Found 374 hits with Last Name = 'monck' and Initial = 'nj' Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
5-hydroxytryptamine receptor 2C
(Homo sapiens (Human)) | BDBM50169264
((4R,10aR)-7-Chloro-4,6-dimethyl-1,2,3,4,10,10a-hex...)Show InChI InChI=1S/C13H17ClN2/c1-8-6-15-7-11-5-10-3-4-12(14)9(2)13(10)16(8)11/h3-4,8,11,15H,5-7H2,1-2H3/t8-,11-/m1/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 0.300 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
F. Hoffmann-La Roche Ltd
Curated by ChEMBL
| Assay Description Displacement of [3H]-5HT from human recombinant 5HT2C receptor expressed in CHO cells |
Bioorg Med Chem Lett 16: 1207-11 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.083 BindingDB Entry DOI: 10.7270/Q21R6Q3T |
More data for this Ligand-Target Pair | |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM50200841
(CHEMBL220360 | MK-0364 | MK-0634 | N-((2S,3S)-4-(4...)Show SMILES C[C@H](NC(=O)C(C)(C)Oc1ccc(cn1)C(F)(F)F)[C@@H](Cc1ccc(Cl)cc1)c1cccc(c1)C#N |r| Show InChI InChI=1S/C27H25ClF3N3O2/c1-17(34-25(35)26(2,3)36-24-12-9-21(16-33-24)27(29,30)31)23(14-18-7-10-22(28)11-8-18)20-6-4-5-19(13-20)15-32/h4-13,16-17,23H,14H2,1-3H3,(H,34,35)/t17-,23+/m0/s1 | PDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid PDB UniChem
Patents
Similars
| PDB Article PubMed
| 0.300 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vernalis (R&D) Ltd
Curated by ChEMBL
| Assay Description Displacement of [3H]rimonabant from human CB1 receptor expressed in HEK293 cells by liquid scintillation counting |
Bioorg Med Chem Lett 19: 4183-90 (2009)
Article DOI: 10.1016/j.bmcl.2009.05.114 BindingDB Entry DOI: 10.7270/Q2XP75VT |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
5-hydroxytryptamine receptor 2C
(Homo sapiens (Human)) | BDBM50179077
((4R,9aR)-6-bromo-4-methyl-1,2,3,4,9,9a-hexahydro-2...)Show InChI InChI=1S/C11H14BrN3/c1-7-5-13-6-9-4-8-2-3-10(12)14-11(8)15(7)9/h2-3,7,9,13H,4-6H2,1H3/t7-,9-/m1/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 0.800 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
F. Hoffmann-La Roche Ltd
Curated by ChEMBL
| Assay Description Displacement of [3H]-5HT from human recombinant 5HT2C receptor expressed in CHO cells |
Bioorg Med Chem Lett 16: 1207-11 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.083 BindingDB Entry DOI: 10.7270/Q21R6Q3T |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 2C
(Homo sapiens (Human)) | BDBM50179080
((4R,9aR)-6-chloro-4-methyl-1,2,3,4,9,9a-hexahydro-...)Show InChI InChI=1S/C11H14ClN3/c1-7-5-13-6-9-4-8-2-3-10(12)14-11(8)15(7)9/h2-3,7,9,13H,4-6H2,1H3/t7-,9-/m1/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 1.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
F. Hoffmann-La Roche Ltd
Curated by ChEMBL
| Assay Description Displacement of [3H]-5HT from human recombinant 5HT2C receptor expressed in CHO cells |
Bioorg Med Chem Lett 16: 1207-11 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.083 BindingDB Entry DOI: 10.7270/Q21R6Q3T |
More data for this Ligand-Target Pair | |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM21278
(5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl...)Show SMILES Cc1c(nn(c1-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl)C(=O)NN1CCCCC1 Show InChI InChI=1S/C22H21Cl3N4O/c1-14-20(22(30)27-28-11-3-2-4-12-28)26-29(19-10-9-17(24)13-18(19)25)21(14)15-5-7-16(23)8-6-15/h5-10,13H,2-4,11-12H2,1H3,(H,27,30) | PDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem
Patents
Similars
| DrugBank Article PubMed
| 1.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vernalis (R&D) Ltd
Curated by PDSP Ki Database
| |
Bioorg Med Chem Lett 18: 1199-206 (2008)
Article DOI: 10.1016/j.bmcl.2007.11.133 BindingDB Entry DOI: 10.7270/Q20000N4 |
More data for this Ligand-Target Pair | |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM21278
(5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl...)Show SMILES Cc1c(nn(c1-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl)C(=O)NN1CCCCC1 Show InChI InChI=1S/C22H21Cl3N4O/c1-14-20(22(30)27-28-11-3-2-4-12-28)26-29(19-10-9-17(24)13-18(19)25)21(14)15-5-7-16(23)8-6-15/h5-10,13H,2-4,11-12H2,1H3,(H,27,30) | PDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem
Patents
Similars
| DrugBank Article PubMed
| 1.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vernalis (R&D) Ltd
Curated by ChEMBL
| Assay Description Displacement of [3H]rimonabant from human CB1 receptor expressed in HEK293 cells by liquid scintillation counting |
Bioorg Med Chem Lett 19: 4183-90 (2009)
Article DOI: 10.1016/j.bmcl.2009.05.114 BindingDB Entry DOI: 10.7270/Q2XP75VT |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 2C
(Homo sapiens (Human)) | BDBM50169261
((4R,10aS)-7-Chloro-4,6-dimethyl-1,2,3,4,10,10a-hex...)Show InChI InChI=1S/C13H17ClN2/c1-8-6-15-7-11-5-10-3-4-12(14)9(2)13(10)16(8)11/h3-4,8,11,15H,5-7H2,1-2H3/t8-,11+/m1/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 1.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
F. Hoffmann-La Roche Ltd
Curated by ChEMBL
| Assay Description Displacement of [3H]-5HT from human recombinant 5HT2C receptor expressed in CHO cells |
Bioorg Med Chem Lett 16: 1207-11 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.083 BindingDB Entry DOI: 10.7270/Q21R6Q3T |
More data for this Ligand-Target Pair | |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM50198507
(2-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-3-methyl...)Show SMILES Cc1c2c(CCN(N3CCCCC3)C2=O)n(c1-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl |(-4.72,3.29,;-4.23,1.83,;-2.75,1.36,;-2.75,-.19,;-1.41,-.96,;-.07,-.19,;-.07,1.36,;1.26,2.13,;2.6,1.34,;3.93,2.11,;3.94,3.65,;2.61,4.42,;1.26,3.66,;-1.41,2.14,;-1.41,3.68,;-4.22,-.67,;-5.13,.57,;-6.67,.56,;-7.45,1.88,;-8.98,1.87,;-9.74,.53,;-11.28,.52,;-8.96,-.8,;-7.42,-.78,;-4.68,-2.14,;-6.19,-2.46,;-6.66,-3.93,;-5.62,-5.07,;-6.09,-6.53,;-4.11,-4.73,;-3.65,-3.27,;-2.15,-2.93,)| Show InChI InChI=1S/C25H24Cl3N3O/c1-16-23-22(11-14-30(25(23)32)29-12-3-2-4-13-29)31(21-10-9-19(27)15-20(21)28)24(16)17-5-7-18(26)8-6-17/h5-10,15H,2-4,11-14H2,1H3 | PDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 2.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vernalis (R&D) Ltd
Curated by ChEMBL
| Assay Description Displacement of [3H]rimonabant from human CB1 receptor expressed in HEK293 cells by liquid scintillation counting |
Bioorg Med Chem Lett 19: 4183-90 (2009)
Article DOI: 10.1016/j.bmcl.2009.05.114 BindingDB Entry DOI: 10.7270/Q2XP75VT |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 2C
(Homo sapiens (Human)) | BDBM50179087
((4R,9aR)-6-[1-((S)-ethoxy)-ethyl]-4-methyl-1,2,3,4...)Show SMILES CCO[C@@H](C)c1ccc2C[C@@H]3CNC[C@@H](C)N3c2n1 Show InChI InChI=1S/C15H23N3O/c1-4-19-11(3)14-6-5-12-7-13-9-16-8-10(2)18(13)15(12)17-14/h5-6,10-11,13,16H,4,7-9H2,1-3H3/t10-,11+,13-/m1/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 2.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
F. Hoffmann-La Roche Ltd
Curated by ChEMBL
| Assay Description Displacement of [3H]-5HT from human recombinant 5HT2C receptor expressed in CHO cells |
Bioorg Med Chem Lett 16: 1207-11 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.083 BindingDB Entry DOI: 10.7270/Q21R6Q3T |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 2C
(Homo sapiens (Human)) | BDBM50144841
((S)-1-(6-chloro-5-fluoro-1H-indol-1-yl)propan-2-am...)Show InChI InChI=1S/C11H12ClFN2/c1-7(14)6-15-3-2-8-4-10(13)9(12)5-11(8)15/h2-5,7H,6,14H2,1H3/t7-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 2.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vernalis Research Ltd
Curated by ChEMBL
| Assay Description Affinity for human 5-hydroxytryptamine 2C receptor expressed in mammalian cell line |
Bioorg Med Chem Lett 14: 2367-70 (2004)
Article DOI: 10.1016/j.bmcl.2003.05.001 BindingDB Entry DOI: 10.7270/Q22B8XG5 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 2A
(Homo sapiens (Human)) | BDBM50169264
((4R,10aR)-7-Chloro-4,6-dimethyl-1,2,3,4,10,10a-hex...)Show InChI InChI=1S/C13H17ClN2/c1-8-6-15-7-11-5-10-3-4-12(14)9(2)13(10)16(8)11/h3-4,8,11,15H,5-7H2,1-2H3/t8-,11-/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 2.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
F. Hoffmann-La Roche Ltd
Curated by ChEMBL
| Assay Description Displacement of [125I]DOI from human recombinant 5HT2A receptor expressed in CHO cells |
Bioorg Med Chem Lett 16: 1207-11 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.083 BindingDB Entry DOI: 10.7270/Q21R6Q3T |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 2C
(Homo sapiens (Human)) | BDBM50179086
((4R,9aR)-4,6-dimethyl-1,2,3,4,9,9a-hexahydro-2,4a,...)Show InChI InChI=1S/C12H17N3/c1-8-3-4-10-5-11-7-13-6-9(2)15(11)12(10)14-8/h3-4,9,11,13H,5-7H2,1-2H3/t9-,11-/m1/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 2.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
F. Hoffmann-La Roche Ltd
Curated by ChEMBL
| Assay Description Displacement of [3H]-5HT from human recombinant 5HT2C receptor expressed in CHO cells |
Bioorg Med Chem Lett 16: 1207-11 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.083 BindingDB Entry DOI: 10.7270/Q21R6Q3T |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 2C
(Homo sapiens (Human)) | BDBM50144846
((S)-2-(5-Fluoro-6-methylsulfanyl-2,3-dihydro-indol...)Show InChI InChI=1S/C12H17FN2S/c1-8(14)7-15-4-3-9-5-10(13)12(16-2)6-11(9)15/h5-6,8H,3-4,7,14H2,1-2H3/t8-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 3.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vernalis Research Ltd
Curated by ChEMBL
| Assay Description Affinity for human 5-hydroxytryptamine 2C receptor expressed in mammalian cell line |
Bioorg Med Chem Lett 14: 2367-70 (2004)
Article DOI: 10.1016/j.bmcl.2003.05.001 BindingDB Entry DOI: 10.7270/Q22B8XG5 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 2B
(Homo sapiens (Human)) | BDBM50169264
((4R,10aR)-7-Chloro-4,6-dimethyl-1,2,3,4,10,10a-hex...)Show InChI InChI=1S/C13H17ClN2/c1-8-6-15-7-11-5-10-3-4-12(14)9(2)13(10)16(8)11/h3-4,8,11,15H,5-7H2,1-2H3/t8-,11-/m1/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 3.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
F. Hoffmann-La Roche Ltd
Curated by ChEMBL
| Assay Description Displacement of [3H]-5HT from human recombinant 5HT2B receptor expressed in CHO cells |
Bioorg Med Chem Lett 16: 1207-11 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.083 BindingDB Entry DOI: 10.7270/Q21R6Q3T |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 2C
(Homo sapiens (Human)) | BDBM50179073
((4R,9aR)-6-Cyclopropylmethoxymethyl-4-methyl-1,2,3...)Show InChI InChI=1S/C16H23N3O/c1-11-7-17-8-15-6-13-4-5-14(18-16(13)19(11)15)10-20-9-12-2-3-12/h4-5,11-12,15,17H,2-3,6-10H2,1H3/t11-,15-/m1/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 3.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
F. Hoffmann-La Roche Ltd
Curated by ChEMBL
| Assay Description Displacement of [3H]-5HT from human recombinant 5HT2C receptor expressed in CHO cells |
Bioorg Med Chem Lett 16: 1207-11 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.083 BindingDB Entry DOI: 10.7270/Q21R6Q3T |
More data for this Ligand-Target Pair | |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM29094
((+/-)-SLV319 | (S)-3-(4-chlorophenyl)-N-(4-chlorop...)Show SMILES CN=C(NS(=O)(=O)c1ccc(Cl)cc1)N1CC(C(=N1)c1ccc(Cl)cc1)c1ccccc1 |w:1.0,c:18| Show InChI InChI=1S/C23H20Cl2N4O2S/c1-26-23(28-32(30,31)20-13-11-19(25)12-14-20)29-15-21(16-5-3-2-4-6-16)22(27-29)17-7-9-18(24)10-8-17/h2-14,21H,15H2,1H3,(H,26,28) | PDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 4.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vernalis (R&D) Ltd
Curated by PDSP Ki Database
| |
Bioorg Med Chem Lett 18: 1199-206 (2008)
Article DOI: 10.1016/j.bmcl.2007.11.133 BindingDB Entry DOI: 10.7270/Q20000N4 |
More data for this Ligand-Target Pair | |
Cannabinoid receptor 1
(Homo sapiens (Human)) | BDBM86887
(5-(3,5-dimethylpiperidin-1-ylsulfonyl)-3-methyl-N-...)Show SMILES CC1CC(C)CN(C1)S(=O)(=O)c1ccc2oc(C(=O)NC3CCCc4ccccc34)c(C)c2c1 Show InChI InChI=1S/C27H32N2O4S/c1-17-13-18(2)16-29(15-17)34(31,32)21-11-12-25-23(14-21)19(3)26(33-25)27(30)28-24-10-6-8-20-7-4-5-9-22(20)24/h4-5,7,9,11-12,14,17-18,24H,6,8,10,13,15-16H2,1-3H3,(H,28,30) | PDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
Similars
| Article PubMed
| 5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vernalis (R&D) Ltd
Curated by PDSP Ki Database
| |
Bioorg Med Chem Lett 18: 1199-206 (2008)
Article DOI: 10.1016/j.bmcl.2007.11.133 BindingDB Entry DOI: 10.7270/Q20000N4 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 2B
(Homo sapiens (Human)) | BDBM50144841
((S)-1-(6-chloro-5-fluoro-1H-indol-1-yl)propan-2-am...)Show InChI InChI=1S/C11H12ClFN2/c1-7(14)6-15-3-2-8-4-10(13)9(12)5-11(8)15/h2-5,7H,6,14H2,1H3/t7-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 5.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vernalis Research Ltd
Curated by ChEMBL
| Assay Description Affinity for human 5-hydroxytryptamine 2B receptor expressed in mammalian cell line |
Bioorg Med Chem Lett 14: 2367-70 (2004)
Article DOI: 10.1016/j.bmcl.2003.05.001 BindingDB Entry DOI: 10.7270/Q22B8XG5 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 2C
(Homo sapiens (Human)) | BDBM50144835
((S)-1-Methyl-2-(6-methylsulfanyl-2,3-dihydro-indol...)Show InChI InChI=1S/C12H18N2S/c1-9(13)8-14-6-5-10-3-4-11(15-2)7-12(10)14/h3-4,7,9H,5-6,8,13H2,1-2H3/t9-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 5.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vernalis Research Ltd
Curated by ChEMBL
| Assay Description Affinity for human 5-hydroxytryptamine 2C receptor expressed in mammalian cell line |
Bioorg Med Chem Lett 14: 2367-70 (2004)
Article DOI: 10.1016/j.bmcl.2003.05.001 BindingDB Entry DOI: 10.7270/Q22B8XG5 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 2C
(Homo sapiens (Human)) | BDBM50144839
((S)-2-(6-Ethylsulfanyl-5-fluoro-2,3-dihydro-indol-...)Show InChI InChI=1S/C13H19FN2S/c1-3-17-13-7-12-10(6-11(13)14)4-5-16(12)8-9(2)15/h6-7,9H,3-5,8,15H2,1-2H3/t9-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 6.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vernalis Research Ltd
Curated by ChEMBL
| Assay Description Affinity for human 5-hydroxytryptamine 2B receptor expressed in mammalian cell line |
Bioorg Med Chem Lett 14: 2367-70 (2004)
Article DOI: 10.1016/j.bmcl.2003.05.001 BindingDB Entry DOI: 10.7270/Q22B8XG5 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 2C
(Homo sapiens (Human)) | BDBM10755
(14C-5-hydroxy tryptamine creatinine disulfate | 2-...)Show InChI InChI=1S/C10H12N2O/c11-4-3-7-6-12-10-2-1-8(13)5-9(7)10/h1-2,5-6,12-13H,3-4,11H2 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL MCE KEGG PC cid PC sid PDB UniChem
Similars
| Article PubMed
| 6.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vernalis Research Ltd
Curated by ChEMBL
| Assay Description Affinity for human 5-hydroxytryptamine 2B receptor expressed in mammalian cell line |
Bioorg Med Chem Lett 14: 2367-70 (2004)
Article DOI: 10.1016/j.bmcl.2003.05.001 BindingDB Entry DOI: 10.7270/Q22B8XG5 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 2C
(Homo sapiens (Human)) | BDBM50144842
((S)-1-Methyl-2-(2,3,7,8-tetrahydro-furo[2,3-g]indo...)Show InChI InChI=1S/C13H18N2O/c1-9(14)8-15-6-4-10-2-3-12-11(13(10)15)5-7-16-12/h2-3,9H,4-8,14H2,1H3/t9-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 8.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vernalis Research Ltd
Curated by ChEMBL
| Assay Description Affinity for human 5-hydroxytryptamine 2C receptor expressed in mammalian cell line |
Bioorg Med Chem Lett 14: 2367-70 (2004)
Article DOI: 10.1016/j.bmcl.2003.05.001 BindingDB Entry DOI: 10.7270/Q22B8XG5 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 2C
(Homo sapiens (Human)) | BDBM50001915
(1-(3-chlorophenyl)piperazine | CHEMBL478 | m-Chlor...)Show InChI InChI=1S/C10H13ClN2/c11-9-2-1-3-10(8-9)13-6-4-12-5-7-13/h1-3,8,12H,4-7H2 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL KEGG PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 9 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vernalis Research Ltd
Curated by ChEMBL
| Assay Description Affinity for human 5-hydroxytryptamine 2A receptor expressed in mammalian cell line |
Bioorg Med Chem Lett 14: 2367-70 (2004)
Article DOI: 10.1016/j.bmcl.2003.05.001 BindingDB Entry DOI: 10.7270/Q22B8XG5 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 2B
(Homo sapiens (Human)) | BDBM10755
(14C-5-hydroxy tryptamine creatinine disulfate | 2-...)Show InChI InChI=1S/C10H12N2O/c11-4-3-7-6-12-10-2-1-8(13)5-9(7)10/h1-2,5-6,12-13H,3-4,11H2 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE KEGG PC cid PC sid PDB UniChem
Similars
| Article PubMed
| 12 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vernalis Research Ltd
Curated by ChEMBL
| Assay Description Affinity for human 5-hydroxytryptamine 2B receptor expressed in mammalian cell line |
Bioorg Med Chem Lett 14: 2367-70 (2004)
Article DOI: 10.1016/j.bmcl.2003.05.001 BindingDB Entry DOI: 10.7270/Q22B8XG5 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 2C
(Homo sapiens (Human)) | BDBM50144837
((S)-2-(6-Chloro-2,3-dihydro-indol-1-yl)-1-methyl-e...)Show InChI InChI=1S/C11H15ClN2/c1-8(13)7-14-5-4-9-2-3-10(12)6-11(9)14/h2-3,6,8H,4-5,7,13H2,1H3/t8-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 13 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vernalis Research Ltd
Curated by ChEMBL
| Assay Description Affinity for human 5-hydroxytryptamine 2C receptor expressed in mammalian cell line |
Bioorg Med Chem Lett 14: 2367-70 (2004)
Article DOI: 10.1016/j.bmcl.2003.05.001 BindingDB Entry DOI: 10.7270/Q22B8XG5 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 2A
(Homo sapiens (Human)) | BDBM10755
(14C-5-hydroxy tryptamine creatinine disulfate | 2-...)Show InChI InChI=1S/C10H12N2O/c11-4-3-7-6-12-10-2-1-8(13)5-9(7)10/h1-2,5-6,12-13H,3-4,11H2 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE KEGG PC cid PC sid PDB UniChem
Similars
| Article PubMed
| 14 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vernalis Research Ltd
Curated by ChEMBL
| Assay Description Functional activity against human 5-hydroxytryptamine 2A receptor expressed in CHO cells using fluorometricimaging plate reader |
Bioorg Med Chem Lett 14: 2367-70 (2004)
Article DOI: 10.1016/j.bmcl.2003.05.001 BindingDB Entry DOI: 10.7270/Q22B8XG5 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 2C
(Homo sapiens (Human)) | BDBM50179079
((4R,9aR)-4-methyl-6-trifluoromethyl-1,2,3,4,9,9a-h...)Show InChI InChI=1S/C12H14F3N3/c1-7-5-16-6-9-4-8-2-3-10(12(13,14)15)17-11(8)18(7)9/h2-3,7,9,16H,4-6H2,1H3/t7-,9-/m1/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 14 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
F. Hoffmann-La Roche Ltd
Curated by ChEMBL
| Assay Description Displacement of [3H]-5HT from human recombinant 5HT2C receptor expressed in CHO cells |
Bioorg Med Chem Lett 16: 1207-11 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.083 BindingDB Entry DOI: 10.7270/Q21R6Q3T |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 2C
(Homo sapiens (Human)) | BDBM50144845
((S)-2-(6-Chloro-5-fluoro-2,3-dihydro-indol-1-yl)-1...)Show InChI InChI=1S/C11H14ClFN2/c1-7(14)6-15-3-2-8-4-10(13)9(12)5-11(8)15/h4-5,7H,2-3,6,14H2,1H3/t7-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 14 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vernalis Research Ltd
Curated by ChEMBL
| Assay Description Affinity for human 5-hydroxytryptamine 2B receptor expressed in mammalian cell line |
Bioorg Med Chem Lett 14: 2367-70 (2004)
Article DOI: 10.1016/j.bmcl.2003.05.001 BindingDB Entry DOI: 10.7270/Q22B8XG5 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 2C
(Homo sapiens (Human)) | BDBM50179078
((4R,9aR)-6-methoxymethyl-4-methyl-1,2,3,4,9,9a-hex...)Show InChI InChI=1S/C13H19N3O/c1-9-6-14-7-12-5-10-3-4-11(8-17-2)15-13(10)16(9)12/h3-4,9,12,14H,5-8H2,1-2H3/t9-,12-/m1/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 16 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
F. Hoffmann-La Roche Ltd
Curated by ChEMBL
| Assay Description Displacement of [3H]-5HT from human recombinant 5HT2C receptor expressed in CHO cells |
Bioorg Med Chem Lett 16: 1207-11 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.083 BindingDB Entry DOI: 10.7270/Q21R6Q3T |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 2C
(Homo sapiens (Human)) | BDBM50144836
((S)-2-(6-Ethylsulfanyl-2,3-dihydro-indol-1-yl)-1-m...)Show InChI InChI=1S/C13H20N2S/c1-3-16-12-5-4-11-6-7-15(9-10(2)14)13(11)8-12/h4-5,8,10H,3,6-7,9,14H2,1-2H3/t10-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 16 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vernalis Research Ltd
Curated by ChEMBL
| Assay Description Functional activity against human 5-hydroxytryptamine 2C receptor expressed in CHO cells using fluorometricimaging plate reader |
Bioorg Med Chem Lett 14: 2367-70 (2004)
Article DOI: 10.1016/j.bmcl.2003.05.001 BindingDB Entry DOI: 10.7270/Q22B8XG5 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 2C
(Homo sapiens (Human)) | BDBM50144838
((S)-2-(5-Fluoro-6-iodo-2,3-dihydro-indol-1-yl)-1-m...)Show InChI InChI=1S/C11H14FIN2/c1-7(14)6-15-3-2-8-4-9(12)10(13)5-11(8)15/h4-5,7H,2-3,6,14H2,1H3/t7-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
| Article PubMed
| 17 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vernalis Research Ltd
Curated by ChEMBL
| Assay Description Affinity for human 5-hydroxytryptamine 2C receptor expressed in mammalian cell line |
Bioorg Med Chem Lett 14: 2367-70 (2004)
Article DOI: 10.1016/j.bmcl.2003.05.001 BindingDB Entry DOI: 10.7270/Q22B8XG5 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 2A
(Homo sapiens (Human)) | BDBM50169261
((4R,10aS)-7-Chloro-4,6-dimethyl-1,2,3,4,10,10a-hex...)Show InChI InChI=1S/C13H17ClN2/c1-8-6-15-7-11-5-10-3-4-12(14)9(2)13(10)16(8)11/h3-4,8,11,15H,5-7H2,1-2H3/t8-,11+/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 19 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
F. Hoffmann-La Roche Ltd
Curated by ChEMBL
| Assay Description Displacement of [125I]DOI from human recombinant 5HT2A receptor expressed in CHO cells |
Bioorg Med Chem Lett 16: 1207-11 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.083 BindingDB Entry DOI: 10.7270/Q21R6Q3T |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 2C
(Homo sapiens (Human)) | BDBM50179076
((4R,9aS)-6-bromo-4-methyl-1,2,3,4,9,9a-hexahydro-2...)Show InChI InChI=1S/C11H14BrN3/c1-7-5-13-6-9-4-8-2-3-10(12)14-11(8)15(7)9/h2-3,7,9,13H,4-6H2,1H3/t7-,9+/m1/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 21 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
F. Hoffmann-La Roche Ltd
Curated by ChEMBL
| Assay Description Displacement of [3H]-5HT from human recombinant 5HT2C receptor expressed in CHO cells |
Bioorg Med Chem Lett 16: 1207-11 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.083 BindingDB Entry DOI: 10.7270/Q21R6Q3T |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 2B
(Homo sapiens (Human)) | BDBM50144846
((S)-2-(5-Fluoro-6-methylsulfanyl-2,3-dihydro-indol...)Show InChI InChI=1S/C12H17FN2S/c1-8(14)7-15-4-3-9-5-10(13)12(16-2)6-11(9)15/h5-6,8H,3-4,7,14H2,1-2H3/t8-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 21 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vernalis Research Ltd
Curated by ChEMBL
| Assay Description Affinity for human 5-hydroxytryptamine 2B receptor expressed in mammalian cell line |
Bioorg Med Chem Lett 14: 2367-70 (2004)
Article DOI: 10.1016/j.bmcl.2003.05.001 BindingDB Entry DOI: 10.7270/Q22B8XG5 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 2C
(Homo sapiens (Human)) | BDBM50144840
((S)-2-(6-Bromo-2,3-dihydro-indol-1-yl)-1-methyl-et...)Show InChI InChI=1S/C11H15BrN2/c1-8(13)7-14-5-4-9-2-3-10(12)6-11(9)14/h2-3,6,8H,4-5,7,13H2,1H3/t8-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Patents
| Article PubMed
| 24 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vernalis Research Ltd
Curated by ChEMBL
| Assay Description Functional activity against human 5-hydroxytryptamine 2C receptor expressed in CHO cells using fluorometricimaging plate reader |
Bioorg Med Chem Lett 14: 2367-70 (2004)
Article DOI: 10.1016/j.bmcl.2003.05.001 BindingDB Entry DOI: 10.7270/Q22B8XG5 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 2C
(Homo sapiens (Human)) | BDBM50144843
((S)-2-(5-Fluoro-6-trifluoromethyl-2,3-dihydro-indo...)Show InChI InChI=1S/C12H14F4N2/c1-7(17)6-18-3-2-8-4-10(13)9(5-11(8)18)12(14,15)16/h4-5,7H,2-3,6,17H2,1H3/t7-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
| Article PubMed
| 26 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vernalis Research Ltd
Curated by ChEMBL
| Assay Description Affinity for human 5-hydroxytryptamine 2C receptor expressed in mammalian cell line |
Bioorg Med Chem Lett 14: 2367-70 (2004)
Article DOI: 10.1016/j.bmcl.2003.05.001 BindingDB Entry DOI: 10.7270/Q22B8XG5 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 2B
(Homo sapiens (Human)) | BDBM50144845
((S)-2-(6-Chloro-5-fluoro-2,3-dihydro-indol-1-yl)-1...)Show InChI InChI=1S/C11H14ClFN2/c1-7(14)6-15-3-2-8-4-10(13)9(12)5-11(8)15/h4-5,7H,2-3,6,14H2,1H3/t7-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 31 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vernalis Research Ltd
Curated by ChEMBL
| Assay Description Affinity for human 5-hydroxytryptamine 2A receptor expressed in mammalian cell line |
Bioorg Med Chem Lett 14: 2367-70 (2004)
Article DOI: 10.1016/j.bmcl.2003.05.001 BindingDB Entry DOI: 10.7270/Q22B8XG5 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 2B
(Homo sapiens (Human)) | BDBM50001915
(1-(3-chlorophenyl)piperazine | CHEMBL478 | m-Chlor...)Show InChI InChI=1S/C10H13ClN2/c11-9-2-1-3-10(8-9)13-6-4-12-5-7-13/h1-3,8,12H,4-7H2 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL KEGG PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 32 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vernalis Research Ltd
Curated by ChEMBL
| Assay Description Affinity for human 5-hydroxytryptamine 2C receptor expressed in mammalian cell line |
Bioorg Med Chem Lett 14: 2367-70 (2004)
Article DOI: 10.1016/j.bmcl.2003.05.001 BindingDB Entry DOI: 10.7270/Q22B8XG5 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 2B
(Homo sapiens (Human)) | BDBM50144838
((S)-2-(5-Fluoro-6-iodo-2,3-dihydro-indol-1-yl)-1-m...)Show InChI InChI=1S/C11H14FIN2/c1-7(14)6-15-3-2-8-4-9(12)10(13)5-11(8)15/h4-5,7H,2-3,6,14H2,1H3/t7-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
| Article PubMed
| 38 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vernalis Research Ltd
Curated by ChEMBL
| Assay Description Affinity for human 5-hydroxytryptamine 2C receptor expressed in mammalian cell line |
Bioorg Med Chem Lett 14: 2367-70 (2004)
Article DOI: 10.1016/j.bmcl.2003.05.001 BindingDB Entry DOI: 10.7270/Q22B8XG5 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 2A
(Homo sapiens (Human)) | BDBM50144841
((S)-1-(6-chloro-5-fluoro-1H-indol-1-yl)propan-2-am...)Show InChI InChI=1S/C11H12ClFN2/c1-7(14)6-15-3-2-8-4-10(13)9(12)5-11(8)15/h2-5,7H,6,14H2,1H3/t7-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 38 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vernalis Research Ltd
Curated by ChEMBL
| Assay Description Functional activity against human 5-hydroxytryptamine 2C receptor expressed in CHO cells using fluorometricimaging plate reader |
Bioorg Med Chem Lett 14: 2367-70 (2004)
Article DOI: 10.1016/j.bmcl.2003.05.001 BindingDB Entry DOI: 10.7270/Q22B8XG5 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 2C
(Homo sapiens (Human)) | BDBM50144844
((S)-1-Methyl-2-(2,3,8,9-tetrahydro-7H-pyrano[2,3-g...)Show InChI InChI=1S/C14H20N2O/c1-10(15)9-16-7-6-11-4-5-13-12(14(11)16)3-2-8-17-13/h4-5,10H,2-3,6-9,15H2,1H3/t10-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
| Article PubMed
| 38 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vernalis Research Ltd
Curated by ChEMBL
| Assay Description Affinity for human 5-hydroxytryptamine 2C receptor expressed in mammalian cell line |
Bioorg Med Chem Lett 14: 2367-70 (2004)
Article DOI: 10.1016/j.bmcl.2003.05.001 BindingDB Entry DOI: 10.7270/Q22B8XG5 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 2C
(Homo sapiens (Human)) | BDBM50179083
(1-((4R,9aR)-4-methyl-1,2,3,4,9,9a-hexahydro-2,4a,5...)Show InChI InChI=1S/C13H19N3O/c1-8-6-14-7-11-5-10-3-4-12(9(2)17)15-13(10)16(8)11/h3-4,8-9,11,14,17H,5-7H2,1-2H3/t8-,9+,11-/m1/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 39 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
F. Hoffmann-La Roche Ltd
Curated by ChEMBL
| Assay Description Displacement of [3H]-5HT from human recombinant 5HT2C receptor expressed in CHO cells |
Bioorg Med Chem Lett 16: 1207-11 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.083 BindingDB Entry DOI: 10.7270/Q21R6Q3T |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 2B
(Homo sapiens (Human)) | BDBM50169261
((4R,10aS)-7-Chloro-4,6-dimethyl-1,2,3,4,10,10a-hex...)Show InChI InChI=1S/C13H17ClN2/c1-8-6-15-7-11-5-10-3-4-12(14)9(2)13(10)16(8)11/h3-4,8,11,15H,5-7H2,1-2H3/t8-,11+/m1/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
F. Hoffmann-La Roche Ltd
Curated by ChEMBL
| Assay Description Displacement of [3H]-5HT from human recombinant 5HT2B receptor expressed in CHO cells |
Bioorg Med Chem Lett 16: 1207-11 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.083 BindingDB Entry DOI: 10.7270/Q21R6Q3T |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 2A
(Homo sapiens (Human)) | BDBM50179080
((4R,9aR)-6-chloro-4-methyl-1,2,3,4,9,9a-hexahydro-...)Show InChI InChI=1S/C11H14ClN3/c1-7-5-13-6-9-4-8-2-3-10(12)14-11(8)15(7)9/h2-3,7,9,13H,4-6H2,1H3/t7-,9-/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 42 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
F. Hoffmann-La Roche Ltd
Curated by ChEMBL
| Assay Description Displacement of [125I]DOI from human recombinant 5HT2A receptor expressed in CHO cells |
Bioorg Med Chem Lett 16: 1207-11 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.083 BindingDB Entry DOI: 10.7270/Q21R6Q3T |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 2A
(Homo sapiens (Human)) | BDBM50179079
((4R,9aR)-4-methyl-6-trifluoromethyl-1,2,3,4,9,9a-h...)Show InChI InChI=1S/C12H14F3N3/c1-7-5-16-6-9-4-8-2-3-10(12(13,14)15)17-11(8)18(7)9/h2-3,7,9,16H,4-6H2,1H3/t7-,9-/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 43 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
F. Hoffmann-La Roche Ltd
Curated by ChEMBL
| Assay Description Displacement of [125I]DOI from human recombinant 5HT2A receptor expressed in CHO cells |
Bioorg Med Chem Lett 16: 1207-11 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.083 BindingDB Entry DOI: 10.7270/Q21R6Q3T |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 2B
(Homo sapiens (Human)) | BDBM50144840
((S)-2-(6-Bromo-2,3-dihydro-indol-1-yl)-1-methyl-et...)Show InChI InChI=1S/C11H15BrN2/c1-8(13)7-14-5-4-9-2-3-10(12)6-11(9)14/h2-3,6,8H,4-5,7,13H2,1H3/t8-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Patents
| Article PubMed
| 46 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vernalis Research Ltd
Curated by ChEMBL
| Assay Description Affinity for human 5-hydroxytryptamine 2B receptor expressed in mammalian cell line |
Bioorg Med Chem Lett 14: 2367-70 (2004)
Article DOI: 10.1016/j.bmcl.2003.05.001 BindingDB Entry DOI: 10.7270/Q22B8XG5 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 2B
(Homo sapiens (Human)) | BDBM50179080
((4R,9aR)-6-chloro-4-methyl-1,2,3,4,9,9a-hexahydro-...)Show InChI InChI=1S/C11H14ClN3/c1-7-5-13-6-9-4-8-2-3-10(12)14-11(8)15(7)9/h2-3,7,9,13H,4-6H2,1H3/t7-,9-/m1/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 48 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
F. Hoffmann-La Roche Ltd
Curated by ChEMBL
| Assay Description Displacement of [3H]-5HT from human recombinant 5HT2B receptor expressed in CHO cells |
Bioorg Med Chem Lett 16: 1207-11 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.083 BindingDB Entry DOI: 10.7270/Q21R6Q3T |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 2B
(Homo sapiens (Human)) | BDBM50144842
((S)-1-Methyl-2-(2,3,7,8-tetrahydro-furo[2,3-g]indo...)Show InChI InChI=1S/C13H18N2O/c1-9(14)8-15-6-4-10-2-3-12-11(13(10)15)5-7-16-12/h2-3,9H,4-8,14H2,1H3/t9-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 49 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vernalis Research Ltd
Curated by ChEMBL
| Assay Description Functional activity against human 5-hydroxytryptamine 2B receptor expressed in CHO cells using fluorometricimaging plate reader |
Bioorg Med Chem Lett 14: 2367-70 (2004)
Article DOI: 10.1016/j.bmcl.2003.05.001 BindingDB Entry DOI: 10.7270/Q22B8XG5 |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 2C
(Homo sapiens (Human)) | BDBM50179081
((4R,9aS)-6-chloro-4-methyl-1,2,3,4,9,9a-hexahydro-...)Show InChI InChI=1S/C11H14ClN3/c1-7-5-13-6-9-4-8-2-3-10(12)14-11(8)15(7)9/h2-3,7,9,13H,4-6H2,1H3/t7-,9+/m1/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 52 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
F. Hoffmann-La Roche Ltd
Curated by ChEMBL
| Assay Description Displacement of [3H]-5HT from human recombinant 5HT2C receptor expressed in CHO cells |
Bioorg Med Chem Lett 16: 1207-11 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.083 BindingDB Entry DOI: 10.7270/Q21R6Q3T |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 2A
(Homo sapiens (Human)) | BDBM50179077
((4R,9aR)-6-bromo-4-methyl-1,2,3,4,9,9a-hexahydro-2...)Show InChI InChI=1S/C11H14BrN3/c1-7-5-13-6-9-4-8-2-3-10(12)14-11(8)15(7)9/h2-3,7,9,13H,4-6H2,1H3/t7-,9-/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 53 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
F. Hoffmann-La Roche Ltd
Curated by ChEMBL
| Assay Description Displacement of [125I]DOI from human recombinant 5HT2A receptor expressed in CHO cells |
Bioorg Med Chem Lett 16: 1207-11 (2006)
Article DOI: 10.1016/j.bmcl.2005.11.083 BindingDB Entry DOI: 10.7270/Q21R6Q3T |
More data for this Ligand-Target Pair | |