The following articles (labelled with PubMed ID or TBD) are for your review
| PMID | Data | Article Title | Organization |
|---|
| 28040393 |
7 |
Synthesis and biological evaluation of naphthoquinone-coumarin conjugates as topoisomerase II inhibitors. |
Instituto Universitario De Bio-Org£Nica (Cibican) |
| 8410993 |
24 |
Mammalian topoisomerase II inhibitory activity of 1-cyclopropyl-6,8- difluoro-1,4-dihydro-7-(2,6-dimethyl-4-pyridinyl)-4-oxo-3-quinolinecarb oxylic acid and related derivatives. |
Sterling Winthrop Pharmaceuticals Research Division |
| 14980663 |
8 |
Novel quinazoline-quinoline alkaloids with cytotoxic and DNA topoisomerase II inhibitory activities. |
Toho University |
| 15125947 |
38 |
Design, synthesis and structure-activity relationship studies of novel indazole analogues as DNA gyrase inhibitors with Gram-positive antibacterial activity. |
Dainippon Pharmaceutical |
| 12824037 |
15 |
Synthesis and biological testing of non-fluorinated analogues of levofloxacin. |
Procter & Gamble Pharmaceuticals |
| 10698436 |
1 |
Preparation of 5-(2,6-dideoxy-2-fluoro-alpha-L-talopyranosyloxy)-6-hydroxynap htho[2,3- f]quinoline-7,12-dione (FT-Alz), a new-type, potentially antitumor substance with various biological activities. |
Institute Of Bioorganic Chemistry |
| 27521587 |
20 |
Quinolino[3,4-b]quinoxalines and pyridazino[4,3-c]quinoline derivatives: Synthesis, inhibition of topoisomerase IIa, G-quadruplex binding and cytotoxic properties. |
Universit£ |
| 26906637 |
2 |
Inhibition of human DNA topoisomerase IIa by two novel ellipticine derivatives. |
Vanderbilt University School Of Medicine |
| 26649766 |
2 |
Synthesis and Mechanism Studies of 1,3-Benzoazolyl Substituted Pyrrolo[2,3-b]pyrazine Derivatives as Nonintercalative Topoisomerase II Catalytic Inhibitors. |
Sun Yat-Sen University |
| 25799376 |
2 |
Structure-based hybridization, synthesis and biological evaluation of novel tetracyclic heterocyclic azathioxanthone analogues as potential antitumor agents. |
Taipei Medical University |
| 26216018 |
2 |
Imine/amide-imidazole conjugates derived from 5-amino-4-cyano-N1-substituted benzyl imidazole: Microwave-assisted synthesis and anticancer activity via selective topoisomerase-II-a inhibition. |
Central University Of Punjab |
| 26183545 |
47 |
4,6-Substituted-1,3,5-triazin-2(1H)-ones as monocyclic catalytic inhibitors of human DNA topoisomerase IIa targeting the ATP binding site. |
National Institute Of Chemistry |
| 25286019 |
18 |
Novel DNA gyrase inhibiting spiropyrimidinetriones with a benzisoxazole scaffold: SAR and in vivo characterization. |
Astrazeneca |
| 25941559 |
1 |
Switch in Site of Inhibition: A Strategy for Structure-Based Discovery of Human Topoisomerase IIa Catalytic Inhibitors. |
Department Of Pharmaceutical Technology (Biotechnology), Department Of Pharmacoinformatics, And Department Of Medicinal Chemistry, National Institute Of Pharmaceutical Education And Research (Niper |
| 25453816 |
27 |
Monocyclic 4-amino-6-(phenylamino)-1,3,5-triazines as inhibitors of human DNA topoisomerase IIa. |
National Institute Of Chemistry |
| 15808469 |
32 |
Inhibitory activities against topoisomerase I and II by isoaurostatin derivatives and their structure-activity relationships. |
Kumamoto University |
| 23092389 |
5 |
Lanostanoids from fungi: a group of potential anticancer compounds. |
TBA |
| 22483608 |
2 |
Synthesis and evaluation of 2-[2-(phenylthiomethyl)-1H-benzo[d] imidazol-1-yl)acetohydrazide derivatives as antitumor agents. |
Sichuan University |
| 20371180 |
122 |
Cytotoxicity and inhibition of DNA topoisomerase I of polyhydroxylated triterpenoids and triterpenoid glycosides. |
Stephen F. Austin State University |
| 20006518 |
2 |
A diazirine-based photoaffinity etoposide probe for labeling topoisomerase II. |
University Of Manitoba |
| 11754608 |
6 |
Screening of triterpenoids isolated from Phyllanthus flexuosus for DNA topoisomerase inhibitory activity. |
Osaka University Of Pharmaceutical Sciences |
| 18321715 |
15 |
Synthesis of 1-/2-substituted-[1,2,3]triazolo[4,5-g]phthalazine-4,9-diones and evaluation of their cytotoxicity and topoisomerase II inhibition. |
Ewha Womans University |
| 18077363 |
314 |
A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases. |
University Of Oxford |
| 18083028 |
5 |
Synthesis and biological evaluation of bengacarboline derivatives. |
Universit£ |
| 8765520 |
3 |
Design, synthesis, and biological evaluation of ellipticine-estradiol conjugates. |
Purdue University |
| | 46 |
The antitumor activity of novel pyrazoloquinoline derivatives |
TBA |
| 22014228 |
10 |
Catalytic inhibition of eukaryotic topoisomerases I and II by flavonol glycosides extracted from Vicia faba and Lotus edulis. |
University Of Thessaly |
| 22014547 |
2 |
Ungeremine effectively targets mammalian as well as bacterial type I and type II topoisomerases. |
University Of Cagliari |
| 21644529 |
2 |
N-fused imidazoles as novel anticancer agents that inhibit catalytic activity of topoisomerase IIa and induce apoptosis in G1/S phase. |
National Institute Of Pharmaceutical Education And Research (Niper) |
| 21600681 |
4 |
Synthesis and evaluation of mansonone F derivatives as topoisomerase inhibitors. |
Sun Yat-Sen University |
| 21391686 |
12 |
Role of metalation in the topoisomerase IIa inhibition and antiproliferation activity of a series ofa-heterocyclic-N4-substituted thiosemicarbazones and their Cu(II) complexes. |
Memorial Sloan-Kettering Cancer Center |
| 20353152 |
1 |
A series of alpha-heterocyclic carboxaldehyde thiosemicarbazones inhibit topoisomerase IIalpha catalytic activity. |
Chinese Academy Of Sciences |
| 19595598 |
2 |
7-((4-Substituted)piperazin-1-yl) derivatives of ciprofloxacin: synthesis and in vitro biological evaluation as potential antitumor agents. |
Universit£ |
| 19457675 |
8 |
The structure-based design, synthesis, and biological evaluation of DNA-binding amide linked bisintercalating bisanthrapyrazole anticancer compounds. |
University Of Manitoba |
| 19560355 |
2 |
Discovery of a new class of catalytic topoisomerase II inhibitors targeting the ATP-binding site by structure based design. Part I. |
Novartis Institutes For Biomedical Research |
| 19364657 |
11 |
Synthesis, cytotoxic activity, DNA topoisomerase-II inhibition, molecular modeling and structure-activity relationship of 9-anilinothiazolo[5,4-b]quinoline derivatives. |
Universidad Nacional AutóNoma De MéXico |
| 18258442 |
9 |
The structure-based design, synthesis and biological evaluation of DNA-binding bisintercalating bisanthrapyrazole anticancer compounds. |
University Of Manitoba |
| 12444693 |
5 |
Triterpenoid constituents isolated from the bark of Abies sachalinensis. |
Osaka University Of Pharmaceutical Sciences |
| 11678653 |
1 |
Catalytic inhibition of topoisomerase IIalpha by demethylzeylasterone, a 6-oxophenolic triterpenoid from Kokoona zeylanica. |
University Of Arizona |
| 11430001 |
72 |
Isoaurostatin, a novel topoisomerase inhibitor produced by Thermomonospora alba. |
Kumamoto University |
| 10757727 |
2 |
Three new triterpenoids from Peganum nigellastrum. |
Toho University |
| 9544566 |
1 |
DNA polymerase and topoisomerase II inhibitors from Psoralea corylifolia. |
Ohio State University |
| 15149679 |
6 |
Critical structural motif for the catalytic inhibition of human topoisomerase II by UK-1 and analogs. |
University Of Maryland |
| 15026047 |
29 |
Inhibitory activities against topoisomerase I and II by polyhydroxybenzoyl amide derivatives and their structure-activity relationship. |
Kumamoto University |
| 10743939 |
63 |
Synthesis and biological activities of NB-506 analogues modified at the glucose group. |
Banyu Tsukuba Research Institute |
| 10340602 |
100 |
Synthesis and biological activities of topoisomerase I inhibitors, 6-N-amino analogues of NB-506. |
Banyu Tsukuba Research Institute |
| 28342691 |
9 |
Indenocinnoline derivatives as G-quadruplex binders, topoisomerase II? inhibitors and antiproliferative agents. |
National And Kapodistrian University Of Athens |
Search and Browse
