Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Fatty-acid amide hydrolase 1 (Homo sapiens (Human)) | BDBM50250852 (CHEMBL4078217) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.160 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of human recombinant FAAH using arachidonoyl-AMC as substrate preincubated for 30 mins followed by substrate addition measured after 60 mi... | J Med Chem 60: 9860-9873 (2017) Article DOI: 10.1021/acs.jmedchem.7b01531 BindingDB Entry DOI: 10.7270/Q2N300CG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monoglyceride lipase (Homo sapiens (Human)) | BDBM50250848 (CHEMBL4059676) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.180 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of MAGL in human brain vascular pericytes after 1 hr by TAMRA azide-based In-gel fluorescence method | J Med Chem 60: 9860-9873 (2017) Article DOI: 10.1021/acs.jmedchem.7b01531 BindingDB Entry DOI: 10.7270/Q2N300CG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monoglyceride lipase (Homo sapiens (Human)) | BDBM50250859 (CHEMBL4097203) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.180 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of MAGL in human brain vascular pericytes after 1 hr by TAMRA azide-based In-gel fluorescence method | J Med Chem 60: 9860-9873 (2017) Article DOI: 10.1021/acs.jmedchem.7b01531 BindingDB Entry DOI: 10.7270/Q2N300CG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monoglyceride lipase (Homo sapiens (Human)) | BDBM50250855 (CHEMBL4077745) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.300 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of MAGL in human brain vascular pericytes after 1 hr by TAMRA azide-based In-gel fluorescence method | J Med Chem 60: 9860-9873 (2017) Article DOI: 10.1021/acs.jmedchem.7b01531 BindingDB Entry DOI: 10.7270/Q2N300CG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monoglyceride lipase (Homo sapiens (Human)) | BDBM50250850 (CHEMBL4089505) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | 0.380 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of MAGL in human brain vascular pericytes after 1 hr by TAMRA azide-based In-gel fluorescence method | J Med Chem 60: 9860-9873 (2017) Article DOI: 10.1021/acs.jmedchem.7b01531 BindingDB Entry DOI: 10.7270/Q2N300CG | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Monoglyceride lipase (Homo sapiens (Human)) | BDBM50250852 (CHEMBL4078217) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.410 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of MAGL in human brain vascular pericytes after 1 hr by TAMRA azide-based In-gel fluorescence method | J Med Chem 60: 9860-9873 (2017) Article DOI: 10.1021/acs.jmedchem.7b01531 BindingDB Entry DOI: 10.7270/Q2N300CG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fatty-acid amide hydrolase 1 (Homo sapiens (Human)) | BDBM50250855 (CHEMBL4077745) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.490 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of human recombinant FAAH using arachidonoyl-AMC as substrate preincubated for 30 mins followed by substrate addition measured after 60 mi... | J Med Chem 60: 9860-9873 (2017) Article DOI: 10.1021/acs.jmedchem.7b01531 BindingDB Entry DOI: 10.7270/Q2N300CG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fatty-acid amide hydrolase 1 (Homo sapiens (Human)) | BDBM50250859 (CHEMBL4097203) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.670 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of human recombinant FAAH using arachidonoyl-AMC as substrate preincubated for 30 mins followed by substrate addition measured after 60 mi... | J Med Chem 60: 9860-9873 (2017) Article DOI: 10.1021/acs.jmedchem.7b01531 BindingDB Entry DOI: 10.7270/Q2N300CG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monoglyceride lipase (Homo sapiens (Human)) | BDBM50250854 (CHEMBL4079190) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.740 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of MAGL in human brain vascular pericytes after 1 hr by TAMRA azide-based In-gel fluorescence method | J Med Chem 60: 9860-9873 (2017) Article DOI: 10.1021/acs.jmedchem.7b01531 BindingDB Entry DOI: 10.7270/Q2N300CG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fatty-acid amide hydrolase 1 (Homo sapiens (Human)) | BDBM50250854 (CHEMBL4079190) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.10 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of human recombinant FAAH using arachidonoyl-AMC as substrate preincubated for 30 mins followed by substrate addition measured after 60 mi... | J Med Chem 60: 9860-9873 (2017) Article DOI: 10.1021/acs.jmedchem.7b01531 BindingDB Entry DOI: 10.7270/Q2N300CG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monoglyceride lipase (Homo sapiens (Human)) | BDBM50250853 (CHEMBL4102496) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.90 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of MAGL in human brain vascular pericytes after 1 hr by TAMRA azide-based In-gel fluorescence method | J Med Chem 60: 9860-9873 (2017) Article DOI: 10.1021/acs.jmedchem.7b01531 BindingDB Entry DOI: 10.7270/Q2N300CG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monoglyceride lipase (Homo sapiens (Human)) | BDBM50250849 (CHEMBL4068332) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.90 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of MAGL in human brain vascular pericytes after 1 hr by TAMRA azide-based In-gel fluorescence method | J Med Chem 60: 9860-9873 (2017) Article DOI: 10.1021/acs.jmedchem.7b01531 BindingDB Entry DOI: 10.7270/Q2N300CG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monoglyceride lipase (Homo sapiens (Human)) | BDBM50250851 (CHEMBL4096459) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of MAGL in human brain vascular pericytes after 1 hr by TAMRA azide-based In-gel fluorescence method | J Med Chem 60: 9860-9873 (2017) Article DOI: 10.1021/acs.jmedchem.7b01531 BindingDB Entry DOI: 10.7270/Q2N300CG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monoglyceride lipase (Homo sapiens (Human)) | BDBM50250858 (CHEMBL4078417) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of MAGL in human brain vascular pericytes after 1 hr by TAMRA azide-based In-gel fluorescence method | J Med Chem 60: 9860-9873 (2017) Article DOI: 10.1021/acs.jmedchem.7b01531 BindingDB Entry DOI: 10.7270/Q2N300CG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monoglyceride lipase (Homo sapiens (Human)) | BDBM50250857 (CHEMBL4081625) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.20 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of MAGL in human brain vascular pericytes after 1 hr by TAMRA azide-based In-gel fluorescence method | J Med Chem 60: 9860-9873 (2017) Article DOI: 10.1021/acs.jmedchem.7b01531 BindingDB Entry DOI: 10.7270/Q2N300CG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fatty-acid amide hydrolase 1 (Homo sapiens (Human)) | BDBM50250853 (CHEMBL4102496) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 9.40 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of human recombinant FAAH using arachidonoyl-AMC as substrate preincubated for 30 mins followed by substrate addition measured after 60 mi... | J Med Chem 60: 9860-9873 (2017) Article DOI: 10.1021/acs.jmedchem.7b01531 BindingDB Entry DOI: 10.7270/Q2N300CG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fatty-acid amide hydrolase 1 (Homo sapiens (Human)) | BDBM50250856 (CHEMBL4104911) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | >20 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of human recombinant FAAH using arachidonoyl-AMC as substrate preincubated for 30 mins followed by substrate addition measured after 60 mi... | J Med Chem 60: 9860-9873 (2017) Article DOI: 10.1021/acs.jmedchem.7b01531 BindingDB Entry DOI: 10.7270/Q2N300CG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monoglyceride lipase (Homo sapiens (Human)) | BDBM50250856 (CHEMBL4104911) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 39 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of MAGL in human brain vascular pericytes after 1 hr by TAMRA azide-based In-gel fluorescence method | J Med Chem 60: 9860-9873 (2017) Article DOI: 10.1021/acs.jmedchem.7b01531 BindingDB Entry DOI: 10.7270/Q2N300CG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclic GMP-AMP synthase (Homo sapiens) | BDBM17051 (BX-795 | BX-795, 3 | N-(3-{[5-iodo-4-({3-[(thiophe...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 60 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of cGAS in human THP1 cells assessed as reduction in salmon sperm dsDNA-induced IFN-beta expression preincubated for 1 hr followed by dsDN... | PLoS ONE 12: (2017) Article DOI: 10.1371/journal.pone.0184843 BindingDB Entry DOI: 10.7270/Q2WQ067J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fatty-acid amide hydrolase 1 (Homo sapiens (Human)) | BDBM50250848 (CHEMBL4059676) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 260 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of human recombinant FAAH using arachidonoyl-AMC as substrate preincubated for 30 mins followed by substrate addition measured after 60 mi... | J Med Chem 60: 9860-9873 (2017) Article DOI: 10.1021/acs.jmedchem.7b01531 BindingDB Entry DOI: 10.7270/Q2N300CG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fatty-acid amide hydrolase 1 (Homo sapiens (Human)) | BDBM50250850 (CHEMBL4089505) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 420 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of human recombinant FAAH using arachidonoyl-AMC as substrate preincubated for 30 mins followed by substrate addition measured after 60 mi... | J Med Chem 60: 9860-9873 (2017) Article DOI: 10.1021/acs.jmedchem.7b01531 BindingDB Entry DOI: 10.7270/Q2N300CG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclic GMP-AMP synthase (Homo sapiens) | BDBM50250108 (CHEMBL4096573) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of human cGAS (2 to 522 residues) expressed in Sf9 insect cells assessed as reduction in cGAMP level using ISD DNA as substrate in presenc... | PLoS ONE 12: (2017) Article DOI: 10.1371/journal.pone.0184843 BindingDB Entry DOI: 10.7270/Q2WQ067J | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Fatty-acid amide hydrolase 1 (Homo sapiens (Human)) | BDBM50250857 (CHEMBL4081625) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of human recombinant FAAH using arachidonoyl-AMC as substrate preincubated for 30 mins followed by substrate addition measured after 60 mi... | J Med Chem 60: 9860-9873 (2017) Article DOI: 10.1021/acs.jmedchem.7b01531 BindingDB Entry DOI: 10.7270/Q2N300CG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclic GMP-AMP synthase (Homo sapiens) | BDBM50250108 (CHEMBL4096573) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | 4.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of human cGAS (2 to 522 residues) expressed in Sf9 insect cells assessed as reduction in cGAMP level using ISD DNA as substrate in presenc... | PLoS ONE 12: (2017) Article DOI: 10.1371/journal.pone.0184843 BindingDB Entry DOI: 10.7270/Q2WQ067J | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Cyclic GMP-AMP synthase (Homo sapiens) | BDBM50250111 (CHEMBL4084664) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | 8.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of human cGAS (2 to 522 residues) expressed in Sf9 insect cells assessed as reduction in cGAMP level using ISD DNA as substrate in presenc... | PLoS ONE 12: (2017) Article DOI: 10.1371/journal.pone.0184843 BindingDB Entry DOI: 10.7270/Q2WQ067J | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Cyclic GMP-AMP synthase (Homo sapiens) | BDBM50250109 (CHEMBL4062994) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.06E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of human cGAS (2 to 522 residues) expressed in Sf9 insect cells assessed as reduction in cGAMP level using ISD DNA as substrate in presenc... | PLoS ONE 12: (2017) Article DOI: 10.1371/journal.pone.0184843 BindingDB Entry DOI: 10.7270/Q2WQ067J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclic GMP-AMP synthase (Homo sapiens) | BDBM50250106 (CHEMBL4103560) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.51E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of human cGAS (2 to 522 residues) expressed in Sf9 insect cells assessed as reduction in cGAMP level using ISD DNA as substrate in presenc... | PLoS ONE 12: (2017) Article DOI: 10.1371/journal.pone.0184843 BindingDB Entry DOI: 10.7270/Q2WQ067J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclic GMP-AMP synthase (Homo sapiens) | BDBM50250111 (CHEMBL4084664) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | 1.75E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of human cGAS (2 to 522 residues) expressed in Sf9 insect cells assessed as reduction in cGAMP level using ISD DNA as substrate in presenc... | PLoS ONE 12: (2017) Article DOI: 10.1371/journal.pone.0184843 BindingDB Entry DOI: 10.7270/Q2WQ067J | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Cyclic GMP-AMP synthase (Homo sapiens) | BDBM50250106 (CHEMBL4103560) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 1.90E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of human cGAS (2 to 522 residues) expressed in Sf9 insect cells assessed as reduction in cGAMP level using ISD DNA as substrate in presenc... | PLoS ONE 12: (2017) Article DOI: 10.1371/journal.pone.0184843 BindingDB Entry DOI: 10.7270/Q2WQ067J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclic GMP-AMP synthase (Homo sapiens) | BDBM50250109 (CHEMBL4062994) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of human cGAS (2 to 522 residues) expressed in Sf9 insect cells assessed as reduction in cGAMP level using ISD DNA as substrate in presenc... | PLoS ONE 12: (2017) Article DOI: 10.1371/journal.pone.0184843 BindingDB Entry DOI: 10.7270/Q2WQ067J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Fatty-acid amide hydrolase 1 (Homo sapiens (Human)) | BDBM50250849 (CHEMBL4068332) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of human recombinant FAAH using arachidonoyl-AMC as substrate preincubated for 30 mins followed by substrate addition measured after 60 mi... | J Med Chem 60: 9860-9873 (2017) Article DOI: 10.1021/acs.jmedchem.7b01531 BindingDB Entry DOI: 10.7270/Q2N300CG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclic GMP-AMP synthase (Homo sapiens) | BDBM50250107 (CHEMBL4085628) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | 6.90E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of human cGAS (2 to 522 residues) expressed in Sf9 insect cells assessed as reduction in cGAMP level using ISD DNA as substrate in presenc... | PLoS ONE 12: (2017) Article DOI: 10.1371/journal.pone.0184843 BindingDB Entry DOI: 10.7270/Q2WQ067J | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Cyclic GMP-AMP synthase (Homo sapiens) | BDBM50250110 (CHEMBL4065757) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | 7.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of human cGAS (2 to 522 residues) expressed in Sf9 insect cells assessed as reduction in cGAMP level using ISD DNA as substrate in presenc... | PLoS ONE 12: (2017) Article DOI: 10.1371/journal.pone.0184843 BindingDB Entry DOI: 10.7270/Q2WQ067J | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Cyclic GMP-AMP synthase (Homo sapiens) | BDBM50250107 (CHEMBL4085628) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | 1.25E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Inhibition of human cGAS (2 to 522 residues) expressed in Sf9 insect cells assessed as reduction in cGAMP level using ISD DNA as substrate in presenc... | PLoS ONE 12: (2017) Article DOI: 10.1371/journal.pone.0184843 BindingDB Entry DOI: 10.7270/Q2WQ067J | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Cyclic GMP-AMP synthase (Homo sapiens) | BDBM50250106 (CHEMBL4103560) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | 1.25E+4 | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Binding affinity to human cGAS (2 to 522 residues) expressed in Sf9 insect cells by surface plasmon resonance assay | PLoS ONE 12: (2017) Article DOI: 10.1371/journal.pone.0184843 BindingDB Entry DOI: 10.7270/Q2WQ067J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclic GMP-AMP synthase (Homo sapiens) | BDBM50250109 (CHEMBL4062994) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | 6.70E+3 | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Binding affinity to human cGAS (2 to 522 residues) expressed in Sf9 insect cells by surface plasmon resonance assay | PLoS ONE 12: (2017) Article DOI: 10.1371/journal.pone.0184843 BindingDB Entry DOI: 10.7270/Q2WQ067J | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclic GMP-AMP synthase (Homo sapiens) | BDBM50250107 (CHEMBL4085628) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | n/a | 7.80E+4 | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Binding affinity to human cGAS (2 to 522 residues) expressed in Sf9 insect cells by surface plasmon resonance assay | PLoS ONE 12: (2017) Article DOI: 10.1371/journal.pone.0184843 BindingDB Entry DOI: 10.7270/Q2WQ067J | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Cyclic GMP-AMP synthase (Homo sapiens) | BDBM50250110 (CHEMBL4065757) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | n/a | 1.71E+5 | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Binding affinity to human cGAS (2 to 522 residues) expressed in Sf9 insect cells by surface plasmon resonance assay | PLoS ONE 12: (2017) Article DOI: 10.1371/journal.pone.0184843 BindingDB Entry DOI: 10.7270/Q2WQ067J | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Cyclic GMP-AMP synthase (Homo sapiens) | BDBM50250111 (CHEMBL4084664) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | n/a | 2.70E+3 | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Binding affinity to human cGAS (2 to 522 residues) expressed in Sf9 insect cells by surface plasmon resonance assay | PLoS ONE 12: (2017) Article DOI: 10.1371/journal.pone.0184843 BindingDB Entry DOI: 10.7270/Q2WQ067J | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Cyclic GMP-AMP synthase (Homo sapiens) | BDBM50250108 (CHEMBL4096573) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase MCE PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a |
Pfizer Inc. Curated by ChEMBL | Assay Description Binding affinity to human cGAS (2 to 522 residues) expressed in Sf9 insect cells by surface plasmon resonance assay | PLoS ONE 12: (2017) Article DOI: 10.1371/journal.pone.0184843 BindingDB Entry DOI: 10.7270/Q2WQ067J | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) |