The following articles (labelled with PubMed ID or TBD) are for your review
PMID | Data | Article Title | Organization |
26970660 |
3 |
Development of a potent 2-oxoamide inhibitor of secreted phospholipase A2 guided by molecular docking calculations and molecular dynamics simulations. |
National and Kapodistrian University of Athens |
23164706 |
7 |
Identification of inhibitors against interaction between pro-inflammatory sPLA2-IIA protein and integrinavß3. |
University of California |
23220644 |
50 |
Optimization of 5-hydroxytryptamines as dual function inhibitors targeting phospholipase A2 and leukotriene A4 hydrolase. |
Peking University |
9677277 |
22 |
A new cacospongionolide inhibitor of human secretory phospholipase A2 from the Tyrrhenian sponge Fasciospongia cavernosa and absolute configuration of cacospongionolides. |
Istituto Per La Chimica Di Molecole Di Interesse Biologico Cnr |
9703468 |
6 |
Synthesis and comparison of the antiinflammatory activity of manoalide and cacospongionolide B analogues. |
Universit£ |
8978846 |
68 |
Synthesis and phospholipase A2 inhibitory activity of thielocin B3 derivatives. |
Shionogi |
21555224 |
16 |
Quinoline-4-methyl esters as human nonpancreatic secretory phospholipase A2 inhibitors. |
Peking University |
21216150 |
16 |
Inhibition of secreted phospholipases A2 by 2-oxoamides based ona-amino acids: Synthesis, in vitro evaluation and molecular docking calculations. |
University of Athens |
20417107 |
64 |
Design of new potent and selective secretory phospholipase A(2) inhibitors. 6-Synthesis, structure-activity relationships and molecular modelling of 1-substituted-4-[4,5-dihydro-1,2,4-(4H)-oxadiazol-5-one-3-yl(methyl)]-functionalized aryl piperazin/one/dione derivatives. |
Universit£ |
| 1 |
A simple synthesis of biaryl phospholipase A2 inhibitors: Probing hydrophobic effects |
TBA |
| 3 |
Analogs of the marine natural product scalaradial lacking the α,β-unsaturated aldehyde: effects on human synovial fluid phospholipase A2 and macrophage lipid mediator production |
TBA |
| 24 |
Vinylogous hydroxamic acids: 5-lipoxygenase inhibitors |
TBA |
19090779 |
12 |
Discovery of multitarget inhibitors by combining molecular docking with common pharmacophore matching. |
Peking University |
18818074 |
81 |
Simplified YM-26734 inhibitors of secreted phospholipase A2 group IIA. |
University of Washington |
18605714 |
205 |
Highly specific and broadly potent inhibitors of mammalian secreted phospholipases A2. |
University of Washington |
11374954 |
6 |
New sesquiterpene derivatives from the sponge Dysidea species with a selective inhibitor profile against human phospholipase A2 and other leukocyte functions. |
Università |
17335183 |
78 |
Inhibition of secreted phospholipase A2. 4-glycerol derivatives of 4,5-dihydro-3-(4-tetradecyloxybenzyl)-1,2,4-4H-oxadiazol-5-one with broad activities. |
Université |
16686528 |
40 |
The first potent inhibitor of mammalian group X secreted phospholipase A2: elucidation of sites for enhanced binding. |
University of Washington |
16504502 |
8 |
Synthesis of phospholipase A2 inhibitory biflavonoids. |
Kangwon National University |
15689175 |
25 |
Carbocyclic[g]indole inhibitors of human nonpancreatic s-PLA2. |
Eli Lilly |
11551751 |
18 |
Novel 3-dodecanoylindole-2-carboxylic acid inhibitors of cytosolic phospholipase A(2). |
University of MüNster |
27774123 |
37 |
Discovery of AZD2716: A Novel Secreted Phospholipase A |
Astrazeneca |
10698455 |
13 |
Synthesis and enzyme inhibitory activities of a series of lipidic diamine and aminoalcohol derivatives on cytosolic and secretory phospholipases A2. |
Univ. De Valencia |
30300845 |
43 |
1-(2-Hydroxybenzoyl)-thiosemicarbazides are promising antimicrobial agents targeting d-alanine-d-alanine ligase in bacterio. |
Universit£ |
10021941 |
6 |
Synthesis and PLA2-inhibitory properties of 2(R)-acetamido-alkylphosphomethanols with a variable aggregate anchor. |
Tumor Biology Center |
9934459 |
6 |
Design and synthesis of new secretory phospholipase A2 inhibitor of a phospholipid analog. |
Kwansei Gakuin University |
9005255 |
74 |
Indole inhibitors of human nonpancreatic secretory phospholipase A2. 1. Indole-3-acetamides. |
Eli Lilly |
8978844 |
86 |
Indole inhibitors of human nonpancreatic secretory phospholipase A2. 3. Indole-3-glyoxamides. |
Eli Lilly |
8978843 |
119 |
Indole inhibitors of human nonpancreatic secretory phospholipase A2. 2. Indole-3-acetamides with additional functionality. |
Eli Lilly |
8411020 |
2 |
N-(carboxymethyl)-N-[3,5-bis(decyloxy)-phenyl]glycine (Ro 23-9358): a potent inhibitor of secretory phospholipases A2 with antiinflammatory activity. |
Roche Research Center |
8126692 |
31 |
Discovery of new non-phospholipid inhibitors of the secretory phospholipases A2. |
Fisons |
30034586 |
90 |
Design of Selective sPLA |
Astrazeneca |
30034585 |
49 |
Discovery of a Series of Indole-2 Carboxamides as Selective Secreted Phospholipase A |
Astrazeneca |