Found 134 hits with Last Name = 'aulner' and Initial = 'n' Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Transcription factor p65
(Homo sapiens (Human)) | BDBM50372501
![PNG](/data/jpeg/tenK5037/BindingDB_50372501.png) (CHEMBL271669)Show InChI InChI=1S/C16H12N2O2S/c1-10-4-7-14-13(9-10)12-6-5-11-3-2-8-17-15(11)16(12)18-21(14,19)20/h2-9,18H,1H3 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 600 | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University
Curated by ChEMBL
| Assay Description Inhibition of TNF-alpha-stimulated human NF-kappaB p65 RelA subunit nuclear translocation in HUVEC |
Bioorg Med Chem Lett 18: 329-35 (2008)
Article DOI: 10.1016/j.bmcl.2007.10.100 BindingDB Entry DOI: 10.7270/Q2348M63 |
More data for this Ligand-Target Pair | |
Huntingtin
(Homo sapiens (Human)) | BDBM50257650
![PNG](/data/jpeg/tenK5025/BindingDB_50257650.png) (4-(2-(6-chloroquinazolin-4-ylamino)ethyl)phenol | ...)Show InChI InChI=1S/C16H14ClN3O/c17-12-3-6-15-14(9-12)16(20-10-19-15)18-8-7-11-1-4-13(21)5-2-11/h1-6,9-10,21H,7-8H2,(H,18,19,20) | PDB
KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 710 | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University
Curated by ChEMBL
| Assay Description Inhibition of Huntingtin protein aggregation by cell based assay |
Bioorg Med Chem Lett 19: 1715-7 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.087 BindingDB Entry DOI: 10.7270/Q2Q2403P |
More data for this Ligand-Target Pair | |
Transcription factor p65
(Homo sapiens (Human)) | BDBM50372523
![PNG](/data/jpeg/tenK5037/BindingDB_50372523.png) (CHEMBL402638)Show SMILES Cc1ccc2cccc(NS(=O)(=O)c3cccc(c3)[N+]([O-])=O)c2n1 Show InChI InChI=1S/C16H13N3O4S/c1-11-8-9-12-4-2-7-15(16(12)17-11)18-24(22,23)14-6-3-5-13(10-14)19(20)21/h2-10,18H,1H3 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 900 | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University
Curated by ChEMBL
| Assay Description Inhibition of TNF-alpha-stimulated human NF-kappaB p65 RelA subunit nuclear translocation in HUVEC |
Bioorg Med Chem Lett 18: 329-35 (2008)
Article DOI: 10.1016/j.bmcl.2007.10.100 BindingDB Entry DOI: 10.7270/Q2348M63 |
More data for this Ligand-Target Pair | |
Transcription factor p65
(Homo sapiens (Human)) | BDBM50372496
![PNG](/data/jpeg/tenK5037/BindingDB_50372496.png) (CHEMBL273149)Show SMILES COc1cc2ccc(C)nc2c2NS(=O)(=O)c3ccc(C)cc3-c12 Show InChI InChI=1S/C18H16N2O3S/c1-10-4-7-15-13(8-10)16-14(23-3)9-12-6-5-11(2)19-17(12)18(16)20-24(15,21)22/h4-9,20H,1-3H3 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 900 | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University
Curated by ChEMBL
| Assay Description Inhibition of TNF-alpha-stimulated human NF-kappaB p65 RelA subunit nuclear translocation in HUVEC |
Bioorg Med Chem Lett 18: 329-35 (2008)
Article DOI: 10.1016/j.bmcl.2007.10.100 BindingDB Entry DOI: 10.7270/Q2348M63 |
More data for this Ligand-Target Pair | |
Transcription factor p65
(Homo sapiens (Human)) | BDBM50372506
![PNG](/data/jpeg/tenK5037/BindingDB_50372506.png) (CHEMBL256061)Show InChI InChI=1S/C17H17N3O3S/c1-11-5-6-16(14(18)8-11)24(21,22)20-15-10-13(23-2)9-12-4-3-7-19-17(12)15/h3-10,20H,18H2,1-2H3 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University
Curated by ChEMBL
| Assay Description Inhibition of TNF-alpha-stimulated human NF-kappaB p65 RelA subunit nuclear translocation in HUVEC |
Bioorg Med Chem Lett 18: 329-35 (2008)
Article DOI: 10.1016/j.bmcl.2007.10.100 BindingDB Entry DOI: 10.7270/Q2348M63 |
More data for this Ligand-Target Pair | |
Transcription factor p65
(Homo sapiens (Human)) | BDBM50372493
![PNG](/data/jpeg/tenK5037/BindingDB_50372493.png) (CHEMBL404128)Show InChI InChI=1S/C16H12N2O3S/c1-21-11-5-7-14-13(9-11)12-6-4-10-3-2-8-17-15(10)16(12)18-22(14,19)20/h2-9,18H,1H3 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University
Curated by ChEMBL
| Assay Description Inhibition of TNF-alpha-stimulated human NF-kappaB p65 RelA subunit nuclear translocation in HUVEC |
Bioorg Med Chem Lett 18: 329-35 (2008)
Article DOI: 10.1016/j.bmcl.2007.10.100 BindingDB Entry DOI: 10.7270/Q2348M63 |
More data for this Ligand-Target Pair | |
Transcription factor p65
(Homo sapiens (Human)) | BDBM36894
![PNG](/data/jpeg/tenK3/BindingDB_36894.png) (5H-quinolino[8,7-c][1,2]benzothiazine 6,6-dioxide ...)Show InChI InChI=1S/C15H10N2O2S/c18-20(19)13-6-2-1-5-11(13)12-8-7-10-4-3-9-16-14(10)15(12)17-20/h1-9,17H | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| Purchase
PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University
Curated by ChEMBL
| Assay Description Inhibition of TNF-alpha-stimulated human NF-kappaB p65 RelA subunit nuclear translocation in HUVEC |
Bioorg Med Chem Lett 18: 329-35 (2008)
Article DOI: 10.1016/j.bmcl.2007.10.100 BindingDB Entry DOI: 10.7270/Q2348M63 |
More data for this Ligand-Target Pair | |
Transcription factor p65
(Homo sapiens (Human)) | BDBM50372502
![PNG](/data/jpeg/tenK5037/BindingDB_50372502.png) (CHEMBL256403)Show InChI InChI=1S/C14H11ClN2O2S2/c1-9-5-6-10-3-2-4-11(14(10)16-9)17-21(18,19)13-8-7-12(15)20-13/h2-8,17H,1H3 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University
Curated by ChEMBL
| Assay Description Inhibition of TNF-alpha-stimulated human NF-kappaB p65 RelA subunit nuclear translocation in HUVEC |
Bioorg Med Chem Lett 18: 329-35 (2008)
Article DOI: 10.1016/j.bmcl.2007.10.100 BindingDB Entry DOI: 10.7270/Q2348M63 |
More data for this Ligand-Target Pair | |
Transcription factor p65
(Homo sapiens (Human)) | BDBM50372516
![PNG](/data/jpeg/tenK5037/BindingDB_50372516.png) (CHEMBL272552)Show SMILES FC(F)(F)c1ccc2c(c1)-c1ccc3cccnc3c1NS2(=O)=O Show InChI InChI=1S/C16H9F3N2O2S/c17-16(18,19)10-4-6-13-12(8-10)11-5-3-9-2-1-7-20-14(9)15(11)21-24(13,22)23/h1-8,21H | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University
Curated by ChEMBL
| Assay Description Inhibition of TNF-alpha-stimulated human NF-kappaB p65 RelA subunit nuclear translocation in HUVEC |
Bioorg Med Chem Lett 18: 329-35 (2008)
Article DOI: 10.1016/j.bmcl.2007.10.100 BindingDB Entry DOI: 10.7270/Q2348M63 |
More data for this Ligand-Target Pair | |
Transcription factor p65
(Homo sapiens (Human)) | BDBM50372520
![PNG](/data/jpeg/tenK5037/BindingDB_50372520.png) (CHEMBL271233)Show SMILES COc1ccc(c(c1)[N+]([O-])=O)S(=O)(=O)Nc1cccc2ccc(C)nc12 Show InChI InChI=1S/C17H15N3O5S/c1-11-6-7-12-4-3-5-14(17(12)18-11)19-26(23,24)16-9-8-13(25-2)10-15(16)20(21)22/h3-10,19H,1-2H3 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University
Curated by ChEMBL
| Assay Description Inhibition of TNF-alpha-stimulated human NF-kappaB p65 RelA subunit nuclear translocation in HUVEC |
Bioorg Med Chem Lett 18: 329-35 (2008)
Article DOI: 10.1016/j.bmcl.2007.10.100 BindingDB Entry DOI: 10.7270/Q2348M63 |
More data for this Ligand-Target Pair | |
Huntingtin
(Homo sapiens (Human)) | BDBM50257498
![PNG](/data/jpeg/tenK5025/BindingDB_50257498.png) (4-(4-(benzo[d][1,3]dioxol-5-ylmethyl)piperazin-1-y...)Show InChI InChI=1S/C20H19ClN4O2/c21-15-2-3-17-16(10-15)20(23-12-22-17)25-7-5-24(6-8-25)11-14-1-4-18-19(9-14)27-13-26-18/h1-4,9-10,12H,5-8,11,13H2 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.07E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University
Curated by ChEMBL
| Assay Description Inhibition of Huntingtin protein aggregation by cell based assay |
Bioorg Med Chem Lett 19: 1715-7 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.087 BindingDB Entry DOI: 10.7270/Q2Q2403P |
More data for this Ligand-Target Pair | |
Transcription factor p65
(Homo sapiens (Human)) | BDBM50372503
![PNG](/data/jpeg/tenK5037/BindingDB_50372503.png) (CHEMBL401504)Show InChI InChI=1S/C13H9BrN2O2S2/c14-11-6-7-12(19-11)20(17,18)16-10-5-1-3-9-4-2-8-15-13(9)10/h1-8,16H | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| Purchase
CHEMBL MCE PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University
Curated by ChEMBL
| Assay Description Inhibition of TNF-alpha-stimulated human NF-kappaB p65 RelA subunit nuclear translocation in HUVEC |
Bioorg Med Chem Lett 18: 329-35 (2008)
Article DOI: 10.1016/j.bmcl.2007.10.100 BindingDB Entry DOI: 10.7270/Q2348M63 |
More data for this Ligand-Target Pair | |
Transcription factor p65
(Homo sapiens (Human)) | BDBM50372522
![PNG](/data/jpeg/tenK5037/BindingDB_50372522.png) (CHEMBL269941)Show SMILES Cc1ccc2cccc(NS(=O)(=O)c3ccc(cc3[N+]([O-])=O)C(F)(F)F)c2n1 Show InChI InChI=1S/C17H12F3N3O4S/c1-10-5-6-11-3-2-4-13(16(11)21-10)22-28(26,27)15-8-7-12(17(18,19)20)9-14(15)23(24)25/h2-9,22H,1H3 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University
Curated by ChEMBL
| Assay Description Inhibition of TNF-alpha-stimulated human NF-kappaB p65 RelA subunit nuclear translocation in HUVEC |
Bioorg Med Chem Lett 18: 329-35 (2008)
Article DOI: 10.1016/j.bmcl.2007.10.100 BindingDB Entry DOI: 10.7270/Q2348M63 |
More data for this Ligand-Target Pair | |
Transcription factor p65
(Homo sapiens (Human)) | BDBM50372498
![PNG](/data/jpeg/tenK5037/BindingDB_50372498.png) (CHEMBL429599)Show InChI InChI=1S/C15H9ClN2O2S/c16-10-4-6-13-12(8-10)11-5-3-9-2-1-7-17-14(9)15(11)18-21(13,19)20/h1-8,18H | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University
Curated by ChEMBL
| Assay Description Inhibition of TNF-alpha-stimulated human NF-kappaB p65 RelA subunit nuclear translocation in HUVEC |
Bioorg Med Chem Lett 18: 329-35 (2008)
Article DOI: 10.1016/j.bmcl.2007.10.100 BindingDB Entry DOI: 10.7270/Q2348M63 |
More data for this Ligand-Target Pair | |
Huntingtin
(Homo sapiens (Human)) | BDBM50257649
![PNG](/data/jpeg/tenK5025/BindingDB_50257649.png) (4-(2-(6-bromoquinazolin-4-ylamino)ethyl)phenol | C...)Show InChI InChI=1S/C16H14BrN3O/c17-12-3-6-15-14(9-12)16(20-10-19-15)18-8-7-11-1-4-13(21)5-2-11/h1-6,9-10,21H,7-8H2,(H,18,19,20) | PDB
KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.11E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University
Curated by ChEMBL
| Assay Description Inhibition of Huntingtin protein aggregation by cell based assay |
Bioorg Med Chem Lett 19: 1715-7 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.087 BindingDB Entry DOI: 10.7270/Q2Q2403P |
More data for this Ligand-Target Pair | |
Transcription factor p65
(Homo sapiens (Human)) | BDBM50372494
![PNG](/data/jpeg/tenK5037/BindingDB_50372494.png) (CHEMBL273148)Show SMILES Cc1ccc2ccc-3c(NS(=O)(=O)c4ccc(cc-34)C(F)(F)F)c2n1 Show InChI InChI=1S/C17H11F3N2O2S/c1-9-2-3-10-4-6-12-13-8-11(17(18,19)20)5-7-14(13)25(23,24)22-16(12)15(10)21-9/h2-8,22H,1H3 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University
Curated by ChEMBL
| Assay Description Inhibition of TNF-alpha-stimulated human NF-kappaB p65 RelA subunit nuclear translocation in HUVEC |
Bioorg Med Chem Lett 18: 329-35 (2008)
Article DOI: 10.1016/j.bmcl.2007.10.100 BindingDB Entry DOI: 10.7270/Q2348M63 |
More data for this Ligand-Target Pair | |
Transcription factor p65
(Homo sapiens (Human)) | BDBM50372500
![PNG](/data/jpeg/tenK5037/BindingDB_50372500.png) (CHEMBL272553)Show InChI InChI=1S/C17H14N2O3S/c1-10-5-6-14-12(8-10)15-13(22-2)9-11-4-3-7-18-16(11)17(15)19-23(14,20)21/h3-9,19H,1-2H3 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University
Curated by ChEMBL
| Assay Description Inhibition of TNF-alpha-stimulated human NF-kappaB p65 RelA subunit nuclear translocation in HUVEC |
Bioorg Med Chem Lett 18: 329-35 (2008)
Article DOI: 10.1016/j.bmcl.2007.10.100 BindingDB Entry DOI: 10.7270/Q2348M63 |
More data for this Ligand-Target Pair | |
Transcription factor p65
(Homo sapiens (Human)) | BDBM50372504
![PNG](/data/jpeg/tenK5037/BindingDB_50372504.png) (CHEMBL257446)Show InChI InChI=1S/C13H9ClN2O2S2/c14-11-6-7-12(19-11)20(17,18)16-10-5-1-3-9-4-2-8-15-13(9)10/h1-8,16H | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
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CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University
Curated by ChEMBL
| Assay Description Inhibition of TNF-alpha-stimulated human NF-kappaB p65 RelA subunit nuclear translocation in HUVEC |
Bioorg Med Chem Lett 18: 329-35 (2008)
Article DOI: 10.1016/j.bmcl.2007.10.100 BindingDB Entry DOI: 10.7270/Q2348M63 |
More data for this Ligand-Target Pair | |
Huntingtin
(Homo sapiens (Human)) | BDBM50258237
![PNG](/data/jpeg/tenK5025/BindingDB_50258237.png) (6-bromo-4-(4-methylpiperazin-1-yl)quinazoline | CH...)Show InChI InChI=1S/C13H15BrN4/c1-17-4-6-18(7-5-17)13-11-8-10(14)2-3-12(11)15-9-16-13/h2-3,8-9H,4-7H2,1H3 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
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CHEMBL MCE PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.31E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University
Curated by ChEMBL
| Assay Description Inhibition of Huntingtin protein aggregation by cell based assay |
Bioorg Med Chem Lett 19: 1715-7 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.087 BindingDB Entry DOI: 10.7270/Q2Q2403P |
More data for this Ligand-Target Pair | |
Transcription factor p65
(Homo sapiens (Human)) | BDBM50372517
![PNG](/data/jpeg/tenK5037/BindingDB_50372517.png) (CHEMBL256609)Show InChI InChI=1S/C14H11BrN2O2S2/c1-9-5-6-10-3-2-4-11(14(10)16-9)17-21(18,19)13-8-7-12(15)20-13/h2-8,17H,1H3 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University
Curated by ChEMBL
| Assay Description Inhibition of TNF-alpha-stimulated human NF-kappaB p65 RelA subunit nuclear translocation in HUVEC |
Bioorg Med Chem Lett 18: 329-35 (2008)
Article DOI: 10.1016/j.bmcl.2007.10.100 BindingDB Entry DOI: 10.7270/Q2348M63 |
More data for this Ligand-Target Pair | |
Transcription factor p65
(Homo sapiens (Human)) | BDBM50372514
![PNG](/data/jpeg/tenK5037/BindingDB_50372514.png) (CHEMBL540966)Show SMILES [O-][N+](=O)c1ccc(cc1)S(=O)(=O)Nc1cccc2cccnc12 Show InChI InChI=1S/C15H11N3O4S/c19-18(20)12-6-8-13(9-7-12)23(21,22)17-14-5-1-3-11-4-2-10-16-15(11)14/h1-10,17H | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
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CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University
Curated by ChEMBL
| Assay Description Inhibition of TNF-alpha-stimulated human NF-kappaB p65 RelA subunit nuclear translocation in HUVEC |
Bioorg Med Chem Lett 18: 329-35 (2008)
Article DOI: 10.1016/j.bmcl.2007.10.100 BindingDB Entry DOI: 10.7270/Q2348M63 |
More data for this Ligand-Target Pair | |
Transcription factor p65
(Homo sapiens (Human)) | BDBM50372512
![PNG](/data/jpeg/tenK5037/BindingDB_50372512.png) (CHEMBL429586)Show SMILES Cc1ccc(cc1S(=O)(=O)Nc1cccc2cccnc12)[N+]([O-])=O Show InChI InChI=1S/C16H13N3O4S/c1-11-7-8-13(19(20)21)10-15(11)24(22,23)18-14-6-2-4-12-5-3-9-17-16(12)14/h2-10,18H,1H3 | PDB
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CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University
Curated by ChEMBL
| Assay Description Inhibition of TNF-alpha-stimulated human NF-kappaB p65 RelA subunit nuclear translocation in HUVEC |
Bioorg Med Chem Lett 18: 329-35 (2008)
Article DOI: 10.1016/j.bmcl.2007.10.100 BindingDB Entry DOI: 10.7270/Q2348M63 |
More data for this Ligand-Target Pair | |
Transcription factor p65
(Homo sapiens (Human)) | BDBM50372499
![PNG](/data/jpeg/tenK5037/BindingDB_50372499.png) (CHEMBL270799)Show InChI InChI=1S/C15H9FN2O2S/c16-10-4-6-13-12(8-10)11-5-3-9-2-1-7-17-14(9)15(11)18-21(13,19)20/h1-8,18H | PDB
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| Article PubMed
| n/a | n/a | 1.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University
Curated by ChEMBL
| Assay Description Inhibition of TNF-alpha-stimulated human NF-kappaB p65 RelA subunit nuclear translocation in HUVEC |
Bioorg Med Chem Lett 18: 329-35 (2008)
Article DOI: 10.1016/j.bmcl.2007.10.100 BindingDB Entry DOI: 10.7270/Q2348M63 |
More data for this Ligand-Target Pair | |
Transcription factor p65
(Homo sapiens (Human)) | BDBM50372507
![PNG](/data/jpeg/tenK5037/BindingDB_50372507.png) (CHEMBL256062)Show InChI InChI=1S/C15H13N3O2S/c16-12-7-1-2-9-14(12)21(19,20)18-13-8-3-5-11-6-4-10-17-15(11)13/h1-10,18H,16H2 | PDB
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Similars
| Article PubMed
| n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University
Curated by ChEMBL
| Assay Description Inhibition of TNF-alpha-stimulated human NF-kappaB p65 RelA subunit nuclear translocation in HUVEC |
Bioorg Med Chem Lett 18: 329-35 (2008)
Article DOI: 10.1016/j.bmcl.2007.10.100 BindingDB Entry DOI: 10.7270/Q2348M63 |
More data for this Ligand-Target Pair | |
Transcription factor p65
(Homo sapiens (Human)) | BDBM53740
![PNG](/data/jpeg/tenK5/BindingDB_53740.png) (2-[(5-chloro-4-tosyl-thiazol-2-yl)amino]ethyl-dime...)Show InChI InChI=1S/C14H18ClN3O2S2/c1-10-4-6-11(7-5-10)22(19,20)13-12(15)21-14(17-13)16-8-9-18(2)3/h4-7H,8-9H2,1-3H3,(H,16,17) | PDB
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Similars
| Article PubMed
| n/a | n/a | 2.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University
Curated by ChEMBL
| Assay Description Inhibition of TNF-alpha-stimulated human NF-kappaB p65 RelA subunit nuclear translocation in HUVEC |
Bioorg Med Chem Lett 18: 329-35 (2008)
Article DOI: 10.1016/j.bmcl.2007.10.100 BindingDB Entry DOI: 10.7270/Q2348M63 |
More data for this Ligand-Target Pair | |
Transcription factor p65
(Homo sapiens (Human)) | BDBM50372510
![PNG](/data/jpeg/tenK5037/BindingDB_50372510.png) (CHEMBL269942)Show SMILES COc1cc(NS(=O)(=O)c2ccc(C)cc2[N+]([O-])=O)c2ncccc2c1 Show InChI InChI=1S/C17H15N3O5S/c1-11-5-6-16(15(8-11)20(21)22)26(23,24)19-14-10-13(25-2)9-12-4-3-7-18-17(12)14/h3-10,19H,1-2H3 | PDB
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| Article PubMed
| n/a | n/a | 2.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University
Curated by ChEMBL
| Assay Description Inhibition of TNF-alpha-stimulated human NF-kappaB p65 RelA subunit nuclear translocation in HUVEC |
Bioorg Med Chem Lett 18: 329-35 (2008)
Article DOI: 10.1016/j.bmcl.2007.10.100 BindingDB Entry DOI: 10.7270/Q2348M63 |
More data for this Ligand-Target Pair | |
Huntingtin
(Homo sapiens (Human)) | BDBM50258233
![PNG](/data/jpeg/tenK5025/BindingDB_50258233.png) (6-bromo-4-(4-ethylpiperazin-1-yl)quinazoline | CHE...)Show InChI InChI=1S/C14H17BrN4/c1-2-18-5-7-19(8-6-18)14-12-9-11(15)3-4-13(12)16-10-17-14/h3-4,9-10H,2,5-8H2,1H3 | PDB
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| Article PubMed
| n/a | n/a | 2.21E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University
Curated by ChEMBL
| Assay Description Inhibition of Huntingtin protein aggregation by cell based assay |
Bioorg Med Chem Lett 19: 1715-7 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.087 BindingDB Entry DOI: 10.7270/Q2Q2403P |
More data for this Ligand-Target Pair | |
Transcription factor p65
(Homo sapiens (Human)) | BDBM50372495
![PNG](/data/jpeg/tenK5037/BindingDB_50372495.png) (CHEMBL273147)Show InChI InChI=1S/C17H14N2O3S/c1-10-3-4-11-5-7-13-14-9-12(22-2)6-8-15(14)23(20,21)19-17(13)16(11)18-10/h3-9,19H,1-2H3 | PDB
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| Article PubMed
| n/a | n/a | 2.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University
Curated by ChEMBL
| Assay Description Inhibition of TNF-alpha-stimulated human NF-kappaB p65 RelA subunit nuclear translocation in HUVEC |
Bioorg Med Chem Lett 18: 329-35 (2008)
Article DOI: 10.1016/j.bmcl.2007.10.100 BindingDB Entry DOI: 10.7270/Q2348M63 |
More data for this Ligand-Target Pair | |
Transcription factor p65
(Homo sapiens (Human)) | BDBM50372525
![PNG](/data/jpeg/tenK5037/BindingDB_50372525.png) (CHEMBL270584)Show InChI InChI=1S/C16H12N2O3S/c1-21-11-8-10-6-7-13-12-4-2-3-5-14(12)22(19,20)18-16(13)15(10)17-9-11/h2-9,18H,1H3 | PDB
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| Article PubMed
| n/a | n/a | 2.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University
Curated by ChEMBL
| Assay Description Inhibition of TNF-alpha-stimulated human NF-kappaB p65 RelA subunit nuclear translocation in HUVEC |
Bioorg Med Chem Lett 18: 329-35 (2008)
Article DOI: 10.1016/j.bmcl.2007.10.100 BindingDB Entry DOI: 10.7270/Q2348M63 |
More data for this Ligand-Target Pair | |
Huntingtin
(Homo sapiens (Human)) | BDBM50257497
![PNG](/data/jpeg/tenK5025/BindingDB_50257497.png) (6-bromo-4-(piperazin-1-yl)quinazoline | CHEMBL5099...)Show InChI InChI=1S/C12H13BrN4/c13-9-1-2-11-10(7-9)12(16-8-15-11)17-5-3-14-4-6-17/h1-2,7-8,14H,3-6H2 | PDB
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| Article PubMed
| n/a | n/a | 2.74E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University
Curated by ChEMBL
| Assay Description Inhibition of Huntingtin protein aggregation by cell based assay |
Bioorg Med Chem Lett 19: 1715-7 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.087 BindingDB Entry DOI: 10.7270/Q2Q2403P |
More data for this Ligand-Target Pair | |
Transcription factor p65
(Homo sapiens (Human)) | BDBM50372519
![PNG](/data/jpeg/tenK5037/BindingDB_50372519.png) (CHEMBL258314)Show InChI InChI=1S/C16H15N3O2S/c1-11-9-10-12-5-4-7-14(16(12)18-11)19-22(20,21)15-8-3-2-6-13(15)17/h2-10,19H,17H2,1H3 | PDB
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| Article PubMed
| n/a | n/a | 2.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University
Curated by ChEMBL
| Assay Description Inhibition of TNF-alpha-stimulated human NF-kappaB p65 RelA subunit nuclear translocation in HUVEC |
Bioorg Med Chem Lett 18: 329-35 (2008)
Article DOI: 10.1016/j.bmcl.2007.10.100 BindingDB Entry DOI: 10.7270/Q2348M63 |
More data for this Ligand-Target Pair | |
Transcription factor p65
(Homo sapiens (Human)) | BDBM50372524
![PNG](/data/jpeg/tenK5037/BindingDB_50372524.png) (BAY-11-7082 | CHEMBL403183)Show InChI InChI=1S/C10H9NO2S/c1-9-3-5-10(6-4-9)14(12,13)8-2-7-11/h2-6,8H,1H3/b8-2+ | PDB
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| Article PubMed
| n/a | n/a | 3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University
Curated by ChEMBL
| Assay Description Inhibition of TNF-alpha-stimulated human NF-kappaB p65 RelA subunit nuclear translocation in HUVEC |
Bioorg Med Chem Lett 18: 329-35 (2008)
Article DOI: 10.1016/j.bmcl.2007.10.100 BindingDB Entry DOI: 10.7270/Q2348M63 |
More data for this Ligand-Target Pair | |
Transcription factor p65
(Homo sapiens (Human)) | BDBM60287
![PNG](/data/jpeg/tenK6/BindingDB_60287.png) (2-nitro-N-(8-quinolinyl)benzenesulfonamide | 2-nit...)Show SMILES [O-][N+](=O)c1ccccc1S(=O)(=O)Nc1cccc2cccnc12 Show InChI InChI=1S/C15H11N3O4S/c19-18(20)13-8-1-2-9-14(13)23(21,22)17-12-7-3-5-11-6-4-10-16-15(11)12/h1-10,17H | PDB
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| Article PubMed
| n/a | n/a | 3.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University
Curated by ChEMBL
| Assay Description Inhibition of TNF-alpha-stimulated human NF-kappaB p65 RelA subunit nuclear translocation in HUVEC |
Bioorg Med Chem Lett 18: 329-35 (2008)
Article DOI: 10.1016/j.bmcl.2007.10.100 BindingDB Entry DOI: 10.7270/Q2348M63 |
More data for this Ligand-Target Pair | |
Huntingtin
(Homo sapiens (Human)) | BDBM50097114
![PNG](/data/jpeg/tenK5009/BindingDB_50097114.png) (6-chloro-N-(4-chlorophenethyl)quinazolin-4-amine |...)Show InChI InChI=1S/C16H13Cl2N3/c17-12-3-1-11(2-4-12)7-8-19-16-14-9-13(18)5-6-15(14)20-10-21-16/h1-6,9-10H,7-8H2,(H,19,20,21) | PDB
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| Article PubMed
| n/a | n/a | 3.44E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University
Curated by ChEMBL
| Assay Description Inhibition of Huntingtin protein aggregation by cell based assay |
Bioorg Med Chem Lett 19: 1715-7 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.087 BindingDB Entry DOI: 10.7270/Q2Q2403P |
More data for this Ligand-Target Pair | |
Transcription factor p65
(Homo sapiens (Human)) | BDBM50372518
![PNG](/data/jpeg/tenK5037/BindingDB_50372518.png) (CHEMBL257234)Show InChI InChI=1S/C13H10N2O2S2/c16-19(17,12-7-3-9-18-12)15-11-6-1-4-10-5-2-8-14-13(10)11/h1-9,15H | PDB
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Similars
| Article PubMed
| n/a | n/a | 3.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University
Curated by ChEMBL
| Assay Description Inhibition of TNF-alpha-stimulated human NF-kappaB p65 RelA subunit nuclear translocation in HUVEC |
Bioorg Med Chem Lett 18: 329-35 (2008)
Article DOI: 10.1016/j.bmcl.2007.10.100 BindingDB Entry DOI: 10.7270/Q2348M63 |
More data for this Ligand-Target Pair | |
Huntingtin
(Homo sapiens (Human)) | BDBM50258234
![PNG](/data/jpeg/tenK5025/BindingDB_50258234.png) (6-chloro-4-(4-ethylpiperazin-1-yl)quinazoline | CH...)Show InChI InChI=1S/C14H17ClN4/c1-2-18-5-7-19(8-6-18)14-12-9-11(15)3-4-13(12)16-10-17-14/h3-4,9-10H,2,5-8H2,1H3 | PDB
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| Article PubMed
| n/a | n/a | 3.63E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University
Curated by ChEMBL
| Assay Description Inhibition of Huntingtin protein aggregation by cell based assay |
Bioorg Med Chem Lett 19: 1715-7 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.087 BindingDB Entry DOI: 10.7270/Q2Q2403P |
More data for this Ligand-Target Pair | |
Transcription factor p65
(Homo sapiens (Human)) | BDBM50372511
![PNG](/data/jpeg/tenK5037/BindingDB_50372511.png) (CHEMBL404588)Show SMILES [O-][N+](=O)c1cc(ccc1S(=O)(=O)Nc1cccc2cccnc12)C(F)(F)F Show InChI InChI=1S/C16H10F3N3O4S/c17-16(18,19)11-6-7-14(13(9-11)22(23)24)27(25,26)21-12-5-1-3-10-4-2-8-20-15(10)12/h1-9,21H | PDB
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Similars
| Article PubMed
| n/a | n/a | 3.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University
Curated by ChEMBL
| Assay Description Inhibition of TNF-alpha-stimulated human NF-kappaB p65 RelA subunit nuclear translocation in HUVEC |
Bioorg Med Chem Lett 18: 329-35 (2008)
Article DOI: 10.1016/j.bmcl.2007.10.100 BindingDB Entry DOI: 10.7270/Q2348M63 |
More data for this Ligand-Target Pair | |
Transcription factor p65
(Homo sapiens (Human)) | BDBM50372513
![PNG](/data/jpeg/tenK5037/BindingDB_50372513.png) (CHEMBL256204)Show SMILES Cc1ccc2cccc(NS(=O)(=O)c3ccccc3[N+]([O-])=O)c2n1 Show InChI InChI=1S/C16H13N3O4S/c1-11-9-10-12-5-4-6-13(16(12)17-11)18-24(22,23)15-8-3-2-7-14(15)19(20)21/h2-10,18H,1H3 | PDB
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Similars
| Article PubMed
| n/a | n/a | 3.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University
Curated by ChEMBL
| Assay Description Inhibition of TNF-alpha-stimulated human NF-kappaB p65 RelA subunit nuclear translocation in HUVEC |
Bioorg Med Chem Lett 18: 329-35 (2008)
Article DOI: 10.1016/j.bmcl.2007.10.100 BindingDB Entry DOI: 10.7270/Q2348M63 |
More data for this Ligand-Target Pair | |
Huntingtin
(Homo sapiens (Human)) | BDBM50257748
![PNG](/data/jpeg/tenK5025/BindingDB_50257748.png) (4-(4-(6-chloroquinazolin-4-ylamino)butoxy)phenyl a...)Show InChI InChI=1S/C20H20ClN3O3/c1-2-26-19(25)12-27-16-6-3-14(4-7-16)9-10-22-20-17-11-15(21)5-8-18(17)23-13-24-20/h3-8,11,13H,2,9-10,12H2,1H3,(H,22,23,24) | PDB
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| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 4.48E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University
Curated by ChEMBL
| Assay Description Inhibition of Huntingtin protein aggregation by cell based assay |
Bioorg Med Chem Lett 19: 1715-7 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.087 BindingDB Entry DOI: 10.7270/Q2Q2403P |
More data for this Ligand-Target Pair | |
Huntingtin
(Homo sapiens (Human)) | BDBM50258235
![PNG](/data/jpeg/tenK5025/BindingDB_50258235.png) (4-(4-ethylpiperazin-1-yl)-6-fluoroquinazoline | CH...)Show InChI InChI=1S/C14H17FN4/c1-2-18-5-7-19(8-6-18)14-12-9-11(15)3-4-13(12)16-10-17-14/h3-4,9-10H,2,5-8H2,1H3 | PDB
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Similars
| Article PubMed
| n/a | n/a | 5.26E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University
Curated by ChEMBL
| Assay Description Inhibition of Huntingtin protein aggregation by cell based assay |
Bioorg Med Chem Lett 19: 1715-7 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.087 BindingDB Entry DOI: 10.7270/Q2Q2403P |
More data for this Ligand-Target Pair | |
Huntingtin
(Homo sapiens (Human)) | BDBM50257750
![PNG](/data/jpeg/tenK5025/BindingDB_50257750.png) (CHEMBL494325 | N-allyl-6-bromoquinazolin-4-amine |...)Show InChI InChI=1S/C11H10BrN3/c1-2-5-13-11-9-6-8(12)3-4-10(9)14-7-15-11/h2-4,6-7H,1,5H2,(H,13,14,15) | PDB
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Similars
| Article PubMed
| n/a | n/a | 5.36E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University
Curated by ChEMBL
| Assay Description Inhibition of Huntingtin protein aggregation by cell based assay |
Bioorg Med Chem Lett 19: 1715-7 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.087 BindingDB Entry DOI: 10.7270/Q2Q2403P |
More data for this Ligand-Target Pair | |
Huntingtin
(Homo sapiens (Human)) | BDBM50257751
![PNG](/data/jpeg/tenK5025/BindingDB_50257751.png) (CHEMBL494326 | N-benzyl-6-bromoquinazolin-4-amine ...)Show InChI InChI=1S/C15H12BrN3/c16-12-6-7-14-13(8-12)15(19-10-18-14)17-9-11-4-2-1-3-5-11/h1-8,10H,9H2,(H,17,18,19) | PDB
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Similars
| Article PubMed
| n/a | n/a | 6.13E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University
Curated by ChEMBL
| Assay Description Inhibition of Huntingtin protein aggregation by cell based assay |
Bioorg Med Chem Lett 19: 1715-7 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.087 BindingDB Entry DOI: 10.7270/Q2Q2403P |
More data for this Ligand-Target Pair | |
Huntingtin
(Homo sapiens (Human)) | BDBM50257651
![PNG](/data/jpeg/tenK5025/BindingDB_50257651.png) (4-(2-(6-fluoroquinazolin-4-ylamino)ethyl)phenol | ...)Show InChI InChI=1S/C16H14FN3O/c17-12-3-6-15-14(9-12)16(20-10-19-15)18-8-7-11-1-4-13(21)5-2-11/h1-6,9-10,21H,7-8H2,(H,18,19,20) | PDB
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Similars
| Article PubMed
| n/a | n/a | 6.38E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University
Curated by ChEMBL
| Assay Description Inhibition of Huntingtin protein aggregation by cell based assay |
Bioorg Med Chem Lett 19: 1715-7 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.087 BindingDB Entry DOI: 10.7270/Q2Q2403P |
More data for this Ligand-Target Pair | |
Huntingtin
(Homo sapiens (Human)) | BDBM50257749
![PNG](/data/jpeg/tenK5025/BindingDB_50257749.png) (6-bromo-N-propylquinazolin-4-amine | CHEMBL449571)Show InChI InChI=1S/C11H12BrN3/c1-2-5-13-11-9-6-8(12)3-4-10(9)14-7-15-11/h3-4,6-7H,2,5H2,1H3,(H,13,14,15) | PDB
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Similars
| Article PubMed
| n/a | n/a | 8.13E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University
Curated by ChEMBL
| Assay Description Inhibition of Huntingtin protein aggregation by cell based assay |
Bioorg Med Chem Lett 19: 1715-7 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.087 BindingDB Entry DOI: 10.7270/Q2Q2403P |
More data for this Ligand-Target Pair | |
Transcription factor p65
(Homo sapiens (Human)) | BDBM50372508
![PNG](/data/jpeg/tenK5037/BindingDB_50372508.png) (CHEMBL256244)Show InChI InChI=1S/C18H18N2O3S/c1-12-4-8-16(9-5-12)24(21,22)20-17-11-15(23-3)10-14-7-6-13(2)19-18(14)17/h4-11,20H,1-3H3 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University
Curated by ChEMBL
| Assay Description Inhibition of TNF-alpha-stimulated human NF-kappaB p65 RelA subunit nuclear translocation in HUVEC |
Bioorg Med Chem Lett 18: 329-35 (2008)
Article DOI: 10.1016/j.bmcl.2007.10.100 BindingDB Entry DOI: 10.7270/Q2348M63 |
More data for this Ligand-Target Pair | |
Transcription factor p65
(Homo sapiens (Human)) | BDBM50372515
![PNG](/data/jpeg/tenK5037/BindingDB_50372515.png) (CHEMBL403333)Show InChI InChI=1S/C16H12N2O3S/c1-9-2-3-10-4-6-12-13-8-11(19)5-7-14(13)22(20,21)18-16(12)15(10)17-9/h2-8,18-19H,1H3 | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University
Curated by ChEMBL
| Assay Description Inhibition of TNF-alpha-stimulated human NF-kappaB p65 RelA subunit nuclear translocation in HUVEC |
Bioorg Med Chem Lett 18: 329-35 (2008)
Article DOI: 10.1016/j.bmcl.2007.10.100 BindingDB Entry DOI: 10.7270/Q2348M63 |
More data for this Ligand-Target Pair | |
Transcription factor p65
(Homo sapiens (Human)) | BDBM50227494
![PNG](/data/jpeg/tenK5022/BindingDB_50227494.png) (CHEMBL257286 | N-(quinolin-8-yl)benzenesulfonamide...)Show InChI InChI=1S/C15H12N2O2S/c18-20(19,13-8-2-1-3-9-13)17-14-10-4-6-12-7-5-11-16-15(12)14/h1-11,17H | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| Purchase
CHEMBL MCE PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University
Curated by ChEMBL
| Assay Description Inhibition of TNF-alpha-stimulated human NF-kappaB p65 RelA subunit nuclear translocation in HUVEC |
Bioorg Med Chem Lett 18: 329-35 (2008)
Article DOI: 10.1016/j.bmcl.2007.10.100 BindingDB Entry DOI: 10.7270/Q2348M63 |
More data for this Ligand-Target Pair | |
Huntingtin
(Homo sapiens (Human)) | BDBM50257495
![PNG](/data/jpeg/tenK5025/BindingDB_50257495.png) (6-fluoro-4-(4-methylpiperazin-1-yl)quinazoline | C...)Show InChI InChI=1S/C13H15FN4/c1-17-4-6-18(7-5-17)13-11-8-10(14)2-3-12(11)15-9-16-13/h2-3,8-9H,4-7H2,1H3 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University
Curated by ChEMBL
| Assay Description Inhibition of Huntingtin protein aggregation by cell based assay |
Bioorg Med Chem Lett 19: 1715-7 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.087 BindingDB Entry DOI: 10.7270/Q2Q2403P |
More data for this Ligand-Target Pair | |
Huntingtin
(Homo sapiens (Human)) | BDBM50257496
![PNG](/data/jpeg/tenK5025/BindingDB_50257496.png) (4-(4-methylpiperazin-1-yl)quinazoline | CHEMBL5069...)Show InChI InChI=1S/C13H16N4/c1-16-6-8-17(9-7-16)13-11-4-2-3-5-12(11)14-10-15-13/h2-5,10H,6-9H2,1H3 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| Purchase
CHEMBL MMDB PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University
Curated by ChEMBL
| Assay Description Inhibition of Huntingtin protein aggregation by cell based assay |
Bioorg Med Chem Lett 19: 1715-7 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.087 BindingDB Entry DOI: 10.7270/Q2Q2403P |
More data for this Ligand-Target Pair | |
Huntingtin
(Homo sapiens (Human)) | BDBM50257494
![PNG](/data/jpeg/tenK5025/BindingDB_50257494.png) (6-chloro-4-(4-methylpiperazin-1-yl)quinazoline | C...)Show InChI InChI=1S/C13H15ClN4/c1-17-4-6-18(7-5-17)13-11-8-10(14)2-3-12(11)15-9-16-13/h2-3,8-9H,4-7H2,1H3 | PDB
KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Columbia University
Curated by ChEMBL
| Assay Description Inhibition of Huntingtin protein aggregation by cell based assay |
Bioorg Med Chem Lett 19: 1715-7 (2009)
Article DOI: 10.1016/j.bmcl.2009.01.087 BindingDB Entry DOI: 10.7270/Q2Q2403P |
More data for this Ligand-Target Pair | |