Compile Data Set for Download or QSAR

Found 48 hits with Last Name = 'addlagatta' and Initial = 'a'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Methionine aminopeptidase 1 (Homo sapiens (Human))	BDBM50078539 (CHEMBL3414950) Show SMILES CCCC(CCC)C(N)P(O)(O)=O Show InChI InChI=1S/C8H20NO3P/c1-3-5-7(6-4-2)8(9)13(10,11)12/h7-8H,3-6,9H2,1-2H3,(H2,10,11,12)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	PDB Article PubMed	4.90E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
CSIR-Indian Institute of Chemical Technology Curated by ChEMBL					Assay Description Inhibition of Human MetAP1b using Met-pNA as substrate				J Med Chem 58: 2350-7 (2015) Article DOI: 10.1021/jm501790e BindingDB Entry DOI: 10.7270/Q2C53NJX
					More data for this Ligand-Target Pair				3D Structure (crystal)
Methionine aminopeptidase 1 (Homo sapiens (Human))	BDBM50337147 ((RS)-1-amino-3-cyclohexylpropylphosphonic acid | C...) Show SMILES NC(CCC1CCCCC1)P(O)(O)=O Show InChI InChI=1S/C9H20NO3P/c10-9(14(11,12)13)7-6-8-4-2-1-3-5-8/h8-9H,1-7,10H2,(H2,11,12,13)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9.90E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
CSIR-Indian Institute of Chemical Technology Curated by ChEMBL					Assay Description Inhibition of Human MetAP1b using Met-pNA as substrate				J Med Chem 58: 2350-7 (2015) Article DOI: 10.1021/jm501790e BindingDB Entry DOI: 10.7270/Q2C53NJX
					More data for this Ligand-Target Pair
Methionine aminopeptidase 1 (Homo sapiens (Human))	BDBM50078540 (CHEMBL1673077) Show SMILES CCCC(C)C(N)P(O)(O)=O Show InChI InChI=1S/C6H16NO3P/c1-3-4-5(2)6(7)11(8,9)10/h5-6H,3-4,7H2,1-2H3,(H2,8,9,10)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	PDB Article PubMed	5.48E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
CSIR-Indian Institute of Chemical Technology Curated by ChEMBL					Assay Description Inhibition of Human MetAP1b using Met-pNA as substrate				J Med Chem 58: 2350-7 (2015) Article DOI: 10.1021/jm501790e BindingDB Entry DOI: 10.7270/Q2C53NJX
					More data for this Ligand-Target Pair				3D Structure (crystal)
Methionine aminopeptidase 1 (Homo sapiens (Human))	BDBM50316031 (CHEMBL1090366 | amino(phenyl)methylphosphonic acid) Show SMILES NC(c1ccccc1)P(O)(O)=O Show InChI InChI=1S/C7H10NO3P/c8-7(12(9,10)11)6-4-2-1-3-5-6/h1-5,7H,8H2,(H2,9,10,11)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	1.12E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
CSIR-Indian Institute of Chemical Technology Curated by ChEMBL					Assay Description Inhibition of Human MetAP1b using Met-pNA as substrate				J Med Chem 58: 2350-7 (2015) Article DOI: 10.1021/jm501790e BindingDB Entry DOI: 10.7270/Q2C53NJX
					More data for this Ligand-Target Pair				3D Structure (crystal)
Methionine aminopeptidase 1 (Homo sapiens (Human))	BDBM50078541 (CHEMBL3414949) Show SMILES NC(C1CCCCC1)P(O)(O)=O Show InChI InChI=1S/C7H16NO3P/c8-7(12(9,10)11)6-4-2-1-3-5-6/h6-7H,1-5,8H2,(H2,9,10,11)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	PDB Article PubMed	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
CSIR-Indian Institute of Chemical Technology Curated by ChEMBL					Assay Description Inhibition of Human MetAP1b using Met-pNA as substrate				J Med Chem 58: 2350-7 (2015) Article DOI: 10.1021/jm501790e BindingDB Entry DOI: 10.7270/Q2C53NJX
					More data for this Ligand-Target Pair				3D Structure (crystal)
Methionine aminopeptidase 1 (Homo sapiens (Human))	BDBM50337150 ((RS)-1-amino-2-cyclohexylethylphosphonic acid | CH...) Show SMILES NC(CC1CCCCC1)P(O)(O)=O Show InChI InChI=1S/C8H18NO3P/c9-8(13(10,11)12)6-7-4-2-1-3-5-7/h7-8H,1-6,9H2,(H2,10,11,12)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	PDB Article PubMed	>5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
CSIR-Indian Institute of Chemical Technology Curated by ChEMBL					Assay Description Inhibition of Human MetAP1b using Met-pNA as substrate				J Med Chem 58: 2350-7 (2015) Article DOI: 10.1021/jm501790e BindingDB Entry DOI: 10.7270/Q2C53NJX
					More data for this Ligand-Target Pair				3D Structure (crystal)
Methionine aminopeptidase 1 (Homo sapiens (Human))	BDBM17847 (CHEMBL327579 | pyridine-2-carboxylic acid inhibito...) Show SMILES CC(C)(C)OC(=O)Nc1cccnc1C(=O)Nc1nccs1 Show InChI InChI=1S/C14H16N4O3S/c1-14(2,3)21-13(20)17-9-5-4-6-15-10(9)11(19)18-12-16-7-8-22-12/h4-8H,1-3H3,(H,17,20)(H,16,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank MMDB PDB Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	7.5	22
Johns Hopkins University					Assay Description The MetAP reaction with Co2+ as a cofactor is coupled to a prolyl aminopeptidase (ProAP) using Met-Pro-p-nitroanilide as substrate. MetAP-catalyzed c...				Proc Natl Acad Sci U S A 103: 18148-53 (2006) Article DOI: 10.1073/pnas.0608389103 BindingDB Entry DOI: 10.7270/Q2RB72VK
					More data for this Ligand-Target Pair				3D Structure (crystal)
Similar to alpha-tubulin isoform 1/Tubulin beta-2B chain (Bos taurus)	BDBM50014846 ((S)-N-(5,6,7,9-tetrahydro-1,2,3,10-tetramethoxy-9-...) Show SMILES COc1cc2CC[C@H](NC(C)=O)c3cc(=O)c(OC)ccc3-c2c(OC)c1OC |r| Show InChI InChI=1S/C22H25NO6/c1-12(24)23-16-8-6-13-10-19(27-3)21(28-4)22(29-5)20(13)14-7-9-18(26-2)17(25)11-15(14)16/h7,9-11,16H,6,8H2,1-5H3,(H,23,24)/t16-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
CSIR-Indian Institute of Chemical Technology Curated by ChEMBL					Assay Description Inhibition of bovine brain tubulin polymerization measured for 1 hr by fluorescence assay				Eur J Med Chem 90: 603-19 (2015) Article DOI: 10.1016/j.ejmech.2014.11.063 BindingDB Entry DOI: 10.7270/Q2ZG6TXF
					More data for this Ligand-Target Pair				3D Structure (crystal)
Puromycin-sensitive aminopeptidase (Homo sapiens (Human))	BDBM50499710 (CHEMBL516021) Show SMILES CCOC(=O)C1=C(CC(N(C1c1cccnc1)c1ccccc1)c1cccnc1)Nc1ccccc1 |t:5| Show InChI InChI=1S/C30H28N4O2/c1-2-36-30(35)28-26(33-24-13-5-3-6-14-24)19-27(22-11-9-17-31-20-22)34(25-15-7-4-8-16-25)29(28)23-12-10-18-32-21-23/h3-18,20-21,27,29,33H,2,19H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.79E+3	n/a	n/a	n/a	n/a	n/a	n/a
CSIR-Indian Institute of Chemical Technology Curated by ChEMBL					Assay Description Inhibition of recombinant human puromycin sensitive aminopeptidase using Leu-pNA as substrate after 30 mins				Eur J Med Chem 106: 26-33 (2015) Article DOI: 10.1016/j.ejmech.2015.10.026 BindingDB Entry DOI: 10.7270/Q2FF3WCZ
					More data for this Ligand-Target Pair
Puromycin-sensitive aminopeptidase (Homo sapiens (Human))	BDBM50277158 (3123L | CHEBI:17939 | CL-13900 | GNF-Pf-2016 | P-6...) Show SMILES COc1ccc(C[C@H](N)C(=O)N[C@@H]2[C@@H](CO)O[C@H]([C@@H]2O)n2cnc3c(ncnc23)N(C)C)cc1 |r| Show InChI InChI=1S/C22H29N7O5/c1-28(2)19-17-20(25-10-24-19)29(11-26-17)22-18(31)16(15(9-30)34-22)27-21(32)14(23)8-12-4-6-13(33-3)7-5-12/h4-7,10-11,14-16,18,22,30-31H,8-9,23H2,1-3H3,(H,27,32)/t14-,15+,16+,18+,22+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	2.45E+3	n/a	n/a	n/a	n/a	n/a	n/a
CSIR-Indian Institute of Chemical Technology Curated by ChEMBL					Assay Description Inhibition of recombinant human puromycin sensitive aminopeptidase using Leu-pNA as substrate after 30 mins				Eur J Med Chem 106: 26-33 (2015) Article DOI: 10.1016/j.ejmech.2015.10.026 BindingDB Entry DOI: 10.7270/Q2FF3WCZ
					More data for this Ligand-Target Pair
Methionine aminopeptidase 1 (Homo sapiens (Human))	BDBM17849 (3-(2,2-dimethylpropanamido)-N-(1,3-thiazol-2-yl)py...) Show SMILES CC(C)(C)C(=O)Nc1cccnc1C(=O)Nc1nccs1 Show InChI InChI=1S/C14H16N4O2S/c1-14(2,3)12(20)17-9-5-4-6-15-10(9)11(19)18-13-16-7-8-21-13/h4-8H,1-3H3,(H,17,20)(H,16,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Similars	DrugBank MMDB PDB Article PubMed	n/a	n/a	2.90E+3	n/a	n/a	n/a	n/a	7.5	22
Johns Hopkins University					Assay Description The MetAP reaction with Co2+ as a cofactor is coupled to a prolyl aminopeptidase (ProAP) using Met-Pro-p-nitroanilide as substrate. MetAP-catalyzed c...				Proc Natl Acad Sci U S A 103: 18148-53 (2006) Article DOI: 10.1073/pnas.0608389103 BindingDB Entry DOI: 10.7270/Q2RB72VK
					More data for this Ligand-Target Pair				3D Structure (crystal)
Methionine aminopeptidase 1 (Homo sapiens (Human))	BDBM17850 (3-(3-phenylpropanamido)-N-(1,3-thiazol-2-yl)pyridi...) Show SMILES O=C(CCc1ccccc1)Nc1cccnc1C(=O)Nc1nccs1 Show InChI InChI=1S/C18H16N4O2S/c23-15(9-8-13-5-2-1-3-6-13)21-14-7-4-10-19-16(14)17(24)22-18-20-11-12-25-18/h1-7,10-12H,8-9H2,(H,21,23)(H,20,22,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.50E+3	n/a	n/a	n/a	n/a	7.5	22
Johns Hopkins University					Assay Description The MetAP reaction with Co2+ as a cofactor is coupled to a prolyl aminopeptidase (ProAP) using Met-Pro-p-nitroanilide as substrate. MetAP-catalyzed c...				Proc Natl Acad Sci U S A 103: 18148-53 (2006) Article DOI: 10.1073/pnas.0608389103 BindingDB Entry DOI: 10.7270/Q2RB72VK
					More data for this Ligand-Target Pair
Methionine aminopeptidase 1 (Homo sapiens (Human))	BDBM17851 (3-[(E)-(2-methylpropylidene)amino]-N-(1,3-thiazol-...) Show SMILES CC(C)C=Nc1cccnc1C(=O)Nc1nccs1 |w:4.4| Show InChI InChI=1S/C13H14N4OS/c1-9(2)8-16-10-4-3-5-14-11(10)12(18)17-13-15-6-7-19-13/h3-9H,1-2H3,(H,15,17,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.40E+3	n/a	n/a	n/a	n/a	7.5	22
Johns Hopkins University					Assay Description The MetAP reaction with Co2+ as a cofactor is coupled to a prolyl aminopeptidase (ProAP) using Met-Pro-p-nitroanilide as substrate. MetAP-catalyzed c...				Proc Natl Acad Sci U S A 103: 18148-53 (2006) Article DOI: 10.1073/pnas.0608389103 BindingDB Entry DOI: 10.7270/Q2RB72VK
					More data for this Ligand-Target Pair
Similar to alpha-tubulin isoform 1/Tubulin beta-2B chain (Bos taurus)	BDBM50062530 (CHEMBL3397584) Show SMILES COc1cc(cc(OC)c1OC)C1=NOC(COCc2cn(Cc3cc(cnc3Cl)-c3ccccc3)nn2)C1 |t:13| Show InChI InChI=1S/C28H28ClN5O5/c1-35-25-10-19(11-26(36-2)27(25)37-3)24-12-23(39-32-24)17-38-16-22-15-34(33-31-22)14-21-9-20(13-30-28(21)29)18-7-5-4-6-8-18/h4-11,13,15,23H,12,14,16-17H2,1-3H3	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
CSIR-Indian Institute of Chemical Technology Curated by ChEMBL					Assay Description Inhibition of bovine brain tubulin polymerization measured for 1 hr by fluorescence assay				Eur J Med Chem 90: 603-19 (2015) Article DOI: 10.1016/j.ejmech.2014.11.063 BindingDB Entry DOI: 10.7270/Q2ZG6TXF
					More data for this Ligand-Target Pair
Puromycin-sensitive aminopeptidase (Homo sapiens (Human))	BDBM50499702 (CHEMBL3740370) Show SMILES CCOC(=O)C1C(N(C(CC1=O)c1cccnc1)c1ccccc1)c1cccnc1 Show InChI InChI=1S/C24H23N3O3/c1-2-30-24(29)22-21(28)14-20(17-8-6-12-25-15-17)27(19-10-4-3-5-11-19)23(22)18-9-7-13-26-16-18/h3-13,15-16,20,22-23H,2,14H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.04E+3	n/a	n/a	n/a	n/a	n/a	n/a
CSIR-Indian Institute of Chemical Technology Curated by ChEMBL					Assay Description Inhibition of recombinant human puromycin sensitive aminopeptidase using Leu-pNA as substrate after 30 mins				Eur J Med Chem 106: 26-33 (2015) Article DOI: 10.1016/j.ejmech.2015.10.026 BindingDB Entry DOI: 10.7270/Q2FF3WCZ
					More data for this Ligand-Target Pair
Similar to alpha-tubulin isoform 1/Tubulin beta-2B chain (Bos taurus)	BDBM50062531 (CHEMBL3397585) Show SMILES COc1cc(cc(OC)c1OC)C1=NOC(COCc2cn(Cc3cc(cnc3Cl)-c3ccc(C)cc3)nn2)C1 |t:13| Show InChI InChI=1S/C29H30ClN5O5/c1-18-5-7-19(8-6-18)21-9-22(29(30)31-13-21)14-35-15-23(32-34-35)16-39-17-24-12-25(33-40-24)20-10-26(36-2)28(38-4)27(11-20)37-3/h5-11,13,15,24H,12,14,16-17H2,1-4H3	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
CSIR-Indian Institute of Chemical Technology Curated by ChEMBL					Assay Description Inhibition of bovine brain tubulin polymerization measured for 1 hr by fluorescence assay				Eur J Med Chem 90: 603-19 (2015) Article DOI: 10.1016/j.ejmech.2014.11.063 BindingDB Entry DOI: 10.7270/Q2ZG6TXF
					More data for this Ligand-Target Pair
Puromycin-sensitive aminopeptidase (Homo sapiens (Human))	BDBM50499709 (CHEMBL3741560) Show SMILES CCOC(=O)C1=C(CC(N(C1c1ccccn1)c1ccc(C)cc1)c1ccccc1)Nc1ccc(C)cc1 |t:5| Show InChI InChI=1S/C33H33N3O2/c1-4-38-33(37)31-29(35-26-17-13-23(2)14-18-26)22-30(25-10-6-5-7-11-25)36(27-19-15-24(3)16-20-27)32(31)28-12-8-9-21-34-28/h5-21,30,32,35H,4,22H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.53E+3	n/a	n/a	n/a	n/a	n/a	n/a
CSIR-Indian Institute of Chemical Technology Curated by ChEMBL					Assay Description Inhibition of recombinant human puromycin sensitive aminopeptidase using Leu-pNA as substrate after 30 mins				Eur J Med Chem 106: 26-33 (2015) Article DOI: 10.1016/j.ejmech.2015.10.026 BindingDB Entry DOI: 10.7270/Q2FF3WCZ
					More data for this Ligand-Target Pair
Puromycin-sensitive aminopeptidase (Homo sapiens (Human))	BDBM50499705 (CHEMBL3741724) Show SMILES CCOC(=O)C1=C(CC(N(C1c1cccnc1)c1ccccc1)c1ccc(cc1)C#N)Nc1ccccc1 |t:5| Show InChI InChI=1S/C32H28N4O2/c1-2-38-32(37)30-28(35-26-11-5-3-6-12-26)20-29(24-17-15-23(21-33)16-18-24)36(27-13-7-4-8-14-27)31(30)25-10-9-19-34-22-25/h3-19,22,29,31,35H,2,20H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.02E+4	n/a	n/a	n/a	n/a	n/a	n/a
CSIR-Indian Institute of Chemical Technology Curated by ChEMBL					Assay Description Inhibition of recombinant human puromycin sensitive aminopeptidase using Leu-pNA as substrate after 30 mins				Eur J Med Chem 106: 26-33 (2015) Article DOI: 10.1016/j.ejmech.2015.10.026 BindingDB Entry DOI: 10.7270/Q2FF3WCZ
					More data for this Ligand-Target Pair
Puromycin-sensitive aminopeptidase (Homo sapiens (Human))	BDBM50499712 (CHEMBL3741833) Show SMILES CCOC(=O)C1=C(CC(N(C1c1ccccn1)c1ccccc1)c1ccc(cc1)C#N)Nc1ccccc1 |t:5| Show InChI InChI=1S/C32H28N4O2/c1-2-38-32(37)30-28(35-25-11-5-3-6-12-25)21-29(24-18-16-23(22-33)17-19-24)36(26-13-7-4-8-14-26)31(30)27-15-9-10-20-34-27/h3-20,29,31,35H,2,21H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.27E+4	n/a	n/a	n/a	n/a	n/a	n/a
CSIR-Indian Institute of Chemical Technology Curated by ChEMBL					Assay Description Inhibition of recombinant human puromycin sensitive aminopeptidase using Leu-pNA as substrate after 30 mins				Eur J Med Chem 106: 26-33 (2015) Article DOI: 10.1016/j.ejmech.2015.10.026 BindingDB Entry DOI: 10.7270/Q2FF3WCZ
					More data for this Ligand-Target Pair
Puromycin-sensitive aminopeptidase (Homo sapiens (Human))	BDBM50499707 (CHEMBL3741904) Show SMILES OC1=CC(N(C(C1)c1cccnc1)c1ccccc1)c1cccnc1 |t:1| Show InChI InChI=1S/C21H19N3O/c25-19-12-20(16-6-4-10-22-14-16)24(18-8-2-1-3-9-18)21(13-19)17-7-5-11-23-15-17/h1-12,14-15,20-21,25H,13H2	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.63E+4	n/a	n/a	n/a	n/a	n/a	n/a
CSIR-Indian Institute of Chemical Technology Curated by ChEMBL					Assay Description Inhibition of recombinant human puromycin sensitive aminopeptidase using Leu-pNA as substrate after 30 mins				Eur J Med Chem 106: 26-33 (2015) Article DOI: 10.1016/j.ejmech.2015.10.026 BindingDB Entry DOI: 10.7270/Q2FF3WCZ
					More data for this Ligand-Target Pair
Puromycin-sensitive aminopeptidase (Homo sapiens (Human))	BDBM50499708 (CHEMBL3739649) Show SMILES OC1=CC(N(C(C1)c1ccccn1)c1ccccc1)c1ccccn1 |t:1| Show InChI InChI=1S/C21H19N3O/c25-17-14-20(18-10-4-6-12-22-18)24(16-8-2-1-3-9-16)21(15-17)19-11-5-7-13-23-19/h1-14,20-21,25H,15H2	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.64E+4	n/a	n/a	n/a	n/a	n/a	n/a
CSIR-Indian Institute of Chemical Technology Curated by ChEMBL					Assay Description Inhibition of recombinant human puromycin sensitive aminopeptidase using Leu-pNA as substrate after 30 mins				Eur J Med Chem 106: 26-33 (2015) Article DOI: 10.1016/j.ejmech.2015.10.026 BindingDB Entry DOI: 10.7270/Q2FF3WCZ
					More data for this Ligand-Target Pair
Puromycin-sensitive aminopeptidase (Homo sapiens (Human))	BDBM50499706 (CHEMBL3740199) Show SMILES CCOC(=O)C1=C(CC(N(C1c1cccnc1)c1ccccc1)c1cc(OC)c(OC)c(OC)c1)Nc1ccccc1 |t:5| Show InChI InChI=1S/C34H35N3O5/c1-5-42-34(38)31-27(36-25-14-8-6-9-15-25)21-28(24-19-29(39-2)33(41-4)30(20-24)40-3)37(26-16-10-7-11-17-26)32(31)23-13-12-18-35-22-23/h6-20,22,28,32,36H,5,21H2,1-4H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
CSIR-Indian Institute of Chemical Technology Curated by ChEMBL					Assay Description Inhibition of recombinant human puromycin sensitive aminopeptidase using Leu-pNA as substrate after 30 mins				Eur J Med Chem 106: 26-33 (2015) Article DOI: 10.1016/j.ejmech.2015.10.026 BindingDB Entry DOI: 10.7270/Q2FF3WCZ
					More data for this Ligand-Target Pair
Puromycin-sensitive aminopeptidase (Homo sapiens (Human))	BDBM50499704 (CHEMBL3740158) Show SMILES COC(=O)C1=C(CC(N(C1c1ccc(cc1)[N+]([O-])=O)c1ccccc1)c1ccc(cc1)[N+]([O-])=O)Nc1ccccc1 |t:4| Show InChI InChI=1S/C31H26N4O6/c1-41-31(36)29-27(32-23-8-4-2-5-9-23)20-28(21-12-16-25(17-13-21)34(37)38)33(24-10-6-3-7-11-24)30(29)22-14-18-26(19-15-22)35(39)40/h2-19,28,30,32H,20H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.88E+4	n/a	n/a	n/a	n/a	n/a	n/a
CSIR-Indian Institute of Chemical Technology Curated by ChEMBL					Assay Description Inhibition of recombinant human puromycin sensitive aminopeptidase using Leu-pNA as substrate after 30 mins				Eur J Med Chem 106: 26-33 (2015) Article DOI: 10.1016/j.ejmech.2015.10.026 BindingDB Entry DOI: 10.7270/Q2FF3WCZ
					More data for this Ligand-Target Pair
Puromycin-sensitive aminopeptidase (Homo sapiens (Human))	BDBM50499713 (CHEMBL3741344) Show SMILES CCOC(=O)C1=C(CC(N(C1c1cccs1)c1ccccc1)c1ccc(Br)cc1)Nc1ccccc1 |t:5| Show InChI InChI=1S/C30H27BrN2O2S/c1-2-35-30(34)28-25(32-23-10-5-3-6-11-23)20-26(21-15-17-22(31)18-16-21)33(24-12-7-4-8-13-24)29(28)27-14-9-19-36-27/h3-19,26,29,32H,2,20H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
CSIR-Indian Institute of Chemical Technology Curated by ChEMBL					Assay Description Inhibition of recombinant human puromycin sensitive aminopeptidase using Leu-pNA as substrate after 30 mins				Eur J Med Chem 106: 26-33 (2015) Article DOI: 10.1016/j.ejmech.2015.10.026 BindingDB Entry DOI: 10.7270/Q2FF3WCZ
					More data for this Ligand-Target Pair
Puromycin-sensitive aminopeptidase (Homo sapiens (Human))	BDBM50499701 (CHEMBL3741701) Show SMILES CCOC(=O)C1=C(CC(N(C1c1ccccn1)c1ccccc1)c1ccccn1)Nc1ccccc1 |t:5| Show InChI InChI=1S/C30H28N4O2/c1-2-36-30(35)28-26(33-22-13-5-3-6-14-22)21-27(24-17-9-11-19-31-24)34(23-15-7-4-8-16-23)29(28)25-18-10-12-20-32-25/h3-20,27,29,33H,2,21H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.25E+4	n/a	n/a	n/a	n/a	n/a	n/a
CSIR-Indian Institute of Chemical Technology Curated by ChEMBL					Assay Description Inhibition of recombinant human puromycin sensitive aminopeptidase using Leu-pNA as substrate after 30 mins				Eur J Med Chem 106: 26-33 (2015) Article DOI: 10.1016/j.ejmech.2015.10.026 BindingDB Entry DOI: 10.7270/Q2FF3WCZ
					More data for this Ligand-Target Pair
Puromycin-sensitive aminopeptidase (Homo sapiens (Human))	BDBM50499703 (CHEMBL3740862) Show SMILES CCOC(=O)C1C(N(C(CC1=O)c1ccccn1)c1ccccc1)c1ccccn1 Show InChI InChI=1S/C24H23N3O3/c1-2-30-24(29)22-21(28)16-20(18-12-6-8-14-25-18)27(17-10-4-3-5-11-17)23(22)19-13-7-9-15-26-19/h3-15,20,22-23H,2,16H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.29E+4	n/a	n/a	n/a	n/a	n/a	n/a
CSIR-Indian Institute of Chemical Technology Curated by ChEMBL					Assay Description Inhibition of recombinant human puromycin sensitive aminopeptidase using Leu-pNA as substrate after 30 mins				Eur J Med Chem 106: 26-33 (2015) Article DOI: 10.1016/j.ejmech.2015.10.026 BindingDB Entry DOI: 10.7270/Q2FF3WCZ
					More data for this Ligand-Target Pair
Puromycin-sensitive aminopeptidase (Homo sapiens (Human))	BDBM50499711 (CHEMBL3741419) Show SMILES CCOC(=O)C1=C(CC(N(C1c1cccnc1)c1ccccc1)c1ccc(Cl)cc1)Nc1ccccc1 |t:5| Show InChI InChI=1S/C31H28ClN3O2/c1-2-37-31(36)29-27(34-25-11-5-3-6-12-25)20-28(22-15-17-24(32)18-16-22)35(26-13-7-4-8-14-26)30(29)23-10-9-19-33-21-23/h3-19,21,28,30,34H,2,20H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.82E+4	n/a	n/a	n/a	n/a	n/a	n/a
CSIR-Indian Institute of Chemical Technology Curated by ChEMBL					Assay Description Inhibition of recombinant human puromycin sensitive aminopeptidase using Leu-pNA as substrate after 30 mins				Eur J Med Chem 106: 26-33 (2015) Article DOI: 10.1016/j.ejmech.2015.10.026 BindingDB Entry DOI: 10.7270/Q2FF3WCZ
					More data for this Ligand-Target Pair
Aminopeptidase N (Sus scrofa (Pig))	BDBM50499709 (CHEMBL3741560) Show SMILES CCOC(=O)C1=C(CC(N(C1c1ccccn1)c1ccc(C)cc1)c1ccccc1)Nc1ccc(C)cc1 |t:5| Show InChI InChI=1S/C33H33N3O2/c1-4-38-33(37)31-29(35-26-17-13-23(2)14-18-26)22-30(25-10-6-5-7-11-25)36(27-19-15-24(3)16-20-27)32(31)28-12-8-9-21-34-28/h5-21,30,32,35H,4,22H2,1-3H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
CSIR-Indian Institute of Chemical Technology Curated by ChEMBL					Assay Description Inhibition of porcine aminopeptidase-N using Leu-pNA as substrate after 30 mins				Eur J Med Chem 106: 26-33 (2015) Article DOI: 10.1016/j.ejmech.2015.10.026 BindingDB Entry DOI: 10.7270/Q2FF3WCZ
					More data for this Ligand-Target Pair
Aminopeptidase N (Sus scrofa (Pig))	BDBM50277158 (3123L | CHEBI:17939 | CL-13900 | GNF-Pf-2016 | P-6...) Show SMILES COc1ccc(C[C@H](N)C(=O)N[C@@H]2[C@@H](CO)O[C@H]([C@@H]2O)n2cnc3c(ncnc23)N(C)C)cc1 |r| Show InChI InChI=1S/C22H29N7O5/c1-28(2)19-17-20(25-10-24-19)29(11-26-17)22-18(31)16(15(9-30)34-22)27-21(32)14(23)8-12-4-6-13(33-3)7-5-12/h4-7,10-11,14-16,18,22,30-31H,8-9,23H2,1-3H3,(H,27,32)/t14-,15+,16+,18+,22+/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
CSIR-Indian Institute of Chemical Technology Curated by ChEMBL					Assay Description Inhibition of porcine aminopeptidase-N using Leu-pNA as substrate after 30 mins				Eur J Med Chem 106: 26-33 (2015) Article DOI: 10.1016/j.ejmech.2015.10.026 BindingDB Entry DOI: 10.7270/Q2FF3WCZ
					More data for this Ligand-Target Pair
Aminopeptidase N (Sus scrofa (Pig))	BDBM50499706 (CHEMBL3740199) Show SMILES CCOC(=O)C1=C(CC(N(C1c1cccnc1)c1ccccc1)c1cc(OC)c(OC)c(OC)c1)Nc1ccccc1 |t:5| Show InChI InChI=1S/C34H35N3O5/c1-5-42-34(38)31-27(36-25-14-8-6-9-15-25)21-28(24-19-29(39-2)33(41-4)30(20-24)40-3)37(26-16-10-7-11-17-26)32(31)23-13-12-18-35-22-23/h6-20,22,28,32,36H,5,21H2,1-4H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
CSIR-Indian Institute of Chemical Technology Curated by ChEMBL					Assay Description Inhibition of porcine aminopeptidase-N using Leu-pNA as substrate after 30 mins				Eur J Med Chem 106: 26-33 (2015) Article DOI: 10.1016/j.ejmech.2015.10.026 BindingDB Entry DOI: 10.7270/Q2FF3WCZ
					More data for this Ligand-Target Pair
Aminopeptidase N (Sus scrofa (Pig))	BDBM50499705 (CHEMBL3741724) Show SMILES CCOC(=O)C1=C(CC(N(C1c1cccnc1)c1ccccc1)c1ccc(cc1)C#N)Nc1ccccc1 |t:5| Show InChI InChI=1S/C32H28N4O2/c1-2-38-32(37)30-28(35-26-11-5-3-6-12-26)20-29(24-17-15-23(21-33)16-18-24)36(27-13-7-4-8-14-27)31(30)25-10-9-19-34-22-25/h3-19,22,29,31,35H,2,20H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
CSIR-Indian Institute of Chemical Technology Curated by ChEMBL					Assay Description Inhibition of porcine aminopeptidase-N using Leu-pNA as substrate after 30 mins				Eur J Med Chem 106: 26-33 (2015) Article DOI: 10.1016/j.ejmech.2015.10.026 BindingDB Entry DOI: 10.7270/Q2FF3WCZ
					More data for this Ligand-Target Pair
Aminopeptidase N (Sus scrofa (Pig))	BDBM50499704 (CHEMBL3740158) Show SMILES COC(=O)C1=C(CC(N(C1c1ccc(cc1)[N+]([O-])=O)c1ccccc1)c1ccc(cc1)[N+]([O-])=O)Nc1ccccc1 |t:4| Show InChI InChI=1S/C31H26N4O6/c1-41-31(36)29-27(32-23-8-4-2-5-9-23)20-28(21-12-16-25(17-13-21)34(37)38)33(24-10-6-3-7-11-24)30(29)22-14-18-26(19-15-22)35(39)40/h2-19,28,30,32H,20H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
CSIR-Indian Institute of Chemical Technology Curated by ChEMBL					Assay Description Inhibition of porcine aminopeptidase-N using Leu-pNA as substrate after 30 mins				Eur J Med Chem 106: 26-33 (2015) Article DOI: 10.1016/j.ejmech.2015.10.026 BindingDB Entry DOI: 10.7270/Q2FF3WCZ
					More data for this Ligand-Target Pair
Aminopeptidase N (Sus scrofa (Pig))	BDBM50499708 (CHEMBL3739649) Show SMILES OC1=CC(N(C(C1)c1ccccn1)c1ccccc1)c1ccccn1 |t:1| Show InChI InChI=1S/C21H19N3O/c25-17-14-20(18-10-4-6-12-22-18)24(16-8-2-1-3-9-16)21(15-17)19-11-5-7-13-23-19/h1-14,20-21,25H,15H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
CSIR-Indian Institute of Chemical Technology Curated by ChEMBL					Assay Description Inhibition of porcine aminopeptidase-N using Leu-pNA as substrate after 30 mins				Eur J Med Chem 106: 26-33 (2015) Article DOI: 10.1016/j.ejmech.2015.10.026 BindingDB Entry DOI: 10.7270/Q2FF3WCZ
					More data for this Ligand-Target Pair
Aminopeptidase N (Sus scrofa (Pig))	BDBM50499707 (CHEMBL3741904) Show SMILES OC1=CC(N(C(C1)c1cccnc1)c1ccccc1)c1cccnc1 |t:1| Show InChI InChI=1S/C21H19N3O/c25-19-12-20(16-6-4-10-22-14-16)24(18-8-2-1-3-9-18)21(13-19)17-7-5-11-23-15-17/h1-12,14-15,20-21,25H,13H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
CSIR-Indian Institute of Chemical Technology Curated by ChEMBL					Assay Description Inhibition of porcine aminopeptidase-N using Leu-pNA as substrate after 30 mins				Eur J Med Chem 106: 26-33 (2015) Article DOI: 10.1016/j.ejmech.2015.10.026 BindingDB Entry DOI: 10.7270/Q2FF3WCZ
					More data for this Ligand-Target Pair
Aminopeptidase N (Sus scrofa (Pig))	BDBM50499703 (CHEMBL3740862) Show SMILES CCOC(=O)C1C(N(C(CC1=O)c1ccccn1)c1ccccc1)c1ccccn1 Show InChI InChI=1S/C24H23N3O3/c1-2-30-24(29)22-21(28)16-20(18-12-6-8-14-25-18)27(17-10-4-3-5-11-17)23(22)19-13-7-9-15-26-19/h3-15,20,22-23H,2,16H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
CSIR-Indian Institute of Chemical Technology Curated by ChEMBL					Assay Description Inhibition of porcine aminopeptidase-N using Leu-pNA as substrate after 30 mins				Eur J Med Chem 106: 26-33 (2015) Article DOI: 10.1016/j.ejmech.2015.10.026 BindingDB Entry DOI: 10.7270/Q2FF3WCZ
					More data for this Ligand-Target Pair
Aminopeptidase N (Sus scrofa (Pig))	BDBM50499702 (CHEMBL3740370) Show SMILES CCOC(=O)C1C(N(C(CC1=O)c1cccnc1)c1ccccc1)c1cccnc1 Show InChI InChI=1S/C24H23N3O3/c1-2-30-24(29)22-21(28)14-20(17-8-6-12-25-15-17)27(19-10-4-3-5-11-19)23(22)18-9-7-13-26-16-18/h3-13,15-16,20,22-23H,2,14H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
CSIR-Indian Institute of Chemical Technology Curated by ChEMBL					Assay Description Inhibition of porcine aminopeptidase-N using Leu-pNA as substrate after 30 mins				Eur J Med Chem 106: 26-33 (2015) Article DOI: 10.1016/j.ejmech.2015.10.026 BindingDB Entry DOI: 10.7270/Q2FF3WCZ
					More data for this Ligand-Target Pair
Aminopeptidase N (Sus scrofa (Pig))	BDBM50499701 (CHEMBL3741701) Show SMILES CCOC(=O)C1=C(CC(N(C1c1ccccn1)c1ccccc1)c1ccccn1)Nc1ccccc1 |t:5| Show InChI InChI=1S/C30H28N4O2/c1-2-36-30(35)28-26(33-22-13-5-3-6-14-22)21-27(24-17-9-11-19-31-24)34(23-15-7-4-8-16-23)29(28)25-18-10-12-20-32-25/h3-20,27,29,33H,2,21H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
CSIR-Indian Institute of Chemical Technology Curated by ChEMBL					Assay Description Inhibition of porcine aminopeptidase-N using Leu-pNA as substrate after 30 mins				Eur J Med Chem 106: 26-33 (2015) Article DOI: 10.1016/j.ejmech.2015.10.026 BindingDB Entry DOI: 10.7270/Q2FF3WCZ
					More data for this Ligand-Target Pair
Aminopeptidase N (Sus scrofa (Pig))	BDBM50499710 (CHEMBL516021) Show SMILES CCOC(=O)C1=C(CC(N(C1c1cccnc1)c1ccccc1)c1cccnc1)Nc1ccccc1 |t:5| Show InChI InChI=1S/C30H28N4O2/c1-2-36-30(35)28-26(33-24-13-5-3-6-14-24)19-27(22-11-9-17-31-20-22)34(25-15-7-4-8-16-25)29(28)23-12-10-18-32-21-23/h3-18,20-21,27,29,33H,2,19H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
CSIR-Indian Institute of Chemical Technology Curated by ChEMBL					Assay Description Inhibition of porcine aminopeptidase-N using Leu-pNA as substrate after 30 mins				Eur J Med Chem 106: 26-33 (2015) Article DOI: 10.1016/j.ejmech.2015.10.026 BindingDB Entry DOI: 10.7270/Q2FF3WCZ
					More data for this Ligand-Target Pair
Aminopeptidase N (Sus scrofa (Pig))	BDBM50499713 (CHEMBL3741344) Show SMILES CCOC(=O)C1=C(CC(N(C1c1cccs1)c1ccccc1)c1ccc(Br)cc1)Nc1ccccc1 |t:5| Show InChI InChI=1S/C30H27BrN2O2S/c1-2-35-30(34)28-25(32-23-10-5-3-6-11-23)20-26(21-15-17-22(31)18-16-21)33(24-12-7-4-8-13-24)29(28)27-14-9-19-36-27/h3-19,26,29,32H,2,20H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
CSIR-Indian Institute of Chemical Technology Curated by ChEMBL					Assay Description Inhibition of porcine aminopeptidase-N using Leu-pNA as substrate after 30 mins				Eur J Med Chem 106: 26-33 (2015) Article DOI: 10.1016/j.ejmech.2015.10.026 BindingDB Entry DOI: 10.7270/Q2FF3WCZ
					More data for this Ligand-Target Pair
Aminopeptidase N (Sus scrofa (Pig))	BDBM50499712 (CHEMBL3741833) Show SMILES CCOC(=O)C1=C(CC(N(C1c1ccccn1)c1ccccc1)c1ccc(cc1)C#N)Nc1ccccc1 |t:5| Show InChI InChI=1S/C32H28N4O2/c1-2-38-32(37)30-28(35-25-11-5-3-6-12-25)21-29(24-18-16-23(22-33)17-19-24)36(26-13-7-4-8-14-26)31(30)27-15-9-10-20-34-27/h3-20,29,31,35H,2,21H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
CSIR-Indian Institute of Chemical Technology Curated by ChEMBL					Assay Description Inhibition of porcine aminopeptidase-N using Leu-pNA as substrate after 30 mins				Eur J Med Chem 106: 26-33 (2015) Article DOI: 10.1016/j.ejmech.2015.10.026 BindingDB Entry DOI: 10.7270/Q2FF3WCZ
					More data for this Ligand-Target Pair
Aminopeptidase N (Sus scrofa (Pig))	BDBM50499711 (CHEMBL3741419) Show SMILES CCOC(=O)C1=C(CC(N(C1c1cccnc1)c1ccccc1)c1ccc(Cl)cc1)Nc1ccccc1 |t:5| Show InChI InChI=1S/C31H28ClN3O2/c1-2-37-31(36)29-27(34-25-11-5-3-6-12-25)20-28(22-15-17-24(32)18-16-22)35(26-13-7-4-8-14-26)30(29)23-10-9-19-33-21-23/h3-19,21,28,30,34H,2,20H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
CSIR-Indian Institute of Chemical Technology Curated by ChEMBL					Assay Description Inhibition of porcine aminopeptidase-N using Leu-pNA as substrate after 30 mins				Eur J Med Chem 106: 26-33 (2015) Article DOI: 10.1016/j.ejmech.2015.10.026 BindingDB Entry DOI: 10.7270/Q2FF3WCZ
					More data for this Ligand-Target Pair
Methionine aminopeptidase 2 (Homo sapiens (Human))	BDBM17847 (CHEMBL327579 | pyridine-2-carboxylic acid inhibito...) Show SMILES CC(C)(C)OC(=O)Nc1cccnc1C(=O)Nc1nccs1 Show InChI InChI=1S/C14H16N4O3S/c1-14(2,3)21-13(20)17-9-5-4-6-15-10(9)11(19)18-12-16-7-8-22-12/h4-8H,1-3H3,(H,17,20)(H,16,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	>3.00E+5	n/a	n/a	n/a	n/a	7.5	22
Johns Hopkins University					Assay Description The MetAP reaction with Co2+ as a cofactor is coupled to a prolyl aminopeptidase (ProAP) using Met-Pro-p-nitroanilide as substrate. MetAP-catalyzed c...				Proc Natl Acad Sci U S A 103: 18148-53 (2006) Article DOI: 10.1073/pnas.0608389103 BindingDB Entry DOI: 10.7270/Q2RB72VK
					More data for this Ligand-Target Pair
Methionine aminopeptidase 2 (Homo sapiens (Human))	BDBM17850 (3-(3-phenylpropanamido)-N-(1,3-thiazol-2-yl)pyridi...) Show SMILES O=C(CCc1ccccc1)Nc1cccnc1C(=O)Nc1nccs1 Show InChI InChI=1S/C18H16N4O2S/c23-15(9-8-13-5-2-1-3-6-13)21-14-7-4-10-19-16(14)17(24)22-18-20-11-12-25-18/h1-7,10-12H,8-9H2,(H,21,23)(H,20,22,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	7.5	22
Johns Hopkins University					Assay Description The MetAP reaction with Co2+ as a cofactor is coupled to a prolyl aminopeptidase (ProAP) using Met-Pro-p-nitroanilide as substrate. MetAP-catalyzed c...				Proc Natl Acad Sci U S A 103: 18148-53 (2006) Article DOI: 10.1073/pnas.0608389103 BindingDB Entry DOI: 10.7270/Q2RB72VK
					More data for this Ligand-Target Pair
Methionine aminopeptidase 1 (Homo sapiens (Human))	BDBM17852 (3-octanamido-N-(1,3-thiazol-2-yl)pyridine-2-carbox...) Show SMILES CCCCCCCC(=O)Nc1cccnc1C(=O)Nc1nccs1 Show InChI InChI=1S/C17H22N4O2S/c1-2-3-4-5-6-9-14(22)20-13-8-7-10-18-15(13)16(23)21-17-19-11-12-24-17/h7-8,10-12H,2-6,9H2,1H3,(H,20,22)(H,19,21,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	7.5	22
Johns Hopkins University					Assay Description The MetAP reaction with Co2+ as a cofactor is coupled to a prolyl aminopeptidase (ProAP) using Met-Pro-p-nitroanilide as substrate. MetAP-catalyzed c...				Proc Natl Acad Sci U S A 103: 18148-53 (2006) Article DOI: 10.1073/pnas.0608389103 BindingDB Entry DOI: 10.7270/Q2RB72VK
					More data for this Ligand-Target Pair
Methionine aminopeptidase 2 (Homo sapiens (Human))	BDBM17852 (3-octanamido-N-(1,3-thiazol-2-yl)pyridine-2-carbox...) Show SMILES CCCCCCCC(=O)Nc1cccnc1C(=O)Nc1nccs1 Show InChI InChI=1S/C17H22N4O2S/c1-2-3-4-5-6-9-14(22)20-13-8-7-10-18-15(13)16(23)21-17-19-11-12-24-17/h7-8,10-12H,2-6,9H2,1H3,(H,20,22)(H,19,21,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	7.5	22
Johns Hopkins University					Assay Description The MetAP reaction with Co2+ as a cofactor is coupled to a prolyl aminopeptidase (ProAP) using Met-Pro-p-nitroanilide as substrate. MetAP-catalyzed c...				Proc Natl Acad Sci U S A 103: 18148-53 (2006) Article DOI: 10.1073/pnas.0608389103 BindingDB Entry DOI: 10.7270/Q2RB72VK
					More data for this Ligand-Target Pair
Methionine aminopeptidase 2 (Homo sapiens (Human))	BDBM17849 (3-(2,2-dimethylpropanamido)-N-(1,3-thiazol-2-yl)py...) Show SMILES CC(C)(C)C(=O)Nc1cccnc1C(=O)Nc1nccs1 Show InChI InChI=1S/C14H16N4O2S/c1-14(2,3)12(20)17-9-5-4-6-15-10(9)11(19)18-13-16-7-8-21-13/h4-8H,1-3H3,(H,17,20)(H,16,18,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	>5.00E+5	n/a	n/a	n/a	n/a	7.5	22
Johns Hopkins University					Assay Description The MetAP reaction with Co2+ as a cofactor is coupled to a prolyl aminopeptidase (ProAP) using Met-Pro-p-nitroanilide as substrate. MetAP-catalyzed c...				Proc Natl Acad Sci U S A 103: 18148-53 (2006) Article DOI: 10.1073/pnas.0608389103 BindingDB Entry DOI: 10.7270/Q2RB72VK
					More data for this Ligand-Target Pair
Methionine aminopeptidase 2 (Homo sapiens (Human))	BDBM17851 (3-[(E)-(2-methylpropylidene)amino]-N-(1,3-thiazol-...) Show SMILES CC(C)C=Nc1cccnc1C(=O)Nc1nccs1 |w:4.4| Show InChI InChI=1S/C13H14N4OS/c1-9(2)8-16-10-4-3-5-14-11(10)12(18)17-13-15-6-7-19-13/h3-9H,1-2H3,(H,15,17,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	7.5	22
Johns Hopkins University					Assay Description The MetAP reaction with Co2+ as a cofactor is coupled to a prolyl aminopeptidase (ProAP) using Met-Pro-p-nitroanilide as substrate. MetAP-catalyzed c...				Proc Natl Acad Sci U S A 103: 18148-53 (2006) Article DOI: 10.1073/pnas.0608389103 BindingDB Entry DOI: 10.7270/Q2RB72VK
					More data for this Ligand-Target Pair
Cholesterol side-chain cleavage enzyme, mitochondrial (Rattus norvegicus)	BDBM50507632 (CHEMBL4448381) Show SMILES C[C@@H](NC(=O)C(\O)=C\C(=O)c1oc2ccc(Br)cc2c1C)C(O)=O |r| Show InChI InChI=1S/C16H14BrNO6/c1-7-10-5-9(17)3-4-13(10)24-14(7)11(19)6-12(20)15(21)18-8(2)16(22)23/h3-6,8,20H,1-2H3,(H,18,21)(H,22,23)/b12-6-/t8-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.13E+6	n/a	n/a	n/a	n/a	n/a	n/a
TM Bhagalpur University Curated by ChEMBL					Assay Description Anti-biofilm activity against Enterococcus faecalis after 24 hrs by XTT assay				Eur J Med Chem 163: 67-82 (2019) Article DOI: 10.1016/j.ejmech.2018.11.053 BindingDB Entry DOI: 10.7270/Q21J9F24
					More data for this Ligand-Target Pair