Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sodium-dependent serotonin transporter (Homo sapiens (Human)) | BDBM50309512 (2-(2,3-dichlorophenoxy)-3-(piperidin-4-yl)pyridine...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Displacement of [3H]citalopram from human SERT expressed in HEK293 cells by scintillation proximity assay | Bioorg Med Chem Lett 20: 1114-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.023 BindingDB Entry DOI: 10.7270/Q2NS0V17 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Homo sapiens (Human)) | BDBM50309515 (2-(2,4-dichlorophenoxy)-3-(piperidin-4-yl)pyridine...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Displacement of [3H]citalopram from human SERT expressed in HEK293 cells by scintillation proximity assay | Bioorg Med Chem Lett 20: 1114-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.023 BindingDB Entry DOI: 10.7270/Q2NS0V17 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM50309523 (1-(2-(2-chloro-6-fluorophenoxy)pyridin-3-yl)pipera...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 3.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor by filtration techniques | Bioorg Med Chem Lett 20: 1114-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.023 BindingDB Entry DOI: 10.7270/Q2NS0V17 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM50309522 (1-(2-(2-chlorophenoxy)pyridin-3-yl)piperazine | CH...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 4.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor by filtration techniques | Bioorg Med Chem Lett 20: 1114-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.023 BindingDB Entry DOI: 10.7270/Q2NS0V17 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM50309505 (4-(2-fluoro-6-(2-fluorophenoxy)phenyl)piperidine |...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 4.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor by filtration techniques | Bioorg Med Chem Lett 20: 1114-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.023 BindingDB Entry DOI: 10.7270/Q2NS0V17 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM50309514 (2-(2-fluoro-4-methylphenoxy)-3-(piperidin-4-yl)pyr...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 5.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor by filtration techniques | Bioorg Med Chem Lett 20: 1114-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.023 BindingDB Entry DOI: 10.7270/Q2NS0V17 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM50309520 (2-(2,6-difluorophenoxy)-3-(piperidin-4-yl)pyridine...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 7.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor by filtration techniques | Bioorg Med Chem Lett 20: 1114-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.023 BindingDB Entry DOI: 10.7270/Q2NS0V17 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM50309521 (2-(2-fluoro-6-methylphenoxy)-3-(piperidin-4-yl)pyr...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor by filtration techniques | Bioorg Med Chem Lett 20: 1114-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.023 BindingDB Entry DOI: 10.7270/Q2NS0V17 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM50309519 (2-(2-chloro-6-fluorophenoxy)-3-(piperidin-4-yl)pyr...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 11 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor by filtration techniques | Bioorg Med Chem Lett 20: 1114-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.023 BindingDB Entry DOI: 10.7270/Q2NS0V17 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM50309507 (2-(2-fluorophenoxy)-3-(piperidin-4-yl)pyridine | C...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 13 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor by filtration techniques | Bioorg Med Chem Lett 20: 1114-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.023 BindingDB Entry DOI: 10.7270/Q2NS0V17 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM50309508 (2-(2-chlorophenoxy)-3-(piperidin-4-yl)pyridine | C...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 16 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor by filtration techniques | Bioorg Med Chem Lett 20: 1114-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.023 BindingDB Entry DOI: 10.7270/Q2NS0V17 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM50309517 (2-(2-chloro-5-fluorophenoxy)-3-(piperidin-4-yl)pyr...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 17 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor by filtration techniques | Bioorg Med Chem Lett 20: 1114-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.023 BindingDB Entry DOI: 10.7270/Q2NS0V17 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM50309518 (2-(2-fluoro-6-methoxyphenoxy)-3-(piperidin-4-yl)py...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 24 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor by filtration techniques | Bioorg Med Chem Lett 20: 1114-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.023 BindingDB Entry DOI: 10.7270/Q2NS0V17 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent noradrenaline transporter (Homo sapiens (Human)) | BDBM50309512 (2-(2,3-dichlorophenoxy)-3-(piperidin-4-yl)pyridine...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 25 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Displacement of [3H]nisoxetine from human NET expressed in HEK293 cells by scintillation proximity assay | Bioorg Med Chem Lett 20: 1114-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.023 BindingDB Entry DOI: 10.7270/Q2NS0V17 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent noradrenaline transporter (Homo sapiens (Human)) | BDBM50309521 (2-(2-fluoro-6-methylphenoxy)-3-(piperidin-4-yl)pyr...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 27 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Displacement of [3H]nisoxetine from human NET expressed in HEK293 cells by scintillation proximity assay | Bioorg Med Chem Lett 20: 1114-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.023 BindingDB Entry DOI: 10.7270/Q2NS0V17 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM50309516 (2-(2,4-difluorophenoxy)-3-(piperidin-4-yl)pyridine...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 29 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor by filtration techniques | Bioorg Med Chem Lett 20: 1114-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.023 BindingDB Entry DOI: 10.7270/Q2NS0V17 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Homo sapiens (Human)) | BDBM50309516 (2-(2,4-difluorophenoxy)-3-(piperidin-4-yl)pyridine...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Displacement of [3H]citalopram from human SERT expressed in HEK293 cells by scintillation proximity assay | Bioorg Med Chem Lett 20: 1114-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.023 BindingDB Entry DOI: 10.7270/Q2NS0V17 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent noradrenaline transporter (Homo sapiens (Human)) | BDBM50309505 (4-(2-fluoro-6-(2-fluorophenoxy)phenyl)piperidine |...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 32 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Displacement of [3H]nisoxetine from human NET expressed in HEK293 cells by scintillation proximity assay | Bioorg Med Chem Lett 20: 1114-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.023 BindingDB Entry DOI: 10.7270/Q2NS0V17 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent noradrenaline transporter (Homo sapiens (Human)) | BDBM50309519 (2-(2-chloro-6-fluorophenoxy)-3-(piperidin-4-yl)pyr...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 33 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Displacement of [3H]nisoxetine from human NET expressed in HEK293 cells by scintillation proximity assay | Bioorg Med Chem Lett 20: 1114-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.023 BindingDB Entry DOI: 10.7270/Q2NS0V17 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Homo sapiens (Human)) | BDBM50309514 (2-(2-fluoro-4-methylphenoxy)-3-(piperidin-4-yl)pyr...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 36 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Displacement of [3H]citalopram from human SERT expressed in HEK293 cells by scintillation proximity assay | Bioorg Med Chem Lett 20: 1114-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.023 BindingDB Entry DOI: 10.7270/Q2NS0V17 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM50309512 (2-(2,3-dichlorophenoxy)-3-(piperidin-4-yl)pyridine...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 37 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor by filtration techniques | Bioorg Med Chem Lett 20: 1114-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.023 BindingDB Entry DOI: 10.7270/Q2NS0V17 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM50309515 (2-(2,4-dichlorophenoxy)-3-(piperidin-4-yl)pyridine...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 37 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor by filtration techniques | Bioorg Med Chem Lett 20: 1114-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.023 BindingDB Entry DOI: 10.7270/Q2NS0V17 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Homo sapiens (Human)) | BDBM50309508 (2-(2-chlorophenoxy)-3-(piperidin-4-yl)pyridine | C...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 57 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Displacement of [3H]citalopram from human SERT expressed in HEK293 cells by scintillation proximity assay | Bioorg Med Chem Lett 20: 1114-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.023 BindingDB Entry DOI: 10.7270/Q2NS0V17 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM50309510 (3-(piperidin-4-yl)-2-(o-tolyloxy)pyridine | CHEMBL...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor by filtration techniques | Bioorg Med Chem Lett 20: 1114-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.023 BindingDB Entry DOI: 10.7270/Q2NS0V17 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM50309511 (3-(piperidin-4-yl)-2-(2-(trifluoromethyl)phenoxy)p...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 71 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor by filtration techniques | Bioorg Med Chem Lett 20: 1114-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.023 BindingDB Entry DOI: 10.7270/Q2NS0V17 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent noradrenaline transporter (Homo sapiens (Human)) | BDBM50309508 (2-(2-chlorophenoxy)-3-(piperidin-4-yl)pyridine | C...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 74 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Displacement of [3H]nisoxetine from human NET expressed in HEK293 cells by scintillation proximity assay | Bioorg Med Chem Lett 20: 1114-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.023 BindingDB Entry DOI: 10.7270/Q2NS0V17 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM50309509 (2-(2-methoxyphenoxy)-3-(piperidin-4-yl)pyridine | ...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 92 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor by filtration techniques | Bioorg Med Chem Lett 20: 1114-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.023 BindingDB Entry DOI: 10.7270/Q2NS0V17 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM50309506 (2-phenoxy-3-(piperidin-4-yl)pyridine | CHEMBL60814...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 101 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor by filtration techniques | Bioorg Med Chem Lett 20: 1114-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.023 BindingDB Entry DOI: 10.7270/Q2NS0V17 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Homo sapiens (Human)) | BDBM50309521 (2-(2-fluoro-6-methylphenoxy)-3-(piperidin-4-yl)pyr...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 102 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Displacement of [3H]citalopram from human SERT expressed in HEK293 cells by scintillation proximity assay | Bioorg Med Chem Lett 20: 1114-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.023 BindingDB Entry DOI: 10.7270/Q2NS0V17 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Homo sapiens (Human)) | BDBM50309513 (2-(2,3-difluorophenoxy)-3-(piperidin-4-yl)pyridine...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 109 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Displacement of [3H]citalopram from human SERT expressed in HEK293 cells by scintillation proximity assay | Bioorg Med Chem Lett 20: 1114-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.023 BindingDB Entry DOI: 10.7270/Q2NS0V17 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent noradrenaline transporter (Homo sapiens (Human)) | BDBM50309511 (3-(piperidin-4-yl)-2-(2-(trifluoromethyl)phenoxy)p...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 140 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Displacement of [3H]nisoxetine from human NET expressed in HEK293 cells by scintillation proximity assay | Bioorg Med Chem Lett 20: 1114-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.023 BindingDB Entry DOI: 10.7270/Q2NS0V17 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent noradrenaline transporter (Homo sapiens (Human)) | BDBM50309516 (2-(2,4-difluorophenoxy)-3-(piperidin-4-yl)pyridine...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 143 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Displacement of [3H]nisoxetine from human NET expressed in HEK293 cells by scintillation proximity assay | Bioorg Med Chem Lett 20: 1114-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.023 BindingDB Entry DOI: 10.7270/Q2NS0V17 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 1A (Homo sapiens (Human)) | BDBM50309513 (2-(2,3-difluorophenoxy)-3-(piperidin-4-yl)pyridine...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 173 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor by filtration techniques | Bioorg Med Chem Lett 20: 1114-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.023 BindingDB Entry DOI: 10.7270/Q2NS0V17 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent noradrenaline transporter (Homo sapiens (Human)) | BDBM50309520 (2-(2,6-difluorophenoxy)-3-(piperidin-4-yl)pyridine...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 181 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Displacement of [3H]nisoxetine from human NET expressed in HEK293 cells by scintillation proximity assay | Bioorg Med Chem Lett 20: 1114-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.023 BindingDB Entry DOI: 10.7270/Q2NS0V17 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Homo sapiens (Human)) | BDBM50309519 (2-(2-chloro-6-fluorophenoxy)-3-(piperidin-4-yl)pyr...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 194 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Displacement of [3H]citalopram from human SERT expressed in HEK293 cells by scintillation proximity assay | Bioorg Med Chem Lett 20: 1114-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.023 BindingDB Entry DOI: 10.7270/Q2NS0V17 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Homo sapiens (Human)) | BDBM50309511 (3-(piperidin-4-yl)-2-(2-(trifluoromethyl)phenoxy)p...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 203 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Displacement of [3H]citalopram from human SERT expressed in HEK293 cells by scintillation proximity assay | Bioorg Med Chem Lett 20: 1114-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.023 BindingDB Entry DOI: 10.7270/Q2NS0V17 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent noradrenaline transporter (Homo sapiens (Human)) | BDBM50309517 (2-(2-chloro-5-fluorophenoxy)-3-(piperidin-4-yl)pyr...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 247 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Displacement of [3H]nisoxetine from human NET expressed in HEK293 cells by scintillation proximity assay | Bioorg Med Chem Lett 20: 1114-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.023 BindingDB Entry DOI: 10.7270/Q2NS0V17 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Homo sapiens (Human)) | BDBM50309517 (2-(2-chloro-5-fluorophenoxy)-3-(piperidin-4-yl)pyr...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 251 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Displacement of [3H]citalopram from human SERT expressed in HEK293 cells by scintillation proximity assay | Bioorg Med Chem Lett 20: 1114-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.023 BindingDB Entry DOI: 10.7270/Q2NS0V17 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent noradrenaline transporter (Homo sapiens (Human)) | BDBM50309518 (2-(2-fluoro-6-methoxyphenoxy)-3-(piperidin-4-yl)py...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 276 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Displacement of [3H]nisoxetine from human NET expressed in HEK293 cells by scintillation proximity assay | Bioorg Med Chem Lett 20: 1114-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.023 BindingDB Entry DOI: 10.7270/Q2NS0V17 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent dopamine transporter (Homo sapiens (Human)) | BDBM50309505 (4-(2-fluoro-6-(2-fluorophenoxy)phenyl)piperidine |...) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 278 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Displacement of [3H]WIN35428 from human DAT expressed in HEK293 cells by scintillation proximity assay | Bioorg Med Chem Lett 20: 1114-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.023 BindingDB Entry DOI: 10.7270/Q2NS0V17 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Homo sapiens (Human)) | BDBM50309510 (3-(piperidin-4-yl)-2-(o-tolyloxy)pyridine | CHEMBL...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 292 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Displacement of [3H]citalopram from human SERT expressed in HEK293 cells by scintillation proximity assay | Bioorg Med Chem Lett 20: 1114-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.023 BindingDB Entry DOI: 10.7270/Q2NS0V17 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent noradrenaline transporter (Homo sapiens (Human)) | BDBM50309509 (2-(2-methoxyphenoxy)-3-(piperidin-4-yl)pyridine | ...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 292 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Displacement of [3H]nisoxetine from human NET expressed in HEK293 cells by scintillation proximity assay | Bioorg Med Chem Lett 20: 1114-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.023 BindingDB Entry DOI: 10.7270/Q2NS0V17 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent dopamine transporter (Homo sapiens (Human)) | BDBM50309512 (2-(2,3-dichlorophenoxy)-3-(piperidin-4-yl)pyridine...) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 310 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Displacement of [3H]WIN35428 from human DAT expressed in HEK293 cells by scintillation proximity assay | Bioorg Med Chem Lett 20: 1114-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.023 BindingDB Entry DOI: 10.7270/Q2NS0V17 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent noradrenaline transporter (Homo sapiens (Human)) | BDBM50309510 (3-(piperidin-4-yl)-2-(o-tolyloxy)pyridine | CHEMBL...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 330 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Displacement of [3H]nisoxetine from human NET expressed in HEK293 cells by scintillation proximity assay | Bioorg Med Chem Lett 20: 1114-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.023 BindingDB Entry DOI: 10.7270/Q2NS0V17 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent noradrenaline transporter (Homo sapiens (Human)) | BDBM50309515 (2-(2,4-dichlorophenoxy)-3-(piperidin-4-yl)pyridine...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 413 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Displacement of [3H]nisoxetine from human NET expressed in HEK293 cells by scintillation proximity assay | Bioorg Med Chem Lett 20: 1114-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.023 BindingDB Entry DOI: 10.7270/Q2NS0V17 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent noradrenaline transporter (Homo sapiens (Human)) | BDBM50309507 (2-(2-fluorophenoxy)-3-(piperidin-4-yl)pyridine | C...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 536 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Displacement of [3H]nisoxetine from human NET expressed in HEK293 cells by scintillation proximity assay | Bioorg Med Chem Lett 20: 1114-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.023 BindingDB Entry DOI: 10.7270/Q2NS0V17 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Homo sapiens (Human)) | BDBM50309509 (2-(2-methoxyphenoxy)-3-(piperidin-4-yl)pyridine | ...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 610 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Displacement of [3H]citalopram from human SERT expressed in HEK293 cells by scintillation proximity assay | Bioorg Med Chem Lett 20: 1114-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.023 BindingDB Entry DOI: 10.7270/Q2NS0V17 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent noradrenaline transporter (Homo sapiens (Human)) | BDBM50309523 (1-(2-(2-chloro-6-fluorophenoxy)pyridin-3-yl)pipera...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 663 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Displacement of [3H]nisoxetine from human NET expressed in HEK293 cells by scintillation proximity assay | Bioorg Med Chem Lett 20: 1114-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.023 BindingDB Entry DOI: 10.7270/Q2NS0V17 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent serotonin transporter (Homo sapiens (Human)) | BDBM50309507 (2-(2-fluorophenoxy)-3-(piperidin-4-yl)pyridine | C...) | PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 728 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Displacement of [3H]citalopram from human SERT expressed in HEK293 cells by scintillation proximity assay | Bioorg Med Chem Lett 20: 1114-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.023 BindingDB Entry DOI: 10.7270/Q2NS0V17 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium-dependent noradrenaline transporter (Homo sapiens (Human)) | BDBM50309522 (1-(2-(2-chlorophenoxy)pyridin-3-yl)piperazine | CH...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 747 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Displacement of [3H]nisoxetine from human NET expressed in HEK293 cells by scintillation proximity assay | Bioorg Med Chem Lett 20: 1114-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.023 BindingDB Entry DOI: 10.7270/Q2NS0V17 | |||||||||||
More data for this Ligand-Target Pair |
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