Compile Data Set for Download or QSAR

Found 40 hits with Last Name = 'shimmon' and Initial = 'r'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50066275 (CHEMBL3401548) Show SMILES OC(\C=C\c1ccccn1)c1ccccc1O Show InChI InChI=1S/C14H13NO2/c16-13-7-2-1-6-12(13)14(17)9-8-11-5-3-4-10-15-11/h1-10,14,16-17H/b9-8+	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.62E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Technology Sydney Curated by ChEMBL					Assay Description Competitive inhibition of mushroom tyrosinase assessed as inhibition of L-DOPA oxidase activity at 5 uM active compound by Lineweaver-Burk plot analy...				Bioorg Med Chem Lett 25: 1753-6 (2015) Article DOI: 10.1016/j.bmcl.2015.02.060 BindingDB Entry DOI: 10.7270/Q2T72K42
					More data for this Ligand-Target Pair
Membrane primary amine oxidase (Rattus norvegicus (Rat))	BDBM50104436 (((E)-3-Benzo[1,3]dioxol-5-yl-allyl)-methyl-amine |...) Show SMILES CNC\C=C\c1ccc2OCOc2c1 Show InChI InChI=1S/C11H13NO2/c1-12-6-2-3-9-4-5-10-11(7-9)14-8-13-10/h2-5,7,12H,6,8H2,1H3/b3-2+	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	2.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Technology Curated by ChEMBL					Assay Description Inhibitory activity of the compound against bovine plasma semicarbazide-sensitive amine oxidase (SSAO)				Bioorg Med Chem Lett 11: 2565-8 (2001) BindingDB Entry DOI: 10.7270/Q25T3JR2
					More data for this Ligand-Target Pair
Membrane primary amine oxidase (Rattus norvegicus (Rat))	BDBM50104437 (CHEMBL312832 | [3-(3,4-Dimethoxy-phenyl)-prop-2-yn...) Show SMILES COc1ccc(cc1OC)C#CCN(C)C Show InChI InChI=1S/C13H17NO2/c1-14(2)9-5-6-11-7-8-12(15-3)13(10-11)16-4/h7-8,10H,9H2,1-4H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	2.90E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Technology Curated by ChEMBL					Assay Description Inhibitory activity of the compound against bovine plasma semicarbazide-sensitive amine oxidase (SSAO)				Bioorg Med Chem Lett 11: 2565-8 (2001) BindingDB Entry DOI: 10.7270/Q25T3JR2
					More data for this Ligand-Target Pair
Membrane primary amine oxidase (Rattus norvegicus (Rat))	BDBM50104434 ((3-Benzo[1,3]dioxol-5-yl-prop-2-ynyl)-dimethyl-ami...) Show SMILES CN(C)CC#Cc1ccc2OCOc2c1 Show InChI InChI=1S/C12H13NO2/c1-13(2)7-3-4-10-5-6-11-12(8-10)15-9-14-11/h5-6,8H,7,9H2,1-2H3	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	3.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Technology Curated by ChEMBL					Assay Description Inhibitory activity of the compound against bovine plasma semicarbazide-sensitive amine oxidase (SSAO)				Bioorg Med Chem Lett 11: 2565-8 (2001) BindingDB Entry DOI: 10.7270/Q25T3JR2
					More data for this Ligand-Target Pair
Polyphenol oxidase 1 [N65D,S176D,K211T,P277A,P406L] (Agaricus bisporus (Mushroom))	BDBM173587 ((2E)-3-(3,5-dihydroxyphenyl)-1-(3-hydroxynaphthale...) Show SMILES Oc1cc(O)cc(\C=C\C(=O)c2cc3ccccc3cc2O)c1 Show InChI InChI=1S/C19H14O4/c20-15-7-12(8-16(21)11-15)5-6-18(22)17-9-13-3-1-2-4-14(13)10-19(17)23/h1-11,20-21,23H/b6-5+	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	3.80E+3	n/a	1.04E+4	n/a	n/a	n/a	n/a	6.8	n/a
University of Technology Sydney					Assay Description The mushroom tyrosinase inhibition activity of hydroxy naphthylchalcone compounds was measured using L-DOPA as substrate. The activity assay used 3 m...				Bioorg Chem 63: 116-22 (2015) Article DOI: 10.1016/j.bioorg.2015.10.003 BindingDB Entry DOI: 10.7270/Q2MS3RH3
					More data for this Ligand-Target Pair
Polyphenol oxidase 1 [N65D,S176D,K211T,P277A,P406L] (Agaricus bisporus (Mushroom))	BDBM173584 ((2E)-3-(2,4-dihydroxyphenyl)-1-(3-hydroxynaphthale...) Show SMILES Oc1ccc(\C=C\C(=O)c2cc3ccccc3cc2O)c(O)c1 Show InChI InChI=1S/C19H14O4/c20-15-7-5-12(18(22)11-15)6-8-17(21)16-9-13-3-1-2-4-14(13)10-19(16)23/h1-11,20,22-23H/b8-6+	UniProtKB/SwissProt GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars	Article PubMed	4.50E+3	n/a	1.44E+4	n/a	n/a	n/a	n/a	6.8	n/a
University of Technology Sydney					Assay Description The mushroom tyrosinase inhibition activity of hydroxy naphthylchalcone compounds was measured using L-DOPA as substrate. The activity assay used 3 m...				Bioorg Chem 63: 116-22 (2015) Article DOI: 10.1016/j.bioorg.2015.10.003 BindingDB Entry DOI: 10.7270/Q2MS3RH3
					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50121842 (CHEMBL3617039) Show SMILES O\N=C(/C=C/c1cccnc1)\c1cc2ccccc2cc1O Show InChI InChI=1S/C18H14N2O2/c21-18-11-15-6-2-1-5-14(15)10-16(18)17(20-22)8-7-13-4-3-9-19-12-13/h1-12,21-22H/b8-7+,20-17+	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.46E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Technology Sydney Curated by ChEMBL					Assay Description Inhibition of mushroom tyrosinase assessed as reduction in L-DOPA oxidase activity using L-DOPA substrate at 5 uM by Dixon plot				Bioorg Med Chem Lett 25: 4085-91 (2015) Article DOI: 10.1016/j.bmcl.2015.08.033 BindingDB Entry DOI: 10.7270/Q2P270ZQ
					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50121843 (CHEMBL3617128) Show SMILES O\N=C(/C=C/c1ccncc1)\c1cc2ccccc2cc1O Show InChI InChI=1S/C18H14N2O2/c21-18-12-15-4-2-1-3-14(15)11-16(18)17(20-22)6-5-13-7-9-19-10-8-13/h1-12,21-22H/b6-5+,20-17+	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.82E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Technology Sydney Curated by ChEMBL					Assay Description Inhibition of mushroom tyrosinase assessed as reduction in L-DOPA oxidase activity using L-DOPA substrate at 5 uM by Dixon plot				Bioorg Med Chem Lett 25: 4085-91 (2015) Article DOI: 10.1016/j.bmcl.2015.08.033 BindingDB Entry DOI: 10.7270/Q2P270ZQ
					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50066274 (CHEMBL3401549) Show SMILES OC(\C=C\c1ccncc1)c1ccccc1O Show InChI InChI=1S/C14H13NO2/c16-13-4-2-1-3-12(13)14(17)6-5-11-7-9-15-10-8-11/h1-10,14,16-17H/b6-5+	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Technology Sydney Curated by ChEMBL					Assay Description Competitive inhibition of mushroom tyrosinase assessed as inhibition of L-DOPA oxidase activity at 5 uM active compound by Lineweaver-Burk plot analy...				Bioorg Med Chem Lett 25: 1753-6 (2015) Article DOI: 10.1016/j.bmcl.2015.02.060 BindingDB Entry DOI: 10.7270/Q2T72K42
					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50133897 (CHEMBL3634267) Show SMILES Oc1ccc(\C=C2\Cc3ccccc3C2=O)cc1O Show InChI InChI=1S/C16H12O3/c17-14-6-5-10(8-15(14)18)7-12-9-11-3-1-2-4-13(11)16(12)19/h1-8,17-18H,9H2/b12-7-	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Technology Sydney Curated by ChEMBL					Assay Description Competitive inhibition of mushroom tyrosinase polyphenol oxidase activity using L-DOPA as substrate by Dixon plot analysis				Bioorg Med Chem Lett 25: 5495-9 (2015) Article DOI: 10.1016/j.bmcl.2015.10.071 BindingDB Entry DOI: 10.7270/Q2N018C4
					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50031467 (5-HYDROXY-2-(HYDROXYMETHYL)-4H-PYRAN-4-ONE | 5-Hyd...) Show SMILES OCc1cc(=O)c(O)co1 Show InChI InChI=1S/C6H6O4/c7-2-4-1-5(8)6(9)3-10-4/h1,3,7,9H,2H2	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	8.89E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Technology Sydney Curated by ChEMBL					Assay Description Competitive inhibition of mushroom tyrosinase assessed as inhibition of L-DOPA oxidase activity at 5 uM active compound by Lineweaver-Burk plot analy...				Bioorg Med Chem Lett 25: 1753-6 (2015) Article DOI: 10.1016/j.bmcl.2015.02.060 BindingDB Entry DOI: 10.7270/Q2T72K42
					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50121845 (CHEMBL3617130) Show SMILES COc1ccc(OC)c(\C=C\C(=N/O)\c2cc3ccccc3cc2O)c1 Show InChI InChI=1S/C21H19NO4/c1-25-17-8-10-21(26-2)16(11-17)7-9-19(22-24)18-12-14-5-3-4-6-15(14)13-20(18)23/h3-13,23-24H,1-2H3/b9-7+,22-19+	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Technology Sydney Curated by ChEMBL					Assay Description Inhibition of mushroom tyrosinase assessed as reduction in L-DOPA oxidase activity using L-DOPA substrate at 5 uM by Dixon plot				Bioorg Med Chem Lett 25: 4085-91 (2015) Article DOI: 10.1016/j.bmcl.2015.08.033 BindingDB Entry DOI: 10.7270/Q2P270ZQ
					More data for this Ligand-Target Pair
Membrane primary amine oxidase (Rattus norvegicus (Rat))	BDBM16173 (3,5-diamino-6-chloro-N-(diaminomethylene)pyrazinam...) Show SMILES NC(=N)NC(=O)c1nc(Cl)c(N)nc1N Show InChI InChI=1S/C6H8ClN7O/c7-2-4(9)13-3(8)1(12-2)5(15)14-6(10)11/h(H4,8,9,13)(H4,10,11,14,15)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Technology Curated by ChEMBL					Assay Description Inhibitory activity of the compound against porcine kidney amine oxidase				Bioorg Med Chem Lett 11: 2565-8 (2001) BindingDB Entry DOI: 10.7270/Q25T3JR2
					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50133898 (CHEMBL3634266) Show SMILES Oc1ccc(\C=C2\Cc3ccccc3C2=O)c(O)c1 Show InChI InChI=1S/C16H12O3/c17-13-6-5-11(15(18)9-13)8-12-7-10-3-1-2-4-14(10)16(12)19/h1-6,8-9,17-18H,7H2/b12-8-	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.03E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Technology Sydney Curated by ChEMBL					Assay Description Competitive inhibition of mushroom tyrosinase polyphenol oxidase activity using L-DOPA as substrate by Dixon plot analysis				Bioorg Med Chem Lett 25: 5495-9 (2015) Article DOI: 10.1016/j.bmcl.2015.10.071 BindingDB Entry DOI: 10.7270/Q2N018C4
					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50121844 (CHEMBL3617129) Show SMILES COc1ccc(\C=C\C(=N/O)\c2cc3ccccc3cc2O)c(OC)c1 Show InChI InChI=1S/C21H19NO4/c1-25-17-9-7-14(21(13-17)26-2)8-10-19(22-24)18-11-15-5-3-4-6-16(15)12-20(18)23/h3-13,23-24H,1-2H3/b10-8+,22-19+	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.06E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Technology Sydney Curated by ChEMBL					Assay Description Inhibition of mushroom tyrosinase assessed as reduction in L-DOPA oxidase activity using L-DOPA substrate at 5 uM by Dixon plot				Bioorg Med Chem Lett 25: 4085-91 (2015) Article DOI: 10.1016/j.bmcl.2015.08.033 BindingDB Entry DOI: 10.7270/Q2P270ZQ
					More data for this Ligand-Target Pair
Polyphenol oxidase 1 [N65D,S176D,K211T,P277A,P406L] (Agaricus bisporus (Mushroom))	BDBM173583 ((2E)-3-(2,5-dihydroxyphenyl)-1-(3-hydroxynaphthale...) Show SMILES Oc1ccc(O)c(\C=C\C(=O)c2cc3ccccc3cc2O)c1 Show InChI InChI=1S/C19H14O4/c20-15-6-8-17(21)14(9-15)5-7-18(22)16-10-12-3-1-2-4-13(12)11-19(16)23/h1-11,20-21,23H/b7-5+	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	1.08E+4	n/a	2.04E+4	n/a	n/a	n/a	n/a	6.8	n/a
University of Technology Sydney					Assay Description The mushroom tyrosinase inhibition activity of hydroxy naphthylchalcone compounds was measured using L-DOPA as substrate. The activity assay used 3 m...				Bioorg Chem 63: 116-22 (2015) Article DOI: 10.1016/j.bioorg.2015.10.003 BindingDB Entry DOI: 10.7270/Q2MS3RH3
					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50121848 (CHEMBL3617038) Show SMILES O\N=C(/C=C/c1ccccn1)\c1cc2ccccc2cc1O Show InChI InChI=1S/C18H14N2O2/c21-18-12-14-6-2-1-5-13(14)11-16(18)17(20-22)9-8-15-7-3-4-10-19-15/h1-12,21-22H/b9-8+,20-17+	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.11E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Technology Sydney Curated by ChEMBL					Assay Description Inhibition of mushroom tyrosinase assessed as reduction in L-DOPA oxidase activity using L-DOPA substrate at 5 uM by Dixon plot				Bioorg Med Chem Lett 25: 4085-91 (2015) Article DOI: 10.1016/j.bmcl.2015.08.033 BindingDB Entry DOI: 10.7270/Q2P270ZQ
					More data for this Ligand-Target Pair
Polyphenol oxidase 1 [N65D,S176D,K211T,P277A,P406L] (Agaricus bisporus (Mushroom))	BDBM173585 ((2E)-1-(3-hydroxynaphthalen-2-yl)-3-(2-hydroxy-4-n...) Show SMILES Oc1cc(ccc1\C=C\C(=O)c1cc2ccccc2cc1O)[N+]([O-])=O Show InChI InChI=1S/C19H13NO5/c21-17(8-6-12-5-7-15(20(24)25)11-18(12)22)16-9-13-3-1-2-4-14(13)10-19(16)23/h1-11,22-23H/b8-6+	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.12E+4	n/a	2.29E+4	n/a	n/a	n/a	n/a	6.8	n/a
University of Technology Sydney					Assay Description The mushroom tyrosinase inhibition activity of hydroxy naphthylchalcone compounds was measured using L-DOPA as substrate. The activity assay used 3 m...				Bioorg Chem 63: 116-22 (2015) Article DOI: 10.1016/j.bioorg.2015.10.003 BindingDB Entry DOI: 10.7270/Q2MS3RH3
					More data for this Ligand-Target Pair
Polyphenol oxidase 1 [N65D,S176D,K211T,P277A,P406L] (Agaricus bisporus (Mushroom))	BDBM173586 ((2E)-1-(3-hydroxynaphthalen-2-yl)-3-(4-hydroxy-3-n...) Show SMILES Oc1ccc(\C=C\C(=O)c2cc3ccccc3cc2O)cc1[N+]([O-])=O Show InChI InChI=1S/C19H13NO5/c21-17(7-5-12-6-8-18(22)16(9-12)20(24)25)15-10-13-3-1-2-4-14(13)11-19(15)23/h1-11,22-23H/b7-5+	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	1.19E+4	n/a	2.56E+4	n/a	n/a	n/a	n/a	6.8	n/a
University of Technology Sydney					Assay Description The mushroom tyrosinase inhibition activity of hydroxy naphthylchalcone compounds was measured using L-DOPA as substrate. The activity assay used 3 m...				Bioorg Chem 63: 116-22 (2015) Article DOI: 10.1016/j.bioorg.2015.10.003 BindingDB Entry DOI: 10.7270/Q2MS3RH3
					More data for this Ligand-Target Pair
Polyphenol oxidase 1 [N65D,S176D,K211T,P277A,P406L] (Agaricus bisporus (Mushroom))	BDBM50031467 (5-HYDROXY-2-(HYDROXYMETHYL)-4H-PYRAN-4-ONE | 5-Hyd...) Show SMILES OCc1cc(=O)c(O)co1 Show InChI InChI=1S/C6H6O4/c7-2-4-1-5(8)6(9)3-10-4/h1,3,7,9H,2H2	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	1.22E+4	n/a	2.75E+4	n/a	n/a	n/a	n/a	6.8	n/a
University of Technology Sydney					Assay Description The mushroom tyrosinase inhibition activity of hydroxy naphthylchalcone compounds was measured using L-DOPA as substrate. The activity assay used 3 m...				Bioorg Chem 63: 116-22 (2015) Article DOI: 10.1016/j.bioorg.2015.10.003 BindingDB Entry DOI: 10.7270/Q2MS3RH3
					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50031467 (5-HYDROXY-2-(HYDROXYMETHYL)-4H-PYRAN-4-ONE | 5-Hyd...) Show SMILES OCc1cc(=O)c(O)co1 Show InChI InChI=1S/C6H6O4/c7-2-4-1-5(8)6(9)3-10-4/h1,3,7,9H,2H2	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	1.22E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Technology Sydney Curated by ChEMBL					Assay Description Competitive inhibition of mushroom tyrosinase polyphenol oxidase activity using L-DOPA as substrate by Dixon plot analysis				Bioorg Med Chem Lett 25: 5495-9 (2015) Article DOI: 10.1016/j.bmcl.2015.10.071 BindingDB Entry DOI: 10.7270/Q2N018C4
					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50121846 (CHEMBL3617131) Show SMILES COc1ccc(\C=C\C(=N/O)\c2cc3ccccc3cc2O)cc1OC Show InChI InChI=1S/C21H19NO4/c1-25-20-10-8-14(11-21(20)26-2)7-9-18(22-24)17-12-15-5-3-4-6-16(15)13-19(17)23/h3-13,23-24H,1-2H3/b9-7+,22-18+	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.30E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Technology Sydney Curated by ChEMBL					Assay Description Inhibition of mushroom tyrosinase assessed as reduction in L-DOPA oxidase activity using L-DOPA substrate at 5 uM by Dixon plot				Bioorg Med Chem Lett 25: 4085-91 (2015) Article DOI: 10.1016/j.bmcl.2015.08.033 BindingDB Entry DOI: 10.7270/Q2P270ZQ
					More data for this Ligand-Target Pair
Membrane primary amine oxidase (Rattus norvegicus (Rat))	BDBM50104435 (4-(6-Guanidino-hexanoyloxy)-benzoic acid ethyl est...) Show SMILES CCOC(=O)c1ccc(OC(=O)CCCCCNC(N)=N)cc1 Show InChI InChI=1S/C16H23N3O4/c1-2-22-15(21)12-7-9-13(10-8-12)23-14(20)6-4-3-5-11-19-16(17)18/h7-10H,2-6,11H2,1H3,(H4,17,18,19)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents	PubMed	2.70E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Technology Curated by ChEMBL					Assay Description Inhibitory activity of the compound against porcine kidney amine oxidase				Bioorg Med Chem Lett 11: 2565-8 (2001) BindingDB Entry DOI: 10.7270/Q25T3JR2
					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50121847 (CHEMBL3617132) Show SMILES COc1cc(OC)cc(\C=C\C(=N/O)\c2cc3ccccc3cc2O)c1 Show InChI InChI=1S/C21H19NO4/c1-25-17-9-14(10-18(13-17)26-2)7-8-20(22-24)19-11-15-5-3-4-6-16(15)12-21(19)23/h3-13,23-24H,1-2H3/b8-7+,22-20+	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.86E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Technology Sydney Curated by ChEMBL					Assay Description Inhibition of mushroom tyrosinase assessed as reduction in L-DOPA oxidase activity using L-DOPA substrate at 5 uM by Dixon plot				Bioorg Med Chem Lett 25: 4085-91 (2015) Article DOI: 10.1016/j.bmcl.2015.08.033 BindingDB Entry DOI: 10.7270/Q2P270ZQ
					More data for this Ligand-Target Pair
Membrane primary amine oxidase (Rattus norvegicus (Rat))	BDBM50016897 (2-(2,6-dichloroanilino)-1,3-diazacyclopentene-(2) ...) Show SMILES Clc1cccc(Cl)c1\[#7]=[#6]-1\[#7]-[#6]-[#6]-[#7]-1 Show InChI InChI=1S/C9H9Cl2N3/c10-6-2-1-3-7(11)8(6)14-9-12-4-5-13-9/h1-3H,4-5H2,(H2,12,13,14)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid PDB UniChem Patents Similars	PubMed	9.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Technology Curated by ChEMBL					Assay Description Inhibitory activity of the compound against porcine kidney amine oxidase				Bioorg Med Chem Lett 11: 2565-8 (2001) BindingDB Entry DOI: 10.7270/Q25T3JR2
					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50066275 (CHEMBL3401548) Show SMILES OC(\C=C\c1ccccn1)c1ccccc1O Show InChI InChI=1S/C14H13NO2/c16-13-7-2-1-6-12(13)14(17)9-8-11-5-3-4-10-15-11/h1-10,14,16-17H/b9-8+	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Technology Sydney Curated by ChEMBL					Assay Description Competitive inhibition of mushroom tyrosinase assessed as inhibition of L-DOPA oxidase activity				Bioorg Med Chem Lett 25: 1753-6 (2015) Article DOI: 10.1016/j.bmcl.2015.02.060 BindingDB Entry DOI: 10.7270/Q2T72K42
					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50066274 (CHEMBL3401549) Show SMILES OC(\C=C\c1ccncc1)c1ccccc1O Show InChI InChI=1S/C14H13NO2/c16-13-4-2-1-3-12(13)14(17)6-5-11-7-9-15-10-8-11/h1-10,14,16-17H/b6-5+	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Technology Sydney Curated by ChEMBL					Assay Description Competitive inhibition of mushroom tyrosinase assessed as inhibition of L-DOPA oxidase activity				Bioorg Med Chem Lett 25: 1753-6 (2015) Article DOI: 10.1016/j.bmcl.2015.02.060 BindingDB Entry DOI: 10.7270/Q2T72K42
					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50133897 (CHEMBL3634267) Show SMILES Oc1ccc(\C=C2\Cc3ccccc3C2=O)cc1O Show InChI InChI=1S/C16H12O3/c17-14-6-5-10(8-15(14)18)7-12-9-11-3-1-2-4-13(11)16(12)19/h1-8,17-18H,9H2/b12-7-	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Technology Sydney Curated by ChEMBL					Assay Description Inhibition of mushroom tyrosinase diphenolase activity using L-DOPA as substrate				Bioorg Med Chem Lett 25: 5495-9 (2015) Article DOI: 10.1016/j.bmcl.2015.10.071 BindingDB Entry DOI: 10.7270/Q2N018C4
					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50031467 (5-HYDROXY-2-(HYDROXYMETHYL)-4H-PYRAN-4-ONE | 5-Hyd...) Show SMILES OCc1cc(=O)c(O)co1 Show InChI InChI=1S/C6H6O4/c7-2-4-1-5(8)6(9)3-10-4/h1,3,7,9H,2H2	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	1.12E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Technology Sydney Curated by ChEMBL					Assay Description Inhibition of mushroom tyrosinase assessed as reduction in L-DOPA oxidase activity using L-DOPA substrate at 5 uM by Dixon plot				Bioorg Med Chem Lett 25: 4085-91 (2015) Article DOI: 10.1016/j.bmcl.2015.08.033 BindingDB Entry DOI: 10.7270/Q2P270ZQ
					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50121842 (CHEMBL3617039) Show SMILES O\N=C(/C=C/c1cccnc1)\c1cc2ccccc2cc1O Show InChI InChI=1S/C18H14N2O2/c21-18-11-15-6-2-1-5-14(15)10-16(18)17(20-22)8-7-13-4-3-9-19-12-13/h1-12,21-22H/b8-7+,20-17+	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.22E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Technology Sydney Curated by ChEMBL					Assay Description Inhibition of mushroom tyrosinase assessed as reduction in L-DOPA oxidase activity using L-DOPA substrate				Bioorg Med Chem Lett 25: 4085-91 (2015) Article DOI: 10.1016/j.bmcl.2015.08.033 BindingDB Entry DOI: 10.7270/Q2P270ZQ
					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50133898 (CHEMBL3634266) Show SMILES Oc1ccc(\C=C2\Cc3ccccc3C2=O)c(O)c1 Show InChI InChI=1S/C16H12O3/c17-13-6-5-11(15(18)9-13)8-12-7-10-3-1-2-4-14(10)16(12)19/h1-6,8-9,17-18H,7H2/b12-8-	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.23E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Technology Sydney Curated by ChEMBL					Assay Description Inhibition of mushroom tyrosinase diphenolase activity using L-DOPA as substrate				Bioorg Med Chem Lett 25: 5495-9 (2015) Article DOI: 10.1016/j.bmcl.2015.10.071 BindingDB Entry DOI: 10.7270/Q2N018C4
					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50121843 (CHEMBL3617128) Show SMILES O\N=C(/C=C/c1ccncc1)\c1cc2ccccc2cc1O Show InChI InChI=1S/C18H14N2O2/c21-18-12-15-4-2-1-3-14(15)11-16(18)17(20-22)6-5-13-7-9-19-10-8-13/h1-12,21-22H/b6-5+,20-17+	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.95E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Technology Sydney Curated by ChEMBL					Assay Description Inhibition of mushroom tyrosinase assessed as reduction in L-DOPA oxidase activity using L-DOPA substrate				Bioorg Med Chem Lett 25: 4085-91 (2015) Article DOI: 10.1016/j.bmcl.2015.08.033 BindingDB Entry DOI: 10.7270/Q2P270ZQ
					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50121848 (CHEMBL3617038) Show SMILES O\N=C(/C=C/c1ccccn1)\c1cc2ccccc2cc1O Show InChI InChI=1S/C18H14N2O2/c21-18-12-14-6-2-1-5-13(14)11-16(18)17(20-22)9-8-15-7-3-4-10-19-15/h1-12,21-22H/b9-8+,20-17+	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.03E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Technology Sydney Curated by ChEMBL					Assay Description Inhibition of mushroom tyrosinase assessed as reduction in L-DOPA oxidase activity using L-DOPA substrate				Bioorg Med Chem Lett 25: 4085-91 (2015) Article DOI: 10.1016/j.bmcl.2015.08.033 BindingDB Entry DOI: 10.7270/Q2P270ZQ
					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50121845 (CHEMBL3617130) Show SMILES COc1ccc(OC)c(\C=C\C(=N/O)\c2cc3ccccc3cc2O)c1 Show InChI InChI=1S/C21H19NO4/c1-25-17-8-10-21(26-2)16(11-17)7-9-19(22-24)18-12-14-5-3-4-6-15(14)13-20(18)23/h3-13,23-24H,1-2H3/b9-7+,22-19+	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.19E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Technology Sydney Curated by ChEMBL					Assay Description Inhibition of mushroom tyrosinase assessed as reduction in L-DOPA oxidase activity using L-DOPA substrate				Bioorg Med Chem Lett 25: 4085-91 (2015) Article DOI: 10.1016/j.bmcl.2015.08.033 BindingDB Entry DOI: 10.7270/Q2P270ZQ
					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50121844 (CHEMBL3617129) Show SMILES COc1ccc(\C=C\C(=N/O)\c2cc3ccccc3cc2O)c(OC)c1 Show InChI InChI=1S/C21H19NO4/c1-25-17-9-7-14(21(13-17)26-2)8-10-19(22-24)18-11-15-5-3-4-6-16(15)12-20(18)23/h3-13,23-24H,1-2H3/b10-8+,22-19+	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Technology Sydney Curated by ChEMBL					Assay Description Inhibition of mushroom tyrosinase assessed as reduction in L-DOPA oxidase activity using L-DOPA substrate				Bioorg Med Chem Lett 25: 4085-91 (2015) Article DOI: 10.1016/j.bmcl.2015.08.033 BindingDB Entry DOI: 10.7270/Q2P270ZQ
					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50031467 (5-HYDROXY-2-(HYDROXYMETHYL)-4H-PYRAN-4-ONE | 5-Hyd...) Show SMILES OCc1cc(=O)c(O)co1 Show InChI InChI=1S/C6H6O4/c7-2-4-1-5(8)6(9)3-10-4/h1,3,7,9H,2H2	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	2.37E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Technology Sydney Curated by ChEMBL					Assay Description Inhibition of mushroom tyrosinase assessed as reduction in L-DOPA oxidase activity using L-DOPA substrate				Bioorg Med Chem Lett 25: 4085-91 (2015) Article DOI: 10.1016/j.bmcl.2015.08.033 BindingDB Entry DOI: 10.7270/Q2P270ZQ
					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50031467 (5-HYDROXY-2-(HYDROXYMETHYL)-4H-PYRAN-4-ONE | 5-Hyd...) Show SMILES OCc1cc(=O)c(O)co1 Show InChI InChI=1S/C6H6O4/c7-2-4-1-5(8)6(9)3-10-4/h1,3,7,9H,2H2	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	2.73E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Technology Sydney Curated by ChEMBL					Assay Description Competitive inhibition of mushroom tyrosinase assessed as inhibition of L-DOPA oxidase activity				Bioorg Med Chem Lett 25: 1753-6 (2015) Article DOI: 10.1016/j.bmcl.2015.02.060 BindingDB Entry DOI: 10.7270/Q2T72K42
					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50031467 (5-HYDROXY-2-(HYDROXYMETHYL)-4H-PYRAN-4-ONE | 5-Hyd...) Show SMILES OCc1cc(=O)c(O)co1 Show InChI InChI=1S/C6H6O4/c7-2-4-1-5(8)6(9)3-10-4/h1,3,7,9H,2H2	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	2.75E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Technology Sydney Curated by ChEMBL					Assay Description Inhibition of mushroom tyrosinase diphenolase activity using L-DOPA as substrate				Bioorg Med Chem Lett 25: 5495-9 (2015) Article DOI: 10.1016/j.bmcl.2015.10.071 BindingDB Entry DOI: 10.7270/Q2N018C4
					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50121846 (CHEMBL3617131) Show SMILES COc1ccc(\C=C\C(=N/O)\c2cc3ccccc3cc2O)cc1OC Show InChI InChI=1S/C21H19NO4/c1-25-20-10-8-14(11-21(20)26-2)7-9-18(22-24)17-12-15-5-3-4-6-16(15)13-19(17)23/h3-13,23-24H,1-2H3/b9-7+,22-18+	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.23E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Technology Sydney Curated by ChEMBL					Assay Description Inhibition of mushroom tyrosinase assessed as reduction in L-DOPA oxidase activity using L-DOPA substrate				Bioorg Med Chem Lett 25: 4085-91 (2015) Article DOI: 10.1016/j.bmcl.2015.08.033 BindingDB Entry DOI: 10.7270/Q2P270ZQ
					More data for this Ligand-Target Pair
Polyphenol oxidase 2 (Agaricus bisporus (Common mushroom))	BDBM50121847 (CHEMBL3617132) Show SMILES COc1cc(OC)cc(\C=C\C(=N/O)\c2cc3ccccc3cc2O)c1 Show InChI InChI=1S/C21H19NO4/c1-25-17-9-14(10-18(13-17)26-2)7-8-20(22-24)19-11-15-5-3-4-6-16(15)12-21(19)23/h3-13,23-24H,1-2H3/b8-7+,22-20+	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.29E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Technology Sydney Curated by ChEMBL					Assay Description Inhibition of mushroom tyrosinase assessed as reduction in L-DOPA oxidase activity using L-DOPA substrate				Bioorg Med Chem Lett 25: 4085-91 (2015) Article DOI: 10.1016/j.bmcl.2015.08.033 BindingDB Entry DOI: 10.7270/Q2P270ZQ
					More data for this Ligand-Target Pair