Compile Data Set for Download or QSAR

Found 302 hits with Last Name = 'lee' and Initial = 'cw'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Amyloid-beta precursor protein (Homo sapiens (Human))	BDBM50101410 ((trans,trans)-1-bromo-2,5-bis-(3-hydroxycarbonyl-4...) Show SMILES OC(=O)c1cc(\C=C\c2ccc(\C=C\c3ccc(O)c(c3)C(O)=O)c(Br)c2)ccc1O Show InChI InChI=1S/C24H17BrO6/c25-20-13-16(2-1-14-5-9-21(26)18(11-14)23(28)29)4-8-17(20)7-3-15-6-10-22(27)19(12-15)24(30)31/h1-13,26-27H,(H,28,29)(H,30,31)/b2-1+,7-3+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	0.110	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Inhibitory activity against binding of [125I]-IMSB to amyloid beta in brain				J Med Chem 44: 2270-5 (2001) BindingDB Entry DOI: 10.7270/Q22J6B4Z
					More data for this Ligand-Target Pair
Amyloid-beta precursor protein (Homo sapiens (Human))	BDBM50101411 (5-[2-bromo-4-(3-carboxy-4-hydroxyphenethyl)pheneth...) Show SMILES OC(=O)c1cc(\C=C/c2ccc(\C=C/c3ccc(O)c(c3)C(O)=O)c(Br)c2)ccc1O Show InChI InChI=1S/C24H17BrO6/c25-20-13-16(2-1-14-5-9-21(26)18(11-14)23(28)29)4-8-17(20)7-3-15-6-10-22(27)19(12-15)24(30)31/h1-13,26-27H,(H,28,29)(H,30,31)/b2-1-,7-3-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.130	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Inhibitory activity against binding of [125I]-IMSB to amyloid beta in brain				J Med Chem 44: 2270-5 (2001) BindingDB Entry DOI: 10.7270/Q22J6B4Z
					More data for this Ligand-Target Pair
Amyloid-beta precursor protein (Homo sapiens (Human))	BDBM50100131 (5-(Biphenyl-4-ylazo)-bis (2-hydroxy-benzoic acid)(...) Show SMILES OC(=O)c1cc(ccc1O)N=Nc1ccc(cc1)-c1ccc(cc1)N=Nc1ccc(O)c(c1)C(O)=O |w:25.28,11.12| Show InChI InChI=1S/C26H18N4O6/c31-23-11-9-19(13-21(23)25(33)34)29-27-17-5-1-15(2-6-17)16-3-7-18(8-4-16)28-30-20-10-12-24(32)22(14-20)26(35)36/h1-14,31-32H,(H,33,34)(H,35,36)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	0.140	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Inhibitory activity against binding of [125I]-IMSB to amyloid beta in brain				J Med Chem 44: 2270-5 (2001) BindingDB Entry DOI: 10.7270/Q22J6B4Z
					More data for this Ligand-Target Pair
Amyloid-beta precursor protein (Homo sapiens (Human))	BDBM50101413 (5-[2-bromo-4-(3-carboxy-4-hydroxyphenethyl)pheneth...) Show SMILES OC(=O)c1cc(\C=C\c2ccc(\C=C/c3ccc(O)c(c3)C(O)=O)c(Br)c2)ccc1O Show InChI InChI=1S/C24H17BrO6/c25-20-13-16(2-1-14-5-9-21(26)18(11-14)23(28)29)4-8-17(20)7-3-15-6-10-22(27)19(12-15)24(30)31/h1-13,26-27H,(H,28,29)(H,30,31)/b2-1+,7-3-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.190	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Inhibitory activity against binding of [125I]-IMSB to amyloid beta in brain				J Med Chem 44: 2270-5 (2001) BindingDB Entry DOI: 10.7270/Q22J6B4Z
					More data for this Ligand-Target Pair
Amyloid-beta precursor protein (Homo sapiens (Human))	BDBM50101412 (5-[2-bromo-4-(3-carboxy-4-hydroxyphenethyl)pheneth...) Show SMILES OC(=O)c1cc(\C=C/c2ccc(\C=C\c3ccc(O)c(c3)C(O)=O)c(Br)c2)ccc1O Show InChI InChI=1S/C24H17BrO6/c25-20-13-16(2-1-14-5-9-21(26)18(11-14)23(28)29)4-8-17(20)7-3-15-6-10-22(27)19(12-15)24(30)31/h1-13,26-27H,(H,28,29)(H,30,31)/b2-1-,7-3+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.270	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Inhibitory activity against binding of [125I]-IMSB to amyloid beta in brain				J Med Chem 44: 2270-5 (2001) BindingDB Entry DOI: 10.7270/Q22J6B4Z
					More data for this Ligand-Target Pair
Amyloid-beta precursor protein (Homo sapiens (Human))	BDBM50100130 (4-(6-Iodobenzo[d]thiazol-2-yl)-N,N-dimethylaniline...) Show SMILES CN(C)c1ccc(cc1)-c1nc2ccc(I)cc2s1 Show InChI InChI=1S/C15H13IN2S/c1-18(2)12-6-3-10(4-7-12)15-17-13-8-5-11(16)9-14(13)19-15/h3-9H,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.900	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Inhibition constant against [125I]-7 (TZDM) binding to Amyloid beta 1-40 aggregates				J Med Chem 46: 237-43 (2003) Article DOI: 10.1021/jm020351j BindingDB Entry DOI: 10.7270/Q2WH2PBC
					More data for this Ligand-Target Pair
Protein kinase C alpha type (Homo sapiens (Human))	BDBM50310131 ((2-hydroxy-4-(3-isobutyl-5-methylhexylidene)-5-oxo...) Show SMILES CC(C)CC(C\C=C1\CC(O)(COC(=O)C(C)(C)C)OC1=O)CC(C)C Show InChI InChI=1S/C21H36O5/c1-14(2)10-16(11-15(3)4)8-9-17-12-21(24,26-18(17)22)13-25-19(23)20(5,6)7/h9,14-16,24H,8,10-13H2,1-7H3/b17-9-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Displacement of [20-3H]phorbol 12,13-dibutyrate from recombinant PKCalpha				Bioorg Med Chem Lett 20: 1008-12 (2010) Article DOI: 10.1016/j.bmcl.2009.12.058 BindingDB Entry DOI: 10.7270/Q29C6XJT
					More data for this Ligand-Target Pair
Protein kinase C alpha type (Homo sapiens (Human))	BDBM50310107 ((E)-(2-(hydroxymethyl)-4-(8-(nonyloxy)octylidene)-...) Show SMILES CCCCCCCCCOCCCCCCC\C=C1/CC(CO)(COC(=O)C(C)(C)C)OC1=O Show InChI InChI=1S/C28H50O6/c1-5-6-7-8-10-13-16-19-32-20-17-14-11-9-12-15-18-24-21-28(22-29,34-25(24)30)23-33-26(31)27(2,3)4/h18,29H,5-17,19-23H2,1-4H3/b24-18+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Displacement of [20-3H]phorbol 12,13-dibutyrate from recombinant PKCalpha				Bioorg Med Chem Lett 20: 1008-12 (2010) Article DOI: 10.1016/j.bmcl.2009.12.058 BindingDB Entry DOI: 10.7270/Q29C6XJT
					More data for this Ligand-Target Pair
cGMP-dependent 3',5'-cyclic phosphodiesterase (Rattus norvegicus)	BDBM107767 (US11419874, PF-05180999 | US8598155, 2) Show SMILES Cc1nc(-c2cnn(C)c2-c2ccc(cn2)C(F)(F)F)c2c(ncnn12)N1CCC1 Show InChI InChI=1S/C19H17F3N8/c1-11-27-15(17-18(29-6-3-7-29)24-10-26-30(11)17)13-9-25-28(2)16(13)14-5-4-12(8-23-14)19(20,21)22/h4-5,8-10H,3,6-7H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	4.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of radiolabeled 4-(azetidin-1-yl)-3-[5-[4-(trifluoromethyl)phenyl]-1H-pyrazol-4-yl]-1-(tritritiomethyl)pyrazolo[3,4-d]pyrimidine from PD...				J Med Chem 61: 1001-1018 (2018) Article DOI: 10.1021/acs.jmedchem.7b01466 BindingDB Entry DOI: 10.7270/Q2ZS2ZZ4
					More data for this Ligand-Target Pair
Protein kinase C alpha type (Homo sapiens (Human))	BDBM50310104 ((E)-(2-(hydroxymethyl)-4-(16-methoxyhexadecylidene...) Show SMILES COCCCCCCCCCCCCCCC\C=C1/CC(CO)(COC(=O)C(C)(C)C)OC1=O Show InChI InChI=1S/C28H50O6/c1-27(2,3)26(31)33-23-28(22-29)21-24(25(30)34-28)19-17-15-13-11-9-7-5-6-8-10-12-14-16-18-20-32-4/h19,29H,5-18,20-23H2,1-4H3/b24-19+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Displacement of [20-3H]phorbol 12,13-dibutyrate from recombinant PKCalpha				Bioorg Med Chem Lett 20: 1008-12 (2010) Article DOI: 10.1016/j.bmcl.2009.12.058 BindingDB Entry DOI: 10.7270/Q29C6XJT
					More data for this Ligand-Target Pair
Protein kinase C alpha type (Homo sapiens (Human))	BDBM50310105 ((Z)-(2-(hydroxymethyl)-4-(16-methoxyhexadecylidene...) Show SMILES COCCCCCCCCCCCCCCC\C=C1\CC(CO)(COC(=O)C(C)(C)C)OC1=O Show InChI InChI=1S/C28H50O6/c1-27(2,3)26(31)33-23-28(22-29)21-24(25(30)34-28)19-17-15-13-11-9-7-5-6-8-10-12-14-16-18-20-32-4/h19,29H,5-18,20-23H2,1-4H3/b24-19-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Displacement of [20-3H]phorbol 12,13-dibutyrate from recombinant PKCalpha				Bioorg Med Chem Lett 20: 1008-12 (2010) Article DOI: 10.1016/j.bmcl.2009.12.058 BindingDB Entry DOI: 10.7270/Q29C6XJT
					More data for this Ligand-Target Pair
Protein kinase C alpha type (Homo sapiens (Human))	BDBM50310120 ((E)-(2-(hydroxymethyl)-5-oxo-4-(16-oxohexadecylide...) Show SMILES CC(C)(C)C(=O)OCC1(CO)C\C(=C/CCCCCCCCCCCCCCC=O)C(=O)O1 Show InChI InChI=1S/C27H46O6/c1-26(2,3)25(31)32-22-27(21-29)20-23(24(30)33-27)18-16-14-12-10-8-6-4-5-7-9-11-13-15-17-19-28/h18-19,29H,4-17,20-22H2,1-3H3/b23-18+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	6.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Displacement of [20-3H]phorbol 12,13-dibutyrate from recombinant PKCalpha				Bioorg Med Chem Lett 20: 1008-12 (2010) Article DOI: 10.1016/j.bmcl.2009.12.058 BindingDB Entry DOI: 10.7270/Q29C6XJT
					More data for this Ligand-Target Pair
Protein kinase C alpha type (Homo sapiens (Human))	BDBM50310115 ((E)-(4-(16-hydroxyhexadecylidene)-2-(hydroxymethyl...) Show SMILES CC(C)(C)C(=O)OCC1(CO)C\C(=C/CCCCCCCCCCCCCCCO)C(=O)O1 Show InChI InChI=1S/C27H48O6/c1-26(2,3)25(31)32-22-27(21-29)20-23(24(30)33-27)18-16-14-12-10-8-6-4-5-7-9-11-13-15-17-19-28/h18,28-29H,4-17,19-22H2,1-3H3/b23-18+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Displacement of [20-3H]phorbol 12,13-dibutyrate from recombinant PKCalpha				Bioorg Med Chem Lett 20: 1008-12 (2010) Article DOI: 10.1016/j.bmcl.2009.12.058 BindingDB Entry DOI: 10.7270/Q29C6XJT
					More data for this Ligand-Target Pair
Protein kinase C alpha type (Homo sapiens (Human))	BDBM50310124 ((E)-methyl 16-(5-(hydroxymethyl)-2-oxo-5-(pivaloyl...) Show SMILES COC(=O)CCCCCCCCCCCCCC\C=C1/CC(CO)(COC(=O)C(C)(C)C)OC1=O Show InChI InChI=1S/C28H48O7/c1-27(2,3)26(32)34-22-28(21-29)20-23(25(31)35-28)18-16-14-12-10-8-6-5-7-9-11-13-15-17-19-24(30)33-4/h18,29H,5-17,19-22H2,1-4H3/b23-18+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Displacement of [20-3H]phorbol 12,13-dibutyrate from recombinant PKCalpha				Bioorg Med Chem Lett 20: 1008-12 (2010) Article DOI: 10.1016/j.bmcl.2009.12.058 BindingDB Entry DOI: 10.7270/Q29C6XJT
					More data for this Ligand-Target Pair
Protein kinase C alpha type (Homo sapiens (Human))	BDBM50310101 ((Z)-(2-(hydroxymethyl)-5-oxo-4-tetradecylidenetetr...) Show SMILES CCCCCCCCCCCCC\C=C1\CC(CO)(COC(=O)C(C)(C)C)OC1=O Show InChI InChI=1S/C25H44O5/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-21-18-25(19-26,30-22(21)27)20-29-23(28)24(2,3)4/h17,26H,5-16,18-20H2,1-4H3/b21-17-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Displacement of [20-3H]phorbol 12,13-dibutyrate from recombinant PKCalpha				Bioorg Med Chem Lett 20: 1008-12 (2010) Article DOI: 10.1016/j.bmcl.2009.12.058 BindingDB Entry DOI: 10.7270/Q29C6XJT
					More data for this Ligand-Target Pair
Protein kinase C alpha type (Homo sapiens (Human))	BDBM50310112 ((E)-(2-(hydroxymethyl)-4-(4-(nonyloxy)butylidene)-...) Show SMILES CCCCCCCCCOCCC\C=C1/CC(CO)(COC(=O)C(C)(C)C)OC1=O Show InChI InChI=1S/C24H42O6/c1-5-6-7-8-9-10-12-15-28-16-13-11-14-20-17-24(18-25,30-21(20)26)19-29-22(27)23(2,3)4/h14,25H,5-13,15-19H2,1-4H3/b20-14+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Displacement of [20-3H]phorbol 12,13-dibutyrate from recombinant PKCalpha				Bioorg Med Chem Lett 20: 1008-12 (2010) Article DOI: 10.1016/j.bmcl.2009.12.058 BindingDB Entry DOI: 10.7270/Q29C6XJT
					More data for this Ligand-Target Pair
Protein kinase C alpha type (Homo sapiens (Human))	BDBM50310110 ((E)-(2-(hydroxymethyl)-4-(8-(isopentyloxy)octylide...) Show SMILES CC(C)CCOCCCCCCC\C=C1/CC(CO)(COC(=O)C(C)(C)C)OC1=O Show InChI InChI=1S/C24H42O6/c1-19(2)13-15-28-14-11-9-7-6-8-10-12-20-16-24(17-25,30-21(20)26)18-29-22(27)23(3,4)5/h12,19,25H,6-11,13-18H2,1-5H3/b20-12+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Displacement of [20-3H]phorbol 12,13-dibutyrate from recombinant PKCalpha				Bioorg Med Chem Lett 20: 1008-12 (2010) Article DOI: 10.1016/j.bmcl.2009.12.058 BindingDB Entry DOI: 10.7270/Q29C6XJT
					More data for this Ligand-Target Pair
Protein kinase C alpha type (Homo sapiens (Human))	BDBM50310100 ((E)-(2-(hydroxymethyl)-5-oxo-4-tetradecylidenetetr...) Show SMILES CCCCCCCCCCCCC\C=C1/CC(CO)(COC(=O)C(C)(C)C)OC1=O Show InChI InChI=1S/C25H44O5/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-21-18-25(19-26,30-22(21)27)20-29-23(28)24(2,3)4/h17,26H,5-16,18-20H2,1-4H3/b21-17+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Displacement of [20-3H]phorbol 12,13-dibutyrate from recombinant PKCalpha				Bioorg Med Chem Lett 20: 1008-12 (2010) Article DOI: 10.1016/j.bmcl.2009.12.058 BindingDB Entry DOI: 10.7270/Q29C6XJT
					More data for this Ligand-Target Pair
Protein kinase C alpha type (Homo sapiens (Human))	BDBM50310125 ((E)-(4-(16-(formyloxy)hexadecylidene)-2-(hydroxyme...) Show SMILES CC(C)(C)C(=O)OCC1(CO)C\C(=C/CCCCCCCCCCCCCCCOC=O)C(=O)O1 Show InChI InChI=1S/C28H48O7/c1-27(2,3)26(32)34-22-28(21-29)20-24(25(31)35-28)18-16-14-12-10-8-6-4-5-7-9-11-13-15-17-19-33-23-30/h18,23,29H,4-17,19-22H2,1-3H3/b24-18+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Displacement of [20-3H]phorbol 12,13-dibutyrate from recombinant PKCalpha				Bioorg Med Chem Lett 20: 1008-12 (2010) Article DOI: 10.1016/j.bmcl.2009.12.058 BindingDB Entry DOI: 10.7270/Q29C6XJT
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50240692 (CHEMBL4078588) Show SMILES Cc1ccc(Cc2cc3c(ncn([C@H]4CCCC[C@@H]4O)c3=O)c3ccccc23)cn1 |r| Show InChI InChI=1S/C25H25N3O2/c1-16-10-11-17(14-26-16)12-18-13-21-24(20-7-3-2-6-19(18)20)27-15-28(25(21)30)22-8-4-5-9-23(22)29/h2-3,6-7,10-11,13-15,22-23,29H,4-5,8-9,12H2,1H3/t22-,23-/m0/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem	Article PubMed	8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]PT-1284 human muscarinic acetylcholine receptor M1 expressed in CHO cell membranes after 90 mins scintillation counting method				J Med Chem 60: 6649-6663 (2017) Article DOI: 10.1021/acs.jmedchem.7b00597 BindingDB Entry DOI: 10.7270/Q2ZK5JS0
					More data for this Ligand-Target Pair
Protein kinase C alpha type (Homo sapiens (Human))	BDBM50310106 ((E)-(2-(hydroxymethyl)-5-oxo-4-(8-(pentyloxy)octyl...) Show SMILES CCCCCOCCCCCCC\C=C1/CC(CO)(COC(=O)C(C)(C)C)OC1=O Show InChI InChI=1S/C24H42O6/c1-5-6-12-15-28-16-13-10-8-7-9-11-14-20-17-24(18-25,30-21(20)26)19-29-22(27)23(2,3)4/h14,25H,5-13,15-19H2,1-4H3/b20-14+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Displacement of [20-3H]phorbol 12,13-dibutyrate from recombinant PKCalpha				Bioorg Med Chem Lett 20: 1008-12 (2010) Article DOI: 10.1016/j.bmcl.2009.12.058 BindingDB Entry DOI: 10.7270/Q29C6XJT
					More data for this Ligand-Target Pair
Protein kinase C alpha type (Homo sapiens (Human))	BDBM50310103 ((E)-(2-(hydroxymethyl)-4-(12-methoxydodecylidene)-...) Show SMILES COCCCCCCCCCCC\C=C1/CC(CO)(COC(=O)C(C)(C)C)OC1=O Show InChI InChI=1S/C24H42O6/c1-23(2,3)22(27)29-19-24(18-25)17-20(21(26)30-24)15-13-11-9-7-5-6-8-10-12-14-16-28-4/h15,25H,5-14,16-19H2,1-4H3/b20-15+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Displacement of [20-3H]phorbol 12,13-dibutyrate from recombinant PKCalpha				Bioorg Med Chem Lett 20: 1008-12 (2010) Article DOI: 10.1016/j.bmcl.2009.12.058 BindingDB Entry DOI: 10.7270/Q29C6XJT
					More data for this Ligand-Target Pair
Protein kinase C alpha type (Homo sapiens (Human))	BDBM50310116 ((Z)-(4-(16-hydroxyhexadecylidene)-2-(hydroxymethyl...) Show SMILES CC(C)(C)C(=O)OCC1(CO)C\C(=C\CCCCCCCCCCCCCCCO)C(=O)O1 Show InChI InChI=1S/C27H48O6/c1-26(2,3)25(31)32-22-27(21-29)20-23(24(30)33-27)18-16-14-12-10-8-6-4-5-7-9-11-13-15-17-19-28/h18,28-29H,4-17,19-22H2,1-3H3/b23-18-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Displacement of [20-3H]phorbol 12,13-dibutyrate from recombinant PKCalpha				Bioorg Med Chem Lett 20: 1008-12 (2010) Article DOI: 10.1016/j.bmcl.2009.12.058 BindingDB Entry DOI: 10.7270/Q29C6XJT
					More data for this Ligand-Target Pair
Protein kinase C alpha type (Homo sapiens (Human))	BDBM50310130 ((E)-(4-(16-acetamidohexadecylidene)-2-(hydroxymeth...) Show SMILES CC(=O)NCCCCCCCCCCCCCCC\C=C1/CC(CO)(COC(=O)C(C)(C)C)OC1=O Show InChI InChI=1S/C29H51NO6/c1-24(32)30-20-18-16-14-12-10-8-6-5-7-9-11-13-15-17-19-25-21-29(22-31,36-26(25)33)23-35-27(34)28(2,3)4/h19,31H,5-18,20-23H2,1-4H3,(H,30,32)/b25-19+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Displacement of [20-3H]phorbol 12,13-dibutyrate from recombinant PKCalpha				Bioorg Med Chem Lett 20: 1008-12 (2010) Article DOI: 10.1016/j.bmcl.2009.12.058 BindingDB Entry DOI: 10.7270/Q29C6XJT
					More data for this Ligand-Target Pair
Protein kinase C alpha type (Homo sapiens (Human))	BDBM50310126 ((E)-(4-(16-acetoxyhexadecylidene)-2-(hydroxymethyl...) Show SMILES CC(=O)OCCCCCCCCCCCCCCC\C=C1/CC(CO)(COC(=O)C(C)(C)C)OC1=O Show InChI InChI=1S/C29H50O7/c1-24(31)34-20-18-16-14-12-10-8-6-5-7-9-11-13-15-17-19-25-21-29(22-30,36-26(25)32)23-35-27(33)28(2,3)4/h19,30H,5-18,20-23H2,1-4H3/b25-19+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Displacement of [20-3H]phorbol 12,13-dibutyrate from recombinant PKCalpha				Bioorg Med Chem Lett 20: 1008-12 (2010) Article DOI: 10.1016/j.bmcl.2009.12.058 BindingDB Entry DOI: 10.7270/Q29C6XJT
					More data for this Ligand-Target Pair
Protein kinase C alpha type (Homo sapiens (Human))	BDBM50310111 ((E)-(4-(8-(cyclopentyloxy)octylidene)-2-(hydroxyme...) Show SMILES CC(C)(C)C(=O)OCC1(CO)C\C(=C/CCCCCCCOC2CCCC2)C(=O)O1 Show InChI InChI=1S/C24H40O6/c1-23(2,3)22(27)29-18-24(17-25)16-19(21(26)30-24)12-8-6-4-5-7-11-15-28-20-13-9-10-14-20/h12,20,25H,4-11,13-18H2,1-3H3/b19-12+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Displacement of [20-3H]phorbol 12,13-dibutyrate from recombinant PKCalpha				Bioorg Med Chem Lett 20: 1008-12 (2010) Article DOI: 10.1016/j.bmcl.2009.12.058 BindingDB Entry DOI: 10.7270/Q29C6XJT
					More data for this Ligand-Target Pair
Amyloid-beta precursor protein (Homo sapiens (Human))	BDBM50122785 (4-(6-bromoH-imidazo[1,2-a]pyridin-2-yl)-N,N-dimeth...) Show SMILES CN(C)c1ccc(cc1)-c1cn2cc(Br)ccc2n1 Show InChI InChI=1S/C15H14BrN3/c1-18(2)13-6-3-11(4-7-13)14-10-19-9-12(16)5-8-15(19)17-14/h3-10H,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	10.3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Inhibition constant against [125I]-7 (TZDM) binding to Amyloid beta 1-40 aggregates				J Med Chem 46: 237-43 (2003) Article DOI: 10.1021/jm020351j BindingDB Entry DOI: 10.7270/Q2WH2PBC
					More data for this Ligand-Target Pair
Protein kinase C alpha type (Homo sapiens (Human))	BDBM50310121 ((Z)-(2-(hydroxymethyl)-5-oxo-4-(16-oxohexadecylide...) Show SMILES CC(C)(C)C(=O)OCC1(CO)C\C(=C\CCCCCCCCCCCCCCC=O)C(=O)O1 Show InChI InChI=1S/C27H46O6/c1-26(2,3)25(31)32-22-27(21-29)20-23(24(30)33-27)18-16-14-12-10-8-6-4-5-7-9-11-13-15-17-19-28/h18-19,29H,4-17,20-22H2,1-3H3/b23-18-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Displacement of [20-3H]phorbol 12,13-dibutyrate from recombinant PKCalpha				Bioorg Med Chem Lett 20: 1008-12 (2010) Article DOI: 10.1016/j.bmcl.2009.12.058 BindingDB Entry DOI: 10.7270/Q29C6XJT
					More data for this Ligand-Target Pair
Protein kinase C alpha type (Homo sapiens (Human))	BDBM50310127 ((E)-16-(5-(hydroxymethyl)-2-oxo-5-(pivaloyloxymeth...) Show SMILES CC(C)(C)C(=O)OCCCCCCCCCCCCCCC\C=C1/CC(CO)(COC(=O)C(C)(C)C)OC1=O Show InChI InChI=1S/C32H56O7/c1-30(2,3)28(35)37-22-20-18-16-14-12-10-8-7-9-11-13-15-17-19-21-26-23-32(24-33,39-27(26)34)25-38-29(36)31(4,5)6/h21,33H,7-20,22-25H2,1-6H3/b26-21+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Displacement of [20-3H]phorbol 12,13-dibutyrate from recombinant PKCalpha				Bioorg Med Chem Lett 20: 1008-12 (2010) Article DOI: 10.1016/j.bmcl.2009.12.058 BindingDB Entry DOI: 10.7270/Q29C6XJT
					More data for this Ligand-Target Pair
Protein kinase C alpha type (Homo sapiens (Human))	BDBM50310114 ((E)-(4-(12-hydroxydodecylidene)-2-(hydroxymethyl)-...) Show SMILES CC(C)(C)C(=O)OCC1(CO)C\C(=C/CCCCCCCCCCCO)C(=O)O1 Show InChI InChI=1S/C23H40O6/c1-22(2,3)21(27)28-18-23(17-25)16-19(20(26)29-23)14-12-10-8-6-4-5-7-9-11-13-15-24/h14,24-25H,4-13,15-18H2,1-3H3/b19-14+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Displacement of [20-3H]phorbol 12,13-dibutyrate from recombinant PKCalpha				Bioorg Med Chem Lett 20: 1008-12 (2010) Article DOI: 10.1016/j.bmcl.2009.12.058 BindingDB Entry DOI: 10.7270/Q29C6XJT
					More data for this Ligand-Target Pair
Amyloid-beta precursor protein (Homo sapiens (Human))	BDBM50122787 (2-(4'-dimethylaminophenyl)-6-iodoimidazo[1,2-a]pyr...) Show SMILES CN(C)c1ccc(cc1)-c1cn2cc(I)ccc2n1 Show InChI InChI=1S/C15H14IN3/c1-18(2)13-6-3-11(4-7-13)14-10-19-9-12(16)5-8-15(19)17-14/h3-10H,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Inhibition constant against [125I]-7 (TZDM) binding to Amyloid beta 1-40 aggregates				J Med Chem 46: 237-43 (2003) Article DOI: 10.1021/jm020351j BindingDB Entry DOI: 10.7270/Q2WH2PBC
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50240694 (CHEMBL4067722) Show SMILES Cc1cc2CN([C@H]3CCOC[C@@H]3O)C(=O)c2cc1Cc1ccc(cc1)-c1cocn1 |r| Show InChI InChI=1S/C24H24N2O4/c1-15-8-19-11-26(22-6-7-29-13-23(22)27)24(28)20(19)10-18(15)9-16-2-4-17(5-3-16)21-12-30-14-25-21/h2-5,8,10,12,14,22-23,27H,6-7,9,11,13H2,1H3/t22-,23-/m0/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]PT-1284 human muscarinic acetylcholine receptor M1 expressed in CHO cell membranes after 90 mins scintillation counting method				J Med Chem 60: 6649-6663 (2017) Article DOI: 10.1021/acs.jmedchem.7b00597 BindingDB Entry DOI: 10.7270/Q2ZK5JS0
					More data for this Ligand-Target Pair
Protein kinase C alpha type (Homo sapiens (Human))	BDBM50310128 ((E)-(4-(16-azidohexadecylidene)-2-(hydroxymethyl)-...) Show SMILES CC(C)(C)C(=O)OCC1(CO)C\C(=C/CCCCCCCCCCCCCCCN=[N+]=[N-])C(=O)O1 Show InChI InChI=1S/C27H47N3O5/c1-26(2,3)25(33)34-22-27(21-31)20-23(24(32)35-27)18-16-14-12-10-8-6-4-5-7-9-11-13-15-17-19-29-30-28/h18,31H,4-17,19-22H2,1-3H3/b23-18+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Displacement of [20-3H]phorbol 12,13-dibutyrate from recombinant PKCalpha				Bioorg Med Chem Lett 20: 1008-12 (2010) Article DOI: 10.1016/j.bmcl.2009.12.058 BindingDB Entry DOI: 10.7270/Q29C6XJT
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50240693 (CHEMBL4097569) Show SMILES Cc1cnc(cc1Cc1ccc(cc1)-c1cscn1)C(=O)N[C@H]1CCOC[C@@H]1O |r| Show InChI InChI=1S/C22H23N3O3S/c1-14-10-23-19(22(27)25-18-6-7-28-11-21(18)26)9-17(14)8-15-2-4-16(5-3-15)20-12-29-13-24-20/h2-5,9-10,12-13,18,21,26H,6-8,11H2,1H3,(H,25,27)/t18-,21-/m0/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	19	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Displacement of [3H]PT-1284 human muscarinic acetylcholine receptor M1 expressed in CHO cell membranes after 90 mins scintillation counting method				J Med Chem 60: 6649-6663 (2017) Article DOI: 10.1021/acs.jmedchem.7b00597 BindingDB Entry DOI: 10.7270/Q2ZK5JS0
					More data for this Ligand-Target Pair
Protein kinase C alpha type (Homo sapiens (Human))	BDBM50310122 ((E)-16-(5-(hydroxymethyl)-2-oxo-5-(pivaloyloxymeth...) Show SMILES CC(C)(C)C(=O)OCC1(CO)C\C(=C/CCCCCCCCCCCCCCC(O)=O)C(=O)O1 Show InChI InChI=1S/C27H46O7/c1-26(2,3)25(32)33-21-27(20-28)19-22(24(31)34-27)17-15-13-11-9-7-5-4-6-8-10-12-14-16-18-23(29)30/h17,28H,4-16,18-21H2,1-3H3,(H,29,30)/b22-17+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Displacement of [20-3H]phorbol 12,13-dibutyrate from recombinant PKCalpha				Bioorg Med Chem Lett 20: 1008-12 (2010) Article DOI: 10.1016/j.bmcl.2009.12.058 BindingDB Entry DOI: 10.7270/Q29C6XJT
					More data for this Ligand-Target Pair
Protein kinase C alpha type (Homo sapiens (Human))	BDBM50310119 ((E)-(2-(hydroxymethyl)-5-oxo-4-(12-oxododecylidene...) Show SMILES CC(C)(C)C(=O)OCC1(CO)C\C(=C/CCCCCCCCCCC=O)C(=O)O1 Show InChI InChI=1S/C23H38O6/c1-22(2,3)21(27)28-18-23(17-25)16-19(20(26)29-23)14-12-10-8-6-4-5-7-9-11-13-15-24/h14-15,25H,4-13,16-18H2,1-3H3/b19-14+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Displacement of [20-3H]phorbol 12,13-dibutyrate from recombinant PKCalpha				Bioorg Med Chem Lett 20: 1008-12 (2010) Article DOI: 10.1016/j.bmcl.2009.12.058 BindingDB Entry DOI: 10.7270/Q29C6XJT
					More data for this Ligand-Target Pair
Protein kinase C alpha type (Homo sapiens (Human))	BDBM50310129 ((E)-(4-(16-aminohexadecylidene)-2-(hydroxymethyl)-...) Show SMILES CC(C)(C)C(=O)OCC1(CO)C\C(=C/CCCCCCCCCCCCCCCN)C(=O)O1 Show InChI InChI=1S/C27H49NO5/c1-26(2,3)25(31)32-22-27(21-29)20-23(24(30)33-27)18-16-14-12-10-8-6-4-5-7-9-11-13-15-17-19-28/h18,29H,4-17,19-22,28H2,1-3H3/b23-18+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	36	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Displacement of [20-3H]phorbol 12,13-dibutyrate from recombinant PKCalpha				Bioorg Med Chem Lett 20: 1008-12 (2010) Article DOI: 10.1016/j.bmcl.2009.12.058 BindingDB Entry DOI: 10.7270/Q29C6XJT
					More data for this Ligand-Target Pair
Protein kinase C alpha type (Homo sapiens (Human))	BDBM50310118 ((E)-(2-(hydroxymethyl)-5-oxo-4-(8-oxooctylidene)te...) Show SMILES CC(C)(C)C(=O)OCC1(CO)C\C(=C/CCCCCCC=O)C(=O)O1 Show InChI InChI=1S/C19H30O6/c1-18(2,3)17(23)24-14-19(13-21)12-15(16(22)25-19)10-8-6-4-5-7-9-11-20/h10-11,21H,4-9,12-14H2,1-3H3/b15-10+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	39	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Displacement of [20-3H]phorbol 12,13-dibutyrate from recombinant PKCalpha				Bioorg Med Chem Lett 20: 1008-12 (2010) Article DOI: 10.1016/j.bmcl.2009.12.058 BindingDB Entry DOI: 10.7270/Q29C6XJT
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor M1 (Homo sapiens (Human))	BDBM50135213 (CHEMBL3747016) Show SMILES Cn1ccc(n1)-c1ccc(Cn2cc(C(=O)N[C@H]3CCOC[C@@H]3O)c3ncccc23)cc1 |r| Show InChI InChI=1S/C24H25N5O3/c1-28-11-8-19(27-28)17-6-4-16(5-7-17)13-29-14-18(23-21(29)3-2-10-25-23)24(31)26-20-9-12-32-15-22(20)30/h2-8,10-11,14,20,22,30H,9,12-13,15H2,1H3,(H,26,31)/t20-,22-/m0/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description In vitro inhibitory activity against [3H]- (+)-3-PPP binding to Sigma opioid receptor in guinea pig brain membrane homogenates				J Med Chem 60: 6649-6663 (2017) Article DOI: 10.1021/acs.jmedchem.7b00597 BindingDB Entry DOI: 10.7270/Q2ZK5JS0
					More data for this Ligand-Target Pair
Protein kinase C alpha type (Homo sapiens (Human))	BDBM50310117 ((E)-(4-(8-hydroxyhexadecylidene)-2-(hydroxymethyl)...) Show SMILES CCCCCCCCC(O)CCCCCC\C=C1/CC(CO)(COC(=O)C(C)(C)C)OC1=O Show InChI InChI=1S/C27H48O6/c1-5-6-7-8-11-14-17-23(29)18-15-12-9-10-13-16-22-19-27(20-28,33-24(22)30)21-32-25(31)26(2,3)4/h16,23,28-29H,5-15,17-21H2,1-4H3/b22-16+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	118	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Displacement of [20-3H]phorbol 12,13-dibutyrate from recombinant PKCalpha				Bioorg Med Chem Lett 20: 1008-12 (2010) Article DOI: 10.1016/j.bmcl.2009.12.058 BindingDB Entry DOI: 10.7270/Q29C6XJT
					More data for this Ligand-Target Pair
Protein kinase C alpha type (Homo sapiens (Human))	BDBM50310102 ((E)-(2-(hydroxymethyl)-4-(8-methoxyoctylidene)-5-o...) Show SMILES COCCCCCCC\C=C1/CC(CO)(COC(=O)C(C)(C)C)OC1=O Show InChI InChI=1S/C20H34O6/c1-19(2,3)18(23)25-15-20(14-21)13-16(17(22)26-20)11-9-7-5-6-8-10-12-24-4/h11,21H,5-10,12-15H2,1-4H3/b16-11+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	191	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Displacement of [20-3H]phorbol 12,13-dibutyrate from recombinant PKCalpha				Bioorg Med Chem Lett 20: 1008-12 (2010) Article DOI: 10.1016/j.bmcl.2009.12.058 BindingDB Entry DOI: 10.7270/Q29C6XJT
					More data for this Ligand-Target Pair
Protein kinase C alpha type (Homo sapiens (Human))	BDBM50310108 ((E)-(2-(hydroxymethyl)-4-(8-(methoxymethoxy)octyli...) Show SMILES COCOCCCCCCC\C=C1/CC(CO)(COC(=O)C(C)(C)C)OC1=O Show InChI InChI=1S/C21H36O7/c1-20(2,3)19(24)27-15-21(14-22)13-17(18(23)28-21)11-9-7-5-6-8-10-12-26-16-25-4/h11,22H,5-10,12-16H2,1-4H3/b17-11+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	198	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Displacement of [20-3H]phorbol 12,13-dibutyrate from recombinant PKCalpha				Bioorg Med Chem Lett 20: 1008-12 (2010) Article DOI: 10.1016/j.bmcl.2009.12.058 BindingDB Entry DOI: 10.7270/Q29C6XJT
					More data for this Ligand-Target Pair
Amyloid-beta precursor protein (Homo sapiens (Human))	BDBM50122784 (CHEMBL78621 | Dimethyl-[4-(6-methyl-imidazo[1,2-a]...) Show SMILES CN(C)c1ccc(cc1)-c1cn2cc(C)ccc2n1 Show InChI InChI=1S/C16H17N3/c1-12-4-9-16-17-15(11-19(16)10-12)13-5-7-14(8-6-13)18(2)3/h4-11H,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	242	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Inhibition constant against [125I]-7 (TZDM) binding to Amyloid beta 1-40 aggregates				J Med Chem 46: 237-43 (2003) Article DOI: 10.1021/jm020351j BindingDB Entry DOI: 10.7270/Q2WH2PBC
					More data for this Ligand-Target Pair
Protein kinase C alpha type (Homo sapiens (Human))	BDBM50310109 ((E)-(2-(hydroxymethyl)-4-(8-((2-methoxyethoxy)meth...) Show SMILES COCCOCOCCCCCCC\C=C1/CC(CO)(COC(=O)C(C)(C)C)OC1=O Show InChI InChI=1S/C23H40O8/c1-22(2,3)21(26)30-17-23(16-24)15-19(20(25)31-23)11-9-7-5-6-8-10-12-28-18-29-14-13-27-4/h11,24H,5-10,12-18H2,1-4H3/b19-11+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	323	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Displacement of [20-3H]phorbol 12,13-dibutyrate from recombinant PKCalpha				Bioorg Med Chem Lett 20: 1008-12 (2010) Article DOI: 10.1016/j.bmcl.2009.12.058 BindingDB Entry DOI: 10.7270/Q29C6XJT
					More data for this Ligand-Target Pair
Amyloid-beta precursor protein (Homo sapiens (Human))	BDBM50122789 (CHEMBL309920 | [2-(4-Bromo-phenyl)-imidazo[1,2-a]p...) Show SMILES CN(C)c1ccc2nc(cn2c1)-c1ccc(Br)cc1 Show InChI InChI=1S/C15H14BrN3/c1-18(2)13-7-8-15-17-14(10-19(15)9-13)11-3-5-12(16)6-4-11/h3-10H,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	339	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Inhibition constant against [125I]-7 (TZDM) binding to Amyloid beta 1-40 aggregates				J Med Chem 46: 237-43 (2003) Article DOI: 10.1021/jm020351j BindingDB Entry DOI: 10.7270/Q2WH2PBC
					More data for this Ligand-Target Pair
Protein kinase C alpha type (Homo sapiens (Human))	BDBM50310113 ((E)-(2-(hydroxymethyl)-4-(8-hydroxyoctylidene)-5-o...) Show SMILES CC(C)(C)C(=O)OCC1(CO)C\C(=C/CCCCCCCO)C(=O)O1 Show InChI InChI=1S/C19H32O6/c1-18(2,3)17(23)24-14-19(13-21)12-15(16(22)25-19)10-8-6-4-5-7-9-11-20/h10,20-21H,4-9,11-14H2,1-3H3/b15-10+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	378	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Displacement of [20-3H]phorbol 12,13-dibutyrate from recombinant PKCalpha				Bioorg Med Chem Lett 20: 1008-12 (2010) Article DOI: 10.1016/j.bmcl.2009.12.058 BindingDB Entry DOI: 10.7270/Q29C6XJT
					More data for this Ligand-Target Pair
Protein kinase C alpha type (Homo sapiens (Human))	BDBM50310123 ((E)-methyl 8-(5-(hydroxymethyl)-2-oxo-5-(pivaloylo...) Show SMILES COC(=O)CCCCCC\C=C1/CC(CO)(COC(=O)C(C)(C)C)OC1=O Show InChI InChI=1S/C20H32O7/c1-19(2,3)18(24)26-14-20(13-21)12-15(17(23)27-20)10-8-6-5-7-9-11-16(22)25-4/h10,21H,5-9,11-14H2,1-4H3/b15-10+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	533	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Displacement of [20-3H]phorbol 12,13-dibutyrate from recombinant PKCalpha				Bioorg Med Chem Lett 20: 1008-12 (2010) Article DOI: 10.1016/j.bmcl.2009.12.058 BindingDB Entry DOI: 10.7270/Q29C6XJT
					More data for this Ligand-Target Pair
Amyloid-beta precursor protein (Homo sapiens (Human))	BDBM50122788 (2-(4-Bromo-phenyl)-6-methyl-imidazo[1,2-a]pyridine...) Show SMILES Cc1ccc2nc(cn2c1)-c1ccc(Br)cc1 Show InChI InChI=1S/C14H11BrN2/c1-10-2-7-14-16-13(9-17(14)8-10)11-3-5-12(15)6-4-11/h2-9H,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	638	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Inhibition constant against [125I]-7 (TZDM) binding to Amyloid beta 1-40 aggregates				J Med Chem 46: 237-43 (2003) Article DOI: 10.1021/jm020351j BindingDB Entry DOI: 10.7270/Q2WH2PBC
					More data for this Ligand-Target Pair
Amyloid-beta precursor protein (Homo sapiens (Human))	BDBM50122782 ((4-Imidazo[1,2-a]pyridin-2-yl-phenyl)-methyl-amine...) Show SMILES CNc1ccc(cc1)-c1cn2ccccc2n1 Show InChI InChI=1S/C14H13N3/c1-15-12-7-5-11(6-8-12)13-10-17-9-3-2-4-14(17)16-13/h2-10,15H,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Inhibition constant against [125I]-7 (TZDM) binding to Amyloid beta 1-40 aggregates				J Med Chem 46: 237-43 (2003) Article DOI: 10.1021/jm020351j BindingDB Entry DOI: 10.7270/Q2WH2PBC
					More data for this Ligand-Target Pair
Amyloid-beta precursor protein (Homo sapiens (Human))	BDBM26193 (2-Hydroxybenzoate, I | 2-hydroxybenzoic acid | CHE...) Show SMILES OC(=O)c1ccccc1O Show InChI InChI=1S/C7H6O3/c8-6-4-2-1-3-5(6)7(9)10/h1-4,8H,(H,9,10)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	>1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Inhibitory activity against binding of [125I]-IMSB to amyloid beta in brain				J Med Chem 44: 2270-5 (2001) BindingDB Entry DOI: 10.7270/Q22J6B4Z
					More data for this Ligand-Target Pair

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