BindingDB PrimarySearch

Found 83 hits with Last Name = 'blanot' and Initial = 'd'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-lysine ligase (Staphylococcus aureus)	BDBM50248217 (1-(4-Methoxyphenylsulfonamido)-3-morpholinopropan-...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	8.0	37
University of Ljubljana					Assay Description Compounds were tested for their inhibition of the addition of L-Ala, D-Glu, L-Lys or D-Ala-D-Ala to nucleotide precursors catalyzed by MurC from Esch...				Bioorg Chem 37: 217-22 (2009) Article DOI: 10.1016/j.bioorg.2009.09.001 BindingDB Entry DOI: 10.7270/Q2D21W5D
University of Ljubljana					More data for this Ligand-Target Pair
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase (Streptococcus pneumoniae)	BDBM50447032 (CHEMBL3116334) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Ljubljana Curated by ChEMBL					Assay Description Inhibition of Streptococcus pneumoniae MurF ligase using D-Ala-D-Ala as substrate after 15 mins by malachite green assay				Eur J Med Chem 73: 83-96 (2014) Article DOI: 10.1016/j.ejmech.2013.11.031 BindingDB Entry DOI: 10.7270/Q20K2B1T
University of Ljubljana Curated by ChEMBL					More data for this Ligand-Target Pair
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase (Streptococcus pneumoniae)	BDBM50447035 (CHEMBL3116331) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Ljubljana Curated by ChEMBL					Assay Description Inhibition of Streptococcus pneumoniae MurF ligase using D-Ala-D-Ala as substrate after 15 mins by malachite green assay				Eur J Med Chem 73: 83-96 (2014) Article DOI: 10.1016/j.ejmech.2013.11.031 BindingDB Entry DOI: 10.7270/Q20K2B1T
University of Ljubljana Curated by ChEMBL					More data for this Ligand-Target Pair
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase (Streptococcus pneumoniae)	BDBM50447044 (CHEMBL3112645) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Ljubljana Curated by ChEMBL					Assay Description Inhibition of Streptococcus pneumoniae MurF ligase using D-Ala-D-Ala as substrate after 15 mins by malachite green assay				Eur J Med Chem 73: 83-96 (2014) Article DOI: 10.1016/j.ejmech.2013.11.031 BindingDB Entry DOI: 10.7270/Q20K2B1T
University of Ljubljana Curated by ChEMBL					More data for this Ligand-Target Pair
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase (Streptococcus pneumoniae)	BDBM50447037 (CHEMBL3116329) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Ljubljana Curated by ChEMBL					Assay Description Inhibition of Streptococcus pneumoniae MurF ligase using D-Ala-D-Ala as substrate after 15 mins by malachite green assay				Eur J Med Chem 73: 83-96 (2014) Article DOI: 10.1016/j.ejmech.2013.11.031 BindingDB Entry DOI: 10.7270/Q20K2B1T
University of Ljubljana Curated by ChEMBL					More data for this Ligand-Target Pair
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-lysine ligase (Staphylococcus aureus)	BDBM85276 (HEA derivative, 7c \| MurC/D/E/F inhibitor (compoun...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.70E+4	n/a	n/a	n/a	n/a	8.0	37
University of Ljubljana					Assay Description Compounds were tested for their inhibition of the addition of L-Ala, D-Glu, L-Lys or D-Ala-D-Ala to nucleotide precursors catalyzed by MurC from Esch...				Bioorg Chem 37: 217-22 (2009) Article DOI: 10.1016/j.bioorg.2009.09.001 BindingDB Entry DOI: 10.7270/Q2D21W5D
University of Ljubljana					More data for this Ligand-Target Pair
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase (Streptococcus pneumoniae)	BDBM50447048 (CHEMBL3112637) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Ljubljana Curated by ChEMBL					Assay Description Inhibition of Streptococcus pneumoniae MurF ligase using D-Ala-D-Ala as substrate after 15 mins by malachite green assay				Eur J Med Chem 73: 83-96 (2014) Article DOI: 10.1016/j.ejmech.2013.11.031 BindingDB Entry DOI: 10.7270/Q20K2B1T
University of Ljubljana Curated by ChEMBL					More data for this Ligand-Target Pair
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase (Streptococcus pneumoniae)	BDBM50447033 (CHEMBL3116333) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Ljubljana Curated by ChEMBL					Assay Description Inhibition of Streptococcus pneumoniae MurF ligase using D-Ala-D-Ala as substrate after 15 mins by malachite green assay				Eur J Med Chem 73: 83-96 (2014) Article DOI: 10.1016/j.ejmech.2013.11.031 BindingDB Entry DOI: 10.7270/Q20K2B1T
University of Ljubljana Curated by ChEMBL					More data for this Ligand-Target Pair
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-lysine ligase (Staphylococcus aureus)	BDBM85279 (HEA derivative, 7f) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.10E+4	n/a	n/a	n/a	n/a	8.0	37
University of Ljubljana					Assay Description Compounds were tested for their inhibition of the addition of L-Ala, D-Glu, L-Lys or D-Ala-D-Ala to nucleotide precursors catalyzed by MurC from Esch...				Bioorg Chem 37: 217-22 (2009) Article DOI: 10.1016/j.bioorg.2009.09.001 BindingDB Entry DOI: 10.7270/Q2D21W5D
University of Ljubljana					More data for this Ligand-Target Pair
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase (Streptococcus pneumoniae)	BDBM50447036 (CHEMBL3116330) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Ljubljana Curated by ChEMBL					Assay Description Inhibition of Streptococcus pneumoniae MurF ligase using D-Ala-D-Ala as substrate after 15 mins by malachite green assay				Eur J Med Chem 73: 83-96 (2014) Article DOI: 10.1016/j.ejmech.2013.11.031 BindingDB Entry DOI: 10.7270/Q20K2B1T
University of Ljubljana Curated by ChEMBL					More data for this Ligand-Target Pair
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase (Streptococcus pneumoniae)	BDBM50447050 (CHEMBL3112632) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Ljubljana Curated by ChEMBL					Assay Description Inhibition of Streptococcus pneumoniae MurF ligase using D-Ala-D-Ala as substrate after 15 mins by malachite green assay				Eur J Med Chem 73: 83-96 (2014) Article DOI: 10.1016/j.ejmech.2013.11.031 BindingDB Entry DOI: 10.7270/Q20K2B1T
University of Ljubljana Curated by ChEMBL					More data for this Ligand-Target Pair
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase (Streptococcus pneumoniae)	BDBM50447049 (CHEMBL3112633) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Ljubljana Curated by ChEMBL					Assay Description Inhibition of Streptococcus pneumoniae MurF ligase using D-Ala-D-Ala as substrate after 15 mins by malachite green assay				Eur J Med Chem 73: 83-96 (2014) Article DOI: 10.1016/j.ejmech.2013.11.031 BindingDB Entry DOI: 10.7270/Q20K2B1T
University of Ljubljana Curated by ChEMBL					More data for this Ligand-Target Pair
UDP-N-acetylmuramoylalanine--D-glutamate ligase (Escherichia coli (strain K12))	BDBM50176461 (2-(hydroxy-{1-[(R)-2-(4-nitro-phenylmethanesulfony...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Ljubljana Curated by ChEMBL					Assay Description Inhibitory activity against MurD from Escherichia coli				Bioorg Med Chem Lett 16: 343-8 (2005) Article DOI: 10.1016/j.bmcl.2005.09.086 BindingDB Entry DOI: 10.7270/Q2FF3RZX
University of Ljubljana Curated by ChEMBL					More data for this Ligand-Target Pair
UDP-N-acetylmuramoylalanine--D-glutamate ligase (Escherichia coli (strain K12))	BDBM26455 ((2R)-2-({6-[(4-cyano-2-fluorophenyl)methoxy]naphth...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	DrugBank MMDB PC cid PC sid PDB UniChem Similars	DrugBank MMDB PDB Article PubMed	n/a	n/a	8.50E+4	n/a	n/a	n/a	n/a	8.6	37
Lek Pharmaceuticals d.d.					Assay Description The compounds were tested for their ability to inhibit the addition of D-[14C]Glu to UMA. The radioactive substrate and product were separated by re...				J Med Chem 51: 7486-94 (2008) Article DOI: 10.1021/jm800762u BindingDB Entry DOI: 10.7270/Q2B27SMN
Lek Pharmaceuticals d.d.					More data for this Ligand-Target Pair				3D Structure (crystal)
UDP-N-acetylmuramoylalanine--D-glutamate ligase (Escherichia coli (strain K12))	BDBM50176463 (2-{[1-((E)-3-benzo[1,3]dioxol-5-yl-acryloylamino)-...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Ljubljana Curated by ChEMBL					Assay Description Inhibitory activity against MurD from Escherichia coli				Bioorg Med Chem Lett 16: 343-8 (2005) Article DOI: 10.1016/j.bmcl.2005.09.086 BindingDB Entry DOI: 10.7270/Q2FF3RZX
University of Ljubljana Curated by ChEMBL					More data for this Ligand-Target Pair
UDP-N-acetylmuramoylalanine--D-glutamate ligase (Escherichia coli (strain K12))	BDBM26454 ((2R)-2-({6-[(4-cyano-2-methoxyphenyl)methoxy]napht...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+5	n/a	n/a	n/a	n/a	8.6	37
Lek Pharmaceuticals d.d.					Assay Description The compounds were tested for their ability to inhibit the addition of D-[14C]Glu to UMA. The radioactive substrate and product were separated by re...				J Med Chem 51: 7486-94 (2008) Article DOI: 10.1021/jm800762u BindingDB Entry DOI: 10.7270/Q2B27SMN
Lek Pharmaceuticals d.d.					More data for this Ligand-Target Pair				3D Structure (docked)
UDP-N-acetylmuramoylalanine--D-glutamate ligase (Streptococcus pneumoniae)	BDBM50176464 (2-[(1-benzyloxycarbonylamino-ethyl)-hydroxy-phosph...) Show SMILES Show InChI	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Ljubljana Curated by ChEMBL					Assay Description Inhibitory activity against MurD from Streptococcus pneumoniae				Bioorg Med Chem Lett 16: 343-8 (2005) Article DOI: 10.1016/j.bmcl.2005.09.086 BindingDB Entry DOI: 10.7270/Q2FF3RZX
University of Ljubljana Curated by ChEMBL					More data for this Ligand-Target Pair
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase (Streptococcus pneumoniae)	BDBM50447045 (CHEMBL3112644) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.03E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Ljubljana Curated by ChEMBL					Assay Description Inhibition of Streptococcus pneumoniae MurF ligase using D-Ala-D-Ala as substrate after 15 mins by malachite green assay				Eur J Med Chem 73: 83-96 (2014) Article DOI: 10.1016/j.ejmech.2013.11.031 BindingDB Entry DOI: 10.7270/Q20K2B1T
University of Ljubljana Curated by ChEMBL					More data for this Ligand-Target Pair
UDP-N-acetylmuramoylalanine--D-glutamate ligase (Escherichia coli (strain K12))	BDBM26453 ((2R)-2-({6-[(4-cyanophenyl)methoxy]naphthalene-2-}...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	DrugBank MMDB PC cid PC sid PDB UniChem Similars	DrugBank MMDB PDB Article PubMed	n/a	n/a	1.05E+5	n/a	n/a	n/a	n/a	8.6	37
Lek Pharmaceuticals d.d.					Assay Description The compounds were tested for their ability to inhibit the addition of D-[14C]Glu to UMA. The radioactive substrate and product were separated by re...				J Med Chem 51: 7486-94 (2008) Article DOI: 10.1021/jm800762u BindingDB Entry DOI: 10.7270/Q2B27SMN
Lek Pharmaceuticals d.d.					More data for this Ligand-Target Pair				3D Structure (crystal)
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase (Streptococcus pneumoniae)	BDBM50447040 (CHEMBL3116326) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.07E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Ljubljana Curated by ChEMBL					Assay Description Inhibition of Streptococcus pneumoniae MurF ligase using D-Ala-D-Ala as substrate after 15 mins by malachite green assay				Eur J Med Chem 73: 83-96 (2014) Article DOI: 10.1016/j.ejmech.2013.11.031 BindingDB Entry DOI: 10.7270/Q20K2B1T
University of Ljubljana Curated by ChEMBL					More data for this Ligand-Target Pair
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase (Streptococcus pneumoniae)	BDBM50447038 (CHEMBL3116328) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.09E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Ljubljana Curated by ChEMBL					Assay Description Inhibition of Streptococcus pneumoniae MurF ligase using D-Ala-D-Ala as substrate after 15 mins by malachite green assay				Eur J Med Chem 73: 83-96 (2014) Article DOI: 10.1016/j.ejmech.2013.11.031 BindingDB Entry DOI: 10.7270/Q20K2B1T
University of Ljubljana Curated by ChEMBL					More data for this Ligand-Target Pair
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase (Streptococcus pneumoniae)	BDBM50447034 (CHEMBL3116332) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.17E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Ljubljana Curated by ChEMBL					Assay Description Inhibition of Streptococcus pneumoniae MurF ligase using D-Ala-D-Ala as substrate after 15 mins by malachite green assay				Eur J Med Chem 73: 83-96 (2014) Article DOI: 10.1016/j.ejmech.2013.11.031 BindingDB Entry DOI: 10.7270/Q20K2B1T
University of Ljubljana Curated by ChEMBL					More data for this Ligand-Target Pair
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase (Streptococcus pneumoniae)	BDBM50447041 (CHEMBL3112648) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.19E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Ljubljana Curated by ChEMBL					Assay Description Inhibition of Streptococcus pneumoniae MurF ligase using D-Ala-D-Ala as substrate after 15 mins by malachite green assay				Eur J Med Chem 73: 83-96 (2014) Article DOI: 10.1016/j.ejmech.2013.11.031 BindingDB Entry DOI: 10.7270/Q20K2B1T
University of Ljubljana Curated by ChEMBL					More data for this Ligand-Target Pair
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-lysine ligase (Staphylococcus aureus)	BDBM85278 (HEA derivative, 7e) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20E+5	n/a	n/a	n/a	n/a	8.0	37
University of Ljubljana					Assay Description Compounds were tested for their inhibition of the addition of L-Ala, D-Glu, L-Lys or D-Ala-D-Ala to nucleotide precursors catalyzed by MurC from Esch...				Bioorg Chem 37: 217-22 (2009) Article DOI: 10.1016/j.bioorg.2009.09.001 BindingDB Entry DOI: 10.7270/Q2D21W5D
University of Ljubljana					More data for this Ligand-Target Pair
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-lysine ligase (Staphylococcus aureus)	BDBM50248218 (1-(4-Fluorophenylsulfonamido)-3-morpholinopropan-2...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20E+5	n/a	n/a	n/a	n/a	8.0	37
University of Ljubljana					Assay Description Compounds were tested for their inhibition of the addition of L-Ala, D-Glu, L-Lys or D-Ala-D-Ala to nucleotide precursors catalyzed by MurC from Esch...				Bioorg Chem 37: 217-22 (2009) Article DOI: 10.1016/j.bioorg.2009.09.001 BindingDB Entry DOI: 10.7270/Q2D21W5D
University of Ljubljana					More data for this Ligand-Target Pair
UDP-N-acetylmuramoylalanine--D-glutamate ligase (Escherichia coli (strain K12))	BDBM26456 ((2R)-2-({7-[(4-cyanophenyl)methoxy]naphthalene-2-}...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	MMDB PC cid PC sid PDB UniChem Similars	MMDB PDB Article PubMed	n/a	n/a	1.22E+5	n/a	n/a	n/a	n/a	8.6	37
Lek Pharmaceuticals d.d.					Assay Description The compounds were tested for their ability to inhibit the addition of D-[14C]Glu to UMA. The radioactive substrate and product were separated by re...				J Med Chem 51: 7486-94 (2008) Article DOI: 10.1021/jm800762u BindingDB Entry DOI: 10.7270/Q2B27SMN
Lek Pharmaceuticals d.d.					More data for this Ligand-Target Pair				3D Structure (crystal)
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase (Streptococcus pneumoniae)	BDBM50447043 (CHEMBL3112646) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.25E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Ljubljana Curated by ChEMBL					Assay Description Inhibition of Streptococcus pneumoniae MurF ligase using D-Ala-D-Ala as substrate after 15 mins by malachite green assay				Eur J Med Chem 73: 83-96 (2014) Article DOI: 10.1016/j.ejmech.2013.11.031 BindingDB Entry DOI: 10.7270/Q20K2B1T
University of Ljubljana Curated by ChEMBL					More data for this Ligand-Target Pair
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase (Streptococcus pneumoniae)	BDBM50447055 (CHEMBL3112590) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.26E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Ljubljana Curated by ChEMBL					Assay Description Inhibition of Streptococcus pneumoniae MurF ligase using D-Ala-D-Ala as substrate after 15 mins by malachite green assay				Eur J Med Chem 73: 83-96 (2014) Article DOI: 10.1016/j.ejmech.2013.11.031 BindingDB Entry DOI: 10.7270/Q20K2B1T
University of Ljubljana Curated by ChEMBL					More data for this Ligand-Target Pair
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase (Streptococcus pneumoniae)	BDBM50447052 (CHEMBL3112630) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.28E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Ljubljana Curated by ChEMBL					Assay Description Inhibition of Streptococcus pneumoniae MurF ligase using D-Ala-D-Ala as substrate after 15 mins by malachite green assay				Eur J Med Chem 73: 83-96 (2014) Article DOI: 10.1016/j.ejmech.2013.11.031 BindingDB Entry DOI: 10.7270/Q20K2B1T
University of Ljubljana Curated by ChEMBL					More data for this Ligand-Target Pair
UDP-N-acetylmuramoylalanine--D-glutamate ligase (Escherichia coli (strain K12))	BDBM26452 ((2R)-2-{[6-(3-phenylpropoxy)naphthalene-2-]sulfona...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.32E+5	n/a	n/a	n/a	n/a	8.6	37
Lek Pharmaceuticals d.d.					Assay Description The compounds were tested for their ability to inhibit the addition of D-[14C]Glu to UMA. The radioactive substrate and product were separated by re...				J Med Chem 51: 7486-94 (2008) Article DOI: 10.1021/jm800762u BindingDB Entry DOI: 10.7270/Q2B27SMN
Lek Pharmaceuticals d.d.					More data for this Ligand-Target Pair				3D Structure (docked)
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase (Escherichia coli)	BDBM85277 (HEA derivative, 7d) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.50E+5	n/a	n/a	n/a	n/a	8.0	37
University of Ljubljana					Assay Description Compounds were tested for their inhibition of the addition of L-Ala, D-Glu, L-Lys or D-Ala-D-Ala to nucleotide precursors catalyzed by MurC from Esch...				Bioorg Chem 37: 217-22 (2009) Article DOI: 10.1016/j.bioorg.2009.09.001 BindingDB Entry DOI: 10.7270/Q2D21W5D
University of Ljubljana					More data for this Ligand-Target Pair
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase (Streptococcus pneumoniae)	BDBM50447046 (CHEMBL3112640) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.54E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Ljubljana Curated by ChEMBL					Assay Description Inhibition of Streptococcus pneumoniae MurF ligase using D-Ala-D-Ala as substrate after 15 mins by malachite green assay				Eur J Med Chem 73: 83-96 (2014) Article DOI: 10.1016/j.ejmech.2013.11.031 BindingDB Entry DOI: 10.7270/Q20K2B1T
University of Ljubljana Curated by ChEMBL					More data for this Ligand-Target Pair
UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-lysine ligase (Staphylococcus aureus)	BDBM85277 (HEA derivative, 7d) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60E+5	n/a	n/a	n/a	n/a	8.0	37
University of Ljubljana					Assay Description Compounds were tested for their inhibition of the addition of L-Ala, D-Glu, L-Lys or D-Ala-D-Ala to nucleotide precursors catalyzed by MurC from Esch...				Bioorg Chem 37: 217-22 (2009) Article DOI: 10.1016/j.bioorg.2009.09.001 BindingDB Entry DOI: 10.7270/Q2D21W5D
University of Ljubljana					More data for this Ligand-Target Pair
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase (Streptococcus pneumoniae)	BDBM50447051 (CHEMBL3112631) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.67E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Ljubljana Curated by ChEMBL					Assay Description Inhibition of Streptococcus pneumoniae MurF ligase using D-Ala-D-Ala as substrate after 15 mins by malachite green assay				Eur J Med Chem 73: 83-96 (2014) Article DOI: 10.1016/j.ejmech.2013.11.031 BindingDB Entry DOI: 10.7270/Q20K2B1T
University of Ljubljana Curated by ChEMBL					More data for this Ligand-Target Pair
UDP-N-acetylmuramoylalanine--D-glutamate ligase (Escherichia coli (strain K12))	BDBM26445 ((2R)-2-{[6-(pentyloxy)naphthalene-2-]sulfonamido}p...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	DrugBank MMDB PC cid PC sid PDB UniChem Similars	DrugBank MMDB PDB Article PubMed	n/a	n/a	1.70E+5	n/a	n/a	n/a	n/a	8.6	37
Lek Pharmaceuticals d.d.					Assay Description The compounds were tested for their ability to inhibit the addition of D-[14C]Glu to UMA. The radioactive substrate and product were separated by re...				J Med Chem 51: 7486-94 (2008) Article DOI: 10.1021/jm800762u BindingDB Entry DOI: 10.7270/Q2B27SMN
Lek Pharmaceuticals d.d.					More data for this Ligand-Target Pair				3D Structure (crystal)
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase (Streptococcus pneumoniae)	BDBM50447053 (CHEMBL3112629) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.70E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Ljubljana Curated by ChEMBL					Assay Description Inhibition of Streptococcus pneumoniae MurF ligase using D-Ala-D-Ala as substrate after 15 mins by malachite green assay				Eur J Med Chem 73: 83-96 (2014) Article DOI: 10.1016/j.ejmech.2013.11.031 BindingDB Entry DOI: 10.7270/Q20K2B1T
University of Ljubljana Curated by ChEMBL					More data for this Ligand-Target Pair
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase (Streptococcus pneumoniae)	BDBM50447047 (CHEMBL3112639) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.72E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Ljubljana Curated by ChEMBL					Assay Description Inhibition of Streptococcus pneumoniae MurF ligase using D-Ala-D-Ala as substrate after 15 mins by malachite green assay				Eur J Med Chem 73: 83-96 (2014) Article DOI: 10.1016/j.ejmech.2013.11.031 BindingDB Entry DOI: 10.7270/Q20K2B1T
University of Ljubljana Curated by ChEMBL					More data for this Ligand-Target Pair
UDP-N-acetylmuramoylalanine--D-glutamate ligase (Escherichia coli (strain K12))	BDBM26446 ((2R)-2-{[6-(hexyloxy)naphthalene-2-]sulfonamido}pe...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.76E+5	n/a	n/a	n/a	n/a	8.6	37
Lek Pharmaceuticals d.d.					Assay Description The compounds were tested for their ability to inhibit the addition of D-[14C]Glu to UMA. The radioactive substrate and product were separated by re...				J Med Chem 51: 7486-94 (2008) Article DOI: 10.1021/jm800762u BindingDB Entry DOI: 10.7270/Q2B27SMN
Lek Pharmaceuticals d.d.					More data for this Ligand-Target Pair				3D Structure (docked)
UDP-N-acetylmuramoylalanine--D-glutamate ligase (Escherichia coli (strain K12))	BDBM26464 ((2R)-2-[(7-butoxynaphthalene-2-)sulfonamido]pentan...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.80E+5	n/a	n/a	n/a	n/a	n/a	n/a
Lek Pharmaceuticals d.d.					Assay Description The compounds were tested for their ability to inhibit the addition of D-[14C]Glu to UMA. The radioactive substrate and product were separated by re...				J Med Chem 51: 7486-94 (2008) Article DOI: 10.1021/jm800762u BindingDB Entry DOI: 10.7270/Q2B27SMN
Lek Pharmaceuticals d.d.					More data for this Ligand-Target Pair				3D Structure (docked)
UDP-N-acetylmuramoylalanine--D-glutamate ligase (Escherichia coli (strain K12))	BDBM26447 ((2R)-2-{[6-(2-ethoxy-2-oxoethoxy)naphthalene-2-]su...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.92E+5	n/a	n/a	n/a	n/a	8.6	37
Lek Pharmaceuticals d.d.					Assay Description The compounds were tested for their ability to inhibit the addition of D-[14C]Glu to UMA. The radioactive substrate and product were separated by re...				J Med Chem 51: 7486-94 (2008) Article DOI: 10.1021/jm800762u BindingDB Entry DOI: 10.7270/Q2B27SMN
Lek Pharmaceuticals d.d.					More data for this Ligand-Target Pair
UDP-N-acetylmuramate--L-alanine ligase (Escherichia coli)	BDBM85276 (HEA derivative, 7c \| MurC/D/E/F inhibitor (compoun...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+5	n/a	n/a	n/a	n/a	8.0	37
University of Ljubljana					Assay Description Compounds were tested for their inhibition of the addition of L-Ala, D-Glu, L-Lys or D-Ala-D-Ala to nucleotide precursors catalyzed by MurC from Esch...				Bioorg Chem 37: 217-22 (2009) Article DOI: 10.1016/j.bioorg.2009.09.001 BindingDB Entry DOI: 10.7270/Q2D21W5D
University of Ljubljana					More data for this Ligand-Target Pair
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase (Streptococcus pneumoniae)	BDBM50447054 (CHEMBL3112649) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.19E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Ljubljana Curated by ChEMBL					Assay Description Inhibition of Streptococcus pneumoniae MurF ligase using D-Ala-D-Ala as substrate after 15 mins by malachite green assay				Eur J Med Chem 73: 83-96 (2014) Article DOI: 10.1016/j.ejmech.2013.11.031 BindingDB Entry DOI: 10.7270/Q20K2B1T
University of Ljubljana Curated by ChEMBL					More data for this Ligand-Target Pair
UDP-N-acetylmuramoylalanine--D-glutamate ligase (Escherichia coli (strain K12))	BDBM26451 ((2R)-2-{[6-(benzyloxy)naphthalene-2-]sulfonamido}p...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.39E+5	n/a	n/a	n/a	n/a	8.6	37
Lek Pharmaceuticals d.d.					Assay Description The compounds were tested for their ability to inhibit the addition of D-[14C]Glu to UMA. The radioactive substrate and product were separated by re...				J Med Chem 51: 7486-94 (2008) Article DOI: 10.1021/jm800762u BindingDB Entry DOI: 10.7270/Q2B27SMN
Lek Pharmaceuticals d.d.					More data for this Ligand-Target Pair				3D Structure (docked)
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase (Escherichia coli)	BDBM85276 (HEA derivative, 7c \| MurC/D/E/F inhibitor (compoun...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.40E+5	n/a	n/a	n/a	n/a	8.0	37
University of Ljubljana					Assay Description Compounds were tested for their inhibition of the addition of L-Ala, D-Glu, L-Lys or D-Ala-D-Ala to nucleotide precursors catalyzed by MurC from Esch...				Bioorg Chem 37: 217-22 (2009) Article DOI: 10.1016/j.bioorg.2009.09.001 BindingDB Entry DOI: 10.7270/Q2D21W5D
University of Ljubljana					More data for this Ligand-Target Pair
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase (Escherichia coli)	BDBM50248218 (1-(4-Fluorophenylsulfonamido)-3-morpholinopropan-2...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.70E+5	n/a	n/a	n/a	n/a	8.0	37
University of Ljubljana					Assay Description Compounds were tested for their inhibition of the addition of L-Ala, D-Glu, L-Lys or D-Ala-D-Ala to nucleotide precursors catalyzed by MurC from Esch...				Bioorg Chem 37: 217-22 (2009) Article DOI: 10.1016/j.bioorg.2009.09.001 BindingDB Entry DOI: 10.7270/Q2D21W5D
University of Ljubljana					More data for this Ligand-Target Pair
UDP-N-acetylmuramoylalanine--D-glutamate ligase (Escherichia coli (strain K12))	BDBM26444 ((2R)-2-[(6-butoxynaphthalene-2-)sulfonamido]pentan...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	MMDB PC cid PC sid PDB UniChem Similars	MMDB PDB Article PubMed	n/a	n/a	2.80E+5	n/a	n/a	n/a	n/a	8.6	37
Lek Pharmaceuticals d.d.					Assay Description The compounds were tested for their ability to inhibit the addition of D-[14C]Glu to UMA. The radioactive substrate and product were separated by re...				J Med Chem 51: 7486-94 (2008) Article DOI: 10.1021/jm800762u BindingDB Entry DOI: 10.7270/Q2B27SMN
Lek Pharmaceuticals d.d.					More data for this Ligand-Target Pair				3D Structure (crystal)
UDP-N-acetylmuramoylalanine--D-glutamate ligase (Escherichia coli (strain K12))	BDBM26443 ((2R)-2-[(6-propoxynaphthalene-2-)sulfonamido]penta...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.05E+5	n/a	n/a	n/a	n/a	8.6	37
Lek Pharmaceuticals d.d.					Assay Description The compounds were tested for their ability to inhibit the addition of D-[14C]Glu to UMA. The radioactive substrate and product were separated by re...				J Med Chem 51: 7486-94 (2008) Article DOI: 10.1021/jm800762u BindingDB Entry DOI: 10.7270/Q2B27SMN
Lek Pharmaceuticals d.d.					More data for this Ligand-Target Pair				3D Structure (docked)
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase (Escherichia coli)	BDBM85279 (HEA derivative, 7f) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.60E+5	n/a	n/a	n/a	n/a	8.0	37
University of Ljubljana					Assay Description Compounds were tested for their inhibition of the addition of L-Ala, D-Glu, L-Lys or D-Ala-D-Ala to nucleotide precursors catalyzed by MurC from Esch...				Bioorg Chem 37: 217-22 (2009) Article DOI: 10.1016/j.bioorg.2009.09.001 BindingDB Entry DOI: 10.7270/Q2D21W5D
University of Ljubljana					More data for this Ligand-Target Pair
UDP-N-acetylmuramoylalanine--D-glutamate ligase (Escherichia coli (strain K12))	BDBM26450 ((2R)-2-{[6-(cyclopentyloxy)naphthalene-2-]sulfonam...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.00E+5	n/a	n/a	n/a	n/a	8.6	37
Lek Pharmaceuticals d.d.					Assay Description The compounds were tested for their ability to inhibit the addition of D-[14C]Glu to UMA. The radioactive substrate and product were separated by re...				J Med Chem 51: 7486-94 (2008) Article DOI: 10.1021/jm800762u BindingDB Entry DOI: 10.7270/Q2B27SMN
Lek Pharmaceuticals d.d.					More data for this Ligand-Target Pair				3D Structure (docked)
UDP-N-acetylmuramoylalanine--D-glutamate ligase (Escherichia coli (strain K12))	BDBM50176462 (2-(hydroxy-{1-[(E)-(3-phenyl-acryloyl)amino]-ethyl...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.32E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Ljubljana Curated by ChEMBL					Assay Description Inhibitory activity against MurD from Escherichia coli				Bioorg Med Chem Lett 16: 343-8 (2005) Article DOI: 10.1016/j.bmcl.2005.09.086 BindingDB Entry DOI: 10.7270/Q2FF3RZX
University of Ljubljana Curated by ChEMBL					More data for this Ligand-Target Pair

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