Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
C-X-C chemokine receptor type 4 (Homo sapiens (Human)) | BDBM50270276 (CHEMBL477121 | N-[1,4,8,11-Tetraazacyclotetradecan...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents | Article PubMed | 10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Antagonist activity at human wild type CXCR4 expressed in COS7 cells coexpressing G protein Gqi4myr assessed as inhibition of CXCL12-induced phosphat... | J Biol Chem 282: 27354-65 (2007) Article DOI: 10.1074/jbc.M704739200 BindingDB Entry DOI: 10.7270/Q26Q1X1Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-X-C chemokine receptor type 4 (Homo sapiens (Human)) | BDBM50270276 (CHEMBL477121 | N-[1,4,8,11-Tetraazacyclotetradecan...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents | Article PubMed | 110 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Displacement of [125I]12G5 antibody from human wild type CXCR4 expressed in COS7 cells | J Biol Chem 282: 27354-65 (2007) Article DOI: 10.1074/jbc.M704739200 BindingDB Entry DOI: 10.7270/Q26Q1X1Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-X-C chemokine receptor type 4 (Homo sapiens (Human)) | BDBM50035696 (1,1''-{1,4-phenylenebis(methylene)}-bis{1,4,8,11-t...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 220 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Antagonist activity at human wild type CXCR4 expressed in COS7 cells coexpressing G protein Gqi4myr assessed as inhibition of CXCL12-induced phosphat... | J Biol Chem 282: 27354-65 (2007) Article DOI: 10.1074/jbc.M704739200 BindingDB Entry DOI: 10.7270/Q26Q1X1Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-X-C chemokine receptor type 4 (Homo sapiens (Human)) | BDBM50035696 (1,1''-{1,4-phenylenebis(methylene)}-bis{1,4,8,11-t...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 890 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Displacement of [125I]12G5 antibody from human wild type CXCR4 expressed in COS7 cells | J Biol Chem 282: 27354-65 (2007) Article DOI: 10.1074/jbc.M704739200 BindingDB Entry DOI: 10.7270/Q26Q1X1Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-X-C chemokine receptor type 4 (Homo sapiens (Human)) | BDBM50270277 (Benzyl-[4-(1,4,8,11tetraaza-cyclotetradec-1-ylmeth...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Antagonist activity at human wild type CXCR4 expressed in COS7 cells coexpressing G protein Gqi4myr assessed as inhibition of CXCL12-induced phosphat... | J Biol Chem 282: 27354-65 (2007) Article DOI: 10.1074/jbc.M704739200 BindingDB Entry DOI: 10.7270/Q26Q1X1Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
C-X-C chemokine receptor type 4 (Homo sapiens (Human)) | BDBM50035719 (1-(4-Methyl-benzyl)-1,4,8,11tetraaza-cyclotetradec...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Copenhagen Curated by ChEMBL | Assay Description Antagonist activity at human wild type CXCR4 expressed in COS7 cells coexpressing G protein Gqi4myr assessed as inhibition of CXCL12-induced phosphat... | J Biol Chem 282: 27354-65 (2007) Article DOI: 10.1074/jbc.M704739200 BindingDB Entry DOI: 10.7270/Q26Q1X1Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin D2 receptor 2 (Homo sapiens (Human)) | BDBM50200260 (4-bromo-2-[1-(4-bromophenyl)-1H-pyrazole-4-carbony...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.40 | n/a | n/a | n/a | n/a | n/a | n/a |
7TM Pharma Curated by ChEMBL | Assay Description Displacement of [3H]PGD2 from human CRTH2 receptor expressed in HEK293 cells | J Med Chem 49: 6638-41 (2006) Article DOI: 10.1021/jm060657g BindingDB Entry DOI: 10.7270/Q2DF6QV0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin D2 receptor 2 (Homo sapiens (Human)) | BDBM50200271 (4-bromo-2-(1-phenyl-1H-pyrazole-4-carbonyl)phenoxy...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.5 | n/a | n/a | n/a | n/a | n/a | n/a |
7TM Pharma Curated by ChEMBL | Assay Description Displacement of [3H]PGD2 from human CRTH2 receptor expressed in HEK293 cells | J Med Chem 49: 6638-41 (2006) Article DOI: 10.1021/jm060657g BindingDB Entry DOI: 10.7270/Q2DF6QV0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin D2 receptor 2 (Homo sapiens (Human)) | BDBM50200266 (4-bromo-2-[1-(4-chlorophenyl)-1H-pyrazole-4-carbon...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.5 | n/a | n/a | n/a | n/a | n/a | n/a |
7TM Pharma Curated by ChEMBL | Assay Description Displacement of [3H]PGD2 from human CRTH2 receptor expressed in HEK293 cells | J Med Chem 49: 6638-41 (2006) Article DOI: 10.1021/jm060657g BindingDB Entry DOI: 10.7270/Q2DF6QV0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin D2 receptor 2 (Homo sapiens (Human)) | BDBM50200265 (4-bromo-2-[1-(2-bromophenyl)-1H-pyrazole-4-carbony...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.90 | n/a | n/a | n/a | n/a | n/a | n/a |
7TM Pharma Curated by ChEMBL | Assay Description Displacement of [3H]PGD2 from human CRTH2 receptor expressed in HEK293 cells | J Med Chem 49: 6638-41 (2006) Article DOI: 10.1021/jm060657g BindingDB Entry DOI: 10.7270/Q2DF6QV0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin D2 receptor 2 (Mus musculus (mouse)) | BDBM50200271 (4-bromo-2-(1-phenyl-1H-pyrazole-4-carbonyl)phenoxy...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 3.20 | n/a | n/a | n/a | n/a | n/a | n/a |
7TM Pharma Curated by ChEMBL | Assay Description Inhibition of mouse CRTH2 receptor | J Med Chem 49: 6638-41 (2006) Article DOI: 10.1021/jm060657g BindingDB Entry DOI: 10.7270/Q2DF6QV0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin D2 receptor 2 (Homo sapiens (Human)) | BDBM50200262 (4-bromo-2-[1-(3-bromophenyl)-1H-pyrazole-4-carbony...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 3.40 | n/a | n/a | n/a | n/a | n/a | n/a |
7TM Pharma Curated by ChEMBL | Assay Description Displacement of [3H]PGD2 from human CRTH2 receptor expressed in HEK293 cells | J Med Chem 49: 6638-41 (2006) Article DOI: 10.1021/jm060657g BindingDB Entry DOI: 10.7270/Q2DF6QV0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin D2 receptor 2 (Homo sapiens (Human)) | BDBM50200247 (4-bromo-2-[1-(4-methoxyphenyl)-1H-pyrazole-4-carbo...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 3.60 | n/a | n/a | n/a | n/a | n/a | n/a |
7TM Pharma Curated by ChEMBL | Assay Description Displacement of [3H]PGD2 from human CRTH2 receptor expressed in HEK293 cells | J Med Chem 49: 6638-41 (2006) Article DOI: 10.1021/jm060657g BindingDB Entry DOI: 10.7270/Q2DF6QV0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin D2 receptor 2 (Homo sapiens (Human)) | BDBM50200265 (4-bromo-2-[1-(2-bromophenyl)-1H-pyrazole-4-carbony...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
7TM Pharma Curated by ChEMBL | Assay Description Antagonist activity against CRTH2 receptor measured as inhibition of PGD2-induced beta-arrestin translocation in HEK293 cells by BRET assay | J Med Chem 49: 6638-41 (2006) Article DOI: 10.1021/jm060657g BindingDB Entry DOI: 10.7270/Q2DF6QV0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin D2 receptor 2 (Homo sapiens (Human)) | BDBM50200260 (4-bromo-2-[1-(4-bromophenyl)-1H-pyrazole-4-carbony...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
7TM Pharma Curated by ChEMBL | Assay Description Antagonist activity against CRTH2 receptor measured as inhibition of PGD2-induced beta-arrestin translocation in HEK293 cells by BRET assay | J Med Chem 49: 6638-41 (2006) Article DOI: 10.1021/jm060657g BindingDB Entry DOI: 10.7270/Q2DF6QV0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin D2 receptor 2 (Homo sapiens (Human)) | BDBM50200267 (CHEMBL214668 | [3',5'-difluoro-3-(1-phenyl-1H-pyra...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
7TM Pharma Curated by ChEMBL | Assay Description Displacement of [3H]PGD2 from human CRTH2 receptor expressed in HEK293 cells | J Med Chem 49: 6638-41 (2006) Article DOI: 10.1021/jm060657g BindingDB Entry DOI: 10.7270/Q2DF6QV0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin D2 receptor 2 (Homo sapiens (Human)) | BDBM50200270 (4-chloro-2-(1-phenyl-1H-pyrazole-4-carbonyl)phenox...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 15 | n/a | n/a | n/a | n/a | n/a | n/a |
7TM Pharma Curated by ChEMBL | Assay Description Displacement of [3H]PGD2 from human CRTH2 receptor expressed in HEK293 cells | J Med Chem 49: 6638-41 (2006) Article DOI: 10.1021/jm060657g BindingDB Entry DOI: 10.7270/Q2DF6QV0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin D2 receptor 2 (Homo sapiens (Human)) | BDBM50200266 (4-bromo-2-[1-(4-chlorophenyl)-1H-pyrazole-4-carbon...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a | n/a |
7TM Pharma Curated by ChEMBL | Assay Description Antagonist activity against CRTH2 receptor measured as inhibition of PGD2-induced beta-arrestin translocation in HEK293 cells by BRET assay | J Med Chem 49: 6638-41 (2006) Article DOI: 10.1021/jm060657g BindingDB Entry DOI: 10.7270/Q2DF6QV0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin D2 receptor 2 (Homo sapiens (Human)) | BDBM50200271 (4-bromo-2-(1-phenyl-1H-pyrazole-4-carbonyl)phenoxy...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 24 | n/a | n/a | n/a | n/a | n/a | n/a |
7TM Pharma Curated by ChEMBL | Assay Description Antagonist activity against CRTH2 receptor measured as inhibition of PGD2-induced beta-arrestin translocation in HEK293 cells by BRET assay | J Med Chem 49: 6638-41 (2006) Article DOI: 10.1021/jm060657g BindingDB Entry DOI: 10.7270/Q2DF6QV0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin D2 receptor 2 (Homo sapiens (Human)) | BDBM50200262 (4-bromo-2-[1-(3-bromophenyl)-1H-pyrazole-4-carbony...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 31 | n/a | n/a | n/a | n/a | n/a | n/a |
7TM Pharma Curated by ChEMBL | Assay Description Antagonist activity against CRTH2 receptor measured as inhibition of PGD2-induced beta-arrestin translocation in HEK293 cells by BRET assay | J Med Chem 49: 6638-41 (2006) Article DOI: 10.1021/jm060657g BindingDB Entry DOI: 10.7270/Q2DF6QV0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin D2 receptor 2 (Homo sapiens (Human)) | BDBM50200259 (CHEMBL217624 | [4'-chloro-3-(1-phenyl-1H-pyrazole-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 37 | n/a | n/a | n/a | n/a | n/a | n/a |
7TM Pharma Curated by ChEMBL | Assay Description Displacement of [3H]PGD2 from human CRTH2 receptor expressed in HEK293 cells | J Med Chem 49: 6638-41 (2006) Article DOI: 10.1021/jm060657g BindingDB Entry DOI: 10.7270/Q2DF6QV0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin D2 receptor 2 (Homo sapiens (Human)) | BDBM50200255 (3-(1-phenyl-1H-pyrazole-4-carbonyl)biphenyl-4-ylox...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 42 | n/a | n/a | n/a | n/a | n/a | n/a |
7TM Pharma Curated by ChEMBL | Assay Description Displacement of [3H]PGD2 from human CRTH2 receptor expressed in HEK293 cells | J Med Chem 49: 6638-41 (2006) Article DOI: 10.1021/jm060657g BindingDB Entry DOI: 10.7270/Q2DF6QV0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin D2 receptor 2 (Homo sapiens (Human)) | BDBM50200277 (4-nitro-2-(1-phenyl-1H-pyrazole-4-carbonyl)phenoxy...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 47 | n/a | n/a | n/a | n/a | n/a | n/a |
7TM Pharma Curated by ChEMBL | Assay Description Displacement of [3H]PGD2 from human CRTH2 receptor expressed in HEK293 cells | J Med Chem 49: 6638-41 (2006) Article DOI: 10.1021/jm060657g BindingDB Entry DOI: 10.7270/Q2DF6QV0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin D2 receptor 2 (Homo sapiens (Human)) | BDBM50200273 (4-methyl-2-(1-phenyl-1H-pyrazole-4-carbonyl)phenox...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 48 | n/a | n/a | n/a | n/a | n/a | n/a |
7TM Pharma Curated by ChEMBL | Assay Description Displacement of [3H]PGD2 from human CRTH2 receptor expressed in HEK293 cells | J Med Chem 49: 6638-41 (2006) Article DOI: 10.1021/jm060657g BindingDB Entry DOI: 10.7270/Q2DF6QV0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin D2 receptor 2 (Homo sapiens (Human)) | BDBM50200247 (4-bromo-2-[1-(4-methoxyphenyl)-1H-pyrazole-4-carbo...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 53 | n/a | n/a | n/a | n/a | n/a | n/a |
7TM Pharma Curated by ChEMBL | Assay Description Antagonist activity against CRTH2 receptor measured as inhibition of PGD2-induced beta-arrestin translocation in HEK293 cells by BRET assay | J Med Chem 49: 6638-41 (2006) Article DOI: 10.1021/jm060657g BindingDB Entry DOI: 10.7270/Q2DF6QV0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin D2 receptor 2 (Homo sapiens (Human)) | BDBM50200254 (2-(2-benzoyl-4-bromophenoxy)acetic acid | CHEMBL21...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 53 | n/a | n/a | n/a | n/a | n/a | n/a |
7TM Pharma Curated by ChEMBL | Assay Description Displacement of [3H]PGD2 from human CRTH2 receptor expressed in HEK293 cells | J Med Chem 49: 6638-41 (2006) Article DOI: 10.1021/jm060657g BindingDB Entry DOI: 10.7270/Q2DF6QV0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin D2 receptor 2 (Homo sapiens (Human)) | BDBM50200276 (CHEMBL217167 | {4-bromo-2-[(quinolin-8-ylhydrazono...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 54 | n/a | n/a | n/a | n/a | n/a | n/a |
7TM Pharma Curated by ChEMBL | Assay Description Displacement of [3H]PGD2 from human CRTH2 receptor expressed in HEK293 cells | J Med Chem 49: 6638-41 (2006) Article DOI: 10.1021/jm060657g BindingDB Entry DOI: 10.7270/Q2DF6QV0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin D2 receptor 2 (Homo sapiens (Human)) | BDBM50200269 (2-(4-bromo-2-tert-butylphenoxy)acetic acid | CHEMB...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 61 | n/a | n/a | n/a | n/a | n/a | n/a |
7TM Pharma Curated by ChEMBL | Assay Description Displacement of [3H]PGD2 from human CRTH2 receptor expressed in HEK293 cells | J Med Chem 49: 6638-41 (2006) Article DOI: 10.1021/jm060657g BindingDB Entry DOI: 10.7270/Q2DF6QV0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin D2 receptor 2 (Homo sapiens (Human)) | BDBM50200264 ((4-bromo-2-{[(5-phenyl-1,2,4-triazin-3-yl)hydrazon...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 89 | n/a | n/a | n/a | n/a | n/a | n/a |
7TM Pharma Curated by ChEMBL | Assay Description Displacement of [3H]PGD2 from human CRTH2 receptor expressed in HEK293 cells | J Med Chem 49: 6638-41 (2006) Article DOI: 10.1021/jm060657g BindingDB Entry DOI: 10.7270/Q2DF6QV0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin D2 receptor 2 (Homo sapiens (Human)) | BDBM50200256 (4-fluoro-2-(1-phenyl-1H-pyrazole-4-carbonyl)phenox...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 108 | n/a | n/a | n/a | n/a | n/a | n/a |
7TM Pharma Curated by ChEMBL | Assay Description Displacement of [3H]PGD2 from human CRTH2 receptor expressed in HEK293 cells | J Med Chem 49: 6638-41 (2006) Article DOI: 10.1021/jm060657g BindingDB Entry DOI: 10.7270/Q2DF6QV0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin D2 receptor 2 (Homo sapiens (Human)) | BDBM50200251 (2-(4-bromo-2-formylphenoxy)acetic acid | CHEMBL385...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 124 | n/a | n/a | n/a | n/a | n/a | n/a |
7TM Pharma Curated by ChEMBL | Assay Description Displacement of [3H]PGD2 from human CRTH2 receptor expressed in HEK293 cells | J Med Chem 49: 6638-41 (2006) Article DOI: 10.1021/jm060657g BindingDB Entry DOI: 10.7270/Q2DF6QV0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin D2 receptor 2 (Homo sapiens (Human)) | BDBM50200267 (CHEMBL214668 | [3',5'-difluoro-3-(1-phenyl-1H-pyra...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 147 | n/a | n/a | n/a | n/a | n/a | n/a |
7TM Pharma Curated by ChEMBL | Assay Description Antagonist activity against CRTH2 receptor measured as inhibition of PGD2-induced beta-arrestin translocation in HEK293 cells by BRET assay | J Med Chem 49: 6638-41 (2006) Article DOI: 10.1021/jm060657g BindingDB Entry DOI: 10.7270/Q2DF6QV0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin D2 receptor 2 (Homo sapiens (Human)) | BDBM50200268 (4-methoxy-2-(1-phenyl-1H-pyrazole-4-carbonyl)pheno...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 151 | n/a | n/a | n/a | n/a | n/a | n/a |
7TM Pharma Curated by ChEMBL | Assay Description Displacement of [3H]PGD2 from human CRTH2 receptor expressed in HEK293 cells | J Med Chem 49: 6638-41 (2006) Article DOI: 10.1021/jm060657g BindingDB Entry DOI: 10.7270/Q2DF6QV0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin D2 receptor 2 (Homo sapiens (Human)) | BDBM50200275 (CHEMBL216366 | ethyl 4-bromo-2-(1-phenyl-1H-pyrazo...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 165 | n/a | n/a | n/a | n/a | n/a | n/a |
7TM Pharma Curated by ChEMBL | Assay Description Displacement of [3H]PGD2 from human CRTH2 receptor expressed in HEK293 cells | J Med Chem 49: 6638-41 (2006) Article DOI: 10.1021/jm060657g BindingDB Entry DOI: 10.7270/Q2DF6QV0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin D2 receptor 2 (Homo sapiens (Human)) | BDBM50200270 (4-chloro-2-(1-phenyl-1H-pyrazole-4-carbonyl)phenox...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 185 | n/a | n/a | n/a | n/a | n/a | n/a |
7TM Pharma Curated by ChEMBL | Assay Description Antagonist activity against CRTH2 receptor measured as inhibition of PGD2-induced beta-arrestin translocation in HEK293 cells by BRET assay | J Med Chem 49: 6638-41 (2006) Article DOI: 10.1021/jm060657g BindingDB Entry DOI: 10.7270/Q2DF6QV0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin D2 receptor 2 (Homo sapiens (Human)) | BDBM50200277 (4-nitro-2-(1-phenyl-1H-pyrazole-4-carbonyl)phenoxy...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 236 | n/a | n/a | n/a | n/a | n/a | n/a |
7TM Pharma Curated by ChEMBL | Assay Description Antagonist activity against CRTH2 receptor measured as inhibition of PGD2-induced beta-arrestin translocation in HEK293 cells by BRET assay | J Med Chem 49: 6638-41 (2006) Article DOI: 10.1021/jm060657g BindingDB Entry DOI: 10.7270/Q2DF6QV0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin D2 receptor 2 (Homo sapiens (Human)) | BDBM50200272 (CHEMBL386358 | {4-bromo-2-[(pyridin-2-ylhydrazono)...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 255 | n/a | n/a | n/a | n/a | n/a | n/a |
7TM Pharma Curated by ChEMBL | Assay Description Displacement of [3H]PGD2 from human CRTH2 receptor expressed in HEK293 cells | J Med Chem 49: 6638-41 (2006) Article DOI: 10.1021/jm060657g BindingDB Entry DOI: 10.7270/Q2DF6QV0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin D2 receptor 2 (Homo sapiens (Human)) | BDBM50200249 (2-(4-bromo-2-(isoxazole-5-carbonyl)phenoxy)acetic ...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 391 | n/a | n/a | n/a | n/a | n/a | n/a |
7TM Pharma Curated by ChEMBL | Assay Description Displacement of [3H]PGD2 from human CRTH2 receptor expressed in HEK293 cells | J Med Chem 49: 6638-41 (2006) Article DOI: 10.1021/jm060657g BindingDB Entry DOI: 10.7270/Q2DF6QV0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin D2 receptor 2 (Homo sapiens (Human)) | BDBM50200269 (2-(4-bromo-2-tert-butylphenoxy)acetic acid | CHEMB...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 423 | n/a | n/a | n/a | n/a | n/a | n/a |
7TM Pharma Curated by ChEMBL | Assay Description Antagonist activity against CRTH2 receptor measured as inhibition of PGD2-induced beta-arrestin translocation in HEK293 cells by BRET assay | J Med Chem 49: 6638-41 (2006) Article DOI: 10.1021/jm060657g BindingDB Entry DOI: 10.7270/Q2DF6QV0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin D2 receptor 2 (Homo sapiens (Human)) | BDBM50200254 (2-(2-benzoyl-4-bromophenoxy)acetic acid | CHEMBL21...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 437 | n/a | n/a | n/a | n/a | n/a | n/a |
7TM Pharma Curated by ChEMBL | Assay Description Antagonist activity against CRTH2 receptor measured as inhibition of PGD2-induced beta-arrestin translocation in HEK293 cells by BRET assay | J Med Chem 49: 6638-41 (2006) Article DOI: 10.1021/jm060657g BindingDB Entry DOI: 10.7270/Q2DF6QV0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin D2 receptor 2 (Homo sapiens (Human)) | BDBM50200259 (CHEMBL217624 | [4'-chloro-3-(1-phenyl-1H-pyrazole-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 448 | n/a | n/a | n/a | n/a | n/a | n/a |
7TM Pharma Curated by ChEMBL | Assay Description Antagonist activity against CRTH2 receptor measured as inhibition of PGD2-induced beta-arrestin translocation in HEK293 cells by BRET assay | J Med Chem 49: 6638-41 (2006) Article DOI: 10.1021/jm060657g BindingDB Entry DOI: 10.7270/Q2DF6QV0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin D2 receptor 2 (Homo sapiens (Human)) | BDBM50200251 (2-(4-bromo-2-formylphenoxy)acetic acid | CHEMBL385...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 481 | n/a | n/a | n/a | n/a | n/a | n/a |
7TM Pharma Curated by ChEMBL | Assay Description Antagonist activity against CRTH2 receptor measured as inhibition of PGD2-induced beta-arrestin translocation in HEK293 cells by BRET assay | J Med Chem 49: 6638-41 (2006) Article DOI: 10.1021/jm060657g BindingDB Entry DOI: 10.7270/Q2DF6QV0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin D2 receptor 2 (Homo sapiens (Human)) | BDBM50200255 (3-(1-phenyl-1H-pyrazole-4-carbonyl)biphenyl-4-ylox...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 485 | n/a | n/a | n/a | n/a | n/a | n/a |
7TM Pharma Curated by ChEMBL | Assay Description Antagonist activity against CRTH2 receptor measured as inhibition of PGD2-induced beta-arrestin translocation in HEK293 cells by BRET assay | J Med Chem 49: 6638-41 (2006) Article DOI: 10.1021/jm060657g BindingDB Entry DOI: 10.7270/Q2DF6QV0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin D2 receptor 2 (Homo sapiens (Human)) | BDBM50200252 (2-(2-acetyl-4-bromophenoxy)acetic acid | CHEMBL384...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 510 | n/a | n/a | n/a | n/a | n/a | n/a |
7TM Pharma Curated by ChEMBL | Assay Description Displacement of [3H]PGD2 from human CRTH2 receptor expressed in HEK293 cells | J Med Chem 49: 6638-41 (2006) Article DOI: 10.1021/jm060657g BindingDB Entry DOI: 10.7270/Q2DF6QV0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin D2 receptor 2 (Homo sapiens (Human)) | BDBM50200258 (2-(1-phenyl-1H-pyrazole-4-carbonyl)phenoxyacetic a...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 510 | n/a | n/a | n/a | n/a | n/a | n/a |
7TM Pharma Curated by ChEMBL | Assay Description Displacement of [3H]PGD2 from human CRTH2 receptor expressed in HEK293 cells | J Med Chem 49: 6638-41 (2006) Article DOI: 10.1021/jm060657g BindingDB Entry DOI: 10.7270/Q2DF6QV0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin D2 receptor 2 (Homo sapiens (Human)) | BDBM50200263 (CHEMBL217709 | [2-({[(2,4-dichlorophenoxy)acetyl]h...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 555 | n/a | n/a | n/a | n/a | n/a | n/a |
7TM Pharma Curated by ChEMBL | Assay Description Displacement of [3H]PGD2 from human CRTH2 receptor expressed in HEK293 cells | J Med Chem 49: 6638-41 (2006) Article DOI: 10.1021/jm060657g BindingDB Entry DOI: 10.7270/Q2DF6QV0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin D2 receptor 2 (Homo sapiens (Human)) | BDBM50200273 (4-methyl-2-(1-phenyl-1H-pyrazole-4-carbonyl)phenox...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 587 | n/a | n/a | n/a | n/a | n/a | n/a |
7TM Pharma Curated by ChEMBL | Assay Description Antagonist activity against CRTH2 receptor measured as inhibition of PGD2-induced beta-arrestin translocation in HEK293 cells by BRET assay | J Med Chem 49: 6638-41 (2006) Article DOI: 10.1021/jm060657g BindingDB Entry DOI: 10.7270/Q2DF6QV0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin D2 receptor 2 (Homo sapiens (Human)) | BDBM50200276 (CHEMBL217167 | {4-bromo-2-[(quinolin-8-ylhydrazono...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | Article PubMed | n/a | n/a | 643 | n/a | n/a | n/a | n/a | n/a | n/a |
7TM Pharma Curated by ChEMBL | Assay Description Antagonist activity against CRTH2 receptor measured as inhibition of PGD2-induced beta-arrestin translocation in HEK293 cells by BRET assay | J Med Chem 49: 6638-41 (2006) Article DOI: 10.1021/jm060657g BindingDB Entry DOI: 10.7270/Q2DF6QV0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin D2 receptor 2 (Homo sapiens (Human)) | BDBM50200250 (2-(4-bromo-2-(hydroxymethyl)phenoxy)acetic acid | ...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 886 | n/a | n/a | n/a | n/a | n/a | n/a |
7TM Pharma Curated by ChEMBL | Assay Description Displacement of [3H]PGD2 from human CRTH2 receptor expressed in HEK293 cells | J Med Chem 49: 6638-41 (2006) Article DOI: 10.1021/jm060657g BindingDB Entry DOI: 10.7270/Q2DF6QV0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostaglandin D2 receptor 2 (Homo sapiens (Human)) | BDBM50200256 (4-fluoro-2-(1-phenyl-1H-pyrazole-4-carbonyl)phenox...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.32E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
7TM Pharma Curated by ChEMBL | Assay Description Antagonist activity against CRTH2 receptor measured as inhibition of PGD2-induced beta-arrestin translocation in HEK293 cells by BRET assay | J Med Chem 49: 6638-41 (2006) Article DOI: 10.1021/jm060657g BindingDB Entry DOI: 10.7270/Q2DF6QV0 | |||||||||||
More data for this Ligand-Target Pair |
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