((R)-1-(3,4-difluorobenzyl)-5-ethyl-7-isopropyl-2-(...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 132 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Antagonist activity at human P2X7 receptor by calcium flux assay | Bioorg Med Chem Lett 21: 3805-8 (2011) Article DOI: 10.1016/j.bmcl.2011.04.034 BindingDB Entry DOI: 10.7270/Q25B02SR | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A (Homo sapiens (Human)) | BDBM50344902 (1,2-dibenzyl-5-ethyl-2',3',5,8-tetrahydrospiro[imi...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 140 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Inhibition of PDE11 | Bioorg Med Chem Lett 21: 3805-8 (2011) Article DOI: 10.1016/j.bmcl.2011.04.034 BindingDB Entry DOI: 10.7270/Q25B02SR | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| P2X purinoceptor 7 (Homo sapiens (Human)) | BDBM50344940 ((R)-1-benzyl-5-ethyl-2-(4-fluorophenyl)-7-isopropy...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 141 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Antagonist activity at human P2X7 receptor by calcium flux assay | Bioorg Med Chem Lett 21: 3805-8 (2011) Article DOI: 10.1016/j.bmcl.2011.04.034 BindingDB Entry DOI: 10.7270/Q25B02SR | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| P2X purinoceptor 7 (Homo sapiens (Human)) | BDBM50344924 (1'-(3,4-difluorobenzyl)-5'-ethyl-2'-(4-fluoropheny...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 143 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Antagonist activity at human P2X7 receptor by calcium flux assay | Bioorg Med Chem Lett 21: 3805-8 (2011) Article DOI: 10.1016/j.bmcl.2011.04.034 BindingDB Entry DOI: 10.7270/Q25B02SR | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| P2X purinoceptor 7 (Homo sapiens (Human)) | BDBM50344939 ((R)-1-benzyl-2-(4-fluorophenyl)-7-isopropyl-5-prop...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 158 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Antagonist activity at human P2X7 receptor by calcium flux assay | Bioorg Med Chem Lett 21: 3805-8 (2011) Article DOI: 10.1016/j.bmcl.2011.04.034 BindingDB Entry DOI: 10.7270/Q25B02SR | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| P2X purinoceptor 7 (Homo sapiens (Human)) | BDBM50344909 ((R)-1-(3,4-difluorobenzyl)-5-ethyl-7-isopropyl-2-(...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 207 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Antagonist activity at human P2X7 receptor by calcium flux assay | Bioorg Med Chem Lett 21: 3805-8 (2011) Article DOI: 10.1016/j.bmcl.2011.04.034 BindingDB Entry DOI: 10.7270/Q25B02SR | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| P2X purinoceptor 7 (Rattus norvegicus (Rat)) | BDBM50344902 (1,2-dibenzyl-5-ethyl-2',3',5,8-tetrahydrospiro[imi...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 233 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Antagonist activity at rat P2X7 receptor by calcium flux assay | Bioorg Med Chem Lett 21: 3805-8 (2011) Article DOI: 10.1016/j.bmcl.2011.04.034 BindingDB Entry DOI: 10.7270/Q25B02SR | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| P2X purinoceptor 7 (Homo sapiens (Human)) | BDBM50344902 (1,2-dibenzyl-5-ethyl-2',3',5,8-tetrahydrospiro[imi...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 248 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Antagonist activity at human P2X7 receptor by calcium flux assay | Bioorg Med Chem Lett 21: 3805-8 (2011) Article DOI: 10.1016/j.bmcl.2011.04.034 BindingDB Entry DOI: 10.7270/Q25B02SR | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| P2X purinoceptor 7 (Homo sapiens (Human)) | BDBM50344915 ((R)-1-(3,4-difluorobenzyl)-5-ethyl-7-isopropyl-2-(...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 252 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Antagonist activity at human P2X7 receptor by calcium flux assay | Bioorg Med Chem Lett 21: 3805-8 (2011) Article DOI: 10.1016/j.bmcl.2011.04.034 BindingDB Entry DOI: 10.7270/Q25B02SR | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| P2X purinoceptor 7 (Homo sapiens (Human)) | BDBM50344921 ((7R)-1-(3,4-difluorobenzyl)-5-ethyl-2-(2-fluorophe...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 439 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Antagonist activity at human P2X7 receptor by calcium flux assay | Bioorg Med Chem Lett 21: 3805-8 (2011) Article DOI: 10.1016/j.bmcl.2011.04.034 BindingDB Entry DOI: 10.7270/Q25B02SR | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| P2X purinoceptor 7 (Homo sapiens (Human)) | BDBM50344938 ((R)-1-benzyl-2-(4-fluorophenyl)-5,7-diisopropyl-7,...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 470 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Antagonist activity at human P2X7 receptor by calcium flux assay | Bioorg Med Chem Lett 21: 3805-8 (2011) Article DOI: 10.1016/j.bmcl.2011.04.034 BindingDB Entry DOI: 10.7270/Q25B02SR | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| P2X purinoceptor 7 (Homo sapiens (Human)) | BDBM50344908 ((R)-2-(6-aminopyridin-3-yl)-1-(3,4-difluorobenzyl)...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.24E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Antagonist activity at human P2X7 receptor by calcium flux assay | Bioorg Med Chem Lett 21: 3805-8 (2011) Article DOI: 10.1016/j.bmcl.2011.04.034 BindingDB Entry DOI: 10.7270/Q25B02SR | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| P2X purinoceptor 7 (Homo sapiens (Human)) | BDBM50344941 ((R)-1-benzyl-2-(4-fluorophenyl)-7-isopropyl-7,8-di...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.25E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Antagonist activity at human P2X7 receptor by calcium flux assay | Bioorg Med Chem Lett 21: 3805-8 (2011) Article DOI: 10.1016/j.bmcl.2011.04.034 BindingDB Entry DOI: 10.7270/Q25B02SR | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| P2X purinoceptor 7 (Homo sapiens (Human)) | BDBM50344922 ((RS)-1-(3,4-difluorobenzyl)-5-ethyl-2,7-bis(4-fluo...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.47E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Antagonist activity at human P2X7 receptor by calcium flux assay | Bioorg Med Chem Lett 21: 3805-8 (2011) Article DOI: 10.1016/j.bmcl.2011.04.034 BindingDB Entry DOI: 10.7270/Q25B02SR | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human)) | BDBM50344902 (1,2-dibenzyl-5-ethyl-2',3',5,8-tetrahydrospiro[imi...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Inhibition of human ERG by voltage-clamp electrophysiology | Bioorg Med Chem Lett 21: 3805-8 (2011) Article DOI: 10.1016/j.bmcl.2011.04.034 BindingDB Entry DOI: 10.7270/Q25B02SR | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| P2X purinoceptor 7 (Homo sapiens (Human)) | BDBM50344931 ((R)-5-ethyl-2-(4-fluorophenyl)-7-isopropyl-1-(pyri...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.21E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Antagonist activity at human P2X7 receptor by calcium flux assay | Bioorg Med Chem Lett 21: 3805-8 (2011) Article DOI: 10.1016/j.bmcl.2011.04.034 BindingDB Entry DOI: 10.7270/Q25B02SR | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| P2X purinoceptor 7 (Homo sapiens (Human)) | BDBM50344930 ((R)-5-ethyl-2-(4-fluorophenyl)-7-isopropyl-1-(pyri...) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.07E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Antagonist activity at human P2X7 receptor by calcium flux assay | Bioorg Med Chem Lett 21: 3805-8 (2011) Article DOI: 10.1016/j.bmcl.2011.04.034 BindingDB Entry DOI: 10.7270/Q25B02SR | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human)) | BDBM50344902 (1,2-dibenzyl-5-ethyl-2',3',5,8-tetrahydrospiro[imi...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 5.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories Curated by ChEMBL | Assay Description Inhibition of PDE5 | Bioorg Med Chem Lett 21: 3805-8 (2011) Article DOI: 10.1016/j.bmcl.2011.04.034 BindingDB Entry DOI: 10.7270/Q25B02SR | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
