105 articles for thisTarget

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The following articles (labelled with PubMed ID or TBD) are for your review

PMID	Data	Article Title	Organization
27570243	7	Bioactive diterpenoids from Trigonostemon chinensis: Structures, NO inhibitory activities, and interactions with iNOS.	Nankai University
27050842	39	Potent and Selective Human Neuronal Nitric Oxide Synthase Inhibition by Optimization of the 2-Aminopyridine-Based Scaffold with a Pyridine Linker.	Northwestern University
25975638	23	Design, synthesis and biological evaluation of bivalent benzoxazolone and benzothiazolone ligands as potential anti-inflammatory/analgesic agents.	Beni-Suef University
25965897	15	New Monocyclic, Bicyclic, and Tricyclic Ethynylcyanodienones as Activators of the Keap1/Nrf2/ARE Pathway and Inhibitors of Inducible Nitric Oxide Synthase.	Stony Brook University
26101565	14	Selective Acetamidine-Based Nitric Oxide Synthase Inhibitors: Synthesis, Docking, and Biological Studies.	University of Chieti&Quot;G. D'Annunzio&Quot
26120733	36	2-Aminopyridines with a Truncated Side Chain To Improve Human Neuronal Nitric Oxide Synthase Inhibitory Potency and Selectivity.	Northwestern University
25881822	4	Synthesis and biological evaluation of novel pyrazoline derivatives as potent anti-inflammatory agents.	Sichuan University
25555141	4	Structural exploration, synthesis and pharmacological evaluation of novel 5-benzylidenethiazolidine-2,4-dione derivatives as iNOS inhibitors against inflammatory diseases.	Sichuan University
25489882	63	Novel 2,4-disubstituted pyrimidines as potent, selective, and cell-permeable inhibitors of neuronal nitric oxide synthase.	Northwestern University
25522110	21	Structure-based design of bacterial nitric oxide synthase inhibitors.	University of California
25149509	30	Combination of chiral linkers with thiophenecarboximidamide heads to improve the selectivity of inhibitors of neuronal nitric oxide synthase.	Northwestern University
24758147	31	Nitric oxide synthase inhibitors that interact with both heme propionate and tetrahydrobiopterin show high isoform selectivity.	Northwestern University
24472039	39	Simplified 2-aminoquinoline-based scaffold for potent and selective neuronal nitric oxide synthase inhibition.	Northwestern University
24447275	33	Potent and selective double-headed thiophene-2-carboximidamide inhibitors of neuronal nitric oxide synthase for the treatment of melanoma.	Northwestern University
24471493	1	Octulosonic acid derivatives from Roman chamomile (Chamaemelum nobile) with activities against inflammation and metabolic disorder.	University of Mississippi
24660051	24	An Accessible Chiral Linker to Enhance Potency and Selectivity of Neuronal Nitric Oxide Synthase Inhibitors.	Northwestern University
23994869	6	Chemopreventive and antioxidant activity of 6-substituted imidazo[2,1-b]thiazoles.	Universit£
23993333	27	Chiral linkers to improve selectivity of double-headed neuronal nitric oxide synthase inhibitors.	Northwestern University
23867386	31	In search of potent and selective inhibitors of neuronal nitric oxide synthase with more simple structures.	Northwestern University
23547843	3	Cytotoxicity and modulation of cancer-related signaling by (Z)- and (E)-3,4,3',5'-tetramethoxystilbene isolated from Eugenia rigida.	The University of Mississippi
23352768	21	Cyclopropyl- and methyl-containing inhibitors of neuronal nitric oxide synthase.	University of California
23517145	11	Anti-inflammatory lanostanoids and lactone derivatives from Antrodia camphorata.	National Sun Yat-Sen University
23451760	18	Structure-guided design of selective inhibitors of neuronal nitric oxide synthase.	Northwestern University
23142320	14	Optimization of thiazole analogues of resveratrol for induction of NAD(P)H:quinone reductase 1 (QR1).	Purdue University
22703704	3	New synthesis and promising neuroprotective role in experimental ischemic stroke of ONO-1714.	Instituto Cajal (Csic)
22633833	5	Rational design, synthesis, and pharmacological properties of pyranochalcone derivatives as potent anti-inflammatory agents.	Sichuan University
22366656	5	Oroxylin A analogs exhibited strong inhibitory activities against iNOS-mediated nitric oxide (NO) production.	Kangwon National University
21115251	20	Biologically active constituents from the fruiting body of Taiwanofungus camphoratus.	National Formosa University
19144449	22	Synthesis and evaluation of pyrido[1,2-a]pyrimidines as inhibitors of nitric oxide synthases.	Christian-Albrechts-University of Kiel
18926710	18	New diterpenoids and the bioactivity of Erythrophleum fordii.	National Cheng Kung University
18485715	29	Design and synthesis of 7-alkoxy-4-heteroarylamino-3-quinolinecarbonitriles as dual inhibitors of c-Src kinase and nitric oxide synthase.	China Pharmaceutical University
17937988	26	Design, synthesis, and preliminary evaluation of 4-(6-(3-nitroguanidino)hexanamido)pyrrolidine derivatives as potential iNOS inhibitors.	Shandong University
14736250	50	Potent and selective conformationally restricted neuronal nitric oxide synthase inhibitors.	Northwestern University
12699384	69	Aromatic reduced amide bond peptidomimetics as selective inhibitors of neuronal nitric oxide synthase.	Northwestern University
11472219	27	Reduced amide bond peptidomimetics. (4S)-N-(4-amino-5-[aminoakyl]aminopentyl)-N'-nitroguanidines, potent and highly selective inhibitors of neuronal nitric oxide synthase.	Northwestern University
10956202	51	Synthesis and evaluation of peptidomimetics as selective inhibitors and active site probes of nitric oxide synthases.	Northwestern University
10447959	30	N(omega)-Nitroarginine-containing dipeptide amides. Potent and highly selective inhibitors of neuronal nitric oxide synthase.	Northwestern University
9554868	40	2-Iminohomopiperidinium salts as selective inhibitors of inducible nitric oxide synthase (iNOS).	Pfizer
9397167	15	Potent and selective inhibition of neuronal nitric oxide synthase by N omega-propyl-L-arginine.	Northwestern University
9288162	40	Selective inhibition of neuronal nitric oxide synthase by N omega-nitroarginine-and phenylalanine-containing dipeptides and dipeptide esters.	Northwestern University
7525961	12	L-N6-(1-iminoethyl)lysine: a selective inhibitor of inducible nitric oxide synthase.	G. D. Searle Research and Development
7518001	5	Approaches toward selective inhibition of nitric oxide synthase.	University of Michigan
11133088	46	1H-pyrazole-1-carboxamidines: new inhibitors of nitric oxide synthase.	Northwestern University
22386564	43	Optimization of the aromatase inhibitory activities of pyridylthiazole analogues of resveratrol.	Purdue University
22370337	30	Intramolecular hydrogen bonding: a potential strategy for more bioavailable inhibitors of neuronal nitric oxide synthase.	Northwestern University
22182498	71	Heteroaromatic-aminomethyl quinolones: potent and selective iNOS inhibitors.	Afraxis
22148193	6	Secondary metabolites from the roots of Neolitsea daibuensis and their anti-inflammatory activity.	Kaohsiung Medical University
22115618	13	Bis-chalcone analogues as potent NO production inhibitors and as cytotoxic agents.	National Cheng Kung University
21978950	28	Design, synthesis, and biological evaluation of callophycin A and analogues as potential chemopreventive and anticancer agents.	University of Hawaii At Hilo
21846089	12	Anti-inflammatory endiandric acid analogues from the roots of Beilschmiedia tsangii.	Kaohsiung Medical University
21809851	21	Improved synthesis of chiral pyrrolidine inhibitors and their binding properties to neuronal nitric oxide synthase.	Northwestern University
21782456	7	Oxadiazole derivatives containing 1,4-benzodioxan as potential immunosuppressive agents against RAW264.7 cells.	Nanjing University
20931971	155	Discovery of dual inducible/neuronal nitric oxide synthase (iNOS/nNOS) inhibitor development candidate 4-((2-cyclobutyl-1H-imidazo[4,5-b]pyrazin-1-yl)methyl)-7,8-difluoroquinolin-2(1H)-one (KD7332) part 2: identification of a novel, potent, and selective series of benzimidazole-quinolinone iNOS/nNO	Kalypsys
21410186	43	Symmetric double-headed aminopyridines, a novel strategy for potent and membrane-permeable inhibitors of neuronal nitric oxide synthase.	Northwestern University
21381754	15	Synthesis and biological evaluation of novel 5-benzylidenethiazolidine-2,4-dione derivatives for the treatment of inflammatory diseases.	Sichuan University
20958055	133	Exploration of the active site of neuronal nitric oxide synthase by the design and synthesis of pyrrolidinomethyl 2-aminopyridine derivatives.	Northwestern University
20933416	33	N-Substituted acetamidines and 2-methylimidazole derivatives as selective inhibitors of neuronal nitric oxide synthase.	Università
20833542	16	Peripheral but crucial: a hydrophobic pocket (Tyr(706), Leu(337), and Met(336)) for potent and selective inhibition of neuronal nitric oxide synthase.	Northwestern University
20673724	33	Structure-based design, synthesis, and biological evaluation of lipophilic-tailed monocationic inhibitors of neuronal nitric oxide synthase.	Northwestern University
20527891	7	Selective synthesis and biological evaluation of sulfate-conjugated resveratrol metabolites.	Purdue University
20441173	19	2-aminoimidazole amino acids as inhibitors of the binuclear manganese metalloenzyme human arginase I.	University of Pennsylvania
19963381	18	Potent and selective neuronal nitric oxide synthase inhibitors with improved cellular permeability.	Northwestern University
	16	Synthesis of phosphorus-containing amino acid analogs as inhibitors of nitric oxide synthase	TBA
	3	Fungal metabolite of naftazone inhibits nitrite production by activated murine macrophages	TBA
	10	1,2-diaminobenzimidazoles : Selective inhibitors of nitric oxide synthase derived from aminoguanidine	TBA
19268602	18	Analogues of 2-aminopyridine-based selective inhibitors of neuronal nitric oxide synthase with increased bioavailability.	Northwestern University
19125620	96	Discovery of highly potent and selective inhibitors of neuronal nitric oxide synthase by fragment hopping.	Northwestern University
19041241	21	Synthesis of biflavones having a 6-O-7'' linkage and effects on cyclooxygenase-2 and inducible nitric oxide synthase.	Kangwon National University
18930653	28	The design, synthesis and biological evaluation of 7-alkoxy-4-heteroarylamino-3-cyanoquinolines as dual inhibitors of c-Src and iNOS.	China Pharmaceutical University
18502134	55	Inhibitory effects of a series of 7-substituted-indazoles toward nitric oxide synthases: particular potency of 1H-indazole-7-carbonitrile.	Université
15270564	1	New crinine-type alkaloids with inhibitory effect on induction of inducible nitric oxide synthase from Crinum yemense.	Mansoura University
17239601	33	Selective L-nitroargininylaminopyrrolidine and L-nitroargininylaminopiperidine neuronal nitric oxide synthase inhibitors.	Northwestern University
17034131	19	Conformationally restricted dipeptide amides as potent and selective neuronal nitric oxide synthase inhibitors.	Northwestern University
14698148	44	4,5-Disubstituted-1,3-oxazolidin-2-imine derivatives: a new class of orally bioavailable nitric oxide synthase inhibitor.	Dainippon Pharmaceutical
12161118	28	Design and synthesis of orally bioavailable inhibitors of inducible nitric oxide synthase. Part 1: synthesis and biological evaluation of dihydropyridin-2-imines.	Fukui Research Institute
12113816	7	The synthesis and effect of fluorinated chalcone derivatives on nitric oxide production.	Universidad De Valencia
11133090	2	Evaluation of new L-thiocitrulline derivatives as inhibitors of nitric oxide synthase.	Wake Forest University
10843221	4	Examination of N-hydroxylation as a prerequisite mechanism of nitric oxide synthase inactivation.	University At Buffalo
10571154	8	Guanidine-substituted imidazoles as inhibitors of nitric oxide synthase.	Wake Forest University Winston-Salem
30802056	63	Optimization of Blood-Brain Barrier Permeability with Potent and Selective Human Neuronal Nitric Oxide Synthase Inhibitors Having a 2-Aminopyridine Scaffold.	Northwestern University
10346937	15	Synthesis and evaluation of new sulfur-containing L-arginine-derived inhibitors of nitric oxide synthase.	Wake Forest University
9873655	10	Conformationally constrained NO synthase inhibitors: rigid analogs of L-N-iminoethylornithine.	Université
30925056	9	Novel Pyrazolo[4,3- d]pyrimidine as Potent and Orally Active Inducible Nitric Oxide Synthase (iNOS) Dimerization Inhibitor with Efficacy in Rheumatoid Arthritis Mouse Model.	Anhui Medical University
32302123	114	First Contact: 7-Phenyl-2-Aminoquinolines, Potent and Selective Neuronal Nitric Oxide Synthase Inhibitors That Target an Isoform-Specific Aspartate.	Northwestern University
9651169	49	Nitroaromatic amino acids as inhibitors of neuronal nitric oxide synthase.	Abbott Laboratories
8978842	9	Synthesis and evaluation of two positron-labeled nitric oxide synthase inhibitors, S-[11C]methylisothiourea and S-(2-[18F]fluoroethyl)isothiourea, as potential positron emission tomography tracers.	Washington University
26469213	58	Phenyl Ether- and Aniline-Containing 2-Aminoquinolines as Potent and Selective Inhibitors of Neuronal Nitric Oxide Synthase.	Northwestern University
25058929	58	Discovery and optimization of 1,3,5-trisubstituted pyrazolines as potent and highly selective allosteric inhibitors of protein kinase C-?.	Saarland University
14738400	1	Plakolide A, a new gamma-lactone from the marine sponge Plakortis sp.	Harbor Branch Oceanographic Institution
29689474	32	Discovery of N-{3-[(ethanimidoylamino)methyl]benzyl}-l-prolinamide dihydrochloride: A new potent and selective inhibitor of the inducible nitric oxide synthase as a promising agent for the therapy of malignant glioma.	University of Chieti "G. D'Annunzio
28422508	78	Nitrile in the Hole: Discovery of a Small Auxiliary Pocket in Neuronal Nitric Oxide Synthase Leading to the Development of Potent and Selective 2-Aminoquinoline Inhibitors.	Northwestern University
28776992	110	Hydrophilic, Potent, and Selective 7-Substituted 2-Aminoquinolines as Improved Human Neuronal Nitric Oxide Synthase Inhibitors.	Northwestern University
29091437	50	Improvement of Cell Permeability of Human Neuronal Nitric Oxide Synthase Inhibitors Using Potent and Selective 2-Aminopyridine-Based Scaffolds with a Fluorobenzene Linker.	Northwestern University
17524982	10	Alkyl-CoA disulfides as inhibitors and mechanistic probes for FabH enzymes.	Portland State University
17379147	5	Covalent reactions of wortmannin under physiological conditions.	Massachusetts General Hospital