Found 190 hits with Last Name = 'sanin' and Initial = 'a' Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Polyunsaturated fatty acid lipoxygenase ALOX15
(Homo sapiens (Human)) | BDBM50109578
(CHEMBL3604156)Show InChI InChI=1S/C10H5BrCl2FN3O/c11-7-8(16-17-9(7)13)10(18)15-6-2-1-4(14)3-5(6)12/h1-3H,(H,15,18)(H,16,17) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Uppsala University
Curated by ChEMBL
| Assay Description Inhibition of human 15-LOX-1 expressed in Sf9 cells assessed as reduction in conversion of arachidonic acid to 15-HETE pre-incubated 5 min before ara... |
Bioorg Med Chem Lett 25: 3024-9 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.004 BindingDB Entry DOI: 10.7270/Q2R21350 |
More data for this Ligand-Target Pair | |
Polyunsaturated fatty acid lipoxygenase ALOX15
(Homo sapiens (Human)) | BDBM50109729
(CHEMBL3604185)Show InChI InChI=1S/C10H4Cl3N3O/c11-4-1-2-5-6(3-4)17-10(14-5)8-7(12)9(13)16-15-8/h1-3H,(H,15,16) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Uppsala University
Curated by ChEMBL
| Assay Description Inhibition of human 15-LOX-1 expressed in Sf9 cells assessed as reduction in conversion of arachidonic acid to 15-HETE pre-incubated 5 min before ara... |
Bioorg Med Chem Lett 25: 3024-9 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.004 BindingDB Entry DOI: 10.7270/Q2R21350 |
More data for this Ligand-Target Pair | |
Polyunsaturated fatty acid lipoxygenase ALOX15
(Homo sapiens (Human)) | BDBM50109751
(CHEMBL3604184)Show InChI InChI=1S/C10H5Cl2N3O/c11-5-1-2-6-8(3-5)16-10(13-6)7-4-9(12)15-14-7/h1-4H,(H,14,15) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
Uppsala University
Curated by ChEMBL
| Assay Description Inhibition of human 15-LOX-1 expressed in Sf9 cells assessed as reduction in conversion of arachidonic acid to 15-HETE pre-incubated 5 min before ara... |
Bioorg Med Chem Lett 25: 3024-9 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.004 BindingDB Entry DOI: 10.7270/Q2R21350 |
More data for this Ligand-Target Pair | |
Polyunsaturated fatty acid lipoxygenase ALOX15
(Homo sapiens (Human)) | BDBM50109578
(CHEMBL3604156)Show InChI InChI=1S/C10H5BrCl2FN3O/c11-7-8(16-17-9(7)13)10(18)15-6-2-1-4(14)3-5(6)12/h1-3H,(H,15,18)(H,16,17) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 10 | n/a | n/a | n/a | n/a | n/a | n/a |
Uppsala University
Curated by ChEMBL
| Assay Description Inhibition of 15-LOX-1 in human L1236 cells assessed as reduction in conversion of arachidonic acid to 15-HETE pre-incubated 5 min before arachidonic... |
Bioorg Med Chem Lett 25: 3024-9 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.004 BindingDB Entry DOI: 10.7270/Q2R21350 |
More data for this Ligand-Target Pair | |
Polyunsaturated fatty acid lipoxygenase ALOX15
(Homo sapiens (Human)) | BDBM50109746
(CHEMBL3604180)Show InChI InChI=1S/C10H6ClN3O/c11-6-1-2-7-9(5-6)15-10(13-7)8-3-4-12-14-8/h1-5H,(H,12,14) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
Uppsala University
Curated by ChEMBL
| Assay Description Inhibition of 15-LOX-1 in human L1236 cells assessed as reduction in conversion of arachidonic acid to 15-HETE pre-incubated 5 min before arachidonic... |
Bioorg Med Chem Lett 25: 3024-9 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.004 BindingDB Entry DOI: 10.7270/Q2R21350 |
More data for this Ligand-Target Pair | |
Polyunsaturated fatty acid lipoxygenase ALOX15
(Homo sapiens (Human)) | BDBM50109814
(CHEMBL3604153)Show InChI InChI=1S/C10H5Cl3FN3O/c11-5-3-4(14)1-2-6(5)15-10(18)8-7(12)9(13)17-16-8/h1-3H,(H,15,18)(H,16,17) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a | n/a |
Uppsala University
Curated by ChEMBL
| Assay Description Inhibition of 15-LOX-1 in human L1236 cells assessed as reduction in conversion of arachidonic acid to 15-HETE pre-incubated 5 min before arachidonic... |
Bioorg Med Chem Lett 25: 3024-9 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.004 BindingDB Entry DOI: 10.7270/Q2R21350 |
More data for this Ligand-Target Pair | |
Polyunsaturated fatty acid lipoxygenase ALOX15
(Homo sapiens (Human)) | BDBM50105870
(CHEMBL3597768)Show SMILES Fc1ccc(NC(=O)c2ccn(n2)C(=S)Nc2ccc3OCOc3c2)c(Cl)c1 Show InChI InChI=1S/C18H12ClFN4O3S/c19-12-7-10(20)1-3-13(12)22-17(25)14-5-6-24(23-14)18(28)21-11-2-4-15-16(8-11)27-9-26-15/h1-8H,9H2,(H,21,28)(H,22,25) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a | n/a |
Uppsala University
Curated by ChEMBL
| Assay Description Inhibition of human 15-LOX-1 using arachidonic acid as substrate by cell based assay |
Bioorg Med Chem Lett 25: 3017-23 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.007 BindingDB Entry DOI: 10.7270/Q2F191G3 |
More data for this Ligand-Target Pair | |
Polyunsaturated fatty acid lipoxygenase ALOX15
(Homo sapiens (Human)) | BDBM50109746
(CHEMBL3604180)Show InChI InChI=1S/C10H6ClN3O/c11-6-1-2-7-9(5-6)15-10(13-7)8-3-4-12-14-8/h1-5H,(H,12,14) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
Uppsala University
Curated by ChEMBL
| Assay Description Inhibition of human 15-LOX-1 expressed in Sf9 cells assessed as reduction in conversion of arachidonic acid to 15-HETE pre-incubated 5 min before ara... |
Bioorg Med Chem Lett 25: 3024-9 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.004 BindingDB Entry DOI: 10.7270/Q2R21350 |
More data for this Ligand-Target Pair | |
Polyunsaturated fatty acid lipoxygenase ALOX15
(Homo sapiens (Human)) | BDBM50109813
(CHEMBL3604152)Show InChI InChI=1S/C10H6Cl2FN3O/c11-6-3-5(13)1-2-7(6)14-10(17)8-4-9(12)16-15-8/h1-4H,(H,14,17)(H,15,16) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 22 | n/a | n/a | n/a | n/a | n/a | n/a |
Uppsala University
Curated by ChEMBL
| Assay Description Inhibition of 15-LOX-1 in human L1236 cells assessed as reduction in conversion of arachidonic acid to 15-HETE pre-incubated 5 min before arachidonic... |
Bioorg Med Chem Lett 25: 3024-9 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.004 BindingDB Entry DOI: 10.7270/Q2R21350 |
More data for this Ligand-Target Pair | |
Polyunsaturated fatty acid lipoxygenase ALOX15
(Homo sapiens (Human)) | BDBM50109568
(CHEMBL3604132)Show InChI InChI=1S/C10H7ClFN3O/c11-7-5-6(12)1-2-8(7)14-10(16)9-3-4-13-15-9/h1-5H,(H,13,15)(H,14,16) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 24 | n/a | n/a | n/a | n/a | n/a | n/a |
Uppsala University
Curated by ChEMBL
| Assay Description Inhibition of 15-LOX-1 in human L1236 cells assessed as reduction in conversion of arachidonic acid to 15-HETE pre-incubated 5 min before arachidonic... |
Bioorg Med Chem Lett 25: 3024-9 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.004 BindingDB Entry DOI: 10.7270/Q2R21350 |
More data for this Ligand-Target Pair | |
Polyunsaturated fatty acid lipoxygenase ALOX15
(Homo sapiens (Human)) | BDBM50109539
(CHEMBL3604138)Show InChI InChI=1S/C9H7ClN4O/c10-6-1-2-8(11-5-6)13-9(15)7-3-4-12-14-7/h1-5H,(H,12,14)(H,11,13,15) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 26 | n/a | n/a | n/a | n/a | n/a | n/a |
Uppsala University
Curated by ChEMBL
| Assay Description Inhibition of human 15-LOX-1 expressed in Sf9 cells assessed as reduction in conversion of arachidonic acid to 15-HETE pre-incubated 5 min before ara... |
Bioorg Med Chem Lett 25: 3024-9 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.004 BindingDB Entry DOI: 10.7270/Q2R21350 |
More data for this Ligand-Target Pair | |
Polyunsaturated fatty acid lipoxygenase ALOX15
(Homo sapiens (Human)) | BDBM50109643
(CHEMBL3604158)Show InChI InChI=1S/C10H6ClFIN3O/c11-6-3-5(12)1-2-7(6)14-10(17)8-4-9(13)16-15-8/h1-4H,(H,14,17)(H,15,16) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 27 | n/a | n/a | n/a | n/a | n/a | n/a |
Uppsala University
Curated by ChEMBL
| Assay Description Inhibition of 15-LOX-1 in human L1236 cells assessed as reduction in conversion of arachidonic acid to 15-HETE pre-incubated 5 min before arachidonic... |
Bioorg Med Chem Lett 25: 3024-9 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.004 BindingDB Entry DOI: 10.7270/Q2R21350 |
More data for this Ligand-Target Pair | |
Polyunsaturated fatty acid lipoxygenase ALOX15
(Homo sapiens (Human)) | BDBM50109814
(CHEMBL3604153)Show InChI InChI=1S/C10H5Cl3FN3O/c11-5-3-4(14)1-2-6(5)15-10(18)8-7(12)9(13)17-16-8/h1-3H,(H,15,18)(H,16,17) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 32 | n/a | n/a | n/a | n/a | n/a | n/a |
Uppsala University
Curated by ChEMBL
| Assay Description Inhibition of human 15-LOX-1 expressed in Sf9 cells assessed as reduction in conversion of arachidonic acid to 15-HETE pre-incubated 5 min before ara... |
Bioorg Med Chem Lett 25: 3024-9 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.004 BindingDB Entry DOI: 10.7270/Q2R21350 |
More data for this Ligand-Target Pair | |
Polyunsaturated fatty acid lipoxygenase ALOX15
(Homo sapiens (Human)) | BDBM50109730
(CHEMBL3604151)Show InChI InChI=1S/C10H6Cl2FN3O/c11-6-3-5(13)1-2-8(6)15-10(17)9-7(12)4-14-16-9/h1-4H,(H,14,16)(H,15,17) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 33 | n/a | n/a | n/a | n/a | n/a | n/a |
Uppsala University
Curated by ChEMBL
| Assay Description Inhibition of 15-LOX-1 in human L1236 cells assessed as reduction in conversion of arachidonic acid to 15-HETE pre-incubated 5 min before arachidonic... |
Bioorg Med Chem Lett 25: 3024-9 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.004 BindingDB Entry DOI: 10.7270/Q2R21350 |
More data for this Ligand-Target Pair | |
Polyunsaturated fatty acid lipoxygenase ALOX15
(Homo sapiens (Human)) | BDBM50109729
(CHEMBL3604185)Show InChI InChI=1S/C10H4Cl3N3O/c11-4-1-2-5-6(3-4)17-10(14-5)8-7(12)9(13)16-15-8/h1-3H,(H,15,16) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 34 | n/a | n/a | n/a | n/a | n/a | n/a |
Uppsala University
Curated by ChEMBL
| Assay Description Inhibition of 15-LOX-1 in human L1236 cells assessed as reduction in conversion of arachidonic acid to 15-HETE pre-incubated 5 min before arachidonic... |
Bioorg Med Chem Lett 25: 3024-9 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.004 BindingDB Entry DOI: 10.7270/Q2R21350 |
More data for this Ligand-Target Pair | |
Polyunsaturated fatty acid lipoxygenase ALOX15
(Homo sapiens (Human)) | BDBM50109649
(CHEMBL3604162)Show SMILES Fc1ccc(NC(=O)c2n[nH]c(c2Cl)C(F)(F)F)c(Cl)c1 Show InChI InChI=1S/C11H5Cl2F4N3O/c12-5-3-4(14)1-2-6(5)18-10(21)8-7(13)9(20-19-8)11(15,16)17/h1-3H,(H,18,21)(H,19,20) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 37 | n/a | n/a | n/a | n/a | n/a | n/a |
Uppsala University
Curated by ChEMBL
| Assay Description Inhibition of 15-LOX-1 in human L1236 cells assessed as reduction in conversion of arachidonic acid to 15-HETE pre-incubated 5 min before arachidonic... |
Bioorg Med Chem Lett 25: 3024-9 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.004 BindingDB Entry DOI: 10.7270/Q2R21350 |
More data for this Ligand-Target Pair | |
Polyunsaturated fatty acid lipoxygenase ALOX15
(Homo sapiens (Human)) | BDBM50109752
(CHEMBL3604164)Show InChI InChI=1S/C11H6Cl2F3N3O/c12-5-3-4(14)1-2-6(5)17-11(20)9-7(13)8(10(15)16)18-19-9/h1-3,10H,(H,17,20)(H,18,19) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 39 | n/a | n/a | n/a | n/a | n/a | n/a |
Uppsala University
Curated by ChEMBL
| Assay Description Inhibition of 15-LOX-1 in human L1236 cells assessed as reduction in conversion of arachidonic acid to 15-HETE pre-incubated 5 min before arachidonic... |
Bioorg Med Chem Lett 25: 3024-9 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.004 BindingDB Entry DOI: 10.7270/Q2R21350 |
More data for this Ligand-Target Pair | |
Polyunsaturated fatty acid lipoxygenase ALOX15
(Homo sapiens (Human)) | BDBM50109577
(CHEMBL3604155)Show InChI InChI=1S/C10H6BrClFN3O/c11-6-4-14-16-9(6)10(17)15-8-2-1-5(13)3-7(8)12/h1-4H,(H,14,16)(H,15,17) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 39 | n/a | n/a | n/a | n/a | n/a | n/a |
Uppsala University
Curated by ChEMBL
| Assay Description Inhibition of 15-LOX-1 in human L1236 cells assessed as reduction in conversion of arachidonic acid to 15-HETE pre-incubated 5 min before arachidonic... |
Bioorg Med Chem Lett 25: 3024-9 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.004 BindingDB Entry DOI: 10.7270/Q2R21350 |
More data for this Ligand-Target Pair | |
Polyunsaturated fatty acid lipoxygenase ALOX15
(Homo sapiens (Human)) | BDBM50109736
(CHEMBL3604149)Show InChI InChI=1S/C14H15ClFN3O/c1-14(2,3)12-7-11(18-19-12)13(20)17-10-5-4-8(16)6-9(10)15/h4-7H,1-3H3,(H,17,20)(H,18,19) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
| Article PubMed
| n/a | n/a | 42 | n/a | n/a | n/a | n/a | n/a | n/a |
Uppsala University
Curated by ChEMBL
| Assay Description Inhibition of 15-LOX-1 in human L1236 cells assessed as reduction in conversion of arachidonic acid to 15-HETE pre-incubated 5 min before arachidonic... |
Bioorg Med Chem Lett 25: 3024-9 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.004 BindingDB Entry DOI: 10.7270/Q2R21350 |
More data for this Ligand-Target Pair | |
Polyunsaturated fatty acid lipoxygenase ALOX15
(Homo sapiens (Human)) | BDBM50109576
(CHEMBL3604154)Show InChI InChI=1S/C10H6ClF2N3O/c11-6-3-5(12)1-2-8(6)15-10(17)9-7(13)4-14-16-9/h1-4H,(H,14,16)(H,15,17) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 42 | n/a | n/a | n/a | n/a | n/a | n/a |
Uppsala University
Curated by ChEMBL
| Assay Description Inhibition of 15-LOX-1 in human L1236 cells assessed as reduction in conversion of arachidonic acid to 15-HETE pre-incubated 5 min before arachidonic... |
Bioorg Med Chem Lett 25: 3024-9 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.004 BindingDB Entry DOI: 10.7270/Q2R21350 |
More data for this Ligand-Target Pair | |
Polyunsaturated fatty acid lipoxygenase ALOX15
(Homo sapiens (Human)) | BDBM50109539
(CHEMBL3604138)Show InChI InChI=1S/C9H7ClN4O/c10-6-1-2-8(11-5-6)13-9(15)7-3-4-12-14-7/h1-5H,(H,12,14)(H,11,13,15) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 43 | n/a | n/a | n/a | n/a | n/a | n/a |
Uppsala University
Curated by ChEMBL
| Assay Description Inhibition of 15-LOX-1 in human L1236 cells assessed as reduction in conversion of arachidonic acid to 15-HETE pre-incubated 5 min before arachidonic... |
Bioorg Med Chem Lett 25: 3024-9 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.004 BindingDB Entry DOI: 10.7270/Q2R21350 |
More data for this Ligand-Target Pair | |
Polyunsaturated fatty acid lipoxygenase ALOX15
(Homo sapiens (Human)) | BDBM50109707
(CHEMBL445420)Show InChI InChI=1S/C10H9N3O/c14-10(9-6-7-11-13-9)12-8-4-2-1-3-5-8/h1-7H,(H,11,13)(H,12,14) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE PC cid PC sid PDB UniChem
Similars
| Article PubMed
| n/a | n/a | 47 | n/a | n/a | n/a | n/a | n/a | n/a |
Uppsala University
Curated by ChEMBL
| Assay Description Inhibition of 15-LOX-1 in human L1236 cells assessed as reduction in conversion of arachidonic acid to 15-HETE pre-incubated 5 min before arachidonic... |
Bioorg Med Chem Lett 25: 3024-9 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.004 BindingDB Entry DOI: 10.7270/Q2R21350 |
More data for this Ligand-Target Pair | |
Polyunsaturated fatty acid lipoxygenase ALOX15
(Homo sapiens (Human)) | BDBM50105866
(CHEMBL3597764)Show SMILES Fc1ccc(NC(=O)c2ccn(n2)C(=O)Nc2ccc3OCOc3c2)c(Cl)c1 Show InChI InChI=1S/C18H12ClFN4O4/c19-12-7-10(20)1-3-13(12)22-17(25)14-5-6-24(23-14)18(26)21-11-2-4-15-16(8-11)28-9-27-15/h1-8H,9H2,(H,21,26)(H,22,25) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 47 | n/a | n/a | n/a | n/a | n/a | n/a |
Uppsala University
Curated by ChEMBL
| Assay Description Inhibition of human 15-LOX-1 using arachidonic acid as substrate by cell based assay |
Bioorg Med Chem Lett 25: 3017-23 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.007 BindingDB Entry DOI: 10.7270/Q2F191G3 |
More data for this Ligand-Target Pair | |
Polyunsaturated fatty acid lipoxygenase ALOX15
(Homo sapiens (Human)) | BDBM50109702
(CHEMBL3604174)Show InChI InChI=1S/C9H6Cl2N4O/c10-5-1-2-7(6(11)3-5)13-9(16)8-4-12-15-14-8/h1-4H,(H,13,16)(H,12,14,15) | PDB
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| Article PubMed
| n/a | n/a | 56 | n/a | n/a | n/a | n/a | n/a | n/a |
Uppsala University
Curated by ChEMBL
| Assay Description Inhibition of 15-LOX-1 in human L1236 cells assessed as reduction in conversion of arachidonic acid to 15-HETE pre-incubated 5 min before arachidonic... |
Bioorg Med Chem Lett 25: 3024-9 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.004 BindingDB Entry DOI: 10.7270/Q2R21350 |
More data for this Ligand-Target Pair | |
Polyunsaturated fatty acid lipoxygenase ALOX15
(Homo sapiens (Human)) | BDBM50109740
(CHEMBL3604173)Show InChI InChI=1S/C9H6ClFN4O/c10-6-3-5(11)1-2-7(6)13-9(16)8-4-12-15-14-8/h1-4H,(H,13,16)(H,12,14,15) | PDB
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CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 68 | n/a | n/a | n/a | n/a | n/a | n/a |
Uppsala University
Curated by ChEMBL
| Assay Description Inhibition of 15-LOX-1 in human L1236 cells assessed as reduction in conversion of arachidonic acid to 15-HETE pre-incubated 5 min before arachidonic... |
Bioorg Med Chem Lett 25: 3024-9 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.004 BindingDB Entry DOI: 10.7270/Q2R21350 |
More data for this Ligand-Target Pair | |
Polyunsaturated fatty acid lipoxygenase ALOX15
(Homo sapiens (Human)) | BDBM50109731
(CHEMBL3604166)Show InChI InChI=1S/C10H8ClFN4O/c11-6-3-5(12)1-2-8(6)15-10(17)9-7(13)4-14-16-9/h1-4H,13H2,(H,14,16)(H,15,17) | PDB
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B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 69 | n/a | n/a | n/a | n/a | n/a | n/a |
Uppsala University
Curated by ChEMBL
| Assay Description Inhibition of 15-LOX-1 in human L1236 cells assessed as reduction in conversion of arachidonic acid to 15-HETE pre-incubated 5 min before arachidonic... |
Bioorg Med Chem Lett 25: 3024-9 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.004 BindingDB Entry DOI: 10.7270/Q2R21350 |
More data for this Ligand-Target Pair | |
Polyunsaturated fatty acid lipoxygenase ALOX15
(Homo sapiens (Human)) | BDBM50109813
(CHEMBL3604152)Show InChI InChI=1S/C10H6Cl2FN3O/c11-6-3-5(13)1-2-7(6)14-10(17)8-4-9(12)16-15-8/h1-4H,(H,14,17)(H,15,16) | PDB
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Patents
Similars
| Article PubMed
| n/a | n/a | 71 | n/a | n/a | n/a | n/a | n/a | n/a |
Uppsala University
Curated by ChEMBL
| Assay Description Inhibition of human 15-LOX-1 expressed in Sf9 cells assessed as reduction in conversion of arachidonic acid to 15-HETE pre-incubated 5 min before ara... |
Bioorg Med Chem Lett 25: 3024-9 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.004 BindingDB Entry DOI: 10.7270/Q2R21350 |
More data for this Ligand-Target Pair | |
Polyunsaturated fatty acid lipoxygenase ALOX15
(Sus scrofa) | BDBM50109702
(CHEMBL3604174)Show InChI InChI=1S/C9H6Cl2N4O/c10-5-1-2-7(6(11)3-5)13-9(16)8-4-12-15-14-8/h1-4H,(H,13,16)(H,12,14,15) | PDB
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| Article PubMed
| n/a | n/a | 78 | n/a | n/a | n/a | n/a | n/a | n/a |
Uppsala University
Curated by ChEMBL
| Assay Description Inhibition of pig 15-LOX-1 expressed in Sf9 cells assessed as reduction in conversion of arachidonic acid to 15-HETE pre-incubated 5 min before arach... |
Bioorg Med Chem Lett 25: 3024-9 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.004 BindingDB Entry DOI: 10.7270/Q2R21350 |
More data for this Ligand-Target Pair | |
Polyunsaturated fatty acid lipoxygenase ALOX15
(Homo sapiens (Human)) | BDBM50109741
(CHEMBL3604175)Show InChI InChI=1S/C9H6Cl2N4O/c10-5-1-2-6(11)7(3-5)13-9(16)8-4-12-15-14-8/h1-4H,(H,13,16)(H,12,14,15) | PDB
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CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 79 | n/a | n/a | n/a | n/a | n/a | n/a |
Uppsala University
Curated by ChEMBL
| Assay Description Inhibition of 15-LOX-1 in human L1236 cells assessed as reduction in conversion of arachidonic acid to 15-HETE pre-incubated 5 min before arachidonic... |
Bioorg Med Chem Lett 25: 3024-9 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.004 BindingDB Entry DOI: 10.7270/Q2R21350 |
More data for this Ligand-Target Pair | |
Polyunsaturated fatty acid lipoxygenase ALOX15
(Homo sapiens (Human)) | BDBM50109568
(CHEMBL3604132)Show InChI InChI=1S/C10H7ClFN3O/c11-7-5-6(12)1-2-8(7)14-10(16)9-3-4-13-15-9/h1-5H,(H,13,15)(H,14,16) | PDB
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| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 81 | n/a | n/a | n/a | n/a | n/a | n/a |
Uppsala University
Curated by ChEMBL
| Assay Description Inhibition of human 15-LOX-1 expressed in Sf9 cells assessed as reduction in conversion of arachidonic acid to 15-HETE pre-incubated 5 min before ara... |
Bioorg Med Chem Lett 25: 3024-9 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.004 BindingDB Entry DOI: 10.7270/Q2R21350 |
More data for this Ligand-Target Pair | |
Polyunsaturated fatty acid lipoxygenase ALOX15
(Homo sapiens (Human)) | BDBM50109730
(CHEMBL3604151)Show InChI InChI=1S/C10H6Cl2FN3O/c11-6-3-5(13)1-2-8(6)15-10(17)9-7(12)4-14-16-9/h1-4H,(H,14,16)(H,15,17) | PDB
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| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 85 | n/a | n/a | n/a | n/a | n/a | n/a |
Uppsala University
Curated by ChEMBL
| Assay Description Inhibition of human 15-LOX-1 expressed in Sf9 cells assessed as reduction in conversion of arachidonic acid to 15-HETE pre-incubated 5 min before ara... |
Bioorg Med Chem Lett 25: 3024-9 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.004 BindingDB Entry DOI: 10.7270/Q2R21350 |
More data for this Ligand-Target Pair | |
Polyunsaturated fatty acid lipoxygenase ALOX15
(Homo sapiens (Human)) | BDBM50105864
(CHEMBL3597775)Show InChI InChI=1S/C18H22ClFN4O2/c1-3-4-5-6-9-21-18(26)24-12(2)10-16(23-24)17(25)22-15-8-7-13(20)11-14(15)19/h7-8,10-11H,3-6,9H2,1-2H3,(H,21,26)(H,22,25) | PDB
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| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 85 | n/a | n/a | n/a | n/a | n/a | n/a |
Uppsala University
Curated by ChEMBL
| Assay Description Inhibition of human 15-LOX-1 using arachidonic acid as substrate by cell based assay |
Bioorg Med Chem Lett 25: 3017-23 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.007 BindingDB Entry DOI: 10.7270/Q2F191G3 |
More data for this Ligand-Target Pair | |
Polyunsaturated fatty acid lipoxygenase ALOX15
(Homo sapiens (Human)) | BDBM50109562
(CHEMBL3604141)Show InChI InChI=1S/C13H10N4O/c18-13(12-5-6-15-17-12)16-10-7-9-3-1-2-4-11(9)14-8-10/h1-8H,(H,15,17)(H,16,18) | PDB
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| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 92 | n/a | n/a | n/a | n/a | n/a | n/a |
Uppsala University
Curated by ChEMBL
| Assay Description Inhibition of 15-LOX-1 in human L1236 cells assessed as reduction in conversion of arachidonic acid to 15-HETE pre-incubated 5 min before arachidonic... |
Bioorg Med Chem Lett 25: 3024-9 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.004 BindingDB Entry DOI: 10.7270/Q2R21350 |
More data for this Ligand-Target Pair | |
Polyunsaturated fatty acid lipoxygenase ALOX15
(Homo sapiens (Human)) | BDBM50109570
(CHEMBL3604134)Show InChI InChI=1S/C11H7F4N3O/c12-6-1-2-8(7(5-6)11(13,14)15)17-10(19)9-3-4-16-18-9/h1-5H,(H,16,18)(H,17,19) | PDB
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| CHEMBL MMDB PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 94 | n/a | n/a | n/a | n/a | n/a | n/a |
Uppsala University
Curated by ChEMBL
| Assay Description Inhibition of 15-LOX-1 in human L1236 cells assessed as reduction in conversion of arachidonic acid to 15-HETE pre-incubated 5 min before arachidonic... |
Bioorg Med Chem Lett 25: 3024-9 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.004 BindingDB Entry DOI: 10.7270/Q2R21350 |
More data for this Ligand-Target Pair | |
Polyunsaturated fatty acid lipoxygenase ALOX15
(Homo sapiens (Human)) | BDBM50109737
(CHEMBL3604170)Show InChI InChI=1S/C9H8N4O/c14-9(8-6-10-13-12-8)11-7-4-2-1-3-5-7/h1-6H,(H,11,14)(H,10,12,13) | PDB
Reactome pathway KEGG
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B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 97 | n/a | n/a | n/a | n/a | n/a | n/a |
Uppsala University
Curated by ChEMBL
| Assay Description Inhibition of 15-LOX-1 in human L1236 cells assessed as reduction in conversion of arachidonic acid to 15-HETE pre-incubated 5 min before arachidonic... |
Bioorg Med Chem Lett 25: 3024-9 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.004 BindingDB Entry DOI: 10.7270/Q2R21350 |
More data for this Ligand-Target Pair | |
Polyunsaturated fatty acid lipoxygenase ALOX15
(Homo sapiens (Human)) | BDBM50109702
(CHEMBL3604174)Show InChI InChI=1S/C9H6Cl2N4O/c10-5-1-2-7(6(11)3-5)13-9(16)8-4-12-15-14-8/h1-4H,(H,13,16)(H,12,14,15) | PDB
Reactome pathway KEGG
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B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 99 | n/a | n/a | n/a | n/a | n/a | n/a |
Uppsala University
Curated by ChEMBL
| Assay Description Inhibition of human 15-LOX-1 expressed in Sf9 cells assessed as reduction in conversion of arachidonic acid to 15-HETE pre-incubated 5 min before ara... |
Bioorg Med Chem Lett 25: 3024-9 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.004 BindingDB Entry DOI: 10.7270/Q2R21350 |
More data for this Ligand-Target Pair | |
Polyunsaturated fatty acid lipoxygenase ALOX15
(Homo sapiens (Human)) | BDBM50105866
(CHEMBL3597764)Show SMILES Fc1ccc(NC(=O)c2ccn(n2)C(=O)Nc2ccc3OCOc3c2)c(Cl)c1 Show InChI InChI=1S/C18H12ClFN4O4/c19-12-7-10(20)1-3-13(12)22-17(25)14-5-6-24(23-14)18(26)21-11-2-4-15-16(8-11)28-9-27-15/h1-8H,9H2,(H,21,26)(H,22,25) | PDB
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UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 109 | n/a | n/a | n/a | n/a | n/a | n/a |
Uppsala University
Curated by ChEMBL
| Assay Description Inhibition of human 15-LOX-1 using arachidonic acid as substrate |
Bioorg Med Chem Lett 25: 3017-23 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.007 BindingDB Entry DOI: 10.7270/Q2F191G3 |
More data for this Ligand-Target Pair | |
Polyunsaturated fatty acid lipoxygenase ALOX15
(Homo sapiens (Human)) | BDBM50109646
(CHEMBL3604160)Show InChI InChI=1S/C11H6ClF4N3O/c12-6-3-5(13)1-2-7(6)17-10(20)8-4-9(19-18-8)11(14,15)16/h1-4H,(H,17,20)(H,18,19) | PDB
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B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 112 | n/a | n/a | n/a | n/a | n/a | n/a |
Uppsala University
Curated by ChEMBL
| Assay Description Inhibition of 15-LOX-1 in human L1236 cells assessed as reduction in conversion of arachidonic acid to 15-HETE pre-incubated 5 min before arachidonic... |
Bioorg Med Chem Lett 25: 3024-9 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.004 BindingDB Entry DOI: 10.7270/Q2R21350 |
More data for this Ligand-Target Pair | |
Polyunsaturated fatty acid lipoxygenase ALOX15
(Homo sapiens (Human)) | BDBM50109645
(CHEMBL3604159)Show InChI InChI=1S/C11H6ClF4N3O/c12-7-3-5(13)1-2-8(7)18-10(20)9-6(4-17-19-9)11(14,15)16/h1-4H,(H,17,19)(H,18,20) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 117 | n/a | n/a | n/a | n/a | n/a | n/a |
Uppsala University
Curated by ChEMBL
| Assay Description Inhibition of 15-LOX-1 in human L1236 cells assessed as reduction in conversion of arachidonic acid to 15-HETE pre-incubated 5 min before arachidonic... |
Bioorg Med Chem Lett 25: 3024-9 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.004 BindingDB Entry DOI: 10.7270/Q2R21350 |
More data for this Ligand-Target Pair | |
Polyunsaturated fatty acid lipoxygenase ALOX15
(Homo sapiens (Human)) | BDBM50109815
(CHEMBL3604137)Show InChI InChI=1S/C9H7FN4O/c10-6-1-2-8(11-5-6)13-9(15)7-3-4-12-14-7/h1-5H,(H,12,14)(H,11,13,15) | PDB
Reactome pathway KEGG
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B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 118 | n/a | n/a | n/a | n/a | n/a | n/a |
Uppsala University
Curated by ChEMBL
| Assay Description Inhibition of 15-LOX-1 in human L1236 cells assessed as reduction in conversion of arachidonic acid to 15-HETE pre-incubated 5 min before arachidonic... |
Bioorg Med Chem Lett 25: 3024-9 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.004 BindingDB Entry DOI: 10.7270/Q2R21350 |
More data for this Ligand-Target Pair | |
Polyunsaturated fatty acid lipoxygenase ALOX15
(Homo sapiens (Human)) | BDBM50109747
(CHEMBL3604181)Show InChI InChI=1S/C10H6ClN3O/c11-6-1-2-9-8(5-6)13-10(15-9)7-3-4-12-14-7/h1-5H,(H,12,14) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 124 | n/a | n/a | n/a | n/a | n/a | n/a |
Uppsala University
Curated by ChEMBL
| Assay Description Inhibition of 15-LOX-1 in human L1236 cells assessed as reduction in conversion of arachidonic acid to 15-HETE pre-incubated 5 min before arachidonic... |
Bioorg Med Chem Lett 25: 3024-9 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.004 BindingDB Entry DOI: 10.7270/Q2R21350 |
More data for this Ligand-Target Pair | |
Polyunsaturated fatty acid lipoxygenase ALOX15
(Homo sapiens (Human)) | BDBM50105867
(CHEMBL3597765)Show InChI InChI=1S/C16H18ClFN4O2/c1-2-3-4-8-19-16(24)22-9-7-14(21-22)15(23)20-13-6-5-11(18)10-12(13)17/h5-7,9-10H,2-4,8H2,1H3,(H,19,24)(H,20,23) | PDB
Reactome pathway KEGG
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B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 130 | n/a | n/a | n/a | n/a | n/a | n/a |
Uppsala University
Curated by ChEMBL
| Assay Description Inhibition of human 15-LOX-1 using arachidonic acid as substrate |
Bioorg Med Chem Lett 25: 3017-23 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.007 BindingDB Entry DOI: 10.7270/Q2F191G3 |
More data for this Ligand-Target Pair | |
Polyunsaturated fatty acid lipoxygenase ALOX15
(Homo sapiens (Human)) | BDBM50109561
(CHEMBL3604139)Show InChI InChI=1S/C7H5ClN4OS/c8-5-3-9-7(14-5)11-6(13)4-1-2-10-12-4/h1-3H,(H,10,12)(H,9,11,13) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 130 | n/a | n/a | n/a | n/a | n/a | n/a |
Uppsala University
Curated by ChEMBL
| Assay Description Inhibition of 15-LOX-1 in human L1236 cells assessed as reduction in conversion of arachidonic acid to 15-HETE pre-incubated 5 min before arachidonic... |
Bioorg Med Chem Lett 25: 3024-9 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.004 BindingDB Entry DOI: 10.7270/Q2R21350 |
More data for this Ligand-Target Pair | |
Polyunsaturated fatty acid lipoxygenase ALOX15
(Homo sapiens (Human)) | BDBM50109751
(CHEMBL3604184)Show InChI InChI=1S/C10H5Cl2N3O/c11-5-1-2-6-8(3-5)16-10(13-6)7-4-9(12)15-14-7/h1-4H,(H,14,15) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 131 | n/a | n/a | n/a | n/a | n/a | n/a |
Uppsala University
Curated by ChEMBL
| Assay Description Inhibition of 15-LOX-1 in human L1236 cells assessed as reduction in conversion of arachidonic acid to 15-HETE pre-incubated 5 min before arachidonic... |
Bioorg Med Chem Lett 25: 3024-9 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.004 BindingDB Entry DOI: 10.7270/Q2R21350 |
More data for this Ligand-Target Pair | |
Polyunsaturated fatty acid lipoxygenase ALOX15
(Homo sapiens (Human)) | BDBM50105868
(CHEMBL3597766)Show SMILES CCOC(=O)CCCCCNC(=O)n1ccc(n1)C(=O)Nc1ccc(F)cc1Cl Show InChI InChI=1S/C19H22ClFN4O4/c1-2-29-17(26)6-4-3-5-10-22-19(28)25-11-9-16(24-25)18(27)23-15-8-7-13(21)12-14(15)20/h7-9,11-12H,2-6,10H2,1H3,(H,22,28)(H,23,27) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 141 | n/a | n/a | n/a | n/a | n/a | n/a |
Uppsala University
Curated by ChEMBL
| Assay Description Inhibition of human 15-LOX-1 using arachidonic acid as substrate by cell based assay |
Bioorg Med Chem Lett 25: 3017-23 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.007 BindingDB Entry DOI: 10.7270/Q2F191G3 |
More data for this Ligand-Target Pair | |
Polyunsaturated fatty acid lipoxygenase ALOX15
(Homo sapiens (Human)) | BDBM50109643
(CHEMBL3604158)Show InChI InChI=1S/C10H6ClFIN3O/c11-6-3-5(12)1-2-7(6)14-10(17)8-4-9(13)16-15-8/h1-4H,(H,14,17)(H,15,16) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 150 | n/a | n/a | n/a | n/a | n/a | n/a |
Uppsala University
Curated by ChEMBL
| Assay Description Inhibition of human 15-LOX-1 expressed in Sf9 cells assessed as reduction in conversion of arachidonic acid to 15-HETE pre-incubated 5 min before ara... |
Bioorg Med Chem Lett 25: 3024-9 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.004 BindingDB Entry DOI: 10.7270/Q2R21350 |
More data for this Ligand-Target Pair | |
Polyunsaturated fatty acid lipoxygenase ALOX15
(Homo sapiens (Human)) | BDBM50109570
(CHEMBL3604134)Show InChI InChI=1S/C11H7F4N3O/c12-6-1-2-8(7(5-6)11(13,14)15)17-10(19)9-3-4-16-18-9/h1-5H,(H,16,18)(H,17,19) | PDB
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UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL MMDB PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 168 | n/a | n/a | n/a | n/a | n/a | n/a |
Uppsala University
Curated by ChEMBL
| Assay Description Inhibition of human 15-LOX-1 expressed in Sf9 cells assessed as reduction in conversion of arachidonic acid to 15-HETE pre-incubated 5 min before ara... |
Bioorg Med Chem Lett 25: 3024-9 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.004 BindingDB Entry DOI: 10.7270/Q2R21350 |
More data for this Ligand-Target Pair | |
Polyunsaturated fatty acid lipoxygenase ALOX15
(Homo sapiens (Human)) | BDBM50109567
(CHEMBL3604131)Show InChI InChI=1S/C10H7Cl2N3O/c11-7-2-1-6(5-8(7)12)14-10(16)9-3-4-13-15-9/h1-5H,(H,13,15)(H,14,16) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 180 | n/a | n/a | n/a | n/a | n/a | n/a |
Uppsala University
Curated by ChEMBL
| Assay Description Inhibition of human 15-LOX-1 expressed in Sf9 cells assessed as reduction in conversion of arachidonic acid to 15-HETE pre-incubated 5 min before ara... |
Bioorg Med Chem Lett 25: 3024-9 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.004 BindingDB Entry DOI: 10.7270/Q2R21350 |
More data for this Ligand-Target Pair | |
Polyunsaturated fatty acid lipoxygenase ALOX15
(Homo sapiens (Human)) | BDBM50109562
(CHEMBL3604141)Show InChI InChI=1S/C13H10N4O/c18-13(12-5-6-15-17-12)16-10-7-9-3-1-2-4-11(9)14-8-10/h1-8H,(H,15,17)(H,16,18) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 180 | n/a | n/a | n/a | n/a | n/a | n/a |
Uppsala University
Curated by ChEMBL
| Assay Description Inhibition of human 15-LOX-1 expressed in Sf9 cells assessed as reduction in conversion of arachidonic acid to 15-HETE pre-incubated 5 min before ara... |
Bioorg Med Chem Lett 25: 3024-9 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.004 BindingDB Entry DOI: 10.7270/Q2R21350 |
More data for this Ligand-Target Pair | |
Polyunsaturated fatty acid lipoxygenase ALOX15
(Homo sapiens (Human)) | BDBM50109733
(CHEMBL3604146)Show InChI InChI=1S/C11H9ClFN3O/c1-6-5-14-16-10(6)11(17)15-9-3-2-7(13)4-8(9)12/h2-5H,1H3,(H,14,16)(H,15,17) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 183 | n/a | n/a | n/a | n/a | n/a | n/a |
Uppsala University
Curated by ChEMBL
| Assay Description Inhibition of 15-LOX-1 in human L1236 cells assessed as reduction in conversion of arachidonic acid to 15-HETE pre-incubated 5 min before arachidonic... |
Bioorg Med Chem Lett 25: 3024-9 (2015)
Article DOI: 10.1016/j.bmcl.2015.05.004 BindingDB Entry DOI: 10.7270/Q2R21350 |
More data for this Ligand-Target Pair | |