Compile Data Set for Download or QSAR

Found 464 hits with Last Name = 'van wijngaarden' and Initial = 'i'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 3A/3B (Rattus norvegicus-RAT)	BDBM50042715 (1-(5,6-Dihydro-4H-pyrrolo[3,2,1-ij]quinolin-1-yl)-...) Show SMILES Cc1nc[nH]c1CCC(=O)c1cn2CCCc3cccc1c23 Show InChI InChI=1S/C18H19N3O/c1-12-16(20-11-19-12)7-8-17(22)15-10-21-9-3-5-13-4-2-6-14(15)18(13)21/h2,4,6,10-11H,3,5,7-9H2,1H3,(H,19,20)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	0.0750	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Solvay Duphar B.V. Curated by ChEMBL					Assay Description The binding affinity of the compound was measured on histamine H1 receptor using [3H]- mepyramine as radioligand.				J Med Chem 36: 3693-9 (1994) BindingDB Entry DOI: 10.7270/Q2NS0SZH
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50020178 (CHEMBL294633 | CHEMBL555633 | N-[2-(4-Benzofuran-7...) Show SMILES Fc1ccc(cc1)C(=O)NCCN1CCN(CC1)c1cccc2ccoc12 Show InChI InChI=1S/C21H22FN3O2/c22-18-6-4-17(5-7-18)21(26)23-9-10-24-11-13-25(14-12-24)19-3-1-2-16-8-15-27-20(16)19/h1-8,15H,9-14H2,(H,23,26)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.150	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Solvay Pharma Curated by ChEMBL					Assay Description Binding affinity was evaluated by determining in vitro displacement of [3H]-8-OH-DPAT from the central 5-hydroxytryptamine 1A receptor recognition si...				J Med Chem 40: 300-12 (1997) Article DOI: 10.1021/jm960496o BindingDB Entry DOI: 10.7270/Q27W6B96
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50020178 (CHEMBL294633 | CHEMBL555633 | N-[2-(4-Benzofuran-7...) Show SMILES Fc1ccc(cc1)C(=O)NCCN1CCN(CC1)c1cccc2ccoc12 Show InChI InChI=1S/C21H22FN3O2/c22-18-6-4-17(5-7-18)21(26)23-9-10-24-11-13-25(14-12-24)19-3-1-2-16-8-15-27-20(16)19/h1-8,15H,9-14H2,(H,23,26)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	0.150	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Solvay Duphar Research Laboratories Curated by ChEMBL					Assay Description Binding affinity to displace [3H]2-(di-N-propylamino)-8-hydroxy-tetralin from 5-hydroxytryptamine 1A (5-HT1A) receptor in rat frontal cortex homogena...				J Med Chem 37: 2761-73 (1994) BindingDB Entry DOI: 10.7270/Q2DJ5G84
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 3A/3B (Rattus norvegicus-RAT)	BDBM50231569 (Cilansetron | KC-9946) Show SMILES Cc1nccn1C[C@H]1CCc2c(C1=O)c1cccc3CCCn2c13 Show InChI InChI=1S/C20H21N3O/c1-13-21-9-11-22(13)12-15-7-8-17-18(20(15)24)16-6-2-4-14-5-3-10-23(17)19(14)16/h2,4,6,9,11,15H,3,5,7-8,10,12H2,1H3/t15-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	PubMed	0.190	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Solvay Duphar B.V. Curated by ChEMBL					Assay Description The binding affinity was measured on 5-hydroxytryptamine 3 receptor using [3H]GR-65630 as radioligand.				J Med Chem 36: 3693-9 (1994) BindingDB Entry DOI: 10.7270/Q2NS0SZH
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 3A/3B (Rattus norvegicus-RAT)	BDBM50042718 (1-(3,4-Dihydro-5-thia-2a-aza-acenaphthylen-1-yl)-3...) Show SMILES Cc1nc[nH]c1CCC(=O)c1cn2CCSc3cccc1c23 Show InChI InChI=1S/C17H17N3OS/c1-11-14(19-10-18-11)5-6-15(21)13-9-20-7-8-22-16-4-2-3-12(13)17(16)20/h2-4,9-10H,5-8H2,1H3,(H,18,19)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	0.190	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Solvay Duphar B.V. Curated by ChEMBL					Assay Description The binding affinity of the compound was measured on alpha2-adrenergic receptor using [3H]- clonidine as radioligand.				J Med Chem 36: 3693-9 (1994) BindingDB Entry DOI: 10.7270/Q2NS0SZH
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50039829 (CHEMBL92242 | Cyclohexanecarboxylic acid [2-(4-ben...) Show SMILES O=C(NCCN1CCN(CC1)c1cccc2ccoc12)C1CCCCC1 Show InChI InChI=1S/C21H29N3O2/c25-21(18-5-2-1-3-6-18)22-10-11-23-12-14-24(15-13-23)19-8-4-7-17-9-16-26-20(17)19/h4,7-9,16,18H,1-3,5-6,10-15H2,(H,22,25)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Solvay Duphar Research Laboratories Curated by ChEMBL					Assay Description Binding affinity to displace [3H]2-(di-N-propylamino)-8-hydroxy-tetralin from 5-hydroxytryptamine 1A (5-HT1A) receptor in rat frontal cortex homogena...				J Med Chem 37: 2761-73 (1994) BindingDB Entry DOI: 10.7270/Q2DJ5G84
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50403670 (CHEMBL311015) Show SMILES O=C1N(CCCCN2CCN(CC2)c2cccc3OCCOc23)C(=O)c2ccccc12 Show InChI InChI=1S/C24H27N3O4/c28-23-18-6-1-2-7-19(18)24(29)27(23)11-4-3-10-25-12-14-26(15-13-25)20-8-5-9-21-22(20)31-17-16-30-21/h1-2,5-9H,3-4,10-17H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.229	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Solvay Pharma Curated by ChEMBL					Assay Description Inhibition of [3H]8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor of rat frontal cortex membranes				Bioorg Med Chem Lett 8: 2457-62 (1999) BindingDB Entry DOI: 10.7270/Q2KS6SQ1
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 3A/3B (Rattus norvegicus-RAT)	BDBM50042714 (9-(2-Methyl-imidazol-1-ylmethyl)-4,5,8,9-tetrahydr...) Show SMILES Cc1nccn1CC1CCc2c(C1=O)c1cccc3CCn2c13 Show InChI InChI=1S/C19H19N3O/c1-12-20-8-10-21(12)11-14-5-6-16-17(19(14)23)15-4-2-3-13-7-9-22(16)18(13)15/h2-4,8,10,14H,5-7,9,11H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.230	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Solvay Duphar B.V. Curated by ChEMBL					Assay Description Displacement of [3H]GR-65630 binding to 5-hydroxytryptamine 3 receptor in rat brain cortical membranes				J Med Chem 36: 3693-9 (1994) BindingDB Entry DOI: 10.7270/Q2NS0SZH
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50039822 (1-(2-Cyclohexyl-ethyl)-4-(2,3-dihydro-benzo[1,4]di...) Show SMILES C(CN1CCN(CC1)c1cccc2OCCOc12)C1CCCCC1 Show InChI InChI=1S/C20H30N2O2/c1-2-5-17(6-3-1)9-10-21-11-13-22(14-12-21)18-7-4-8-19-20(18)24-16-15-23-19/h4,7-8,17H,1-3,5-6,9-16H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.25	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Solvay Duphar Research Laboratories Curated by ChEMBL					Assay Description Displacement of radioligand [3H]-2-(di-N-propylamino)-8-hydroxytetralin from 5-hydroxytryptamine 1A receptor in rat frontal cortex homogenate				J Med Chem 36: 2751-60 (1993) BindingDB Entry DOI: 10.7270/Q2CZ367F
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50039822 (1-(2-Cyclohexyl-ethyl)-4-(2,3-dihydro-benzo[1,4]di...) Show SMILES C(CN1CCN(CC1)c1cccc2OCCOc12)C1CCCCC1 Show InChI InChI=1S/C20H30N2O2/c1-2-5-17(6-3-1)9-10-21-11-13-22(14-12-21)18-7-4-8-19-20(18)24-16-15-23-19/h4,7-8,17H,1-3,5-6,9-16H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.25	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Solvay Duphar Research Laboratories Curated by ChEMBL					Assay Description Binding affinity to displace [3H]2-(di-N-propylamino)-8-hydroxy-tetralin from 5-hydroxytryptamine 1A (5-HT1A) receptor in rat frontal cortex homogena...				J Med Chem 37: 2761-73 (1994) BindingDB Entry DOI: 10.7270/Q2DJ5G84
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 3A/3B (Rattus norvegicus-RAT)	BDBM50042712 (10-(2-Methyl-imidazol-1-ylmethyl)-5,6,9,10-tetrahy...) Show SMILES Cc1nccn1CC1CCc2c(C1=O)c1cccc3CCCn2c13 Show InChI InChI=1S/C20H21N3O/c1-13-21-9-11-22(13)12-15-7-8-17-18(20(15)24)16-6-2-4-14-5-3-10-23(17)19(14)16/h2,4,6,9,11,15H,3,5,7-8,10,12H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	0.25	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Solvay Duphar B.V. Curated by ChEMBL					Assay Description Displacement of [3H]- GR-65,630 binding to 5-hydroxytryptamine 3 receptor in rat brain cortical membranes				J Med Chem 36: 3693-9 (1994) BindingDB Entry DOI: 10.7270/Q2NS0SZH
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 3A/3B (Rattus norvegicus-RAT)	BDBM50042713 (3-(5-Methyl-1H-imidazol-4-yl)-1-(1-methyl-1H-indol...) Show SMILES Cc1nc[nH]c1CCC(=O)c1cn(C)c2ccccc12 Show InChI InChI=1S/C16H17N3O/c1-11-14(18-10-17-11)7-8-16(20)13-9-19(2)15-6-4-3-5-12(13)15/h3-6,9-10H,7-8H2,1-2H3,(H,17,18)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	0.280	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Solvay Duphar B.V. Curated by ChEMBL					Assay Description The binding affinity of the compound was measured on glycine receptor using [3H]- strychnine as radioligand.				J Med Chem 36: 3693-9 (1994) BindingDB Entry DOI: 10.7270/Q2NS0SZH
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50403668 (CHEMBL312339) Show SMILES O=C1N(CCCCN2CCN(CC2)c2cccc3OCCOc23)S(=O)(=O)c2ccccc12 Show InChI InChI=1S/C23H27N3O5S/c27-23-18-6-1-2-9-21(18)32(28,29)26(23)11-4-3-10-24-12-14-25(15-13-24)19-7-5-8-20-22(19)31-17-16-30-20/h1-2,5-9H,3-4,10-17H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.288	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Solvay Pharma Curated by ChEMBL					Assay Description Inhibition of [3H]8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor of rat frontal cortex membranes				Bioorg Med Chem Lett 8: 2457-62 (1999) BindingDB Entry DOI: 10.7270/Q2KS6SQ1
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50039824 (CHEMBL81728 | N-{2-[4-(2,3-Dihydro-benzo[1,4]dioxi...) Show SMILES Fc1ccc(cc1)C(=O)NCCN1CCN(CC1)c1cccc2OCCOc12 Show InChI InChI=1S/C21H24FN3O3/c22-17-6-4-16(5-7-17)21(26)23-8-9-24-10-12-25(13-11-24)18-2-1-3-19-20(18)28-15-14-27-19/h1-7H,8-15H2,(H,23,26)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	0.295	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Solvay Pharma Curated by ChEMBL					Assay Description Inhibition of [3H]8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor of rat frontal cortex membranes				Bioorg Med Chem Lett 8: 2457-62 (1999) BindingDB Entry DOI: 10.7270/Q2KS6SQ1
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50039824 (CHEMBL81728 | N-{2-[4-(2,3-Dihydro-benzo[1,4]dioxi...) Show SMILES Fc1ccc(cc1)C(=O)NCCN1CCN(CC1)c1cccc2OCCOc12 Show InChI InChI=1S/C21H24FN3O3/c22-17-6-4-16(5-7-17)21(26)23-8-9-24-10-12-25(13-11-24)18-2-1-3-19-20(18)28-15-14-27-19/h1-7H,8-15H2,(H,23,26)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	0.300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Solvay Duphar Research Laboratories Curated by ChEMBL					Assay Description Binding affinity to displace [3H]2-(di-N-propylamino)-8-hydroxy-tetralin from 5-hydroxytryptamine 1A (5-HT1A) receptor in rat frontal cortex homogena...				J Med Chem 37: 2761-73 (1994) BindingDB Entry DOI: 10.7270/Q2DJ5G84
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50039824 (CHEMBL81728 | N-{2-[4-(2,3-Dihydro-benzo[1,4]dioxi...) Show SMILES Fc1ccc(cc1)C(=O)NCCN1CCN(CC1)c1cccc2OCCOc12 Show InChI InChI=1S/C21H24FN3O3/c22-17-6-4-16(5-7-17)21(26)23-8-9-24-10-12-25(13-11-24)18-2-1-3-19-20(18)28-15-14-27-19/h1-7H,8-15H2,(H,23,26)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Solvay Pharma Curated by ChEMBL					Assay Description Binding affinity was evaluated by determining in vitro displacement of [3H]-8-OH-DPAT from the central 5-hydroxytryptamine 1A receptor recognition si...				J Med Chem 40: 300-12 (1997) Article DOI: 10.1021/jm960496o BindingDB Entry DOI: 10.7270/Q27W6B96
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50056040 (CHEMBL107141 | Cyclohexanecarbothioic acid {2-[4-(...) Show SMILES COc1ccccc1N1CCN(CCNC(=S)C2CCCCC2)CC1 Show InChI InChI=1S/C20H31N3OS/c1-24-19-10-6-5-9-18(19)23-15-13-22(14-16-23)12-11-21-20(25)17-7-3-2-4-8-17/h5-6,9-10,17H,2-4,7-8,11-16H2,1H3,(H,21,25)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	0.320	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Solvay Pharma Curated by ChEMBL					Assay Description Binding affinity was evaluated by determining in vitro displacement of [3H]-8-OH-DPAT from the central 5-hydroxytryptamine 1A receptor recognition si...				J Med Chem 40: 300-12 (1997) Article DOI: 10.1021/jm960496o BindingDB Entry DOI: 10.7270/Q27W6B96
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50039818 (1-(2,3-Dihydro-benzo[1,4]dioxin-5-yl)-4-(4-phenyl-...) Show SMILES C(CCc1ccccc1)CN1CCN(CC1)c1cccc2OCCOc12 Show InChI InChI=1S/C22H28N2O2/c1-2-7-19(8-3-1)9-4-5-12-23-13-15-24(16-14-23)20-10-6-11-21-22(20)26-18-17-25-21/h1-3,6-8,10-11H,4-5,9,12-18H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.320	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Solvay Duphar Research Laboratories Curated by ChEMBL					Assay Description Binding affinity to displace [3H]2-(di-N-propylamino)-8-hydroxy-tetralin from 5-hydroxytryptamine 1A (5-HT1A) receptor in rat frontal cortex homogena...				J Med Chem 37: 2761-73 (1994) BindingDB Entry DOI: 10.7270/Q2DJ5G84
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50039818 (1-(2,3-Dihydro-benzo[1,4]dioxin-5-yl)-4-(4-phenyl-...) Show SMILES C(CCc1ccccc1)CN1CCN(CC1)c1cccc2OCCOc12 Show InChI InChI=1S/C22H28N2O2/c1-2-7-19(8-3-1)9-4-5-12-23-13-15-24(16-14-23)20-10-6-11-21-22(20)26-18-17-25-21/h1-3,6-8,10-11H,4-5,9,12-18H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.324	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Solvay Pharma Curated by ChEMBL					Assay Description Inhibition of [3H]8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor of rat frontal cortex membranes				Bioorg Med Chem Lett 8: 2457-62 (1999) BindingDB Entry DOI: 10.7270/Q2KS6SQ1
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 3A/3B (Rattus norvegicus-RAT)	BDBM50042720 (3-(5-Methyl-1H-imidazol-4-yl)-1-(4,5,6,7-tetrahydr...) Show SMILES Cc1nc[nH]c1CCC(=O)c1cn2CCCCc3cccc1c23 Show InChI InChI=1S/C19H21N3O/c1-13-17(21-12-20-13)8-9-18(23)16-11-22-10-3-2-5-14-6-4-7-15(16)19(14)22/h4,6-7,11-12H,2-3,5,8-10H2,1H3,(H,20,21)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.330	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Solvay Duphar B.V. Curated by ChEMBL					Assay Description The binding affinity of the compound was measured on muscarine M1 receptor using [3H]- pirenzepine as radioligand.				J Med Chem 36: 3693-9 (1994) BindingDB Entry DOI: 10.7270/Q2NS0SZH
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50039798 (1-Benzofuran-7-yl-4-phenethyl-piperazine; hydrochl...) Show SMILES C(Cc1ccccc1)N1CCN(CC1)c1cccc2ccoc12 Show InChI InChI=1S/C20H22N2O/c1-2-5-17(6-3-1)9-11-21-12-14-22(15-13-21)19-8-4-7-18-10-16-23-20(18)19/h1-8,10,16H,9,11-15H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.370	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Solvay Duphar Research Laboratories Curated by ChEMBL					Assay Description Binding affinity to displace [3H]2-(di-N-propylamino)-8-hydroxy-tetralin from 5-hydroxytryptamine 1A (5-HT1A) receptor in rat frontal cortex homogena...				J Med Chem 37: 2761-73 (1994) BindingDB Entry DOI: 10.7270/Q2DJ5G84
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50039821 (CHEMBL93421 | Cyclohexanecarboxylic acid {2-[4-(2,...) Show SMILES O=C(NCCN1CCN(CC1)c1cccc2OCCOc12)C1CCCCC1 Show InChI InChI=1S/C21H31N3O3/c25-21(17-5-2-1-3-6-17)22-9-10-23-11-13-24(14-12-23)18-7-4-8-19-20(18)27-16-15-26-19/h4,7-8,17H,1-3,5-6,9-16H2,(H,22,25)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.440	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Solvay Duphar Research Laboratories Curated by ChEMBL					Assay Description Binding affinity to displace [3H]2-(di-N-propylamino)-8-hydroxy-tetralin from 5-hydroxytryptamine 1A (5-HT1A) receptor in rat frontal cortex homogena...				J Med Chem 37: 2761-73 (1994) BindingDB Entry DOI: 10.7270/Q2DJ5G84
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50020174 (1-Benzofuran-7-yl-4-[5-(4-fluoro-phenyl)-1H-pyrrol...) Show SMILES Fc1ccc(cc1)-c1ccc(CN2CCN(CC2)c2cccc3ccoc23)[nH]1 Show InChI InChI=1S/C23H22FN3O/c24-19-6-4-17(5-7-19)21-9-8-20(25-21)16-26-11-13-27(14-12-26)22-3-1-2-18-10-15-28-23(18)22/h1-10,15,25H,11-14,16H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL MCE PC cid PC sid UniChem Patents	PubMed	0.450	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Duphar Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]-Spiperone from Dopamine receptor D2 in rat striatum				J Med Chem 31: 1934-40 (1988) BindingDB Entry DOI: 10.7270/Q2SJ1JMB
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50039810 (1-Benzofuran-7-yl-4-(2-phenoxy-ethyl)-piperazine; ...) Show SMILES C(CN1CCN(CC1)c1cccc2ccoc12)Oc1ccccc1 Show InChI InChI=1S/C20H22N2O2/c1-2-6-18(7-3-1)23-16-14-21-10-12-22(13-11-21)19-8-4-5-17-9-15-24-20(17)19/h1-9,15H,10-14,16H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	0.460	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Solvay Duphar Research Laboratories Curated by ChEMBL					Assay Description Binding affinity to displace [3H]2-(di-N-propylamino)-8-hydroxy-tetralin from 5-hydroxytryptamine 1A (5-HT1A) receptor in rat frontal cortex homogena...				J Med Chem 37: 2761-73 (1994) BindingDB Entry DOI: 10.7270/Q2DJ5G84
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50039800 (1-(2,3-Dihydro-benzo[1,4]dioxin-5-yl)-4-phenethyl-...) Show SMILES C(Cc1ccccc1)N1CCN(CC1)c1cccc2OCCOc12 Show InChI InChI=1S/C20H24N2O2/c1-2-5-17(6-3-1)9-10-21-11-13-22(14-12-21)18-7-4-8-19-20(18)24-16-15-23-19/h1-8H,9-16H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.470	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Solvay Duphar Research Laboratories Curated by ChEMBL					Assay Description Binding affinity to displace [3H]2-(di-N-propylamino)-8-hydroxy-tetralin from 5-hydroxytryptamine 1A (5-HT1A) receptor in rat frontal cortex homogena...				J Med Chem 37: 2761-73 (1994) BindingDB Entry DOI: 10.7270/Q2DJ5G84
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50039819 (1-(2,3-Dihydro-benzo[1,4]dioxin-5-yl)-4-hexyl-pipe...) Show SMILES CCCCCCN1CCN(CC1)c1cccc2OCCOc12 Show InChI InChI=1S/C18H28N2O2/c1-2-3-4-5-9-19-10-12-20(13-11-19)16-7-6-8-17-18(16)22-15-14-21-17/h6-8H,2-5,9-15H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Solvay Duphar Research Laboratories Curated by ChEMBL					Assay Description Displacement of radioligand [3H]-2-(di-N-propylamino)-8-hydroxytetralin from 5-hydroxytryptamine 1A receptor in rat frontal cortex homogenate				J Med Chem 36: 2751-60 (1993) BindingDB Entry DOI: 10.7270/Q2CZ367F
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50039819 (1-(2,3-Dihydro-benzo[1,4]dioxin-5-yl)-4-hexyl-pipe...) Show SMILES CCCCCCN1CCN(CC1)c1cccc2OCCOc12 Show InChI InChI=1S/C18H28N2O2/c1-2-3-4-5-9-19-10-12-20(13-11-19)16-7-6-8-17-18(16)22-15-14-21-17/h6-8H,2-5,9-15H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Solvay Duphar Research Laboratories Curated by ChEMBL					Assay Description Binding affinity to displace [3H]2-(di-N-propylamino)-8-hydroxy-tetralin from 5-hydroxytryptamine 1A (5-HT1A) receptor in rat frontal cortex homogena...				J Med Chem 37: 2761-73 (1994) BindingDB Entry DOI: 10.7270/Q2DJ5G84
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM86708 (CAS_146714-97-8 | CHEMBL31354 | CHEMBL514874 | CHE...) Show SMILES COc1ccccc1N1CCN(CCN(C(=O)C2CCCCC2)c2ccccn2)CC1 Show InChI InChI=1S/C25H34N4O2/c1-31-23-12-6-5-11-22(23)28-18-15-27(16-19-28)17-20-29(24-13-7-8-14-26-24)25(30)21-9-3-2-4-10-21/h5-8,11-14,21H,2-4,9-10,15-20H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	0.501	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Solvay Pharma Curated by ChEMBL					Assay Description Compound was tested for inhibition constant against 5-hydroxytryptamine 1A receptor in rat frontal cortex membranes.				Bioorg Med Chem Lett 8: 2457-62 (1999) BindingDB Entry DOI: 10.7270/Q2KS6SQ1
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50039805 (1-Benzofuran-7-yl-4-hexyl-piperazine | CHEMBL27558) Show SMILES CCCCCCN1CCN(CC1)c1cccc2ccoc12 Show InChI InChI=1S/C18H26N2O/c1-2-3-4-5-10-19-11-13-20(14-12-19)17-8-6-7-16-9-15-21-18(16)17/h6-9,15H,2-5,10-14H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.540	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Solvay Duphar Research Laboratories Curated by ChEMBL					Assay Description Binding affinity to displace [3H]2-(di-N-propylamino)-8-hydroxy-tetralin from 5-hydroxytryptamine 1A (5-HT1A) receptor in rat frontal cortex homogena...				J Med Chem 37: 2761-73 (1994) BindingDB Entry DOI: 10.7270/Q2DJ5G84
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50039805 (1-Benzofuran-7-yl-4-hexyl-piperazine | CHEMBL27558) Show SMILES CCCCCCN1CCN(CC1)c1cccc2ccoc12 Show InChI InChI=1S/C18H26N2O/c1-2-3-4-5-10-19-11-13-20(14-12-19)17-8-6-7-16-9-15-21-18(16)17/h6-9,15H,2-5,10-14H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.540	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Solvay Duphar Research Laboratories Curated by ChEMBL					Assay Description Displacement of radioligand [3H]-2-(di-N-propylamino)-8-hydroxytetralin from 5-hydroxytryptamine 1A receptor in rat frontal cortex homogenate				J Med Chem 36: 2751-60 (1993) BindingDB Entry DOI: 10.7270/Q2CZ367F
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50039796 (1-(2,3-Dihydro-benzo[1,4]dioxin-5-yl)-4-octyl-pipe...) Show SMILES CCCCCCCCN1CCN(CC1)c1cccc2OCCOc12 Show InChI InChI=1S/C20H32N2O2/c1-2-3-4-5-6-7-11-21-12-14-22(15-13-21)18-9-8-10-19-20(18)24-17-16-23-19/h8-10H,2-7,11-17H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.610	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Solvay Duphar Research Laboratories Curated by ChEMBL					Assay Description Binding affinity to displace [3H]2-(di-N-propylamino)-8-hydroxy-tetralin from 5-hydroxytryptamine 1A (5-HT1A) receptor in rat frontal cortex homogena...				J Med Chem 37: 2761-73 (1994) BindingDB Entry DOI: 10.7270/Q2DJ5G84
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50039796 (1-(2,3-Dihydro-benzo[1,4]dioxin-5-yl)-4-octyl-pipe...) Show SMILES CCCCCCCCN1CCN(CC1)c1cccc2OCCOc12 Show InChI InChI=1S/C20H32N2O2/c1-2-3-4-5-6-7-11-21-12-14-22(15-13-21)18-9-8-10-19-20(18)24-17-16-23-19/h8-10H,2-7,11-17H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.610	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Solvay Duphar Research Laboratories Curated by ChEMBL					Assay Description Displacement of radioligand [3H]-2-(di-N-propylamino)-8-hydroxytetralin from 5-hydroxytryptamine 1A receptor in rat frontal cortex homogenate				J Med Chem 36: 2751-60 (1993) BindingDB Entry DOI: 10.7270/Q2CZ367F
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 3A/3B (Rattus norvegicus-RAT)	BDBM50042711 (11-(2-Methyl-imidazol-1-ylmethyl)-4,5,6,7,10,11-he...) Show SMILES Cc1nccn1CC1CCc2c(C1=O)c1cccc3CCCCn2c13 Show InChI InChI=1S/C21H23N3O/c1-14-22-10-12-23(14)13-16-8-9-18-19(21(16)25)17-7-4-6-15-5-2-3-11-24(18)20(15)17/h4,6-7,10,12,16H,2-3,5,8-9,11,13H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.640	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Solvay Duphar B.V. Curated by ChEMBL					Assay Description The binding affinity of the compound was measured on dopamine receptor D1 using [3H]- dopamine as radioligand.				J Med Chem 36: 3693-9 (1994) BindingDB Entry DOI: 10.7270/Q2NS0SZH
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 3A/3B (Rattus norvegicus-RAT)	BDBM50042711 (11-(2-Methyl-imidazol-1-ylmethyl)-4,5,6,7,10,11-he...) Show SMILES Cc1nccn1CC1CCc2c(C1=O)c1cccc3CCCCn2c13 Show InChI InChI=1S/C21H23N3O/c1-14-22-10-12-23(14)13-16-8-9-18-19(21(16)25)17-7-4-6-15-5-2-3-11-24(18)20(15)17/h4,6-7,10,12,16H,2-3,5,8-9,11,13H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.640	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Solvay Duphar B.V. Curated by ChEMBL					Assay Description The binding affinity of the compound was measured on 5-hydroxytryptamine 1C receptor using [3H]- serotonin as radioligand.				J Med Chem 36: 3693-9 (1994) BindingDB Entry DOI: 10.7270/Q2NS0SZH
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50039814 (4-[4-(2,3-Dihydro-benzo[1,4]dioxin-5-yl)-piperazin...) Show SMILES O=C(CCCN1CCN(CC1)c1cccc2OCCOc12)c1ccccc1 Show InChI InChI=1S/C22H26N2O3/c25-20(18-6-2-1-3-7-18)9-5-11-23-12-14-24(15-13-23)19-8-4-10-21-22(19)27-17-16-26-21/h1-4,6-8,10H,5,9,11-17H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.670	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Solvay Duphar Research Laboratories Curated by ChEMBL					Assay Description Binding affinity to displace [3H]2-(di-N-propylamino)-8-hydroxy-tetralin from 5-hydroxytryptamine 1A (5-HT1A) receptor in rat frontal cortex homogena...				J Med Chem 37: 2761-73 (1994) BindingDB Entry DOI: 10.7270/Q2DJ5G84
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50039814 (4-[4-(2,3-Dihydro-benzo[1,4]dioxin-5-yl)-piperazin...) Show SMILES O=C(CCCN1CCN(CC1)c1cccc2OCCOc12)c1ccccc1 Show InChI InChI=1S/C22H26N2O3/c25-20(18-6-2-1-3-7-18)9-5-11-23-12-14-24(15-13-23)19-8-4-10-21-22(19)27-17-16-26-21/h1-4,6-8,10H,5,9,11-17H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.676	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Solvay Pharma Curated by ChEMBL					Assay Description Inhibition of [3H]8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor of rat frontal cortex membranes				Bioorg Med Chem Lett 8: 2457-62 (1999) BindingDB Entry DOI: 10.7270/Q2KS6SQ1
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50020177 (1-(3,4-Dihydro-2H-benzo[b][1,4]dioxepin-6-yl)-4-(5...) Show SMILES C(N1CCN(CC1)c1cccc2OCCCOc12)c1ccc([nH]1)-c1ccccc1 Show InChI InChI=1S/C24H27N3O2/c1-2-6-19(7-3-1)21-11-10-20(25-21)18-26-12-14-27(15-13-26)22-8-4-9-23-24(22)29-17-5-16-28-23/h1-4,6-11,25H,5,12-18H2	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	0.680	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Duphar Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]-Spiperone from Dopamine receptor D2 in rat striatum				J Med Chem 31: 1934-40 (1988) BindingDB Entry DOI: 10.7270/Q2SJ1JMB
					More data for this Ligand-Target Pair
Cholecystokinin receptor type A (RAT)	BDBM50005463 ((R)-1H-Indole-2-carboxylic acid (1-methyl-2-oxo-5-...) Show SMILES CN1c2ccccc2C(=N[C@H](NC(=O)c2cc3ccccc3[nH]2)C1=O)c1ccccc1 |r,c:9| Show InChI InChI=1S/C25H20N4O2/c1-29-21-14-8-6-12-18(21)22(16-9-3-2-4-10-16)27-23(25(29)31)28-24(30)20-15-17-11-5-7-13-19(17)26-20/h2-15,23,26H,1H3,(H,28,30)/t23-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PubMed	0.700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Center for Bio-Pharmaceutical Sciences Curated by ChEMBL					Assay Description Inhibition of [3H]-L-364,718 binding to cholecystokinin type A receptor in rat pancreas membranes				J Med Chem 35: 1042-9 (1992) BindingDB Entry DOI: 10.7270/Q2HT2N8R
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM85079 (2-[4-[4-[(7-Chloro-2,3-dihydro-1,4-benzodioxin)-5-...) Show SMILES Clc1cc2OCCOc2c(c1)N1CCN(CCCCN2C(=O)c3ccccc3S2(=O)=O)CC1 Show InChI InChI=1S/C23H26ClN3O5S/c24-17-15-19(22-20(16-17)31-13-14-32-22)26-11-9-25(10-12-26)7-3-4-8-27-23(28)18-5-1-2-6-21(18)33(27,29)30/h1-2,5-6,15-16H,3-4,7-14H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	0.708	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Solvay Pharma Curated by ChEMBL					Assay Description Inhibition of [3H]8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor of rat frontal cortex membranes				Bioorg Med Chem Lett 8: 2457-62 (1999) BindingDB Entry DOI: 10.7270/Q2KS6SQ1
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50470650 (CHEMBL335401) Show SMILES O=C1CC2(CCCC2)CC(=O)N1CCN1CCN(CC1)c1cccc2OCCOc12 Show InChI InChI=1S/C23H31N3O4/c27-20-16-23(6-1-2-7-23)17-21(28)26(20)13-10-24-8-11-25(12-9-24)18-4-3-5-19-22(18)30-15-14-29-19/h3-5H,1-2,6-17H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	0.708	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Solvay Duphar Research Laboratories Curated by ChEMBL					Assay Description Inhibition of [3H]2-(di-N-propylamino)-8-hydroxytetralin binding to 5-HT1A receptor of rat frontal cortex homogenates				J Med Chem 38: 4303-8 (1995) Article DOI: 10.1021/jm00021a020 BindingDB Entry DOI: 10.7270/Q25B056C
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50039807 (1-(2,3-Dihydro-benzo[1,4]dioxin-5-yl)-4-(2-phenoxy...) Show SMILES C(CN1CCN(CC1)c1cccc2OCCOc12)Oc1ccccc1 Show InChI InChI=1S/C20H24N2O3/c1-2-5-17(6-3-1)23-14-13-21-9-11-22(12-10-21)18-7-4-8-19-20(18)25-16-15-24-19/h1-8H,9-16H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.730	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Solvay Duphar Research Laboratories Curated by ChEMBL					Assay Description Binding affinity to displace [3H]2-(di-N-propylamino)-8-hydroxy-tetralin from 5-hydroxytryptamine 1A (5-HT1A) receptor in rat frontal cortex homogena...				J Med Chem 37: 2761-73 (1994) BindingDB Entry DOI: 10.7270/Q2DJ5G84
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 3A/3B (Rattus norvegicus-RAT)	BDBM50042711 (11-(2-Methyl-imidazol-1-ylmethyl)-4,5,6,7,10,11-he...) Show SMILES Cc1nccn1CC1CCc2c(C1=O)c1cccc3CCCCn2c13 Show InChI InChI=1S/C21H23N3O/c1-14-22-10-12-23(14)13-16-8-9-18-19(21(16)25)17-7-4-6-15-5-2-3-11-24(18)20(15)17/h4,6-7,10,12,16H,2-3,5,8-9,11,13H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.75	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Solvay Duphar B.V. Curated by ChEMBL					Assay Description Displacement of [3H]- GR-65,630 binding to 5-hydroxytryptamine 3 receptor in rat brain cortical membranes				J Med Chem 36: 3693-9 (1994) BindingDB Entry DOI: 10.7270/Q2NS0SZH
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50020182 (1-(2-Methoxy-phenyl)-4-(5-phenyl-1H-pyrrol-2-ylmet...) Show SMILES COc1ccccc1N1CCN(Cc2ccc([nH]2)-c2ccccc2)CC1 Show InChI InChI=1S/C22H25N3O/c1-26-22-10-6-5-9-21(22)25-15-13-24(14-16-25)17-19-11-12-20(23-19)18-7-3-2-4-8-18/h2-12,23H,13-17H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	0.760	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Duphar Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]-Spiperone from Dopamine receptor D2 in rat striatum				J Med Chem 31: 1934-40 (1988) BindingDB Entry DOI: 10.7270/Q2SJ1JMB
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 3A/3B (Rattus norvegicus-RAT)	BDBM50042719 (8-(2-Methyl-imidazol-1-ylmethyl)-1,2,9,10-tetrahyd...) Show SMILES Cc1nccn1CC1CCc2c(C1=O)c1cccc3SCCn2c13 Show InChI InChI=1S/C19H19N3OS/c1-12-20-7-8-21(12)11-13-5-6-15-17(19(13)23)14-3-2-4-16-18(14)22(15)9-10-24-16/h2-4,7-8,13H,5-6,9-11H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.770	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Solvay Duphar B.V. Curated by ChEMBL					Assay Description Displacement of [3H]- GR-65,630 binding to 5-hydroxytryptamine 3 receptor in rat brain cortical membranes				J Med Chem 36: 3693-9 (1994) BindingDB Entry DOI: 10.7270/Q2NS0SZH
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 3A/3B (Rattus norvegicus-RAT)	BDBM50000483 ((BRL 43694)1-Methyl-1H-indazole-3-carboxylic acid ...) Show SMILES CN1C2CCCC1CC(C2)NC(=O)c1nn(C)c2ccccc12 |THB:10:8:1:3.5.4| Show InChI InChI=1S/C18H24N4O/c1-21-13-6-5-7-14(21)11-12(10-13)19-18(23)17-15-8-3-4-9-16(15)22(2)20-17/h3-4,8-9,12-14H,5-7,10-11H2,1-2H3,(H,19,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid PDB UniChem Patents Similars	PDB PubMed	0.780	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Solvay Duphar B.V. Curated by ChEMBL					Assay Description Displacement of [3H]- GR-65,630 binding to 5-hydroxytryptamine 3 receptor in rat brain cortical membranes				J Med Chem 36: 3693-9 (1994) BindingDB Entry DOI: 10.7270/Q2NS0SZH
					More data for this Ligand-Target Pair				3D Structure (crystal)
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50056034 (CHEMBL108229 | Cyclohexanecarboxylic acid {2-[4-(2...) Show SMILES COc1ccccc1N1CCN(CCNC(=O)C2CCCCC2)CC1 Show InChI InChI=1S/C20H31N3O2/c1-25-19-10-6-5-9-18(19)23-15-13-22(14-16-23)12-11-21-20(24)17-7-3-2-4-8-17/h5-6,9-10,17H,2-4,7-8,11-16H2,1H3,(H,21,24)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Solvay Pharma Curated by ChEMBL					Assay Description Binding affinity was evaluated by determining in vitro displacement of [3H]-8-OH-DPAT from the central 5-hydroxytryptamine 1A receptor recognition si...				J Med Chem 40: 300-12 (1997) Article DOI: 10.1021/jm960496o BindingDB Entry DOI: 10.7270/Q27W6B96
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50039795 (1-Benzofuran-7-yl-4-pentyl-piperazine | CHEMBL2683...) Show SMILES CCCCCN1CCN(CC1)c1cccc2ccoc12 Show InChI InChI=1S/C17H24N2O/c1-2-3-4-9-18-10-12-19(13-11-18)16-7-5-6-15-8-14-20-17(15)16/h5-8,14H,2-4,9-13H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	0.810	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Solvay Duphar Research Laboratories Curated by ChEMBL					Assay Description Displacement of radioligand [3H]-2-(di-N-propylamino)-8-hydroxytetralin from 5-hydroxytryptamine 1A receptor in rat frontal cortex homogenate				J Med Chem 36: 2751-60 (1993) BindingDB Entry DOI: 10.7270/Q2CZ367F
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50039795 (1-Benzofuran-7-yl-4-pentyl-piperazine | CHEMBL2683...) Show SMILES CCCCCN1CCN(CC1)c1cccc2ccoc12 Show InChI InChI=1S/C17H24N2O/c1-2-3-4-9-18-10-12-19(13-11-18)16-7-5-6-15-8-14-20-17(15)16/h5-8,14H,2-4,9-13H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	0.810	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Solvay Duphar Research Laboratories Curated by ChEMBL					Assay Description Binding affinity to displace [3H]2-(di-N-propylamino)-8-hydroxy-tetralin from 5-hydroxytryptamine 1A (5-HT1A) receptor in rat frontal cortex homogena...				J Med Chem 37: 2761-73 (1994) BindingDB Entry DOI: 10.7270/Q2DJ5G84
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50039802 (1-Benzofuran-7-yl-4-(3-phenoxy-propyl)-piperazine;...) Show SMILES C(COc1ccccc1)CN1CCN(CC1)c1cccc2ccoc12 Show InChI InChI=1S/C21H24N2O2/c1-2-7-19(8-3-1)24-16-5-11-22-12-14-23(15-13-22)20-9-4-6-18-10-17-25-21(18)20/h1-4,6-10,17H,5,11-16H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	0.850	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Solvay Duphar Research Laboratories Curated by ChEMBL					Assay Description Binding affinity to displace [3H]2-(di-N-propylamino)-8-hydroxy-tetralin from 5-hydroxytryptamine 1A (5-HT1A) receptor in rat frontal cortex homogena...				J Med Chem 37: 2761-73 (1994) BindingDB Entry DOI: 10.7270/Q2DJ5G84
					More data for this Ligand-Target Pair
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM50019959 (1-(4-Fluoro-phenyl)-4-[4-(2-methoxy-phenyl)-pipera...) Show SMILES COc1ccccc1N1CCN(CCCC(=O)c2ccc(F)cc2)CC1 Show InChI InChI=1S/C21H25FN2O2/c1-26-21-7-3-2-5-19(21)24-15-13-23(14-16-24)12-4-6-20(25)17-8-10-18(22)11-9-17/h2-3,5,7-11H,4,6,12-16H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	0.870	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Duphar Research Laboratories Curated by ChEMBL					Assay Description Potency to displace [3H]- WB-4101 from alpha-1 adrenergic receptor in rat striatum				J Med Chem 31: 1934-40 (1988) BindingDB Entry DOI: 10.7270/Q2SJ1JMB
					More data for this Ligand-Target Pair

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