Found 99 hits with Last Name = 'zeinyeh' and Initial = 'w' Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Serine/threonine-protein kinase haspin
(Homo sapiens (Human)) | BDBM50587785
![PNG](/data/jpeg/tenK5058/BindingDB_50587785.png) (CHEMBL5178368) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| Purchase
MCE PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.ejmech.2022.114369 BindingDB Entry DOI: 10.7270/Q2HQ440P |
More data for this Ligand-Target Pair | |
Serine/threonine-protein kinase haspin
(Homo sapiens (Human)) | BDBM50605473
![PNG](/data/jpeg/tenK5060/BindingDB_50605473.png) (CHEMBL5186093) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.ejmech.2022.114369 BindingDB Entry DOI: 10.7270/Q2HQ440P |
More data for this Ligand-Target Pair | |
Dual specificity protein kinase CLK1
(Mus musculus) | BDBM50587785
![PNG](/data/jpeg/tenK5058/BindingDB_50587785.png) (CHEMBL5178368) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| Purchase
MCE PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.ejmech.2022.114369 BindingDB Entry DOI: 10.7270/Q2HQ440P |
More data for this Ligand-Target Pair | |
Serine/threonine-protein kinase haspin
(Homo sapiens (Human)) | BDBM50605464
![PNG](/data/jpeg/tenK5060/BindingDB_50605464.png) (CHEMBL5188318) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.ejmech.2022.114369 BindingDB Entry DOI: 10.7270/Q2HQ440P |
More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(RAT) | BDBM50587785
![PNG](/data/jpeg/tenK5058/BindingDB_50587785.png) (CHEMBL5178368) | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| Purchase
MCE PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.ejmech.2022.114369 BindingDB Entry DOI: 10.7270/Q2HQ440P |
More data for this Ligand-Target Pair | |
Dual specificity protein kinase CLK1
(Mus musculus) | BDBM50148458
![PNG](/data/jpeg/tenK5014/BindingDB_50148458.png) (CHEMBL4778413)Show InChI InChI=1S/C18H18N2O4S/c1-19-17(21)15-8-11-16(25-15)12(9-20(2)18(11)22)10-5-6-13(23-3)14(7-10)24-4/h5-9H,1-4H3,(H,19,21) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid PDB UniChem
Patents
Similars
| PDB Article PubMed
| n/a | n/a | 18 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of human plasmin using pyroGlu-Phe-Lys-pNA.HCl |
Citation and Details
Article DOI: 10.1016/j.ejmech.2019.01.052 BindingDB Entry DOI: 10.7270/Q2BZ69NW |
More data for this Ligand-Target Pair | ![3D 3D](/images/Docked_3d.png) 3D Structure (crystal) |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(RAT) | BDBM50249773
![PNG](/data/jpeg/tenK5024/BindingDB_50249773.png) (CHEMBL4763099)Show InChI InChI=1S/C13H16N2O3S/c1-9(2)19(17,18)14-11-5-6-12-10(8-11)4-7-13(16)15(12)3/h4-9,14H,1-3H3 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of BRD9 (unknown origin) incubated in dark for 30 mins by TR-FRET assay |
Citation and Details
Article DOI: 10.1016/j.ejmech.2019.01.052 BindingDB Entry DOI: 10.7270/Q2BZ69NW |
More data for this Ligand-Target Pair | |
Dual specificity protein kinase CLK1
(Mus musculus) | BDBM50605473
![PNG](/data/jpeg/tenK5060/BindingDB_50605473.png) (CHEMBL5186093) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.ejmech.2022.114369 BindingDB Entry DOI: 10.7270/Q2HQ440P |
More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(RAT) | BDBM50249769
![PNG](/data/jpeg/tenK5024/BindingDB_50249769.png) (CHEMBL4748345)Show InChI InChI=1S/C16H14N2O3S/c1-18-15-9-8-14(11-12(15)7-10-16(18)19)22(20,21)17-13-5-3-2-4-6-13/h2-11,17H,1H3 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 23 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of BRD9 (unknown origin) incubated in dark for 30 mins by TR-FRET assay |
Citation and Details
Article DOI: 10.1016/j.ejmech.2019.01.052 BindingDB Entry DOI: 10.7270/Q2BZ69NW |
More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(RAT) | BDBM50185005
![PNG](/data/jpeg/tenK5018/BindingDB_50185005.png) (CHEMBL3823483)Show InChI InChI=1S/C11H9N5/c12-9-8-1-2-14-4-6(8)3-7-5-15-11(13)16-10(7)9/h1-5H,12H2,(H2,13,15,16) | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid PDB UniChem
Similars
| Article PubMed
| n/a | n/a | 28 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Clermont Auvergne
Curated by ChEMBL
| Assay Description Inhibition of GST-tagged rat recombinant DYRK1A expressed in Escherichia coli using myelin basic protein as substrate incubated for 30 mins in presen... |
Eur J Med Chem 118: 170-7 (2016)
Article DOI: 10.1016/j.ejmech.2016.04.004 BindingDB Entry DOI: 10.7270/Q29888XM |
More data for this Ligand-Target Pair | |
Serine/threonine-protein kinase pim-1
(Homo sapiens (Human)) | BDBM50587785
![PNG](/data/jpeg/tenK5058/BindingDB_50587785.png) (CHEMBL5178368) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| Purchase
MCE PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 29 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.ejmech.2022.114369 BindingDB Entry DOI: 10.7270/Q2HQ440P |
More data for this Ligand-Target Pair | |
Dual specificity protein kinase CLK1
(Mus musculus) | BDBM50605464
![PNG](/data/jpeg/tenK5060/BindingDB_50605464.png) (CHEMBL5188318) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 37 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.ejmech.2022.114369 BindingDB Entry DOI: 10.7270/Q2HQ440P |
More data for this Ligand-Target Pair | |
Dual specificity protein kinase CLK1
(Homo sapiens (Human)) | BDBM50185005
![PNG](/data/jpeg/tenK5018/BindingDB_50185005.png) (CHEMBL3823483)Show InChI InChI=1S/C11H9N5/c12-9-8-1-2-14-4-6(8)3-7-5-15-11(13)16-10(7)9/h1-5H,12H2,(H2,13,15,16) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid PDB UniChem
Similars
| PDB Article PubMed
| n/a | n/a | 41 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Clermont Auvergne
Curated by ChEMBL
| Assay Description Inhibition of GST-tagged human recombinant CLK1 expressed in Escherichia coli using RS peptide as substrate |
Eur J Med Chem 118: 170-7 (2016)
Article DOI: 10.1016/j.ejmech.2016.04.004 BindingDB Entry DOI: 10.7270/Q29888XM |
More data for this Ligand-Target Pair | ![3D 3D](/images/Docked_3d.png) 3D Structure (crystal) |
Cyclin-dependent kinase 5 activator 1
(Homo sapiens (Human)) | BDBM50587785
![PNG](/data/jpeg/tenK5058/BindingDB_50587785.png) (CHEMBL5178368) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| Purchase
MCE PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 41 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.ejmech.2022.114369 BindingDB Entry DOI: 10.7270/Q2HQ440P |
More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(RAT) | BDBM50605464
![PNG](/data/jpeg/tenK5060/BindingDB_50605464.png) (CHEMBL5188318) | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 47 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.ejmech.2022.114369 BindingDB Entry DOI: 10.7270/Q2HQ440P |
More data for this Ligand-Target Pair | |
Serine/threonine-protein kinase haspin
(Homo sapiens (Human)) | BDBM50605471
![PNG](/data/jpeg/tenK5060/BindingDB_50605471.png) (CHEMBL5181620) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| Purchase
MCE PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 50 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.ejmech.2022.114369 BindingDB Entry DOI: 10.7270/Q2HQ440P |
More data for this Ligand-Target Pair | |
Glycogen synthase kinase-3 beta
(Homo sapiens (Human)) | BDBM50587785
![PNG](/data/jpeg/tenK5058/BindingDB_50587785.png) (CHEMBL5178368) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| Purchase
MCE PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 53 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.ejmech.2022.114369 BindingDB Entry DOI: 10.7270/Q2HQ440P |
More data for this Ligand-Target Pair | |
Serine/threonine-protein kinase haspin
(Homo sapiens (Human)) | BDBM50605467
![PNG](/data/jpeg/tenK5060/BindingDB_50605467.png) (CHEMBL5177344) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 56 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.ejmech.2022.114369 BindingDB Entry DOI: 10.7270/Q2HQ440P |
More data for this Ligand-Target Pair | |
Dual specificity protein kinase CLK1
(Mus musculus) | BDBM50148388
![PNG](/data/jpeg/tenK5014/BindingDB_50148388.png) (CHEMBL4784564)Show InChI InChI=1S/C18H19N3O3S/c1-20-17(19)15-8-11-16(25-15)12(9-21(2)18(11)22)10-5-6-13(23-3)14(7-10)24-4/h5-9H,1-4H3,(H2,19,20) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 62 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of human plasmin using pyroGlu-Phe-Lys-pNA.HCl |
Citation and Details
Article DOI: 10.1016/j.ejmech.2019.01.052 BindingDB Entry DOI: 10.7270/Q2BZ69NW |
More data for this Ligand-Target Pair | |
Serine/threonine-protein kinase haspin
(Homo sapiens (Human)) | BDBM50605466
![PNG](/data/jpeg/tenK5060/BindingDB_50605466.png) (CHEMBL5194011) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 65 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.ejmech.2022.114369 BindingDB Entry DOI: 10.7270/Q2HQ440P |
More data for this Ligand-Target Pair | |
Serine/threonine-protein kinase haspin
(Homo sapiens (Human)) | BDBM50605471
![PNG](/data/jpeg/tenK5060/BindingDB_50605471.png) (CHEMBL5181620) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| Purchase
MCE PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 66 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.ejmech.2022.114369 BindingDB Entry DOI: 10.7270/Q2HQ440P |
More data for this Ligand-Target Pair | |
Serine/threonine-protein kinase haspin
(Homo sapiens (Human)) | BDBM50605468
![PNG](/data/jpeg/tenK5060/BindingDB_50605468.png) (CHEMBL5186471) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 69 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.ejmech.2022.114369 BindingDB Entry DOI: 10.7270/Q2HQ440P |
More data for this Ligand-Target Pair | |
Dual specificity protein kinase CLK1
(Homo sapiens (Human)) | BDBM50185004
![PNG](/data/jpeg/tenK5018/BindingDB_50185004.png) (CHEMBL3823532)Show InChI InChI=1S/C11H7N5O2/c12-11-14-5-7-3-6-4-13-2-1-8(6)10(16(17)18)9(7)15-11/h1-5H,(H2,12,14,15) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 69 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Clermont Auvergne
Curated by ChEMBL
| Assay Description Inhibition of GST-tagged human recombinant CLK1 expressed in Escherichia coli using RS peptide as substrate |
Eur J Med Chem 118: 170-7 (2016)
Article DOI: 10.1016/j.ejmech.2016.04.004 BindingDB Entry DOI: 10.7270/Q29888XM |
More data for this Ligand-Target Pair | |
Dual specificity protein kinase CLK1
(Mus musculus) | BDBM50605467
![PNG](/data/jpeg/tenK5060/BindingDB_50605467.png) (CHEMBL5177344) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 72 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.ejmech.2022.114369 BindingDB Entry DOI: 10.7270/Q2HQ440P |
More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(RAT) | BDBM50249763
![PNG](/data/jpeg/tenK5024/BindingDB_50249763.png) (CHEMBL4794934)Show InChI InChI=1S/C17H13N3O3S/c1-20-16-8-7-15(10-13(16)4-9-17(20)21)24(22,23)19-14-5-2-12(11-18)3-6-14/h2-10,19H,1H3 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 80 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Binding affinity to partial length human BRD9 by BROMOscan assay |
Citation and Details
Article DOI: 10.1016/j.ejmech.2019.01.052 BindingDB Entry DOI: 10.7270/Q2BZ69NW |
More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(RAT) | BDBM50605473
![PNG](/data/jpeg/tenK5060/BindingDB_50605473.png) (CHEMBL5186093) | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 87 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.ejmech.2022.114369 BindingDB Entry DOI: 10.7270/Q2HQ440P |
More data for this Ligand-Target Pair | |
Dual specificity protein kinase CLK1
(Mus musculus) | BDBM50509920
![PNG](/data/jpeg/tenK5050/BindingDB_50509920.png) (CHEMBL4558273)Show InChI InChI=1S/C14H14N6O2/c1-19(2)8-17-14-16-7-10-5-9-6-15-4-3-11(9)13(20(21)22)12(10)18-14/h3-7H,8H2,1-2H3,(H,16,17,18) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 87 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ Clermont Auvergne
Curated by ChEMBL
| Assay Description Inhibition of recombinant mouse CLK1 expressed in bacteria using GRSRSRSRSRSR as substrate in presence of [gamma33P]ATP |
Bioorg Med Chem 27: 2083-2089 (2019)
Article DOI: 10.1016/j.bmc.2019.04.005 BindingDB Entry DOI: 10.7270/Q25H7KKN |
More data for this Ligand-Target Pair | |
Dual specificity protein kinase CLK1
(Mus musculus) | BDBM50605466
![PNG](/data/jpeg/tenK5060/BindingDB_50605466.png) (CHEMBL5194011) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 90 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.ejmech.2022.114369 BindingDB Entry DOI: 10.7270/Q2HQ440P |
More data for this Ligand-Target Pair | |
Broad substrate specificity ATP-binding cassette transporter ABCG2
(Homo sapiens (Human)) | BDBM50305083
![PNG](/data/jpeg/tenK5030/BindingDB_50305083.png) (3-((3S,6S)-6-Isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,...)Show SMILES COc1ccc2c3C[C@@H]4N([C@@H](CC(C)C)c3[nH]c2c1)C(=O)[C@H](CCC(=O)OC(C)(C)C)NC4=O |r| Show InChI InChI=1S/C26H35N3O5/c1-14(2)11-20-23-17(16-8-7-15(33-6)12-19(16)27-23)13-21-24(31)28-18(25(32)29(20)21)9-10-22(30)34-26(3,4)5/h7-8,12,14,18,20-21,27H,9-11,13H2,1-6H3,(H,28,31)/t18-,20-,21-/m0/s1 | PDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| Purchase
CHEMBL MCE PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 90 | n/a | n/a | n/a | n/a | n/a | n/a |
BMSSI UMR 5086 CNRS/Universit£ Lyon 1
Curated by ChEMBL
| Assay Description Inhibition of ABCG2 (unknown origin) expressed in HEK293 cells assessed as reduction in mitoxantrone efflux after 30 mins by FACS method |
J Med Chem 58: 265-77 (2015)
Article DOI: 10.1021/jm500943z BindingDB Entry DOI: 10.7270/Q2V40WST |
More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(RAT) | BDBM50249774
![PNG](/data/jpeg/tenK5024/BindingDB_50249774.png) (CHEMBL4776402)Show InChI InChI=1S/C12H14N2O3S/c1-3-18(16,17)13-10-5-6-11-9(8-10)4-7-12(15)14(11)2/h4-8,13H,3H2,1-2H3 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 90 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of BRD9 (unknown origin) incubated in dark for 30 mins by TR-FRET assay |
Citation and Details
Article DOI: 10.1016/j.ejmech.2019.01.052 BindingDB Entry DOI: 10.7270/Q2BZ69NW |
More data for this Ligand-Target Pair | |
Serine/threonine-protein kinase haspin
(Homo sapiens (Human)) | BDBM50605458
![PNG](/data/jpeg/tenK5060/BindingDB_50605458.png) (CHEMBL5196946) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 91 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.ejmech.2022.114369 BindingDB Entry DOI: 10.7270/Q2HQ440P |
More data for this Ligand-Target Pair | |
Dual specificity protein kinase CLK1
(Mus musculus) | BDBM50605468
![PNG](/data/jpeg/tenK5060/BindingDB_50605468.png) (CHEMBL5186471) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 92 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.ejmech.2022.114369 BindingDB Entry DOI: 10.7270/Q2HQ440P |
More data for this Ligand-Target Pair | |
Casein kinase I isoform epsilon
(Homo sapiens (Human)) | BDBM50587785
![PNG](/data/jpeg/tenK5058/BindingDB_50587785.png) (CHEMBL5178368) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| Purchase
MCE PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 99 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.ejmech.2022.114369 BindingDB Entry DOI: 10.7270/Q2HQ440P |
More data for this Ligand-Target Pair | |
Serine/threonine-protein kinase haspin
(Homo sapiens (Human)) | BDBM50605460
![PNG](/data/jpeg/tenK5060/BindingDB_50605460.png) (CHEMBL5208358) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 114 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.ejmech.2022.114369 BindingDB Entry DOI: 10.7270/Q2HQ440P |
More data for this Ligand-Target Pair | |
Serine/threonine-protein kinase PLK3
(Homo sapiens (Human)) | BDBM50605471
![PNG](/data/jpeg/tenK5060/BindingDB_50605471.png) (CHEMBL5181620) | PDB
NCI pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| Purchase
MCE PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 117 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.ejmech.2022.114369 BindingDB Entry DOI: 10.7270/Q2HQ440P |
More data for this Ligand-Target Pair | |
Dual specificity protein kinase CLK1
(Mus musculus) | BDBM50249773
![PNG](/data/jpeg/tenK5024/BindingDB_50249773.png) (CHEMBL4763099)Show InChI InChI=1S/C13H16N2O3S/c1-9(2)19(17,18)14-11-5-6-12-10(8-11)4-7-13(16)15(12)3/h4-9,14H,1-3H3 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 117 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of BRD9 (unknown origin) incubated in dark for 30 mins by TR-FRET assay |
Citation and Details
Article DOI: 10.1016/j.ejmech.2019.01.052 BindingDB Entry DOI: 10.7270/Q2BZ69NW |
More data for this Ligand-Target Pair | |
Tyrosine-protein kinase JAK3
(Homo sapiens (Human)) | BDBM50587785
![PNG](/data/jpeg/tenK5058/BindingDB_50587785.png) (CHEMBL5178368) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| Purchase
MCE PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 119 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.ejmech.2022.114369 BindingDB Entry DOI: 10.7270/Q2HQ440P |
More data for this Ligand-Target Pair | |
Serine/threonine-protein kinase haspin
(Homo sapiens (Human)) | BDBM50605457
![PNG](/data/jpeg/tenK5060/BindingDB_50605457.png) (CHEMBL5183366) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| Purchase
MCE PC cid PC sid PDB UniChem
| PDB Article PubMed
| n/a | n/a | 119 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.ejmech.2022.114369 BindingDB Entry DOI: 10.7270/Q2HQ440P |
More data for this Ligand-Target Pair | ![3D 3D](/images/Docked_3d.png) 3D Structure (crystal) |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(RAT) | BDBM50249762
![PNG](/data/jpeg/tenK5024/BindingDB_50249762.png) (CHEMBL4759771)Show InChI InChI=1S/C13H14N2O3S/c1-15-12-6-3-10(8-9(12)2-7-13(15)16)14-19(17,18)11-4-5-11/h2-3,6-8,11,14H,4-5H2,1H3 | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 120 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of BRD9 (unknown origin) incubated in dark for 30 mins by TR-FRET assay |
Citation and Details
Article DOI: 10.1016/j.ejmech.2019.01.052 BindingDB Entry DOI: 10.7270/Q2BZ69NW |
More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(RAT) | BDBM50148459
![PNG](/data/jpeg/tenK5014/BindingDB_50148459.png) (CHEMBL4755373)Show InChI InChI=1S/C22H24N2O6S2/c1-24-12-16(13-4-5-17(29-2)18(10-13)30-3)20-15(22(24)26)11-19(31-20)21(25)23-14-6-8-32(27,28)9-7-14/h4-5,10-12,14H,6-9H2,1-3H3,(H,23,25) | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid PDB UniChem
Similars
| Article PubMed
| n/a | n/a | 120 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of BRD9 (unknown origin) incubated in dark for 30 mins by TR-FRET assay |
Citation and Details
Article DOI: 10.1016/j.ejmech.2019.01.052 BindingDB Entry DOI: 10.7270/Q2BZ69NW |
More data for this Ligand-Target Pair | |
Dual specificity protein kinase CLK1
(Mus musculus) | BDBM50249762
![PNG](/data/jpeg/tenK5024/BindingDB_50249762.png) (CHEMBL4759771)Show InChI InChI=1S/C13H14N2O3S/c1-15-12-6-3-10(8-9(12)2-7-13(15)16)14-19(17,18)11-4-5-11/h2-3,6-8,11,14H,4-5H2,1H3 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 120 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of BRD9 in human HUT78 cells incubated for 45 mins by chemoproteomic competition binding assay |
Citation and Details
Article DOI: 10.1016/j.ejmech.2019.01.052 BindingDB Entry DOI: 10.7270/Q2BZ69NW |
More data for this Ligand-Target Pair | |
Dual specificity protein kinase CLK1
(Mus musculus) | BDBM50148455
![PNG](/data/jpeg/tenK5014/BindingDB_50148455.png) (CHEMBL4791275)Show SMILES [O-][N+](=O)c1c2ccncc2cc2cnc(NCCCN3CCOCC3)nc12 Show InChI InChI=1S/C23H24F3N3O3S2/c1-13(2)29-12-18(14-4-3-5-15(10-14)23(24,25)26)20-17(22(29)30)11-19(33-20)21(27)28-16-6-8-34(31,32)9-7-16/h3-5,10-13,16H,6-9H2,1-2H3,(H2,27,28) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 120 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of human urine urokinase using L-PyroGlu-Gly-Arg-pNA.HCl substrate at 5 uM |
Citation and Details
Article DOI: 10.1016/j.ejmech.2019.01.052 BindingDB Entry DOI: 10.7270/Q2BZ69NW |
More data for this Ligand-Target Pair | |
Serine/threonine-protein kinase haspin
(Homo sapiens (Human)) | BDBM50605465
![PNG](/data/jpeg/tenK5060/BindingDB_50605465.png) (CHEMBL5202187) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 124 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.ejmech.2022.114369 BindingDB Entry DOI: 10.7270/Q2HQ440P |
More data for this Ligand-Target Pair | |
Serine/threonine-protein kinase PLK2
(Homo sapiens (Human)) | BDBM50605471
![PNG](/data/jpeg/tenK5060/BindingDB_50605471.png) (CHEMBL5181620) | PDB
NCI pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| Purchase
MCE PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 125 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.ejmech.2022.114369 BindingDB Entry DOI: 10.7270/Q2HQ440P |
More data for this Ligand-Target Pair | |
Dual specificity protein kinase CLK1
(Mus musculus) | BDBM50148457
![PNG](/data/jpeg/tenK5014/BindingDB_50148457.png) (CHEMBL4780720)Show SMILES [O-][N+](=O)c1c2ccncc2cc2cnc(NCCCN3CCCCC3)nc12 Show InChI InChI=1S/C20H21N3O3S2/c1-23-12-16(13-5-3-2-4-6-13)18-15(20(23)24)11-17(27-18)19(21)22-14-7-9-28(25,26)10-8-14/h2-6,11-12,14H,7-10H2,1H3,(H2,21,22) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 125 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of human urine urokinase using L-PyroGlu-Gly-Arg-pNA.HCl substrate at 5 uM |
Citation and Details
Article DOI: 10.1016/j.ejmech.2019.01.052 BindingDB Entry DOI: 10.7270/Q2BZ69NW |
More data for this Ligand-Target Pair | |
Broad substrate specificity ATP-binding cassette transporter ABCG2
(Homo sapiens (Human)) | BDBM50379211
![PNG](/data/jpeg/tenK5037/BindingDB_50379211.png) (CHEMBL2011288)Show SMILES COc1ccc2[nH]cc(CCNC(=O)c3cc(=O)c4c(OCc5ccc(Br)cc5)cccc4o3)c2c1 Show InChI InChI=1S/C28H23BrN2O5/c1-34-20-9-10-22-21(13-20)18(15-31-22)11-12-30-28(33)26-14-23(32)27-24(3-2-4-25(27)36-26)35-16-17-5-7-19(29)8-6-17/h2-10,13-15,31H,11-12,16H2,1H3,(H,30,33) | PDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 130 | n/a | n/a | n/a | n/a | n/a | n/a |
BMSSI UMR 5086 CNRS/Universit£ Lyon 1
Curated by ChEMBL
| Assay Description Inhibition of ABCG2 (unknown origin) expressed in HEK293 cells assessed as reduction in mitoxantrone efflux after 30 mins by FACS method |
J Med Chem 58: 265-77 (2015)
Article DOI: 10.1021/jm500943z BindingDB Entry DOI: 10.7270/Q2V40WST |
More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(RAT) | BDBM50605468
![PNG](/data/jpeg/tenK5060/BindingDB_50605468.png) (CHEMBL5186471) | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 132 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.ejmech.2022.114369 BindingDB Entry DOI: 10.7270/Q2HQ440P |
More data for this Ligand-Target Pair | |
Dual specificity protein kinase CLK1
(Mus musculus) | BDBM50148456
![PNG](/data/jpeg/tenK5014/BindingDB_50148456.png) (CHEMBL4785650)Show SMILES CN1CCN(CCCNc2ncc3cc4cnccc4c([N+]([O-])=O)c3n2)CC1 Show InChI InChI=1S/C22H25N3O5S2/c1-25-12-16(13-4-5-17(29-2)18(10-13)30-3)20-15(22(25)26)11-19(31-20)21(23)24-14-6-8-32(27,28)9-7-14/h4-5,10-12,14H,6-9H2,1-3H3,(H2,23,24) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 133 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Inhibition of human urine urokinase using L-PyroGlu-Gly-Arg-pNA.HCl substrate at 5 uM |
Citation and Details
Article DOI: 10.1016/j.ejmech.2019.01.052 BindingDB Entry DOI: 10.7270/Q2BZ69NW |
More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(RAT) | BDBM50605466
![PNG](/data/jpeg/tenK5060/BindingDB_50605466.png) (CHEMBL5194011) | PDB
UniProtKB/SwissProt
GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 148 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.ejmech.2022.114369 BindingDB Entry DOI: 10.7270/Q2HQ440P |
More data for this Ligand-Target Pair | |
Dual specificity protein kinase CLK1
(Mus musculus) | BDBM50605458
![PNG](/data/jpeg/tenK5060/BindingDB_50605458.png) (CHEMBL5196946) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet ![](/images/AffyNet_logo.png)
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 148 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.ejmech.2022.114369 BindingDB Entry DOI: 10.7270/Q2HQ440P |
More data for this Ligand-Target Pair | |