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USPatent US8846730

Compile data set for download or QSAR
Found 132 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM133313
PNG
(US8846730, 79)
Show SMILES CC(C)NOc1ccc(cc1C(=O)\N=c1/sc(cn1C[C@H]1CCCO1)C(C)(C)C)C(F)(F)F
Show InChI InChI=1S/C23H30F3N3O3S/c1-14(2)28-32-18-9-8-15(23(24,25)26)11-17(18)20(30)27-21-29(12-16-7-6-10-31-16)13-19(33-21)22(3,4)5/h8-9,11,13-14,16,28H,6-7,10,12H2,1-5H3/b27-21-/t16-/m1/s1
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US Patent
0.300 -55.3n/an/an/an/an/a7.430



AbbVie Inc.

US Patent


Assay Description
HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...


US Patent US8846730 (2014)


BindingDB Entry DOI: 10.7270/Q2028Q6Q
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Rattus norvegicus (Rat))
BDBM133307
PNG
(US8846730, 72)
Show SMILES CC(C)(C)C(=O)COc1ccc(cc1C(=O)\N=c1/sc(cn1C[C@H]1CCCO1)C(C)(C)C)C(F)(F)F
Show InChI InChI=1S/C26H33F3N2O4S/c1-24(2,3)20(32)15-35-19-10-9-16(26(27,28)29)12-18(19)22(33)30-23-31(13-17-8-7-11-34-17)14-21(36-23)25(4,5)6/h9-10,12,14,17H,7-8,11,13,15H2,1-6H3/b30-23-/t17-/m1/s1
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US Patent
0.300 -55.3n/an/an/an/an/a7.430



AbbVie Inc.

US Patent


Assay Description
HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...


US Patent US8846730 (2014)


BindingDB Entry DOI: 10.7270/Q2028Q6Q
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Rattus norvegicus (Rat))
BDBM133287
PNG
(US8846730, 40)
Show SMILES CC(C)(C)OC(=O)NNc1ccc(cc1C(=O)\N=c1\sc(cn1C[C@H]1CCCO1)C(C)(C)C)C(F)(F)F
Show InChI InChI=1S/C25H33F3N4O4S/c1-23(2,3)19-14-32(13-16-8-7-11-35-16)21(37-19)29-20(33)17-12-15(25(26,27)28)9-10-18(17)30-31-22(34)36-24(4,5)6/h9-10,12,14,16,30H,7-8,11,13H2,1-6H3,(H,31,34)/b29-21+/t16-/m1/s1
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US Patent
0.300 -55.3n/an/an/an/an/a7.430



AbbVie Inc.

US Patent


Assay Description
HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...


US Patent US8846730 (2014)


BindingDB Entry DOI: 10.7270/Q2028Q6Q
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Rattus norvegicus (Rat))
BDBM133276
PNG
(US8846730, 23)
Show SMILES CC(C)(C)c1cn(C[C@H]2CCCO2)\c(=N\C(=O)c2cc(ccc2OC[C@@H]2CCCO2)C(F)(F)F)s1
Show InChI InChI=1S/C25H31F3N2O4S/c1-24(2,3)21-14-30(13-17-6-4-10-32-17)23(35-21)29-22(31)19-12-16(25(26,27)28)8-9-20(19)34-15-18-7-5-11-33-18/h8-9,12,14,17-18H,4-7,10-11,13,15H2,1-3H3/b29-23-/t17-,18+/m1/s1
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US Patent
0.300 -55.3n/an/an/an/an/a7.430



AbbVie Inc.

US Patent


Assay Description
HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...


US Patent US8846730 (2014)


BindingDB Entry DOI: 10.7270/Q2028Q6Q
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM133287
PNG
(US8846730, 40)
Show SMILES CC(C)(C)OC(=O)NNc1ccc(cc1C(=O)\N=c1\sc(cn1C[C@H]1CCCO1)C(C)(C)C)C(F)(F)F
Show InChI InChI=1S/C25H33F3N4O4S/c1-23(2,3)19-14-32(13-16-8-7-11-35-16)21(37-19)29-20(33)17-12-15(25(26,27)28)9-10-18(17)30-31-22(34)36-24(4,5)6/h9-10,12,14,16,30H,7-8,11,13H2,1-6H3,(H,31,34)/b29-21+/t16-/m1/s1
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US Patent
0.400 -54.5n/an/an/an/an/a7.430



AbbVie Inc.

US Patent


Assay Description
HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...


US Patent US8846730 (2014)


BindingDB Entry DOI: 10.7270/Q2028Q6Q
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Rattus norvegicus (Rat))
BDBM133313
PNG
(US8846730, 79)
Show SMILES CC(C)NOc1ccc(cc1C(=O)\N=c1/sc(cn1C[C@H]1CCCO1)C(C)(C)C)C(F)(F)F
Show InChI InChI=1S/C23H30F3N3O3S/c1-14(2)28-32-18-9-8-15(23(24,25)26)11-17(18)20(30)27-21-29(12-16-7-6-10-31-16)13-19(33-21)22(3,4)5/h8-9,11,13-14,16,28H,6-7,10,12H2,1-5H3/b27-21-/t16-/m1/s1
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US Patent
0.5 -54.0n/an/an/an/an/a7.430



AbbVie Inc.

US Patent


Assay Description
HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...


US Patent US8846730 (2014)


BindingDB Entry DOI: 10.7270/Q2028Q6Q
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Rattus norvegicus (Rat))
BDBM133275
PNG
(US8846730, 22)
Show SMILES CC(C)(C)c1cn(C[C@H]2CCCO2)\c(=N\C(=O)c2cc(ccc2OC[C@H]2CCCO2)C(F)(F)F)s1
Show InChI InChI=1S/C25H31F3N2O4S/c1-24(2,3)21-14-30(13-17-6-4-10-32-17)23(35-21)29-22(31)19-12-16(25(26,27)28)8-9-20(19)34-15-18-7-5-11-33-18/h8-9,12,14,17-18H,4-7,10-11,13,15H2,1-3H3/b29-23-/t17-,18-/m1/s1
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US Patent
0.5 -54.0n/an/an/an/an/a7.430



AbbVie Inc.

US Patent


Assay Description
HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...


US Patent US8846730 (2014)


BindingDB Entry DOI: 10.7270/Q2028Q6Q
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM133276
PNG
(US8846730, 23)
Show SMILES CC(C)(C)c1cn(C[C@H]2CCCO2)\c(=N\C(=O)c2cc(ccc2OC[C@@H]2CCCO2)C(F)(F)F)s1
Show InChI InChI=1S/C25H31F3N2O4S/c1-24(2,3)21-14-30(13-17-6-4-10-32-17)23(35-21)29-22(31)19-12-16(25(26,27)28)8-9-20(19)34-15-18-7-5-11-33-18/h8-9,12,14,17-18H,4-7,10-11,13,15H2,1-3H3/b29-23-/t17-,18+/m1/s1
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US Patent
0.5 -54.0n/an/an/an/an/a7.430



AbbVie Inc.

US Patent


Assay Description
HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...


US Patent US8846730 (2014)


BindingDB Entry DOI: 10.7270/Q2028Q6Q
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Rattus norvegicus (Rat))
BDBM133315
PNG
(US8846730, 81)
Show SMILES C[C@@H](O)COc1ccc(cc1C(=O)\N=c1/sc(cn1C[C@H]1CCCO1)C(C)(C)C)C(F)(F)F
Show InChI InChI=1S/C23H29F3N2O4S/c1-14(29)13-32-18-8-7-15(23(24,25)26)10-17(18)20(30)27-21-28(11-16-6-5-9-31-16)12-19(33-21)22(2,3)4/h7-8,10,12,14,16,29H,5-6,9,11,13H2,1-4H3/b27-21-/t14-,16-/m1/s1
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US Patent
0.5 -54.0n/an/an/an/an/a7.430



AbbVie Inc.

US Patent


Assay Description
HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...


US Patent US8846730 (2014)


BindingDB Entry DOI: 10.7270/Q2028Q6Q
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Rattus norvegicus (Rat))
BDBM133308
PNG
(US8846730, 73)
Show SMILES CC(COc1ccc(cc1C(=O)\N=c1/sc(cn1C[C@H]1CCCO1)C(C)(C)C)C(F)(F)F)=NO |w:32.35|
Show InChI InChI=1S/C23H28F3N3O4S/c1-14(28-31)13-33-18-8-7-15(23(24,25)26)10-17(18)20(30)27-21-29(11-16-6-5-9-32-16)12-19(34-21)22(2,3)4/h7-8,10,12,16,31H,5-6,9,11,13H2,1-4H3/b27-21-,28-14+/t16-/m1/s1
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US Patent
0.5 -54.0n/an/an/an/an/a7.430



AbbVie Inc.

US Patent


Assay Description
HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...


US Patent US8846730 (2014)


BindingDB Entry DOI: 10.7270/Q2028Q6Q
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM133316
PNG
(US8846730, 83)
Show SMILES CC(C)(C)c1cn(CC2CCCO2)\c(=N\C(=O)c2cc(ccc2ON=C2CCCC2)C(F)(F)F)s1 |(-5.42,15.18,;-6.33,13.94,;-5.08,13.03,;-7.57,14.84,;-7.23,12.69,;-8.77,12.69,;-9.25,11.23,;-10.71,10.75,;-11.86,11.78,;-13.36,11.46,;-14.13,12.79,;-13.1,13.94,;-11.7,13.31,;-8,10.32,;-8,8.78,;-6.67,8.01,;-5.33,8.78,;-6.67,6.47,;-8,5.7,;-8,4.16,;-6.67,3.39,;-5.33,4.16,;-5.33,5.7,;-4,6.47,;-2.67,5.7,;-2.67,4.16,;-1.42,3.25,;-1.9,1.79,;-3.44,1.79,;-3.91,3.25,;-9.34,3.39,;-10.67,2.62,;-10.11,4.72,;-8.57,2.06,;-6.76,11.23,)|
Show InChI InChI=1S/C25H30F3N3O3S/c1-24(2,3)21-15-31(14-18-9-6-12-33-18)23(35-21)29-22(32)19-13-16(25(26,27)28)10-11-20(19)34-30-17-7-4-5-8-17/h10-11,13,15,18H,4-9,12,14H2,1-3H3/b29-23-
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US Patent
0.5 -54.0n/an/an/an/an/a7.430



AbbVie Inc.

US Patent


Assay Description
HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...


US Patent US8846730 (2014)


BindingDB Entry DOI: 10.7270/Q2028Q6Q
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Rattus norvegicus (Rat))
BDBM9807
PNG
(US8846730, 50)
Show SMILES CC(C)(O)CCOc1ccc(cc1C(=O)\N=c1/sc(cn1C[C@H]1CCCO1)C(C)(C)C)C(F)(F)F
Show InChI InChI=1S/C25H33F3N2O4S/c1-23(2,3)20-15-30(14-17-7-6-11-33-17)22(35-20)29-21(31)18-13-16(25(26,27)28)8-9-19(18)34-12-10-24(4,5)32/h8-9,13,15,17,32H,6-7,10-12,14H2,1-5H3/b29-22-/t17-/m1/s1
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US Patent
0.5 -54.0n/an/an/an/an/a7.430



AbbVie Inc.

US Patent


Assay Description
HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...


US Patent US8846730 (2014)


BindingDB Entry DOI: 10.7270/Q2028Q6Q
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Rattus norvegicus (Rat))
BDBM9651
PNG
(US8846730, 4)
Show SMILES CC(C)(C)c1cn(C[C@H]2CCCO2)\c(=N\C(=O)c2cc(ccc2OC[C@@H]2CCCCN2)C(F)(F)F)s1
Show InChI InChI=1S/C26H34F3N3O3S/c1-25(2,3)22-15-32(14-19-8-6-12-34-19)24(36-22)31-23(33)20-13-17(26(27,28)29)9-10-21(20)35-16-18-7-4-5-11-30-18/h9-10,13,15,18-19,30H,4-8,11-12,14,16H2,1-3H3/b31-24-/t18-,19+/m0/s1
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US Patent
0.600 -53.5n/an/an/an/an/a7.430



AbbVie Inc.

US Patent


Assay Description
HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...


US Patent US8846730 (2014)


BindingDB Entry DOI: 10.7270/Q2028Q6Q
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM9652
PNG
(US8846730, 5)
Show SMILES CN1CCCC[C@H]1COc1ccc(cc1C(=O)\N=c1/sc(cn1C[C@H]1CCCO1)C(C)(C)C)C(F)(F)F
Show InChI InChI=1S/C27H36F3N3O3S/c1-26(2,3)23-16-33(15-20-9-7-13-35-20)25(37-23)31-24(34)21-14-18(27(28,29)30)10-11-22(21)36-17-19-8-5-6-12-32(19)4/h10-11,14,16,19-20H,5-9,12-13,15,17H2,1-4H3/b31-25-/t19-,20+/m0/s1
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US Patent
0.700 -53.1n/an/an/an/an/a7.430



AbbVie Inc.

US Patent


Assay Description
HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...


US Patent US8846730 (2014)


BindingDB Entry DOI: 10.7270/Q2028Q6Q
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM9651
PNG
(US8846730, 4)
Show SMILES CC(C)(C)c1cn(C[C@H]2CCCO2)\c(=N\C(=O)c2cc(ccc2OC[C@@H]2CCCCN2)C(F)(F)F)s1
Show InChI InChI=1S/C26H34F3N3O3S/c1-25(2,3)22-15-32(14-19-8-6-12-34-19)24(36-22)31-23(33)20-13-17(26(27,28)29)9-10-21(20)35-16-18-7-4-5-11-30-18/h9-10,13,15,18-19,30H,4-8,11-12,14,16H2,1-3H3/b31-24-/t18-,19+/m0/s1
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US Patent
0.700 -53.1n/an/an/an/an/a7.430



AbbVie Inc.

US Patent


Assay Description
HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...


US Patent US8846730 (2014)


BindingDB Entry DOI: 10.7270/Q2028Q6Q
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Rattus norvegicus (Rat))
BDBM9842
PNG
(US8846730, 65 | US8846730, 76)
Show SMILES CC(C)(C)NOc1ccc(cc1C(=O)\N=c1/sc(cn1C[C@H]1CCCO1)C(C)(C)C)C(F)(F)F
Show InChI InChI=1S/C24H32F3N3O3S/c1-22(2,3)19-14-30(13-16-8-7-11-32-16)21(34-19)28-20(31)17-12-15(24(25,26)27)9-10-18(17)33-29-23(4,5)6/h9-10,12,14,16,29H,7-8,11,13H2,1-6H3/b28-21-/t16-/m1/s1
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US Patent
0.800 -52.8n/an/an/an/an/a7.430



AbbVie Inc.

US Patent


Assay Description
HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...


US Patent US8846730 (2014)


BindingDB Entry DOI: 10.7270/Q2028Q6Q
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM133307
PNG
(US8846730, 72)
Show SMILES CC(C)(C)C(=O)COc1ccc(cc1C(=O)\N=c1/sc(cn1C[C@H]1CCCO1)C(C)(C)C)C(F)(F)F
Show InChI InChI=1S/C26H33F3N2O4S/c1-24(2,3)20(32)15-35-19-10-9-16(26(27,28)29)12-18(19)22(33)30-23-31(13-17-8-7-11-34-17)14-21(36-23)25(4,5)6/h9-10,12,14,17H,7-8,11,13,15H2,1-6H3/b30-23-/t17-/m1/s1
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US Patent
0.900 -52.5n/an/an/an/an/a7.430



AbbVie Inc.

US Patent


Assay Description
HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...


US Patent US8846730 (2014)


BindingDB Entry DOI: 10.7270/Q2028Q6Q
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Rattus norvegicus (Rat))
BDBM9812
PNG
(US8846730, 69)
Show SMILES Clc1ccc(OCCCC(=O)NN\C=C2/C=CC=CC2=O)c(Cl)c1 |c:15,17|
Show InChI InChI=1S/C17H16Cl2N2O3/c18-13-7-8-16(14(19)10-13)24-9-3-6-17(23)21-20-11-12-4-1-2-5-15(12)22/h1-2,4-5,7-8,10-11,20H,3,6,9H2,(H,21,23)/b12-11+
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US Patent
0.900 -52.5n/an/an/an/an/a7.430



AbbVie Inc.

US Patent


Assay Description
HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...


US Patent US8846730 (2014)


BindingDB Entry DOI: 10.7270/Q2028Q6Q
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Rattus norvegicus (Rat))
BDBM133294
PNG
(US8846730, 51)
Show SMILES CN1CCC[C@H]1COc1ccc(cc1C(=S)\N=c1/sc(cn1C[C@H]1CCCO1)C(C)(C)C)C(F)(F)F
Show InChI InChI=1S/C26H34F3N3O2S2/c1-25(2,3)22-15-32(14-19-8-6-12-33-19)24(36-22)30-23(35)20-13-17(26(27,28)29)9-10-21(20)34-16-18-7-5-11-31(18)4/h9-10,13,15,18-19H,5-8,11-12,14,16H2,1-4H3/b30-24-/t18-,19+/m0/s1
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0.900 -52.5n/an/an/an/an/a7.430



AbbVie Inc.

US Patent


Assay Description
HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...


US Patent US8846730 (2014)


BindingDB Entry DOI: 10.7270/Q2028Q6Q
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM133315
PNG
(US8846730, 81)
Show SMILES C[C@@H](O)COc1ccc(cc1C(=O)\N=c1/sc(cn1C[C@H]1CCCO1)C(C)(C)C)C(F)(F)F
Show InChI InChI=1S/C23H29F3N2O4S/c1-14(29)13-32-18-8-7-15(23(24,25)26)10-17(18)20(30)27-21-28(11-16-6-5-9-31-16)12-19(33-21)22(2,3)4/h7-8,10,12,14,16,29H,5-6,9,11,13H2,1-4H3/b27-21-/t14-,16-/m1/s1
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1.10 -52.0n/an/an/an/an/a7.430



AbbVie Inc.

US Patent


Assay Description
HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...


US Patent US8846730 (2014)


BindingDB Entry DOI: 10.7270/Q2028Q6Q
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Rattus norvegicus (Rat))
BDBM133316
PNG
(US8846730, 83)
Show SMILES CC(C)(C)c1cn(CC2CCCO2)\c(=N\C(=O)c2cc(ccc2ON=C2CCCC2)C(F)(F)F)s1 |(-5.42,15.18,;-6.33,13.94,;-5.08,13.03,;-7.57,14.84,;-7.23,12.69,;-8.77,12.69,;-9.25,11.23,;-10.71,10.75,;-11.86,11.78,;-13.36,11.46,;-14.13,12.79,;-13.1,13.94,;-11.7,13.31,;-8,10.32,;-8,8.78,;-6.67,8.01,;-5.33,8.78,;-6.67,6.47,;-8,5.7,;-8,4.16,;-6.67,3.39,;-5.33,4.16,;-5.33,5.7,;-4,6.47,;-2.67,5.7,;-2.67,4.16,;-1.42,3.25,;-1.9,1.79,;-3.44,1.79,;-3.91,3.25,;-9.34,3.39,;-10.67,2.62,;-10.11,4.72,;-8.57,2.06,;-6.76,11.23,)|
Show InChI InChI=1S/C25H30F3N3O3S/c1-24(2,3)21-15-31(14-18-9-6-12-33-18)23(35-21)29-22(32)19-13-16(25(26,27)28)10-11-20(19)34-30-17-7-4-5-8-17/h10-11,13,15,18H,4-9,12,14H2,1-3H3/b29-23-
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1.20 -51.8n/an/an/an/an/a7.430



AbbVie Inc.

US Patent


Assay Description
HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...


US Patent US8846730 (2014)


BindingDB Entry DOI: 10.7270/Q2028Q6Q
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM133310
PNG
(US8846730, 75)
Show SMILES CC(=O)NOc1ccc(cc1C(=O)\N=c1/sc(cn1C[C@H]1CCCO1)C(C)(C)C)C(F)(F)F
Show InChI InChI=1S/C22H26F3N3O4S/c1-13(29)27-32-17-8-7-14(22(23,24)25)10-16(17)19(30)26-20-28(11-15-6-5-9-31-15)12-18(33-20)21(2,3)4/h7-8,10,12,15H,5-6,9,11H2,1-4H3,(H,27,29)/b26-20-/t15-/m1/s1
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1.20 -51.8n/an/an/an/an/a7.430



AbbVie Inc.

US Patent


Assay Description
HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...


US Patent US8846730 (2014)


BindingDB Entry DOI: 10.7270/Q2028Q6Q
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM133294
PNG
(US8846730, 51)
Show SMILES CN1CCC[C@H]1COc1ccc(cc1C(=S)\N=c1/sc(cn1C[C@H]1CCCO1)C(C)(C)C)C(F)(F)F
Show InChI InChI=1S/C26H34F3N3O2S2/c1-25(2,3)22-15-32(14-19-8-6-12-33-19)24(36-22)30-23(35)20-13-17(26(27,28)29)9-10-21(20)34-16-18-7-5-11-31(18)4/h9-10,13,15,18-19H,5-8,11-12,14,16H2,1-4H3/b30-24-/t18-,19+/m0/s1
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US Patent
1.30 -51.6n/an/an/an/an/a7.430



AbbVie Inc.

US Patent


Assay Description
HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...


US Patent US8846730 (2014)


BindingDB Entry DOI: 10.7270/Q2028Q6Q
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM9807
PNG
(US8846730, 50)
Show SMILES CC(C)(O)CCOc1ccc(cc1C(=O)\N=c1/sc(cn1C[C@H]1CCCO1)C(C)(C)C)C(F)(F)F
Show InChI InChI=1S/C25H33F3N2O4S/c1-23(2,3)20-15-30(14-17-7-6-11-33-17)22(35-20)29-21(31)18-13-16(25(26,27)28)8-9-19(18)34-12-10-24(4,5)32/h8-9,13,15,17,32H,6-7,10-12,14H2,1-5H3/b29-22-/t17-/m1/s1
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1.30 -51.6n/an/an/an/an/a7.430



AbbVie Inc.

US Patent


Assay Description
HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...


US Patent US8846730 (2014)


BindingDB Entry DOI: 10.7270/Q2028Q6Q
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Rattus norvegicus (Rat))
BDBM9652
PNG
(US8846730, 5)
Show SMILES CN1CCCC[C@H]1COc1ccc(cc1C(=O)\N=c1/sc(cn1C[C@H]1CCCO1)C(C)(C)C)C(F)(F)F
Show InChI InChI=1S/C27H36F3N3O3S/c1-26(2,3)23-16-33(15-20-9-7-13-35-20)25(37-23)31-24(34)21-14-18(27(28,29)30)10-11-22(21)36-17-19-8-5-6-12-32(19)4/h10-11,14,16,19-20H,5-9,12-13,15,17H2,1-4H3/b31-25-/t19-,20+/m0/s1
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1.40 -51.4n/an/an/an/an/a7.430



AbbVie Inc.

US Patent


Assay Description
HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...


US Patent US8846730 (2014)


BindingDB Entry DOI: 10.7270/Q2028Q6Q
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Rattus norvegicus (Rat))
BDBM133297
PNG
(US8846730, 54)
Show SMILES CN1C[C@H](F)C[C@H]1COc1ccc(cc1C(=O)\N=c1/sc(cn1C[C@H]1CCCO1)C(C)(C)C)C(F)(F)F
Show InChI InChI=1S/C26H33F4N3O3S/c1-25(2,3)22-14-33(13-19-6-5-9-35-19)24(37-22)31-23(34)20-10-16(26(28,29)30)7-8-21(20)36-15-18-11-17(27)12-32(18)4/h7-8,10,14,17-19H,5-6,9,11-13,15H2,1-4H3/b31-24-/t17-,18+,19-/m1/s1
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1.5 -51.2n/an/an/an/an/a7.430



AbbVie Inc.

US Patent


Assay Description
HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...


US Patent US8846730 (2014)


BindingDB Entry DOI: 10.7270/Q2028Q6Q
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Rattus norvegicus (Rat))
BDBM9880
PNG
(US8846730, 82)
Show SMILES CC(C)(C)CO\C=N\CCCOc1ccc(cc1C(=O)\N=c1/sc(cn1C[C@H]1CCCO1)C(C)(C)C)C(F)(F)F
Show InChI InChI=1S/C29H40F3N3O4S/c1-27(2,3)18-37-19-33-12-8-14-39-23-11-10-20(29(30,31)32)15-22(23)25(36)34-26-35(16-21-9-7-13-38-21)17-24(40-26)28(4,5)6/h10-11,15,17,19,21H,7-9,12-14,16,18H2,1-6H3/b33-19+,34-26-/t21-/m1/s1
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1.70 -50.9n/an/an/an/an/a7.430



AbbVie Inc.

US Patent


Assay Description
HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...


US Patent US8846730 (2014)


BindingDB Entry DOI: 10.7270/Q2028Q6Q
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Rattus norvegicus (Rat))
BDBM133286
PNG
(US8846730, 39)
Show SMILES CC(C)(C)NNc1ccc(cc1C(=O)\N=c1/sc(cn1C[C@H]1CCCO1)C(C)(C)C)C(F)(F)F
Show InChI InChI=1S/C24H33F3N4O2S/c1-22(2,3)19-14-31(13-16-8-7-11-33-16)21(34-19)28-20(32)17-12-15(24(25,26)27)9-10-18(17)29-30-23(4,5)6/h9-10,12,14,16,29-30H,7-8,11,13H2,1-6H3/b28-21-/t16-/m1/s1
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1.70 -50.9n/an/an/an/an/a7.430



AbbVie Inc.

US Patent


Assay Description
HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...


US Patent US8846730 (2014)


BindingDB Entry DOI: 10.7270/Q2028Q6Q
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM133308
PNG
(US8846730, 73)
Show SMILES CC(COc1ccc(cc1C(=O)\N=c1/sc(cn1C[C@H]1CCCO1)C(C)(C)C)C(F)(F)F)=NO |w:32.35|
Show InChI InChI=1S/C23H28F3N3O4S/c1-14(28-31)13-33-18-8-7-15(23(24,25)26)10-17(18)20(30)27-21-29(11-16-6-5-9-32-16)12-19(34-21)22(2,3)4/h7-8,10,12,16,31H,5-6,9,11,13H2,1-4H3/b27-21-,28-14+/t16-/m1/s1
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1.80 -50.7n/an/an/an/an/a7.430



AbbVie Inc.

US Patent


Assay Description
HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...


US Patent US8846730 (2014)


BindingDB Entry DOI: 10.7270/Q2028Q6Q
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM9842
PNG
(US8846730, 65 | US8846730, 76)
Show SMILES CC(C)(C)NOc1ccc(cc1C(=O)\N=c1/sc(cn1C[C@H]1CCCO1)C(C)(C)C)C(F)(F)F
Show InChI InChI=1S/C24H32F3N3O3S/c1-22(2,3)19-14-30(13-16-8-7-11-32-16)21(34-19)28-20(31)17-12-15(24(25,26)27)9-10-18(17)33-29-23(4,5)6/h9-10,12,14,16,29H,7-8,11,13H2,1-6H3/b28-21-/t16-/m1/s1
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1.80 -50.7n/an/an/an/an/a7.430



AbbVie Inc.

US Patent


Assay Description
HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...


US Patent US8846730 (2014)


BindingDB Entry DOI: 10.7270/Q2028Q6Q
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Rattus norvegicus (Rat))
BDBM133290
PNG
(US8846730, 44)
Show SMILES CC(C)(C)c1cn(C[C@H]2CCCO2)\c(=N\C(=O)c2cc(ccc2OC[C@@H]2CCCN2)C(F)(F)F)s1
Show InChI InChI=1S/C25H32F3N3O3S/c1-24(2,3)21-14-31(13-18-7-5-11-33-18)23(35-21)30-22(32)19-12-16(25(26,27)28)8-9-20(19)34-15-17-6-4-10-29-17/h8-9,12,14,17-18,29H,4-7,10-11,13,15H2,1-3H3/b30-23-/t17-,18+/m0/s1
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2 -50.5n/an/an/an/an/a7.430



AbbVie Inc.

US Patent


Assay Description
HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...


US Patent US8846730 (2014)


BindingDB Entry DOI: 10.7270/Q2028Q6Q
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM133297
PNG
(US8846730, 54)
Show SMILES CN1C[C@H](F)C[C@H]1COc1ccc(cc1C(=O)\N=c1/sc(cn1C[C@H]1CCCO1)C(C)(C)C)C(F)(F)F
Show InChI InChI=1S/C26H33F4N3O3S/c1-25(2,3)22-14-33(13-19-6-5-9-35-19)24(37-22)31-23(34)20-10-16(26(28,29)30)7-8-21(20)36-15-18-11-17(27)12-32(18)4/h7-8,10,14,17-19H,5-6,9,11-13,15H2,1-4H3/b31-24-/t17-,18+,19-/m1/s1
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2 -50.5n/an/an/an/an/a7.430



AbbVie Inc.

US Patent


Assay Description
HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...


US Patent US8846730 (2014)


BindingDB Entry DOI: 10.7270/Q2028Q6Q
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Rattus norvegicus (Rat))
BDBM133317
PNG
(US8846730, 84)
Show SMILES CC(=O)C(C)=NOc1ccc(cc1C(=O)\N=c1/sc(cn1C[C@H]1CCCO1)C(C)(C)C)C(F)(F)F |w:5.5|
Show InChI InChI=1S/C24H28F3N3O4S/c1-14(15(2)31)29-34-19-9-8-16(24(25,26)27)11-18(19)21(32)28-22-30(12-17-7-6-10-33-17)13-20(35-22)23(3,4)5/h8-9,11,13,17H,6-7,10,12H2,1-5H3/b28-22-,29-14+/t17-/m1/s1
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2.40 -50.0n/an/an/an/an/a7.430



AbbVie Inc.

US Patent


Assay Description
HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...


US Patent US8846730 (2014)


BindingDB Entry DOI: 10.7270/Q2028Q6Q
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Rattus norvegicus (Rat))
BDBM133285
PNG
(US8846730, 38)
Show SMILES CC(C)(C)c1cn(C[C@H]2CCCO2)\c(=N\C(=O)c2cc(ccc2OCc2nccs2)C(F)(F)F)s1
Show InChI InChI=1S/C24H26F3N3O3S2/c1-23(2,3)19-13-30(12-16-5-4-9-32-16)22(35-19)29-21(31)17-11-15(24(25,26)27)6-7-18(17)33-14-20-28-8-10-34-20/h6-8,10-11,13,16H,4-5,9,12,14H2,1-3H3/b29-22-/t16-/m1/s1
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2.5 -49.9n/an/an/an/an/a7.430



AbbVie Inc.

US Patent


Assay Description
HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...


US Patent US8846730 (2014)


BindingDB Entry DOI: 10.7270/Q2028Q6Q
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Rattus norvegicus (Rat))
BDBM133310
PNG
(US8846730, 75)
Show SMILES CC(=O)NOc1ccc(cc1C(=O)\N=c1/sc(cn1C[C@H]1CCCO1)C(C)(C)C)C(F)(F)F
Show InChI InChI=1S/C22H26F3N3O4S/c1-13(29)27-32-17-8-7-14(22(23,24)25)10-16(17)19(30)26-20-28(11-15-6-5-9-31-15)12-18(33-20)21(2,3)4/h7-8,10,12,15H,5-6,9,11H2,1-4H3,(H,27,29)/b26-20-/t15-/m1/s1
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2.5 -49.9n/an/an/an/an/a7.430



AbbVie Inc.

US Patent


Assay Description
HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...


US Patent US8846730 (2014)


BindingDB Entry DOI: 10.7270/Q2028Q6Q
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Rattus norvegicus (Rat))
BDBM133281
PNG
(US8846730, 33)
Show SMILES CC(C)(C)c1cn(C[C@@H]2CCCO2)\c(=N\C(=O)c2cc(ccc2OC[C@H](N)CO)C(F)(F)F)s1
Show InChI InChI=1S/C23H30F3N3O4S/c1-22(2,3)19-11-29(10-16-5-4-8-32-16)21(34-19)28-20(31)17-9-14(23(24,25)26)6-7-18(17)33-13-15(27)12-30/h6-7,9,11,15-16,30H,4-5,8,10,12-13,27H2,1-3H3/b28-21-/t15-,16+/m1/s1
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2.80 -49.6n/an/an/an/an/a7.430



AbbVie Inc.

US Patent


Assay Description
HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...


US Patent US8846730 (2014)


BindingDB Entry DOI: 10.7270/Q2028Q6Q
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Rattus norvegicus (Rat))
BDBM133283
PNG
(US8846730, 36)
Show SMILES CC(C)(C)c1cn(C[C@H]2CCCO2)\c(=N\C(=O)c2cc(ccc2OCc2ccccc2)C(F)(F)F)s1
Show InChI InChI=1S/C27H29F3N2O3S/c1-26(2,3)23-16-32(15-20-10-7-13-34-20)25(36-23)31-24(33)21-14-19(27(28,29)30)11-12-22(21)35-17-18-8-5-4-6-9-18/h4-6,8-9,11-12,14,16,20H,7,10,13,15,17H2,1-3H3/b31-25-/t20-/m1/s1
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2.90 -49.5n/an/an/an/an/a7.430



AbbVie Inc.

US Patent


Assay Description
HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...


US Patent US8846730 (2014)


BindingDB Entry DOI: 10.7270/Q2028Q6Q
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Rattus norvegicus (Rat))
BDBM133293
PNG
(US8846730, 48)
Show SMILES CC(C)(C)c1cn(C[C@H]2CCCO2)\c(=N\C(=O)c2cc(ccc2OC[C@@H]2CCCN2S(C)(=O)=O)C(F)(F)F)s1
Show InChI InChI=1S/C26H34F3N3O5S2/c1-25(2,3)22-15-31(14-19-8-6-12-36-19)24(38-22)30-23(33)20-13-17(26(27,28)29)9-10-21(20)37-16-18-7-5-11-32(18)39(4,34)35/h9-10,13,15,18-19H,5-8,11-12,14,16H2,1-4H3/b30-24-/t18-,19+/m0/s1
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3 -49.5n/an/an/an/an/a7.430



AbbVie Inc.

US Patent


Assay Description
HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...


US Patent US8846730 (2014)


BindingDB Entry DOI: 10.7270/Q2028Q6Q
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM133275
PNG
(US8846730, 22)
Show SMILES CC(C)(C)c1cn(C[C@H]2CCCO2)\c(=N\C(=O)c2cc(ccc2OC[C@H]2CCCO2)C(F)(F)F)s1
Show InChI InChI=1S/C25H31F3N2O4S/c1-24(2,3)21-14-30(13-17-6-4-10-32-17)23(35-21)29-22(31)19-12-16(25(26,27)28)8-9-20(19)34-15-18-7-5-11-33-18/h8-9,12,14,17-18H,4-7,10-11,13,15H2,1-3H3/b29-23-/t17-,18-/m1/s1
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3 -49.5n/an/an/an/an/a7.430



AbbVie Inc.

US Patent


Assay Description
HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...


US Patent US8846730 (2014)


BindingDB Entry DOI: 10.7270/Q2028Q6Q
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Rattus norvegicus (Rat))
BDBM133265
PNG
(US8846730, 2)
Show SMILES CC(C)(C)c1cn(C[C@H]2CCCO2)\c(=N\C(=O)c2cc(ccc2OC[C@@H]2CCN2)C(F)(F)F)s1
Show InChI InChI=1S/C24H30F3N3O3S/c1-23(2,3)20-13-30(12-17-5-4-10-32-17)22(34-20)29-21(31)18-11-15(24(25,26)27)6-7-19(18)33-14-16-8-9-28-16/h6-7,11,13,16-17,28H,4-5,8-10,12,14H2,1-3H3/b29-22-/t16-,17+/m0/s1
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3 -49.5n/an/an/an/an/a7.430



AbbVie Inc.

US Patent


Assay Description
HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...


US Patent US8846730 (2014)


BindingDB Entry DOI: 10.7270/Q2028Q6Q
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM133295
PNG
(US8846730, 53)
Show SMILES CN1C[C@@H](F)C[C@H]1COc1ccc(cc1C(=O)\N=c1/sc(cn1C[C@H]1CCCO1)C(C)(C)C)C(F)(F)F
Show InChI InChI=1S/C26H33F4N3O3S/c1-25(2,3)22-14-33(13-19-6-5-9-35-19)24(37-22)31-23(34)20-10-16(26(28,29)30)7-8-21(20)36-15-18-11-17(27)12-32(18)4/h7-8,10,14,17-19H,5-6,9,11-13,15H2,1-4H3/b31-24-/t17-,18-,19+/m0/s1
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3 -49.5n/an/an/an/an/a7.430



AbbVie Inc.

US Patent


Assay Description
HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...


US Patent US8846730 (2014)


BindingDB Entry DOI: 10.7270/Q2028Q6Q
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM133317
PNG
(US8846730, 84)
Show SMILES CC(=O)C(C)=NOc1ccc(cc1C(=O)\N=c1/sc(cn1C[C@H]1CCCO1)C(C)(C)C)C(F)(F)F |w:5.5|
Show InChI InChI=1S/C24H28F3N3O4S/c1-14(15(2)31)29-34-19-9-8-16(24(25,26)27)11-18(19)21(32)28-22-30(12-17-7-6-10-33-17)13-20(35-22)23(3,4)5/h8-9,11,13,17H,6-7,10,12H2,1-5H3/b28-22-,29-14+/t17-/m1/s1
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3.30 -49.2n/an/an/an/an/a7.430



AbbVie Inc.

US Patent


Assay Description
HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...


US Patent US8846730 (2014)


BindingDB Entry DOI: 10.7270/Q2028Q6Q
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Rattus norvegicus (Rat))
BDBM133289
PNG
(US8846730, 43)
Show SMILES CN1[C@H](COc2ccc(cc2C(=O)\N=c2/sc(cn2C[C@H]2CCCO2)C(C)(C)C)C(F)(F)F)CCC1=O
Show InChI InChI=1S/C26H32F3N3O4S/c1-25(2,3)21-14-32(13-18-6-5-11-35-18)24(37-21)30-23(34)19-12-16(26(27,28)29)7-9-20(19)36-15-17-8-10-22(33)31(17)4/h7,9,12,14,17-18H,5-6,8,10-11,13,15H2,1-4H3/b30-24-/t17-,18+/m0/s1
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3.30 -49.2n/an/an/an/an/a7.430



AbbVie Inc.

US Patent


Assay Description
HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...


US Patent US8846730 (2014)


BindingDB Entry DOI: 10.7270/Q2028Q6Q
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Rattus norvegicus (Rat))
BDBM133277
PNG
(US8846730, 24)
Show SMILES CN1CCC[C@H]1COc1ccc(cc1C(=O)\N=c1/sc(cn1C[C@H]1CCCO1)C(C)(C)C)C(F)(F)F
Show InChI InChI=1S/C26H34F3N3O3S/c1-25(2,3)22-15-32(14-19-8-6-12-34-19)24(36-22)30-23(33)20-13-17(26(27,28)29)9-10-21(20)35-16-18-7-5-11-31(18)4/h9-10,13,15,18-19H,5-8,11-12,14,16H2,1-4H3/b30-24-/t18-,19+/m0/s1
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3.40 -49.1n/an/an/an/an/a7.430



AbbVie Inc.

US Patent


Assay Description
HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...


US Patent US8846730 (2014)


BindingDB Entry DOI: 10.7270/Q2028Q6Q
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM9812
PNG
(US8846730, 69)
Show SMILES Clc1ccc(OCCCC(=O)NN\C=C2/C=CC=CC2=O)c(Cl)c1 |c:15,17|
Show InChI InChI=1S/C17H16Cl2N2O3/c18-13-7-8-16(14(19)10-13)24-9-3-6-17(23)21-20-11-12-4-1-2-5-15(12)22/h1-2,4-5,7-8,10-11,20H,3,6,9H2,(H,21,23)/b12-11+
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3.60 -49.0n/an/an/an/an/a7.430



AbbVie Inc.

US Patent


Assay Description
HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...


US Patent US8846730 (2014)


BindingDB Entry DOI: 10.7270/Q2028Q6Q
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Rattus norvegicus (Rat))
BDBM133295
PNG
(US8846730, 53)
Show SMILES CN1C[C@@H](F)C[C@H]1COc1ccc(cc1C(=O)\N=c1/sc(cn1C[C@H]1CCCO1)C(C)(C)C)C(F)(F)F
Show InChI InChI=1S/C26H33F4N3O3S/c1-25(2,3)22-14-33(13-19-6-5-9-35-19)24(37-22)31-23(34)20-10-16(26(28,29)30)7-8-21(20)36-15-18-11-17(27)12-32(18)4/h7-8,10,14,17-19H,5-6,9,11-13,15H2,1-4H3/b31-24-/t17-,18-,19+/m0/s1
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3.60 -49.0n/an/an/an/an/a7.430



AbbVie Inc.

US Patent


Assay Description
HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...


US Patent US8846730 (2014)


BindingDB Entry DOI: 10.7270/Q2028Q6Q
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM133286
PNG
(US8846730, 39)
Show SMILES CC(C)(C)NNc1ccc(cc1C(=O)\N=c1/sc(cn1C[C@H]1CCCO1)C(C)(C)C)C(F)(F)F
Show InChI InChI=1S/C24H33F3N4O2S/c1-22(2,3)19-14-31(13-16-8-7-11-33-16)21(34-19)28-20(32)17-12-15(24(25,26)27)9-10-18(17)29-30-23(4,5)6/h9-10,12,14,16,29-30H,7-8,11,13H2,1-6H3/b28-21-/t16-/m1/s1
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3.70 -48.9n/an/an/an/an/a7.430



AbbVie Inc.

US Patent


Assay Description
HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...


US Patent US8846730 (2014)


BindingDB Entry DOI: 10.7270/Q2028Q6Q
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Rattus norvegicus (Rat))
BDBM133306
PNG
(US8846730, 71)
Show SMILES CC(C)(C)C(\COc1ccc(cc1C(=O)\N=c1/sc(cn1C[C@H]1CCCO1)C(C)(C)C)C(F)(F)F)=N/O
Show InChI InChI=1S/C26H34F3N3O4S/c1-24(2,3)20(31-34)15-36-19-10-9-16(26(27,28)29)12-18(19)22(33)30-23-32(13-17-8-7-11-35-17)14-21(37-23)25(4,5)6/h9-10,12,14,17,34H,7-8,11,13,15H2,1-6H3/b30-23-,31-20-/t17-/m1/s1
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4.10 -48.7n/an/an/an/an/a7.430



AbbVie Inc.

US Patent


Assay Description
HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...


US Patent US8846730 (2014)


BindingDB Entry DOI: 10.7270/Q2028Q6Q
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM133314
PNG
(US8846730, 80)
Show SMILES CC(=NOc1ccc(cc1C(=O)\N=c1/sc(cn1C[C@H]1CCCO1)C(C)(C)C)C(F)(F)F)C(F)(F)F |w:2.2|
Show InChI InChI=1S/C23H25F6N3O3S/c1-13(22(24,25)26)31-35-17-8-7-14(23(27,28)29)10-16(17)19(33)30-20-32(11-15-6-5-9-34-15)12-18(36-20)21(2,3)4/h7-8,10,12,15H,5-6,9,11H2,1-4H3/b30-20-,31-13+/t15-/m1/s1
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4.40 -48.5n/an/an/an/an/a7.430



AbbVie Inc.

US Patent


Assay Description
HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...


US Patent US8846730 (2014)


BindingDB Entry DOI: 10.7270/Q2028Q6Q
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Rattus norvegicus (Rat))
BDBM133266
PNG
(US8846730, 3)
Show SMILES CN1CC[C@H]1COc1ccc(cc1C(=O)\N=c1/sc(cn1C[C@H]1CCCO1)C(C)(C)C)C(F)(F)F
Show InChI InChI=1S/C25H32F3N3O3S/c1-24(2,3)21-14-31(13-18-6-5-11-33-18)23(35-21)29-22(32)19-12-16(25(26,27)28)7-8-20(19)34-15-17-9-10-30(17)4/h7-8,12,14,17-18H,5-6,9-11,13,15H2,1-4H3/b29-23-/t17-,18+/m0/s1
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4.5 -48.4n/an/an/an/an/a7.430



AbbVie Inc.

US Patent


Assay Description
HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...


US Patent US8846730 (2014)


BindingDB Entry DOI: 10.7270/Q2028Q6Q
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Rattus norvegicus (Rat))
BDBM133312
PNG
(US8846730, 78)
Show SMILES CCN(CC)Oc1ccc(cc1C(=O)\N=c1/sc(cn1C[C@H]1CCCO1)C(C)(C)C)C(F)(F)F
Show InChI InChI=1S/C24H32F3N3O3S/c1-6-30(7-2)33-19-11-10-16(24(25,26)27)13-18(19)21(31)28-22-29(14-17-9-8-12-32-17)15-20(34-22)23(3,4)5/h10-11,13,15,17H,6-9,12,14H2,1-5H3/b28-22-/t17-/m1/s1
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4.60 -48.4n/an/an/an/an/a7.430



AbbVie Inc.

US Patent


Assay Description
HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...


US Patent US8846730 (2014)


BindingDB Entry DOI: 10.7270/Q2028Q6Q
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM133290
PNG
(US8846730, 44)
Show SMILES CC(C)(C)c1cn(C[C@H]2CCCO2)\c(=N\C(=O)c2cc(ccc2OC[C@@H]2CCCN2)C(F)(F)F)s1
Show InChI InChI=1S/C25H32F3N3O3S/c1-24(2,3)21-14-31(13-18-7-5-11-33-18)23(35-21)30-22(32)19-12-16(25(26,27)28)8-9-20(19)34-15-17-6-4-10-29-17/h8-9,12,14,17-18,29H,4-7,10-11,13,15H2,1-3H3/b30-23-/t17-,18+/m0/s1
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4.60 -48.4n/an/an/an/an/a7.430



AbbVie Inc.

US Patent


Assay Description
HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...


US Patent US8846730 (2014)


BindingDB Entry DOI: 10.7270/Q2028Q6Q
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM133277
PNG
(US8846730, 24)
Show SMILES CN1CCC[C@H]1COc1ccc(cc1C(=O)\N=c1/sc(cn1C[C@H]1CCCO1)C(C)(C)C)C(F)(F)F
Show InChI InChI=1S/C26H34F3N3O3S/c1-25(2,3)22-15-32(14-19-8-6-12-34-19)24(36-22)30-23(33)20-13-17(26(27,28)29)9-10-21(20)35-16-18-7-5-11-31(18)4/h9-10,13,15,18-19H,5-8,11-12,14,16H2,1-4H3/b30-24-/t18-,19+/m0/s1
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4.60 -48.4n/an/an/an/an/a7.430



AbbVie Inc.

US Patent


Assay Description
HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...


US Patent US8846730 (2014)


BindingDB Entry DOI: 10.7270/Q2028Q6Q
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Rattus norvegicus (Rat))
BDBM133314
PNG
(US8846730, 80)
Show SMILES CC(=NOc1ccc(cc1C(=O)\N=c1/sc(cn1C[C@H]1CCCO1)C(C)(C)C)C(F)(F)F)C(F)(F)F |w:2.2|
Show InChI InChI=1S/C23H25F6N3O3S/c1-13(22(24,25)26)31-35-17-8-7-14(23(27,28)29)10-16(17)19(33)30-20-32(11-15-6-5-9-34-15)12-18(36-20)21(2,3)4/h7-8,10,12,15H,5-6,9,11H2,1-4H3/b30-20-,31-13+/t15-/m1/s1
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4.80 -48.3n/an/an/an/an/a7.430



AbbVie Inc.

US Patent


Assay Description
HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...


US Patent US8846730 (2014)


BindingDB Entry DOI: 10.7270/Q2028Q6Q
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM9880
PNG
(US8846730, 82)
Show SMILES CC(C)(C)CO\C=N\CCCOc1ccc(cc1C(=O)\N=c1/sc(cn1C[C@H]1CCCO1)C(C)(C)C)C(F)(F)F
Show InChI InChI=1S/C29H40F3N3O4S/c1-27(2,3)18-37-19-33-12-8-14-39-23-11-10-20(29(30,31)32)15-22(23)25(36)34-26-35(16-21-9-7-13-38-21)17-24(40-26)28(4,5)6/h10-11,15,17,19,21H,7-9,12-14,16,18H2,1-6H3/b33-19+,34-26-/t21-/m1/s1
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4.90 -48.2n/an/an/an/an/a7.430



AbbVie Inc.

US Patent


Assay Description
HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...


US Patent US8846730 (2014)


BindingDB Entry DOI: 10.7270/Q2028Q6Q
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Rattus norvegicus (Rat))
BDBM133273
PNG
(US8846730, 19)
Show SMILES CC(C)(C)c1cn(C[C@H]2CCCO2)\c(=N\C(=O)c2cc(ccc2OCc2cnccn2)C(F)(F)F)s1
Show InChI InChI=1S/C25H27F3N4O3S/c1-24(2,3)21-14-32(13-18-5-4-10-34-18)23(36-21)31-22(33)19-11-16(25(26,27)28)6-7-20(19)35-15-17-12-29-8-9-30-17/h6-9,11-12,14,18H,4-5,10,13,15H2,1-3H3/b31-23-/t18-/m1/s1
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US Patent
5 -48.2n/an/an/an/an/a7.430



AbbVie Inc.

US Patent


Assay Description
HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...


US Patent US8846730 (2014)


BindingDB Entry DOI: 10.7270/Q2028Q6Q
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM133273
PNG
(US8846730, 19)
Show SMILES CC(C)(C)c1cn(C[C@H]2CCCO2)\c(=N\C(=O)c2cc(ccc2OCc2cnccn2)C(F)(F)F)s1
Show InChI InChI=1S/C25H27F3N4O3S/c1-24(2,3)21-14-32(13-18-5-4-10-34-18)23(36-21)31-22(33)19-11-16(25(26,27)28)6-7-20(19)35-15-17-12-29-8-9-30-17/h6-9,11-12,14,18H,4-5,10,13,15H2,1-3H3/b31-23-/t18-/m1/s1
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5 -48.2n/an/an/an/an/a7.430



AbbVie Inc.

US Patent


Assay Description
HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...


US Patent US8846730 (2014)


BindingDB Entry DOI: 10.7270/Q2028Q6Q
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Rattus norvegicus (Rat))
BDBM133298
PNG
(US8846730, 56)
Show SMILES CC(C)(C)c1cn(C[C@H]2CCCO2)\c(=N\C(=O)c2cc(ccc2OCc2ccn[nH]2)C(F)(F)F)s1
Show InChI InChI=1S/C24H27F3N4O3S/c1-23(2,3)20-13-31(12-17-5-4-10-33-17)22(35-20)29-21(32)18-11-15(24(25,26)27)6-7-19(18)34-14-16-8-9-28-30-16/h6-9,11,13,17H,4-5,10,12,14H2,1-3H3,(H,28,30)/b29-22-/t17-/m1/s1
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US Patent
5.10 -48.1n/an/an/an/an/a7.430



AbbVie Inc.

US Patent


Assay Description
HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...


US Patent US8846730 (2014)


BindingDB Entry DOI: 10.7270/Q2028Q6Q
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Rattus norvegicus (Rat))
BDBM133303
PNG
(US8846730, 66)
Show SMILES CC(C)(C)c1cn(C[C@H]2CCCO2)\c(=N\C(=O)c2cc(ccc2OC[C@@H]2CNCCO2)C(F)(F)F)s1
Show InChI InChI=1S/C25H32F3N3O4S/c1-24(2,3)21-14-31(13-17-5-4-9-33-17)23(36-21)30-22(32)19-11-16(25(26,27)28)6-7-20(19)35-15-18-12-29-8-10-34-18/h6-7,11,14,17-18,29H,4-5,8-10,12-13,15H2,1-3H3/b30-23-/t17-,18+/m1/s1
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5.10 -48.1n/an/an/an/an/a7.430



AbbVie Inc.

US Patent


Assay Description
HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...


US Patent US8846730 (2014)


BindingDB Entry DOI: 10.7270/Q2028Q6Q
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Rattus norvegicus (Rat))
BDBM9842
PNG
(US8846730, 65 | US8846730, 76)
Show SMILES CC(C)(C)NOc1ccc(cc1C(=O)\N=c1/sc(cn1C[C@H]1CCCO1)C(C)(C)C)C(F)(F)F
Show InChI InChI=1S/C24H32F3N3O3S/c1-22(2,3)19-14-30(13-16-8-7-11-32-16)21(34-19)28-20(31)17-12-15(24(25,26)27)9-10-18(17)33-29-23(4,5)6/h9-10,12,14,16,29H,7-8,11,13H2,1-6H3/b28-21-/t16-/m1/s1
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5.20 -48.1n/an/an/an/an/a7.430



AbbVie Inc.

US Patent


Assay Description
HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...


US Patent US8846730 (2014)


BindingDB Entry DOI: 10.7270/Q2028Q6Q
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM133306
PNG
(US8846730, 71)
Show SMILES CC(C)(C)C(\COc1ccc(cc1C(=O)\N=c1/sc(cn1C[C@H]1CCCO1)C(C)(C)C)C(F)(F)F)=N/O
Show InChI InChI=1S/C26H34F3N3O4S/c1-24(2,3)20(31-34)15-36-19-10-9-16(26(27,28)29)12-18(19)22(33)30-23-32(13-17-8-7-11-35-17)14-21(37-23)25(4,5)6/h9-10,12,14,17,34H,7-8,11,13,15H2,1-6H3/b30-23-,31-20-/t17-/m1/s1
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5.40 -48.0n/an/an/an/an/a7.430



AbbVie Inc.

US Patent


Assay Description
HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...


US Patent US8846730 (2014)


BindingDB Entry DOI: 10.7270/Q2028Q6Q
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM133285
PNG
(US8846730, 38)
Show SMILES CC(C)(C)c1cn(C[C@H]2CCCO2)\c(=N\C(=O)c2cc(ccc2OCc2nccs2)C(F)(F)F)s1
Show InChI InChI=1S/C24H26F3N3O3S2/c1-23(2,3)19-13-30(12-16-5-4-9-32-16)22(35-19)29-21(31)17-11-15(24(25,26)27)6-7-18(17)33-14-20-28-8-10-34-20/h6-8,10-11,13,16H,4-5,9,12,14H2,1-3H3/b29-22-/t16-/m1/s1
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5.5 -47.9n/an/an/an/an/a7.430



AbbVie Inc.

US Patent


Assay Description
HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...


US Patent US8846730 (2014)


BindingDB Entry DOI: 10.7270/Q2028Q6Q
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM133283
PNG
(US8846730, 36)
Show SMILES CC(C)(C)c1cn(C[C@H]2CCCO2)\c(=N\C(=O)c2cc(ccc2OCc2ccccc2)C(F)(F)F)s1
Show InChI InChI=1S/C27H29F3N2O3S/c1-26(2,3)23-16-32(15-20-10-7-13-34-20)25(36-23)31-24(33)21-14-19(27(28,29)30)11-12-22(21)35-17-18-8-5-4-6-9-18/h4-6,8-9,11-12,14,16,20H,7,10,13,15,17H2,1-3H3/b31-25-/t20-/m1/s1
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6 -47.7n/an/an/an/an/a7.430



AbbVie Inc.

US Patent


Assay Description
HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...


US Patent US8846730 (2014)


BindingDB Entry DOI: 10.7270/Q2028Q6Q
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Rattus norvegicus (Rat))
BDBM50006285
PNG
(CHEMBL3234699 | US8846730, 18)
Show SMILES CC(C)(C)c1cn(C[C@H]2CCCO2)\c(=N\C(=O)c2cc(ccc2OCc2ccccn2)C(F)(F)F)s1 |r|
Show InChI InChI=1S/C26H28F3N3O3S/c1-25(2,3)22-15-32(14-19-8-6-12-34-19)24(36-22)31-23(33)20-13-17(26(27,28)29)9-10-21(20)35-16-18-7-4-5-11-30-18/h4-5,7,9-11,13,15,19H,6,8,12,14,16H2,1-3H3/b31-24-/t19-/m1/s1
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6 -47.7n/an/an/an/an/a7.430



AbbVie Inc.

US Patent


Assay Description
HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...


US Patent US8846730 (2014)


BindingDB Entry DOI: 10.7270/Q2028Q6Q
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Rattus norvegicus (Rat))
BDBM133282
PNG
(US8846730, 35)
Show SMILES CN(CCOc1ccc(cc1C(=O)\N=c1/sc(cn1C[C@H]1CCCO1)C(C)(C)C)C(F)(F)F)c1ccccc1
Show InChI InChI=1S/C29H34F3N3O3S/c1-28(2,3)25-19-35(18-22-11-8-15-37-22)27(39-25)33-26(36)23-17-20(29(30,31)32)12-13-24(23)38-16-14-34(4)21-9-6-5-7-10-21/h5-7,9-10,12-13,17,19,22H,8,11,14-16,18H2,1-4H3/b33-27-/t22-/m1/s1
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6.5 -47.5n/an/an/an/an/a7.430



AbbVie Inc.

US Patent


Assay Description
HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...


US Patent US8846730 (2014)


BindingDB Entry DOI: 10.7270/Q2028Q6Q
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Rattus norvegicus (Rat))
BDBM133309
PNG
(US8846730, 74)
Show SMILES CC(C)(C)c1cn(C[C@H]2CCCO2)\c(=N\C(=O)c2cc(ccc2OCC(C)(C)n2cccc2)C(F)(F)F)s1
Show InChI InChI=1S/C28H34F3N3O3S/c1-26(2,3)23-17-33(16-20-9-8-14-36-20)25(38-23)32-24(35)21-15-19(28(29,30)31)10-11-22(21)37-18-27(4,5)34-12-6-7-13-34/h6-7,10-13,15,17,20H,8-9,14,16,18H2,1-5H3/b32-25-/t20-/m1/s1
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6.60 -47.5n/an/an/an/an/a7.430



AbbVie Inc.

US Patent


Assay Description
HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...


US Patent US8846730 (2014)


BindingDB Entry DOI: 10.7270/Q2028Q6Q
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Rattus norvegicus (Rat))
BDBM9810
PNG
(US8846730, 63)
Show SMILES CC(C)(C)c1cn(C[C@H]2CCCO2)\c(=N\C(=O)c2cc(ccc2OCCC\N=C\OC2CCCCO2)C(F)(F)F)s1
Show InChI InChI=1S/C29H38F3N3O5S/c1-28(2,3)24-18-35(17-21-8-6-14-37-21)27(41-24)34-26(36)22-16-20(29(30,31)32)10-11-23(22)38-15-7-12-33-19-40-25-9-4-5-13-39-25/h10-11,16,18-19,21,25H,4-9,12-15,17H2,1-3H3/b33-19+,34-27-/t21-,25?/m1/s1
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6.60 -47.5n/an/an/an/an/a7.430



AbbVie Inc.

US Patent


Assay Description
HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...


US Patent US8846730 (2014)


BindingDB Entry DOI: 10.7270/Q2028Q6Q
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM133281
PNG
(US8846730, 33)
Show SMILES CC(C)(C)c1cn(C[C@@H]2CCCO2)\c(=N\C(=O)c2cc(ccc2OC[C@H](N)CO)C(F)(F)F)s1
Show InChI InChI=1S/C23H30F3N3O4S/c1-22(2,3)19-11-29(10-16-5-4-8-32-16)21(34-19)28-20(31)17-9-14(23(24,25)26)6-7-18(17)33-13-15(27)12-30/h6-7,9,11,15-16,30H,4-5,8,10,12-13,27H2,1-3H3/b28-21-/t15-,16+/m1/s1
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7.40 -47.2n/an/an/an/an/a7.430



AbbVie Inc.

US Patent


Assay Description
HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...


US Patent US8846730 (2014)


BindingDB Entry DOI: 10.7270/Q2028Q6Q
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM133266
PNG
(US8846730, 3)
Show SMILES CN1CC[C@H]1COc1ccc(cc1C(=O)\N=c1/sc(cn1C[C@H]1CCCO1)C(C)(C)C)C(F)(F)F
Show InChI InChI=1S/C25H32F3N3O3S/c1-24(2,3)21-14-31(13-18-6-5-11-33-18)23(35-21)29-22(32)19-12-16(25(26,27)28)7-8-20(19)34-15-17-9-10-30(17)4/h7-8,12,14,17-18H,5-6,9-11,13,15H2,1-4H3/b29-23-/t17-,18+/m0/s1
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7.40 -47.2n/an/an/an/an/a7.430



AbbVie Inc.

US Patent


Assay Description
HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...


US Patent US8846730 (2014)


BindingDB Entry DOI: 10.7270/Q2028Q6Q
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Rattus norvegicus (Rat))
BDBM133296
PNG
(US8846730, 55)
Show SMILES CN1CCC[C@H]1CNc1ccc(cc1C(=O)\N=c1/sc(cn1C[C@H]1CCCO1)C(C)(C)C)C(F)(F)F
Show InChI InChI=1S/C26H35F3N4O2S/c1-25(2,3)22-16-33(15-19-8-6-12-35-19)24(36-22)31-23(34)20-13-17(26(27,28)29)9-10-21(20)30-14-18-7-5-11-32(18)4/h9-10,13,16,18-19,30H,5-8,11-12,14-15H2,1-4H3/b31-24-/t18-,19+/m0/s1
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8.10 -47.0n/an/an/an/an/a7.430



AbbVie Inc.

US Patent


Assay Description
HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...


US Patent US8846730 (2014)


BindingDB Entry DOI: 10.7270/Q2028Q6Q
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Rattus norvegicus (Rat))
BDBM133305
PNG
(US8846730, 70)
Show SMILES CC(C)(C)C(\COc1ccc(cc1C(=O)\N=c1/sc(cn1C[C@H]1CCCO1)C(C)(C)C)C(F)(F)F)=N\O
Show InChI InChI=1S/C26H34F3N3O4S/c1-24(2,3)20(31-34)15-36-19-10-9-16(26(27,28)29)12-18(19)22(33)30-23-32(13-17-8-7-11-35-17)14-21(37-23)25(4,5)6/h9-10,12,14,17,34H,7-8,11,13,15H2,1-6H3/b30-23-,31-20+/t17-/m1/s1
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8.10 -47.0n/an/an/an/an/a7.430



AbbVie Inc.

US Patent


Assay Description
HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...


US Patent US8846730 (2014)


BindingDB Entry DOI: 10.7270/Q2028Q6Q
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM133291
PNG
(US8846730, 45)
Show SMILES CCN1CCC[C@H]1COc1ccc(cc1C(=O)\N=c1/sc(cn1C[C@H]1CCCO1)C(C)(C)C)C(F)(F)F
Show InChI InChI=1S/C27H36F3N3O3S/c1-5-32-12-6-8-19(32)17-36-22-11-10-18(27(28,29)30)14-21(22)24(34)31-25-33(15-20-9-7-13-35-20)16-23(37-25)26(2,3)4/h10-11,14,16,19-20H,5-9,12-13,15,17H2,1-4H3/b31-25-/t19-,20+/m0/s1
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8.20 -46.9n/an/an/an/an/a7.430



AbbVie Inc.

US Patent


Assay Description
HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...


US Patent US8846730 (2014)


BindingDB Entry DOI: 10.7270/Q2028Q6Q
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Rattus norvegicus (Rat))
BDBM133291
PNG
(US8846730, 45)
Show SMILES CCN1CCC[C@H]1COc1ccc(cc1C(=O)\N=c1/sc(cn1C[C@H]1CCCO1)C(C)(C)C)C(F)(F)F
Show InChI InChI=1S/C27H36F3N3O3S/c1-5-32-12-6-8-19(32)17-36-22-11-10-18(27(28,29)30)14-21(22)24(34)31-25-33(15-20-9-7-13-35-20)16-23(37-25)26(2,3)4/h10-11,14,16,19-20H,5-9,12-13,15,17H2,1-4H3/b31-25-/t19-,20+/m0/s1
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8.60 -46.8n/an/an/an/an/a7.430



AbbVie Inc.

US Patent


Assay Description
HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...


US Patent US8846730 (2014)


BindingDB Entry DOI: 10.7270/Q2028Q6Q
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Rattus norvegicus (Rat))
BDBM133284
PNG
(US8846730, 37)
Show SMILES CC(C)(C)c1cn(C[C@H]2CCCO2)\c(=N\C(=O)c2cc(ccc2OCc2cnco2)C(F)(F)F)s1
Show InChI InChI=1S/C24H26F3N3O4S/c1-23(2,3)20-12-30(11-16-5-4-8-32-16)22(35-20)29-21(31)18-9-15(24(25,26)27)6-7-19(18)33-13-17-10-28-14-34-17/h6-7,9-10,12,14,16H,4-5,8,11,13H2,1-3H3/b29-22-/t16-/m1/s1
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9 -46.7n/an/an/an/an/a7.430



AbbVie Inc.

US Patent


Assay Description
HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...


US Patent US8846730 (2014)


BindingDB Entry DOI: 10.7270/Q2028Q6Q
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Rattus norvegicus (Rat))
BDBM133301
PNG
(US8846730, 59)
Show SMILES CN1CCC[C@H]1COc1ccc(cc1C(=O)\N=c1/sc(cn1C[C@H]1CCCO1)C(C)(C)C)C#N
Show InChI InChI=1S/C26H34N4O3S/c1-26(2,3)23-16-30(15-20-8-6-12-32-20)25(34-23)28-24(31)21-13-18(14-27)9-10-22(21)33-17-19-7-5-11-29(19)4/h9-10,13,16,19-20H,5-8,11-12,15,17H2,1-4H3/b28-25-/t19-,20+/m0/s1
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9.40 -46.6n/an/an/an/an/a7.430



AbbVie Inc.

US Patent


Assay Description
HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...


US Patent US8846730 (2014)


BindingDB Entry DOI: 10.7270/Q2028Q6Q
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Rattus norvegicus (Rat))
BDBM133300
PNG
(US8846730, 58)
Show SMILES CC(C)(C)c1cn(C[C@H]2CCCO2)\c(=N\C(=O)c2cc(ccc2OCCNCCO)C(F)(F)F)s1
Show InChI InChI=1S/C24H32F3N3O4S/c1-23(2,3)20-15-30(14-17-5-4-11-33-17)22(35-20)29-21(32)18-13-16(24(25,26)27)6-7-19(18)34-12-9-28-8-10-31/h6-7,13,15,17,28,31H,4-5,8-12,14H2,1-3H3/b29-22-/t17-/m1/s1
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10 -46.4n/an/an/an/an/a7.430



AbbVie Inc.

US Patent


Assay Description
HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...


US Patent US8846730 (2014)


BindingDB Entry DOI: 10.7270/Q2028Q6Q
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Rattus norvegicus (Rat))
BDBM133274
PNG
(US8846730, 21)
Show SMILES CC(C)(C)c1cn(C[C@H]2CCCO2)\c(=N\C(=O)c2cc(ccc2OCc2cccnc2)C(F)(F)F)s1
Show InChI InChI=1S/C26H28F3N3O3S/c1-25(2,3)22-15-32(14-19-7-5-11-34-19)24(36-22)31-23(33)20-12-18(26(27,28)29)8-9-21(20)35-16-17-6-4-10-30-13-17/h4,6,8-10,12-13,15,19H,5,7,11,14,16H2,1-3H3/b31-24-/t19-/m1/s1
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10 -46.4n/an/an/an/an/a7.430



AbbVie Inc.

US Patent


Assay Description
HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...


US Patent US8846730 (2014)


BindingDB Entry DOI: 10.7270/Q2028Q6Q
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM133298
PNG
(US8846730, 56)
Show SMILES CC(C)(C)c1cn(C[C@H]2CCCO2)\c(=N\C(=O)c2cc(ccc2OCc2ccn[nH]2)C(F)(F)F)s1
Show InChI InChI=1S/C24H27F3N4O3S/c1-23(2,3)20-13-31(12-17-5-4-10-33-17)22(35-20)29-21(32)18-11-15(24(25,26)27)6-7-19(18)34-14-16-8-9-28-30-16/h6-9,11,13,17H,4-5,10,12,14H2,1-3H3,(H,28,30)/b29-22-/t17-/m1/s1
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11 -46.2n/an/an/an/an/a7.430



AbbVie Inc.

US Patent


Assay Description
HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...


US Patent US8846730 (2014)


BindingDB Entry DOI: 10.7270/Q2028Q6Q
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM133305
PNG
(US8846730, 70)
Show SMILES CC(C)(C)C(\COc1ccc(cc1C(=O)\N=c1/sc(cn1C[C@H]1CCCO1)C(C)(C)C)C(F)(F)F)=N\O
Show InChI InChI=1S/C26H34F3N3O4S/c1-24(2,3)20(31-34)15-36-19-10-9-16(26(27,28)29)12-18(19)22(33)30-23-32(13-17-8-7-11-35-17)14-21(37-23)25(4,5)6/h9-10,12,14,17,34H,7-8,11,13,15H2,1-6H3/b30-23-,31-20+/t17-/m1/s1
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12 -46.0n/an/an/an/an/a7.430



AbbVie Inc.

US Patent


Assay Description
HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...


US Patent US8846730 (2014)


BindingDB Entry DOI: 10.7270/Q2028Q6Q
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Rattus norvegicus (Rat))
BDBM9668
PNG
(US8846730, 49)
Show SMILES CC(C)(C)c1cn(C[C@H]2CCCO2)\c(=N\C(=O)c2cc(ccc2OC[C@H]2CCC[N+]2(C)[O-])C(F)(F)F)s1
Show InChI InChI=1S/C26H34F3N3O4S/c1-25(2,3)22-15-31(14-19-8-6-12-35-19)24(37-22)30-23(33)20-13-17(26(27,28)29)9-10-21(20)36-16-18-7-5-11-32(18,4)34/h9-10,13,15,18-19H,5-8,11-12,14,16H2,1-4H3/b30-24-/t18-,19-,32?/m1/s1
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12 -46.0n/an/an/an/an/a7.430



AbbVie Inc.

US Patent


Assay Description
HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...


US Patent US8846730 (2014)


BindingDB Entry DOI: 10.7270/Q2028Q6Q
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM133274
PNG
(US8846730, 21)
Show SMILES CC(C)(C)c1cn(C[C@H]2CCCO2)\c(=N\C(=O)c2cc(ccc2OCc2cccnc2)C(F)(F)F)s1
Show InChI InChI=1S/C26H28F3N3O3S/c1-25(2,3)22-15-32(14-19-7-5-11-34-19)24(36-22)31-23(33)20-12-18(26(27,28)29)8-9-21(20)35-16-17-6-4-10-30-13-17/h4,6,8-10,12-13,15,19H,5,7,11,14,16H2,1-3H3/b31-24-/t19-/m1/s1
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13 -45.8n/an/an/an/an/a7.430



AbbVie Inc.

US Patent


Assay Description
HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...


US Patent US8846730 (2014)


BindingDB Entry DOI: 10.7270/Q2028Q6Q
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Rattus norvegicus (Rat))
BDBM9655
PNG
(US8846730, 34)
Show SMILES CN1CCN(C)[C@@H](COc2ccc(cc2C(=O)\N=c2/sc(cn2C[C@H]2CCCO2)C(C)(C)C)C(F)(F)F)C1
Show InChI InChI=1S/C27H37F3N4O3S/c1-26(2,3)23-16-34(15-20-7-6-12-36-20)25(38-23)31-24(35)21-13-18(27(28,29)30)8-9-22(21)37-17-19-14-32(4)10-11-33(19)5/h8-9,13,16,19-20H,6-7,10-12,14-15,17H2,1-5H3/b31-25-/t19-,20-/m1/s1
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13 -45.8n/an/an/an/an/a7.430



AbbVie Inc.

US Patent


Assay Description
HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...


US Patent US8846730 (2014)


BindingDB Entry DOI: 10.7270/Q2028Q6Q
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Rattus norvegicus (Rat))
BDBM133304
PNG
(US8846730, 67)
Show SMILES Cn1cncc1COc1ccc(cc1C(=O)\N=c1/sc(cn1C[C@H]1CCCO1)C(C)(C)C)C(F)(F)F
Show InChI InChI=1S/C25H29F3N4O3S/c1-24(2,3)21-13-32(12-18-6-5-9-34-18)23(36-21)30-22(33)19-10-16(25(26,27)28)7-8-20(19)35-14-17-11-29-15-31(17)4/h7-8,10-11,13,15,18H,5-6,9,12,14H2,1-4H3/b30-23-/t18-/m1/s1
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13 -45.8n/an/an/an/an/a7.430



AbbVie Inc.

US Patent


Assay Description
HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...


US Patent US8846730 (2014)


BindingDB Entry DOI: 10.7270/Q2028Q6Q
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM133282
PNG
(US8846730, 35)
Show SMILES CN(CCOc1ccc(cc1C(=O)\N=c1/sc(cn1C[C@H]1CCCO1)C(C)(C)C)C(F)(F)F)c1ccccc1
Show InChI InChI=1S/C29H34F3N3O3S/c1-28(2,3)25-19-35(18-22-11-8-15-37-22)27(39-25)33-26(36)23-17-20(29(30,31)32)12-13-24(23)38-16-14-34(4)21-9-6-5-7-10-21/h5-7,9-10,12-13,17,19,22H,8,11,14-16,18H2,1-4H3/b33-27-/t22-/m1/s1
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14 -45.6n/an/an/an/an/a7.430



AbbVie Inc.

US Patent


Assay Description
HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...


US Patent US8846730 (2014)


BindingDB Entry DOI: 10.7270/Q2028Q6Q
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Rattus norvegicus (Rat))
BDBM133267
PNG
(US8846730, 6)
Show SMILES CC(C)(C)c1cn(C[C@H]2CCCO2)\c(=N\C(=O)c2cc(ccc2OC[C@H]2CCCCN2)C(F)(F)F)s1
Show InChI InChI=1S/C26H34F3N3O3S/c1-25(2,3)22-15-32(14-19-8-6-12-34-19)24(36-22)31-23(33)20-13-17(26(27,28)29)9-10-21(20)35-16-18-7-4-5-11-30-18/h9-10,13,15,18-19,30H,4-8,11-12,14,16H2,1-3H3/b31-24-/t18-,19-/m1/s1
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14 -45.6n/an/an/an/an/a7.430



AbbVie Inc.

US Patent


Assay Description
HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...


US Patent US8846730 (2014)


BindingDB Entry DOI: 10.7270/Q2028Q6Q
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Rattus norvegicus (Rat))
BDBM133288
PNG
(US8846730, 41)
Show SMILES COCCn1cc(s\c1=N/C(=O)c1cc(ccc1OCc1cnccn1)C(F)(F)F)C(C)(C)C
Show InChI InChI=1S/C23H25F3N4O3S/c1-22(2,3)19-13-30(9-10-32-4)21(34-19)29-20(31)17-11-15(23(24,25)26)5-6-18(17)33-14-16-12-27-7-8-28-16/h5-8,11-13H,9-10,14H2,1-4H3/b29-21-
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14 -45.6n/an/an/an/an/a7.430



AbbVie Inc.

US Patent


Assay Description
HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...


US Patent US8846730 (2014)


BindingDB Entry DOI: 10.7270/Q2028Q6Q
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM133265
PNG
(US8846730, 2)
Show SMILES CC(C)(C)c1cn(C[C@H]2CCCO2)\c(=N\C(=O)c2cc(ccc2OC[C@@H]2CCN2)C(F)(F)F)s1
Show InChI InChI=1S/C24H30F3N3O3S/c1-23(2,3)20-13-30(12-17-5-4-10-32-17)22(34-20)29-21(31)18-11-15(24(25,26)27)6-7-19(18)33-14-16-8-9-28-16/h6-7,11,13,16-17,28H,4-5,8-10,12,14H2,1-3H3/b29-22-/t16-,17+/m0/s1
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15 -45.4n/an/an/an/an/a7.430



AbbVie Inc.

US Patent


Assay Description
HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...


US Patent US8846730 (2014)


BindingDB Entry DOI: 10.7270/Q2028Q6Q
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Rattus norvegicus (Rat))
BDBM133272
PNG
(US8846730, 17)
Show SMILES Cn1ccnc1COc1ccc(cc1C(=O)\N=c1/sc(cn1C[C@H]1CCCO1)C(C)(C)C)C(F)(F)F
Show InChI InChI=1S/C25H29F3N4O3S/c1-24(2,3)20-14-32(13-17-6-5-11-34-17)23(36-20)30-22(33)18-12-16(25(26,27)28)7-8-19(18)35-15-21-29-9-10-31(21)4/h7-10,12,14,17H,5-6,11,13,15H2,1-4H3/b30-23-/t17-/m1/s1
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15 -45.4n/an/an/an/an/a7.430



AbbVie Inc.

US Patent


Assay Description
HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...


US Patent US8846730 (2014)


BindingDB Entry DOI: 10.7270/Q2028Q6Q
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Rattus norvegicus (Rat))
BDBM133264
PNG
(US8846730, 1)
Show SMILES CC(C)(C)c1cn(C[C@H]2CCCO2)\c(=N\C(=O)c2cc(ccc2OC[C@H]2CCN2)C(F)(F)F)s1
Show InChI InChI=1S/C24H30F3N3O3S/c1-23(2,3)20-13-30(12-17-5-4-10-32-17)22(34-20)29-21(31)18-11-15(24(25,26)27)6-7-19(18)33-14-16-8-9-28-16/h6-7,11,13,16-17,28H,4-5,8-10,12,14H2,1-3H3/b29-22-/t16-,17-/m1/s1
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15 -45.4n/an/an/an/an/a7.430



AbbVie Inc.

US Patent


Assay Description
HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...


US Patent US8846730 (2014)


BindingDB Entry DOI: 10.7270/Q2028Q6Q
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Rattus norvegicus (Rat))
BDBM133299
PNG
(US8846730, 57)
Show SMILES CN1CCC[C@H]1COc1ccc(cc1C(=O)\N=c1/scc(n1C[C@H]1CCCO1)C(C)(C)C)C(F)(F)F
Show InChI InChI=1S/C26H34F3N3O3S/c1-25(2,3)22-16-36-24(32(22)14-19-8-6-12-34-19)30-23(33)20-13-17(26(27,28)29)9-10-21(20)35-15-18-7-5-11-31(18)4/h9-10,13,16,18-19H,5-8,11-12,14-15H2,1-4H3/b30-24-/t18-,19+/m0/s1
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15 -45.4n/an/an/an/an/a7.430



AbbVie Inc.

US Patent


Assay Description
HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...


US Patent US8846730 (2014)


BindingDB Entry DOI: 10.7270/Q2028Q6Q
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM133293
PNG
(US8846730, 48)
Show SMILES CC(C)(C)c1cn(C[C@H]2CCCO2)\c(=N\C(=O)c2cc(ccc2OC[C@@H]2CCCN2S(C)(=O)=O)C(F)(F)F)s1
Show InChI InChI=1S/C26H34F3N3O5S2/c1-25(2,3)22-15-31(14-19-8-6-12-36-19)24(38-22)30-23(33)20-13-17(26(27,28)29)9-10-21(20)37-16-18-7-5-11-32(18)39(4,34)35/h9-10,13,15,18-19H,5-8,11-12,14,16H2,1-4H3/b30-24-/t18-,19+/m0/s1
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16 -45.2n/an/an/an/an/a7.430



AbbVie Inc.

US Patent


Assay Description
HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...


US Patent US8846730 (2014)


BindingDB Entry DOI: 10.7270/Q2028Q6Q
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Rattus norvegicus (Rat))
BDBM133269
PNG
(US8846730, 8)
Show SMILES CN1CC[C@@H]1COc1ccc(cc1C(=O)\N=c1/sc(cn1C[C@H]1CCCO1)C(C)(C)C)C(F)(F)F
Show InChI InChI=1S/C25H32F3N3O3S/c1-24(2,3)21-14-31(13-18-6-5-11-33-18)23(35-21)29-22(32)19-12-16(25(26,27)28)7-8-20(19)34-15-17-9-10-30(17)4/h7-8,12,14,17-18H,5-6,9-11,13,15H2,1-4H3/b29-23-/t17-,18-/m1/s1
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17 -45.1n/an/an/an/an/a7.430



AbbVie Inc.

US Patent


Assay Description
HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...


US Patent US8846730 (2014)


BindingDB Entry DOI: 10.7270/Q2028Q6Q
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Rattus norvegicus (Rat))
BDBM133268
PNG
(US8846730, 7)
Show SMILES CN1CCCC[C@@H]1COc1ccc(cc1C(=O)\N=c1/sc(cn1C[C@H]1CCCO1)C(C)(C)C)C(F)(F)F
Show InChI InChI=1S/C27H36F3N3O3S/c1-26(2,3)23-16-33(15-20-9-7-13-35-20)25(37-23)31-24(34)21-14-18(27(28,29)30)10-11-22(21)36-17-19-8-5-6-12-32(19)4/h10-11,14,16,19-20H,5-9,12-13,15,17H2,1-4H3/b31-25-/t19-,20-/m1/s1
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19 -44.8n/an/an/an/an/a7.430



AbbVie Inc.

US Patent


Assay Description
HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...


US Patent US8846730 (2014)


BindingDB Entry DOI: 10.7270/Q2028Q6Q
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM9842
PNG
(US8846730, 65 | US8846730, 76)
Show SMILES CC(C)(C)NOc1ccc(cc1C(=O)\N=c1/sc(cn1C[C@H]1CCCO1)C(C)(C)C)C(F)(F)F
Show InChI InChI=1S/C24H32F3N3O3S/c1-22(2,3)19-14-30(13-16-8-7-11-32-16)21(34-19)28-20(31)17-12-15(24(25,26)27)9-10-18(17)33-29-23(4,5)6/h9-10,12,14,16,29H,7-8,11,13H2,1-6H3/b28-21-/t16-/m1/s1
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20 -44.7n/an/an/an/an/a7.430



AbbVie Inc.

US Patent


Assay Description
HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...


US Patent US8846730 (2014)


BindingDB Entry DOI: 10.7270/Q2028Q6Q
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM50006285
PNG
(CHEMBL3234699 | US8846730, 18)
Show SMILES CC(C)(C)c1cn(C[C@H]2CCCO2)\c(=N\C(=O)c2cc(ccc2OCc2ccccn2)C(F)(F)F)s1 |r|
Show InChI InChI=1S/C26H28F3N3O3S/c1-25(2,3)22-15-32(14-19-8-6-12-34-19)24(36-22)31-23(33)20-13-17(26(27,28)29)9-10-21(20)35-16-18-7-4-5-11-30-18/h4-5,7,9-11,13,15,19H,6,8,12,14,16H2,1-3H3/b31-24-/t19-/m1/s1
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20 -44.7n/an/an/an/an/a7.430



AbbVie Inc.

US Patent


Assay Description
HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...


US Patent US8846730 (2014)


BindingDB Entry DOI: 10.7270/Q2028Q6Q
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM133303
PNG
(US8846730, 66)
Show SMILES CC(C)(C)c1cn(C[C@H]2CCCO2)\c(=N\C(=O)c2cc(ccc2OC[C@@H]2CNCCO2)C(F)(F)F)s1
Show InChI InChI=1S/C25H32F3N3O4S/c1-24(2,3)21-14-31(13-17-5-4-9-33-17)23(36-21)30-22(32)19-11-16(25(26,27)28)6-7-20(19)35-15-18-12-29-8-10-34-18/h6-7,11,14,17-18,29H,4-5,8-10,12-13,15H2,1-3H3/b30-23-/t17-,18+/m1/s1
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21 -44.6n/an/an/an/an/a7.430



AbbVie Inc.

US Patent


Assay Description
HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...


US Patent US8846730 (2014)


BindingDB Entry DOI: 10.7270/Q2028Q6Q
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Rattus norvegicus (Rat))
BDBM133292
PNG
(US8846730, 46)
Show SMILES CC(C)N1CCC[C@H]1COc1ccc(cc1C(=O)\N=c1/sc(cn1C[C@H]1CCCO1)C(C)(C)C)C(F)(F)F
Show InChI InChI=1S/C28H38F3N3O3S/c1-18(2)34-12-6-8-20(34)17-37-23-11-10-19(28(29,30)31)14-22(23)25(35)32-26-33(15-21-9-7-13-36-21)16-24(38-26)27(3,4)5/h10-11,14,16,18,20-21H,6-9,12-13,15,17H2,1-5H3/b32-26-/t20-,21+/m0/s1
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21 -44.6n/an/an/an/an/a7.430



AbbVie Inc.

US Patent


Assay Description
HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...


US Patent US8846730 (2014)


BindingDB Entry DOI: 10.7270/Q2028Q6Q
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM133312
PNG
(US8846730, 78)
Show SMILES CCN(CC)Oc1ccc(cc1C(=O)\N=c1/sc(cn1C[C@H]1CCCO1)C(C)(C)C)C(F)(F)F
Show InChI InChI=1S/C24H32F3N3O3S/c1-6-30(7-2)33-19-11-10-16(24(25,26)27)13-18(19)21(31)28-22-29(14-17-9-8-12-32-17)15-20(34-22)23(3,4)5/h10-11,13,15,17H,6-9,12,14H2,1-5H3/b28-22-/t17-/m1/s1
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22 -44.4n/an/an/an/an/a7.430



AbbVie Inc.

US Patent


Assay Description
HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...


US Patent US8846730 (2014)


BindingDB Entry DOI: 10.7270/Q2028Q6Q
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM9668
PNG
(US8846730, 49)
Show SMILES CC(C)(C)c1cn(C[C@H]2CCCO2)\c(=N\C(=O)c2cc(ccc2OC[C@H]2CCC[N+]2(C)[O-])C(F)(F)F)s1
Show InChI InChI=1S/C26H34F3N3O4S/c1-25(2,3)22-15-31(14-19-8-6-12-35-19)24(37-22)30-23(33)20-13-17(26(27,28)29)9-10-21(20)36-16-18-7-5-11-32(18,4)34/h9-10,13,15,18-19H,5-8,11-12,14,16H2,1-4H3/b30-24-/t18-,19-,32?/m1/s1
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24 -44.2n/an/an/an/an/a7.430



AbbVie Inc.

US Patent


Assay Description
HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...


US Patent US8846730 (2014)


BindingDB Entry DOI: 10.7270/Q2028Q6Q
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Rattus norvegicus (Rat))
BDBM9658
PNG
(US8846730, 47)
Show SMILES CC(=O)N1CCC[C@@H]1COc1ccc(cc1C(=O)\N=c1/sc(cn1C[C@H]1CCCO1)C(C)(C)C)C(F)(F)F
Show InChI InChI=1S/C27H34F3N3O4S/c1-17(34)33-11-5-7-19(33)16-37-22-10-9-18(27(28,29)30)13-21(22)24(35)31-25-32(14-20-8-6-12-36-20)15-23(38-25)26(2,3)4/h9-10,13,15,19-20H,5-8,11-12,14,16H2,1-4H3/b31-25-/t19-,20-/m1/s1
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24 -44.2n/an/an/an/an/a7.430



AbbVie Inc.

US Patent


Assay Description
HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...


US Patent US8846730 (2014)


BindingDB Entry DOI: 10.7270/Q2028Q6Q
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM9655
PNG
(US8846730, 34)
Show SMILES CN1CCN(C)[C@@H](COc2ccc(cc2C(=O)\N=c2/sc(cn2C[C@H]2CCCO2)C(C)(C)C)C(F)(F)F)C1
Show InChI InChI=1S/C27H37F3N4O3S/c1-26(2,3)23-16-34(15-20-7-6-12-36-20)25(38-23)31-24(35)21-13-18(27(28,29)30)8-9-22(21)37-17-19-14-32(4)10-11-33(19)5/h8-9,13,16,19-20H,6-7,10-12,14-15,17H2,1-5H3/b31-25-/t19-,20-/m1/s1
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25 -44.1n/an/an/an/an/a7.430



AbbVie Inc.

US Patent


Assay Description
HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...


US Patent US8846730 (2014)


BindingDB Entry DOI: 10.7270/Q2028Q6Q
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM9810
PNG
(US8846730, 63)
Show SMILES CC(C)(C)c1cn(C[C@H]2CCCO2)\c(=N\C(=O)c2cc(ccc2OCCC\N=C\OC2CCCCO2)C(F)(F)F)s1
Show InChI InChI=1S/C29H38F3N3O5S/c1-28(2,3)24-18-35(17-21-8-6-14-37-21)27(41-24)34-26(36)22-16-20(29(30,31)32)10-11-23(22)38-15-7-12-33-19-40-25-9-4-5-13-39-25/h10-11,16,18-19,21,25H,4-9,12-15,17H2,1-3H3/b33-19+,34-27-/t21-,25?/m1/s1
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25 -44.1n/an/an/an/an/a7.430



AbbVie Inc.

US Patent


Assay Description
HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...


US Patent US8846730 (2014)


BindingDB Entry DOI: 10.7270/Q2028Q6Q
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM133284
PNG
(US8846730, 37)
Show SMILES CC(C)(C)c1cn(C[C@H]2CCCO2)\c(=N\C(=O)c2cc(ccc2OCc2cnco2)C(F)(F)F)s1
Show InChI InChI=1S/C24H26F3N3O4S/c1-23(2,3)20-12-30(11-16-5-4-8-32-16)22(35-20)29-21(31)18-9-15(24(25,26)27)6-7-19(18)33-13-17-10-28-14-34-17/h6-7,9-10,12,14,16H,4-5,8,11,13H2,1-3H3/b29-22-/t16-/m1/s1
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26 -44.0n/an/an/an/an/a7.430



AbbVie Inc.

US Patent


Assay Description
HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...


US Patent US8846730 (2014)


BindingDB Entry DOI: 10.7270/Q2028Q6Q
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Rattus norvegicus (Rat))
BDBM133270
PNG
(US8846730, 12)
Show SMILES CN1CC(COc2ccc(cc2C(=O)\N=c2/sc(cn2C[C@H]2CCCO2)C(C)(C)C)C(F)(F)F)C1
Show InChI InChI=1S/C25H32F3N3O3S/c1-24(2,3)21-14-31(13-18-6-5-9-33-18)23(35-21)29-22(32)19-10-17(25(26,27)28)7-8-20(19)34-15-16-11-30(4)12-16/h7-8,10,14,16,18H,5-6,9,11-13,15H2,1-4H3/b29-23-/t18-/m1/s1
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28 -43.8n/an/an/an/an/a7.430



AbbVie Inc.

US Patent


Assay Description
HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...


US Patent US8846730 (2014)


BindingDB Entry DOI: 10.7270/Q2028Q6Q
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Rattus norvegicus (Rat))
BDBM133279
PNG
(US8846730, 30)
Show SMILES CN1CC[C@@H](COc2ccc(cc2C(=O)\N=c2/sc(cn2C[C@H]2CCCO2)C(C)(C)C)C(F)(F)F)C1
Show InChI InChI=1S/C26H34F3N3O3S/c1-25(2,3)22-15-32(14-19-6-5-11-34-19)24(36-22)30-23(33)20-12-18(26(27,28)29)7-8-21(20)35-16-17-9-10-31(4)13-17/h7-8,12,15,17,19H,5-6,9-11,13-14,16H2,1-4H3/b30-24-/t17-,19-/m1/s1
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29 -43.7n/an/an/an/an/a7.430



AbbVie Inc.

US Patent


Assay Description
HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...


US Patent US8846730 (2014)


BindingDB Entry DOI: 10.7270/Q2028Q6Q
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM133267
PNG
(US8846730, 6)
Show SMILES CC(C)(C)c1cn(C[C@H]2CCCO2)\c(=N\C(=O)c2cc(ccc2OC[C@H]2CCCCN2)C(F)(F)F)s1
Show InChI InChI=1S/C26H34F3N3O3S/c1-25(2,3)22-15-32(14-19-8-6-12-34-19)24(36-22)31-23(33)20-13-17(26(27,28)29)9-10-21(20)35-16-18-7-4-5-11-30-18/h9-10,13,15,18-19,30H,4-8,11-12,14,16H2,1-3H3/b31-24-/t18-,19-/m1/s1
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30 -43.7n/an/an/an/an/a7.430



AbbVie Inc.

US Patent


Assay Description
HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...


US Patent US8846730 (2014)


BindingDB Entry DOI: 10.7270/Q2028Q6Q
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM133268
PNG
(US8846730, 7)
Show SMILES CN1CCCC[C@@H]1COc1ccc(cc1C(=O)\N=c1/sc(cn1C[C@H]1CCCO1)C(C)(C)C)C(F)(F)F
Show InChI InChI=1S/C27H36F3N3O3S/c1-26(2,3)23-16-33(15-20-9-7-13-35-20)25(37-23)31-24(34)21-14-18(27(28,29)30)10-11-22(21)36-17-19-8-5-6-12-32(19)4/h10-11,14,16,19-20H,5-9,12-13,15,17H2,1-4H3/b31-25-/t19-,20-/m1/s1
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33 -43.4n/an/an/an/an/a7.430



AbbVie Inc.

US Patent


Assay Description
HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...


US Patent US8846730 (2014)


BindingDB Entry DOI: 10.7270/Q2028Q6Q
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM133300
PNG
(US8846730, 58)
Show SMILES CC(C)(C)c1cn(C[C@H]2CCCO2)\c(=N\C(=O)c2cc(ccc2OCCNCCO)C(F)(F)F)s1
Show InChI InChI=1S/C24H32F3N3O4S/c1-23(2,3)20-15-30(14-17-5-4-11-33-17)22(35-20)29-21(32)18-13-16(24(25,26)27)6-7-19(18)34-12-9-28-8-10-31/h6-7,13,15,17,28,31H,4-5,8-12,14H2,1-3H3/b29-22-/t17-/m1/s1
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34 -43.3n/an/an/an/an/a7.430



AbbVie Inc.

US Patent


Assay Description
HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...


US Patent US8846730 (2014)


BindingDB Entry DOI: 10.7270/Q2028Q6Q
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM133309
PNG
(US8846730, 74)
Show SMILES CC(C)(C)c1cn(C[C@H]2CCCO2)\c(=N\C(=O)c2cc(ccc2OCC(C)(C)n2cccc2)C(F)(F)F)s1
Show InChI InChI=1S/C28H34F3N3O3S/c1-26(2,3)23-17-33(16-20-9-8-14-36-20)25(38-23)32-24(35)21-15-19(28(29,30)31)10-11-22(21)37-18-27(4,5)34-12-6-7-13-34/h6-7,10-13,15,17,20H,8-9,14,16,18H2,1-5H3/b32-25-/t20-/m1/s1
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34 -43.3n/an/an/an/an/a7.430



AbbVie Inc.

US Patent


Assay Description
HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...


US Patent US8846730 (2014)


BindingDB Entry DOI: 10.7270/Q2028Q6Q
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM133296
PNG
(US8846730, 55)
Show SMILES CN1CCC[C@H]1CNc1ccc(cc1C(=O)\N=c1/sc(cn1C[C@H]1CCCO1)C(C)(C)C)C(F)(F)F
Show InChI InChI=1S/C26H35F3N4O2S/c1-25(2,3)22-16-33(15-19-8-6-12-35-19)24(36-22)31-23(34)20-13-17(26(27,28)29)9-10-21(20)30-14-18-7-5-11-32(18)4/h9-10,13,16,18-19,30H,5-8,11-12,14-15H2,1-4H3/b31-24-/t18-,19+/m0/s1
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36 -43.2n/an/an/an/an/a7.430



AbbVie Inc.

US Patent


Assay Description
HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...


US Patent US8846730 (2014)


BindingDB Entry DOI: 10.7270/Q2028Q6Q
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM133301
PNG
(US8846730, 59)
Show SMILES CN1CCC[C@H]1COc1ccc(cc1C(=O)\N=c1/sc(cn1C[C@H]1CCCO1)C(C)(C)C)C#N
Show InChI InChI=1S/C26H34N4O3S/c1-26(2,3)23-16-30(15-20-8-6-12-32-20)25(34-23)28-24(31)21-13-18(14-27)9-10-22(21)33-17-19-7-5-11-29(19)4/h9-10,13,16,19-20H,5-8,11-12,15,17H2,1-4H3/b28-25-/t19-,20+/m0/s1
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US Patent
43 -42.8n/an/an/an/an/a7.430



AbbVie Inc.

US Patent


Assay Description
HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...


US Patent US8846730 (2014)


BindingDB Entry DOI: 10.7270/Q2028Q6Q
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM133288
PNG
(US8846730, 41)
Show SMILES COCCn1cc(s\c1=N/C(=O)c1cc(ccc1OCc1cnccn1)C(F)(F)F)C(C)(C)C
Show InChI InChI=1S/C23H25F3N4O3S/c1-22(2,3)19-13-30(9-10-32-4)21(34-19)29-20(31)17-11-15(23(24,25)26)5-6-18(17)33-14-16-12-27-7-8-28-16/h5-8,11-13H,9-10,14H2,1-4H3/b29-21-
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US Patent
45 -42.6n/an/an/an/an/a7.430



AbbVie Inc.

US Patent


Assay Description
HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...


US Patent US8846730 (2014)


BindingDB Entry DOI: 10.7270/Q2028Q6Q
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM133269
PNG
(US8846730, 8)
Show SMILES CN1CC[C@@H]1COc1ccc(cc1C(=O)\N=c1/sc(cn1C[C@H]1CCCO1)C(C)(C)C)C(F)(F)F
Show InChI InChI=1S/C25H32F3N3O3S/c1-24(2,3)21-14-31(13-18-6-5-11-33-18)23(35-21)29-22(32)19-12-16(25(26,27)28)7-8-20(19)34-15-17-9-10-30(17)4/h7-8,12,14,17-18H,5-6,9-11,13,15H2,1-4H3/b29-23-/t17-,18-/m1/s1
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47 -42.5n/an/an/an/an/a7.430



AbbVie Inc.

US Patent


Assay Description
HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...


US Patent US8846730 (2014)


BindingDB Entry DOI: 10.7270/Q2028Q6Q
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Rattus norvegicus (Rat))
BDBM9654
PNG
(US8846730, 20)
Show SMILES CC(C)(C)c1cn(C[C@H]2CCCO2)\c(=N\C(=O)c2cc(ccc2OCc2cccc[n+]2[O-])C(F)(F)F)s1
Show InChI InChI=1S/C26H28F3N3O4S/c1-25(2,3)22-15-31(14-19-8-6-12-35-19)24(37-22)30-23(33)20-13-17(26(27,28)29)9-10-21(20)36-16-18-7-4-5-11-32(18)34/h4-5,7,9-11,13,15,19H,6,8,12,14,16H2,1-3H3/b30-24-/t19-/m1/s1
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51 -42.3n/an/an/an/an/a7.430



AbbVie Inc.

US Patent


Assay Description
HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...


US Patent US8846730 (2014)


BindingDB Entry DOI: 10.7270/Q2028Q6Q
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM133272
PNG
(US8846730, 17)
Show SMILES Cn1ccnc1COc1ccc(cc1C(=O)\N=c1/sc(cn1C[C@H]1CCCO1)C(C)(C)C)C(F)(F)F
Show InChI InChI=1S/C25H29F3N4O3S/c1-24(2,3)20-14-32(13-17-6-5-11-34-17)23(36-20)30-22(33)18-12-16(25(26,27)28)7-8-19(18)35-15-21-29-9-10-31(21)4/h7-10,12,14,17H,5-6,11,13,15H2,1-4H3/b30-23-/t17-/m1/s1
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53 -42.2n/an/an/an/an/a7.430



AbbVie Inc.

US Patent


Assay Description
HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...


US Patent US8846730 (2014)


BindingDB Entry DOI: 10.7270/Q2028Q6Q
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM133289
PNG
(US8846730, 43)
Show SMILES CN1[C@H](COc2ccc(cc2C(=O)\N=c2/sc(cn2C[C@H]2CCCO2)C(C)(C)C)C(F)(F)F)CCC1=O
Show InChI InChI=1S/C26H32F3N3O4S/c1-25(2,3)21-14-32(13-18-6-5-11-35-18)24(37-21)30-23(34)19-12-16(26(27,28)29)7-9-20(19)36-15-17-8-10-22(33)31(17)4/h7,9,12,14,17-18H,5-6,8,10-11,13,15H2,1-4H3/b30-24-/t17-,18+/m0/s1
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62 -41.8n/an/an/an/an/a7.430



AbbVie Inc.

US Patent


Assay Description
HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...


US Patent US8846730 (2014)


BindingDB Entry DOI: 10.7270/Q2028Q6Q
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Rattus norvegicus (Rat))
BDBM133311
PNG
(US8846730, 77)
Show SMILES CC(CN1CCC[C@H]1COc1ccc(cc1C(=O)\N=c1/sc(cn1C[C@H]1CCCO1)C(C)(C)C)C(F)(F)F)=NO |w:38.42|
Show InChI InChI=1S/C28H37F3N4O4S/c1-18(33-37)14-34-11-5-7-20(34)17-39-23-10-9-19(28(29,30)31)13-22(23)25(36)32-26-35(15-21-8-6-12-38-21)16-24(40-26)27(2,3)4/h9-10,13,16,20-21,37H,5-8,11-12,14-15,17H2,1-4H3/b32-26-,33-18+/t20-,21+/m0/s1
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64 -41.7n/an/an/an/an/a7.430



AbbVie Inc.

US Patent


Assay Description
HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...


US Patent US8846730 (2014)


BindingDB Entry DOI: 10.7270/Q2028Q6Q
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Rattus norvegicus (Rat))
BDBM133278
PNG
(US8846730, 26)
Show SMILES CN1CCC[C@@H]1COc1ccc(cc1C(=O)\N=c1/sc(cn1C[C@H]1CCCO1)C(C)(C)C)C(F)(F)F
Show InChI InChI=1S/C26H34F3N3O3S/c1-25(2,3)22-15-32(14-19-8-6-12-34-19)24(36-22)30-23(33)20-13-17(26(27,28)29)9-10-21(20)35-16-18-7-5-11-31(18)4/h9-10,13,15,18-19H,5-8,11-12,14,16H2,1-4H3/b30-24-/t18-,19-/m1/s1
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70 -41.5n/an/an/an/an/a7.430



AbbVie Inc.

US Patent


Assay Description
HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...


US Patent US8846730 (2014)


BindingDB Entry DOI: 10.7270/Q2028Q6Q
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Rattus norvegicus (Rat))
BDBM133271
PNG
(US8846730, 15)
Show SMILES CN1CCC(COc2ccc(cc2C(=O)\N=c2/sc(cn2C[C@H]2CCCO2)C(C)(C)C)C(F)(F)F)CC1
Show InChI InChI=1S/C27H36F3N3O3S/c1-26(2,3)23-16-33(15-20-6-5-13-35-20)25(37-23)31-24(34)21-14-19(27(28,29)30)7-8-22(21)36-17-18-9-11-32(4)12-10-18/h7-8,14,16,18,20H,5-6,9-13,15,17H2,1-4H3/b31-25-/t20-/m1/s1
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83 -41.1n/an/an/an/an/a7.430



AbbVie Inc.

US Patent


Assay Description
HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...


US Patent US8846730 (2014)


BindingDB Entry DOI: 10.7270/Q2028Q6Q
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Rattus norvegicus (Rat))
BDBM133280
PNG
(US8846730, 31)
Show SMILES CN1CC[C@H](COc2ccc(cc2C(=O)\N=c2/sc(cn2C[C@H]2CCCO2)C(C)(C)C)C(F)(F)F)C1
Show InChI InChI=1S/C26H34F3N3O3S/c1-25(2,3)22-15-32(14-19-6-5-11-34-19)24(36-22)30-23(33)20-12-18(26(27,28)29)7-8-21(20)35-16-17-9-10-31(4)13-17/h7-8,12,15,17,19H,5-6,9-11,13-14,16H2,1-4H3/b30-24-/t17-,19+/m0/s1
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84 -41.1n/an/an/an/an/a7.430



AbbVie Inc.

US Patent


Assay Description
HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...


US Patent US8846730 (2014)


BindingDB Entry DOI: 10.7270/Q2028Q6Q
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM133311
PNG
(US8846730, 77)
Show SMILES CC(CN1CCC[C@H]1COc1ccc(cc1C(=O)\N=c1/sc(cn1C[C@H]1CCCO1)C(C)(C)C)C(F)(F)F)=NO |w:38.42|
Show InChI InChI=1S/C28H37F3N4O4S/c1-18(33-37)14-34-11-5-7-20(34)17-39-23-10-9-19(28(29,30)31)13-22(23)25(36)32-26-35(15-21-8-6-12-38-21)16-24(40-26)27(2,3)4/h9-10,13,16,20-21,37H,5-8,11-12,14-15,17H2,1-4H3/b32-26-,33-18+/t20-,21+/m0/s1
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85 -41.0n/an/an/an/an/a7.430



AbbVie Inc.

US Patent


Assay Description
HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...


US Patent US8846730 (2014)


BindingDB Entry DOI: 10.7270/Q2028Q6Q
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM133280
PNG
(US8846730, 31)
Show SMILES CN1CC[C@H](COc2ccc(cc2C(=O)\N=c2/sc(cn2C[C@H]2CCCO2)C(C)(C)C)C(F)(F)F)C1
Show InChI InChI=1S/C26H34F3N3O3S/c1-25(2,3)22-15-32(14-19-6-5-11-34-19)24(36-22)30-23(33)20-12-18(26(27,28)29)7-8-21(20)35-16-17-9-10-31(4)13-17/h7-8,12,15,17,19H,5-6,9-11,13-14,16H2,1-4H3/b30-24-/t17-,19+/m0/s1
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92 -40.8n/an/an/an/an/a7.430



AbbVie Inc.

US Patent


Assay Description
HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...


US Patent US8846730 (2014)


BindingDB Entry DOI: 10.7270/Q2028Q6Q
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM133292
PNG
(US8846730, 46)
Show SMILES CC(C)N1CCC[C@H]1COc1ccc(cc1C(=O)\N=c1/sc(cn1C[C@H]1CCCO1)C(C)(C)C)C(F)(F)F
Show InChI InChI=1S/C28H38F3N3O3S/c1-18(2)34-12-6-8-20(34)17-37-23-11-10-19(28(29,30)31)14-22(23)25(35)32-26-33(15-21-9-7-13-36-21)16-24(38-26)27(3,4)5/h10-11,14,16,18,20-21H,6-9,12-13,15,17H2,1-5H3/b32-26-/t20-,21+/m0/s1
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102 -40.6n/an/an/an/an/a7.430



AbbVie Inc.

US Patent


Assay Description
HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...


US Patent US8846730 (2014)


BindingDB Entry DOI: 10.7270/Q2028Q6Q
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM9658
PNG
(US8846730, 47)
Show SMILES CC(=O)N1CCC[C@@H]1COc1ccc(cc1C(=O)\N=c1/sc(cn1C[C@H]1CCCO1)C(C)(C)C)C(F)(F)F
Show InChI InChI=1S/C27H34F3N3O4S/c1-17(34)33-11-5-7-19(33)16-37-22-10-9-18(27(28,29)30)13-21(22)24(35)31-25-32(14-20-8-6-12-36-20)15-23(38-25)26(2,3)4/h9-10,13,15,19-20H,5-8,11-12,14,16H2,1-4H3/b31-25-/t19-,20-/m1/s1
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107 -40.5n/an/an/an/an/a7.430



AbbVie Inc.

US Patent


Assay Description
HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...


US Patent US8846730 (2014)


BindingDB Entry DOI: 10.7270/Q2028Q6Q
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM133264
PNG
(US8846730, 1)
Show SMILES CC(C)(C)c1cn(C[C@H]2CCCO2)\c(=N\C(=O)c2cc(ccc2OC[C@H]2CCN2)C(F)(F)F)s1
Show InChI InChI=1S/C24H30F3N3O3S/c1-23(2,3)20-13-30(12-17-5-4-10-32-17)22(34-20)29-21(31)18-11-15(24(25,26)27)6-7-19(18)33-14-16-8-9-28-16/h6-7,11,13,16-17,28H,4-5,8-10,12,14H2,1-3H3/b29-22-/t16-,17-/m1/s1
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115 -40.3n/an/an/an/an/a7.430



AbbVie Inc.

US Patent


Assay Description
HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...


US Patent US8846730 (2014)


BindingDB Entry DOI: 10.7270/Q2028Q6Q
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM133304
PNG
(US8846730, 67)
Show SMILES Cn1cncc1COc1ccc(cc1C(=O)\N=c1/sc(cn1C[C@H]1CCCO1)C(C)(C)C)C(F)(F)F
Show InChI InChI=1S/C25H29F3N4O3S/c1-24(2,3)21-13-32(12-18-6-5-9-34-18)23(36-21)30-22(33)19-10-16(25(26,27)28)7-8-20(19)35-14-17-11-29-15-31(17)4/h7-8,10-11,13,15,18H,5-6,9,12,14H2,1-4H3/b30-23-/t18-/m1/s1
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115 -40.3n/an/an/an/an/a7.430



AbbVie Inc.

US Patent


Assay Description
HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...


US Patent US8846730 (2014)


BindingDB Entry DOI: 10.7270/Q2028Q6Q
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM133279
PNG
(US8846730, 30)
Show SMILES CN1CC[C@@H](COc2ccc(cc2C(=O)\N=c2/sc(cn2C[C@H]2CCCO2)C(C)(C)C)C(F)(F)F)C1
Show InChI InChI=1S/C26H34F3N3O3S/c1-25(2,3)22-15-32(14-19-6-5-11-34-19)24(36-22)30-23(33)20-12-18(26(27,28)29)7-8-21(20)35-16-17-9-10-31(4)13-17/h7-8,12,15,17,19H,5-6,9-11,13-14,16H2,1-4H3/b30-24-/t17-,19-/m1/s1
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141 -39.8n/an/an/an/an/a7.430



AbbVie Inc.

US Patent


Assay Description
HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...


US Patent US8846730 (2014)


BindingDB Entry DOI: 10.7270/Q2028Q6Q
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM133278
PNG
(US8846730, 26)
Show SMILES CN1CCC[C@@H]1COc1ccc(cc1C(=O)\N=c1/sc(cn1C[C@H]1CCCO1)C(C)(C)C)C(F)(F)F
Show InChI InChI=1S/C26H34F3N3O3S/c1-25(2,3)22-15-32(14-19-8-6-12-34-19)24(36-22)30-23(33)20-13-17(26(27,28)29)9-10-21(20)35-16-18-7-5-11-31(18)4/h9-10,13,15,18-19H,5-8,11-12,14,16H2,1-4H3/b30-24-/t18-,19-/m1/s1
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206 -38.8n/an/an/an/an/a7.430



AbbVie Inc.

US Patent


Assay Description
HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...


US Patent US8846730 (2014)


BindingDB Entry DOI: 10.7270/Q2028Q6Q
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM133270
PNG
(US8846730, 12)
Show SMILES CN1CC(COc2ccc(cc2C(=O)\N=c2/sc(cn2C[C@H]2CCCO2)C(C)(C)C)C(F)(F)F)C1
Show InChI InChI=1S/C25H32F3N3O3S/c1-24(2,3)21-14-31(13-18-6-5-9-33-18)23(35-21)29-22(32)19-10-17(25(26,27)28)7-8-20(19)34-15-16-11-30(4)12-16/h7-8,10,14,16,18H,5-6,9,11-13,15H2,1-4H3/b29-23-/t18-/m1/s1
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US Patent
208 -38.8n/an/an/an/an/a7.430



AbbVie Inc.

US Patent


Assay Description
HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...


US Patent US8846730 (2014)


BindingDB Entry DOI: 10.7270/Q2028Q6Q
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM9654
PNG
(US8846730, 20)
Show SMILES CC(C)(C)c1cn(C[C@H]2CCCO2)\c(=N\C(=O)c2cc(ccc2OCc2cccc[n+]2[O-])C(F)(F)F)s1
Show InChI InChI=1S/C26H28F3N3O4S/c1-25(2,3)22-15-31(14-19-8-6-12-35-19)24(37-22)30-23(33)20-13-17(26(27,28)29)9-10-21(20)36-16-18-7-4-5-11-32(18)34/h4-5,7,9-11,13,15,19H,6,8,12,14,16H2,1-3H3/b30-24-/t19-/m1/s1
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209 -38.8n/an/an/an/an/a7.430



AbbVie Inc.

US Patent


Assay Description
HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...


US Patent US8846730 (2014)


BindingDB Entry DOI: 10.7270/Q2028Q6Q
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM133299
PNG
(US8846730, 57)
Show SMILES CN1CCC[C@H]1COc1ccc(cc1C(=O)\N=c1/scc(n1C[C@H]1CCCO1)C(C)(C)C)C(F)(F)F
Show InChI InChI=1S/C26H34F3N3O3S/c1-25(2,3)22-16-36-24(32(22)14-19-8-6-12-34-19)30-23(33)20-13-17(26(27,28)29)9-10-21(20)35-15-18-7-5-11-31(18)4/h9-10,13,16,18-19H,5-8,11-12,14-15H2,1-4H3/b30-24-/t18-,19+/m0/s1
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289 -37.9n/an/an/an/an/a7.430



AbbVie Inc.

US Patent


Assay Description
HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...


US Patent US8846730 (2014)


BindingDB Entry DOI: 10.7270/Q2028Q6Q
More data for this
Ligand-Target Pair
Cannabinoid receptor 2


(Homo sapiens (Human))
BDBM133271
PNG
(US8846730, 15)
Show SMILES CN1CCC(COc2ccc(cc2C(=O)\N=c2/sc(cn2C[C@H]2CCCO2)C(C)(C)C)C(F)(F)F)CC1
Show InChI InChI=1S/C27H36F3N3O3S/c1-26(2,3)23-16-33(15-20-6-5-13-35-20)25(37-23)31-24(34)21-14-19(27(28,29)30)7-8-22(21)36-17-18-9-11-32(4)12-10-18/h7-8,14,16,18,20H,5-6,9-13,15,17H2,1-4H3/b31-25-/t20-/m1/s1
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US Patent
1.00E+3 -34.8n/an/an/an/an/a7.430



AbbVie Inc.

US Patent


Assay Description
HEK293 cells stably expressing human CB2 receptors were grown until a confluent monolayer was formed. Briefly, the cells were harvested and homogeniz...


US Patent US8846730 (2014)


BindingDB Entry DOI: 10.7270/Q2028Q6Q
More data for this
Ligand-Target Pair
* indicates data uncertainty>20%