Found 54 hits of Enzyme Inhibition Constant Data Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Cyclin-A2/Cyclin-dependent kinase 2
(Homo sapiens (Human)) | BDBM50261163
(CHEMBL4081756)Show SMILES Cc1cccc(n1)C(=O)N[C@H]1C[C@H](C1)n1cnc2c(NCc3cccc(Br)c3)ncnc12 |r,wU:12.15,10.10,(36.41,-23.55,;35.32,-24.63,;33.83,-24.23,;32.74,-25.33,;33.14,-26.81,;34.63,-27.21,;35.72,-26.12,;35.02,-28.69,;36.54,-29.01,;33.99,-29.84,;32.49,-29.52,;31.2,-30.36,;30.36,-29.07,;31.65,-28.23,;28.86,-28.74,;28.23,-27.34,;26.7,-27.5,;26.37,-29.01,;25.04,-29.78,;23.71,-29.01,;22.38,-29.78,;21.04,-29.01,;21.04,-27.47,;19.7,-26.7,;18.37,-27.47,;18.37,-29.01,;17.04,-29.78,;19.7,-29.78,;25.04,-31.32,;26.37,-32.09,;27.71,-31.32,;27.71,-29.78,)| Show InChI InChI=1S/C23H22BrN7O/c1-14-4-2-7-19(29-14)23(32)30-17-9-18(10-17)31-13-28-20-21(26-12-27-22(20)31)25-11-15-5-3-6-16(24)8-15/h2-8,12-13,17-18H,9-11H2,1H3,(H,30,32)(H,25,26,27)/t17-,18+ | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology
Curated by ChEMBL
| Assay Description
Inhibition of CDK2/CyclinA (unknown origin) using ULingt-4E-BP as substrate after 1 hr in presence of ATP by fluorescence assay |
Bioorg Med Chem Lett 27: 4399-4404 (2017)
Article DOI: 10.1016/j.bmcl.2017.08.018
BindingDB Entry DOI: 10.7270/Q2W66P60 |
More data for this
Ligand-Target Pair | |
Cyclin-dependent kinase 5 activator 1
(Homo sapiens (Human)) | BDBM50261164
(CHEMBL4103221)Show SMILES Cc1cccc(n1)C(=O)N[C@H]1C[C@H](C1)n1cnc2c(NCc3cccc(Cl)c3)ncnc12 |r,wU:12.15,10.10,(26.01,-22.02,;24.92,-23.11,;23.43,-22.71,;22.35,-23.8,;22.75,-25.29,;24.23,-25.68,;25.32,-24.6,;24.63,-27.17,;26.14,-27.49,;23.6,-28.32,;22.09,-28,;20.8,-28.83,;19.97,-27.54,;21.26,-26.71,;18.46,-27.22,;17.83,-25.81,;16.3,-25.98,;15.98,-27.48,;14.65,-28.26,;13.31,-27.48,;11.98,-28.26,;10.65,-27.48,;10.65,-25.94,;9.31,-25.18,;7.98,-25.94,;7.98,-27.48,;6.64,-28.26,;9.31,-28.26,;14.65,-29.8,;15.98,-30.56,;17.31,-29.8,;17.31,-28.26,)| Show InChI InChI=1S/C23H22ClN7O/c1-14-4-2-7-19(29-14)23(32)30-17-9-18(10-17)31-13-28-20-21(26-12-27-22(20)31)25-11-15-5-3-6-16(24)8-15/h2-8,12-13,17-18H,9-11H2,1H3,(H,30,32)(H,25,26,27)/t17-,18+ | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 2.30 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology
Curated by ChEMBL
| Assay Description
Inhibition of CDK5/p35 (unknown origin) using ULingt-4E-BP as substrate after 1 hr in presence of ATP by fluorescence assay |
Bioorg Med Chem Lett 27: 4399-4404 (2017)
Article DOI: 10.1016/j.bmcl.2017.08.018
BindingDB Entry DOI: 10.7270/Q2W66P60 |
More data for this
Ligand-Target Pair | |
Cyclin-dependent kinase 5 activator 1
(Homo sapiens (Human)) | BDBM50261163
(CHEMBL4081756)Show SMILES Cc1cccc(n1)C(=O)N[C@H]1C[C@H](C1)n1cnc2c(NCc3cccc(Br)c3)ncnc12 |r,wU:12.15,10.10,(36.41,-23.55,;35.32,-24.63,;33.83,-24.23,;32.74,-25.33,;33.14,-26.81,;34.63,-27.21,;35.72,-26.12,;35.02,-28.69,;36.54,-29.01,;33.99,-29.84,;32.49,-29.52,;31.2,-30.36,;30.36,-29.07,;31.65,-28.23,;28.86,-28.74,;28.23,-27.34,;26.7,-27.5,;26.37,-29.01,;25.04,-29.78,;23.71,-29.01,;22.38,-29.78,;21.04,-29.01,;21.04,-27.47,;19.7,-26.7,;18.37,-27.47,;18.37,-29.01,;17.04,-29.78,;19.7,-29.78,;25.04,-31.32,;26.37,-32.09,;27.71,-31.32,;27.71,-29.78,)| Show InChI InChI=1S/C23H22BrN7O/c1-14-4-2-7-19(29-14)23(32)30-17-9-18(10-17)31-13-28-20-21(26-12-27-22(20)31)25-11-15-5-3-6-16(24)8-15/h2-8,12-13,17-18H,9-11H2,1H3,(H,30,32)(H,25,26,27)/t17-,18+ | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 4.80 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology
Curated by ChEMBL
| Assay Description
Inhibition of CDK5/p35 (unknown origin) using ULingt-4E-BP as substrate after 1 hr in presence of ATP by fluorescence assay |
Bioorg Med Chem Lett 27: 4399-4404 (2017)
Article DOI: 10.1016/j.bmcl.2017.08.018
BindingDB Entry DOI: 10.7270/Q2W66P60 |
More data for this
Ligand-Target Pair | |
Cyclin-A2/Cyclin-dependent kinase 2
(Homo sapiens (Human)) | BDBM50261205
(CHEMBL4091107)Show SMILES Cc1cccc(n1)C(=O)N[C@H]1C[C@H](C1)n1cnc2c(NCc3ccc(F)cc3)ncnc12 |r,wU:12.15,10.10,(29.02,-22.38,;27.93,-23.46,;26.44,-23.06,;25.35,-24.16,;25.75,-25.64,;27.24,-26.04,;28.33,-24.95,;27.64,-27.52,;29.15,-27.85,;26.61,-28.67,;25.1,-28.35,;23.81,-29.19,;22.97,-27.9,;24.26,-27.06,;21.47,-27.58,;20.84,-26.17,;19.31,-26.33,;18.99,-27.84,;17.65,-28.61,;16.32,-27.84,;14.99,-28.61,;13.66,-27.84,;12.32,-28.61,;10.99,-27.84,;10.99,-26.3,;9.65,-25.53,;12.32,-25.53,;13.66,-26.3,;17.65,-30.15,;18.99,-30.92,;20.32,-30.15,;20.32,-28.61,)| Show InChI InChI=1S/C23H22FN7O/c1-14-3-2-4-19(29-14)23(32)30-17-9-18(10-17)31-13-28-20-21(26-12-27-22(20)31)25-11-15-5-7-16(24)8-6-15/h2-8,12-13,17-18H,9-11H2,1H3,(H,30,32)(H,25,26,27)/t17-,18+ | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 5.40 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology
Curated by ChEMBL
| Assay Description
Inhibition of CDK2/CyclinA (unknown origin) using ULingt-4E-BP as substrate after 1 hr in presence of ATP by fluorescence assay |
Bioorg Med Chem Lett 27: 4399-4404 (2017)
Article DOI: 10.1016/j.bmcl.2017.08.018
BindingDB Entry DOI: 10.7270/Q2W66P60 |
More data for this
Ligand-Target Pair | |
Cyclin-dependent kinase 5 activator 1
(Homo sapiens (Human)) | BDBM50261165
(CHEMBL4070146)Show SMILES Cc1cccc(n1)C(=O)N[C@H]1C[C@H](C1)n1cnc2c(NCc3cccc(F)c3)ncnc12 |r,wU:12.15,10.10,(31.27,-11.82,;30.17,-12.91,;28.69,-12.51,;27.6,-13.6,;28,-15.09,;29.49,-15.48,;30.57,-14.39,;29.89,-16.97,;31.39,-17.29,;28.85,-18.12,;27.35,-17.8,;26.06,-18.63,;25.22,-17.34,;26.51,-16.51,;23.71,-17.02,;23.08,-15.61,;21.55,-15.77,;21.23,-17.28,;19.9,-18.05,;18.57,-17.28,;17.23,-18.05,;15.9,-17.28,;15.9,-15.74,;14.57,-14.97,;13.24,-15.74,;13.24,-17.28,;11.9,-18.05,;14.57,-18.05,;19.9,-19.59,;21.23,-20.36,;22.56,-19.59,;22.56,-18.05,)| Show InChI InChI=1S/C23H22FN7O/c1-14-4-2-7-19(29-14)23(32)30-17-9-18(10-17)31-13-28-20-21(26-12-27-22(20)31)25-11-15-5-3-6-16(24)8-15/h2-8,12-13,17-18H,9-11H2,1H3,(H,30,32)(H,25,26,27)/t17-,18+ | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology
Curated by ChEMBL
| Assay Description
Inhibition of CDK5/p35 (unknown origin) using ULingt-4E-BP as substrate after 1 hr in presence of ATP by fluorescence assay |
Bioorg Med Chem Lett 27: 4399-4404 (2017)
Article DOI: 10.1016/j.bmcl.2017.08.018
BindingDB Entry DOI: 10.7270/Q2W66P60 |
More data for this
Ligand-Target Pair | |
Cyclin-A2/Cyclin-dependent kinase 2
(Homo sapiens (Human)) | BDBM50261164
(CHEMBL4103221)Show SMILES Cc1cccc(n1)C(=O)N[C@H]1C[C@H](C1)n1cnc2c(NCc3cccc(Cl)c3)ncnc12 |r,wU:12.15,10.10,(26.01,-22.02,;24.92,-23.11,;23.43,-22.71,;22.35,-23.8,;22.75,-25.29,;24.23,-25.68,;25.32,-24.6,;24.63,-27.17,;26.14,-27.49,;23.6,-28.32,;22.09,-28,;20.8,-28.83,;19.97,-27.54,;21.26,-26.71,;18.46,-27.22,;17.83,-25.81,;16.3,-25.98,;15.98,-27.48,;14.65,-28.26,;13.31,-27.48,;11.98,-28.26,;10.65,-27.48,;10.65,-25.94,;9.31,-25.18,;7.98,-25.94,;7.98,-27.48,;6.64,-28.26,;9.31,-28.26,;14.65,-29.8,;15.98,-30.56,;17.31,-29.8,;17.31,-28.26,)| Show InChI InChI=1S/C23H22ClN7O/c1-14-4-2-7-19(29-14)23(32)30-17-9-18(10-17)31-13-28-20-21(26-12-27-22(20)31)25-11-15-5-3-6-16(24)8-15/h2-8,12-13,17-18H,9-11H2,1H3,(H,30,32)(H,25,26,27)/t17-,18+ | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 7.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology
Curated by ChEMBL
| Assay Description
Inhibition of CDK2/CyclinA (unknown origin) using ULingt-4E-BP as substrate after 1 hr in presence of ATP by fluorescence assay |
Bioorg Med Chem Lett 27: 4399-4404 (2017)
Article DOI: 10.1016/j.bmcl.2017.08.018
BindingDB Entry DOI: 10.7270/Q2W66P60 |
More data for this
Ligand-Target Pair | |
Cyclin-dependent kinase 5 activator 1
(Homo sapiens (Human)) | BDBM50261168
(CHEMBL4067424)Show SMILES Cc1cccc(n1)C(=O)N[C@H]1C[C@H](C1)n1cnc2c(NCc3cccnc3)ncnc12 |r,wU:12.15,10.10,(29.63,-23.6,;28.54,-24.68,;27.05,-24.28,;25.97,-25.38,;26.36,-26.86,;27.85,-27.26,;28.94,-26.17,;28.25,-28.74,;29.75,-29.07,;27.22,-29.89,;25.71,-29.57,;24.42,-30.41,;23.58,-29.12,;24.87,-28.28,;22.07,-28.8,;21.45,-27.39,;19.92,-27.55,;19.6,-29.06,;18.27,-29.83,;16.93,-29.06,;15.59,-29.83,;14.26,-29.06,;12.93,-29.83,;11.6,-29.06,;11.6,-27.52,;12.93,-26.75,;14.26,-27.52,;18.27,-31.37,;19.6,-32.14,;20.93,-31.37,;20.93,-29.83,)| Show InChI InChI=1S/C22H22N8O/c1-14-4-2-6-18(28-14)22(31)29-16-8-17(9-16)30-13-27-19-20(25-12-26-21(19)30)24-11-15-5-3-7-23-10-15/h2-7,10,12-13,16-17H,8-9,11H2,1H3,(H,29,31)(H,24,25,26)/t16-,17+ | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology
Curated by ChEMBL
| Assay Description
Inhibition of CDK5/p35 (unknown origin) using ULingt-4E-BP as substrate after 1 hr in presence of ATP by fluorescence assay |
Bioorg Med Chem Lett 27: 4399-4404 (2017)
Article DOI: 10.1016/j.bmcl.2017.08.018
BindingDB Entry DOI: 10.7270/Q2W66P60 |
More data for this
Ligand-Target Pair | |
Cyclin-dependent kinase 5 activator 1
(Homo sapiens (Human)) | BDBM50261204
(CHEMBL4098255)Show SMILES Cc1cccc(n1)C(=O)N[C@H]1C[C@H](C1)n1cnc2c(NCc3ccc(F)c(F)c3)ncnc12 |r,wU:12.15,10.10,(29.23,-17.32,;28.14,-18.41,;26.65,-18.01,;25.57,-19.1,;25.97,-20.59,;27.45,-20.98,;28.54,-19.89,;27.85,-22.47,;29.36,-22.79,;26.82,-23.62,;25.31,-23.3,;24.02,-24.13,;23.19,-22.84,;24.48,-22.01,;21.68,-22.52,;21.05,-21.11,;19.52,-21.28,;19.2,-22.78,;17.87,-23.56,;16.53,-22.78,;15.2,-23.56,;13.87,-22.78,;13.87,-21.24,;12.54,-20.48,;11.2,-21.24,;9.86,-20.48,;11.2,-22.78,;9.86,-23.56,;12.54,-23.56,;17.87,-25.09,;19.2,-25.86,;20.53,-25.09,;20.53,-23.56,)| Show InChI InChI=1S/C23H21F2N7O/c1-13-3-2-4-19(30-13)23(33)31-15-8-16(9-15)32-12-29-20-21(27-11-28-22(20)32)26-10-14-5-6-17(24)18(25)7-14/h2-7,11-12,15-16H,8-10H2,1H3,(H,31,33)(H,26,27,28)/t15-,16+ | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology
Curated by ChEMBL
| Assay Description
Inhibition of CDK5/p35 (unknown origin) using ULingt-4E-BP as substrate after 1 hr in presence of ATP by fluorescence assay |
Bioorg Med Chem Lett 27: 4399-4404 (2017)
Article DOI: 10.1016/j.bmcl.2017.08.018
BindingDB Entry DOI: 10.7270/Q2W66P60 |
More data for this
Ligand-Target Pair | |
Cyclin-A2/Cyclin-dependent kinase 2
(Homo sapiens (Human)) | BDBM50261212
(CHEMBL4087174)Show SMILES FC(F)(F)c1cccc(n1)C(=O)N[C@H]1C[C@H](C1)n1cnc2c(NCc3cccnc3)ncnc12 |r,wU:15.18,13.13,(34.82,-21.98,;33.34,-21.59,;32.94,-20.11,;34.42,-20.49,;32.26,-22.68,;30.77,-22.28,;29.68,-23.37,;30.08,-24.85,;31.57,-25.26,;32.66,-24.17,;31.96,-26.74,;33.47,-27.06,;30.93,-27.89,;29.43,-27.57,;28.14,-28.41,;27.29,-27.12,;28.59,-26.27,;25.79,-26.79,;25.17,-25.39,;23.64,-25.55,;23.31,-27.06,;21.98,-27.82,;20.65,-27.06,;19.32,-27.82,;17.98,-27.06,;16.64,-27.82,;15.31,-27.06,;15.31,-25.52,;16.64,-24.74,;17.98,-25.52,;21.98,-29.36,;23.31,-30.14,;24.65,-29.36,;24.65,-27.82,)| Show InChI InChI=1S/C22H19F3N8O/c23-22(24,25)17-5-1-4-16(32-17)21(34)31-14-7-15(8-14)33-12-30-18-19(28-11-29-20(18)33)27-10-13-3-2-6-26-9-13/h1-6,9,11-12,14-15H,7-8,10H2,(H,31,34)(H,27,28,29)/t14-,15+ | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology
Curated by ChEMBL
| Assay Description
Inhibition of CDK2/CyclinA (unknown origin) using ULingt-4E-BP as substrate after 1 hr in presence of ATP by fluorescence assay |
Bioorg Med Chem Lett 27: 4399-4404 (2017)
Article DOI: 10.1016/j.bmcl.2017.08.018
BindingDB Entry DOI: 10.7270/Q2W66P60 |
More data for this
Ligand-Target Pair | |
Cyclin-A2/Cyclin-dependent kinase 2
(Homo sapiens (Human)) | BDBM50261165
(CHEMBL4070146)Show SMILES Cc1cccc(n1)C(=O)N[C@H]1C[C@H](C1)n1cnc2c(NCc3cccc(F)c3)ncnc12 |r,wU:12.15,10.10,(31.27,-11.82,;30.17,-12.91,;28.69,-12.51,;27.6,-13.6,;28,-15.09,;29.49,-15.48,;30.57,-14.39,;29.89,-16.97,;31.39,-17.29,;28.85,-18.12,;27.35,-17.8,;26.06,-18.63,;25.22,-17.34,;26.51,-16.51,;23.71,-17.02,;23.08,-15.61,;21.55,-15.77,;21.23,-17.28,;19.9,-18.05,;18.57,-17.28,;17.23,-18.05,;15.9,-17.28,;15.9,-15.74,;14.57,-14.97,;13.24,-15.74,;13.24,-17.28,;11.9,-18.05,;14.57,-18.05,;19.9,-19.59,;21.23,-20.36,;22.56,-19.59,;22.56,-18.05,)| Show InChI InChI=1S/C23H22FN7O/c1-14-4-2-7-19(29-14)23(32)30-17-9-18(10-17)31-13-28-20-21(26-12-27-22(20)31)25-11-15-5-3-6-16(24)8-15/h2-8,12-13,17-18H,9-11H2,1H3,(H,30,32)(H,25,26,27)/t17-,18+ | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology
Curated by ChEMBL
| Assay Description
Inhibition of CDK2/CyclinA (unknown origin) using ULingt-4E-BP as substrate after 1 hr in presence of ATP by fluorescence assay |
Bioorg Med Chem Lett 27: 4399-4404 (2017)
Article DOI: 10.1016/j.bmcl.2017.08.018
BindingDB Entry DOI: 10.7270/Q2W66P60 |
More data for this
Ligand-Target Pair | |
Cyclin-A2/Cyclin-dependent kinase 2
(Homo sapiens (Human)) | BDBM50261168
(CHEMBL4067424)Show SMILES Cc1cccc(n1)C(=O)N[C@H]1C[C@H](C1)n1cnc2c(NCc3cccnc3)ncnc12 |r,wU:12.15,10.10,(29.63,-23.6,;28.54,-24.68,;27.05,-24.28,;25.97,-25.38,;26.36,-26.86,;27.85,-27.26,;28.94,-26.17,;28.25,-28.74,;29.75,-29.07,;27.22,-29.89,;25.71,-29.57,;24.42,-30.41,;23.58,-29.12,;24.87,-28.28,;22.07,-28.8,;21.45,-27.39,;19.92,-27.55,;19.6,-29.06,;18.27,-29.83,;16.93,-29.06,;15.59,-29.83,;14.26,-29.06,;12.93,-29.83,;11.6,-29.06,;11.6,-27.52,;12.93,-26.75,;14.26,-27.52,;18.27,-31.37,;19.6,-32.14,;20.93,-31.37,;20.93,-29.83,)| Show InChI InChI=1S/C22H22N8O/c1-14-4-2-6-18(28-14)22(31)29-16-8-17(9-16)30-13-27-19-20(25-12-26-21(19)30)24-11-15-5-3-7-23-10-15/h2-7,10,12-13,16-17H,8-9,11H2,1H3,(H,29,31)(H,24,25,26)/t16-,17+ | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology
Curated by ChEMBL
| Assay Description
Inhibition of CDK2/CyclinA (unknown origin) using ULingt-4E-BP as substrate after 1 hr in presence of ATP by fluorescence assay |
Bioorg Med Chem Lett 27: 4399-4404 (2017)
Article DOI: 10.1016/j.bmcl.2017.08.018
BindingDB Entry DOI: 10.7270/Q2W66P60 |
More data for this
Ligand-Target Pair | |
Cyclin-A2/Cyclin-dependent kinase 2
(Homo sapiens (Human)) | BDBM50261211
(CHEMBL4094891)Show SMILES COc1cccc(Nc2ncnc3n(cnc23)[C@@H]2C[C@@H](C2)NC(=O)c2cccc(C)n2)c1 |r,wU:17.18,19.23,(16.66,-26.35,;15.34,-25.58,;15.33,-24.04,;13.98,-23.27,;13.99,-21.72,;15.34,-20.96,;16.66,-21.74,;18.01,-20.97,;19.35,-21.76,;19.35,-23.3,;20.69,-24.07,;22.02,-23.3,;22.02,-21.75,;23.17,-20.71,;22.55,-19.33,;21.02,-19.48,;20.69,-20.98,;24.67,-20.96,;25.58,-22.22,;26.82,-21.33,;25.91,-20.07,;28.34,-21.57,;29.31,-20.39,;30.84,-20.63,;28.76,-18.95,;27.24,-18.7,;26.68,-17.26,;27.67,-16.05,;29.19,-16.31,;30.18,-15.11,;29.74,-17.76,;16.66,-23.28,)| Show InChI InChI=1S/C23H23N7O2/c1-14-5-3-8-19(27-14)23(31)29-16-9-17(10-16)30-13-26-20-21(24-12-25-22(20)30)28-15-6-4-7-18(11-15)32-2/h3-8,11-13,16-17H,9-10H2,1-2H3,(H,29,31)(H,24,25,28)/t16-,17+ | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 18 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology
Curated by ChEMBL
| Assay Description
Inhibition of CDK2/CyclinA (unknown origin) using ULingt-4E-BP as substrate after 1 hr in presence of ATP by fluorescence assay |
Bioorg Med Chem Lett 27: 4399-4404 (2017)
Article DOI: 10.1016/j.bmcl.2017.08.018
BindingDB Entry DOI: 10.7270/Q2W66P60 |
More data for this
Ligand-Target Pair | |
Cyclin-T1/Cyclin-dependent kinase 9
(Homo sapiens (Human)) | BDBM50261163
(CHEMBL4081756)Show SMILES Cc1cccc(n1)C(=O)N[C@H]1C[C@H](C1)n1cnc2c(NCc3cccc(Br)c3)ncnc12 |r,wU:12.15,10.10,(36.41,-23.55,;35.32,-24.63,;33.83,-24.23,;32.74,-25.33,;33.14,-26.81,;34.63,-27.21,;35.72,-26.12,;35.02,-28.69,;36.54,-29.01,;33.99,-29.84,;32.49,-29.52,;31.2,-30.36,;30.36,-29.07,;31.65,-28.23,;28.86,-28.74,;28.23,-27.34,;26.7,-27.5,;26.37,-29.01,;25.04,-29.78,;23.71,-29.01,;22.38,-29.78,;21.04,-29.01,;21.04,-27.47,;19.7,-26.7,;18.37,-27.47,;18.37,-29.01,;17.04,-29.78,;19.7,-29.78,;25.04,-31.32,;26.37,-32.09,;27.71,-31.32,;27.71,-29.78,)| Show InChI InChI=1S/C23H22BrN7O/c1-14-4-2-7-19(29-14)23(32)30-17-9-18(10-17)31-13-28-20-21(26-12-27-22(20)31)25-11-15-5-3-6-16(24)8-15/h2-8,12-13,17-18H,9-11H2,1H3,(H,30,32)(H,25,26,27)/t17-,18+ | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 19 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology
Curated by ChEMBL
| Assay Description
Inhibition of human CDK9/CyclinT1 |
Bioorg Med Chem Lett 27: 4399-4404 (2017)
Article DOI: 10.1016/j.bmcl.2017.08.018
BindingDB Entry DOI: 10.7270/Q2W66P60 |
More data for this
Ligand-Target Pair | |
Cyclin-dependent kinase/G2/mitotic-specific cyclin- 1
(Homo sapiens (Human)) | BDBM50261164
(CHEMBL4103221)Show SMILES Cc1cccc(n1)C(=O)N[C@H]1C[C@H](C1)n1cnc2c(NCc3cccc(Cl)c3)ncnc12 |r,wU:12.15,10.10,(26.01,-22.02,;24.92,-23.11,;23.43,-22.71,;22.35,-23.8,;22.75,-25.29,;24.23,-25.68,;25.32,-24.6,;24.63,-27.17,;26.14,-27.49,;23.6,-28.32,;22.09,-28,;20.8,-28.83,;19.97,-27.54,;21.26,-26.71,;18.46,-27.22,;17.83,-25.81,;16.3,-25.98,;15.98,-27.48,;14.65,-28.26,;13.31,-27.48,;11.98,-28.26,;10.65,-27.48,;10.65,-25.94,;9.31,-25.18,;7.98,-25.94,;7.98,-27.48,;6.64,-28.26,;9.31,-28.26,;14.65,-29.8,;15.98,-30.56,;17.31,-29.8,;17.31,-28.26,)| Show InChI InChI=1S/C23H22ClN7O/c1-14-4-2-7-19(29-14)23(32)30-17-9-18(10-17)31-13-28-20-21(26-12-27-22(20)31)25-11-15-5-3-6-16(24)8-15/h2-8,12-13,17-18H,9-11H2,1H3,(H,30,32)(H,25,26,27)/t17-,18+ | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 23 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology
Curated by ChEMBL
| Assay Description
Inhibition of human CDK1/CyclinB |
Bioorg Med Chem Lett 27: 4399-4404 (2017)
Article DOI: 10.1016/j.bmcl.2017.08.018
BindingDB Entry DOI: 10.7270/Q2W66P60 |
More data for this
Ligand-Target Pair | |
Cyclin-dependent kinase 5 activator 1
(Homo sapiens (Human)) | BDBM50261212
(CHEMBL4087174)Show SMILES FC(F)(F)c1cccc(n1)C(=O)N[C@H]1C[C@H](C1)n1cnc2c(NCc3cccnc3)ncnc12 |r,wU:15.18,13.13,(34.82,-21.98,;33.34,-21.59,;32.94,-20.11,;34.42,-20.49,;32.26,-22.68,;30.77,-22.28,;29.68,-23.37,;30.08,-24.85,;31.57,-25.26,;32.66,-24.17,;31.96,-26.74,;33.47,-27.06,;30.93,-27.89,;29.43,-27.57,;28.14,-28.41,;27.29,-27.12,;28.59,-26.27,;25.79,-26.79,;25.17,-25.39,;23.64,-25.55,;23.31,-27.06,;21.98,-27.82,;20.65,-27.06,;19.32,-27.82,;17.98,-27.06,;16.64,-27.82,;15.31,-27.06,;15.31,-25.52,;16.64,-24.74,;17.98,-25.52,;21.98,-29.36,;23.31,-30.14,;24.65,-29.36,;24.65,-27.82,)| Show InChI InChI=1S/C22H19F3N8O/c23-22(24,25)17-5-1-4-16(32-17)21(34)31-14-7-15(8-14)33-12-30-18-19(28-11-29-20(18)33)27-10-13-3-2-6-26-9-13/h1-6,9,11-12,14-15H,7-8,10H2,(H,31,34)(H,27,28,29)/t14-,15+ | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 23 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology
Curated by ChEMBL
| Assay Description
Inhibition of CDK5/p35 (unknown origin) using ULingt-4E-BP as substrate after 1 hr in presence of ATP by fluorescence assay |
Bioorg Med Chem Lett 27: 4399-4404 (2017)
Article DOI: 10.1016/j.bmcl.2017.08.018
BindingDB Entry DOI: 10.7270/Q2W66P60 |
More data for this
Ligand-Target Pair | |
Cyclin-dependent kinase/G2/mitotic-specific cyclin- 1
(Homo sapiens (Human)) | BDBM50261163
(CHEMBL4081756)Show SMILES Cc1cccc(n1)C(=O)N[C@H]1C[C@H](C1)n1cnc2c(NCc3cccc(Br)c3)ncnc12 |r,wU:12.15,10.10,(36.41,-23.55,;35.32,-24.63,;33.83,-24.23,;32.74,-25.33,;33.14,-26.81,;34.63,-27.21,;35.72,-26.12,;35.02,-28.69,;36.54,-29.01,;33.99,-29.84,;32.49,-29.52,;31.2,-30.36,;30.36,-29.07,;31.65,-28.23,;28.86,-28.74,;28.23,-27.34,;26.7,-27.5,;26.37,-29.01,;25.04,-29.78,;23.71,-29.01,;22.38,-29.78,;21.04,-29.01,;21.04,-27.47,;19.7,-26.7,;18.37,-27.47,;18.37,-29.01,;17.04,-29.78,;19.7,-29.78,;25.04,-31.32,;26.37,-32.09,;27.71,-31.32,;27.71,-29.78,)| Show InChI InChI=1S/C23H22BrN7O/c1-14-4-2-7-19(29-14)23(32)30-17-9-18(10-17)31-13-28-20-21(26-12-27-22(20)31)25-11-15-5-3-6-16(24)8-15/h2-8,12-13,17-18H,9-11H2,1H3,(H,30,32)(H,25,26,27)/t17-,18+ | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 24 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology
Curated by ChEMBL
| Assay Description
Inhibition of human CDK1/CyclinB |
Bioorg Med Chem Lett 27: 4399-4404 (2017)
Article DOI: 10.1016/j.bmcl.2017.08.018
BindingDB Entry DOI: 10.7270/Q2W66P60 |
More data for this
Ligand-Target Pair | |
Cyclin-dependent kinase 5 activator 1
(Homo sapiens (Human)) | BDBM50261189
(CHEMBL4063385)Show SMILES Cc1cccc(n1)C(=O)N[C@H]1C[C@H](C1)n1cnc2c(NCC3CCCCC3)ncnc12 |r,wU:12.15,10.10,(34.03,-20.69,;32.94,-21.78,;31.45,-21.38,;30.37,-22.47,;30.76,-23.96,;32.25,-24.35,;33.34,-23.27,;32.65,-25.84,;34.15,-26.16,;31.62,-26.99,;30.11,-26.67,;28.82,-27.5,;27.98,-26.21,;29.27,-25.38,;26.47,-25.89,;25.85,-24.49,;24.32,-24.65,;24,-26.15,;22.67,-26.93,;21.33,-26.15,;20,-26.93,;18.66,-26.15,;17.33,-26.93,;16,-26.15,;16,-24.61,;17.33,-23.85,;18.66,-24.61,;22.67,-28.47,;24,-29.23,;25.33,-28.47,;25.33,-26.93,)| Show InChI InChI=1S/C23H29N7O/c1-15-6-5-9-19(28-15)23(31)29-17-10-18(11-17)30-14-27-20-21(25-13-26-22(20)30)24-12-16-7-3-2-4-8-16/h5-6,9,13-14,16-18H,2-4,7-8,10-12H2,1H3,(H,29,31)(H,24,25,26)/t17-,18+ | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 25 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology
Curated by ChEMBL
| Assay Description
Inhibition of CDK5/p35 (unknown origin) using ULingt-4E-BP as substrate after 1 hr in presence of ATP by fluorescence assay |
Bioorg Med Chem Lett 27: 4399-4404 (2017)
Article DOI: 10.1016/j.bmcl.2017.08.018
BindingDB Entry DOI: 10.7270/Q2W66P60 |
More data for this
Ligand-Target Pair | |
Cyclin-T1/Cyclin-dependent kinase 9
(Homo sapiens (Human)) | BDBM50261164
(CHEMBL4103221)Show SMILES Cc1cccc(n1)C(=O)N[C@H]1C[C@H](C1)n1cnc2c(NCc3cccc(Cl)c3)ncnc12 |r,wU:12.15,10.10,(26.01,-22.02,;24.92,-23.11,;23.43,-22.71,;22.35,-23.8,;22.75,-25.29,;24.23,-25.68,;25.32,-24.6,;24.63,-27.17,;26.14,-27.49,;23.6,-28.32,;22.09,-28,;20.8,-28.83,;19.97,-27.54,;21.26,-26.71,;18.46,-27.22,;17.83,-25.81,;16.3,-25.98,;15.98,-27.48,;14.65,-28.26,;13.31,-27.48,;11.98,-28.26,;10.65,-27.48,;10.65,-25.94,;9.31,-25.18,;7.98,-25.94,;7.98,-27.48,;6.64,-28.26,;9.31,-28.26,;14.65,-29.8,;15.98,-30.56,;17.31,-29.8,;17.31,-28.26,)| Show InChI InChI=1S/C23H22ClN7O/c1-14-4-2-7-19(29-14)23(32)30-17-9-18(10-17)31-13-28-20-21(26-12-27-22(20)31)25-11-15-5-3-6-16(24)8-15/h2-8,12-13,17-18H,9-11H2,1H3,(H,30,32)(H,25,26,27)/t17-,18+ | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 27 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology
Curated by ChEMBL
| Assay Description
Inhibition of human CDK9/CyclinT1 |
Bioorg Med Chem Lett 27: 4399-4404 (2017)
Article DOI: 10.1016/j.bmcl.2017.08.018
BindingDB Entry DOI: 10.7270/Q2W66P60 |
More data for this
Ligand-Target Pair | |
Cyclin-dependent kinase 5 activator 1
(Homo sapiens (Human)) | BDBM50261170
(CHEMBL4092920)Show SMILES CC(=O)N[C@H]1CC[C@H](CC1)Nc1ncnc2n(cnc12)[C@@H]1C[C@@H](C1)NC(=O)c1cccc(C)n1 |r,wU:4.3,7.10,20.22,22.27,(16.83,-30.61,;16.84,-32.15,;15.51,-32.93,;18.17,-32.92,;19.5,-32.14,;19.5,-30.6,;20.83,-29.83,;22.16,-30.59,;22.17,-32.13,;20.84,-32.91,;23.5,-29.82,;24.83,-30.58,;24.84,-32.12,;26.18,-32.88,;27.5,-32.11,;27.5,-30.57,;28.64,-29.53,;28.01,-28.13,;26.48,-28.3,;26.16,-29.8,;30.14,-29.85,;30.99,-31.14,;32.28,-30.29,;31.43,-29,;33.79,-30.6,;34.81,-29.46,;36.32,-29.77,;34.4,-27.97,;32.91,-27.58,;32.52,-26.09,;33.6,-25,;35.09,-25.39,;36.17,-24.3,;35.49,-26.87,)| Show InChI InChI=1S/C24H30N8O2/c1-14-4-3-5-20(28-14)24(34)31-18-10-19(11-18)32-13-27-21-22(25-12-26-23(21)32)30-17-8-6-16(7-9-17)29-15(2)33/h3-5,12-13,16-19H,6-11H2,1-2H3,(H,29,33)(H,31,34)(H,25,26,30)/t16-,17+,18-,19+ | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 27 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology
Curated by ChEMBL
| Assay Description
Inhibition of CDK5/p35 (unknown origin) using ULingt-4E-BP as substrate after 1 hr in presence of ATP by fluorescence assay |
Bioorg Med Chem Lett 27: 4399-4404 (2017)
Article DOI: 10.1016/j.bmcl.2017.08.018
BindingDB Entry DOI: 10.7270/Q2W66P60 |
More data for this
Ligand-Target Pair | |
Cyclin-A2/Cyclin-dependent kinase 2
(Homo sapiens (Human)) | BDBM50261204
(CHEMBL4098255)Show SMILES Cc1cccc(n1)C(=O)N[C@H]1C[C@H](C1)n1cnc2c(NCc3ccc(F)c(F)c3)ncnc12 |r,wU:12.15,10.10,(29.23,-17.32,;28.14,-18.41,;26.65,-18.01,;25.57,-19.1,;25.97,-20.59,;27.45,-20.98,;28.54,-19.89,;27.85,-22.47,;29.36,-22.79,;26.82,-23.62,;25.31,-23.3,;24.02,-24.13,;23.19,-22.84,;24.48,-22.01,;21.68,-22.52,;21.05,-21.11,;19.52,-21.28,;19.2,-22.78,;17.87,-23.56,;16.53,-22.78,;15.2,-23.56,;13.87,-22.78,;13.87,-21.24,;12.54,-20.48,;11.2,-21.24,;9.86,-20.48,;11.2,-22.78,;9.86,-23.56,;12.54,-23.56,;17.87,-25.09,;19.2,-25.86,;20.53,-25.09,;20.53,-23.56,)| Show InChI InChI=1S/C23H21F2N7O/c1-13-3-2-4-19(30-13)23(33)31-15-8-16(9-15)32-12-29-20-21(27-11-28-22(20)32)26-10-14-5-6-17(24)18(25)7-14/h2-7,11-12,15-16H,8-10H2,1H3,(H,31,33)(H,26,27,28)/t15-,16+ | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 29 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology
Curated by ChEMBL
| Assay Description
Inhibition of CDK2/CyclinA (unknown origin) using ULingt-4E-BP as substrate after 1 hr in presence of ATP by fluorescence assay |
Bioorg Med Chem Lett 27: 4399-4404 (2017)
Article DOI: 10.1016/j.bmcl.2017.08.018
BindingDB Entry DOI: 10.7270/Q2W66P60 |
More data for this
Ligand-Target Pair | |
Cyclin-dependent kinase 5 activator 1
(Homo sapiens (Human)) | BDBM50261205
(CHEMBL4091107)Show SMILES Cc1cccc(n1)C(=O)N[C@H]1C[C@H](C1)n1cnc2c(NCc3ccc(F)cc3)ncnc12 |r,wU:12.15,10.10,(29.02,-22.38,;27.93,-23.46,;26.44,-23.06,;25.35,-24.16,;25.75,-25.64,;27.24,-26.04,;28.33,-24.95,;27.64,-27.52,;29.15,-27.85,;26.61,-28.67,;25.1,-28.35,;23.81,-29.19,;22.97,-27.9,;24.26,-27.06,;21.47,-27.58,;20.84,-26.17,;19.31,-26.33,;18.99,-27.84,;17.65,-28.61,;16.32,-27.84,;14.99,-28.61,;13.66,-27.84,;12.32,-28.61,;10.99,-27.84,;10.99,-26.3,;9.65,-25.53,;12.32,-25.53,;13.66,-26.3,;17.65,-30.15,;18.99,-30.92,;20.32,-30.15,;20.32,-28.61,)| Show InChI InChI=1S/C23H22FN7O/c1-14-3-2-4-19(29-14)23(32)30-17-9-18(10-17)31-13-28-20-21(26-12-27-22(20)31)25-11-15-5-7-16(24)8-6-15/h2-8,12-13,17-18H,9-11H2,1H3,(H,30,32)(H,25,26,27)/t17-,18+ | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology
Curated by ChEMBL
| Assay Description
Inhibition of CDK5/p35 (unknown origin) using ULingt-4E-BP as substrate after 1 hr in presence of ATP by fluorescence assay |
Bioorg Med Chem Lett 27: 4399-4404 (2017)
Article DOI: 10.1016/j.bmcl.2017.08.018
BindingDB Entry DOI: 10.7270/Q2W66P60 |
More data for this
Ligand-Target Pair | |
Cyclin-dependent kinase 5 activator 1
(Homo sapiens (Human)) | BDBM50261169
(CHEMBL4076545)Show SMILES CC(=O)N[C@H]1CC[C@@H](CC1)Nc1ncnc2n(cnc12)[C@@H]1C[C@@H](C1)NC(=O)c1cccc(C)n1 |r,wU:7.10,20.22,22.27,wD:4.3,(16.83,-30.61,;16.84,-32.15,;15.51,-32.93,;18.17,-32.92,;19.5,-32.14,;20.84,-32.91,;22.17,-32.13,;22.16,-30.59,;20.83,-29.83,;19.5,-30.6,;23.5,-29.82,;24.83,-30.58,;24.84,-32.12,;26.18,-32.88,;27.5,-32.11,;27.5,-30.57,;28.64,-29.53,;28.01,-28.13,;26.48,-28.3,;26.16,-29.8,;30.14,-29.85,;30.99,-31.14,;32.28,-30.29,;31.43,-29,;33.79,-30.6,;34.81,-29.46,;36.32,-29.77,;34.4,-27.97,;32.91,-27.58,;32.52,-26.09,;33.6,-25,;35.09,-25.39,;36.17,-24.3,;35.49,-26.87,)| Show InChI InChI=1S/C24H30N8O2/c1-14-4-3-5-20(28-14)24(34)31-18-10-19(11-18)32-13-27-21-22(25-12-26-23(21)32)30-17-8-6-16(7-9-17)29-15(2)33/h3-5,12-13,16-19H,6-11H2,1-2H3,(H,29,33)(H,31,34)(H,25,26,30)/t16-,17-,18-,19+ | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology
Curated by ChEMBL
| Assay Description
Inhibition of CDK5/p35 (unknown origin) using ULingt-4E-BP as substrate after 1 hr in presence of ATP by fluorescence assay |
Bioorg Med Chem Lett 27: 4399-4404 (2017)
Article DOI: 10.1016/j.bmcl.2017.08.018
BindingDB Entry DOI: 10.7270/Q2W66P60 |
More data for this
Ligand-Target Pair | |
Cyclin-dependent kinase 5 activator 1
(Homo sapiens (Human)) | BDBM50261167
(CHEMBL4105016)Show SMILES O=C(N[C@H]1C[C@H](C1)n1cnc2c(NCc3cccnc3)ncnc12)c1cccc(n1)-c1ccccc1 |r,wU:5.7,3.2,(29.63,-26.83,;28.12,-26.52,;27.09,-27.66,;25.59,-27.34,;24.29,-28.19,;23.45,-26.89,;24.74,-26.05,;21.95,-26.58,;21.32,-25.17,;19.78,-25.33,;19.46,-26.84,;18.13,-27.61,;16.8,-26.84,;15.47,-27.61,;14.13,-26.84,;12.8,-27.62,;11.47,-26.85,;11.47,-25.31,;12.8,-24.54,;14.13,-25.3,;18.13,-29.15,;19.47,-29.92,;20.81,-29.15,;20.81,-27.61,;27.72,-25.03,;26.23,-24.63,;25.83,-23.15,;26.92,-22.06,;28.41,-22.45,;28.8,-23.94,;29.49,-21.36,;29.09,-19.88,;30.18,-18.79,;31.67,-19.18,;32.06,-20.67,;30.98,-21.76,)| Show InChI InChI=1S/C27H24N8O/c36-27(23-10-4-9-22(34-23)19-7-2-1-3-8-19)33-20-12-21(13-20)35-17-32-24-25(30-16-31-26(24)35)29-15-18-6-5-11-28-14-18/h1-11,14,16-17,20-21H,12-13,15H2,(H,33,36)(H,29,30,31)/t20-,21+ | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 31 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology
Curated by ChEMBL
| Assay Description
Inhibition of CDK5/p35 (unknown origin) using ULingt-4E-BP as substrate after 1 hr in presence of ATP by fluorescence assay |
Bioorg Med Chem Lett 27: 4399-4404 (2017)
Article DOI: 10.1016/j.bmcl.2017.08.018
BindingDB Entry DOI: 10.7270/Q2W66P60 |
More data for this
Ligand-Target Pair | |
Cyclin-dependent kinase 5 activator 1
(Homo sapiens (Human)) | BDBM50261203
(CHEMBL4067461)Show SMILES Cc1cccc(n1)C(=O)N[C@H]1C[C@H](C1)n1cnc2c(NCc3ccc(Cl)c(Cl)c3)ncnc12 |r,wU:12.15,10.10,(32.81,-21.74,;31.71,-22.82,;30.22,-22.42,;29.14,-23.52,;29.54,-25,;31.02,-25.4,;32.11,-24.31,;31.42,-26.88,;32.93,-27.21,;30.39,-28.04,;28.88,-27.71,;27.59,-28.55,;26.76,-27.26,;28.05,-26.42,;25.25,-26.94,;24.62,-25.53,;23.09,-25.69,;22.77,-27.2,;21.44,-27.97,;20.1,-27.2,;18.77,-27.97,;17.44,-27.2,;17.44,-25.66,;16.1,-24.89,;14.77,-25.66,;13.43,-24.89,;14.77,-27.2,;13.43,-27.97,;16.1,-27.97,;21.44,-29.51,;22.77,-30.28,;24.1,-29.51,;24.1,-27.97,)| Show InChI InChI=1S/C23H21Cl2N7O/c1-13-3-2-4-19(30-13)23(33)31-15-8-16(9-15)32-12-29-20-21(27-11-28-22(20)32)26-10-14-5-6-17(24)18(25)7-14/h2-7,11-12,15-16H,8-10H2,1H3,(H,31,33)(H,26,27,28)/t15-,16+ | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 34 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology
Curated by ChEMBL
| Assay Description
Inhibition of CDK5/p35 (unknown origin) using ULingt-4E-BP as substrate after 1 hr in presence of ATP by fluorescence assay |
Bioorg Med Chem Lett 27: 4399-4404 (2017)
Article DOI: 10.1016/j.bmcl.2017.08.018
BindingDB Entry DOI: 10.7270/Q2W66P60 |
More data for this
Ligand-Target Pair | |
Cyclin-A2/Cyclin-dependent kinase 2
(Homo sapiens (Human)) | BDBM50261167
(CHEMBL4105016)Show SMILES O=C(N[C@H]1C[C@H](C1)n1cnc2c(NCc3cccnc3)ncnc12)c1cccc(n1)-c1ccccc1 |r,wU:5.7,3.2,(29.63,-26.83,;28.12,-26.52,;27.09,-27.66,;25.59,-27.34,;24.29,-28.19,;23.45,-26.89,;24.74,-26.05,;21.95,-26.58,;21.32,-25.17,;19.78,-25.33,;19.46,-26.84,;18.13,-27.61,;16.8,-26.84,;15.47,-27.61,;14.13,-26.84,;12.8,-27.62,;11.47,-26.85,;11.47,-25.31,;12.8,-24.54,;14.13,-25.3,;18.13,-29.15,;19.47,-29.92,;20.81,-29.15,;20.81,-27.61,;27.72,-25.03,;26.23,-24.63,;25.83,-23.15,;26.92,-22.06,;28.41,-22.45,;28.8,-23.94,;29.49,-21.36,;29.09,-19.88,;30.18,-18.79,;31.67,-19.18,;32.06,-20.67,;30.98,-21.76,)| Show InChI InChI=1S/C27H24N8O/c36-27(23-10-4-9-22(34-23)19-7-2-1-3-8-19)33-20-12-21(13-20)35-17-32-24-25(30-16-31-26(24)35)29-15-18-6-5-11-28-14-18/h1-11,14,16-17,20-21H,12-13,15H2,(H,33,36)(H,29,30,31)/t20-,21+ | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 38 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology
Curated by ChEMBL
| Assay Description
Inhibition of CDK2/CyclinA (unknown origin) using ULingt-4E-BP as substrate after 1 hr in presence of ATP by fluorescence assay |
Bioorg Med Chem Lett 27: 4399-4404 (2017)
Article DOI: 10.1016/j.bmcl.2017.08.018
BindingDB Entry DOI: 10.7270/Q2W66P60 |
More data for this
Ligand-Target Pair | |
Cyclin-A2/Cyclin-dependent kinase 2
(Homo sapiens (Human)) | BDBM50261213
(CHEMBL4072013)Show SMILES Cc1cccc(n1)C(=O)N[C@H]1C[C@H](C1)n1cnc2c(NCC3CCNCC3)ncnc12 |r,wU:12.15,10.10,(35.5,-21.79,;34.42,-22.88,;32.93,-22.48,;31.84,-23.57,;32.24,-25.06,;33.72,-25.45,;34.81,-24.37,;34.13,-26.94,;35.63,-27.26,;33.1,-28.09,;31.59,-27.77,;30.29,-28.6,;29.46,-27.31,;30.75,-26.48,;27.95,-26.99,;27.32,-25.59,;25.79,-25.75,;25.47,-27.25,;24.14,-28.03,;22.81,-27.25,;21.47,-28.03,;20.14,-27.25,;20.14,-25.71,;18.81,-24.95,;17.48,-25.71,;17.48,-27.25,;18.81,-28.03,;24.14,-29.57,;25.47,-30.33,;26.81,-29.57,;26.81,-28.03,)| Show InChI InChI=1S/C22H28N8O/c1-14-3-2-4-18(28-14)22(31)29-16-9-17(10-16)30-13-27-19-20(25-12-26-21(19)30)24-11-15-5-7-23-8-6-15/h2-4,12-13,15-17,23H,5-11H2,1H3,(H,29,31)(H,24,25,26)/t16-,17+ | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 48 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology
Curated by ChEMBL
| Assay Description
Inhibition of CDK2/CyclinA (unknown origin) using ULingt-4E-BP as substrate after 1 hr in presence of ATP by fluorescence assay |
Bioorg Med Chem Lett 27: 4399-4404 (2017)
Article DOI: 10.1016/j.bmcl.2017.08.018
BindingDB Entry DOI: 10.7270/Q2W66P60 |
More data for this
Ligand-Target Pair | |
Cyclin-A2/Cyclin-dependent kinase 2
(Homo sapiens (Human)) | BDBM50261189
(CHEMBL4063385)Show SMILES Cc1cccc(n1)C(=O)N[C@H]1C[C@H](C1)n1cnc2c(NCC3CCCCC3)ncnc12 |r,wU:12.15,10.10,(34.03,-20.69,;32.94,-21.78,;31.45,-21.38,;30.37,-22.47,;30.76,-23.96,;32.25,-24.35,;33.34,-23.27,;32.65,-25.84,;34.15,-26.16,;31.62,-26.99,;30.11,-26.67,;28.82,-27.5,;27.98,-26.21,;29.27,-25.38,;26.47,-25.89,;25.85,-24.49,;24.32,-24.65,;24,-26.15,;22.67,-26.93,;21.33,-26.15,;20,-26.93,;18.66,-26.15,;17.33,-26.93,;16,-26.15,;16,-24.61,;17.33,-23.85,;18.66,-24.61,;22.67,-28.47,;24,-29.23,;25.33,-28.47,;25.33,-26.93,)| Show InChI InChI=1S/C23H29N7O/c1-15-6-5-9-19(28-15)23(31)29-17-10-18(11-17)30-14-27-20-21(25-13-26-22(20)30)24-12-16-7-3-2-4-8-16/h5-6,9,13-14,16-18H,2-4,7-8,10-12H2,1H3,(H,29,31)(H,24,25,26)/t17-,18+ | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 49 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology
Curated by ChEMBL
| Assay Description
Inhibition of CDK2/CyclinA (unknown origin) using ULingt-4E-BP as substrate after 1 hr in presence of ATP by fluorescence assay |
Bioorg Med Chem Lett 27: 4399-4404 (2017)
Article DOI: 10.1016/j.bmcl.2017.08.018
BindingDB Entry DOI: 10.7270/Q2W66P60 |
More data for this
Ligand-Target Pair | |
Cyclin-A2/Cyclin-dependent kinase 2
(Homo sapiens (Human)) | BDBM50261198
(CHEMBL4091242)Show SMILES COc1ccc(Nc2ncnc3n(cnc23)[C@@H]2C[C@@H](C2)NC(=O)c2cccc(C)n2)cc1OC |r,wU:16.17,18.22,(11.31,-24.61,;12.65,-25.37,;13.98,-24.58,;13.97,-23.04,;15.29,-22.27,;16.63,-23.02,;17.96,-22.24,;19.3,-22.99,;19.32,-24.53,;20.66,-25.29,;21.98,-24.5,;21.96,-22.96,;23.1,-21.92,;22.46,-20.52,;20.93,-20.7,;20.62,-22.21,;24.61,-22.23,;25.46,-23.51,;26.74,-22.66,;25.9,-21.38,;28.25,-22.96,;29.28,-21.81,;30.79,-22.12,;28.86,-20.33,;27.37,-19.94,;26.95,-18.46,;28.03,-17.36,;29.52,-17.75,;30.61,-16.65,;29.94,-19.23,;16.65,-24.56,;15.33,-25.34,;15.34,-26.89,;14.02,-27.66,)| Show InChI InChI=1S/C24H25N7O3/c1-14-5-4-6-18(28-14)24(32)30-16-9-17(10-16)31-13-27-21-22(25-12-26-23(21)31)29-15-7-8-19(33-2)20(11-15)34-3/h4-8,11-13,16-17H,9-10H2,1-3H3,(H,30,32)(H,25,26,29)/t16-,17+ | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Patents
| Article
PubMed
| n/a | n/a | 54 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology
Curated by ChEMBL
| Assay Description
Inhibition of CDK2/CyclinA (unknown origin) using ULingt-4E-BP as substrate after 1 hr in presence of ATP by fluorescence assay |
Bioorg Med Chem Lett 27: 4399-4404 (2017)
Article DOI: 10.1016/j.bmcl.2017.08.018
BindingDB Entry DOI: 10.7270/Q2W66P60 |
More data for this
Ligand-Target Pair | |
Cyclin-dependent kinase 5 activator 1
(Homo sapiens (Human)) | BDBM50261187
(CHEMBL4082490)Show SMILES Cc1cccc(n1)C(=O)N[C@H]1C[C@H](C1)n1cnc2c(NC3CCN(CC3)C(=O)OC(C)(C)C)ncnc12 |r,wU:10.10,12.15,(35.5,-22.63,;34.42,-23.72,;32.93,-23.33,;31.84,-24.42,;32.24,-25.9,;33.73,-26.3,;34.82,-25.21,;34.13,-27.79,;35.63,-28.1,;33.1,-28.93,;31.59,-28.61,;30.31,-29.46,;29.46,-28.16,;30.75,-27.33,;27.95,-27.85,;27.33,-26.44,;25.8,-26.6,;25.48,-28.11,;24.15,-28.88,;22.81,-28.11,;21.47,-28.89,;20.14,-28.12,;18.81,-28.89,;18.81,-30.43,;20.14,-31.2,;21.48,-30.43,;17.48,-31.2,;16.15,-30.44,;17.48,-32.74,;16.15,-33.52,;16.16,-35.05,;14.82,-32.76,;14.81,-34.27,;24.15,-30.42,;25.48,-31.19,;26.82,-30.42,;26.81,-28.88,)| Show InChI InChI=1S/C26H34N8O3/c1-16-6-5-7-20(30-16)24(35)32-18-12-19(13-18)34-15-29-21-22(27-14-28-23(21)34)31-17-8-10-33(11-9-17)25(36)37-26(2,3)4/h5-7,14-15,17-19H,8-13H2,1-4H3,(H,32,35)(H,27,28,31)/t18-,19+ | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 66 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology
Curated by ChEMBL
| Assay Description
Inhibition of CDK5/p35 (unknown origin) using ULingt-4E-BP as substrate after 1 hr in presence of ATP by fluorescence assay |
Bioorg Med Chem Lett 27: 4399-4404 (2017)
Article DOI: 10.1016/j.bmcl.2017.08.018
BindingDB Entry DOI: 10.7270/Q2W66P60 |
More data for this
Ligand-Target Pair | |
Cyclin-dependent kinase 5 activator 1
(Homo sapiens (Human)) | BDBM50261211
(CHEMBL4094891)Show SMILES COc1cccc(Nc2ncnc3n(cnc23)[C@@H]2C[C@@H](C2)NC(=O)c2cccc(C)n2)c1 |r,wU:17.18,19.23,(16.66,-26.35,;15.34,-25.58,;15.33,-24.04,;13.98,-23.27,;13.99,-21.72,;15.34,-20.96,;16.66,-21.74,;18.01,-20.97,;19.35,-21.76,;19.35,-23.3,;20.69,-24.07,;22.02,-23.3,;22.02,-21.75,;23.17,-20.71,;22.55,-19.33,;21.02,-19.48,;20.69,-20.98,;24.67,-20.96,;25.58,-22.22,;26.82,-21.33,;25.91,-20.07,;28.34,-21.57,;29.31,-20.39,;30.84,-20.63,;28.76,-18.95,;27.24,-18.7,;26.68,-17.26,;27.67,-16.05,;29.19,-16.31,;30.18,-15.11,;29.74,-17.76,;16.66,-23.28,)| Show InChI InChI=1S/C23H23N7O2/c1-14-5-3-8-19(27-14)23(31)29-16-9-17(10-16)30-13-26-20-21(24-12-25-22(20)30)28-15-6-4-7-18(11-15)32-2/h3-8,11-13,16-17H,9-10H2,1-2H3,(H,29,31)(H,24,25,28)/t16-,17+ | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 67 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology
Curated by ChEMBL
| Assay Description
Inhibition of CDK5/p35 (unknown origin) using ULingt-4E-BP as substrate after 1 hr in presence of ATP by fluorescence assay |
Bioorg Med Chem Lett 27: 4399-4404 (2017)
Article DOI: 10.1016/j.bmcl.2017.08.018
BindingDB Entry DOI: 10.7270/Q2W66P60 |
More data for this
Ligand-Target Pair | |
Cyclin-dependent kinase 5 activator 1
(Homo sapiens (Human)) | BDBM50261213
(CHEMBL4072013)Show SMILES Cc1cccc(n1)C(=O)N[C@H]1C[C@H](C1)n1cnc2c(NCC3CCNCC3)ncnc12 |r,wU:12.15,10.10,(35.5,-21.79,;34.42,-22.88,;32.93,-22.48,;31.84,-23.57,;32.24,-25.06,;33.72,-25.45,;34.81,-24.37,;34.13,-26.94,;35.63,-27.26,;33.1,-28.09,;31.59,-27.77,;30.29,-28.6,;29.46,-27.31,;30.75,-26.48,;27.95,-26.99,;27.32,-25.59,;25.79,-25.75,;25.47,-27.25,;24.14,-28.03,;22.81,-27.25,;21.47,-28.03,;20.14,-27.25,;20.14,-25.71,;18.81,-24.95,;17.48,-25.71,;17.48,-27.25,;18.81,-28.03,;24.14,-29.57,;25.47,-30.33,;26.81,-29.57,;26.81,-28.03,)| Show InChI InChI=1S/C22H28N8O/c1-14-3-2-4-18(28-14)22(31)29-16-9-17(10-16)30-13-27-19-20(25-12-26-21(19)30)24-11-15-5-7-23-8-6-15/h2-4,12-13,15-17,23H,5-11H2,1H3,(H,29,31)(H,24,25,26)/t16-,17+ | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 71 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology
Curated by ChEMBL
| Assay Description
Inhibition of CDK5/p35 (unknown origin) using ULingt-4E-BP as substrate after 1 hr in presence of ATP by fluorescence assay |
Bioorg Med Chem Lett 27: 4399-4404 (2017)
Article DOI: 10.1016/j.bmcl.2017.08.018
BindingDB Entry DOI: 10.7270/Q2W66P60 |
More data for this
Ligand-Target Pair | |
Cyclin-A2/Cyclin-dependent kinase 2
(Homo sapiens (Human)) | BDBM50261203
(CHEMBL4067461)Show SMILES Cc1cccc(n1)C(=O)N[C@H]1C[C@H](C1)n1cnc2c(NCc3ccc(Cl)c(Cl)c3)ncnc12 |r,wU:12.15,10.10,(32.81,-21.74,;31.71,-22.82,;30.22,-22.42,;29.14,-23.52,;29.54,-25,;31.02,-25.4,;32.11,-24.31,;31.42,-26.88,;32.93,-27.21,;30.39,-28.04,;28.88,-27.71,;27.59,-28.55,;26.76,-27.26,;28.05,-26.42,;25.25,-26.94,;24.62,-25.53,;23.09,-25.69,;22.77,-27.2,;21.44,-27.97,;20.1,-27.2,;18.77,-27.97,;17.44,-27.2,;17.44,-25.66,;16.1,-24.89,;14.77,-25.66,;13.43,-24.89,;14.77,-27.2,;13.43,-27.97,;16.1,-27.97,;21.44,-29.51,;22.77,-30.28,;24.1,-29.51,;24.1,-27.97,)| Show InChI InChI=1S/C23H21Cl2N7O/c1-13-3-2-4-19(30-13)23(33)31-15-8-16(9-15)32-12-29-20-21(27-11-28-22(20)32)26-10-14-5-6-17(24)18(25)7-14/h2-7,11-12,15-16H,8-10H2,1H3,(H,31,33)(H,26,27,28)/t15-,16+ | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 77 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology
Curated by ChEMBL
| Assay Description
Inhibition of CDK2/CyclinA (unknown origin) using ULingt-4E-BP as substrate after 1 hr in presence of ATP by fluorescence assay |
Bioorg Med Chem Lett 27: 4399-4404 (2017)
Article DOI: 10.1016/j.bmcl.2017.08.018
BindingDB Entry DOI: 10.7270/Q2W66P60 |
More data for this
Ligand-Target Pair | |
Cyclin-dependent kinase 5 activator 1
(Homo sapiens (Human)) | BDBM50261188
(CHEMBL4098980)Show SMILES Cc1cccc(n1)C(=O)N[C@H]1C[C@H](C1)n1cnc2c(NCC3CCN(CC3)C(=O)OC(C)(C)C)ncnc12 |r,wU:12.15,10.10,(33.46,-18.55,;32.37,-19.63,;30.88,-19.22,;29.79,-20.32,;30.18,-21.8,;31.67,-22.2,;32.76,-21.12,;32.06,-23.69,;33.56,-24.01,;31.02,-24.84,;29.51,-24.51,;28.22,-25.33,;27.39,-24.04,;28.69,-23.22,;25.88,-23.71,;25.26,-22.31,;23.73,-22.46,;23.4,-23.97,;22.07,-24.74,;20.74,-23.96,;19.41,-24.73,;18.07,-23.95,;18.08,-22.41,;16.75,-21.64,;15.41,-22.4,;15.41,-23.94,;16.73,-24.72,;14.08,-21.63,;14.09,-20.09,;12.74,-22.39,;11.41,-21.62,;10.08,-20.84,;11.42,-20.09,;10.08,-22.38,;22.06,-26.28,;23.39,-27.05,;24.73,-26.29,;24.74,-24.75,)| Show InChI InChI=1S/C27H36N8O3/c1-17-6-5-7-21(32-17)25(36)33-19-12-20(13-19)35-16-31-22-23(29-15-30-24(22)35)28-14-18-8-10-34(11-9-18)26(37)38-27(2,3)4/h5-7,15-16,18-20H,8-14H2,1-4H3,(H,33,36)(H,28,29,30)/t19-,20+ | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 90 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology
Curated by ChEMBL
| Assay Description
Inhibition of CDK5/p35 (unknown origin) using ULingt-4E-BP as substrate after 1 hr in presence of ATP by fluorescence assay |
Bioorg Med Chem Lett 27: 4399-4404 (2017)
Article DOI: 10.1016/j.bmcl.2017.08.018
BindingDB Entry DOI: 10.7270/Q2W66P60 |
More data for this
Ligand-Target Pair | |
Cyclin-dependent kinase 5 activator 1
(Homo sapiens (Human)) | BDBM50261198
(CHEMBL4091242)Show SMILES COc1ccc(Nc2ncnc3n(cnc23)[C@@H]2C[C@@H](C2)NC(=O)c2cccc(C)n2)cc1OC |r,wU:16.17,18.22,(11.31,-24.61,;12.65,-25.37,;13.98,-24.58,;13.97,-23.04,;15.29,-22.27,;16.63,-23.02,;17.96,-22.24,;19.3,-22.99,;19.32,-24.53,;20.66,-25.29,;21.98,-24.5,;21.96,-22.96,;23.1,-21.92,;22.46,-20.52,;20.93,-20.7,;20.62,-22.21,;24.61,-22.23,;25.46,-23.51,;26.74,-22.66,;25.9,-21.38,;28.25,-22.96,;29.28,-21.81,;30.79,-22.12,;28.86,-20.33,;27.37,-19.94,;26.95,-18.46,;28.03,-17.36,;29.52,-17.75,;30.61,-16.65,;29.94,-19.23,;16.65,-24.56,;15.33,-25.34,;15.34,-26.89,;14.02,-27.66,)| Show InChI InChI=1S/C24H25N7O3/c1-14-5-4-6-18(28-14)24(32)30-16-9-17(10-16)31-13-27-21-22(25-12-26-23(21)31)29-15-7-8-19(33-2)20(11-15)34-3/h4-8,11-13,16-17H,9-10H2,1-3H3,(H,30,32)(H,25,26,29)/t16-,17+ | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Patents
| Article
PubMed
| n/a | n/a | 94 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology
Curated by ChEMBL
| Assay Description
Inhibition of CDK5/p35 (unknown origin) using ULingt-4E-BP as substrate after 1 hr in presence of ATP by fluorescence assay |
Bioorg Med Chem Lett 27: 4399-4404 (2017)
Article DOI: 10.1016/j.bmcl.2017.08.018
BindingDB Entry DOI: 10.7270/Q2W66P60 |
More data for this
Ligand-Target Pair | |
Cyclin-A2/Cyclin-dependent kinase 2
(Homo sapiens (Human)) | BDBM50261187
(CHEMBL4082490)Show SMILES Cc1cccc(n1)C(=O)N[C@H]1C[C@H](C1)n1cnc2c(NC3CCN(CC3)C(=O)OC(C)(C)C)ncnc12 |r,wU:10.10,12.15,(35.5,-22.63,;34.42,-23.72,;32.93,-23.33,;31.84,-24.42,;32.24,-25.9,;33.73,-26.3,;34.82,-25.21,;34.13,-27.79,;35.63,-28.1,;33.1,-28.93,;31.59,-28.61,;30.31,-29.46,;29.46,-28.16,;30.75,-27.33,;27.95,-27.85,;27.33,-26.44,;25.8,-26.6,;25.48,-28.11,;24.15,-28.88,;22.81,-28.11,;21.47,-28.89,;20.14,-28.12,;18.81,-28.89,;18.81,-30.43,;20.14,-31.2,;21.48,-30.43,;17.48,-31.2,;16.15,-30.44,;17.48,-32.74,;16.15,-33.52,;16.16,-35.05,;14.82,-32.76,;14.81,-34.27,;24.15,-30.42,;25.48,-31.19,;26.82,-30.42,;26.81,-28.88,)| Show InChI InChI=1S/C26H34N8O3/c1-16-6-5-7-20(30-16)24(35)32-18-12-19(13-18)34-15-29-21-22(27-14-28-23(21)34)31-17-8-10-33(11-9-17)25(36)37-26(2,3)4/h5-7,14-15,17-19H,8-13H2,1-4H3,(H,32,35)(H,27,28,31)/t18-,19+ | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Patents
Similars
| Article
PubMed
| n/a | n/a | 95 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology
Curated by ChEMBL
| Assay Description
Inhibition of CDK2/CyclinA (unknown origin) using ULingt-4E-BP as substrate after 1 hr in presence of ATP by fluorescence assay |
Bioorg Med Chem Lett 27: 4399-4404 (2017)
Article DOI: 10.1016/j.bmcl.2017.08.018
BindingDB Entry DOI: 10.7270/Q2W66P60 |
More data for this
Ligand-Target Pair | |
Cyclin-A2/Cyclin-dependent kinase 2
(Homo sapiens (Human)) | BDBM50261170
(CHEMBL4092920)Show SMILES CC(=O)N[C@H]1CC[C@H](CC1)Nc1ncnc2n(cnc12)[C@@H]1C[C@@H](C1)NC(=O)c1cccc(C)n1 |r,wU:4.3,7.10,20.22,22.27,(16.83,-30.61,;16.84,-32.15,;15.51,-32.93,;18.17,-32.92,;19.5,-32.14,;19.5,-30.6,;20.83,-29.83,;22.16,-30.59,;22.17,-32.13,;20.84,-32.91,;23.5,-29.82,;24.83,-30.58,;24.84,-32.12,;26.18,-32.88,;27.5,-32.11,;27.5,-30.57,;28.64,-29.53,;28.01,-28.13,;26.48,-28.3,;26.16,-29.8,;30.14,-29.85,;30.99,-31.14,;32.28,-30.29,;31.43,-29,;33.79,-30.6,;34.81,-29.46,;36.32,-29.77,;34.4,-27.97,;32.91,-27.58,;32.52,-26.09,;33.6,-25,;35.09,-25.39,;36.17,-24.3,;35.49,-26.87,)| Show InChI InChI=1S/C24H30N8O2/c1-14-4-3-5-20(28-14)24(34)31-18-10-19(11-18)32-13-27-21-22(25-12-26-23(21)32)30-17-8-6-16(7-9-17)29-15(2)33/h3-5,12-13,16-19H,6-11H2,1-2H3,(H,29,33)(H,31,34)(H,25,26,30)/t16-,17+,18-,19+ | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 112 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology
Curated by ChEMBL
| Assay Description
Inhibition of CDK2/CyclinA (unknown origin) using ULingt-4E-BP as substrate after 1 hr in presence of ATP by fluorescence assay |
Bioorg Med Chem Lett 27: 4399-4404 (2017)
Article DOI: 10.1016/j.bmcl.2017.08.018
BindingDB Entry DOI: 10.7270/Q2W66P60 |
More data for this
Ligand-Target Pair | |
Cyclin-A2/Cyclin-dependent kinase 2
(Homo sapiens (Human)) | BDBM50261169
(CHEMBL4076545)Show SMILES CC(=O)N[C@H]1CC[C@@H](CC1)Nc1ncnc2n(cnc12)[C@@H]1C[C@@H](C1)NC(=O)c1cccc(C)n1 |r,wU:7.10,20.22,22.27,wD:4.3,(16.83,-30.61,;16.84,-32.15,;15.51,-32.93,;18.17,-32.92,;19.5,-32.14,;20.84,-32.91,;22.17,-32.13,;22.16,-30.59,;20.83,-29.83,;19.5,-30.6,;23.5,-29.82,;24.83,-30.58,;24.84,-32.12,;26.18,-32.88,;27.5,-32.11,;27.5,-30.57,;28.64,-29.53,;28.01,-28.13,;26.48,-28.3,;26.16,-29.8,;30.14,-29.85,;30.99,-31.14,;32.28,-30.29,;31.43,-29,;33.79,-30.6,;34.81,-29.46,;36.32,-29.77,;34.4,-27.97,;32.91,-27.58,;32.52,-26.09,;33.6,-25,;35.09,-25.39,;36.17,-24.3,;35.49,-26.87,)| Show InChI InChI=1S/C24H30N8O2/c1-14-4-3-5-20(28-14)24(34)31-18-10-19(11-18)32-13-27-21-22(25-12-26-23(21)32)30-17-8-6-16(7-9-17)29-15(2)33/h3-5,12-13,16-19H,6-11H2,1-2H3,(H,29,33)(H,31,34)(H,25,26,30)/t16-,17-,18-,19+ | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 160 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology
Curated by ChEMBL
| Assay Description
Inhibition of CDK2/CyclinA (unknown origin) using ULingt-4E-BP as substrate after 1 hr in presence of ATP by fluorescence assay |
Bioorg Med Chem Lett 27: 4399-4404 (2017)
Article DOI: 10.1016/j.bmcl.2017.08.018
BindingDB Entry DOI: 10.7270/Q2W66P60 |
More data for this
Ligand-Target Pair | |
Cyclin-dependent kinase 5 activator 1
(Homo sapiens (Human)) | BDBM50261186
(CHEMBL4059822)Show SMILES Cc1cccc(n1)C(=O)N[C@H]1C[C@H](C1)n1cnc2c(NC3CCNCC3)ncnc12 |r,wU:12.15,10.10,(29.95,-17.13,;28.87,-18.21,;27.38,-17.81,;26.3,-18.91,;26.7,-20.4,;28.18,-20.79,;29.27,-19.7,;28.58,-22.27,;30.08,-22.6,;27.55,-23.43,;26.04,-23.1,;24.75,-23.94,;23.91,-22.65,;25.2,-21.81,;22.41,-22.33,;21.78,-20.92,;20.25,-21.09,;19.93,-22.59,;18.6,-23.37,;17.27,-22.59,;15.93,-23.37,;14.59,-22.59,;13.26,-23.37,;13.26,-24.91,;14.6,-25.67,;15.93,-24.91,;18.6,-24.91,;19.93,-25.67,;21.26,-24.91,;21.26,-23.37,)| Show InChI InChI=1S/C21H26N8O/c1-13-3-2-4-17(26-13)21(30)28-15-9-16(10-15)29-12-25-18-19(23-11-24-20(18)29)27-14-5-7-22-8-6-14/h2-4,11-12,14-16,22H,5-10H2,1H3,(H,28,30)(H,23,24,27)/t15-,16+ | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Patents
| Article
PubMed
| n/a | n/a | 162 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology
Curated by ChEMBL
| Assay Description
Inhibition of CDK5/p35 (unknown origin) using ULingt-4E-BP as substrate after 1 hr in presence of ATP by fluorescence assay |
Bioorg Med Chem Lett 27: 4399-4404 (2017)
Article DOI: 10.1016/j.bmcl.2017.08.018
BindingDB Entry DOI: 10.7270/Q2W66P60 |
More data for this
Ligand-Target Pair | |
Cyclin-dependent kinase 5 activator 1
(Homo sapiens (Human)) | BDBM50261210
(CHEMBL4104979)Show SMILES CC(=O)N1CCC(CC1)Nc1ncnc2n(cnc12)[C@@H]1C[C@@H](C1)NC(=O)c1cccc(C)n1 |r,wU:19.21,21.26,(17.13,-19.64,;18.45,-20.43,;18.43,-21.97,;19.8,-19.68,;21.12,-20.47,;22.46,-19.73,;22.49,-18.19,;21.17,-17.39,;19.82,-18.14,;23.84,-17.44,;25.16,-18.23,;25.13,-19.77,;26.45,-20.56,;27.8,-19.82,;27.82,-18.28,;28.99,-17.27,;28.38,-15.85,;26.85,-15.98,;26.5,-17.48,;30.49,-17.61,;31.3,-18.92,;32.61,-18.1,;31.79,-16.79,;34.11,-18.45,;35.16,-17.32,;36.66,-17.66,;34.79,-15.83,;33.31,-15.4,;32.93,-13.91,;34.04,-12.84,;35.52,-13.26,;36.63,-12.19,;35.89,-14.75,)| Show InChI InChI=1S/C23H28N8O2/c1-14-4-3-5-19(27-14)23(33)29-17-10-18(11-17)31-13-26-20-21(24-12-25-22(20)31)28-16-6-8-30(9-7-16)15(2)32/h3-5,12-13,16-18H,6-11H2,1-2H3,(H,29,33)(H,24,25,28)/t17-,18+ | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 179 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology
Curated by ChEMBL
| Assay Description
Inhibition of CDK5/p35 (unknown origin) using ULingt-4E-BP as substrate after 1 hr in presence of ATP by fluorescence assay |
Bioorg Med Chem Lett 27: 4399-4404 (2017)
Article DOI: 10.1016/j.bmcl.2017.08.018
BindingDB Entry DOI: 10.7270/Q2W66P60 |
More data for this
Ligand-Target Pair | |
CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7
(Homo sapiens (Human)) | BDBM50261164
(CHEMBL4103221)Show SMILES Cc1cccc(n1)C(=O)N[C@H]1C[C@H](C1)n1cnc2c(NCc3cccc(Cl)c3)ncnc12 |r,wU:12.15,10.10,(26.01,-22.02,;24.92,-23.11,;23.43,-22.71,;22.35,-23.8,;22.75,-25.29,;24.23,-25.68,;25.32,-24.6,;24.63,-27.17,;26.14,-27.49,;23.6,-28.32,;22.09,-28,;20.8,-28.83,;19.97,-27.54,;21.26,-26.71,;18.46,-27.22,;17.83,-25.81,;16.3,-25.98,;15.98,-27.48,;14.65,-28.26,;13.31,-27.48,;11.98,-28.26,;10.65,-27.48,;10.65,-25.94,;9.31,-25.18,;7.98,-25.94,;7.98,-27.48,;6.64,-28.26,;9.31,-28.26,;14.65,-29.8,;15.98,-30.56,;17.31,-29.8,;17.31,-28.26,)| Show InChI InChI=1S/C23H22ClN7O/c1-14-4-2-7-19(29-14)23(32)30-17-9-18(10-17)31-13-28-20-21(26-12-27-22(20)31)25-11-15-5-3-6-16(24)8-15/h2-8,12-13,17-18H,9-11H2,1H3,(H,30,32)(H,25,26,27)/t17-,18+ | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 319 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology
Curated by ChEMBL
| Assay Description
Inhibition of human CDK7/CyclinH/MAT1 |
Bioorg Med Chem Lett 27: 4399-4404 (2017)
Article DOI: 10.1016/j.bmcl.2017.08.018
BindingDB Entry DOI: 10.7270/Q2W66P60 |
More data for this
Ligand-Target Pair | |
CDK-activating kinase assembly factor MAT1/Cyclin-H/Cyclin-dependent kinase 7
(Homo sapiens (Human)) | BDBM50261163
(CHEMBL4081756)Show SMILES Cc1cccc(n1)C(=O)N[C@H]1C[C@H](C1)n1cnc2c(NCc3cccc(Br)c3)ncnc12 |r,wU:12.15,10.10,(36.41,-23.55,;35.32,-24.63,;33.83,-24.23,;32.74,-25.33,;33.14,-26.81,;34.63,-27.21,;35.72,-26.12,;35.02,-28.69,;36.54,-29.01,;33.99,-29.84,;32.49,-29.52,;31.2,-30.36,;30.36,-29.07,;31.65,-28.23,;28.86,-28.74,;28.23,-27.34,;26.7,-27.5,;26.37,-29.01,;25.04,-29.78,;23.71,-29.01,;22.38,-29.78,;21.04,-29.01,;21.04,-27.47,;19.7,-26.7,;18.37,-27.47,;18.37,-29.01,;17.04,-29.78,;19.7,-29.78,;25.04,-31.32,;26.37,-32.09,;27.71,-31.32,;27.71,-29.78,)| Show InChI InChI=1S/C23H22BrN7O/c1-14-4-2-7-19(29-14)23(32)30-17-9-18(10-17)31-13-28-20-21(26-12-27-22(20)31)25-11-15-5-3-6-16(24)8-15/h2-8,12-13,17-18H,9-11H2,1H3,(H,30,32)(H,25,26,27)/t17-,18+ | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 359 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology
Curated by ChEMBL
| Assay Description
Inhibition of human CDK7/CyclinH/MAT1 |
Bioorg Med Chem Lett 27: 4399-4404 (2017)
Article DOI: 10.1016/j.bmcl.2017.08.018
BindingDB Entry DOI: 10.7270/Q2W66P60 |
More data for this
Ligand-Target Pair | |
Cyclin-A2/Cyclin-dependent kinase 2
(Homo sapiens (Human)) | BDBM50261188
(CHEMBL4098980)Show SMILES Cc1cccc(n1)C(=O)N[C@H]1C[C@H](C1)n1cnc2c(NCC3CCN(CC3)C(=O)OC(C)(C)C)ncnc12 |r,wU:12.15,10.10,(33.46,-18.55,;32.37,-19.63,;30.88,-19.22,;29.79,-20.32,;30.18,-21.8,;31.67,-22.2,;32.76,-21.12,;32.06,-23.69,;33.56,-24.01,;31.02,-24.84,;29.51,-24.51,;28.22,-25.33,;27.39,-24.04,;28.69,-23.22,;25.88,-23.71,;25.26,-22.31,;23.73,-22.46,;23.4,-23.97,;22.07,-24.74,;20.74,-23.96,;19.41,-24.73,;18.07,-23.95,;18.08,-22.41,;16.75,-21.64,;15.41,-22.4,;15.41,-23.94,;16.73,-24.72,;14.08,-21.63,;14.09,-20.09,;12.74,-22.39,;11.41,-21.62,;10.08,-20.84,;11.42,-20.09,;10.08,-22.38,;22.06,-26.28,;23.39,-27.05,;24.73,-26.29,;24.74,-24.75,)| Show InChI InChI=1S/C27H36N8O3/c1-17-6-5-7-21(32-17)25(36)33-19-12-20(13-19)35-16-31-22-23(29-15-30-24(22)35)28-14-18-8-10-34(11-9-18)26(37)38-27(2,3)4/h5-7,15-16,18-20H,8-14H2,1-4H3,(H,33,36)(H,28,29,30)/t19-,20+ | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 376 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology
Curated by ChEMBL
| Assay Description
Inhibition of CDK2/CyclinA (unknown origin) using ULingt-4E-BP as substrate after 1 hr in presence of ATP by fluorescence assay |
Bioorg Med Chem Lett 27: 4399-4404 (2017)
Article DOI: 10.1016/j.bmcl.2017.08.018
BindingDB Entry DOI: 10.7270/Q2W66P60 |
More data for this
Ligand-Target Pair | |
Cyclin-A2/Cyclin-dependent kinase 2
(Homo sapiens (Human)) | BDBM50261186
(CHEMBL4059822)Show SMILES Cc1cccc(n1)C(=O)N[C@H]1C[C@H](C1)n1cnc2c(NC3CCNCC3)ncnc12 |r,wU:12.15,10.10,(29.95,-17.13,;28.87,-18.21,;27.38,-17.81,;26.3,-18.91,;26.7,-20.4,;28.18,-20.79,;29.27,-19.7,;28.58,-22.27,;30.08,-22.6,;27.55,-23.43,;26.04,-23.1,;24.75,-23.94,;23.91,-22.65,;25.2,-21.81,;22.41,-22.33,;21.78,-20.92,;20.25,-21.09,;19.93,-22.59,;18.6,-23.37,;17.27,-22.59,;15.93,-23.37,;14.59,-22.59,;13.26,-23.37,;13.26,-24.91,;14.6,-25.67,;15.93,-24.91,;18.6,-24.91,;19.93,-25.67,;21.26,-24.91,;21.26,-23.37,)| Show InChI InChI=1S/C21H26N8O/c1-13-3-2-4-17(26-13)21(30)28-15-9-16(10-15)29-12-25-18-19(23-11-24-20(18)29)27-14-5-7-22-8-6-14/h2-4,11-12,14-16,22H,5-10H2,1H3,(H,28,30)(H,23,24,27)/t15-,16+ | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Patents
| Article
PubMed
| n/a | n/a | 379 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology
Curated by ChEMBL
| Assay Description
Inhibition of CDK2/CyclinA (unknown origin) using ULingt-4E-BP as substrate after 1 hr in presence of ATP by fluorescence assay |
Bioorg Med Chem Lett 27: 4399-4404 (2017)
Article DOI: 10.1016/j.bmcl.2017.08.018
BindingDB Entry DOI: 10.7270/Q2W66P60 |
More data for this
Ligand-Target Pair | |
Cyclin-A2/Cyclin-dependent kinase 2
(Homo sapiens (Human)) | BDBM50261210
(CHEMBL4104979)Show SMILES CC(=O)N1CCC(CC1)Nc1ncnc2n(cnc12)[C@@H]1C[C@@H](C1)NC(=O)c1cccc(C)n1 |r,wU:19.21,21.26,(17.13,-19.64,;18.45,-20.43,;18.43,-21.97,;19.8,-19.68,;21.12,-20.47,;22.46,-19.73,;22.49,-18.19,;21.17,-17.39,;19.82,-18.14,;23.84,-17.44,;25.16,-18.23,;25.13,-19.77,;26.45,-20.56,;27.8,-19.82,;27.82,-18.28,;28.99,-17.27,;28.38,-15.85,;26.85,-15.98,;26.5,-17.48,;30.49,-17.61,;31.3,-18.92,;32.61,-18.1,;31.79,-16.79,;34.11,-18.45,;35.16,-17.32,;36.66,-17.66,;34.79,-15.83,;33.31,-15.4,;32.93,-13.91,;34.04,-12.84,;35.52,-13.26,;36.63,-12.19,;35.89,-14.75,)| Show InChI InChI=1S/C23H28N8O2/c1-14-4-3-5-19(27-14)23(33)29-17-10-18(11-17)31-13-26-20-21(24-12-25-22(20)31)28-16-6-8-30(9-7-16)15(2)32/h3-5,12-13,16-18H,6-11H2,1-2H3,(H,29,33)(H,24,25,28)/t17-,18+ | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 474 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology
Curated by ChEMBL
| Assay Description
Inhibition of CDK2/CyclinA (unknown origin) using ULingt-4E-BP as substrate after 1 hr in presence of ATP by fluorescence assay |
Bioorg Med Chem Lett 27: 4399-4404 (2017)
Article DOI: 10.1016/j.bmcl.2017.08.018
BindingDB Entry DOI: 10.7270/Q2W66P60 |
More data for this
Ligand-Target Pair | |
Cyclin-dependent kinase 5 activator 1
(Homo sapiens (Human)) | BDBM50261172
(CHEMBL4087130)Show SMILES Cc1cccc(n1)C(=O)N[C@H]1C[C@H](C1)n1cnc2c(N[C@H]3CC[C@H](O)CC3)ncnc12 |r,wU:20.21,12.15,10.10,wD:23.25,(39.8,-22.66,;38.72,-23.75,;37.23,-23.36,;36.15,-24.46,;36.56,-25.95,;38.05,-26.34,;39.13,-25.24,;38.46,-27.82,;39.97,-28.13,;37.44,-28.97,;35.93,-28.66,;34.64,-29.5,;33.79,-28.22,;35.08,-27.38,;32.29,-27.91,;31.65,-26.51,;30.12,-26.68,;29.81,-28.19,;28.48,-28.97,;27.14,-28.2,;25.81,-28.99,;25.82,-30.53,;24.5,-31.3,;23.16,-30.54,;21.83,-31.32,;23.15,-29,;24.48,-28.22,;28.49,-30.51,;29.83,-31.27,;31.16,-30.49,;31.15,-28.95,)| Show InChI InChI=1S/C22H27N7O2/c1-13-3-2-4-18(26-13)22(31)28-15-9-16(10-15)29-12-25-19-20(23-11-24-21(19)29)27-14-5-7-17(30)8-6-14/h2-4,11-12,14-17,30H,5-10H2,1H3,(H,28,31)(H,23,24,27)/t14-,15-,16+,17- | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >500 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology
Curated by ChEMBL
| Assay Description
Inhibition of CDK5/p35 (unknown origin) using ULingt-4E-BP as substrate after 1 hr in presence of ATP by fluorescence assay |
Bioorg Med Chem Lett 27: 4399-4404 (2017)
Article DOI: 10.1016/j.bmcl.2017.08.018
BindingDB Entry DOI: 10.7270/Q2W66P60 |
More data for this
Ligand-Target Pair | |
Cyclin-dependent kinase 5 activator 1
(Homo sapiens (Human)) | BDBM50261171
(CHEMBL4097273)Show SMILES Cc1cccc(n1)C(=O)N[C@H]1C[C@H](C1)n1cnc2c(NC3CCN(C3)C(=O)OC(C)(C)C)ncnc12 |r,wU:10.10,12.15,(31.06,-13.58,;29.98,-14.67,;28.49,-14.27,;27.4,-15.36,;27.8,-16.85,;29.28,-17.25,;30.37,-16.15,;29.68,-18.73,;31.19,-19.05,;28.65,-19.88,;27.14,-19.55,;25.85,-20.4,;25.02,-19.1,;26.31,-18.26,;23.51,-18.79,;22.88,-17.38,;21.35,-17.53,;21.03,-19.04,;19.7,-19.81,;18.36,-19.04,;17.03,-19.81,;16.87,-21.34,;15.36,-21.67,;14.6,-20.33,;15.63,-19.18,;13.07,-20.17,;12.44,-18.77,;12.16,-21.42,;10.63,-21.25,;9.73,-22.49,;10.01,-19.85,;9.1,-21.24,;19.7,-21.35,;21.03,-22.12,;22.37,-21.35,;22.37,-19.81,)| Show InChI InChI=1S/C25H32N8O3/c1-15-6-5-7-19(29-15)23(34)31-17-10-18(11-17)33-14-28-20-21(26-13-27-22(20)33)30-16-8-9-32(12-16)24(35)36-25(2,3)4/h5-7,13-14,16-18H,8-12H2,1-4H3,(H,31,34)(H,26,27,30)/t16?,17-,18+ | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >500 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology
Curated by ChEMBL
| Assay Description
Inhibition of CDK5/p35 (unknown origin) using ULingt-4E-BP as substrate after 1 hr in presence of ATP by fluorescence assay |
Bioorg Med Chem Lett 27: 4399-4404 (2017)
Article DOI: 10.1016/j.bmcl.2017.08.018
BindingDB Entry DOI: 10.7270/Q2W66P60 |
More data for this
Ligand-Target Pair | |
Cyclin-dependent kinase 4/G1/S-specific cyclin-D3
(Homo sapiens (Human)) | BDBM50261163
(CHEMBL4081756)Show SMILES Cc1cccc(n1)C(=O)N[C@H]1C[C@H](C1)n1cnc2c(NCc3cccc(Br)c3)ncnc12 |r,wU:12.15,10.10,(36.41,-23.55,;35.32,-24.63,;33.83,-24.23,;32.74,-25.33,;33.14,-26.81,;34.63,-27.21,;35.72,-26.12,;35.02,-28.69,;36.54,-29.01,;33.99,-29.84,;32.49,-29.52,;31.2,-30.36,;30.36,-29.07,;31.65,-28.23,;28.86,-28.74,;28.23,-27.34,;26.7,-27.5,;26.37,-29.01,;25.04,-29.78,;23.71,-29.01,;22.38,-29.78,;21.04,-29.01,;21.04,-27.47,;19.7,-26.7,;18.37,-27.47,;18.37,-29.01,;17.04,-29.78,;19.7,-29.78,;25.04,-31.32,;26.37,-32.09,;27.71,-31.32,;27.71,-29.78,)| Show InChI InChI=1S/C23H22BrN7O/c1-14-4-2-7-19(29-14)23(32)30-17-9-18(10-17)31-13-28-20-21(26-12-27-22(20)31)25-11-15-5-3-6-16(24)8-15/h2-8,12-13,17-18H,9-11H2,1H3,(H,30,32)(H,25,26,27)/t17-,18+ | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 611 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology
Curated by ChEMBL
| Assay Description
Inhibition of human CDK4/CyclinD3 |
Bioorg Med Chem Lett 27: 4399-4404 (2017)
Article DOI: 10.1016/j.bmcl.2017.08.018
BindingDB Entry DOI: 10.7270/Q2W66P60 |
More data for this
Ligand-Target Pair | |
Cyclin-dependent kinase 5 activator 1
(Homo sapiens (Human)) | BDBM50261201
(CHEMBL4101443)Show SMILES Cc1cccc(n1)C(=O)N[C@H]1C[C@H](C1)n1cnc2c(Nc3ccncc3)ncnc12 |r,wU:12.15,10.10,(34.42,-23.86,;33.3,-24.92,;31.82,-24.49,;30.71,-25.56,;31.08,-27.06,;32.56,-27.48,;33.67,-26.42,;32.92,-28.98,;34.42,-29.33,;31.87,-30.11,;30.37,-29.75,;29.06,-30.56,;28.25,-29.25,;29.56,-28.44,;26.75,-28.9,;26.15,-27.48,;24.62,-27.61,;24.26,-29.1,;22.92,-29.85,;21.6,-29.05,;20.25,-29.79,;18.94,-28.99,;17.59,-29.73,;17.55,-31.27,;18.87,-32.07,;20.22,-31.33,;22.88,-31.39,;24.2,-32.18,;25.55,-31.45,;25.58,-29.91,)| Show InChI InChI=1S/C21H20N8O/c1-13-3-2-4-17(26-13)21(30)28-15-9-16(10-15)29-12-25-18-19(23-11-24-20(18)29)27-14-5-7-22-8-6-14/h2-8,11-12,15-16H,9-10H2,1H3,(H,28,30)(H,22,23,24,27)/t15-,16+ | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology
Curated by ChEMBL
| Assay Description
Inhibition of CDK5/p35 (unknown origin) using ULingt-4E-BP as substrate after 1 hr in presence of ATP by fluorescence assay |
Bioorg Med Chem Lett 27: 4399-4404 (2017)
Article DOI: 10.1016/j.bmcl.2017.08.018
BindingDB Entry DOI: 10.7270/Q2W66P60 |
More data for this
Ligand-Target Pair | |
Cyclin-dependent kinase 4/G1/S-specific cyclin-D3
(Homo sapiens (Human)) | BDBM50261164
(CHEMBL4103221)Show SMILES Cc1cccc(n1)C(=O)N[C@H]1C[C@H](C1)n1cnc2c(NCc3cccc(Cl)c3)ncnc12 |r,wU:12.15,10.10,(26.01,-22.02,;24.92,-23.11,;23.43,-22.71,;22.35,-23.8,;22.75,-25.29,;24.23,-25.68,;25.32,-24.6,;24.63,-27.17,;26.14,-27.49,;23.6,-28.32,;22.09,-28,;20.8,-28.83,;19.97,-27.54,;21.26,-26.71,;18.46,-27.22,;17.83,-25.81,;16.3,-25.98,;15.98,-27.48,;14.65,-28.26,;13.31,-27.48,;11.98,-28.26,;10.65,-27.48,;10.65,-25.94,;9.31,-25.18,;7.98,-25.94,;7.98,-27.48,;6.64,-28.26,;9.31,-28.26,;14.65,-29.8,;15.98,-30.56,;17.31,-29.8,;17.31,-28.26,)| Show InChI InChI=1S/C23H22ClN7O/c1-14-4-2-7-19(29-14)23(32)30-17-9-18(10-17)31-13-28-20-21(26-12-27-22(20)31)25-11-15-5-3-6-16(24)8-15/h2-8,12-13,17-18H,9-11H2,1H3,(H,30,32)(H,25,26,27)/t17-,18+ | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology
Curated by ChEMBL
| Assay Description
Inhibition of human CDK4/CyclinD3 |
Bioorg Med Chem Lett 27: 4399-4404 (2017)
Article DOI: 10.1016/j.bmcl.2017.08.018
BindingDB Entry DOI: 10.7270/Q2W66P60 |
More data for this
Ligand-Target Pair | |
Cyclin-A2/Cyclin-dependent kinase 2
(Homo sapiens (Human)) | BDBM50261201
(CHEMBL4101443)Show SMILES Cc1cccc(n1)C(=O)N[C@H]1C[C@H](C1)n1cnc2c(Nc3ccncc3)ncnc12 |r,wU:12.15,10.10,(34.42,-23.86,;33.3,-24.92,;31.82,-24.49,;30.71,-25.56,;31.08,-27.06,;32.56,-27.48,;33.67,-26.42,;32.92,-28.98,;34.42,-29.33,;31.87,-30.11,;30.37,-29.75,;29.06,-30.56,;28.25,-29.25,;29.56,-28.44,;26.75,-28.9,;26.15,-27.48,;24.62,-27.61,;24.26,-29.1,;22.92,-29.85,;21.6,-29.05,;20.25,-29.79,;18.94,-28.99,;17.59,-29.73,;17.55,-31.27,;18.87,-32.07,;20.22,-31.33,;22.88,-31.39,;24.2,-32.18,;25.55,-31.45,;25.58,-29.91,)| Show InChI InChI=1S/C21H20N8O/c1-13-3-2-4-17(26-13)21(30)28-15-9-16(10-15)29-12-25-18-19(23-11-24-20(18)29)27-14-5-7-22-8-6-14/h2-8,11-12,15-16H,9-10H2,1H3,(H,28,30)(H,22,23,24,27)/t15-,16+ | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology
Curated by ChEMBL
| Assay Description
Inhibition of CDK2/CyclinA (unknown origin) using ULingt-4E-BP as substrate after 1 hr in presence of ATP by fluorescence assay |
Bioorg Med Chem Lett 27: 4399-4404 (2017)
Article DOI: 10.1016/j.bmcl.2017.08.018
BindingDB Entry DOI: 10.7270/Q2W66P60 |
More data for this
Ligand-Target Pair | |
Cyclin-dependent kinase 5 activator 1
(Homo sapiens (Human)) | BDBM50261214
(CHEMBL4070922)Show SMILES Cc1cccc(n1)C(=O)N[C@H]1C[C@H](C1)n1cnc2c(NC3CCNC3)ncnc12 |r,wU:12.15,10.10,(32.35,-16.29,;31.27,-17.39,;29.78,-17.01,;28.71,-18.12,;29.13,-19.61,;30.62,-19.98,;31.69,-18.88,;31.04,-21.46,;32.55,-21.76,;30.02,-22.62,;28.51,-22.32,;27.24,-23.18,;26.37,-21.9,;27.66,-21.04,;24.86,-21.6,;24.22,-20.2,;22.69,-20.38,;22.39,-21.89,;21.07,-22.69,;19.73,-21.93,;18.41,-22.72,;18.27,-24.26,;16.77,-24.59,;15.97,-23.27,;16.99,-22.11,;21.09,-24.22,;22.44,-24.97,;23.76,-24.19,;23.74,-22.65,)| Show InChI InChI=1S/C20H24N8O/c1-12-3-2-4-16(25-12)20(29)27-14-7-15(8-14)28-11-24-17-18(22-10-23-19(17)28)26-13-5-6-21-9-13/h2-4,10-11,13-15,21H,5-9H2,1H3,(H,27,29)(H,22,23,26)/t13?,14-,15+ | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology
Curated by ChEMBL
| Assay Description
Inhibition of CDK5/p35 (unknown origin) using ULingt-4E-BP as substrate after 1 hr in presence of ATP by fluorescence assay |
Bioorg Med Chem Lett 27: 4399-4404 (2017)
Article DOI: 10.1016/j.bmcl.2017.08.018
BindingDB Entry DOI: 10.7270/Q2W66P60 |
More data for this
Ligand-Target Pair | |
Cyclin-dependent kinase 5 activator 1
(Homo sapiens (Human)) | BDBM50261185
(CHEMBL4082514)Show SMILES CN1CCC(CC1)Nc1ncnc2n(cnc12)[C@@H]1C[C@@H](C1)NC(=O)c1cccc(C)n1 |r,wU:17.19,19.24,(14.11,-34.93,;15.44,-34.17,;15.44,-32.63,;16.77,-31.85,;18.1,-32.63,;18.1,-34.17,;16.77,-34.93,;19.44,-31.85,;20.78,-32.63,;20.78,-34.17,;22.11,-34.94,;23.44,-34.17,;23.44,-32.63,;24.59,-31.6,;23.96,-30.19,;22.43,-30.35,;22.11,-31.86,;26.09,-31.92,;26.93,-33.21,;28.22,-32.38,;27.38,-31.08,;29.73,-32.7,;30.76,-31.55,;32.26,-31.87,;30.36,-30.06,;28.87,-29.67,;28.48,-28.18,;29.57,-27.09,;31.05,-27.49,;32.14,-26.4,;31.45,-28.98,)| Show InChI InChI=1S/C22H28N8O/c1-14-4-3-5-18(26-14)22(31)28-16-10-17(11-16)30-13-25-19-20(23-12-24-21(19)30)27-15-6-8-29(2)9-7-15/h3-5,12-13,15-17H,6-11H2,1-2H3,(H,28,31)(H,23,24,27)/t16-,17+ | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology
Curated by ChEMBL
| Assay Description
Inhibition of CDK5/p35 (unknown origin) using ULingt-4E-BP as substrate after 1 hr in presence of ATP by fluorescence assay |
Bioorg Med Chem Lett 27: 4399-4404 (2017)
Article DOI: 10.1016/j.bmcl.2017.08.018
BindingDB Entry DOI: 10.7270/Q2W66P60 |
More data for this
Ligand-Target Pair | |
Cyclin-dependent kinase 6/G1/S-specific cyclin-D3
(Homo sapiens (Human)) | BDBM50261163
(CHEMBL4081756)Show SMILES Cc1cccc(n1)C(=O)N[C@H]1C[C@H](C1)n1cnc2c(NCc3cccc(Br)c3)ncnc12 |r,wU:12.15,10.10,(36.41,-23.55,;35.32,-24.63,;33.83,-24.23,;32.74,-25.33,;33.14,-26.81,;34.63,-27.21,;35.72,-26.12,;35.02,-28.69,;36.54,-29.01,;33.99,-29.84,;32.49,-29.52,;31.2,-30.36,;30.36,-29.07,;31.65,-28.23,;28.86,-28.74,;28.23,-27.34,;26.7,-27.5,;26.37,-29.01,;25.04,-29.78,;23.71,-29.01,;22.38,-29.78,;21.04,-29.01,;21.04,-27.47,;19.7,-26.7,;18.37,-27.47,;18.37,-29.01,;17.04,-29.78,;19.7,-29.78,;25.04,-31.32,;26.37,-32.09,;27.71,-31.32,;27.71,-29.78,)| Show InChI InChI=1S/C23H22BrN7O/c1-14-4-2-7-19(29-14)23(32)30-17-9-18(10-17)31-13-28-20-21(26-12-27-22(20)31)25-11-15-5-3-6-16(24)8-15/h2-8,12-13,17-18H,9-11H2,1H3,(H,30,32)(H,25,26,27)/t17-,18+ | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology
Curated by ChEMBL
| Assay Description
Inhibition of human CDK6/CyclinD3 |
Bioorg Med Chem Lett 27: 4399-4404 (2017)
Article DOI: 10.1016/j.bmcl.2017.08.018
BindingDB Entry DOI: 10.7270/Q2W66P60 |
More data for this
Ligand-Target Pair | |
Cyclin-dependent kinase 6/G1/S-specific cyclin-D3
(Homo sapiens (Human)) | BDBM50261164
(CHEMBL4103221)Show SMILES Cc1cccc(n1)C(=O)N[C@H]1C[C@H](C1)n1cnc2c(NCc3cccc(Cl)c3)ncnc12 |r,wU:12.15,10.10,(26.01,-22.02,;24.92,-23.11,;23.43,-22.71,;22.35,-23.8,;22.75,-25.29,;24.23,-25.68,;25.32,-24.6,;24.63,-27.17,;26.14,-27.49,;23.6,-28.32,;22.09,-28,;20.8,-28.83,;19.97,-27.54,;21.26,-26.71,;18.46,-27.22,;17.83,-25.81,;16.3,-25.98,;15.98,-27.48,;14.65,-28.26,;13.31,-27.48,;11.98,-28.26,;10.65,-27.48,;10.65,-25.94,;9.31,-25.18,;7.98,-25.94,;7.98,-27.48,;6.64,-28.26,;9.31,-28.26,;14.65,-29.8,;15.98,-30.56,;17.31,-29.8,;17.31,-28.26,)| Show InChI InChI=1S/C23H22ClN7O/c1-14-4-2-7-19(29-14)23(32)30-17-9-18(10-17)31-13-28-20-21(26-12-27-22(20)31)25-11-15-5-3-6-16(24)8-15/h2-8,12-13,17-18H,9-11H2,1H3,(H,30,32)(H,25,26,27)/t17-,18+ | PDB
UniProtKB/SwissProt
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Research Institute of Chemical Technology
Curated by ChEMBL
| Assay Description
Inhibition of human CDK6/CyclinD3 |
Bioorg Med Chem Lett 27: 4399-4404 (2017)
Article DOI: 10.1016/j.bmcl.2017.08.018
BindingDB Entry DOI: 10.7270/Q2W66P60 |
More data for this
Ligand-Target Pair | |
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