Compile Data Set for Download or QSAR

Found 804 hits with Last Name = 'groll' and Initial = 'm'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50430967 (CHEMBL2337848) Show SMILES CC[C@H](C)C(=O)C(=O)N[C@H]1Cc2ccc(O)c(c2)-c2cccc3c2NC(=O)[C@@]3(O)[C@H](O)[C@H](NC(=O)[C@H](CC(N)=O)CC1=O)C(=O)N\C=C/C |r| Show InChI InChI=1S/C34H39N5O10/c1-4-11-36-31(46)27-29(44)34(49)21-8-6-7-19(26(21)39-33(34)48)20-12-17(9-10-23(20)40)13-22(37-32(47)28(43)16(3)5-2)24(41)14-18(15-25(35)42)30(45)38-27/h4,6-12,16,18,22,27,29,40,44,49H,5,13-15H2,1-3H3,(H2,35,42)(H,36,46)(H,37,47)(H,38,45)(H,39,48)/b11-4-/t16-,18-,22-,27-,29+,34-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	2.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University Paris 6 Curated by ChEMBL					Assay Description Competitive inhibition of chymotrypsin-like activity of human constitutive 20s proteasome beta-5 subunit using Suc-LLVY-AMC as substrate assessed as ...				J Med Chem 56: 3367-78 (2013) Article DOI: 10.1021/jm4002007 BindingDB Entry DOI: 10.7270/Q2F19135
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50430968 (CHEMBL2337847) Show SMILES C[C@H](NC(=O)[C@H](Cc1ccc(OCc2ccccc2)cc1)NC(=O)CCCCCNC(=O)CCCCCNC(=O)CCCCCNC(=O)CCCCCNC(=O)CCCCC(=O)NCCCCCC(=O)NCCCCCC(=O)NCCCCCC(=O)NCCCCCC(=O)N[C@@H](Cc1ccc(OCc2ccccc2)cc1)C(=O)N[C@@H](C)C(=O)N[C@@H](C[C@]1(O)C(=O)Nc2ccccc12)C(=O)NCc1ccccc1)C(=O)N[C@@H](C[C@]1(O)C(=O)Nc2ccccc12)C(=O)NCc1ccccc1 |r| Show InChI InChI=1S/C128H172N18O22/c1-91(119(157)143-107(121(159)137-87-95-45-15-3-16-46-95)85-127(165)101-53-31-33-55-103(101)145-125(127)163)139-123(161)105(83-93-67-71-99(72-68-93)167-89-97-49-19-5-20-50-97)141-117(155)65-29-13-43-81-133-113(151)61-25-9-39-77-129-109(147)57-23-7-37-75-131-111(149)59-27-11-41-79-135-115(153)63-35-36-64-116(154)136-80-42-12-28-60-112(150)132-76-38-8-24-58-110(148)130-78-40-10-26-62-114(152)134-82-44-14-30-66-118(156)142-106(84-94-69-73-100(74-70-94)168-90-98-51-21-6-22-52-98)124(162)140-92(2)120(158)144-108(122(160)138-88-96-47-17-4-18-48-96)86-128(166)102-54-32-34-56-104(102)146-126(128)164/h3-6,15-22,31-34,45-56,67-74,91-92,105-108,165-166H,7-14,23-30,35-44,57-66,75-90H2,1-2H3,(H,129,147)(H,130,148)(H,131,149)(H,132,150)(H,133,151)(H,134,152)(H,135,153)(H,136,154)(H,137,159)(H,138,160)(H,139,161)(H,140,162)(H,141,155)(H,142,156)(H,143,157)(H,144,158)(H,145,163)(H,146,164)/t91-,92-,105-,106-,107-,108-,127+,128+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University Paris 6 Curated by ChEMBL					Assay Description Competitive inhibition of chymotrypsin-like activity of human constitutive 20s proteasome beta-5 subunit using Suc-LLVY-AMC as substrate assessed as ...				J Med Chem 56: 3367-78 (2013) Article DOI: 10.1021/jm4002007 BindingDB Entry DOI: 10.7270/Q2F19135
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50430962 (CHEMBL2337843) Show SMILES C[C@H](NC(=O)[C@H](Cc1ccc(OCc2ccccc2)cc1)NC(=O)CCCCCNC(=O)CCCCCNC(=O)CCCCCNC(=O)CCCCC(=O)N[C@@H](Cc1ccc(OCc2ccccc2)cc1)C(=O)N[C@@H](C)C(=O)N[C@@H](C[C@]1(O)C(=O)Nc2ccccc12)C(=O)NCc1ccccc1)C(=O)N[C@@H](C[C@]1(O)C(=O)Nc2ccccc12)C(=O)NCc1ccccc1 |r| Show InChI InChI=1S/C98H117N13O17/c1-66(89(117)108-82(91(119)102-62-70-30-10-3-11-31-70)60-97(125)76-38-21-23-40-78(76)110-95(97)123)104-93(121)80(58-68-47-51-74(52-48-68)127-64-72-34-14-5-15-35-72)106-87(115)45-20-9-29-57-100-85(113)43-18-7-27-55-99-84(112)42-19-8-28-56-101-86(114)44-25-26-46-88(116)107-81(59-69-49-53-75(54-50-69)128-65-73-36-16-6-17-37-73)94(122)105-67(2)90(118)109-83(92(120)103-63-71-32-12-4-13-33-71)61-98(126)77-39-22-24-41-79(77)111-96(98)124/h3-6,10-17,21-24,30-41,47-54,66-67,80-83,125-126H,7-9,18-20,25-29,42-46,55-65H2,1-2H3,(H,99,112)(H,100,113)(H,101,114)(H,102,119)(H,103,120)(H,104,121)(H,105,122)(H,106,115)(H,107,116)(H,108,117)(H,109,118)(H,110,123)(H,111,124)/t66-,67-,80-,81-,82-,83-,97+,98+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University Paris 6 Curated by ChEMBL					Assay Description Competitive inhibition of chymotrypsin-like activity of human constitutive 20s proteasome beta-5 subunit using Suc-LLVY-AMC as substrate assessed as ...				J Med Chem 56: 3367-78 (2013) Article DOI: 10.1021/jm4002007 BindingDB Entry DOI: 10.7270/Q2F19135
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50430969 (CHEMBL2337846) Show SMILES C[C@H](NC(=O)[C@H](Cc1ccc(OCc2ccccc2)cc1)NC(=O)CCCCCNC(=O)CCCCCNC(=O)CCCCCNC(=O)CCCCC(=O)NCCCCCC(=O)NCCCCCC(=O)NCCCCCC(=O)N[C@@H](Cc1ccc(OCc2ccccc2)cc1)C(=O)N[C@@H](C)C(=O)N[C@@H](C[C@]1(O)C(=O)Nc2ccccc12)C(=O)NCc1ccccc1)C(=O)N[C@@H](C[C@]1(O)C(=O)Nc2ccccc12)C(=O)NCc1ccccc1 |r| Show InChI InChI=1S/C116H150N16O20/c1-81(107(141)129-97(109(143)123-77-85-39-13-3-14-40-85)75-115(149)91-47-27-29-49-93(91)131-113(115)147)125-111(145)95(73-83-59-63-89(64-60-83)151-79-87-43-17-5-18-44-87)127-105(139)57-25-11-37-71-119-101(135)53-21-7-33-67-117-99(133)51-23-9-35-69-121-103(137)55-31-32-56-104(138)122-70-36-10-24-52-100(134)118-68-34-8-22-54-102(136)120-72-38-12-26-58-106(140)128-96(74-84-61-65-90(66-62-84)152-80-88-45-19-6-20-46-88)112(146)126-82(2)108(142)130-98(110(144)124-78-86-41-15-4-16-42-86)76-116(150)92-48-28-30-50-94(92)132-114(116)148/h3-6,13-20,27-30,39-50,59-66,81-82,95-98,149-150H,7-12,21-26,31-38,51-58,67-80H2,1-2H3,(H,117,133)(H,118,134)(H,119,135)(H,120,136)(H,121,137)(H,122,138)(H,123,143)(H,124,144)(H,125,145)(H,126,146)(H,127,139)(H,128,140)(H,129,141)(H,130,142)(H,131,147)(H,132,148)/t81-,82-,95-,96-,97-,98-,115+,116+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University Paris 6 Curated by ChEMBL					Assay Description Competitive inhibition of chymotrypsin-like activity of human constitutive 20s proteasome beta-5 subunit using Suc-LLVY-AMC as substrate assessed as ...				J Med Chem 56: 3367-78 (2013) Article DOI: 10.1021/jm4002007 BindingDB Entry DOI: 10.7270/Q2F19135
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50430961 (CHEMBL2337844) Show SMILES C[C@H](NC(=O)[C@H](Cc1ccc(OCc2ccccc2)cc1)NC(=O)CCCCCNC(=O)CCCCCNC(=O)CCCCCNC(=O)CCCCCNC(=O)CCCCC(=O)N[C@@H](Cc1ccc(OCc2ccccc2)cc1)C(=O)N[C@@H](C)C(=O)N[C@@H](C[C@]1(O)C(=O)Nc2ccccc12)C(=O)NCc1ccccc1)C(=O)N[C@@H](C[C@]1(O)C(=O)Nc2ccccc12)C(=O)NCc1ccccc1 |r| Show InChI InChI=1S/C104H128N14O18/c1-71(95(125)115-87(97(127)109-67-75-33-11-3-12-34-75)65-103(133)81-41-23-25-43-83(81)117-101(103)131)111-99(129)85(63-73-51-55-79(56-52-73)135-69-77-37-15-5-16-38-77)113-93(123)49-22-10-32-62-107-91(121)47-20-8-30-60-105-89(119)45-19-7-29-59-106-90(120)46-21-9-31-61-108-92(122)48-27-28-50-94(124)114-86(64-74-53-57-80(58-54-74)136-70-78-39-17-6-18-40-78)100(130)112-72(2)96(126)116-88(98(128)110-68-76-35-13-4-14-36-76)66-104(134)82-42-24-26-44-84(82)118-102(104)132/h3-6,11-18,23-26,33-44,51-58,71-72,85-88,133-134H,7-10,19-22,27-32,45-50,59-70H2,1-2H3,(H,105,119)(H,106,120)(H,107,121)(H,108,122)(H,109,127)(H,110,128)(H,111,129)(H,112,130)(H,113,123)(H,114,124)(H,115,125)(H,116,126)(H,117,131)(H,118,132)/t71-,72-,85-,86-,87-,88-,103+,104+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University Paris 6 Curated by ChEMBL					Assay Description Competitive inhibition of chymotrypsin-like activity of human constitutive 20s proteasome beta-5 subunit using Suc-LLVY-AMC as substrate assessed as ...				J Med Chem 56: 3367-78 (2013) Article DOI: 10.1021/jm4002007 BindingDB Entry DOI: 10.7270/Q2F19135
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50430970 (CHEMBL2337845) Show SMILES C[C@H](NC(=O)[C@H](Cc1ccc(OCc2ccccc2)cc1)NC(=O)CCCCCNC(=O)CCCCCNC(=O)CCCCCNC(=O)CCCCCNC(=O)CCCCCNC(=O)CCCCC(=O)N[C@@H](Cc1ccc(OCc2ccccc2)cc1)C(=O)N[C@@H](C)C(=O)N[C@@H](C[C@]1(O)C(=O)Nc2ccccc12)C(=O)NCc1ccccc1)C(=O)N[C@@H](C[C@]1(O)C(=O)Nc2ccccc12)C(=O)NCc1ccccc1 |r| Show InChI InChI=1S/C110H139N15O19/c1-76(101(133)122-92(103(135)116-72-80-36-12-3-13-37-80)70-109(141)86-44-25-27-46-88(86)124-107(109)139)118-105(137)90(68-78-55-59-84(60-56-78)143-74-82-40-16-5-17-41-82)120-99(131)53-24-11-35-67-114-97(129)51-22-9-33-65-112-95(127)49-20-7-31-63-111-94(126)48-21-8-32-64-113-96(128)50-23-10-34-66-115-98(130)52-29-30-54-100(132)121-91(69-79-57-61-85(62-58-79)144-75-83-42-18-6-19-43-83)106(138)119-77(2)102(134)123-93(104(136)117-73-81-38-14-4-15-39-81)71-110(142)87-45-26-28-47-89(87)125-108(110)140/h3-6,12-19,25-28,36-47,55-62,76-77,90-93,141-142H,7-11,20-24,29-35,48-54,63-75H2,1-2H3,(H,111,126)(H,112,127)(H,113,128)(H,114,129)(H,115,130)(H,116,135)(H,117,136)(H,118,137)(H,119,138)(H,120,131)(H,121,132)(H,122,133)(H,123,134)(H,124,139)(H,125,140)/t76-,77-,90-,91-,92-,93-,109+,110+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University Paris 6 Curated by ChEMBL					Assay Description Competitive inhibition of chymotrypsin-like activity of human constitutive 20s proteasome beta-5 subunit using Suc-LLVY-AMC as substrate assessed as ...				J Med Chem 56: 3367-78 (2013) Article DOI: 10.1021/jm4002007 BindingDB Entry DOI: 10.7270/Q2F19135
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50430963 (CHEMBL2337842) Show SMILES C[C@H](NC(=O)[C@H](Cc1ccc(OCc2ccccc2)cc1)NC(=O)CCCCCNC(=O)CCCCCNC(=O)CCCCCNC(=O)CCCCCNC(=O)OC(C)(C)C)C(=O)N[C@@H](C[C@]1(O)C(=O)Nc2ccccc12)C(=O)NCc1ccccc1 |r| Show InChI InChI=1S/C66H91N9O12/c1-47(60(80)74-55(61(81)71-45-49-25-11-5-12-26-49)44-66(85)52-29-19-20-30-53(52)75-63(66)83)72-62(82)54(43-48-35-37-51(38-36-48)86-46-50-27-13-6-14-28-50)73-59(79)34-18-10-23-41-69-57(77)32-16-8-21-39-67-56(76)31-15-7-22-40-68-58(78)33-17-9-24-42-70-64(84)87-65(2,3)4/h5-6,11-14,19-20,25-30,35-38,47,54-55,85H,7-10,15-18,21-24,31-34,39-46H2,1-4H3,(H,67,76)(H,68,78)(H,69,77)(H,70,84)(H,71,81)(H,72,82)(H,73,79)(H,74,80)(H,75,83)/t47-,54-,55-,66+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	67	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University Paris 6 Curated by ChEMBL					Assay Description Mixed type inhibition of chymotrypsin-like activity of human constitutive 20s proteasome beta-5 subunit using Suc-LLVY-AMC as substrate assessed as i...				J Med Chem 56: 3367-78 (2013) Article DOI: 10.1021/jm4002007 BindingDB Entry DOI: 10.7270/Q2F19135
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50430964 (CHEMBL2337841) Show SMILES C[C@H](NC(=O)[C@H](Cc1ccc(OCc2ccccc2)cc1)NC(=O)CCCCCNC(=O)CCCCCNC(=O)CCCCCNC(=O)OC(C)(C)C)C(=O)N[C@@H](C[C@]1(O)C(=O)Nc2ccccc12)C(=O)NCc1ccccc1 |r| Show InChI InChI=1S/C60H80N8O11/c1-42(54(72)67-50(55(73)64-40-44-22-10-5-11-23-44)39-60(77)47-26-17-18-27-48(47)68-57(60)75)65-56(74)49(38-43-31-33-46(34-32-43)78-41-45-24-12-6-13-25-45)66-53(71)30-16-9-20-36-62-51(69)28-14-7-19-35-61-52(70)29-15-8-21-37-63-58(76)79-59(2,3)4/h5-6,10-13,17-18,22-27,31-34,42,49-50,77H,7-9,14-16,19-21,28-30,35-41H2,1-4H3,(H,61,70)(H,62,69)(H,63,76)(H,64,73)(H,65,74)(H,66,71)(H,67,72)(H,68,75)/t42-,49-,50-,60+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	101	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University Paris 6 Curated by ChEMBL					Assay Description Mixed type inhibition of chymotrypsin-like activity of human constitutive 20s proteasome beta-5 subunit using Suc-LLVY-AMC as substrate assessed as i...				J Med Chem 56: 3367-78 (2013) Article DOI: 10.1021/jm4002007 BindingDB Entry DOI: 10.7270/Q2F19135
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50430963 (CHEMBL2337842) Show SMILES C[C@H](NC(=O)[C@H](Cc1ccc(OCc2ccccc2)cc1)NC(=O)CCCCCNC(=O)CCCCCNC(=O)CCCCCNC(=O)CCCCCNC(=O)OC(C)(C)C)C(=O)N[C@@H](C[C@]1(O)C(=O)Nc2ccccc12)C(=O)NCc1ccccc1 |r| Show InChI InChI=1S/C66H91N9O12/c1-47(60(80)74-55(61(81)71-45-49-25-11-5-12-26-49)44-66(85)52-29-19-20-30-53(52)75-63(66)83)72-62(82)54(43-48-35-37-51(38-36-48)86-46-50-27-13-6-14-28-50)73-59(79)34-18-10-23-41-69-57(77)32-16-8-21-39-67-56(76)31-15-7-22-40-68-58(78)33-17-9-24-42-70-64(84)87-65(2,3)4/h5-6,11-14,19-20,25-30,35-38,47,54-55,85H,7-10,15-18,21-24,31-34,39-46H2,1-4H3,(H,67,76)(H,68,78)(H,69,77)(H,70,84)(H,71,81)(H,72,82)(H,73,79)(H,74,80)(H,75,83)/t47-,54-,55-,66+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University Paris 6 Curated by ChEMBL					Assay Description Mixed type inhibition of chymotrypsin-like activity of human constitutive 20s proteasome beta-5 subunit using Suc-LLVY-AMC as substrate assessed as i...				J Med Chem 56: 3367-78 (2013) Article DOI: 10.1021/jm4002007 BindingDB Entry DOI: 10.7270/Q2F19135
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50430964 (CHEMBL2337841) Show SMILES C[C@H](NC(=O)[C@H](Cc1ccc(OCc2ccccc2)cc1)NC(=O)CCCCCNC(=O)CCCCCNC(=O)CCCCCNC(=O)OC(C)(C)C)C(=O)N[C@@H](C[C@]1(O)C(=O)Nc2ccccc12)C(=O)NCc1ccccc1 |r| Show InChI InChI=1S/C60H80N8O11/c1-42(54(72)67-50(55(73)64-40-44-22-10-5-11-23-44)39-60(77)47-26-17-18-27-48(47)68-57(60)75)65-56(74)49(38-43-31-33-46(34-32-43)78-41-45-24-12-6-13-25-45)66-53(71)30-16-9-20-36-62-51(69)28-14-7-19-35-61-52(70)29-15-8-21-37-63-58(76)79-59(2,3)4/h5-6,10-13,17-18,22-27,31-34,42,49-50,77H,7-9,14-16,19-21,28-30,35-41H2,1-4H3,(H,61,70)(H,62,69)(H,63,76)(H,64,73)(H,65,74)(H,66,71)(H,67,72)(H,68,75)/t42-,49-,50-,60+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	316	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University Paris 6 Curated by ChEMBL					Assay Description Mixed type inhibition of chymotrypsin-like activity of human constitutive 20s proteasome beta-5 subunit using Suc-LLVY-AMC as substrate assessed as i...				J Med Chem 56: 3367-78 (2013) Article DOI: 10.1021/jm4002007 BindingDB Entry DOI: 10.7270/Q2F19135
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50430966 (CHEMBL2337849) Show SMILES C[C@H](NC(=O)[C@H](Cc1ccc(OCc2ccccc2)cc1)NC(=O)OC(C)(C)C)C(=O)N[C@@H](C[C@]1(O)C(=O)Nc2ccccc12)C(=O)NCc1ccccc1 |r| Show InChI InChI=1S/C42H47N5O8/c1-27(36(48)45-35(37(49)43-25-29-13-7-5-8-14-29)24-42(53)32-17-11-12-18-33(32)46-39(42)51)44-38(50)34(47-40(52)55-41(2,3)4)23-28-19-21-31(22-20-28)54-26-30-15-9-6-10-16-30/h5-22,27,34-35,53H,23-26H2,1-4H3,(H,43,49)(H,44,50)(H,45,48)(H,46,51)(H,47,52)/t27-,34-,35-,42+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.43E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University Paris 6 Curated by ChEMBL					Assay Description Mixed type inhibition of chymotrypsin-like activity of human constitutive 20s proteasome beta-5 subunit using Suc-LLVY-AMC as substrate assessed as i...				J Med Chem 56: 3367-78 (2013) Article DOI: 10.1021/jm4002007 BindingDB Entry DOI: 10.7270/Q2F19135
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50430966 (CHEMBL2337849) Show SMILES C[C@H](NC(=O)[C@H](Cc1ccc(OCc2ccccc2)cc1)NC(=O)OC(C)(C)C)C(=O)N[C@@H](C[C@]1(O)C(=O)Nc2ccccc12)C(=O)NCc1ccccc1 |r| Show InChI InChI=1S/C42H47N5O8/c1-27(36(48)45-35(37(49)43-25-29-13-7-5-8-14-29)24-42(53)32-17-11-12-18-33(32)46-39(42)51)44-38(50)34(47-40(52)55-41(2,3)4)23-28-19-21-31(22-20-28)54-26-30-15-9-6-10-16-30/h5-22,27,34-35,53H,23-26H2,1-4H3,(H,43,49)(H,44,50)(H,45,48)(H,46,51)(H,47,52)/t27-,34-,35-,42+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.03E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University Paris 6 Curated by ChEMBL					Assay Description Mixed type inhibition of chymotrypsin-like activity of human constitutive 20s proteasome beta-5 subunit using Suc-LLVY-AMC as substrate assessed as i...				J Med Chem 56: 3367-78 (2013) Article DOI: 10.1021/jm4002007 BindingDB Entry DOI: 10.7270/Q2F19135
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50430965 (CHEMBL2337850) Show SMILES C[C@H](NC(=O)[C@@H](N)Cc1ccc(OCc2ccccc2)cc1)C(=O)N[C@@H](C[C@]1(O)C(=O)Nc2ccccc12)C(=O)NCc1ccccc1 |r| Show InChI InChI=1S/C37H39N5O6/c1-24(40-34(44)30(38)20-25-16-18-28(19-17-25)48-23-27-12-6-3-7-13-27)33(43)41-32(35(45)39-22-26-10-4-2-5-11-26)21-37(47)29-14-8-9-15-31(29)42-36(37)46/h2-19,24,30,32,47H,20-23,38H2,1H3,(H,39,45)(H,40,44)(H,41,43)(H,42,46)/t24-,30-,32-,37+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.45E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University Paris 6 Curated by ChEMBL					Assay Description Noncompetitive inhibition of chymotrypsin-like activity of human constitutive 20s proteasome beta-5 subunit using Suc-LLVY-AMC as substrate assessed ...				J Med Chem 56: 3367-78 (2013) Article DOI: 10.1021/jm4002007 BindingDB Entry DOI: 10.7270/Q2F19135
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50430965 (CHEMBL2337850) Show SMILES C[C@H](NC(=O)[C@@H](N)Cc1ccc(OCc2ccccc2)cc1)C(=O)N[C@@H](C[C@]1(O)C(=O)Nc2ccccc12)C(=O)NCc1ccccc1 |r| Show InChI InChI=1S/C37H39N5O6/c1-24(40-34(44)30(38)20-25-16-18-28(19-17-25)48-23-27-12-6-3-7-13-27)33(43)41-32(35(45)39-22-26-10-4-2-5-11-26)21-37(47)29-14-8-9-15-31(29)42-36(37)46/h2-19,24,30,32,47H,20-23,38H2,1H3,(H,39,45)(H,40,44)(H,41,43)(H,42,46)/t24-,30-,32-,37+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.45E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University Paris 6 Curated by ChEMBL					Assay Description Noncompetitive inhibition of chymotrypsin-like activity of human constitutive 20s proteasome beta-5 subunit using Suc-LLVY-AMC as substrate assessed ...				J Med Chem 56: 3367-78 (2013) Article DOI: 10.1021/jm4002007 BindingDB Entry DOI: 10.7270/Q2F19135
					More data for this Ligand-Target Pair
Proteasome subunit beta type-8 (Homo sapiens (Human))	BDBM50099832 (CHEMBL3319587) Show SMILES COc1ccc(C[C@H](NC(=O)[C@@H](C)NC(=O)CN2CCOCC2)C(=O)N[C@@H](Cc2ccc(cc2)-c2ccccc2)C(=O)[C@@]2(C)CO2)cc1 |r| Show InChI InChI=1S/C9H13NO3/c1-6-2-3-8(13-6)7(5-10)4-9(11)12/h2-3,7H,4-5,10H2,1H3,(H,11,12)/t7-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
Leiden Institute of Chemistry and Netherlands Proteomics Centre Curated by ChEMBL					Assay Description Inhibition of proteasome subunit beta-5i in human Raji cells using BODIPY-NC005 by fluorescent densitometry				J Med Chem 57: 6197-209 (2014) Article DOI: 10.1021/jm500716s BindingDB Entry DOI: 10.7270/Q2BR8TZT
					More data for this Ligand-Target Pair
Proteasome subunit alpha type-2 (Saccharomyces cerevisiae s288c (Yeast))	BDBM154579 ((2S)-2-[(2S)-2-hexanamido-3-methylbutanamido]-N,N-...) Show SMILES CCCCCC(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCC(=O)N(C)C)C(=O)N[C@@H](CC(C)C)C(=O)[C@@]1(C)CO1 |r| Show InChI InChI=1S/C27H48N4O6/c1-9-10-11-12-21(32)30-23(18(4)5)26(36)28-19(13-14-22(33)31(7)8)25(35)29-20(15-17(2)3)24(34)27(6)16-37-27/h17-20,23H,9-16H2,1-8H3,(H,28,36)(H,29,35)(H,30,32)/t19-,20-,23-,27+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20	n/a	n/a	n/a	n/a	7.5	n/a
University of California at San Diego; University of Campinas					Assay Description One nanomolar of proteasome was incubated with different inhibitor concentrations in Tris 25 mM pH 7.5; SDS 0.03%; EDTA 0.5 mM for 15 min at 37 °C in...				Chem Biol 21: 782-91 (2014) Article DOI: 10.1016/j.chembiol.2014.04.010 BindingDB Entry DOI: 10.7270/Q2QR4VVS
					More data for this Ligand-Target Pair
Proteasome subunit beta type-8 (Homo sapiens (Human))	BDBM50099830 (CHEMBL3319585) Show SMILES COc1ccc(C[C@H](NC(=O)[C@H](C)NC(=O)C2=C(C)c3ccccc3C2)C(=O)N[C@@H](Cc2ccc(cc2)-c2ccccc2)C(=O)[C@@]2(C)CO2)cc1 |r,c:16| Show InChI InChI=1S/C8H11NO2S/c9-4-7(3-8(10)11)6-1-2-12-5-6/h1-2,5,7H,3-4,9H2,(H,10,11)/t7-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
Leiden Institute of Chemistry and Netherlands Proteomics Centre Curated by ChEMBL					Assay Description Inhibition of proteasome subunit beta-5i in human Raji cells using BODIPY-NC005 by fluorescent densitometry				J Med Chem 57: 6197-209 (2014) Article DOI: 10.1021/jm500716s BindingDB Entry DOI: 10.7270/Q2BR8TZT
					More data for this Ligand-Target Pair
Proteasome subunit alpha type-2 (Saccharomyces cerevisiae s288c (Yeast))	BDBM154578 (Carmaphycin A (1)) Show SMILES CCCCCC(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCS(C)=O)C(=O)N[C@@H](CC(C)C)C(=O)[C@@]1(C)CO1 |r| Show InChI InChI=1S/C25H45N3O6S/c1-8-9-10-11-20(29)28-21(17(4)5)24(32)26-18(12-13-35(7)33)23(31)27-19(14-16(2)3)22(30)25(6)15-34-25/h16-19,21H,8-15H2,1-7H3,(H,26,32)(H,27,31)(H,28,29)/t18-,19-,21-,25+,35?/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.5	n/a	n/a	n/a	n/a	7.5	n/a
University of California at San Diego; University of Campinas					Assay Description One nanomolar of proteasome was incubated with different inhibitor concentrations in Tris 25 mM pH 7.5; SDS 0.03%; EDTA 0.5 mM for 15 min at 37 °C in...				Chem Biol 21: 782-91 (2014) Article DOI: 10.1016/j.chembiol.2014.04.010 BindingDB Entry DOI: 10.7270/Q2QR4VVS
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50536438 (CHEMBL4534488) Show SMILES CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC1CCC(C)CC1)NC(=O)[C@H](Cc1ccccc1)N=[N+]=[N-])C(=O)[C@@]1(C)CO1 |r,wU:4.3,19.20,31.41,wD:8.8,44.47,(77.52,-2.76,;77.84,-4.19,;79.29,-4.35,;76.76,-5.18,;77.08,-6.61,;75.74,-7.37,;74.42,-6.61,;74.42,-5.06,;73.08,-7.37,;73.08,-8.91,;74.42,-9.69,;74.41,-11.23,;75.73,-12,;77.07,-11.23,;77.07,-9.68,;75.73,-8.91,;71.75,-6.61,;70.41,-7.37,;70.41,-8.91,;69.07,-6.61,;69.07,-5.06,;70.41,-4.29,;71.75,-5.07,;73.09,-4.3,;73.09,-2.76,;74.42,-1.99,;71.74,-1.99,;70.41,-2.76,;67.74,-7.37,;66.4,-6.61,;66.4,-5.06,;65.07,-7.37,;63.74,-6.61,;62.4,-7.37,;61.08,-6.61,;59.75,-7.37,;59.73,-8.91,;61.08,-9.69,;62.4,-8.91,;65.07,-8.91,;66.35,-9.77,;67.64,-10.62,;78.42,-7.37,;78.42,-8.91,;79.75,-6.6,;80.84,-7.68,;79.74,-5.06,;81.08,-5.82,)| Show InChI InChI=1S/C37H50N6O5/c1-24(2)19-29(33(44)37(4)23-48-37)39-34(45)30(20-26-11-7-5-8-12-26)40-35(46)31(21-28-17-15-25(3)16-18-28)41-36(47)32(42-43-38)22-27-13-9-6-10-14-27/h5-14,24-25,28-32H,15-23H2,1-4H3,(H,39,45)(H,40,46)(H,41,47)/t25?,28?,29-,30-,31-,32-,37+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Leiden Institute of Chemistry Curated by ChEMBL					Assay Description Inhibition of catalytic activity of constitutive proteasome 20s subunit beta5 in human Raji cells incubated for 1 hr by BODIPY(TMR)-NC-005-VS probe b...				J Med Chem 59: 7177-87 (2016) Article DOI: 10.1021/acs.jmedchem.6b00705 BindingDB Entry DOI: 10.7270/Q2Z60SJ2
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50536438 (CHEMBL4534488) Show SMILES CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC1CCC(C)CC1)NC(=O)[C@H](Cc1ccccc1)N=[N+]=[N-])C(=O)[C@@]1(C)CO1 |r,wU:4.3,19.20,31.41,wD:8.8,44.47,(77.52,-2.76,;77.84,-4.19,;79.29,-4.35,;76.76,-5.18,;77.08,-6.61,;75.74,-7.37,;74.42,-6.61,;74.42,-5.06,;73.08,-7.37,;73.08,-8.91,;74.42,-9.69,;74.41,-11.23,;75.73,-12,;77.07,-11.23,;77.07,-9.68,;75.73,-8.91,;71.75,-6.61,;70.41,-7.37,;70.41,-8.91,;69.07,-6.61,;69.07,-5.06,;70.41,-4.29,;71.75,-5.07,;73.09,-4.3,;73.09,-2.76,;74.42,-1.99,;71.74,-1.99,;70.41,-2.76,;67.74,-7.37,;66.4,-6.61,;66.4,-5.06,;65.07,-7.37,;63.74,-6.61,;62.4,-7.37,;61.08,-6.61,;59.75,-7.37,;59.73,-8.91,;61.08,-9.69,;62.4,-8.91,;65.07,-8.91,;66.35,-9.77,;67.64,-10.62,;78.42,-7.37,;78.42,-8.91,;79.75,-6.6,;80.84,-7.68,;79.74,-5.06,;81.08,-5.82,)| Show InChI InChI=1S/C37H50N6O5/c1-24(2)19-29(33(44)37(4)23-48-37)39-34(45)30(20-26-11-7-5-8-12-26)40-35(46)31(21-28-17-15-25(3)16-18-28)41-36(47)32(42-43-38)22-27-13-9-6-10-14-27/h5-14,24-25,28-32H,15-23H2,1-4H3,(H,39,45)(H,40,46)(H,41,47)/t25?,28?,29-,30-,31-,32-,37+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Leiden Institute of Chemistry Curated by ChEMBL					Assay Description Inhibition of catalytic activity of constitutive proteasome 20s subunit beta5 in human Raji cells incubated for 1 hr by BODIPY(TMR)-NC-005-VS probe b...				J Med Chem 59: 7177-87 (2016) Article DOI: 10.1021/acs.jmedchem.6b00705 BindingDB Entry DOI: 10.7270/Q2Z60SJ2
					More data for this Ligand-Target Pair
Proteasome subunit beta type-8 (Homo sapiens (Human))	BDBM50099659 (CHEMBL3319478) Show SMILES COc1ccc(C[C@H](NC(=O)[C@H](C)NC(=O)CN2CCOCC2)C(=O)N[C@@H](Cc2ccc(cc2)-c2ccccc2)C(=O)[C@@]2(C)CO2)cc1 |r| Show InChI InChI=1S/C22H11ClF2N2O/c23-17-6-2-4-8-20(17)27-21(12-9-14-5-1-3-7-18(14)25)26-19-11-10-15(24)13-16(19)22(27)28/h1-8,10-11,13H	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Leiden Institute of Chemistry and Netherlands Proteomics Centre Curated by ChEMBL					Assay Description Inhibition of proteasome subunit beta-5i in human Raji cells using BODIPY-NC005 by fluorescent densitometry				J Med Chem 57: 6197-209 (2014) Article DOI: 10.1021/jm500716s BindingDB Entry DOI: 10.7270/Q2BR8TZT
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50536429 (CHEMBL4581491) Show SMILES COC1CCC(C[C@H](NC(=O)[C@H](Cc2ccccc2)N=[N+]=[N-])C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](CC(C)C)C(=O)[C@@]2(C)CO2)CC1 |r,wU:36.38,7.6,11.19,wD:25.26,43.45,(73.47,-11.43,;73.47,-12.97,;72.14,-13.74,;72.13,-15.28,;70.8,-16.05,;69.47,-15.27,;68.13,-16.05,;68.13,-17.59,;66.79,-18.35,;65.46,-17.59,;65.46,-16.05,;64.13,-18.35,;62.79,-17.59,;61.46,-18.35,;60.13,-17.59,;58.8,-18.35,;58.79,-19.9,;60.14,-20.67,;61.46,-19.89,;64.13,-19.89,;65.41,-20.75,;66.69,-21.6,;69.47,-18.35,;69.47,-19.89,;70.8,-17.59,;72.14,-18.35,;72.14,-19.89,;73.47,-20.67,;73.46,-22.21,;74.79,-22.98,;76.13,-22.21,;76.12,-20.66,;74.79,-19.9,;73.47,-17.59,;73.47,-16.05,;74.8,-18.35,;76.14,-17.59,;75.82,-16.16,;76.89,-15.17,;76.58,-13.75,;78.45,-15.33,;77.47,-18.35,;77.47,-19.89,;78.8,-17.58,;79.9,-18.66,;78.8,-16.04,;80.14,-16.8,;69.46,-13.74,;70.79,-12.97,)| Show InChI InChI=1S/C37H50N6O6/c1-24(2)19-29(33(44)37(3)23-49-37)39-34(45)30(20-25-11-7-5-8-12-25)40-35(46)31(21-27-15-17-28(48-4)18-16-27)41-36(47)32(42-43-38)22-26-13-9-6-10-14-26/h5-14,24,27-32H,15-23H2,1-4H3,(H,39,45)(H,40,46)(H,41,47)/t27?,28?,29-,30-,31-,32-,37+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.10	n/a	n/a	n/a	n/a	n/a	n/a
Leiden Institute of Chemistry Curated by ChEMBL					Assay Description Inhibition of catalytic activity of constitutive proteasome 20s subunit beta5 in human Raji cells incubated for 1 hr by BODIPY(TMR)-NC-005-VS probe b...				J Med Chem 59: 7177-87 (2016) Article DOI: 10.1021/acs.jmedchem.6b00705 BindingDB Entry DOI: 10.7270/Q2Z60SJ2
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50536425 (CHEMBL4563298) Show SMILES COc1ccc(C[C@H](NC(=O)[C@H](Cc2ccccc2)N=[N+]=[N-])C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](CC(C)C)C(=O)[C@@]2(C)CO2)cc1 |r| Show InChI InChI=1S/C37H44N6O6/c1-24(2)19-29(33(44)37(3)23-49-37)39-34(45)30(20-25-11-7-5-8-12-25)40-35(46)31(21-27-15-17-28(48-4)18-16-27)41-36(47)32(42-43-38)22-26-13-9-6-10-14-26/h5-18,24,29-32H,19-23H2,1-4H3,(H,39,45)(H,40,46)(H,41,47)/t29-,30-,31-,32-,37+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.10	n/a	n/a	n/a	n/a	n/a	n/a
Leiden Institute of Chemistry Curated by ChEMBL					Assay Description Inhibition of catalytic activity of constitutive proteasome 20s subunit beta5 in human Raji cells incubated for 1 hr by BODIPY(TMR)-NC-005-VS probe b...				J Med Chem 59: 7177-87 (2016) Article DOI: 10.1021/acs.jmedchem.6b00705 BindingDB Entry DOI: 10.7270/Q2Z60SJ2
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50536429 (CHEMBL4581491) Show SMILES COC1CCC(C[C@H](NC(=O)[C@H](Cc2ccccc2)N=[N+]=[N-])C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](CC(C)C)C(=O)[C@@]2(C)CO2)CC1 |r,wU:36.38,7.6,11.19,wD:25.26,43.45,(73.47,-11.43,;73.47,-12.97,;72.14,-13.74,;72.13,-15.28,;70.8,-16.05,;69.47,-15.27,;68.13,-16.05,;68.13,-17.59,;66.79,-18.35,;65.46,-17.59,;65.46,-16.05,;64.13,-18.35,;62.79,-17.59,;61.46,-18.35,;60.13,-17.59,;58.8,-18.35,;58.79,-19.9,;60.14,-20.67,;61.46,-19.89,;64.13,-19.89,;65.41,-20.75,;66.69,-21.6,;69.47,-18.35,;69.47,-19.89,;70.8,-17.59,;72.14,-18.35,;72.14,-19.89,;73.47,-20.67,;73.46,-22.21,;74.79,-22.98,;76.13,-22.21,;76.12,-20.66,;74.79,-19.9,;73.47,-17.59,;73.47,-16.05,;74.8,-18.35,;76.14,-17.59,;75.82,-16.16,;76.89,-15.17,;76.58,-13.75,;78.45,-15.33,;77.47,-18.35,;77.47,-19.89,;78.8,-17.58,;79.9,-18.66,;78.8,-16.04,;80.14,-16.8,;69.46,-13.74,;70.79,-12.97,)| Show InChI InChI=1S/C37H50N6O6/c1-24(2)19-29(33(44)37(3)23-49-37)39-34(45)30(20-25-11-7-5-8-12-25)40-35(46)31(21-27-15-17-28(48-4)18-16-27)41-36(47)32(42-43-38)22-26-13-9-6-10-14-26/h5-14,24,27-32H,15-23H2,1-4H3,(H,39,45)(H,40,46)(H,41,47)/t27?,28?,29-,30-,31-,32-,37+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.10	n/a	n/a	n/a	n/a	n/a	n/a
Leiden Institute of Chemistry Curated by ChEMBL					Assay Description Inhibition of catalytic activity of constitutive proteasome 20s subunit beta5 in human Raji cells incubated for 1 hr by BODIPY(TMR)-NC-005-VS probe b...				J Med Chem 59: 7177-87 (2016) Article DOI: 10.1021/acs.jmedchem.6b00705 BindingDB Entry DOI: 10.7270/Q2Z60SJ2
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50536425 (CHEMBL4563298) Show SMILES COc1ccc(C[C@H](NC(=O)[C@H](Cc2ccccc2)N=[N+]=[N-])C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](CC(C)C)C(=O)[C@@]2(C)CO2)cc1 |r| Show InChI InChI=1S/C37H44N6O6/c1-24(2)19-29(33(44)37(3)23-49-37)39-34(45)30(20-25-11-7-5-8-12-25)40-35(46)31(21-27-15-17-28(48-4)18-16-27)41-36(47)32(42-43-38)22-26-13-9-6-10-14-26/h5-18,24,29-32H,19-23H2,1-4H3,(H,39,45)(H,40,46)(H,41,47)/t29-,30-,31-,32-,37+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.10	n/a	n/a	n/a	n/a	n/a	n/a
Leiden Institute of Chemistry Curated by ChEMBL					Assay Description Inhibition of catalytic activity of constitutive proteasome 20s subunit beta5 in human Raji cells incubated for 1 hr by BODIPY(TMR)-NC-005-VS probe b...				J Med Chem 59: 7177-87 (2016) Article DOI: 10.1021/acs.jmedchem.6b00705 BindingDB Entry DOI: 10.7270/Q2Z60SJ2
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50307481 ((S)-2-azido-N-((S)-1-((S)-1-((S)-4-methyl-1-((R)-2...) Show SMILES CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccccc1)N=[N+]=[N-])C(=O)[C@@]1(C)CO1 |r| Show InChI InChI=1S/C36H42N6O5/c1-24(2)19-28(32(43)36(3)23-47-36)38-33(44)29(20-25-13-7-4-8-14-25)39-34(45)30(21-26-15-9-5-10-16-26)40-35(46)31(41-42-37)22-27-17-11-6-12-18-27/h4-18,24,28-31H,19-23H2,1-3H3,(H,38,44)(H,39,45)(H,40,46)/t28-,29-,30-,31-,36+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.10	n/a	n/a	n/a	n/a	n/a	n/a
Leiden Institute of Chemistry Curated by ChEMBL					Assay Description Inhibition of catalytic activity of constitutive proteasome 20s subunit beta5 in human Raji cells incubated for 1 hr by BODIPY(TMR)-NC-005-VS probe b...				J Med Chem 59: 7177-87 (2016) Article DOI: 10.1021/acs.jmedchem.6b00705 BindingDB Entry DOI: 10.7270/Q2Z60SJ2
					More data for this Ligand-Target Pair
Proteasome subunit beta type-8 (Homo sapiens (Human))	BDBM50099831 (CHEMBL3319586) Show SMILES C[C@@H](NC(=O)CN1CCOCC1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](Cc1ccc(cc1)-c1ccccc1)C(=O)[C@@]1(C)CO1 |r| Show InChI InChI=1S/C8H10ClNO2S/c9-6-2-7(13-4-6)5(3-10)1-8(11)12/h2,4-5H,1,3,10H2,(H,11,12)/t5-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.10	n/a	n/a	n/a	n/a	n/a	n/a
Leiden Institute of Chemistry and Netherlands Proteomics Centre Curated by ChEMBL					Assay Description Inhibition of proteasome subunit beta-5i in human Raji cells using BODIPY-NC005 by fluorescent densitometry				J Med Chem 57: 6197-209 (2014) Article DOI: 10.1021/jm500716s BindingDB Entry DOI: 10.7270/Q2BR8TZT
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50307481 ((S)-2-azido-N-((S)-1-((S)-1-((S)-4-methyl-1-((R)-2...) Show SMILES CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccccc1)N=[N+]=[N-])C(=O)[C@@]1(C)CO1 |r| Show InChI InChI=1S/C36H42N6O5/c1-24(2)19-28(32(43)36(3)23-47-36)38-33(44)29(20-25-13-7-4-8-14-25)39-34(45)30(21-26-15-9-5-10-16-26)40-35(46)31(41-42-37)22-27-17-11-6-12-18-27/h4-18,24,28-31H,19-23H2,1-3H3,(H,38,44)(H,39,45)(H,40,46)/t28-,29-,30-,31-,36+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.10	n/a	n/a	n/a	n/a	n/a	n/a
Leiden Institute of Chemistry Curated by ChEMBL					Assay Description Inhibition of catalytic activity of constitutive proteasome 20s subunit beta5 in human Raji cells incubated for 1 hr by BODIPY(TMR)-NC-005-VS probe b...				J Med Chem 59: 7177-87 (2016) Article DOI: 10.1021/acs.jmedchem.6b00705 BindingDB Entry DOI: 10.7270/Q2Z60SJ2
					More data for this Ligand-Target Pair
Proteasome subunit beta type-8 (Homo sapiens (Human))	BDBM50099663 (CHEMBL3319482) Show SMILES C[C@@H](NC(=O)C1=C(C)c2ccccc2C1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](Cc1ccccc1)C(=O)[C@@]1(C)CO1 |r,c:5| Show InChI InChI=1S/C22H16ClF2N3O/c23-17-6-2-4-8-20(17)28-21(13-26-12-14-5-1-3-7-18(14)25)27-19-10-9-15(24)11-16(19)22(28)29/h1-11,26H,12-13H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.5	n/a	n/a	n/a	n/a	n/a	n/a
Leiden Institute of Chemistry and Netherlands Proteomics Centre Curated by ChEMBL					Assay Description Inhibition of proteasome subunit beta-5i in human Raji cells using BODIPY-NC005 by fluorescent densitometry				J Med Chem 57: 6197-209 (2014) Article DOI: 10.1021/jm500716s BindingDB Entry DOI: 10.7270/Q2BR8TZT
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50470540 (CHEMBL4282642) Show SMILES [H][C@]1([C@@H](C)CC)[C@@H](OC1=O)C(=O)NCC(=O)N[C@@H](C(C)C)C(=O)OCc1ccccc1 |r| Show InChI InChI=1S/C22H30N2O6/c1-5-14(4)17-19(30-21(17)27)20(26)23-11-16(25)24-18(13(2)3)22(28)29-12-15-9-7-6-8-10-15/h6-10,13-14,17-19H,5,11-12H2,1-4H3,(H,23,26)(H,24,25)/t14-,17-,18-,19+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.70	n/a	n/a	n/a	n/a	n/a	n/a
New Mexico Institute of Mining and Technology Curated by ChEMBL					Assay Description Inhibition of 20S proteasome beta5 subunit in human Jurkat cell lysate using Suc-LLVY-AMC as substrate pretreated for 30 mins followed by substrate a...				Eur J Med Chem 157: 962-977 (2018) Article DOI: 10.1016/j.ejmech.2018.08.052 BindingDB Entry DOI: 10.7270/Q2028V7T
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50536431 (CHEMBL4519899) Show SMILES CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCc1ccccc1)NC(=O)[C@H](Cc1ccccc1)N=[N+]=[N-])C(=O)[C@@]1(C)CO1 |r| Show InChI InChI=1S/C37H44N6O5/c1-25(2)21-30(33(44)37(3)24-48-37)40-35(46)31(22-27-15-9-5-10-16-27)41-34(45)29(20-19-26-13-7-4-8-14-26)39-36(47)32(42-43-38)23-28-17-11-6-12-18-28/h4-18,25,29-32H,19-24H2,1-3H3,(H,39,47)(H,40,46)(H,41,45)/t29-,30-,31-,32-,37+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Leiden Institute of Chemistry Curated by ChEMBL					Assay Description Inhibition of catalytic activity of constitutive proteasome 20s subunit beta5 in human Raji cells incubated for 1 hr by BODIPY(TMR)-NC-005-VS probe b...				J Med Chem 59: 7177-87 (2016) Article DOI: 10.1021/acs.jmedchem.6b00705 BindingDB Entry DOI: 10.7270/Q2Z60SJ2
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50536431 (CHEMBL4519899) Show SMILES CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCc1ccccc1)NC(=O)[C@H](Cc1ccccc1)N=[N+]=[N-])C(=O)[C@@]1(C)CO1 |r| Show InChI InChI=1S/C37H44N6O5/c1-25(2)21-30(33(44)37(3)24-48-37)40-35(46)31(22-27-15-9-5-10-16-27)41-34(45)29(20-19-26-13-7-4-8-14-26)39-36(47)32(42-43-38)23-28-17-11-6-12-18-28/h4-18,25,29-32H,19-24H2,1-3H3,(H,39,47)(H,40,46)(H,41,45)/t29-,30-,31-,32-,37+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Leiden Institute of Chemistry Curated by ChEMBL					Assay Description Inhibition of catalytic activity of constitutive proteasome 20s subunit beta5 in human Raji cells incubated for 1 hr by BODIPY(TMR)-NC-005-VS probe b...				J Med Chem 59: 7177-87 (2016) Article DOI: 10.1021/acs.jmedchem.6b00705 BindingDB Entry DOI: 10.7270/Q2Z60SJ2
					More data for this Ligand-Target Pair
Proteasome subunit beta type-8 (Homo sapiens (Human))	BDBM50099829 (CHEMBL3319584) Show SMILES COc1ccc(C[C@H](NC(=O)[C@@H](C)NC(=O)C2=C(C)c3ccccc3C2)C(=O)N[C@@H](Cc2ccccc2)C(=O)[C@@]2(C)CO2)cc1 |r,c:16| Show InChI InChI=1S/C8H11NO3/c9-5-6(4-8(10)11)7-2-1-3-12-7/h1-3,6H,4-5,9H2,(H,10,11)/t6-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Leiden Institute of Chemistry and Netherlands Proteomics Centre Curated by ChEMBL					Assay Description Inhibition of proteasome subunit beta-5i in human Raji cells using BODIPY-NC005 by fluorescent densitometry				J Med Chem 57: 6197-209 (2014) Article DOI: 10.1021/jm500716s BindingDB Entry DOI: 10.7270/Q2BR8TZT
					More data for this Ligand-Target Pair
Proteasome subunit beta type-8 (Homo sapiens (Human))	BDBM50099685 (CHEMBL3319578) Show SMILES COc1ccc(C[C@H](NC(=O)[C@H](C)NC(=O)C2=C(C)c3ccccc3C2)C(=O)N[C@@H](CC2CCCCC2)C(=O)[C@@]2(C)CO2)cc1 |r,c:16| Show InChI InChI=1S/C36H45N3O6/c1-22-28-13-9-8-12-26(28)20-29(22)34(42)37-23(2)33(41)39-31(19-25-14-16-27(44-4)17-15-25)35(43)38-30(32(40)36(3)21-45-36)18-24-10-6-5-7-11-24/h8-9,12-17,23-24,30-31H,5-7,10-11,18-21H2,1-4H3,(H,37,42)(H,38,43)(H,39,41)/t23-,30-,31-,36+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Leiden Institute of Chemistry and Netherlands Proteomics Centre Curated by ChEMBL					Assay Description Inhibition of proteasome subunit beta-5i in human Raji cells using BODIPY-NC005 by fluorescent densitometry				J Med Chem 57: 6197-209 (2014) Article DOI: 10.1021/jm500716s BindingDB Entry DOI: 10.7270/Q2BR8TZT
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50470557 (CHEMBL4290778) Show SMILES [H][C@]1([C@@H](C)CC)[C@@H](OC1=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](COCc1ccccc1)C(=O)OCc1ccccc1 |r| Show InChI InChI=1S/C30H38N2O7/c1-5-20(4)24-26(39-30(24)36)28(34)32-25(19(2)3)27(33)31-23(18-37-16-21-12-8-6-9-13-21)29(35)38-17-22-14-10-7-11-15-22/h6-15,19-20,23-26H,5,16-18H2,1-4H3,(H,31,33)(H,32,34)/t20-,23-,24-,25-,26+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.10	n/a	n/a	n/a	n/a	n/a	n/a
New Mexico Institute of Mining and Technology Curated by ChEMBL					Assay Description Inhibition of 20S proteasome beta5 subunit in human Jurkat cell lysate using Suc-LLVY-AMC as substrate pretreated for 30 mins followed by substrate a...				Eur J Med Chem 157: 962-977 (2018) Article DOI: 10.1016/j.ejmech.2018.08.052 BindingDB Entry DOI: 10.7270/Q2028V7T
					More data for this Ligand-Target Pair
Proteasome subunit beta type-8 (Homo sapiens (Human))	BDBM50099660 (CHEMBL3319479) Show SMILES COc1ccc(C[C@H](NC(=O)[C@H](C)NC(=O)CN2CCOCC2)C(=O)N[C@@H](Cc2ccc3ccccc3c2)C(=O)[C@@]2(C)CO2)cc1 |r| Show InChI InChI=1S/C23H16ClF2N3O2/c1-14(30)28(21-9-5-3-7-18(21)26)13-22-27-19-11-10-15(25)12-16(19)23(31)29(22)20-8-4-2-6-17(20)24/h2-12H,13H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.10	n/a	n/a	n/a	n/a	n/a	n/a
Leiden Institute of Chemistry and Netherlands Proteomics Centre Curated by ChEMBL					Assay Description Inhibition of proteasome subunit beta-5i in human Raji cells using BODIPY-NC005 by fluorescent densitometry				J Med Chem 57: 6197-209 (2014) Article DOI: 10.1021/jm500716s BindingDB Entry DOI: 10.7270/Q2BR8TZT
					More data for this Ligand-Target Pair
Proteasome subunit beta type-8 (Homo sapiens (Human))	BDBM50099833 (CHEMBL3319588) Show SMILES COc1ccc(C[C@H](NC(=O)[C@@H](C)NC(=O)C2=C(C)c3ccccc3C2)C(=O)N[C@@H](Cc2ccc(cc2)-c2ccccc2)C(=O)[C@@]2(C)CO2)cc1 |r,c:16| Show InChI InChI=1S/C8H10BrNO2S/c9-6-2-7(13-4-6)5(3-10)1-8(11)12/h2,4-5H,1,3,10H2,(H,11,12)/t5-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.30	n/a	n/a	n/a	n/a	n/a	n/a
Leiden Institute of Chemistry and Netherlands Proteomics Centre Curated by ChEMBL					Assay Description Inhibition of proteasome subunit beta-5i in human Raji cells using BODIPY-NC005 by fluorescent densitometry				J Med Chem 57: 6197-209 (2014) Article DOI: 10.1021/jm500716s BindingDB Entry DOI: 10.7270/Q2BR8TZT
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50470536 (CHEMBL4292798) Show SMILES [H][C@]1([C@@H](C)CC)[C@@H](OC1=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C(C)C)C(=O)NCc1ccccc1 |r| Show InChI InChI=1S/C25H37N3O5/c1-7-16(6)18-21(33-25(18)32)24(31)28-20(15(4)5)23(30)27-19(14(2)3)22(29)26-13-17-11-9-8-10-12-17/h8-12,14-16,18-21H,7,13H2,1-6H3,(H,26,29)(H,27,30)(H,28,31)/t16-,18-,19-,20-,21+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.60	n/a	n/a	n/a	n/a	n/a	n/a
New Mexico Institute of Mining and Technology Curated by ChEMBL					Assay Description Inhibition of 20S proteasome beta5 subunit in human Jurkat cell lysate using Suc-LLVY-AMC as substrate pretreated for 30 mins followed by substrate a...				Eur J Med Chem 157: 962-977 (2018) Article DOI: 10.1016/j.ejmech.2018.08.052 BindingDB Entry DOI: 10.7270/Q2028V7T
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50536442 (CHEMBL4570216) Show SMILES C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](C[C@H]1CC[C@@H](CC1)c1ccccc1)NC(=O)[C@H](Cc1ccccc1)N=[N+]=[N-])C(=O)[C@@]1(C)CO1 |r,wU:16.32,1.0,33.44,18.18,wD:5.5,46.50,21.25,(48.13,-36.86,;48.13,-38.19,;46.79,-38.97,;45.46,-38.19,;45.46,-36.65,;44.12,-38.97,;44.12,-40.51,;45.46,-41.29,;45.45,-42.83,;46.78,-43.6,;48.12,-42.83,;48.12,-41.28,;46.78,-40.51,;42.79,-38.19,;41.45,-38.97,;41.45,-40.51,;40.11,-38.2,;40.11,-36.65,;41.44,-35.88,;41.43,-34.35,;42.77,-33.58,;44.1,-34.35,;44.09,-35.89,;42.76,-36.65,;45.42,-33.59,;46.75,-34.37,;48.08,-33.61,;48.09,-32.07,;46.75,-31.3,;45.43,-32.06,;38.78,-38.97,;37.44,-38.19,;37.44,-36.65,;36.11,-38.97,;34.77,-38.19,;33.43,-38.97,;32.1,-38.2,;30.77,-38.97,;30.76,-40.51,;32.11,-41.29,;33.43,-40.51,;36.11,-40.51,;37.39,-41.37,;38.67,-42.22,;49.47,-38.97,;49.47,-40.51,;50.8,-38.19,;51.89,-39.28,;50.79,-36.64,;52.13,-37.41,)| Show InChI InChI=1S/C39H46N6O5/c1-26(35(46)39(2)25-50-39)41-36(47)32(22-27-12-6-3-7-13-27)42-37(48)33(23-29-18-20-31(21-19-29)30-16-10-5-11-17-30)43-38(49)34(44-45-40)24-28-14-8-4-9-15-28/h3-17,26,29,31-34H,18-25H2,1-2H3,(H,41,47)(H,42,48)(H,43,49)/t26-,29-,31-,32-,33-,34-,39+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.80	n/a	n/a	n/a	n/a	n/a	n/a
Leiden Institute of Chemistry Curated by ChEMBL					Assay Description Inhibition of catalytic activity of constitutive proteasome 20s subunit beta5 in human Raji cells incubated for 1 hr by BODIPY(TMR)-NC-005-VS probe b...				J Med Chem 59: 7177-87 (2016) Article DOI: 10.1021/acs.jmedchem.6b00705 BindingDB Entry DOI: 10.7270/Q2Z60SJ2
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50069989 ((R)-3-methyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxa...) Show SMILES CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)c1cnccn1)B(O)O |r| Show InChI InChI=1S/C19H25BN4O4/c1-13(2)10-17(20(27)28)24-18(25)15(11-14-6-4-3-5-7-14)23-19(26)16-12-21-8-9-22-16/h3-9,12-13,15,17,27-28H,10-11H2,1-2H3,(H,23,26)(H,24,25)/t15-,17-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	n/a	n/a	4.40	n/a	n/a	n/a	n/a	n/a	n/a
Heinrich Heine University D£sseldorf Curated by ChEMBL					Assay Description Inhibition of chymotrypsin-like activity of 20S proteasome in human SEM cells using Suc-LLVY aminoluciferin as substrate after 2 hrs by proteasome-Gl...				J Med Chem 61: 10299-10309 (2018) Article DOI: 10.1021/acs.jmedchem.8b01487 BindingDB Entry DOI: 10.7270/Q26W9DMW
					More data for this Ligand-Target Pair				3D Structure (crystal)
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50069989 ((R)-3-methyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxa...) Show SMILES CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)c1cnccn1)B(O)O |r| Show InChI InChI=1S/C19H25BN4O4/c1-13(2)10-17(20(27)28)24-18(25)15(11-14-6-4-3-5-7-14)23-19(26)16-12-21-8-9-22-16/h3-9,12-13,15,17,27-28H,10-11H2,1-2H3,(H,23,26)(H,24,25)/t15-,17-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	n/a	n/a	4.5	n/a	n/a	n/a	n/a	n/a	n/a
Hokkaido University Curated by ChEMBL					Assay Description Inhibition of chymotrypsin-like activity of human 20S proteasome beta 5 subunit using Suc-LLVY-AMC as substrate after 60 mins by fluorescence assay				J Med Chem 56: 3689-700 (2013) Article DOI: 10.1021/jm4002296 BindingDB Entry DOI: 10.7270/Q25M673W
					More data for this Ligand-Target Pair				3D Structure (crystal)
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50536439 (CHEMBL4581001) Show SMILES C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](C[C@H]1CC[C@@H](CC1)C1CCCCC1)NC(=O)[C@H](Cc1ccccc1)N=[N+]=[N-])C(=O)[C@@]1(C)CO1 |r,wU:16.32,1.0,33.44,18.18,wD:5.5,46.50,21.25,(72.07,-6.39,;72.07,-7.72,;70.74,-8.5,;69.41,-7.72,;69.41,-6.18,;68.07,-8.5,;68.07,-10.04,;69.41,-10.82,;69.4,-12.36,;70.73,-13.13,;72.07,-12.36,;72.06,-10.81,;70.73,-10.04,;66.73,-7.72,;65.4,-8.5,;65.4,-10.04,;64.06,-7.73,;64.06,-6.18,;65.39,-5.41,;65.38,-3.87,;66.72,-3.11,;68.04,-3.88,;68.04,-5.42,;66.71,-6.18,;69.37,-3.12,;70.7,-3.9,;72.03,-3.14,;72.04,-1.6,;70.7,-.83,;69.37,-1.59,;62.72,-8.5,;61.39,-7.72,;61.39,-6.18,;60.06,-8.5,;58.72,-7.72,;57.38,-8.5,;56.05,-7.73,;54.72,-8.5,;54.71,-10.04,;56.06,-10.82,;57.38,-10.04,;60.06,-10.04,;61.33,-10.9,;62.62,-11.75,;73.41,-8.5,;73.41,-10.04,;74.75,-7.71,;75.84,-8.81,;74.74,-6.17,;76.08,-6.94,)| Show InChI InChI=1S/C39H52N6O5/c1-26(35(46)39(2)25-50-39)41-36(47)32(22-27-12-6-3-7-13-27)42-37(48)33(23-29-18-20-31(21-19-29)30-16-10-5-11-17-30)43-38(49)34(44-45-40)24-28-14-8-4-9-15-28/h3-4,6-9,12-15,26,29-34H,5,10-11,16-25H2,1-2H3,(H,41,47)(H,42,48)(H,43,49)/t26-,29-,31-,32-,33-,34-,39+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.90	n/a	n/a	n/a	n/a	n/a	n/a
Leiden Institute of Chemistry Curated by ChEMBL					Assay Description Inhibition of catalytic activity of constitutive proteasome 20s subunit beta5 in human Raji cells incubated for 1 hr by BODIPY(TMR)-NC-005-VS probe b...				J Med Chem 59: 7177-87 (2016) Article DOI: 10.1021/acs.jmedchem.6b00705 BindingDB Entry DOI: 10.7270/Q2Z60SJ2
					More data for this Ligand-Target Pair
Proteasome subunit beta type-2 (Homo sapiens (Human))	BDBM50517643 (CHEMBL4451682) Show SMILES CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)N=[N+]=[N-])C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1ccc(CN)cc1)\C=C\S(C)(=O)=O |r| Show InChI InChI=1S/C30H41N7O5S/c1-20(2)16-26(35-30(40)27(36-37-32)18-22-8-6-5-7-9-22)29(39)33-21(3)28(38)34-25(14-15-43(4,41)42)17-23-10-12-24(19-31)13-11-23/h5-15,20-21,25-27H,16-19,31H2,1-4H3,(H,33,39)(H,34,38)(H,35,40)/b15-14+/t21-,25+,26-,27-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Leiden Institute of Chemistry and Netherlands Proteomics Centre Curated by ChEMBL					Assay Description Inhibition of 20S constitutive proteasome beta 2 trypsin-like activity in human Raji cell lysates after 1 hr by competitive ABPP assay				J Med Chem 62: 1626-1642 (2019) Article DOI: 10.1021/acs.jmedchem.8b01884 BindingDB Entry DOI: 10.7270/Q28P63XM
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50470555 (CHEMBL4293394) Show SMILES [H][C@]1([C@@H](C)CC)[C@@H](OC1=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)OCc1ccccc1 |r| Show InChI InChI=1S/C26H38N2O6/c1-7-17(6)20-22(34-25(20)31)24(30)27-19(13-15(2)3)23(29)28-21(16(4)5)26(32)33-14-18-11-9-8-10-12-18/h8-12,15-17,19-22H,7,13-14H2,1-6H3,(H,27,30)(H,28,29)/t17-,19-,20-,21-,22+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
New Mexico Institute of Mining and Technology Curated by ChEMBL					Assay Description Inhibition of 20S proteasome beta5 subunit in human Jurkat cell lysate using Suc-LLVY-AMC as substrate pretreated for 30 mins followed by substrate a...				Eur J Med Chem 157: 962-977 (2018) Article DOI: 10.1016/j.ejmech.2018.08.052 BindingDB Entry DOI: 10.7270/Q2028V7T
					More data for this Ligand-Target Pair
Proteasome subunit beta type-8 (Homo sapiens (Human))	BDBM50099683 (CHEMBL3319484) Show SMILES C[C@@H](NC(=O)C1=C(C)c2ccccc2C1)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](Cc1ccc(cc1)-c1ccccc1)C(=O)[C@@]1(C)CO1 |r,c:5| Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Leiden Institute of Chemistry and Netherlands Proteomics Centre Curated by ChEMBL					Assay Description Inhibition of proteasome subunit beta-5i in human Raji cells using BODIPY-NC005 by fluorescent densitometry				J Med Chem 57: 6197-209 (2014) Article DOI: 10.1021/jm500716s BindingDB Entry DOI: 10.7270/Q2BR8TZT
					More data for this Ligand-Target Pair
Proteasome subunit beta type-8 (Homo sapiens (Human))	BDBM50099687 (CHEMBL3319580) Show SMILES COc1ccc(C[C@H](NC(=O)[C@H](C)NC(=O)C2=C(C)c3ccccc3C2)C(=O)N[C@@H](Cc2ccccc2)C(=O)[C@@]2(C)CO2)cc1 |r,c:16| Show InChI InChI=1S/C36H39N3O6/c1-22-28-13-9-8-12-26(28)20-29(22)34(42)37-23(2)33(41)39-31(19-25-14-16-27(44-4)17-15-25)35(43)38-30(32(40)36(3)21-45-36)18-24-10-6-5-7-11-24/h5-17,23,30-31H,18-21H2,1-4H3,(H,37,42)(H,38,43)(H,39,41)/t23-,30-,31-,36+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Leiden Institute of Chemistry and Netherlands Proteomics Centre Curated by ChEMBL					Assay Description Inhibition of proteasome subunit beta-5i in human Raji cells using BODIPY-NC005 by fluorescent densitometry				J Med Chem 57: 6197-209 (2014) Article DOI: 10.1021/jm500716s BindingDB Entry DOI: 10.7270/Q2BR8TZT
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50536431 (CHEMBL4519899) Show SMILES CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCc1ccccc1)NC(=O)[C@H](Cc1ccccc1)N=[N+]=[N-])C(=O)[C@@]1(C)CO1 |r| Show InChI InChI=1S/C37H44N6O5/c1-25(2)21-30(33(44)37(3)24-48-37)40-35(46)31(22-27-15-9-5-10-16-27)41-34(45)29(20-19-26-13-7-4-8-14-26)39-36(47)32(42-43-38)23-28-17-11-6-12-18-28/h4-18,25,29-32H,19-24H2,1-3H3,(H,39,47)(H,40,46)(H,41,45)/t29-,30-,31-,32-,37+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.10	n/a	n/a	n/a	n/a	n/a	n/a
Leiden Institute of Chemistry Curated by ChEMBL					Assay Description Inhibition of catalytic activity of immunoproteasome 20s subunit beta5 in human Raji cells incubated for 1 hr by BODIPY(TMR)-NC-005-VS probe based co...				J Med Chem 59: 7177-87 (2016) Article DOI: 10.1021/acs.jmedchem.6b00705 BindingDB Entry DOI: 10.7270/Q2Z60SJ2
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50536431 (CHEMBL4519899) Show SMILES CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCc1ccccc1)NC(=O)[C@H](Cc1ccccc1)N=[N+]=[N-])C(=O)[C@@]1(C)CO1 |r| Show InChI InChI=1S/C37H44N6O5/c1-25(2)21-30(33(44)37(3)24-48-37)40-35(46)31(22-27-15-9-5-10-16-27)41-34(45)29(20-19-26-13-7-4-8-14-26)39-36(47)32(42-43-38)23-28-17-11-6-12-18-28/h4-18,25,29-32H,19-24H2,1-3H3,(H,39,47)(H,40,46)(H,41,45)/t29-,30-,31-,32-,37+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.10	n/a	n/a	n/a	n/a	n/a	n/a
Leiden Institute of Chemistry Curated by ChEMBL					Assay Description Inhibition of catalytic activity of immunoproteasome 20s subunit beta5 in human Raji cells incubated for 1 hr by BODIPY(TMR)-NC-005-VS probe based co...				J Med Chem 59: 7177-87 (2016) Article DOI: 10.1021/acs.jmedchem.6b00705 BindingDB Entry DOI: 10.7270/Q2Z60SJ2
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50430967 (CHEMBL2337848) Show SMILES CC[C@H](C)C(=O)C(=O)N[C@H]1Cc2ccc(O)c(c2)-c2cccc3c2NC(=O)[C@@]3(O)[C@H](O)[C@H](NC(=O)[C@H](CC(N)=O)CC1=O)C(=O)N\C=C/C |r| Show InChI InChI=1S/C34H39N5O10/c1-4-11-36-31(46)27-29(44)34(49)21-8-6-7-19(26(21)39-33(34)48)20-12-17(9-10-23(20)40)13-22(37-32(47)28(43)16(3)5-2)24(41)14-18(15-25(35)42)30(45)38-27/h4,6-12,16,18,22,27,29,40,44,49H,5,13-15H2,1-3H3,(H2,35,42)(H,36,46)(H,37,47)(H,38,45)(H,39,48)/b11-4-/t16-,18-,22-,27-,29+,34-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.40	n/a	n/a	n/a	n/a	n/a	n/a
University Paris 6 Curated by ChEMBL					Assay Description Inhibition of chymotrypsin-like activity of human constitutive 20s proteasome beta-5 subunit using Suc-LLVY-AMC as substrate assessed as remaining ac...				J Med Chem 56: 3367-78 (2013) Article DOI: 10.1021/jm4002007 BindingDB Entry DOI: 10.7270/Q2F19135
					More data for this Ligand-Target Pair
Proteasome subunit beta type-5 (Homo sapiens (Human))	BDBM50307481 ((S)-2-azido-N-((S)-1-((S)-1-((S)-4-methyl-1-((R)-2...) Show SMILES CC(C)C[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccccc1)N=[N+]=[N-])C(=O)[C@@]1(C)CO1 |r| Show InChI InChI=1S/C36H42N6O5/c1-24(2)19-28(32(43)36(3)23-47-36)38-33(44)29(20-25-13-7-4-8-14-25)39-34(45)30(21-26-15-9-5-10-16-26)40-35(46)31(41-42-37)22-27-17-11-6-12-18-27/h4-18,24,28-31H,19-23H2,1-3H3,(H,38,44)(H,39,45)(H,40,46)/t28-,29-,30-,31-,36+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.5	n/a	n/a	n/a	n/a	n/a	n/a
Leiden Institute of Chemistry Curated by ChEMBL					Assay Description Inhibition of catalytic activity of immunoproteasome 20s subunit beta5 in human Raji cells incubated for 1 hr by BODIPY(TMR)-NC-005-VS probe based co...				J Med Chem 59: 7177-87 (2016) Article DOI: 10.1021/acs.jmedchem.6b00705 BindingDB Entry DOI: 10.7270/Q2Z60SJ2
					More data for this Ligand-Target Pair

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