The following articles (labelled with PubMed ID or TBD) are for your review
| PMID | Data | Article Title | Organization |
|---|
| 27353888 |
30 |
Design, synthesis and evaluation of novel indandione derivatives as multifunctional agents with cholinesterase inhibition, anti-ß-amyloid aggregation, antioxidant and neuroprotection properties against Alzheimer's disease. |
University Of Delhi |
| 27190601 |
71 |
Structure-Activity Relationship Studies of Isomeric 2,4-Diaminoquinazolines onß-Amyloid Aggregation Kinetics. |
University Of Waterloo |
| 27061983 |
48 |
Design, synthesis and evaluation of novel tacrine-multialkoxybenzene hybrids as multi-targeted compounds against Alzheimer's disease. |
Guangzhou Medical University |
| 26945113 |
9 |
Amyloid cascade in Alzheimer's disease: Recent advances in medicinal chemistry. |
University Of Waterloo |
| 26783181 |
24 |
Design and discovery of Novel Thiazole acetamide derivatives as anticholinesterase agent for possible role in the management of Alzheimer's. |
Linyi People'S Hospital |
| 26632651 |
70 |
Novel Tacrine-Benzofuran Hybrids as Potent Multitarget-Directed Ligands for the Treatment of Alzheimer's Disease: Design, Synthesis, Biological Evaluation, and X-ray Crystallography. |
China Pharmaceutical University |
| 26719209 |
7 |
Structural insights into mechanisms for inhibiting amyloidß42 aggregation by non-catechol-type flavonoids. |
Kyoto University |
| 26598460 |
14 |
Diversification of edaravone via palladium-catalyzed hydrazine cross-coupling: Applications against protein misfolding and oligomerization of beta-amyloid. |
Dalhousie University |
| 26288690 |
1 |
Highly Efficient Synthesis of 1,3-Dihydroxy-2-carboxycarbazole and Its Neuroprotective Effects. |
Virginia Commonwealth University |
| 26177091 |
138 |
Design, Synthesis, and Characterization of 3-(Benzylidene)indolin-2-one Derivatives as Ligands fora-Synuclein Fibrils. |
Washington University |
| 26099993 |
5 |
3,5-Diarylpyrazole Derivatives Obtained by Ammonolysis of the Total Flavonoids from Chrysanthemum indicum Extract Show Potential for the Treatment of Alzheimer's Disease. |
Sun Yat-Sen University |
| 26078011 |
7 |
NO-donor thiacarbocyanines as multifunctional agents for Alzheimer's disease. |
Universit£ |
| 25978520 |
9 |
Nodulisporiviridins A-H, Bioactive Viridins from Nodulisporium sp. |
Jinan University |
| 24878198 |
4 |
Naturally occurring polyphenolic inhibitors of amyloid beta aggregation. |
Csiro Manufacturing Flagship (Biomedical) |
| 24944730 |
20 |
Imidazo[2,1]thiazol-3-one Derivatives Useful as Diagnostic Agents for Alzheimer's Disease. |
Temple University |
| 24131448 |
7 |
Oxidative stress in Alzheimer's disease: are we connecting the dots? |
University Of Bologna |
| 24657049 |
5 |
Polyfluorinated bis-styrylbenzenes as amyloid-ß plaque binding ligands. |
Leiden University |
| 18954037 |
40 |
Structure-activity relationships of acetylcholinesterase noncovalent inhibitors based on a polyamine backbone. 4. Further investigation on the inner spacer. |
University Of Bologna |
| 18793854 |
25 |
Aminostyrylbenzofuran derivatives as potent inhibitors for Abeta fibril formation. |
Institute Of Science And Technology |
| 17004725 |
13 |
Curcumin and dehydrozingerone derivatives: synthesis, radiolabeling, and evaluation for beta-amyloid plaque imaging. |
Sungkyunkwan University School Of Medicine |
| 16162001 |
12 |
F-18 stilbenes as PET imaging agents for detecting beta-amyloid plaques in the brain. |
University Of Pennsylvania |
| 21145738 |
5 |
Diphenylpropynone derivatives as probes for imagingß-amyloid plaques in Alzheimer's brains. |
Kyoto University |
| 20223661 |
48 |
Novel pyrrolyl 2-aminopyridines as potent and selective human beta-secretase (BACE1) inhibitors. |
Wyeth |
| 19959359 |
46 |
Discovery and initial optimization of 5,5'-disubstituted aminohydantoins as potent beta-secretase (BACE1) inhibitors. |
Wyeth Research |
| 19275964 |
64 |
(3,3-Difluoro-pyrrolidin-1-yl)-[(2S,4S)-(4-(4-pyrimidin-2-yl-piperazin-1-yl)-pyrrolidin-2-yl]-methanone: a potent, selective, orally active dipeptidyl peptidase IV inhibitor. |
Pfizer |
| 17761417 |
50 |
Small conformationally restricted piperidine N-arylsulfonamides as orally active gamma-secretase inhibitors. |
Schering-Plough Research Institute |
| 17418571 |
23 |
Design, synthesis, and evaluation of tetrahydroquinoline and pyrrolidine sulfonamide carbamates as gamma-secretase inhibitors. |
Pharmacopeia Drug Discovery |
| 16640346 |
24 |
Synthesis of biphenyltrienes as probes for beta-amyloid plaques. |
University Of Pennsylvania |
| 16640332 |
8 |
Novel benzofuran derivatives for PET imaging of beta-amyloid plaques in Alzheimer's disease brains. |
Nagasaki University |
| 16574411 |
4 |
Synthesis and evaluation of two 18F-labeled imidazo[1,2-a]pyridine analogues as potential agents for imaging beta-amyloid in Alzheimer's disease. |
Emory University |
| 16473009 |
23 |
Synthesis and evaluation of succinoyl-caprolactam gamma-secretase inhibitors. |
Bristol-Myers Squibb Pharmaceutical Research Institute |
| 16325402 |
15 |
Design, synthesis, and structure-activity relationship of novel thiophene derivatives for beta-amyloid plaque imaging. |
University Of Pennsylvania |
| 16279784 |
12 |
Radioiodinated flavones for in vivo imaging of beta-amyloid plaques in the brain. |
Nagasaki University |
| 16134939 |
67 |
Synthesis and biological activity of flurbiprofen analogues as selective inhibitors of beta-amyloid(1)(-)(42) secretion. |
Chiesi Farmaceutici |
| 15780628 |
15 |
Molecular-modeling based design, synthesis, and activity of substituted piperidines as gamma-secretase inhibitors. |
Wyeth Research |
| 12801237 |
19 |
Synthesis and evaluation of 11C-labeled 6-substituted 2-arylbenzothiazoles as amyloid imaging agents. |
University Of Pittsburgh |
| 12519062 |
11 |
Structure-activity relationship of imidazo[1,2-a]pyridines as ligands for detecting beta-amyloid plaques in the brain. |
University Of Pennsylvania |
| 11428920 |
6 |
Isomerization of (Z,Z) to (E,E)1-bromo-2,5-bis-(3-hydroxycarbonyl-4-hydroxy)styrylbenzene in strong base: probes for amyloid plaques in the brain. |
University Of Pennsylvania |
| 11384236 |
26 |
Radioiodinated styrylbenzenes and thioflavins as probes for amyloid aggregates. |
University Of Pennsylvania |
| 10882355 |
5 |
Fenchylamine sulfonamide inhibitors of amyloid beta peptide production by the gamma-secretase proteolytic pathway: potential small-molecule therapeutic agents for the treatment of Alzheimer's disease. |
Amgen |
| 28169518 |
6 |
Fragment Profiling Approach to Inhibitors of the Orphan M. tuberculosis P450 CYP144A1. |
University Of Cambridge |
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