| Reaction Details |
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 | Report a problem with these data |
| Target | Serine protease 1 |
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| Ligand | BDBM50103651 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_212731 |
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| Ki | 4.7±n/a nM |
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| Citation |  Young, WB; Kolesnikov, A; Rai, R; Sprengeler, PA; Leahy, EM; Shrader, WD; Sangalang, J; Burgess-Henry, J; Spencer, J; Elrod, K; Cregar, L Optimization of a screening lead for factor VIIa/TF. Bioorg Med Chem Lett11:2253-6 (2001) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Serine protease 1 |
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| Name: | Serine protease 1 |
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| Synonyms: | Alpha-trypsin chain 1 | Alpha-trypsin chain 2 | Beta-trypsin | Cationic trypsinogen | PRSS1 | Serine protease 1 | TRP1 | TRY1 | TRY1_HUMAN | TRYP1 | Thrombin & trypsin | Trypsin | Trypsin I | Trypsin-1 |
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| Type: | Enzyme |
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| Mol. Mass.: | 26557.80 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P07477 |
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| Residue: | 247 |
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| Sequence: | MNPLLILTFVAAALAAPFDDDDKIVGGYNCEENSVPYQVSLNSGYHFCGGSLINEQWVVS
AGHCYKSRIQVRLGEHNIEVLEGNEQFINAAKIIRHPQYDRKTLNNDIMLIKLSSRAVIN
ARVSTISLPTAPPATGTKCLISGWGNTASSGADYPDELQCLDAPVLSQAKCEASYPGKIT
SNMFCVGFLEGGKDSCQGDSGGPVVCNGQLQGVVSWGDGCAQKNKPGVYTKVYNYVKWIK
NTIAANS
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| BDBM50103651 |
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| n/a |
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| Name | BDBM50103651 |
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| Synonyms: | 2-(3'-Amino-5-chloro-2-hydroxy-biphenyl-3-yl)-1H-benzoimidazole-5-carboxamidine | CHEMBL73737 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H16ClN5O |
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| Mol. Mass. | 377.827 |
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| SMILES | NC(=N)c1ccc2nc([nH]c2c1)-c1cc(Cl)cc(-c2cccc(N)c2)c1O |
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| Structure | 
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