Compile Data Set for Download or QSAR

Found 214 hits with Last Name = 'portevin' and Initial = 'b'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50094539 (3,5-Bis-(4-fluoro-phenyl)-4-aza-tricyclo[5.2.1.0*2...) Show SMILES Fc1ccc(cc1)-c1[nH]c(c2C3CCC(C3)c12)-c1ccc(F)cc1 Show InChI InChI=1S/C21H17F2N/c22-16-7-3-12(4-8-16)20-18-14-1-2-15(11-14)19(18)21(24-20)13-5-9-17(23)10-6-13/h3-10,14-15,24H,1-2,11H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	0.0800	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherche Servier Curated by ChEMBL					Assay Description Tested in vitro for inhibition against Prostaglandin G/H synthase 2 in human blood (95% confidence limits)				J Med Chem 43: 4582-93 (2001) BindingDB Entry DOI: 10.7270/Q23B60T1
					More data for this Ligand-Target Pair
Prolyl endopeptidase (Rattus norvegicus)	BDBM50051495 ((S)-2-[(S)-2-(2-Hydroxy-acetyl)-pyrrolidine-1-carb...) Show SMILES OCC(=O)[C@@H]1CCCN1C(=O)[C@@H]1CCCN1C(=O)NCc1ccccc1 Show InChI InChI=1S/C19H25N3O4/c23-13-17(24)15-8-4-10-21(15)18(25)16-9-5-11-22(16)19(26)20-12-14-6-2-1-3-7-14/h1-3,6-7,15-16,23H,4-5,8-13H2,(H,20,26)/t15-,16-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.100	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherche Servier Curated by ChEMBL					Assay Description Inhibitory activity of the compound was evaluated against Post-proline cleaving enzyme from rat brain				J Med Chem 39: 2379-91 (1996) Article DOI: 10.1021/jm950858c BindingDB Entry DOI: 10.7270/Q2RF5T4J
					More data for this Ligand-Target Pair
Neutrophil elastase (Homo sapiens (Human))	BDBM50058495 (3-{2-[2-(Thiophene-2-carbonylsulfanyl)-propionylam...) Show SMILES CC(SC(=O)c1cccs1)C(=O)NCC(=O)N1CSCC1C(O)=O Show InChI InChI=1S/C14H16N2O5S3/c1-8(24-14(21)10-3-2-4-23-10)12(18)15-5-11(17)16-7-22-6-9(16)13(19)20/h2-4,8-9H,5-7H2,1H3,(H,15,18)(H,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.100	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherche Servier Curated by ChEMBL					Assay Description Inhibitory concentration against Human Leukocyte Elastase from human sputum				J Med Chem 40: 1906-18 (1997) Article DOI: 10.1021/jm960772z BindingDB Entry DOI: 10.7270/Q2MS3RW1
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Homo sapiens (Human))	BDBM50094551 (3,5-Bis-(4-fluoro-phenyl)-4-aza-tricyclo[5.2.2.0*2...) Show SMILES Fc1ccc(cc1)-c1[nH]c(c2C3CCC(CC3)c12)-c1ccc(F)cc1 |(21.01,-36.41,;22.48,-35.94,;22.8,-34.43,;24.27,-33.96,;25.41,-35,;25.09,-36.5,;23.63,-36.98,;26.88,-34.53,;28.12,-35.45,;29.38,-34.55,;28.9,-33.08,;29.67,-31.77,;28.93,-30.43,;27.39,-30.42,;26.61,-31.74,;27.93,-30.96,;28.33,-32.53,;27.36,-33.07,;30.84,-35.03,;31.15,-36.54,;32.61,-37.02,;33.76,-36,;35.23,-36.48,;33.44,-34.48,;31.98,-34,)| Show InChI InChI=1S/C22H19F2N/c23-17-9-5-15(6-10-17)21-19-13-1-2-14(4-3-13)20(19)22(25-21)16-7-11-18(24)12-8-16/h5-14,25H,1-4H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	0.120	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherche Servier Curated by ChEMBL					Assay Description Tested in vitro for inhibition against Prostaglandin G/H synthase 2 in human blood (95% confidence limits)				J Med Chem 43: 4582-93 (2001) BindingDB Entry DOI: 10.7270/Q23B60T1
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Mus musculus (Mouse))	BDBM50094551 (3,5-Bis-(4-fluoro-phenyl)-4-aza-tricyclo[5.2.2.0*2...) Show SMILES Fc1ccc(cc1)-c1[nH]c(c2C3CCC(CC3)c12)-c1ccc(F)cc1 |(21.01,-36.41,;22.48,-35.94,;22.8,-34.43,;24.27,-33.96,;25.41,-35,;25.09,-36.5,;23.63,-36.98,;26.88,-34.53,;28.12,-35.45,;29.38,-34.55,;28.9,-33.08,;29.67,-31.77,;28.93,-30.43,;27.39,-30.42,;26.61,-31.74,;27.93,-30.96,;28.33,-32.53,;27.36,-33.07,;30.84,-35.03,;31.15,-36.54,;32.61,-37.02,;33.76,-36,;35.23,-36.48,;33.44,-34.48,;31.98,-34,)| Show InChI InChI=1S/C22H19F2N/c23-17-9-5-15(6-10-17)21-19-13-1-2-14(4-3-13)20(19)22(25-21)16-7-11-18(24)12-8-16/h5-14,25H,1-4H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherche Servier Curated by ChEMBL					Assay Description Inhibition against prostaglandin G/H synthase 2 from mouse resident macrophages				J Med Chem 43: 4582-93 (2001) BindingDB Entry DOI: 10.7270/Q23B60T1
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Mus musculus (Mouse))	BDBM50094542 (1,3-Diphenyl-2,4,5,6-tetrahydro-cyclopenta[c]pyrro...) Show SMILES C1Cc2c(C1)c([nH]c2-c1ccccc1)-c1ccccc1 Show InChI InChI=1S/C19H17N/c1-3-8-14(9-4-1)18-16-12-7-13-17(16)19(20-18)15-10-5-2-6-11-15/h1-6,8-11,20H,7,12-13H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	0.700	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherche Servier Curated by ChEMBL					Assay Description Inhibition against prostaglandin G/H synthase 2 from mouse resident macrophages				J Med Chem 43: 4582-93 (2001) BindingDB Entry DOI: 10.7270/Q23B60T1
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Mus musculus)	BDBM11639 (4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...) Show SMILES Cc1ccc(cc1)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F Show InChI InChI=1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18,19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	0.700	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherche Servier Curated by ChEMBL					Assay Description Tested for inhibition against Prostaglandin G/H synthase 2 from mouse resident macrophages				J Med Chem 43: 4582-93 (2001) BindingDB Entry DOI: 10.7270/Q23B60T1
					More data for this Ligand-Target Pair
Prolyl endopeptidase (Rattus norvegicus)	BDBM50051520 (CHEMBL305681 | [(2S,3aS,7aS)-2-(Pyrrolidine-1-carb...) Show SMILES FC(F)(F)c1cccc(c1)[C@H]1C[C@H]1C(=O)N1[C@H]2CCCC[C@H]2C[C@H]1C(=O)N1CCCC1 Show InChI InChI=1S/C24H29F3N2O2/c25-24(26,27)17-8-5-7-15(12-17)18-14-19(18)22(30)29-20-9-2-1-6-16(20)13-21(29)23(31)28-10-3-4-11-28/h5,7-8,12,16,18-21H,1-4,6,9-11,13-14H2/t16-,18+,19+,20-,21-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.900	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherche Servier Curated by ChEMBL					Assay Description Inhibitory activity of the compound was evaluated against Post-proline cleaving enzyme from rat cortex				J Med Chem 39: 2379-91 (1996) Article DOI: 10.1021/jm950858c BindingDB Entry DOI: 10.7270/Q2RF5T4J
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Homo sapiens (Human))	BDBM50094539 (3,5-Bis-(4-fluoro-phenyl)-4-aza-tricyclo[5.2.1.0*2...) Show SMILES Fc1ccc(cc1)-c1[nH]c(c2C3CCC(C3)c12)-c1ccc(F)cc1 Show InChI InChI=1S/C21H17F2N/c22-16-7-3-12(4-8-16)20-18-14-1-2-15(11-14)19(18)21(24-20)13-5-9-17(23)10-6-13/h3-10,14-15,24H,1-2,11H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherche Servier Curated by ChEMBL					Assay Description Tested in vitro for inhibition against Prostaglandin G/H synthase 1 in human blood				J Med Chem 43: 4582-93 (2001) BindingDB Entry DOI: 10.7270/Q23B60T1
					More data for this Ligand-Target Pair
Prolyl endopeptidase (Rattus norvegicus)	BDBM50051511 (CHEMBL80684 | [(1R,2S)-2-(4-Fluoro-phenyl)-cyclopr...) Show SMILES Fc1ccc(cc1)[C@H]1C[C@H]1C(=O)N1[C@H]2CCCC[C@H]2C[C@H]1C(=O)N1CCCC1 Show InChI InChI=1S/C23H29FN2O2/c24-17-9-7-15(8-10-17)18-14-19(18)22(27)26-20-6-2-1-5-16(20)13-21(26)23(28)25-11-3-4-12-25/h7-10,16,18-21H,1-6,11-14H2/t16-,18+,19+,20-,21-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherche Servier Curated by ChEMBL					Assay Description Inhibitory activity of the compound was evaluated against Post-proline cleaving enzyme from rat cortex				J Med Chem 39: 2379-91 (1996) Article DOI: 10.1021/jm950858c BindingDB Entry DOI: 10.7270/Q2RF5T4J
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Mus musculus (Mouse))	BDBM50094539 (3,5-Bis-(4-fluoro-phenyl)-4-aza-tricyclo[5.2.1.0*2...) Show SMILES Fc1ccc(cc1)-c1[nH]c(c2C3CCC(C3)c12)-c1ccc(F)cc1 Show InChI InChI=1S/C21H17F2N/c22-16-7-3-12(4-8-16)20-18-14-1-2-15(11-14)19(18)21(24-20)13-5-9-17(23)10-6-13/h3-10,14-15,24H,1-2,11H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherche Servier Curated by ChEMBL					Assay Description Inhibition against prostaglandin G/H synthase 2 from mouse resident macrophages				J Med Chem 43: 4582-93 (2001) BindingDB Entry DOI: 10.7270/Q23B60T1
					More data for this Ligand-Target Pair
Angiotensin-converting enzyme (Oryctolagus cuniculus)	BDBM50367254 (ENALAPRILAT) Show SMILES C[C@H](N[C@@H](CCc1ccccc1)C(O)=O)C(=O)N1CCC[C@H]1C(O)=O |r| Show InChI InChI=1S/C18H24N2O5/c1-12(16(21)20-11-5-8-15(20)18(24)25)19-14(17(22)23)10-9-13-6-3-2-4-7-13/h2-4,6-7,12,14-15,19H,5,8-11H2,1H3,(H,22,23)(H,24,25)/t12-,14-,15-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase MCE KEGG MMDB PC cid PC sid PDB UniChem Similars	PubMed	n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Chimie des Substances Naturelles Curated by ChEMBL					Assay Description In vitro activity against angiotensin I converting enzyme especially against Hip-His-Leu residues				J Med Chem 34: 663-9 (1991) BindingDB Entry DOI: 10.7270/Q21V5FKF
					More data for this Ligand-Target Pair
Prolyl endopeptidase (Rattus norvegicus)	BDBM50051523 (((1R,2S)-2-Phenyl-cyclopropyl)-[(2S,3aS,7aS)-2-(py...) Show SMILES O=C([C@@H]1C[C@@H]1c1ccccc1)N1[C@H]2CCCC[C@H]2C[C@H]1C(=O)N1CCCC1 Show InChI InChI=1S/C23H30N2O2/c26-22(19-15-18(19)16-8-2-1-3-9-16)25-20-11-5-4-10-17(20)14-21(25)23(27)24-12-6-7-13-24/h1-3,8-9,17-21H,4-7,10-15H2/t17-,18+,19+,20-,21-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherche Servier Curated by ChEMBL					Assay Description Inhibitory activity of the compound was evaluated against Post-proline cleaving enzyme from rat cortex				J Med Chem 39: 2379-91 (1996) Article DOI: 10.1021/jm950858c BindingDB Entry DOI: 10.7270/Q2RF5T4J
					More data for this Ligand-Target Pair
Prolyl endopeptidase (Rattus norvegicus)	BDBM50051504 (((1R,2S)-2-Phenyl-cyclopropyl)-[(2S,3aS,7aS)-2-(th...) Show SMILES O=C([C@@H]1C[C@@H]1c1ccccc1)N1[C@H]2CCCC[C@H]2C[C@H]1C(=O)N1CCSC1 Show InChI InChI=1S/C22H28N2O2S/c25-21(18-13-17(18)15-6-2-1-3-7-15)24-19-9-5-4-8-16(19)12-20(24)22(26)23-10-11-27-14-23/h1-3,6-7,16-20H,4-5,8-14H2/t16-,17+,18+,19-,20-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherche Servier Curated by ChEMBL					Assay Description Inhibitory activity of the compound was evaluated against Post-proline cleaving enzyme from rat cortex				J Med Chem 39: 2379-91 (1996) Article DOI: 10.1021/jm950858c BindingDB Entry DOI: 10.7270/Q2RF5T4J
					More data for this Ligand-Target Pair
Prolyl endopeptidase (Rattus norvegicus)	BDBM50051515 (CHEMBL80698 | [(2S,3aS,7aS)-2-(Pyrrolidine-1-carbo...) Show SMILES O=C([C@@H]1C[C@@H]1c1cccs1)N1[C@H]2CCCC[C@H]2C[C@H]1C(=O)N1CCCC1 Show InChI InChI=1S/C21H28N2O2S/c24-20(16-13-15(16)19-8-5-11-26-19)23-17-7-2-1-6-14(17)12-18(23)21(25)22-9-3-4-10-22/h5,8,11,14-18H,1-4,6-7,9-10,12-13H2/t14-,15-,16+,17-,18-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherche Servier Curated by ChEMBL					Assay Description Inhibitory activity of the compound was evaluated against Post-proline cleaving enzyme from rat cortex				J Med Chem 39: 2379-91 (1996) Article DOI: 10.1021/jm950858c BindingDB Entry DOI: 10.7270/Q2RF5T4J
					More data for this Ligand-Target Pair
Prolyl endopeptidase (Rattus norvegicus)	BDBM50051506 (((1R,2S)-2-Phenyl-cyclopropyl)-[(S)-3-(pyrrolidine...) Show SMILES O=C([C@@H]1C[C@@H]1c1ccccc1)N1C2CCC(C2)[C@H]1C(=O)N1CCCC1 Show InChI InChI=1S/C21H26N2O2/c24-20(18-13-17(18)14-6-2-1-3-7-14)23-16-9-8-15(12-16)19(23)21(25)22-10-4-5-11-22/h1-3,6-7,15-19H,4-5,8-13H2/t15?,16?,17-,18-,19+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherche Servier Curated by ChEMBL					Assay Description Inhibitory activity of the compound was evaluated against Post-proline cleaving enzyme from rat cortex				J Med Chem 39: 2379-91 (1996) Article DOI: 10.1021/jm950858c BindingDB Entry DOI: 10.7270/Q2RF5T4J
					More data for this Ligand-Target Pair
Prolyl endopeptidase (Rattus norvegicus)	BDBM50051516 (CHEMBL79213 | [(2S,3aS,7aS)-2-(Pyrrolidine-1-carbo...) Show SMILES Cc1ccc(cc1)[C@H]1C[C@H]1C(=O)N1[C@H]2CCCC[C@H]2C[C@H]1C(=O)N1CCCC1 Show InChI InChI=1S/C24H32N2O2/c1-16-8-10-17(11-9-16)19-15-20(19)23(27)26-21-7-3-2-6-18(21)14-22(26)24(28)25-12-4-5-13-25/h8-11,18-22H,2-7,12-15H2,1H3/t18-,19+,20+,21-,22-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherche Servier Curated by ChEMBL					Assay Description Inhibitory activity of the compound was evaluated against Post-proline cleaving enzyme from rat cortex				J Med Chem 39: 2379-91 (1996) Article DOI: 10.1021/jm950858c BindingDB Entry DOI: 10.7270/Q2RF5T4J
					More data for this Ligand-Target Pair
Angiotensin-converting enzyme (Oryctolagus cuniculus)	BDBM50011365 (1-[2-(1-Carboxy-butylamino)-propionyl]-octahydro-i...) Show SMILES CCCC(N[C@@H](C)C(=O)N1C2CCCCC2CC1C(O)=O)C(O)=O Show InChI InChI=1S/C17H28N2O5/c1-3-6-12(16(21)22)18-10(2)15(20)19-13-8-5-4-7-11(13)9-14(19)17(23)24/h10-14,18H,3-9H2,1-2H3,(H,21,22)(H,23,24)/t10-,11?,12?,13?,14?/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Chimie des Substances Naturelles Curated by ChEMBL					Assay Description In vitro activity against angiotensin I converting enzyme especially against Hip-His-Leu residues				J Med Chem 34: 663-9 (1991) BindingDB Entry DOI: 10.7270/Q21V5FKF
					More data for this Ligand-Target Pair
Angiotensin-converting enzyme (Oryctolagus cuniculus)	BDBM50011362 (1-(3-Mercapto-2-methyl-propionyl)-pyrrolidine-2-ca...) Show SMILES C[C@@H](CS)C(=O)N1CCCC1C(O)=O Show InChI InChI=1S/C9H15NO3S/c1-6(5-14)8(11)10-4-2-3-7(10)9(12)13/h6-7,14H,2-5H2,1H3,(H,12,13)/t6-,7?/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Chimie des Substances Naturelles Curated by ChEMBL					Assay Description In vitro activity against angiotensin I converting enzyme especially against Hip-His-Leu residues				J Med Chem 34: 663-9 (1991) BindingDB Entry DOI: 10.7270/Q21V5FKF
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Mus musculus (Mouse))	BDBM50094540 (1,3-diphenyl-4,5,6,7-tetrahydro-2H-isoindole | CHE...) Show SMILES C1CCc2c(C1)c([nH]c2-c1ccccc1)-c1ccccc1 Show InChI InChI=1S/C20H19N/c1-3-9-15(10-4-1)19-17-13-7-8-14-18(17)20(21-19)16-11-5-2-6-12-16/h1-6,9-12,21H,7-8,13-14H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherche Servier Curated by ChEMBL					Assay Description Inhibition against prostaglandin G/H synthase 2 from mouse resident macrophages				J Med Chem 43: 4582-93 (2001) BindingDB Entry DOI: 10.7270/Q23B60T1
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Mus musculus (Mouse))	BDBM50094546 (3,5-Diphenyl-4-aza-tricyclo[5.2.2.0*2,6*]undeca-2,...) Show SMILES C1CC2CCC1c1c([nH]c(c21)-c1ccccc1)-c1ccccc1 |(14.74,-30.53,;13.2,-30.52,;12.42,-31.84,;13.75,-31.06,;14.15,-32.63,;15.49,-31.87,;14.71,-33.19,;15.19,-34.65,;13.94,-35.55,;12.69,-34.64,;13.18,-33.17,;11.23,-35.11,;10.08,-34.06,;8.61,-34.53,;8.28,-36.04,;9.44,-37.08,;10.9,-36.61,;16.65,-35.13,;16.96,-36.64,;18.43,-37.13,;19.58,-36.1,;19.26,-34.58,;17.8,-34.11,)| Show InChI InChI=1S/C22H21N/c1-3-7-17(8-4-1)21-19-15-11-13-16(14-12-15)20(19)22(23-21)18-9-5-2-6-10-18/h1-10,15-16,23H,11-14H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherche Servier Curated by ChEMBL					Assay Description Inhibition against prostaglandin G/H synthase 2 from mouse resident macrophages				J Med Chem 43: 4582-93 (2001) BindingDB Entry DOI: 10.7270/Q23B60T1
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Mus musculus (Mouse))	BDBM50094563 (1,3-Di-p-tolyl-4,5,6,7-tetrahydro-2H-isoindole | 1...) Show SMILES Cc1ccc(cc1)-c1[nH]c(c2CCCCc12)-c1ccc(C)cc1 Show InChI InChI=1S/C22H23N/c1-15-7-11-17(12-8-15)21-19-5-3-4-6-20(19)22(23-21)18-13-9-16(2)10-14-18/h7-14,23H,3-6H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.67	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherche Servier Curated by ChEMBL					Assay Description Inhibition against prostaglandin G/H synthase 2 from mouse resident macrophages				J Med Chem 43: 4582-93 (2001) BindingDB Entry DOI: 10.7270/Q23B60T1
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Mus musculus (Mouse))	BDBM50094534 (1,3-Bis-(4-fluoro-phenyl)-4,5,6,7-tetrahydro-2H-is...) Show SMILES Fc1ccc(cc1)-c1[nH]c(c2CCCCc12)-c1ccc(F)cc1 Show InChI InChI=1S/C20H17F2N/c21-15-9-5-13(6-10-15)19-17-3-1-2-4-18(17)20(23-19)14-7-11-16(22)12-8-14/h5-12,23H,1-4H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.70	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherche Servier Curated by ChEMBL					Assay Description Inhibition against prostaglandin G/H synthase 2 from mouse resident macrophages				J Med Chem 43: 4582-93 (2001) BindingDB Entry DOI: 10.7270/Q23B60T1
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Mus musculus (Mouse))	BDBM50094532 (1,3-Diphenyl-4,5,6,7-tetrahydro-isoindol-2-ylamine...) Show SMILES Nn1c(c2CCCCc2c1-c1ccccc1)-c1ccccc1 Show InChI InChI=1S/C20H20N2/c21-22-19(15-9-3-1-4-10-15)17-13-7-8-14-18(17)20(22)16-11-5-2-6-12-16/h1-6,9-12H,7-8,13-14,21H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.80	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherche Servier Curated by ChEMBL					Assay Description Inhibition against prostaglandin G/H synthase 2 from mouse resident macrophages				J Med Chem 43: 4582-93 (2001) BindingDB Entry DOI: 10.7270/Q23B60T1
					More data for this Ligand-Target Pair
Angiotensin-converting enzyme (Oryctolagus cuniculus)	BDBM50011361 (1-[2-(1-Carboxy-butylamino)-acetyl]-octahydro-indo...) Show SMILES CCC[C@H](NCC(=O)N1C2CCCCC2C[C@H]1C(O)=O)C(O)=O |r| Show InChI InChI=1S/C16H26N2O5/c1-2-5-11(15(20)21)17-9-14(19)18-12-7-4-3-6-10(12)8-13(18)16(22)23/h10-13,17H,2-9H2,1H3,(H,20,21)(H,22,23)/t10?,11-,12?,13-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.90	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Chimie des Substances Naturelles Curated by ChEMBL					Assay Description In vitro activity against angiotensin I converting enzyme especially against Hip-His-Leu residues				J Med Chem 34: 663-9 (1991) BindingDB Entry DOI: 10.7270/Q21V5FKF
					More data for this Ligand-Target Pair
Prolyl endopeptidase (Rattus norvegicus)	BDBM50051508 (CHEMBL75968 | [(2S,3aS,7aS)-2-(Isoxazolidine-2-car...) Show SMILES O=C([C@@H]1C[C@@H]1c1ccccc1)N1[C@H]2CCCC[C@H]2C[C@H]1C(=O)N1CCCO1 Show InChI InChI=1S/C22H28N2O3/c25-21(18-14-17(18)15-7-2-1-3-8-15)24-19-10-5-4-9-16(19)13-20(24)22(26)23-11-6-12-27-23/h1-3,7-8,16-20H,4-6,9-14H2/t16-,17+,18+,19-,20-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherche Servier Curated by ChEMBL					Assay Description Inhibitory activity of the compound was evaluated against Post-proline cleaving enzyme from rat cortex				J Med Chem 39: 2379-91 (1996) Article DOI: 10.1021/jm950858c BindingDB Entry DOI: 10.7270/Q2RF5T4J
					More data for this Ligand-Target Pair
Prolyl endopeptidase (Rattus norvegicus)	BDBM50051489 (((1R,2S)-2-Phenyl-cyclopropyl)-[(2S,3aS,7aS)-2-(py...) Show SMILES O=C([C@@H]1C[C@@H]1c1ccccc1)N1[C@H]2CCCC[C@H]2C[C@H]1C(=O)n1cccc1 Show InChI InChI=1S/C23H26N2O2/c26-22(19-15-18(19)16-8-2-1-3-9-16)25-20-11-5-4-10-17(20)14-21(25)23(27)24-12-6-7-13-24/h1-3,6-9,12-13,17-21H,4-5,10-11,14-15H2/t17-,18+,19+,20-,21-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.30	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherche Servier Curated by ChEMBL					Assay Description Inhibitory activity of the compound was evaluated against Post-proline cleaving enzyme from rat cortex				J Med Chem 39: 2379-91 (1996) Article DOI: 10.1021/jm950858c BindingDB Entry DOI: 10.7270/Q2RF5T4J
					More data for this Ligand-Target Pair
Prolyl endopeptidase (Rattus norvegicus)	BDBM50051483 (CHEMBL80865 | [(2S,3aS,7aS)-2-(2,5-Dihydro-pyrrole...) Show SMILES O=C([C@@H]1C[C@@H]1c1ccccc1)N1[C@H]2CCCC[C@H]2C[C@H]1C(=O)N1CC=CC1 |c:28| Show InChI InChI=1S/C23H28N2O2/c26-22(19-15-18(19)16-8-2-1-3-9-16)25-20-11-5-4-10-17(20)14-21(25)23(27)24-12-6-7-13-24/h1-3,6-9,17-21H,4-5,10-15H2/t17-,18+,19+,20-,21-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.40	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherche Servier Curated by ChEMBL					Assay Description Inhibitory activity of the compound was evaluated against Post-proline cleaving enzyme from rat cortex				J Med Chem 39: 2379-91 (1996) Article DOI: 10.1021/jm950858c BindingDB Entry DOI: 10.7270/Q2RF5T4J
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Mus musculus (Mouse))	BDBM50094558 (3,5-Diphenyl-4-aza-tricyclo[5.2.1.0*2,6*]deca-2,5-...) Show SMILES C1CC2CC1c1c([nH]c(c21)-c1ccccc1)-c1ccccc1 Show InChI InChI=1S/C21H19N/c1-3-7-14(8-4-1)20-18-16-11-12-17(13-16)19(18)21(22-20)15-9-5-2-6-10-15/h1-10,16-17,22H,11-13H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	2.60	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherche Servier Curated by ChEMBL					Assay Description Inhibition against prostaglandin G/H synthase 2 from mouse resident macrophages				J Med Chem 43: 4582-93 (2001) BindingDB Entry DOI: 10.7270/Q23B60T1
					More data for this Ligand-Target Pair
Prolyl endopeptidase (Rattus norvegicus)	BDBM50051544 (CHEMBL311848 | [(2S,3aS,7aS)-2-(2,3-Dihydro-pyrrol...) Show SMILES O=C([C@@H]1C[C@@H]1c1ccccc1)N1[C@H]2CCCC[C@H]2C[C@H]1C(=O)N1CCC=C1 |c:29| Show InChI InChI=1S/C23H28N2O2/c26-22(19-15-18(19)16-8-2-1-3-9-16)25-20-11-5-4-10-17(20)14-21(25)23(27)24-12-6-7-13-24/h1-3,6,8-9,12,17-21H,4-5,7,10-11,13-15H2/t17-,18+,19+,20-,21-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.70	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherche Servier Curated by ChEMBL					Assay Description Inhibitory activity of the compound was evaluated against Post-proline cleaving enzyme from rat cortex				J Med Chem 39: 2379-91 (1996) Article DOI: 10.1021/jm950858c BindingDB Entry DOI: 10.7270/Q2RF5T4J
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Mus musculus (Mouse))	BDBM50094548 (1,3-Bis-(4-fluoro-phenyl)-2,4,5,6-tetrahydro-cyclo...) Show SMILES Fc1ccc(cc1)-c1[nH]c(c2CCCc12)-c1ccc(F)cc1 Show InChI InChI=1S/C19H15F2N/c20-14-8-4-12(5-9-14)18-16-2-1-3-17(16)19(22-18)13-6-10-15(21)11-7-13/h4-11,22H,1-3H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	2.90	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherche Servier Curated by ChEMBL					Assay Description Inhibition against prostaglandin G/H synthase 2 from mouse resident macrophages				J Med Chem 43: 4582-93 (2001) BindingDB Entry DOI: 10.7270/Q23B60T1
					More data for this Ligand-Target Pair
Neutrophil elastase (Homo sapiens (Human))	BDBM50058491 (3-{4-[2-(4-{1-[4-(2-Carboxy-2-methyl-propane-1-sul...) Show SMILES CC(C)(CS(=O)(=O)c1ccc(OC(=O)C(C)(C)c2ccc(cc2)C(C)(C)C(=O)Oc2ccc(cc2)S(=O)(=O)CC(C)(C)C(O)=O)cc1)C(O)=O Show InChI InChI=1S/C36H42O12S2/c1-33(2,29(37)38)21-49(43,44)27-17-13-25(14-18-27)47-31(41)35(5,6)23-9-11-24(12-10-23)36(7,8)32(42)48-26-15-19-28(20-16-26)50(45,46)22-34(3,4)30(39)40/h9-20H,21-22H2,1-8H3,(H,37,38)(H,39,40)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherche Servier Curated by ChEMBL					Assay Description Inhibitory concentration against Human Leukocyte Elastase from human sputum				J Med Chem 40: 1906-18 (1997) Article DOI: 10.1021/jm960772z BindingDB Entry DOI: 10.7270/Q2MS3RW1
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Mus musculus (Mouse))	BDBM50094528 (5,6-Dimethyl-1,3-diphenyl-4,5,6,7-tetrahydro-2H-is...) Show SMILES CC1Cc2c(CC1C)c([nH]c2-c1ccccc1)-c1ccccc1 Show InChI InChI=1S/C22H23N/c1-15-13-19-20(14-16(15)2)22(18-11-7-4-8-12-18)23-21(19)17-9-5-3-6-10-17/h3-12,15-16,23H,13-14H2,1-2H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	3.10	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherche Servier Curated by ChEMBL					Assay Description Inhibition against prostaglandin G/H synthase 2 from mouse resident macrophages				J Med Chem 43: 4582-93 (2001) BindingDB Entry DOI: 10.7270/Q23B60T1
					More data for this Ligand-Target Pair
Prolyl endopeptidase (Rattus norvegicus)	BDBM50051513 (((1R,2S)-2-Phenyl-cyclopropyl)-[(S)-3-(thiazolidin...) Show SMILES O=C([C@@H]1C2CCC(CC2)N1C(=O)[C@@H]1C[C@@H]1c1ccccc1)N1CCSC1 |wU:12.13,2.1,14.17,(12.4,-6.2,;11.07,-5.43,;9.73,-6.18,;8.4,-5.41,;7.07,-6.18,;7.07,-7.72,;8.4,-8.5,;9.1,-6.34,;7.62,-6.74,;9.73,-7.72,;11.07,-8.52,;12.4,-7.75,;11.07,-10.06,;10.3,-11.39,;11.84,-11.39,;13.17,-12.17,;13.17,-13.71,;14.5,-14.46,;15.84,-13.69,;15.84,-12.14,;14.5,-11.37,;11.08,-3.89,;12.31,-2.98,;11.84,-1.5,;10.3,-1.48,;9.8,-2.95,)| Show InChI InChI=1S/C21H26N2O2S/c24-20(18-12-17(18)14-4-2-1-3-5-14)23-16-8-6-15(7-9-16)19(23)21(25)22-10-11-26-13-22/h1-5,15-19H,6-13H2/t15?,16?,17-,18-,19+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.10	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherche Servier Curated by ChEMBL					Assay Description Inhibitory activity of the compound was evaluated against Post-proline cleaving enzyme from rat cortex				J Med Chem 39: 2379-91 (1996) Article DOI: 10.1021/jm950858c BindingDB Entry DOI: 10.7270/Q2RF5T4J
					More data for this Ligand-Target Pair
Prolyl endopeptidase (Rattus norvegicus)	BDBM50051496 (CHEMBL310228 | [(S)-3-(Pyrrolidine-1-carbonyl)-2-a...) Show SMILES FC(F)(F)c1cccc(c1)[C@H]1C[C@H]1C(=O)N1C2CCC(CC2)[C@H]1C(=O)N1CCCC1 |wU:12.14,22.26,10.10,(17.13,-12.07,;15.8,-11.32,;15.78,-9.78,;16.2,-12.79,;14.47,-12.09,;14.47,-13.63,;13.14,-14.4,;11.81,-13.65,;11.81,-12.11,;13.14,-11.32,;10.48,-11.34,;8.94,-11.35,;9.71,-10.01,;9.71,-8.47,;11.04,-7.7,;8.38,-7.7,;7.05,-8.45,;5.72,-7.7,;5.72,-6.16,;7.05,-5.37,;6.26,-6.7,;7.75,-6.31,;8.38,-6.16,;9.71,-5.39,;11.04,-6.17,;9.71,-3.85,;10.97,-2.95,;10.48,-1.45,;8.97,-1.48,;8.48,-2.94,)| Show InChI InChI=1S/C23H27F3N2O2/c24-23(25,26)16-5-3-4-15(12-16)18-13-19(18)21(29)28-17-8-6-14(7-9-17)20(28)22(30)27-10-1-2-11-27/h3-5,12,14,17-20H,1-2,6-11,13H2/t14?,17?,18-,19-,20+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.20	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherche Servier Curated by ChEMBL					Assay Description Inhibitory activity of the compound was evaluated against Post-proline cleaving enzyme from rat cortex				J Med Chem 39: 2379-91 (1996) Article DOI: 10.1021/jm950858c BindingDB Entry DOI: 10.7270/Q2RF5T4J
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Mus musculus (Mouse))	BDBM50094535 (1,3-diphenyl-4,7-dihydro-2H-isoindole | CHEMBL1408...) Show SMILES C1C=CCc2c1c([nH]c2-c1ccccc1)-c1ccccc1 |c:1| Show InChI InChI=1S/C20H17N/c1-3-9-15(10-4-1)19-17-13-7-8-14-18(17)20(21-19)16-11-5-2-6-12-16/h1-12,21H,13-14H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	3.30	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherche Servier Curated by ChEMBL					Assay Description Inhibition against prostaglandin G/H synthase 2 from mouse resident macrophages				J Med Chem 43: 4582-93 (2001) BindingDB Entry DOI: 10.7270/Q23B60T1
					More data for this Ligand-Target Pair
Prolyl endopeptidase (Rattus norvegicus)	BDBM50051537 (CHEMBL80136 | [(1R,2S)-2-(4-Fluoro-phenyl)-cyclopr...) Show SMILES Fc1ccc(cc1)[C@H]1C[C@H]1C(=O)N1C2CCC(CC2)[C@H]1C(=O)N1CCCC1 |wU:9.11,19.23,7.7,(16.51,-14.29,;15.16,-13.54,;15.16,-11.98,;13.83,-11.22,;12.49,-11.99,;12.49,-13.54,;13.83,-14.31,;11.16,-11.22,;9.62,-11.23,;10.39,-9.89,;10.39,-8.35,;11.72,-7.58,;9.06,-7.58,;7.72,-8.35,;6.39,-7.58,;6.39,-6.03,;7.72,-5.26,;6.94,-6.59,;8.43,-6.18,;9.06,-6.03,;10.39,-5.26,;11.72,-6.04,;10.4,-3.72,;9.17,-2.81,;9.64,-1.34,;11.16,-1.33,;11.65,-2.81,)| Show InChI InChI=1S/C22H27FN2O2/c23-16-7-3-14(4-8-16)18-13-19(18)21(26)25-17-9-5-15(6-10-17)20(25)22(27)24-11-1-2-12-24/h3-4,7-8,15,17-20H,1-2,5-6,9-13H2/t15?,17?,18-,19-,20+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherche Servier Curated by ChEMBL					Assay Description Inhibitory activity of the compound was evaluated against Post-proline cleaving enzyme from rat cortex				J Med Chem 39: 2379-91 (1996) Article DOI: 10.1021/jm950858c BindingDB Entry DOI: 10.7270/Q2RF5T4J
					More data for this Ligand-Target Pair
Prolyl endopeptidase (Rattus norvegicus)	BDBM50051543 ((2-Benzyl-cyclopropyl)-[(S)-3-(pyrrolidine-1-carbo...) Show SMILES O=C([C@@H]1C2CCC(CC2)N1C(=O)C1CC1Cc1ccccc1)N1CCCC1 |wU:2.1,(13.05,-9.15,;11.72,-8.36,;10.39,-9.13,;9.06,-8.35,;7.73,-9.13,;7.73,-10.67,;9.06,-11.43,;9.76,-9.27,;8.28,-9.68,;10.39,-10.67,;11.72,-11.44,;13.05,-10.67,;11.72,-12.98,;10.95,-14.33,;12.49,-14.31,;13.82,-15.08,;13.81,-16.62,;15.13,-17.39,;15.12,-18.93,;13.77,-19.7,;12.44,-18.91,;12.47,-17.37,;11.74,-6.82,;12.98,-5.93,;12.49,-4.44,;10.97,-4.46,;10.5,-5.91,)| Show InChI InChI=1S/C23H30N2O2/c26-22(20-15-18(20)14-16-6-2-1-3-7-16)25-19-10-8-17(9-11-19)21(25)23(27)24-12-4-5-13-24/h1-3,6-7,17-21H,4-5,8-15H2/t17?,18?,19?,20?,21-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.20	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherche Servier Curated by ChEMBL					Assay Description Inhibitory activity of the compound was evaluated against Post-proline cleaving enzyme from rat cortex				J Med Chem 39: 2379-91 (1996) Article DOI: 10.1021/jm950858c BindingDB Entry DOI: 10.7270/Q2RF5T4J
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Mus musculus (Mouse))	BDBM50094561 (3,5-Bis-(4-fluoro-phenyl)-4-aza-tricyclo[5.2.1.0*2...) Show SMILES Fc1ccc(cc1)-c1[nH]c(c2C3CC(C=C3)c12)-c1ccc(F)cc1 |c:15| Show InChI InChI=1S/C21H15F2N/c22-16-7-3-12(4-8-16)20-18-14-1-2-15(11-14)19(18)21(24-20)13-5-9-17(23)10-6-13/h1-10,14-15,24H,11H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	4.5	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherche Servier Curated by ChEMBL					Assay Description Inhibition against prostaglandin G/H synthase 2 from mouse resident macrophages				J Med Chem 43: 4582-93 (2001) BindingDB Entry DOI: 10.7270/Q23B60T1
					More data for this Ligand-Target Pair
Prolyl endopeptidase (Rattus norvegicus)	BDBM50051484 (CHEMBL307938 | [(S)-3-(Pyrrolidine-1-carbonyl)-2-a...) Show SMILES O=C([C@@H]1C2CCC(CC2)N1C(=O)[C@@H]1C[C@@H]1c1cccs1)N1CCCC1 |wU:12.13,2.1,14.17,(12.52,-6.41,;11.18,-5.63,;9.85,-6.41,;8.52,-5.62,;7.19,-6.41,;7.19,-7.95,;8.52,-8.71,;9.22,-6.55,;7.75,-6.95,;9.85,-7.95,;11.18,-8.72,;12.52,-7.95,;11.18,-10.26,;10.41,-11.6,;11.96,-11.6,;13.29,-12.37,;13.45,-13.91,;14.95,-14.22,;15.72,-12.88,;14.69,-11.74,;11.21,-4.09,;9.97,-3.18,;10.44,-1.71,;11.96,-1.68,;12.45,-3.18,)| Show InChI InChI=1S/C20H26N2O2S/c23-19(16-12-15(16)17-4-3-11-25-17)22-14-7-5-13(6-8-14)18(22)20(24)21-9-1-2-10-21/h3-4,11,13-16,18H,1-2,5-10,12H2/t13?,14?,15-,16+,18-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.80	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherche Servier Curated by ChEMBL					Assay Description Inhibitory activity of the compound was evaluated against Post-proline cleaving enzyme from rat cortex				J Med Chem 39: 2379-91 (1996) Article DOI: 10.1021/jm950858c BindingDB Entry DOI: 10.7270/Q2RF5T4J
					More data for this Ligand-Target Pair
Prolyl endopeptidase (Homo sapiens (Human))	BDBM50051484 (CHEMBL307938 | [(S)-3-(Pyrrolidine-1-carbonyl)-2-a...) Show SMILES O=C([C@@H]1C2CCC(CC2)N1C(=O)[C@@H]1C[C@@H]1c1cccs1)N1CCCC1 |wU:12.13,2.1,14.17,(12.52,-6.41,;11.18,-5.63,;9.85,-6.41,;8.52,-5.62,;7.19,-6.41,;7.19,-7.95,;8.52,-8.71,;9.22,-6.55,;7.75,-6.95,;9.85,-7.95,;11.18,-8.72,;12.52,-7.95,;11.18,-10.26,;10.41,-11.6,;11.96,-11.6,;13.29,-12.37,;13.45,-13.91,;14.95,-14.22,;15.72,-12.88,;14.69,-11.74,;11.21,-4.09,;9.97,-3.18,;10.44,-1.71,;11.96,-1.68,;12.45,-3.18,)| Show InChI InChI=1S/C20H26N2O2S/c23-19(16-12-15(16)17-4-3-11-25-17)22-14-7-5-13(6-8-14)18(22)20(24)21-9-1-2-10-21/h3-4,11,13-16,18H,1-2,5-10,12H2/t13?,14?,15-,16+,18-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.80	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherche Servier Curated by ChEMBL					Assay Description Inhibitory activity of the compound was evaluated against Post-proline cleaving enzyme from Flavobacterium meningosepticam				J Med Chem 39: 2379-91 (1996) Article DOI: 10.1021/jm950858c BindingDB Entry DOI: 10.7270/Q2RF5T4J
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Mus musculus (Mouse))	BDBM50094541 (1,3-Bis-(4-chloro-phenyl)-4,5,6,7-tetrahydro-2H-is...) Show SMILES Clc1ccc(cc1)-c1[nH]c(c2CCCCc12)-c1ccc(Cl)cc1 Show InChI InChI=1S/C20H17Cl2N/c21-15-9-5-13(6-10-15)19-17-3-1-2-4-18(17)20(23-19)14-7-11-16(22)12-8-14/h5-12,23H,1-4H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherche Servier Curated by ChEMBL					Assay Description Inhibition against prostaglandin G/H synthase 2 from mouse resident macrophages				J Med Chem 43: 4582-93 (2001) BindingDB Entry DOI: 10.7270/Q23B60T1
					More data for this Ligand-Target Pair
Prolyl endopeptidase (Rattus norvegicus)	BDBM50051486 (((1R,2S)-2-Naphthalen-2-yl-cyclopropyl)-[(S)-3-(py...) Show SMILES O=C([C@@H]1C[C@@H]1c1ccc2ccccc2c1)N1C2CCC(CC2)[C@H]1C(=O)N1CCCC1 |wU:2.1,22.27,4.5,(11.04,-7.7,;9.71,-8.47,;9.71,-10.01,;8.94,-11.35,;10.48,-11.34,;11.81,-12.11,;11.81,-13.65,;13.14,-14.4,;14.47,-13.63,;15.8,-14.4,;17.13,-13.61,;17.13,-12.07,;15.78,-11.32,;14.47,-12.09,;13.14,-11.32,;8.38,-7.7,;7.05,-8.45,;7.75,-6.3,;6.26,-6.7,;7.05,-5.37,;5.72,-6.16,;5.72,-7.7,;8.38,-6.16,;9.71,-5.39,;11.04,-6.17,;9.71,-3.85,;10.97,-2.95,;10.48,-1.45,;8.97,-1.48,;8.48,-2.94,)| Show InChI InChI=1S/C26H30N2O2/c29-25(23-16-22(23)20-8-7-17-5-1-2-6-19(17)15-20)28-21-11-9-18(10-12-21)24(28)26(30)27-13-3-4-14-27/h1-2,5-8,15,18,21-24H,3-4,9-14,16H2/t18?,21?,22-,23-,24+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherche Servier Curated by ChEMBL					Assay Description Inhibitory activity of the compound was evaluated against Post-proline cleaving enzyme from rat cortex				J Med Chem 39: 2379-91 (1996) Article DOI: 10.1021/jm950858c BindingDB Entry DOI: 10.7270/Q2RF5T4J
					More data for this Ligand-Target Pair
Prolyl endopeptidase (Homo sapiens (Human))	BDBM50051518 (6,6,6-Trifluoro-5-phenyl-1-[(2S,3aS,7aS)-2-(pyrrol...) Show SMILES FC(F)(F)C(CCCC(=O)N1[C@H]2CCCC[C@H]2C[C@H]1C(=O)N1CCCC1)c1ccccc1 Show InChI InChI=1S/C25H33F3N2O2/c26-25(27,28)20(18-9-2-1-3-10-18)12-8-14-23(31)30-21-13-5-4-11-19(21)17-22(30)24(32)29-15-6-7-16-29/h1-3,9-10,19-22H,4-8,11-17H2/t19-,20?,21-,22-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherche Servier Curated by ChEMBL					Assay Description Inhibitory activity evaluated against Post-proline cleaving enzyme from Flavobacterium meningosepticum				J Med Chem 39: 2379-91 (1996) Article DOI: 10.1021/jm950858c BindingDB Entry DOI: 10.7270/Q2RF5T4J
					More data for this Ligand-Target Pair
Prolyl endopeptidase (Rattus norvegicus)	BDBM50051488 (((1R,2S)-2-Phenyl-cyclopropyl)-[(S)-3-(pyrrolidine...) Show SMILES O=C([C@@H]1C[C@@H]1c1ccccc1)N1C2CCC(CC2)[C@H]1C(=O)N1CCCC1 |wU:2.1,18.22,4.5,(12.37,-7.7,;11.04,-8.47,;11.04,-9.99,;10.27,-11.35,;11.81,-11.34,;13.14,-12.11,;13.14,-13.65,;14.47,-14.4,;15.8,-13.63,;15.8,-12.09,;14.47,-11.32,;9.71,-7.7,;8.38,-8.45,;7.05,-7.7,;7.05,-6.16,;8.38,-5.37,;7.61,-6.7,;9.08,-6.3,;9.71,-6.16,;11.04,-5.39,;12.37,-6.17,;11.06,-3.85,;9.82,-2.94,;10.3,-1.48,;11.81,-1.45,;12.3,-2.95,)| Show InChI InChI=1S/C22H28N2O2/c25-21(19-14-18(19)15-6-2-1-3-7-15)24-17-10-8-16(9-11-17)20(24)22(26)23-12-4-5-13-23/h1-3,6-7,16-20H,4-5,8-14H2/t16?,17?,18-,19-,20+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherche Servier Curated by ChEMBL					Assay Description Inhibitory activity of the compound was evaluated against Post-proline cleaving enzyme from rat cortex				J Med Chem 39: 2379-91 (1996) Article DOI: 10.1021/jm950858c BindingDB Entry DOI: 10.7270/Q2RF5T4J
					More data for this Ligand-Target Pair
Prolyl endopeptidase (Homo sapiens (Human))	BDBM50051540 ((R)-3-(Pyrrolidine-1-carbonyl)-2-aza-bicyclo[2.2.1...) Show SMILES CC(C)(C)OC(=O)N1C2CCC(C2)[C@@H]1C(=O)N1CCCC1 Show InChI InChI=1S/C16H26N2O3/c1-16(2,3)21-15(20)18-12-7-6-11(10-12)13(18)14(19)17-8-4-5-9-17/h11-13H,4-10H2,1-3H3/t11?,12?,13-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.5	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherche Servier Curated by ChEMBL					Assay Description Inhibitory activity evaluated against Post-proline cleaving enzyme from Flavobacterium meningosepticum				J Med Chem 39: 2379-91 (1996) Article DOI: 10.1021/jm950858c BindingDB Entry DOI: 10.7270/Q2RF5T4J
					More data for this Ligand-Target Pair
Prolyl endopeptidase (Homo sapiens (Human))	BDBM50454200 (CHEMBL2369824) Show SMILES [#7]-[#6@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#6](=O)-[#7]-1-[#6]-[#6]-[#6]-[#6@H]-1-[#6](=O)-[#7]-1-[#6]-[#6@H](-[#8])-[#6]-[#6@H]-1-[#6](=O)-[#7]-[#6]-[#6](=O)-[#7]-[#6](-[#6]-c1cccs1)-[#6](=O)-[#7]-[#6@@H](-[#6]-[#8])-[#6](=O)-[#7]-1-[#6]-c2ccccc2-[#6]-[#6@@H]-1-[#6](=O)-[#7]-1-[#6@@H](-[#6]-c2ccccc-12)-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#6](-[#8])=O Show InChI InChI=1S/C59H83N19O13S/c60-37(14-5-19-67-57(61)62)48(82)72-38(15-6-20-68-58(63)64)52(86)75-22-8-18-43(75)54(88)77-30-35(80)26-44(77)50(84)70-28-47(81)71-40(27-36-13-9-23-92-36)49(83)74-41(31-79)53(87)76-29-34-12-2-1-10-32(34)24-46(76)55(89)78-42-17-4-3-11-33(42)25-45(78)51(85)73-39(56(90)91)16-7-21-69-59(65)66/h1-4,9-13,17,23,35,37-41,43-46,79-80H,5-8,14-16,18-22,24-31,60H2,(H,70,84)(H,71,81)(H,72,82)(H,73,85)(H,74,83)(H,90,91)(H4,61,62,67)(H4,63,64,68)(H4,65,66,69)/t35-,37-,38+,39+,40?,41+,43+,44+,45+,46-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.5	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherche Servier Curated by ChEMBL					Assay Description Inhibitory activity evaluated against Post-proline cleaving enzyme from Flavobacterium meningosepticum				J Med Chem 39: 2379-91 (1996) Article DOI: 10.1021/jm950858c BindingDB Entry DOI: 10.7270/Q2RF5T4J
					More data for this Ligand-Target Pair
Prolyl endopeptidase (Homo sapiens (Human))	BDBM50051487 (5,5-Dicyclopropyl-1-[(S)-3-(pyrrolidine-1-carbonyl...) Show SMILES O=C(CCCC(C1CC1)C1CC1)N1C2CCC(CC2)[C@H]1C(=O)N1CCCC1 |wU:19.23,(4.28,.47,;2.94,-.29,;2.93,-1.85,;1.6,-2.62,;1.59,-4.16,;.26,-4.93,;-1.08,-5.7,;-1.84,-7.04,;-2.61,-5.69,;1.59,-5.7,;2.36,-7.04,;3.13,-5.69,;1.6,.47,;.27,-.29,;-1.05,.47,;-1.05,2.01,;.27,2.78,;-.51,1.45,;.98,1.86,;1.6,2.01,;2.94,2.78,;4.28,2,;2.94,4.32,;1.71,5.24,;2.18,6.7,;3.72,6.71,;4.19,5.23,)| Show InChI InChI=1S/C23H36N2O2/c26-21(5-3-4-20(16-6-7-16)17-8-9-17)25-19-12-10-18(11-13-19)22(25)23(27)24-14-1-2-15-24/h16-20,22H,1-15H2/t18?,19?,22-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherche Servier Curated by ChEMBL					Assay Description Inhibitory activity evaluated against Post-proline cleaving enzyme from Flavobacterium meningosepticum				J Med Chem 39: 2379-91 (1996) Article DOI: 10.1021/jm950858c BindingDB Entry DOI: 10.7270/Q2RF5T4J
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 2 (Mus musculus (Mouse))	BDBM11639 (4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...) Show SMILES Cc1ccc(cc1)-c1cc(nn1-c1ccc(cc1)S(N)(=O)=O)C(F)(F)F Show InChI InChI=1S/C17H14F3N3O2S/c1-11-2-4-12(5-3-11)15-10-16(17(18,19)20)22-23(15)13-6-8-14(9-7-13)26(21,24)25/h2-10H,1H3,(H2,21,24,25)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB PubMed	n/a	n/a	9.30	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherche Servier Curated by ChEMBL					Assay Description Tested for inhibition against Prostaglandin G/H synthase 1 from mouse resident macrophages				J Med Chem 43: 4582-93 (2001) BindingDB Entry DOI: 10.7270/Q23B60T1
					More data for this Ligand-Target Pair				3D Structure (crystal)
Prostaglandin G/H synthase 2 (Mus musculus (Mouse))	BDBM50094536 (1,3-Diphenyl-2,3-dihydro-1H-isoindole | CHEMBL1412...) Show SMILES N1[C@@H](c2ccccc2[C@H]1c1ccccc1)c1ccccc1 Show InChI InChI=1S/C20H17N/c1-3-9-15(10-4-1)19-17-13-7-8-14-18(17)20(21-19)16-11-5-2-6-12-16/h1-14,19-21H/t19-,20-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherche Servier Curated by ChEMBL					Assay Description Inhibition against prostaglandin G/H synthase 2 from mouse resident macrophages				J Med Chem 43: 4582-93 (2001) BindingDB Entry DOI: 10.7270/Q23B60T1
					More data for this Ligand-Target Pair

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