Compile Data Set for Download or QSAR

Found 169 hits with Last Name = 'cooper' and Initial = 'dg'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50222900 (CHEMBL267062) Show SMILES O=C1N(CCN2CCC(CC2)c2c[nH]c3ccccc23)CCCc2ccccc12 Show InChI InChI=1S/C25H29N3O/c29-25-21-8-2-1-6-19(21)7-5-13-28(25)17-16-27-14-11-20(12-15-27)23-18-26-24-10-4-3-9-22(23)24/h1-4,6,8-10,18,20,26H,5,7,11-17H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.407	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Binding affinity at human cloned 5-hydroxytryptamine 7 receptor.				Bioorg Med Chem Lett 13: 1055-8 (2003) BindingDB Entry DOI: 10.7270/Q2X066D4
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50222781 (CHEMBL9951) Show SMILES Fc1ccc2n(ccc2c1)C1CCN(CCN2CCCc3ccccc3C2=O)CC1 Show InChI InChI=1S/C25H28FN3O/c26-21-7-8-24-20(18-21)9-15-29(24)22-10-13-27(14-11-22)16-17-28-12-3-5-19-4-1-2-6-23(19)25(28)30/h1-2,4,6-9,15,18,22H,3,5,10-14,16-17H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	0.562	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Binding affinity at human cloned 5-hydroxytryptamine 7 receptor.				Bioorg Med Chem Lett 13: 1055-8 (2003) BindingDB Entry DOI: 10.7270/Q2X066D4
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50222777 (CHEMBL9616) Show SMILES Fc1ccc(cc1)C(=O)C1CCN(CCN2CCCc3ccccc3C2=O)CC1 Show InChI InChI=1S/C24H27FN2O2/c25-21-9-7-19(8-10-21)23(28)20-11-14-26(15-12-20)16-17-27-13-3-5-18-4-1-2-6-22(18)24(27)29/h1-2,4,6-10,20H,3,5,11-17H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	1.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Binding affinity at human cloned 5-hydroxytryptamine 7 receptor.				Bioorg Med Chem Lett 13: 1055-8 (2003) BindingDB Entry DOI: 10.7270/Q2X066D4
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50222900 (CHEMBL267062) Show SMILES O=C1N(CCN2CCC(CC2)c2c[nH]c3ccccc23)CCCc2ccccc12 Show InChI InChI=1S/C25H29N3O/c29-25-21-8-2-1-6-19(21)7-5-13-28(25)17-16-27-14-11-20(12-15-27)23-18-26-24-10-4-3-9-22(23)24/h1-4,6,8-10,18,20,26H,5,7,11-17H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Binding affinity at human cloned 5-hydroxytryptamine 2A receptor.				Bioorg Med Chem Lett 13: 1055-8 (2003) BindingDB Entry DOI: 10.7270/Q2X066D4
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50222899 (CHEMBL9347) Show SMILES Fc1ccc2n(nnc2c1)C1CCN(CCN2CCCc3ccccc3C2=O)CC1 Show InChI InChI=1S/C23H26FN5O/c24-18-7-8-22-21(16-18)25-26-29(22)19-9-12-27(13-10-19)14-15-28-11-3-5-17-4-1-2-6-20(17)23(28)30/h1-2,4,6-8,16,19H,3,5,9-15H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Binding affinity at human cloned 5-hydroxytryptamine 7 receptor.				Bioorg Med Chem Lett 13: 1055-8 (2003) BindingDB Entry DOI: 10.7270/Q2X066D4
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50125260 (2-{2-[4-(5-Fluoro-2-oxo-2,3-dihydro-benzoimidazol-...) Show SMILES Fc1ccc2n(C3CCN(CCN4CCCc5ccccc5C4=O)CC3)c(=O)[nH]c2c1 Show InChI InChI=1S/C24H27FN4O2/c25-18-7-8-22-21(16-18)26-24(31)29(22)19-9-12-27(13-10-19)14-15-28-11-3-5-17-4-1-2-6-20(17)23(28)30/h1-2,4,6-8,16,19H,3,5,9-15H2,(H,26,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	2.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Binding affinity at human cloned 5-hydroxytryptamine 7 receptor.				Bioorg Med Chem Lett 13: 1055-8 (2003) BindingDB Entry DOI: 10.7270/Q2X066D4
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50222780 (CHEMBL275343) Show SMILES Clc1ccc(cc1)C(=O)C1CCN(CCN2CCCc3ccccc3C2=O)CC1 Show InChI InChI=1S/C24H27ClN2O2/c25-21-9-7-19(8-10-21)23(28)20-11-14-26(15-12-20)16-17-27-13-3-5-18-4-1-2-6-22(18)24(27)29/h1-2,4,6-10,20H,3,5,11-17H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	2.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Binding affinity at human cloned 5-hydroxytryptamine 7 receptor.				Bioorg Med Chem Lett 13: 1055-8 (2003) BindingDB Entry DOI: 10.7270/Q2X066D4
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50222894 (CHEMBL9952) Show SMILES O=C1N(CCN2CCC(CC2)n2ccc3ccccc23)CCCc2ccccc12 Show InChI InChI=1S/C25H29N3O/c29-25-23-9-3-1-6-20(23)8-5-14-27(25)19-18-26-15-12-22(13-16-26)28-17-11-21-7-2-4-10-24(21)28/h1-4,6-7,9-11,17,22H,5,8,12-16,18-19H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Binding affinity at human cloned 5-hydroxytryptamine 7 receptor.				Bioorg Med Chem Lett 13: 1055-8 (2003) BindingDB Entry DOI: 10.7270/Q2X066D4
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1F (Homo sapiens (Human))	BDBM50091438 ((E)-3-(3,4-Dichloro-phenyl)-N-{5-[4-(5-hydroxy-1H-...) Show SMILES Oc1ccc2[nH]cc(C3CCN(CCCCCNC(=O)\C=C\c4ccc(Cl)c(Cl)c4)CC3)c2c1 Show InChI InChI=1S/C27H31Cl2N3O2/c28-24-7-4-19(16-25(24)29)5-9-27(34)30-12-2-1-3-13-32-14-10-20(11-15-32)23-18-31-26-8-6-21(33)17-22(23)26/h4-9,16-18,20,31,33H,1-3,10-15H2,(H,30,34)/b9-5+	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	3.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity for 5-hydroxytryptamine 1F receptor was determined				Bioorg Med Chem Lett 11: 2177-80 (2001) BindingDB Entry DOI: 10.7270/Q2BP023S
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50470855 (CHEMBL60708) Show SMILES COc1cc2ccccc2cc1C(=O)NC1CCN(Cc2ccccc2)C1 Show InChI InChI=1S/C23H24N2O2/c1-27-22-14-19-10-6-5-9-18(19)13-21(22)23(26)24-20-11-12-25(16-20)15-17-7-3-2-4-8-17/h2-10,13-14,20H,11-12,15-16H2,1H3,(H,24,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Ltd Curated by ChEMBL					Assay Description Binding affinity against cloned human Dopamine receptor D4 using [3H]nemonapride as radioligand				J Med Chem 39: 1946-8 (1996) Article DOI: 10.1021/jm960017l BindingDB Entry DOI: 10.7270/Q2R49THW
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50222778 (CHEMBL275451) Show SMILES Fc1ccc(OC2CCN(CCN3CCCc4ccccc4C3=O)CC2)cc1 Show InChI InChI=1S/C23H27FN2O2/c24-19-7-9-20(10-8-19)28-21-11-14-25(15-12-21)16-17-26-13-3-5-18-4-1-2-6-22(18)23(26)27/h1-2,4,6-10,21H,3,5,11-17H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	4.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Binding affinity at human cloned 5-hydroxytryptamine 7 receptor.				Bioorg Med Chem Lett 13: 1055-8 (2003) BindingDB Entry DOI: 10.7270/Q2X066D4
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50470850 (CHEMBL59326) Show SMILES COc1cc2ccccc2cc1C(=O)OCC1CCN(Cc2ccccc2)CC1 Show InChI InChI=1S/C25H27NO3/c1-28-24-16-22-10-6-5-9-21(22)15-23(24)25(27)29-18-20-11-13-26(14-12-20)17-19-7-3-2-4-8-19/h2-10,15-16,20H,11-14,17-18H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Ltd Curated by ChEMBL					Assay Description Binding affinity against cloned human Dopamine receptor D4 using [3H]nemonapride as radioligand				J Med Chem 39: 1946-8 (1996) Article DOI: 10.1021/jm960017l BindingDB Entry DOI: 10.7270/Q2R49THW
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1E (Homo sapiens (Human))	BDBM50091438 ((E)-3-(3,4-Dichloro-phenyl)-N-{5-[4-(5-hydroxy-1H-...) Show SMILES Oc1ccc2[nH]cc(C3CCN(CCCCCNC(=O)\C=C\c4ccc(Cl)c(Cl)c4)CC3)c2c1 Show InChI InChI=1S/C27H31Cl2N3O2/c28-24-7-4-19(16-25(24)29)5-9-27(34)30-12-2-1-3-13-32-14-10-20(11-15-32)23-18-31-26-8-6-21(33)17-22(23)26/h4-9,16-18,20,31,33H,1-3,10-15H2,(H,30,34)/b9-5+	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	6.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity for 5-hydroxytryptamine 1E receptor was determined				Bioorg Med Chem Lett 11: 2177-80 (2001) BindingDB Entry DOI: 10.7270/Q2BP023S
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50470854 (CHEMBL433255) Show SMILES COc1cc2ccccc2cc1OC(=O)CC1CCN(Cc2ccccc2)CC1 Show InChI InChI=1S/C25H27NO3/c1-28-23-16-21-9-5-6-10-22(21)17-24(23)29-25(27)15-19-11-13-26(14-12-19)18-20-7-3-2-4-8-20/h2-10,16-17,19H,11-15,18H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	6.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Ltd Curated by ChEMBL					Assay Description Binding affinity against cloned human Dopamine receptor D4 using [3H]nemonapride as radioligand				J Med Chem 39: 1946-8 (1996) Article DOI: 10.1021/jm960017l BindingDB Entry DOI: 10.7270/Q2R49THW
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50222897 (CHEMBL9446) Show SMILES Fc1ccc2N(C3CCN(CCN4CCCc5ccccc5C4=O)CC3)C(=O)Cc2c1 Show InChI InChI=1S/C25H28FN3O2/c26-20-7-8-23-19(16-20)17-24(30)29(23)21-9-12-27(13-10-21)14-15-28-11-3-5-18-4-1-2-6-22(18)25(28)31/h1-2,4,6-8,16,21H,3,5,9-15,17H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	6.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Binding affinity at human cloned 5-hydroxytryptamine 7 receptor.				Bioorg Med Chem Lett 13: 1055-8 (2003) BindingDB Entry DOI: 10.7270/Q2X066D4
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50222781 (CHEMBL9951) Show SMILES Fc1ccc2n(ccc2c1)C1CCN(CCN2CCCc3ccccc3C2=O)CC1 Show InChI InChI=1S/C25H28FN3O/c26-21-7-8-24-20(18-21)9-15-29(24)22-10-13-27(14-11-22)16-17-28-12-3-5-19-4-1-2-6-23(19)25(28)30/h1-2,4,6-9,15,18,22H,3,5,10-14,16-17H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	6.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Binding affinity at human cloned 5-hydroxytryptamine 2A receptor.				Bioorg Med Chem Lett 13: 1055-8 (2003) BindingDB Entry DOI: 10.7270/Q2X066D4
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50091438 ((E)-3-(3,4-Dichloro-phenyl)-N-{5-[4-(5-hydroxy-1H-...) Show SMILES Oc1ccc2[nH]cc(C3CCN(CCCCCNC(=O)\C=C\c4ccc(Cl)c(Cl)c4)CC3)c2c1 Show InChI InChI=1S/C27H31Cl2N3O2/c28-24-7-4-19(16-25(24)29)5-9-27(34)30-12-2-1-3-13-32-14-10-20(11-15-32)23-18-31-26-8-6-21(33)17-22(23)26/h4-9,16-18,20,31,33H,1-3,10-15H2,(H,30,34)/b9-5+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	7.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity for Dopamine receptor D3 was determined				Bioorg Med Chem Lett 11: 2177-80 (2001) BindingDB Entry DOI: 10.7270/Q2BP023S
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50222782 (CHEMBL9770) Show SMILES Cc1ccc(OC2CCN(CCN3CCCc4ccccc4C3=O)CC2)cc1 Show InChI InChI=1S/C24H30N2O2/c1-19-8-10-21(11-9-19)28-22-12-15-25(16-13-22)17-18-26-14-4-6-20-5-2-3-7-23(20)24(26)27/h2-3,5,7-11,22H,4,6,12-18H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	9.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Binding affinity at human cloned 5-hydroxytryptamine 7 receptor.				Bioorg Med Chem Lett 13: 1055-8 (2003) BindingDB Entry DOI: 10.7270/Q2X066D4
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50222893 (CHEMBL9250) Show SMILES Fc1ccc2n(C3CCN(CCN4CCCc5ccccc5C4=O)CC3)c(=O)oc2c1 Show InChI InChI=1S/C24H26FN3O3/c25-18-7-8-21-22(16-18)31-24(30)28(21)19-9-12-26(13-10-19)14-15-27-11-3-5-17-4-1-2-6-20(17)23(27)29/h1-2,4,6-8,16,19H,3,5,9-15H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	9.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Binding affinity at human cloned 5-hydroxytryptamine 7 receptor.				Bioorg Med Chem Lett 13: 1055-8 (2003) BindingDB Entry DOI: 10.7270/Q2X066D4
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50222784 (CHEMBL273872) Show SMILES Oc1nc2ccccc2n1C1CCN(CCN2CCCc3ccccc3C2=O)CC1 Show InChI InChI=1S/C24H28N4O2/c29-23-20-8-2-1-6-18(20)7-5-13-27(23)17-16-26-14-11-19(12-15-26)28-22-10-4-3-9-21(22)25-24(28)30/h1-4,6,8-10,19H,5,7,11-17H2,(H,25,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Binding affinity at human cloned 5-hydroxytryptamine 7 receptor.				Bioorg Med Chem Lett 13: 1055-8 (2003) BindingDB Entry DOI: 10.7270/Q2X066D4
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50222779 (CHEMBL269400) Show SMILES Cc1ccccc1OC1CCN(CCC2CCCc3ccccc3C2=O)CC1 Show InChI InChI=1S/C25H31NO2/c1-19-7-2-5-12-24(19)28-22-14-17-26(18-15-22)16-13-21-10-6-9-20-8-3-4-11-23(20)25(21)27/h2-5,7-8,11-12,21-22H,6,9-10,13-18H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Binding affinity at human cloned 5-hydroxytryptamine 7 receptor.				Bioorg Med Chem Lett 13: 1055-8 (2003) BindingDB Entry DOI: 10.7270/Q2X066D4
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50222890 (CHEMBL9840) Show SMILES COc1ccccc1C1CCN(CC2CCc3ccccc3C(=O)C2)CC1 Show InChI InChI=1S/C24H29NO2/c1-27-24-9-5-4-8-22(24)20-12-14-25(15-13-20)17-18-10-11-19-6-2-3-7-21(19)23(26)16-18/h2-9,18,20H,10-17H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Binding affinity at human cloned 5-hydroxytryptamine 7 receptor.				Bioorg Med Chem Lett 13: 1055-8 (2003) BindingDB Entry DOI: 10.7270/Q2X066D4
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50222889 (CHEMBL429202) Show SMILES Clc1ccc(OC2CCN(CCN3CCCc4ccccc4C3=O)CC2)cc1 Show InChI InChI=1S/C23H27ClN2O2/c24-19-7-9-20(10-8-19)28-21-11-14-25(15-12-21)16-17-26-13-3-5-18-4-1-2-6-22(18)23(26)27/h1-2,4,6-10,21H,3,5,11-17H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Binding affinity at human cloned 5-hydroxytryptamine 7 receptor.				Bioorg Med Chem Lett 13: 1055-8 (2003) BindingDB Entry DOI: 10.7270/Q2X066D4
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1B (Homo sapiens (Human))	BDBM50091438 ((E)-3-(3,4-Dichloro-phenyl)-N-{5-[4-(5-hydroxy-1H-...) Show SMILES Oc1ccc2[nH]cc(C3CCN(CCCCCNC(=O)\C=C\c4ccc(Cl)c(Cl)c4)CC3)c2c1 Show InChI InChI=1S/C27H31Cl2N3O2/c28-24-7-4-19(16-25(24)29)5-9-27(34)30-12-2-1-3-13-32-14-10-20(11-15-32)23-18-31-26-8-6-21(33)17-22(23)26/h4-9,16-18,20,31,33H,1-3,10-15H2,(H,30,34)/b9-5+	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity for 5-hydroxytryptamine 1B receptor was determined				Bioorg Med Chem Lett 11: 2177-80 (2001) BindingDB Entry DOI: 10.7270/Q2BP023S
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50222896 (CHEMBL275475) Show SMILES O=C1N(CCN2CCC(CC2)n2nnc3ccccc23)CCCc2ccccc12 Show InChI InChI=1S/C23H27N5O/c29-23-20-8-2-1-6-18(20)7-5-13-27(23)17-16-26-14-11-19(12-15-26)28-22-10-4-3-9-21(22)24-25-28/h1-4,6,8-10,19H,5,7,11-17H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Binding affinity at human cloned 5-hydroxytryptamine 7 receptor.				Bioorg Med Chem Lett 13: 1055-8 (2003) BindingDB Entry DOI: 10.7270/Q2X066D4
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50091438 ((E)-3-(3,4-Dichloro-phenyl)-N-{5-[4-(5-hydroxy-1H-...) Show SMILES Oc1ccc2[nH]cc(C3CCN(CCCCCNC(=O)\C=C\c4ccc(Cl)c(Cl)c4)CC3)c2c1 Show InChI InChI=1S/C27H31Cl2N3O2/c28-24-7-4-19(16-25(24)29)5-9-27(34)30-12-2-1-3-13-32-14-10-20(11-15-32)23-18-31-26-8-6-21(33)17-22(23)26/h4-9,16-18,20,31,33H,1-3,10-15H2,(H,30,34)/b9-5+	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity for Dopamine receptor D2 was determined				Bioorg Med Chem Lett 11: 2177-80 (2001) BindingDB Entry DOI: 10.7270/Q2BP023S
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50222777 (CHEMBL9616) Show SMILES Fc1ccc(cc1)C(=O)C1CCN(CCN2CCCc3ccccc3C2=O)CC1 Show InChI InChI=1S/C24H27FN2O2/c25-21-9-7-19(8-10-21)23(28)20-11-14-26(15-12-20)16-17-27-13-3-5-18-4-1-2-6-22(18)24(27)29/h1-2,4,6-10,20H,3,5,11-17H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Binding affinity at human cloned 5-hydroxytryptamine 2A receptor.				Bioorg Med Chem Lett 13: 1055-8 (2003) BindingDB Entry DOI: 10.7270/Q2X066D4
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50222894 (CHEMBL9952) Show SMILES O=C1N(CCN2CCC(CC2)n2ccc3ccccc23)CCCc2ccccc12 Show InChI InChI=1S/C25H29N3O/c29-25-23-9-3-1-6-20(23)8-5-14-27(25)19-18-26-15-12-22(13-16-26)28-17-11-21-7-2-4-10-24(21)28/h1-4,6-7,9-11,17,22H,5,8,12-16,18-19H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	19	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Binding affinity at human cloned 5-hydroxytryptamine 2A receptor.				Bioorg Med Chem Lett 13: 1055-8 (2003) BindingDB Entry DOI: 10.7270/Q2X066D4
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50222783 (CHEMBL9696) Show SMILES O=C1CC(CN2CCC(CC2)Oc2ccccc2)CCc2ccccc12 Show InChI InChI=1S/C23H27NO2/c25-23-16-18(10-11-19-6-4-5-9-22(19)23)17-24-14-12-21(13-15-24)26-20-7-2-1-3-8-20/h1-9,18,21H,10-17H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	19	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Binding affinity at human cloned 5-hydroxytryptamine 7 receptor.				Bioorg Med Chem Lett 13: 1055-8 (2003) BindingDB Entry DOI: 10.7270/Q2X066D4
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50222895 (CHEMBL9564) Show SMILES O=C1N(CCN2CCC(CC2)Oc2ccccc2)CCCc2ccccc12 Show InChI InChI=1S/C23H28N2O2/c26-23-22-11-5-4-7-19(22)8-6-14-25(23)18-17-24-15-12-21(13-16-24)27-20-9-2-1-3-10-20/h1-5,7,9-11,21H,6,8,12-18H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Binding affinity at human cloned 5-hydroxytryptamine 7 receptor.				Bioorg Med Chem Lett 13: 1055-8 (2003) BindingDB Entry DOI: 10.7270/Q2X066D4
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50203469 (3-Methoxy-naphthalene-2-carboxylic acid (1-benzyl-...) Show SMILES COc1cc2ccccc2cc1C(=O)NCC1CCN(Cc2ccccc2)CC1 Show InChI InChI=1S/C25H28N2O2/c1-29-24-16-22-10-6-5-9-21(22)15-23(24)25(28)26-17-19-11-13-27(14-12-19)18-20-7-3-2-4-8-20/h2-10,15-16,19H,11-14,17-18H2,1H3,(H,26,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Ltd Curated by ChEMBL					Assay Description Binding affinity against cloned human Dopamine receptor D4 using [3H]nemonapride as radioligand				J Med Chem 39: 1946-8 (1996) Article DOI: 10.1021/jm960017l BindingDB Entry DOI: 10.7270/Q2R49THW
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50470852 (CHEMBL57019) Show SMILES COc1cc2ccccc2cc1C(=O)OCC1CCN(Cc2ccccc2)C1 Show InChI InChI=1S/C24H25NO3/c1-27-23-14-21-10-6-5-9-20(21)13-22(23)24(26)28-17-19-11-12-25(16-19)15-18-7-3-2-4-8-18/h2-10,13-14,19H,11-12,15-17H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Ltd Curated by ChEMBL					Assay Description Binding affinity against cloned human Dopamine receptor D4 using [3H]nemonapride as radioligand				J Med Chem 39: 1946-8 (1996) Article DOI: 10.1021/jm960017l BindingDB Entry DOI: 10.7270/Q2R49THW
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50091438 ((E)-3-(3,4-Dichloro-phenyl)-N-{5-[4-(5-hydroxy-1H-...) Show SMILES Oc1ccc2[nH]cc(C3CCN(CCCCCNC(=O)\C=C\c4ccc(Cl)c(Cl)c4)CC3)c2c1 Show InChI InChI=1S/C27H31Cl2N3O2/c28-24-7-4-19(16-25(24)29)5-9-27(34)30-12-2-1-3-13-32-14-10-20(11-15-32)23-18-31-26-8-6-21(33)17-22(23)26/h4-9,16-18,20,31,33H,1-3,10-15H2,(H,30,34)/b9-5+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity for 5-hydroxytryptamine 2A receptor was determined				Bioorg Med Chem Lett 11: 2177-80 (2001) BindingDB Entry DOI: 10.7270/Q2BP023S
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50091438 ((E)-3-(3,4-Dichloro-phenyl)-N-{5-[4-(5-hydroxy-1H-...) Show SMILES Oc1ccc2[nH]cc(C3CCN(CCCCCNC(=O)\C=C\c4ccc(Cl)c(Cl)c4)CC3)c2c1 Show InChI InChI=1S/C27H31Cl2N3O2/c28-24-7-4-19(16-25(24)29)5-9-27(34)30-12-2-1-3-13-32-14-10-20(11-15-32)23-18-31-26-8-6-21(33)17-22(23)26/h4-9,16-18,20,31,33H,1-3,10-15H2,(H,30,34)/b9-5+	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	25	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity for 5-hydroxytryptamine 2B receptor was determined				Bioorg Med Chem Lett 11: 2177-80 (2001) BindingDB Entry DOI: 10.7270/Q2BP023S
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50470849 (CHEMBL59075) Show SMILES COc1cc2ccccc2cc1OCCC1CCN(Cc2ccccc2)CC1 Show InChI InChI=1S/C25H29NO2/c1-27-24-17-22-9-5-6-10-23(22)18-25(24)28-16-13-20-11-14-26(15-12-20)19-21-7-3-2-4-8-21/h2-10,17-18,20H,11-16,19H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	25	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Ltd Curated by ChEMBL					Assay Description Binding affinity against cloned human Dopamine receptor D4 using [3H]nemonapride as radioligand				J Med Chem 39: 1946-8 (1996) Article DOI: 10.1021/jm960017l BindingDB Entry DOI: 10.7270/Q2R49THW
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50470857 (CHEMBL299479) Show SMILES Clc1ccc(cc1)C(=O)OCC1CCN(Cc2ccccc2)CC1 Show InChI InChI=1S/C20H22ClNO2/c21-19-8-6-18(7-9-19)20(23)24-15-17-10-12-22(13-11-17)14-16-4-2-1-3-5-16/h1-9,17H,10-15H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	25	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Ltd Curated by ChEMBL					Assay Description Binding affinity against cloned human Dopamine receptor D4 using [3H]nemonapride as radioligand				J Med Chem 39: 1946-8 (1996) Article DOI: 10.1021/jm960017l BindingDB Entry DOI: 10.7270/Q2R49THW
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50222898 (CHEMBL9615) Show SMILES O=C1C(CCN2CCC(CC2)Oc2ccccc2)CCCc2ccccc12 Show InChI InChI=1S/C24H29NO2/c26-24-20(9-6-8-19-7-4-5-12-23(19)24)13-16-25-17-14-22(15-18-25)27-21-10-2-1-3-11-21/h1-5,7,10-12,20,22H,6,8-9,13-18H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	25	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Binding affinity at human cloned 5-hydroxytryptamine 7 receptor.				Bioorg Med Chem Lett 13: 1055-8 (2003) BindingDB Entry DOI: 10.7270/Q2X066D4
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50222891 (CHEMBL273821) Show SMILES O=C1N(CCN2CCC(CC2)n2c3ccccc3oc2=O)CCCc2ccccc12 Show InChI InChI=1S/C24H27N3O3/c28-23-20-8-2-1-6-18(20)7-5-13-26(23)17-16-25-14-11-19(12-15-25)27-21-9-3-4-10-22(21)30-24(27)29/h1-4,6,8-10,19H,5,7,11-17H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	28	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Binding affinity at human cloned 5-hydroxytryptamine 7 receptor.				Bioorg Med Chem Lett 13: 1055-8 (2003) BindingDB Entry DOI: 10.7270/Q2X066D4
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50222778 (CHEMBL275451) Show SMILES Fc1ccc(OC2CCN(CCN3CCCc4ccccc4C3=O)CC2)cc1 Show InChI InChI=1S/C23H27FN2O2/c24-19-7-9-20(10-8-19)28-21-11-14-25(15-12-21)16-17-26-13-3-5-18-4-1-2-6-22(18)23(26)27/h1-2,4,6-10,21H,3,5,11-17H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	32	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Binding affinity at human cloned 5-hydroxytryptamine 2A receptor.				Bioorg Med Chem Lett 13: 1055-8 (2003) BindingDB Entry DOI: 10.7270/Q2X066D4
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50470851 (CHEMBL57407) Show SMILES COc1cc2ccccc2cc1COCC1CCN(Cc2ccccc2)CC1 Show InChI InChI=1S/C25H29NO2/c1-27-25-16-23-10-6-5-9-22(23)15-24(25)19-28-18-21-11-13-26(14-12-21)17-20-7-3-2-4-8-20/h2-10,15-16,21H,11-14,17-19H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	32	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Ltd Curated by ChEMBL					Assay Description Binding affinity against cloned human Dopamine receptor D4 using [3H]nemonapride as radioligand				J Med Chem 39: 1946-8 (1996) Article DOI: 10.1021/jm960017l BindingDB Entry DOI: 10.7270/Q2R49THW
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50470856 (CHEMBL292186) Show SMILES COc1cc2ccccc2cc1C(=O)CCC1CCN(Cc2ccccc2)CC1 Show InChI InChI=1S/C26H29NO2/c1-29-26-18-23-10-6-5-9-22(23)17-24(26)25(28)12-11-20-13-15-27(16-14-20)19-21-7-3-2-4-8-21/h2-10,17-18,20H,11-16,19H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	32	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Ltd Curated by ChEMBL					Assay Description Binding affinity against cloned human Dopamine receptor D4 using [3H]nemonapride as radioligand				J Med Chem 39: 1946-8 (1996) Article DOI: 10.1021/jm960017l BindingDB Entry DOI: 10.7270/Q2R49THW
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50222892 (CHEMBL275258) Show SMILES O=C1Cc2ccccc2N1C1CCN(CCN2CCCc3ccccc3C2=O)CC1 Show InChI InChI=1S/C25H29N3O2/c29-24-18-20-7-2-4-10-23(20)28(24)21-11-14-26(15-12-21)16-17-27-13-5-8-19-6-1-3-9-22(19)25(27)30/h1-4,6-7,9-10,21H,5,8,11-18H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	37	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Binding affinity at human cloned 5-hydroxytryptamine 7 receptor.				Bioorg Med Chem Lett 13: 1055-8 (2003) BindingDB Entry DOI: 10.7270/Q2X066D4
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50470855 (CHEMBL60708) Show SMILES COc1cc2ccccc2cc1C(=O)NC1CCN(Cc2ccccc2)C1 Show InChI InChI=1S/C23H24N2O2/c1-27-22-14-19-10-6-5-9-18(19)13-21(22)23(26)24-20-11-12-25(16-20)15-17-7-3-2-4-8-17/h2-10,13-14,20H,11-12,15-16H2,1H3,(H,24,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Ltd Curated by ChEMBL					Assay Description Binding affinity against cloned human Dopamine receptor D2 (long) using [125I]iodosulpiride as radioligand				J Med Chem 39: 1946-8 (1996) Article DOI: 10.1021/jm960017l BindingDB Entry DOI: 10.7270/Q2R49THW
					More data for this Ligand-Target Pair
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50103142 ((E)-3-(3,4-Dichloro-phenyl)-N-{4-[(R)-3-((2S,7aS)-...) Show SMILES Oc1ccc2[nH]cc([C@H]3C[C@@H]4CC[C@H](C3)N4C[C@H]3CC[C@H](CC3)NC(=O)\C=C\c3ccc(Cl)c(Cl)c3)c2c1 |wU:10.16,8.7,20.25,17.18,13.15,THB:16:15:8.14.9:11.12,(1.43,-5.64,;2.76,-6.41,;2.76,-7.94,;4.09,-8.72,;5.49,-7.93,;6.98,-8.35,;7.82,-7.06,;6.89,-5.85,;7.28,-4.38,;6.21,-3.29,;6.63,-1.8,;7.03,-3.29,;8.1,-3.61,;9.19,-2.54,;8.77,-4.01,;8.12,-1.42,;7.05,-.12,;7.66,1.49,;6.75,2.73,;7.35,4.13,;8.89,4.31,;9.82,3.08,;9.19,1.66,;9.5,5.75,;10.97,6.18,;11.33,7.68,;12.09,5.13,;13.55,5.54,;14.67,4.49,;14.01,3.1,;14.88,1.83,;16.42,1.95,;17.28,.67,;17.1,3.35,;18.64,3.44,;16.24,4.61,;5.44,-6.39,;4.09,-5.62,)| Show InChI InChI=1S/C31H35Cl2N3O2/c32-28-10-3-19(13-29(28)33)4-12-31(38)35-22-5-1-20(2-6-22)18-36-23-7-8-24(36)15-21(14-23)27-17-34-30-11-9-25(37)16-26(27)30/h3-4,9-13,16-17,20-24,34,37H,1-2,5-8,14-15,18H2,(H,35,38)/b12-4+/t20-,21-,22+,23-,24+	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of [125I]-MCP-1 binding to the cloned C-C chemokine receptor type 2B expressed in CHO cells				Bioorg Med Chem Lett 11: 2177-80 (2001) BindingDB Entry DOI: 10.7270/Q2BP023S
					More data for this Ligand-Target Pair
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50103142 ((E)-3-(3,4-Dichloro-phenyl)-N-{4-[(R)-3-((2S,7aS)-...) Show SMILES Oc1ccc2[nH]cc([C@H]3C[C@@H]4CC[C@H](C3)N4C[C@H]3CC[C@H](CC3)NC(=O)\C=C\c3ccc(Cl)c(Cl)c3)c2c1 |wU:10.16,8.7,20.25,17.18,13.15,THB:16:15:8.14.9:11.12,(1.43,-5.64,;2.76,-6.41,;2.76,-7.94,;4.09,-8.72,;5.49,-7.93,;6.98,-8.35,;7.82,-7.06,;6.89,-5.85,;7.28,-4.38,;6.21,-3.29,;6.63,-1.8,;7.03,-3.29,;8.1,-3.61,;9.19,-2.54,;8.77,-4.01,;8.12,-1.42,;7.05,-.12,;7.66,1.49,;6.75,2.73,;7.35,4.13,;8.89,4.31,;9.82,3.08,;9.19,1.66,;9.5,5.75,;10.97,6.18,;11.33,7.68,;12.09,5.13,;13.55,5.54,;14.67,4.49,;14.01,3.1,;14.88,1.83,;16.42,1.95,;17.28,.67,;17.1,3.35,;18.64,3.44,;16.24,4.61,;5.44,-6.39,;4.09,-5.62,)| Show InChI InChI=1S/C31H35Cl2N3O2/c32-28-10-3-19(13-29(28)33)4-12-31(38)35-22-5-1-20(2-6-22)18-36-23-7-8-24(36)15-21(14-23)27-17-34-30-11-9-25(37)16-26(27)30/h3-4,9-13,16-17,20-24,34,37H,1-2,5-8,14-15,18H2,(H,35,38)/b12-4+/t20-,21-,22+,23-,24+	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity of the compound for C-C chemokine receptor type 2B was determined				Bioorg Med Chem Lett 11: 2177-80 (2001) BindingDB Entry DOI: 10.7270/Q2BP023S
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50222897 (CHEMBL9446) Show SMILES Fc1ccc2N(C3CCN(CCN4CCCc5ccccc5C4=O)CC3)C(=O)Cc2c1 Show InChI InChI=1S/C25H28FN3O2/c26-20-7-8-23-19(16-20)17-24(30)29(23)21-9-12-27(13-10-21)14-15-28-11-3-5-18-4-1-2-6-22(18)25(28)31/h1-2,4,6-8,16,21H,3,5,9-15,17H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	43	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Binding affinity at human cloned 5-hydroxytryptamine 2A receptor.				Bioorg Med Chem Lett 13: 1055-8 (2003) BindingDB Entry DOI: 10.7270/Q2X066D4
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50222899 (CHEMBL9347) Show SMILES Fc1ccc2n(nnc2c1)C1CCN(CCN2CCCc3ccccc3C2=O)CC1 Show InChI InChI=1S/C23H26FN5O/c24-18-7-8-22-21(16-18)25-26-29(22)19-9-12-27(13-10-19)14-15-28-11-3-5-17-4-1-2-6-20(17)23(28)30/h1-2,4,6-8,16,19H,3,5,9-15H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	49	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Binding affinity at human cloned 5-hydroxytryptamine 2A receptor.				Bioorg Med Chem Lett 13: 1055-8 (2003) BindingDB Entry DOI: 10.7270/Q2X066D4
					More data for this Ligand-Target Pair
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50091438 ((E)-3-(3,4-Dichloro-phenyl)-N-{5-[4-(5-hydroxy-1H-...) Show SMILES Oc1ccc2[nH]cc(C3CCN(CCCCCNC(=O)\C=C\c4ccc(Cl)c(Cl)c4)CC3)c2c1 Show InChI InChI=1S/C27H31Cl2N3O2/c28-24-7-4-19(16-25(24)29)5-9-27(34)30-12-2-1-3-13-32-14-10-20(11-15-32)23-18-31-26-8-6-21(33)17-22(23)26/h4-9,16-18,20,31,33H,1-3,10-15H2,(H,30,34)/b9-5+	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	50	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of [125I]MCP-1 binding to the cloned C-C chemokine receptor type 2B expressed in CHO cells				Bioorg Med Chem Lett 11: 2177-80 (2001) BindingDB Entry DOI: 10.7270/Q2BP023S
					More data for this Ligand-Target Pair
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50091438 ((E)-3-(3,4-Dichloro-phenyl)-N-{5-[4-(5-hydroxy-1H-...) Show SMILES Oc1ccc2[nH]cc(C3CCN(CCCCCNC(=O)\C=C\c4ccc(Cl)c(Cl)c4)CC3)c2c1 Show InChI InChI=1S/C27H31Cl2N3O2/c28-24-7-4-19(16-25(24)29)5-9-27(34)30-12-2-1-3-13-32-14-10-20(11-15-32)23-18-31-26-8-6-21(33)17-22(23)26/h4-9,16-18,20,31,33H,1-3,10-15H2,(H,30,34)/b9-5+	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	50	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					Assay Description Antagonist activity against C-C chemokine receptor type 2				Bioorg Med Chem Lett 10: 1803-6 (2000) BindingDB Entry DOI: 10.7270/Q2H70F2Z
					More data for this Ligand-Target Pair
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50091438 ((E)-3-(3,4-Dichloro-phenyl)-N-{5-[4-(5-hydroxy-1H-...) Show SMILES Oc1ccc2[nH]cc(C3CCN(CCCCCNC(=O)\C=C\c4ccc(Cl)c(Cl)c4)CC3)c2c1 Show InChI InChI=1S/C27H31Cl2N3O2/c28-24-7-4-19(16-25(24)29)5-9-27(34)30-12-2-1-3-13-32-14-10-20(11-15-32)23-18-31-26-8-6-21(33)17-22(23)26/h4-9,16-18,20,31,33H,1-3,10-15H2,(H,30,34)/b9-5+	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	50	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of [125I]-MCP-1 binding to the cloned C-C chemokine receptor type 2B expressed in CHO cells				Bioorg Med Chem Lett 11: 2177-80 (2001) BindingDB Entry DOI: 10.7270/Q2BP023S
					More data for this Ligand-Target Pair

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