44 articles for thisTarget

---

The following articles (labelled with PubMed ID or TBD) are for your review

PMID	Data	Article Title	Organization
10450960	3	Isolation and structure of SCH 351633: a novel hepatitis C virus (HCV) NS3 protease inhibitor from the fungus Penicillium griseofulvum.	Schering-Plough Research Institute
17113777	1	Phenylglycine as a novel P2 scaffold in hepatitis C virus NS3 protease inhibitors.	Uppsala University
16078825	8	Design and synthesis of depeptidized macrocyclic inhibitors of hepatitis C NS3-4A protease using structure-based drug design.	Schering-Plough Research Institute
15633995	66	Control of hepatitis C: a medicinal chemistry perspective.	University Of Wollongong
15546725	3	Antiviral compounds from traditional Chinese medicines Galla Chinese as inhibitors of HCV NS3 protease.	Peking University
15357995	18	SAR and pharmacokinetic studies on phenethylamide inhibitors of the hepatitis C virus NS3/NS4A serine protease.	Merck Research Laboratories
11206459	29	Inhibition of hepatitis C virus NS3 protease activity by product-based peptides is dependent on helicase domain.	Uppsala University
11055336	2	NMR line-broadening and transferred NOESY as a medicinal chemistry tool for studying inhibitors of the hepatitis C virus NS3 protease domain.	Boehringer Ingelheim Pharmaceuticals
11055335	27	Highly potent and selective peptide-based inhibitors of the hepatitis C virus serine protease: towards smaller inhibitors.	Boehringer Ingelheim Pharmaceuticals
9873421	30	Peptide-based inhibitors of the hepatitis C virus serine protease.	Boehringer Ingelheim (Canada)
16730985	13	P2-P4 macrocyclic inhibitors of hepatitis C virus NS3-4A serine protease.	Schering-Plough Research Institute
16722622	24	Discovery of proline sulfonamides as potent and selective hepatitis C virus NS5b polymerase inhibitors. Evidence for a new NS5b polymerase binding site.	Wyeth Research
16274990	21	Design and synthesis of 3,4-dihydro-1H-[1]-benzothieno[2,3-c]pyran and 3,4-dihydro-1H-pyrano[3,4-b]benzofuran derivatives as non-nucleoside inhibitors of HCV NS5B RNA dependent RNA polymerase.	Wyeth Research
16190750	7	Design, synthesis, and biological activity of m-tyrosine-based 16- and 17-membered macrocyclic inhibitors of hepatitis C virus NS3 serine protease.	Schering-Plough Research Institute
16112859	6	Synthesis and biological activity of macrocyclic inhibitors of hepatitis C virus (HCV) NS3 protease.	Schering-Plough Research Institute
15982872	24	Investigation of glycine alpha-ketoamide HCV NS3 protease inhibitors: effect of carboxylic acid isosteres.	Pharmaceutical Research Institute
15588076	6	The design and enzyme-bound crystal structure of indoline based peptidomimetic inhibitors of hepatitis C virus NS3 protease.	Mrl Rome
15341970	59	P4 and P1' optimization of bicycloproline P2 bearing tetrapeptidyl alpha-ketoamides as HCV protease inhibitors.	Eli Lilly
15261297	18	P4 cap modified tetrapeptidyl alpha-ketoamides as potent HCV NS3 protease inhibitors.	Eli Lilly
15115392	52	Non-peptidic small-molecule inhibitors of the single-chain hepatitis C virus NS3 protease/NS4A cofactor complex discovered by structure-based NMR screening.	Schering-Plough Research Institute
15050632	17	Inhibitors of hepatitis C virus NS3.4A protease. Part 3: P2 proline variants.	Vertex Pharmaceuticals
15006379	44	Inhibitors of hepatitis C virus NS3.4A protease 2. Warhead SAR and optimization.	Vertex Pharmaceuticals
14695826	13	NMR structural characterization of peptide inhibitors bound to the Hepatitis C virus NS3 protease: design of a new P2 substituent.	Boehringer Ingelheim (Canada)
14611859	3	Two antiviral compounds from the plant Stylogne cauliflora as inhibitors of HCV NS3 protease.	Schering-Plough Research Institute
14592508	23	Inhibitors of hepatitis C virus NS3.4A protease 1. Non-charged tetrapeptide variants.	Vertex Pharmaceuticals
12873506	8	Novel, potent phenethylamide inhibitors of the hepatitis C virus (HCV) NS3 protease: probing the role of P2 aryloxyprolines with hybrid structures.	Mrl Rome
12643933	27	Design and synthesis of potent, non-peptide inhibitors of HCV NS3 protease.	Bristol-Myers Squibb
12617891	37	Design and synthesis of bicyclic pyrimidinone-based HCV NS3 protease inhibitors.	Bristol-Myers Squibb Pharmaceutical Research Institute
12540231	39	Phenethyl amides as novel noncovalent inhibitors of hepatitis C virus NS3/4A protease: discovery, initial SAR, and molecular modeling.	Mrl Rome
12419361	23	Design and synthesis of ethyl pyrrolidine-5,5-trans-lactams as inhibitors of hepatitis C virus NS3/4A protease.	Glaxosmithkline
12392743	17	Capped dipeptide alpha-ketoacid inhibitors of the HCV NS3 protease.	Irbm, Mrl Rome
12372533	69	P1 Phenethyl peptide boronic acid inhibitors of HCV NS3 protease.	Bristol-Myers Squibb Pharmaceutical Research Institute
12372517	92	Highly potent non-peptidic inhibitors of the HCV NS3/NS4A serine protease.	Celera
11909704	43	Azapeptides as inhibitors of the hepatitis C virus NS3 serine protease.	Schering-Plough Research Institute
11844706	30	Evolution, synthesis and SAR of tripeptide alpha-ketoacid inhibitors of the hepatitis C virus NS3/NS4A serine protease.	Irbm, Mrl Rome
11844705	13	A designed P1 cysteine mimetic for covalent and non-covalent inhibitors of HCV NS3 protease.	Irbm, Mrl Rome
11844690	8	Solution and solid-phase synthesis of potent inhibitors of hepatitis C virus NS3 proteinase.	Roche Discovery Welwyn
11527730	27	Structure-activity relationship studies of a bisbenzimidazole-based, Zn(2+)-dependent inhibitor of HCV NS3 serine protease.	Bristol-Myers Squibb Pharmaceutical Research Institute
11212109	14	The identification of alpha-ketoamides as potent inhibitors of hepatitis C virus NS3-4A proteinase.	Roche Discover Welwyn
11206478	18	Arylalkylidene rhodanine with bulky and hydrophobic functional group as selective HCV NS3 protease inhibitor.	Institute Of Molecular And Cell Biology
10782670	11	Alpha-ketoamides, alpha-ketoesters and alpha-diketones as HCV NS3 protease inhibitors.	Dupont Pharmaceuticals
9873610	48	Studies on the C-terminal of hexapeptide inhibitors of the hepatitis C virus serine protease.	Boehringer Ingelheim (Canada)
9171866	12	Potent noncovalent thrombin inhibitors that utilize the unique amino acid D-dicyclohexylalanine in the P3 position. Implications on oral bioavailability and antithrombotic efficacy.	Merck Research Laboratories
23023261	6	Discovery of an allosteric mechanism for the regulation of HCV NS3 protein function.	Astex Pharmaceuticals