The following articles (labelled with PubMed ID or TBD) are for your review
PMID | Data | Article Title | Organization |
27570243 |
7 |
Bioactive diterpenoids from Trigonostemon chinensis: Structures, NO inhibitory activities, and interactions with iNOS. |
Nankai University |
27050842 |
39 |
Potent and Selective Human Neuronal Nitric Oxide Synthase Inhibition by Optimization of the 2-Aminopyridine-Based Scaffold with a Pyridine Linker. |
Northwestern University |
25975638 |
23 |
Design, synthesis and biological evaluation of bivalent benzoxazolone and benzothiazolone ligands as potential anti-inflammatory/analgesic agents. |
Beni-Suef University |
25965897 |
15 |
New Monocyclic, Bicyclic, and Tricyclic Ethynylcyanodienones as Activators of the Keap1/Nrf2/ARE Pathway and Inhibitors of Inducible Nitric Oxide Synthase. |
Stony Brook University |
26101565 |
14 |
Selective Acetamidine-Based Nitric Oxide Synthase Inhibitors: Synthesis, Docking, and Biological Studies. |
University of Chieti&Quot;G. D'Annunzio&Quot |
26120733 |
36 |
2-Aminopyridines with a Truncated Side Chain To Improve Human Neuronal Nitric Oxide Synthase Inhibitory Potency and Selectivity. |
Northwestern University |
25881822 |
4 |
Synthesis and biological evaluation of novel pyrazoline derivatives as potent anti-inflammatory agents. |
Sichuan University |
25555141 |
4 |
Structural exploration, synthesis and pharmacological evaluation of novel 5-benzylidenethiazolidine-2,4-dione derivatives as iNOS inhibitors against inflammatory diseases. |
Sichuan University |
25489882 |
63 |
Novel 2,4-disubstituted pyrimidines as potent, selective, and cell-permeable inhibitors of neuronal nitric oxide synthase. |
Northwestern University |
25522110 |
21 |
Structure-based design of bacterial nitric oxide synthase inhibitors. |
University of California |
25149509 |
30 |
Combination of chiral linkers with thiophenecarboximidamide heads to improve the selectivity of inhibitors of neuronal nitric oxide synthase. |
Northwestern University |
24758147 |
31 |
Nitric oxide synthase inhibitors that interact with both heme propionate and tetrahydrobiopterin show high isoform selectivity. |
Northwestern University |
24472039 |
39 |
Simplified 2-aminoquinoline-based scaffold for potent and selective neuronal nitric oxide synthase inhibition. |
Northwestern University |
24447275 |
33 |
Potent and selective double-headed thiophene-2-carboximidamide inhibitors of neuronal nitric oxide synthase for the treatment of melanoma. |
Northwestern University |
24471493 |
1 |
Octulosonic acid derivatives from Roman chamomile (Chamaemelum nobile) with activities against inflammation and metabolic disorder. |
University of Mississippi |
24660051 |
24 |
An Accessible Chiral Linker to Enhance Potency and Selectivity of Neuronal Nitric Oxide Synthase Inhibitors. |
Northwestern University |
23994869 |
6 |
Chemopreventive and antioxidant activity of 6-substituted imidazo[2,1-b]thiazoles. |
Universit£ |
23993333 |
27 |
Chiral linkers to improve selectivity of double-headed neuronal nitric oxide synthase inhibitors. |
Northwestern University |
23867386 |
31 |
In search of potent and selective inhibitors of neuronal nitric oxide synthase with more simple structures. |
Northwestern University |
23547843 |
3 |
Cytotoxicity and modulation of cancer-related signaling by (Z)- and (E)-3,4,3',5'-tetramethoxystilbene isolated from Eugenia rigida. |
The University of Mississippi |
23352768 |
21 |
Cyclopropyl- and methyl-containing inhibitors of neuronal nitric oxide synthase. |
University of California |
23517145 |
11 |
Anti-inflammatory lanostanoids and lactone derivatives from Antrodia camphorata. |
National Sun Yat-Sen University |
23451760 |
18 |
Structure-guided design of selective inhibitors of neuronal nitric oxide synthase. |
Northwestern University |
23142320 |
14 |
Optimization of thiazole analogues of resveratrol for induction of NAD(P)H:quinone reductase 1 (QR1). |
Purdue University |
22703704 |
3 |
New synthesis and promising neuroprotective role in experimental ischemic stroke of ONO-1714. |
Instituto Cajal (Csic) |
22633833 |
5 |
Rational design, synthesis, and pharmacological properties of pyranochalcone derivatives as potent anti-inflammatory agents. |
Sichuan University |
22366656 |
5 |
Oroxylin A analogs exhibited strong inhibitory activities against iNOS-mediated nitric oxide (NO) production. |
Kangwon National University |
21115251 |
20 |
Biologically active constituents from the fruiting body of Taiwanofungus camphoratus. |
National Formosa University |
19144449 |
22 |
Synthesis and evaluation of pyrido[1,2-a]pyrimidines as inhibitors of nitric oxide synthases. |
Christian-Albrechts-University of Kiel |
18926710 |
18 |
New diterpenoids and the bioactivity of Erythrophleum fordii. |
National Cheng Kung University |
18485715 |
29 |
Design and synthesis of 7-alkoxy-4-heteroarylamino-3-quinolinecarbonitriles as dual inhibitors of c-Src kinase and nitric oxide synthase. |
China Pharmaceutical University |
17937988 |
26 |
Design, synthesis, and preliminary evaluation of 4-(6-(3-nitroguanidino)hexanamido)pyrrolidine derivatives as potential iNOS inhibitors. |
Shandong University |
14736250 |
50 |
Potent and selective conformationally restricted neuronal nitric oxide synthase inhibitors. |
Northwestern University |
12699384 |
69 |
Aromatic reduced amide bond peptidomimetics as selective inhibitors of neuronal nitric oxide synthase. |
Northwestern University |
14667223 |
72 |
Computer modeling of selective regions in the active site of nitric oxide synthases: implication for the design of isoform-selective inhibitors. |
Northwestern University |
11472219 |
27 |
Reduced amide bond peptidomimetics. (4S)-N-(4-amino-5-[aminoakyl]aminopentyl)-N'-nitroguanidines, potent and highly selective inhibitors of neuronal nitric oxide synthase. |
Northwestern University |
10956202 |
51 |
Synthesis and evaluation of peptidomimetics as selective inhibitors and active site probes of nitric oxide synthases. |
Northwestern University |
10447959 |
30 |
N(omega)-Nitroarginine-containing dipeptide amides. Potent and highly selective inhibitors of neuronal nitric oxide synthase. |
Northwestern University |
9554868 |
40 |
2-Iminohomopiperidinium salts as selective inhibitors of inducible nitric oxide synthase (iNOS). |
Pfizer |
9397167 |
15 |
Potent and selective inhibition of neuronal nitric oxide synthase by N omega-propyl-L-arginine. |
Northwestern University |
9288162 |
40 |
Selective inhibition of neuronal nitric oxide synthase by N omega-nitroarginine-and phenylalanine-containing dipeptides and dipeptide esters. |
Northwestern University |
7525961 |
12 |
L-N6-(1-iminoethyl)lysine: a selective inhibitor of inducible nitric oxide synthase. |
G. D. Searle Research and Development |
7518001 |
5 |
Approaches toward selective inhibition of nitric oxide synthase. |
University of Michigan |
11133088 |
46 |
1H-pyrazole-1-carboxamidines: new inhibitors of nitric oxide synthase. |
Northwestern University |
22386564 |
43 |
Optimization of the aromatase inhibitory activities of pyridylthiazole analogues of resveratrol. |
Purdue University |
22370337 |
30 |
Intramolecular hydrogen bonding: a potential strategy for more bioavailable inhibitors of neuronal nitric oxide synthase. |
Northwestern University |
22182498 |
71 |
Heteroaromatic-aminomethyl quinolones: potent and selective iNOS inhibitors. |
Afraxis |
22148193 |
6 |
Secondary metabolites from the roots of Neolitsea daibuensis and their anti-inflammatory activity. |
Kaohsiung Medical University |
22115618 |
13 |
Bis-chalcone analogues as potent NO production inhibitors and as cytotoxic agents. |
National Cheng Kung University |
21978950 |
28 |
Design, synthesis, and biological evaluation of callophycin A and analogues as potential chemopreventive and anticancer agents. |
University of Hawaii At Hilo |
21846089 |
12 |
Anti-inflammatory endiandric acid analogues from the roots of Beilschmiedia tsangii. |
Kaohsiung Medical University |
21809851 |
21 |
Improved synthesis of chiral pyrrolidine inhibitors and their binding properties to neuronal nitric oxide synthase. |
Northwestern University |
21782456 |
7 |
Oxadiazole derivatives containing 1,4-benzodioxan as potential immunosuppressive agents against RAW264.7 cells. |
Nanjing University |
20931971 |
155 |
Discovery of dual inducible/neuronal nitric oxide synthase (iNOS/nNOS) inhibitor development candidate 4-((2-cyclobutyl-1H-imidazo[4,5-b]pyrazin-1-yl)methyl)-7,8-difluoroquinolin-2(1H)-one (KD7332) part 2: identification of a novel, potent, and selective series of benzimidazole-quinolinone iNOS/nNO |
Kalypsys |
21410186 |
43 |
Symmetric double-headed aminopyridines, a novel strategy for potent and membrane-permeable inhibitors of neuronal nitric oxide synthase. |
Northwestern University |
21381754 |
15 |
Synthesis and biological evaluation of novel 5-benzylidenethiazolidine-2,4-dione derivatives for the treatment of inflammatory diseases. |
Sichuan University |
20958055 |
133 |
Exploration of the active site of neuronal nitric oxide synthase by the design and synthesis of pyrrolidinomethyl 2-aminopyridine derivatives. |
Northwestern University |
20933416 |
33 |
N-Substituted acetamidines and 2-methylimidazole derivatives as selective inhibitors of neuronal nitric oxide synthase. |
Università |
20833542 |
16 |
Peripheral but crucial: a hydrophobic pocket (Tyr(706), Leu(337), and Met(336)) for potent and selective inhibition of neuronal nitric oxide synthase. |
Northwestern University |
20673724 |
33 |
Structure-based design, synthesis, and biological evaluation of lipophilic-tailed monocationic inhibitors of neuronal nitric oxide synthase. |
Northwestern University |
20527891 |
7 |
Selective synthesis and biological evaluation of sulfate-conjugated resveratrol metabolites. |
Purdue University |
20441173 |
19 |
2-aminoimidazole amino acids as inhibitors of the binuclear manganese metalloenzyme human arginase I. |
University of Pennsylvania |
19963381 |
18 |
Potent and selective neuronal nitric oxide synthase inhibitors with improved cellular permeability. |
Northwestern University |
| 16 |
Synthesis of phosphorus-containing amino acid analogs as inhibitors of nitric oxide synthase |
TBA |
| 3 |
Fungal metabolite of naftazone inhibits nitrite production by activated murine macrophages |
TBA |
| 10 |
1,2-diaminobenzimidazoles : Selective inhibitors of nitric oxide synthase derived from aminoguanidine |
TBA |
19268602 |
18 |
Analogues of 2-aminopyridine-based selective inhibitors of neuronal nitric oxide synthase with increased bioavailability. |
Northwestern University |
19125620 |
96 |
Discovery of highly potent and selective inhibitors of neuronal nitric oxide synthase by fragment hopping. |
Northwestern University |
19041241 |
21 |
Synthesis of biflavones having a 6-O-7'' linkage and effects on cyclooxygenase-2 and inducible nitric oxide synthase. |
Kangwon National University |
18930653 |
28 |
The design, synthesis and biological evaluation of 7-alkoxy-4-heteroarylamino-3-cyanoquinolines as dual inhibitors of c-Src and iNOS. |
China Pharmaceutical University |
18502134 |
55 |
Inhibitory effects of a series of 7-substituted-indazoles toward nitric oxide synthases: particular potency of 1H-indazole-7-carbonitrile. |
Université |
15270564 |
1 |
New crinine-type alkaloids with inhibitory effect on induction of inducible nitric oxide synthase from Crinum yemense. |
Mansoura University |
17239601 |
33 |
Selective L-nitroargininylaminopyrrolidine and L-nitroargininylaminopiperidine neuronal nitric oxide synthase inhibitors. |
Northwestern University |
17034131 |
19 |
Conformationally restricted dipeptide amides as potent and selective neuronal nitric oxide synthase inhibitors. |
Northwestern University |
14698148 |
44 |
4,5-Disubstituted-1,3-oxazolidin-2-imine derivatives: a new class of orally bioavailable nitric oxide synthase inhibitor. |
Dainippon Pharmaceutical |
12161118 |
28 |
Design and synthesis of orally bioavailable inhibitors of inducible nitric oxide synthase. Part 1: synthesis and biological evaluation of dihydropyridin-2-imines. |
Fukui Research Institute |
12113816 |
7 |
The synthesis and effect of fluorinated chalcone derivatives on nitric oxide production. |
Universidad De Valencia |
11133090 |
2 |
Evaluation of new L-thiocitrulline derivatives as inhibitors of nitric oxide synthase. |
Wake Forest University |
10843221 |
4 |
Examination of N-hydroxylation as a prerequisite mechanism of nitric oxide synthase inactivation. |
University At Buffalo |
10571154 |
8 |
Guanidine-substituted imidazoles as inhibitors of nitric oxide synthase. |
Wake Forest University Winston-Salem |
30802056 |
63 |
Optimization of Blood-Brain Barrier Permeability with Potent and Selective Human Neuronal Nitric Oxide Synthase Inhibitors Having a 2-Aminopyridine Scaffold. |
Northwestern University |
10346937 |
15 |
Synthesis and evaluation of new sulfur-containing L-arginine-derived inhibitors of nitric oxide synthase. |
Wake Forest University |
9873655 |
10 |
Conformationally constrained NO synthase inhibitors: rigid analogs of L-N-iminoethylornithine. |
Université |
30925056 |
9 |
Novel Pyrazolo[4,3- d]pyrimidine as Potent and Orally Active Inducible Nitric Oxide Synthase (iNOS) Dimerization Inhibitor with Efficacy in Rheumatoid Arthritis Mouse Model. |
Anhui Medical University |
32302123 |
114 |
First Contact: 7-Phenyl-2-Aminoquinolines, Potent and Selective Neuronal Nitric Oxide Synthase Inhibitors That Target an Isoform-Specific Aspartate. |
Northwestern University |
9651169 |
49 |
Nitroaromatic amino acids as inhibitors of neuronal nitric oxide synthase. |
Abbott Laboratories |
8978842 |
9 |
Synthesis and evaluation of two positron-labeled nitric oxide synthase inhibitors, S-[11C]methylisothiourea and S-(2-[18F]fluoroethyl)isothiourea, as potential positron emission tomography tracers. |
Washington University |
26469213 |
58 |
Phenyl Ether- and Aniline-Containing 2-Aminoquinolines as Potent and Selective Inhibitors of Neuronal Nitric Oxide Synthase. |
Northwestern University |
25058929 |
58 |
Discovery and optimization of 1,3,5-trisubstituted pyrazolines as potent and highly selective allosteric inhibitors of protein kinase C-?. |
Saarland University |
14738400 |
1 |
Plakolide A, a new gamma-lactone from the marine sponge Plakortis sp. |
Harbor Branch Oceanographic Institution |
29689474 |
32 |
Discovery of N-{3-[(ethanimidoylamino)methyl]benzyl}-l-prolinamide dihydrochloride: A new potent and selective inhibitor of the inducible nitric oxide synthase as a promising agent for the therapy of malignant glioma. |
University of Chieti "G. D'Annunzio |
28422508 |
78 |
Nitrile in the Hole: Discovery of a Small Auxiliary Pocket in Neuronal Nitric Oxide Synthase Leading to the Development of Potent and Selective 2-Aminoquinoline Inhibitors. |
Northwestern University |
28776992 |
110 |
Hydrophilic, Potent, and Selective 7-Substituted 2-Aminoquinolines as Improved Human Neuronal Nitric Oxide Synthase Inhibitors. |
Northwestern University |
29091437 |
50 |
Improvement of Cell Permeability of Human Neuronal Nitric Oxide Synthase Inhibitors Using Potent and Selective 2-Aminopyridine-Based Scaffolds with a Fluorobenzene Linker. |
Northwestern University |
17524982 |
10 |
Alkyl-CoA disulfides as inhibitors and mechanistic probes for FabH enzymes. |
Portland State University |
17379147 |
5 |
Covalent reactions of wortmannin under physiological conditions. |
Massachusetts General Hospital |