Compile Data Set for Download or QSAR

Found 96 hits with Last Name = 'champion' and Initial = 'e'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50025103 (CHEMBL41301 | Sodium; 4-{4-[3-(4-acetyl-3-hydroxy-...) Show SMILES CCCc1c(O)c(ccc1OCCCSc1ccc(cc1)C(O)[C@@H](C)CC([O-])=O)C(C)=O Show InChI InChI=1S/C25H32O6S/c1-4-6-21-22(12-11-20(17(3)26)25(21)30)31-13-5-14-32-19-9-7-18(8-10-19)24(29)16(2)15-23(27)28/h7-12,16,24,29-30H,4-6,13-15H2,1-3H3,(H,27,28)/p-1/t16-,24?/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was tested for inhibition of radioligand [3H]-LTD4 binding to Cysteinyl leukotriene D4 receptor in guinea pig lung membranes				J Med Chem 29: 1573-6 (1986) BindingDB Entry DOI: 10.7270/Q21G0K8C
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50025103 (CHEMBL41301 | Sodium; 4-{4-[3-(4-acetyl-3-hydroxy-...) Show SMILES CCCc1c(O)c(ccc1OCCCSc1ccc(cc1)C(O)[C@@H](C)CC([O-])=O)C(C)=O Show InChI InChI=1S/C25H32O6S/c1-4-6-21-22(12-11-20(17(3)26)25(21)30)31-13-5-14-32-19-9-7-18(8-10-19)24(29)16(2)15-23(27)28/h7-12,16,24,29-30H,4-6,13-15H2,1-3H3,(H,27,28)/p-1/t16-,24?/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	8.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Compound was tested for inhibition of radioligand [3H]-LTC4 binding to Cysteinyl leukotriene D4 receptor in guinea pig lung membranes				J Med Chem 29: 1573-6 (1986) BindingDB Entry DOI: 10.7270/Q21G0K8C
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50280701 (CHEMBL275357 | Sodium; (R)-3-{(R)-1-[3-(7-chloro-q...) Show SMILES C[C@@H](CS[C@H](CCc1ccccc1C(C)(C)O)c1cccc(OCc2ccc3ccc(Cl)cc3n2)c1)C([O-])=O Show InChI InChI=1S/C32H34ClNO4S/c1-21(31(35)36)20-39-30(16-13-22-7-4-5-10-28(22)32(2,3)37)24-8-6-9-27(17-24)38-19-26-15-12-23-11-14-25(33)18-29(23)34-26/h4-12,14-15,17-18,21,30,37H,13,16,19-20H2,1-3H3,(H,35,36)/p-1/t21-,30+/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory concentration against [3H]-Leukotriene D4 binding to guinea-pig lung membranes was determined; experiment 2				Bioorg Med Chem Lett 2: 1141-1146 (1992) Article DOI: 10.1016/S0960-894X(00)80635-6 BindingDB Entry DOI: 10.7270/Q2D21XJR
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50280701 (CHEMBL275357 | Sodium; (R)-3-{(R)-1-[3-(7-chloro-q...) Show SMILES C[C@@H](CS[C@H](CCc1ccccc1C(C)(C)O)c1cccc(OCc2ccc3ccc(Cl)cc3n2)c1)C([O-])=O Show InChI InChI=1S/C32H34ClNO4S/c1-21(31(35)36)20-39-30(16-13-22-7-4-5-10-28(22)32(2,3)37)24-8-6-9-27(17-24)38-19-26-15-12-23-11-14-25(33)18-29(23)34-26/h4-12,14-15,17-18,21,30,37H,13,16,19-20H2,1-3H3,(H,35,36)/p-1/t21-,30+/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory concentration against [3H]-Leukotriene D4 binding to guinea-pig lung membranes was determined; experiment 1				Bioorg Med Chem Lett 2: 1141-1146 (1992) Article DOI: 10.1016/S0960-894X(00)80635-6 BindingDB Entry DOI: 10.7270/Q2D21XJR
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50001273 (3-((2-Carbamoyl-ethylsulfanyl)-{3-[2-(7-chloro-qui...) Show SMILES NC(=O)CCSC(SCCC(O)=O)c1cccc(\C=C\c2ccc3ccc(Cl)cc3n2)c1 Show InChI InChI=1S/C24H23ClN2O3S2/c25-19-7-5-17-6-9-20(27-21(17)15-19)8-4-16-2-1-3-18(14-16)24(31-12-10-22(26)28)32-13-11-23(29)30/h1-9,14-15,24H,10-13H2,(H2,26,28)(H,29,30)/b8-4+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description In vitro inhibition of [3H]LTD4 binding to guinea pig lung membranes				J Med Chem 35: 3832-44 (1992) BindingDB Entry DOI: 10.7270/Q2TQ625N
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50280712 (CHEMBL14819 | Sodium; 3-{1-[3-(7-chloro-quinolin-2...) Show SMILES [O-]C(=O)CCSC(CCc1ccccc1-c1nnc[nH]1)c1cccc(OCc2ccc3ccc(Cl)cc3n2)c1 Show InChI InChI=1S/C30H27ClN4O3S/c31-23-11-8-21-9-12-24(34-27(21)17-23)18-38-25-6-3-5-22(16-25)28(39-15-14-29(36)37)13-10-20-4-1-2-7-26(20)30-32-19-33-35-30/h1-9,11-12,16-17,19,28H,10,13-15,18H2,(H,36,37)(H,32,33,35)/p-1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	0.360	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory concentration against [3H]-Leukotriene D4 binding to guinea-pig lung membranes was determined				Bioorg Med Chem Lett 2: 1141-1146 (1992) Article DOI: 10.1016/S0960-894X(00)80635-6 BindingDB Entry DOI: 10.7270/Q2D21XJR
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50280693 (CHEMBL15370 | Sodium; 3-[1-[3-(7-chloro-quinolin-2...) Show SMILES CC(CSC(CCc1ccccc1[N+]([O-])=O)c1cccc(OCc2ccc3ccc(Cl)cc3n2)c1)C([O-])=O Show InChI InChI=1S/C29H27ClN2O5S/c1-19(29(33)34)18-38-28(14-11-21-5-2-3-8-27(21)32(35)36)22-6-4-7-25(15-22)37-17-24-13-10-20-9-12-23(30)16-26(20)31-24/h2-10,12-13,15-16,19,28H,11,14,17-18H2,1H3,(H,33,34)/p-1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory concentration against [3H]-Leukotriene D4 binding to guinea-pig lung membranes was determined; experiment 2				Bioorg Med Chem Lett 2: 1141-1146 (1992) Article DOI: 10.1016/S0960-894X(00)80635-6 BindingDB Entry DOI: 10.7270/Q2D21XJR
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50280713 (CHEMBL15232 | Sodium; 2-{1-[3-(7-chloro-quinolin-2...) Show SMILES CCC(CSC(CCc1ccccc1-c1nnnn1C)c1cccc(OCc2ccc3ccc(Cl)cc3n2)c1)C([O-])=O Show InChI InChI=1S/C32H32ClN5O3S/c1-3-21(32(39)40)20-42-30(16-13-22-7-4-5-10-28(22)31-35-36-37-38(31)2)24-8-6-9-27(17-24)41-19-26-15-12-23-11-14-25(33)18-29(23)34-26/h4-12,14-15,17-18,21,30H,3,13,16,19-20H2,1-2H3,(H,39,40)/p-1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory concentration against [3H]-Leukotriene D4 binding to guinea-pig lung membranes was determined				Bioorg Med Chem Lett 2: 1141-1146 (1992) Article DOI: 10.1016/S0960-894X(00)80635-6 BindingDB Entry DOI: 10.7270/Q2D21XJR
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50280687 (CHEMBL280310 | Sodium; 2-[1-[3-(7-chloro-quinolin-...) Show SMILES CCNC(=O)c1ccccc1CCC(SCC(CC)C([O-])=O)c1cccc(OCc2ccc3ccc(Cl)cc3n2)c1 Show InChI InChI=1S/C33H35ClN2O4S/c1-3-22(33(38)39)21-41-31(17-14-23-8-5-6-11-29(23)32(37)35-4-2)25-9-7-10-28(18-25)40-20-27-16-13-24-12-15-26(34)19-30(24)36-27/h5-13,15-16,18-19,22,31H,3-4,14,17,20-21H2,1-2H3,(H,35,37)(H,38,39)/p-1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	0.450	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory concentration against [3H]-Leukotriene D4 binding to guinea-pig lung membranes was determined				Bioorg Med Chem Lett 2: 1141-1146 (1992) Article DOI: 10.1016/S0960-894X(00)80635-6 BindingDB Entry DOI: 10.7270/Q2D21XJR
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50280686 (CHEMBL15120 | Sodium; 2-{3-(2-carbamoyl-phenyl)-1-...) Show SMILES CCC(CSC(CCc1ccccc1C(N)=O)c1cccc(OCc2ccc3ccc(Cl)cc3n2)c1)C([O-])=O Show InChI InChI=1S/C31H31ClN2O4S/c1-2-20(31(36)37)19-39-29(15-12-21-6-3-4-9-27(21)30(33)35)23-7-5-8-26(16-23)38-18-25-14-11-22-10-13-24(32)17-28(22)34-25/h3-11,13-14,16-17,20,29H,2,12,15,18-19H2,1H3,(H2,33,35)(H,36,37)/p-1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	0.470	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory concentration against [3H]-Leukotriene D4 binding to guinea-pig lung membranes was determined				Bioorg Med Chem Lett 2: 1141-1146 (1992) Article DOI: 10.1016/S0960-894X(00)80635-6 BindingDB Entry DOI: 10.7270/Q2D21XJR
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50280693 (CHEMBL15370 | Sodium; 3-[1-[3-(7-chloro-quinolin-2...) Show SMILES CC(CSC(CCc1ccccc1[N+]([O-])=O)c1cccc(OCc2ccc3ccc(Cl)cc3n2)c1)C([O-])=O Show InChI InChI=1S/C29H27ClN2O5S/c1-19(29(33)34)18-38-28(14-11-21-5-2-3-8-27(21)32(35)36)22-6-4-7-25(15-22)37-17-24-13-10-20-9-12-23(30)16-26(20)31-24/h2-10,12-13,15-16,19,28H,11,14,17-18H2,1H3,(H,33,34)/p-1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	0.490	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory concentration against [3H]-Leukotriene D4 binding to guinea-pig lung membranes was determined; experiment 2				Bioorg Med Chem Lett 2: 1141-1146 (1992) Article DOI: 10.1016/S0960-894X(00)80635-6 BindingDB Entry DOI: 10.7270/Q2D21XJR
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50280695 (CHEMBL279630 | Sodium; 2-[1-{3-[2-(7-chloro-quinol...) Show SMILES CCOC(=O)Nc1ccccc1CCC(SCC(CC)C([O-])=O)c1cccc(CCc2ccc3ccc(Cl)cc3n2)c1 Show InChI InChI=1S/C34H37ClN2O4S/c1-3-24(33(38)39)22-42-32(19-15-25-9-5-6-11-30(25)37-34(40)41-4-2)27-10-7-8-23(20-27)12-17-29-18-14-26-13-16-28(35)21-31(26)36-29/h5-11,13-14,16,18,20-21,24,32H,3-4,12,15,17,19,22H2,1-2H3,(H,37,40)(H,38,39)/p-1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory concentration against [3H]-Leukotriene D4 binding to guinea-pig lung membranes was determined; experiment 1				Bioorg Med Chem Lett 2: 1141-1146 (1992) Article DOI: 10.1016/S0960-894X(00)80635-6 BindingDB Entry DOI: 10.7270/Q2D21XJR
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50280696 (CHEMBL274913 | Sodium; (S)-3-{(S)-1-[3-(7-chloro-q...) Show SMILES C[C@H](CS[C@@H](CCc1ccccc1C(C)(C)O)c1cccc(OCc2ccc3ccc(Cl)cc3n2)c1)C([O-])=O Show InChI InChI=1S/C32H34ClNO4S/c1-21(31(35)36)20-39-30(16-13-22-7-4-5-10-28(22)32(2,3)37)24-8-6-9-27(17-24)38-19-26-15-12-23-11-14-25(33)18-29(23)34-26/h4-12,14-15,17-18,21,30,37H,13,16,19-20H2,1-3H3,(H,35,36)/p-1/t21-,30+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory concentration against [3H]-Leukotriene D4 binding to guinea-pig lung membranes was determined; experiment 1				Bioorg Med Chem Lett 2: 1141-1146 (1992) Article DOI: 10.1016/S0960-894X(00)80635-6 BindingDB Entry DOI: 10.7270/Q2D21XJR
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50280699 (3-[1-[3-(7-Chloro-quinolin-2-ylmethoxy)-phenyl]-3-...) Show SMILES CC(CSC(CCc1ccccc1C(=O)N(C)C)c1cccc(OCc2ccc3ccc(Cl)cc3n2)c1)C(O)=O Show InChI InChI=1S/C32H33ClN2O4S/c1-21(32(37)38)20-40-30(16-13-22-7-4-5-10-28(22)31(36)35(2)3)24-8-6-9-27(17-24)39-19-26-15-12-23-11-14-25(33)18-29(23)34-26/h4-12,14-15,17-18,21,30H,13,16,19-20H2,1-3H3,(H,37,38)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	0.520	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory concentration against [3H]-Leukotriene D4 binding to guinea-pig lung membranes was determined				Bioorg Med Chem Lett 2: 1141-1146 (1992) Article DOI: 10.1016/S0960-894X(00)80635-6 BindingDB Entry DOI: 10.7270/Q2D21XJR
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50280698 (CHEMBL274049 | Sodium; 3-[1-[3-(7-chloro-quinolin-...) Show SMILES CS(=O)(=O)Nc1ccccc1CCC(SCCC([O-])=O)c1cccc(OCc2ccc3ccc(Cl)cc3n2)c1 Show InChI InChI=1S/C29H29ClN2O5S2/c1-39(35,36)32-26-8-3-2-5-20(26)11-14-28(38-16-15-29(33)34)22-6-4-7-25(17-22)37-19-24-13-10-21-9-12-23(30)18-27(21)31-24/h2-10,12-13,17-18,28,32H,11,14-16,19H2,1H3,(H,33,34)/p-1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	0.560	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory concentration against [3H]-Leukotriene D4 binding to guinea-pig lung membranes was determined; experiment 1				Bioorg Med Chem Lett 2: 1141-1146 (1992) Article DOI: 10.1016/S0960-894X(00)80635-6 BindingDB Entry DOI: 10.7270/Q2D21XJR
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50280694 (CHEMBL15292 | Sodium; 3-[1-[3-(7-chloro-quinolin-2...) Show SMILES NS(=O)(=O)c1ccccc1CCC(SCCC([O-])=O)c1cccc(OCc2ccc3ccc(Cl)cc3n2)c1 Show InChI InChI=1S/C28H27ClN2O5S2/c29-22-11-8-19-9-12-23(31-25(19)17-22)18-36-24-6-3-5-21(16-24)26(37-15-14-28(32)33)13-10-20-4-1-2-7-27(20)38(30,34)35/h1-9,11-12,16-17,26H,10,13-15,18H2,(H,32,33)(H2,30,34,35)/p-1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory concentration against [3H]-Leukotriene D4 binding to guinea-pig lung membranes was determined; experiment 2				Bioorg Med Chem Lett 2: 1141-1146 (1992) Article DOI: 10.1016/S0960-894X(00)80635-6 BindingDB Entry DOI: 10.7270/Q2D21XJR
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50280709 (CHEMBL15344 | Sodium; 2-[1-[3-(7-chloro-quinolin-2...) Show SMILES CCC(CSC(CCc1ccccc1S(C)(=O)=O)c1cccc(OCc2ccc3ccc(Cl)cc3n2)c1)C([O-])=O Show InChI InChI=1S/C31H32ClNO5S2/c1-3-21(31(34)35)20-39-29(16-13-23-7-4-5-10-30(23)40(2,36)37)24-8-6-9-27(17-24)38-19-26-15-12-22-11-14-25(32)18-28(22)33-26/h4-12,14-15,17-18,21,29H,3,13,16,19-20H2,1-2H3,(H,34,35)/p-1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory concentration against [3H]-Leukotriene D4 binding to guinea-pig lung membranes was determined; experiment 1				Bioorg Med Chem Lett 2: 1141-1146 (1992) Article DOI: 10.1016/S0960-894X(00)80635-6 BindingDB Entry DOI: 10.7270/Q2D21XJR
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50280698 (CHEMBL274049 | Sodium; 3-[1-[3-(7-chloro-quinolin-...) Show SMILES CS(=O)(=O)Nc1ccccc1CCC(SCCC([O-])=O)c1cccc(OCc2ccc3ccc(Cl)cc3n2)c1 Show InChI InChI=1S/C29H29ClN2O5S2/c1-39(35,36)32-26-8-3-2-5-20(26)11-14-28(38-16-15-29(33)34)22-6-4-7-25(17-22)37-19-24-13-10-21-9-12-23(30)18-27(21)31-24/h2-10,12-13,17-18,28,32H,11,14-16,19H2,1H3,(H,33,34)/p-1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory concentration against [3H]-Leukotriene D4 binding to guinea-pig lung membranes was determined; experiment 2				Bioorg Med Chem Lett 2: 1141-1146 (1992) Article DOI: 10.1016/S0960-894X(00)80635-6 BindingDB Entry DOI: 10.7270/Q2D21XJR
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50280709 (CHEMBL15344 | Sodium; 2-[1-[3-(7-chloro-quinolin-2...) Show SMILES CCC(CSC(CCc1ccccc1S(C)(=O)=O)c1cccc(OCc2ccc3ccc(Cl)cc3n2)c1)C([O-])=O Show InChI InChI=1S/C31H32ClNO5S2/c1-3-21(31(34)35)20-39-29(16-13-23-7-4-5-10-30(23)40(2,36)37)24-8-6-9-27(17-24)38-19-26-15-12-22-11-14-25(32)18-28(22)33-26/h4-12,14-15,17-18,21,29H,3,13,16,19-20H2,1-2H3,(H,34,35)/p-1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of Leukotriene D4 induced contraction of guinea-pig trachea was determined				Bioorg Med Chem Lett 2: 1141-1146 (1992) Article DOI: 10.1016/S0960-894X(00)80635-6 BindingDB Entry DOI: 10.7270/Q2D21XJR
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50280695 (CHEMBL279630 | Sodium; 2-[1-{3-[2-(7-chloro-quinol...) Show SMILES CCOC(=O)Nc1ccccc1CCC(SCC(CC)C([O-])=O)c1cccc(CCc2ccc3ccc(Cl)cc3n2)c1 Show InChI InChI=1S/C34H37ClN2O4S/c1-3-24(33(38)39)22-42-32(19-15-25-9-5-6-11-30(25)37-34(40)41-4-2)27-10-7-8-23(20-27)12-17-29-18-14-26-13-16-28(35)21-31(26)36-29/h5-11,13-14,16,18,20-21,24,32H,3-4,12,15,17,19,22H2,1-2H3,(H,37,40)(H,38,39)/p-1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory concentration against [3H]-Leukotriene D4 binding to guinea-pig lung membranes was determined; experiment 2				Bioorg Med Chem Lett 2: 1141-1146 (1992) Article DOI: 10.1016/S0960-894X(00)80635-6 BindingDB Entry DOI: 10.7270/Q2D21XJR
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50280694 (CHEMBL15292 | Sodium; 3-[1-[3-(7-chloro-quinolin-2...) Show SMILES NS(=O)(=O)c1ccccc1CCC(SCCC([O-])=O)c1cccc(OCc2ccc3ccc(Cl)cc3n2)c1 Show InChI InChI=1S/C28H27ClN2O5S2/c29-22-11-8-19-9-12-23(31-25(19)17-22)18-36-24-6-3-5-21(16-24)26(37-15-14-28(32)33)13-10-20-4-1-2-7-27(20)38(30,34)35/h1-9,11-12,16-17,26H,10,13-15,18H2,(H,32,33)(H2,30,34,35)/p-1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory concentration against [3H]-Leukotriene D4 binding to guinea-pig lung membranes was determined; experiment 2				Bioorg Med Chem Lett 2: 1141-1146 (1992) Article DOI: 10.1016/S0960-894X(00)80635-6 BindingDB Entry DOI: 10.7270/Q2D21XJR
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50280689 (CHEMBL278411 | Sodium; 3-{1-[3-(7-chloro-quinolin-...) Show SMILES [O-]C(=O)CCSC(CCc1ccccc1C(=O)N1CCCCC1)c1cccc(OCc2ccc3ccc(Cl)cc3n2)c1 Show InChI InChI=1S/C34H35ClN2O4S/c35-27-14-11-25-12-15-28(36-31(25)22-27)23-41-29-9-6-8-26(21-29)32(42-20-17-33(38)39)16-13-24-7-2-3-10-30(24)34(40)37-18-4-1-5-19-37/h2-3,6-12,14-15,21-22,32H,1,4-5,13,16-20,23H2,(H,38,39)/p-1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory concentration against [3H]-Leukotriene D4 binding to guinea-pig lung membranes was determined				Bioorg Med Chem Lett 2: 1141-1146 (1992) Article DOI: 10.1016/S0960-894X(00)80635-6 BindingDB Entry DOI: 10.7270/Q2D21XJR
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50013919 (3-[{3-[2-(7-Chloro-quinolin-2-yl)-vinyl]-phenyl}-(...) Show SMILES CN(C)C(=O)CCS[C@@H](SCCC(O)=O)c1cccc(\C=C\c2ccc3ccc(Cl)cc3n2)c1 Show InChI InChI=1S/C26H27ClN2O3S2/c1-29(2)24(30)12-14-33-26(34-15-13-25(31)32)20-5-3-4-18(16-20)6-10-22-11-8-19-7-9-21(27)17-23(19)28-22/h3-11,16-17,26H,12-15H2,1-2H3,(H,31,32)/b10-6+/t26-/m0/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	0.770	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description Binding affinity against Cysteinyl leukotriene D4 receptor from guinea pig lung membrane				J Med Chem 33: 2841-5 (1990) BindingDB Entry DOI: 10.7270/Q25M64QQ
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50001285 ((E)-3-((3-(2-(7-chloroquinolin-2-yl)vinyl)phenyl)(...) Show SMILES CN(C)C(=O)CCSC(SCCC(O)=O)c1cccc(\C=C\c2ccc3ccc(Cl)cc3n2)c1 Show InChI InChI=1S/C26H27ClN2O3S2/c1-29(2)24(30)12-14-33-26(34-15-13-25(31)32)20-5-3-4-18(16-20)6-10-22-11-8-19-7-9-21(27)17-23(19)28-22/h3-11,16-17,26H,12-15H2,1-2H3,(H,31,32)/b10-6+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	0.800	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description In vitro inhibition of [3H]LTD4 binding to guinea pig lung membranes				J Med Chem 35: 3832-44 (1992) BindingDB Entry DOI: 10.7270/Q2TQ625N
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50280703 (CHEMBL278210 | Sodium; 2-{1-[3-(7-chloro-quinolin-...) Show SMILES CCC(CSC(CCc1ccccc1-c1nnn[nH]1)c1cccc(OCc2ccc3ccc(Cl)cc3n2)c1)C([O-])=O Show InChI InChI=1S/C31H30ClN5O3S/c1-2-20(31(38)39)19-41-29(15-12-21-6-3-4-9-27(21)30-34-36-37-35-30)23-7-5-8-26(16-23)40-18-25-14-11-22-10-13-24(32)17-28(22)33-25/h3-11,13-14,16-17,20,29H,2,12,15,18-19H2,1H3,(H,38,39)(H,34,35,36,37)/p-1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	0.800	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory concentration against [3H]-Leukotriene D4 binding to guinea-pig lung membranes was determined; experiment 1				Bioorg Med Chem Lett 2: 1141-1146 (1992) Article DOI: 10.1016/S0960-894X(00)80635-6 BindingDB Entry DOI: 10.7270/Q2D21XJR
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50280696 (CHEMBL274913 | Sodium; (S)-3-{(S)-1-[3-(7-chloro-q...) Show SMILES C[C@H](CS[C@@H](CCc1ccccc1C(C)(C)O)c1cccc(OCc2ccc3ccc(Cl)cc3n2)c1)C([O-])=O Show InChI InChI=1S/C32H34ClNO4S/c1-21(31(35)36)20-39-30(16-13-22-7-4-5-10-28(22)32(2,3)37)24-8-6-9-27(17-24)38-19-26-15-12-23-11-14-25(33)18-29(23)34-26/h4-12,14-15,17-18,21,30,37H,13,16,19-20H2,1-3H3,(H,35,36)/p-1/t21-,30+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	0.850	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory concentration against [3H]-Leukotriene D4 binding to guinea-pig lung membranes was determined; experiment 1				Bioorg Med Chem Lett 2: 1141-1146 (1992) Article DOI: 10.1016/S0960-894X(00)80635-6 BindingDB Entry DOI: 10.7270/Q2D21XJR
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50280714 ((S)-2-{(S)-1-{3-[(E)-2-(7-Chloro-quinolin-2-yl)-vi...) Show SMILES CCC[C@H](CS[C@@H](CCc1ccccc1C(C)(C)O)c1cccc(\C=C\c2ccc3ccc(Cl)cc3n2)c1)C(O)=O Show InChI InChI=1S/C35H38ClNO3S/c1-4-8-28(34(38)39)23-41-33(20-16-25-10-5-6-12-31(25)35(2,3)40)27-11-7-9-24(21-27)13-18-30-19-15-26-14-17-29(36)22-32(26)37-30/h5-7,9-15,17-19,21-22,28,33,40H,4,8,16,20,23H2,1-3H3,(H,38,39)/b18-13+/t28-,33+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	0.900	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory concentration against [3H]-Leukotriene D4 binding to guinea-pig lung membranes was determined				Bioorg Med Chem Lett 2: 1141-1146 (1992) Article DOI: 10.1016/S0960-894X(00)80635-6 BindingDB Entry DOI: 10.7270/Q2D21XJR
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50280702 (3-[1-[3-(7-Chloro-quinolin-2-ylmethoxy)-phenyl]-3-...) Show SMILES CN(C)C(=O)c1ccccc1CCC(SCCC(O)=O)c1cccc(OCc2ccc3ccc(Cl)cc3n2)c1 Show InChI InChI=1S/C31H31ClN2O4S/c1-34(2)31(37)27-9-4-3-6-21(27)12-15-29(39-17-16-30(35)36)23-7-5-8-26(18-23)38-20-25-14-11-22-10-13-24(32)19-28(22)33-25/h3-11,13-14,18-19,29H,12,15-17,20H2,1-2H3,(H,35,36)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	0.950	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory concentration against [3H]-Leukotriene D4 binding to guinea-pig lung membranes was determined				Bioorg Med Chem Lett 2: 1141-1146 (1992) Article DOI: 10.1016/S0960-894X(00)80635-6 BindingDB Entry DOI: 10.7270/Q2D21XJR
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50280715 (CHEMBL15513 | Sodium; 3-[1-[3-(7-chloro-quinolin-2...) Show SMILES CN(C)C(=O)c1ccccc1CCC(SCCC([O-])=O)c1cccc(OCc2ccc3ccc(Cl)cc3n2)c1 Show InChI InChI=1S/C31H31ClN2O4S/c1-34(2)31(37)27-9-4-3-6-21(27)12-15-29(39-17-16-30(35)36)23-7-5-8-26(18-23)38-20-25-14-11-22-10-13-24(32)19-28(22)33-25/h3-11,13-14,18-19,29H,12,15-17,20H2,1-2H3,(H,35,36)/p-1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	0.950	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory concentration against [3H]-Leukotriene D4 binding to guinea-pig lung membranes was determined				Bioorg Med Chem Lett 2: 1141-1146 (1992) Article DOI: 10.1016/S0960-894X(00)80635-6 BindingDB Entry DOI: 10.7270/Q2D21XJR
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50283939 ((S)-3-{(S)-1-{3-[(E)-2-(7-Chloro-quinolin-2-yl)-vi...) Show SMILES C[C@H](CS[C@@H](CCc1ccccc1CC(C)(C)O)c1cccc(\C=C\c2ccc3ccc(Cl)cc3n2)c1)C(O)=O Show InChI InChI=1S/C34H36ClNO3S/c1-23(33(37)38)22-40-32(18-14-25-8-4-5-9-28(25)21-34(2,3)39)27-10-6-7-24(19-27)11-16-30-17-13-26-12-15-29(35)20-31(26)36-30/h4-13,15-17,19-20,23,32,39H,14,18,21-22H2,1-3H3,(H,37,38)/b16-11+/t23-,32+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against binding of [3H]-LTD4 to Cysteinyl leukotriene D4 receptor in guinea pig lung membranes				Bioorg Med Chem Lett 4: 463-468 (1994) Article DOI: 10.1016/0960-894X(94)80017-0 BindingDB Entry DOI: 10.7270/Q2M908N4
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50280708 (CHEMBL416161 | Sodium; 2-[1-{3-[2-(7-chloro-quinol...) Show SMILES CCC(CSC(CCc1ccccc1C#N)c1cccc(CCc2ccc3ccc(Cl)cc3n2)c1)C([O-])=O Show InChI InChI=1S/C32H31ClN2O2S/c1-2-23(32(36)37)21-38-31(17-13-24-7-3-4-8-27(24)20-34)26-9-5-6-22(18-26)10-15-29-16-12-25-11-14-28(33)19-30(25)35-29/h3-9,11-12,14,16,18-19,23,31H,2,10,13,15,17,21H2,1H3,(H,36,37)/p-1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory concentration against [3H]-Leukotriene D4 binding to guinea-pig lung membranes was determined				Bioorg Med Chem Lett 2: 1141-1146 (1992) Article DOI: 10.1016/S0960-894X(00)80635-6 BindingDB Entry DOI: 10.7270/Q2D21XJR
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50280707 (3-(1-{3-[(E)-2-(7-Chloro-quinolin-2-yl)-vinyl]-phe...) Show SMILES CC(CCC(SCCC(O)=O)c1cccc(\C=C\c2ccc3ccc(Cl)cc3n2)c1)CC(=O)N(C)C Show InChI InChI=1S/C29H33ClN2O3S/c1-20(17-28(33)32(2)3)7-14-27(36-16-15-29(34)35)23-6-4-5-21(18-23)8-12-25-13-10-22-9-11-24(30)19-26(22)31-25/h4-6,8-13,18-20,27H,7,14-17H2,1-3H3,(H,34,35)/b12-8+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory concentration against [3H]-Leukotriene D4 binding to guinea-pig lung membranes was determined				Bioorg Med Chem Lett 2: 1141-1146 (1992) Article DOI: 10.1016/S0960-894X(00)80635-6 BindingDB Entry DOI: 10.7270/Q2D21XJR
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50280688 (CHEMBL429975 | Sodium; 2-{1-[3-(7-chloro-quinolin-...) Show SMILES CCC(CSC(CCc1ccccc1C(=O)NS(=O)(=O)c1ccccc1C)c1cccc(OCc2ccc3ccc(Cl)cc3n2)c1)C([O-])=O Show InChI InChI=1S/C38H37ClN2O6S2/c1-3-26(38(43)44)24-48-35(29-11-8-12-32(21-29)47-23-31-19-16-28-15-18-30(39)22-34(28)40-31)20-17-27-10-5-6-13-33(27)37(42)41-49(45,46)36-14-7-4-9-25(36)2/h4-16,18-19,21-22,26,35H,3,17,20,23-24H2,1-2H3,(H,41,42)(H,43,44)/p-1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory concentration against [3H]-Leukotriene D4 binding to guinea-pig lung membranes was determined; experiment 1				Bioorg Med Chem Lett 2: 1141-1146 (1992) Article DOI: 10.1016/S0960-894X(00)80635-6 BindingDB Entry DOI: 10.7270/Q2D21XJR
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50280710 (2-[3-[3-(7-Chloro-quinolin-2-ylmethoxy)-phenyl]-3-...) Show SMILES CN(C)C(=O)CCSC(CCc1ccccc1C(O)=O)c1cccc(OCc2ccc3ccc(Cl)cc3n2)c1 Show InChI InChI=1S/C31H31ClN2O4S/c1-34(2)30(35)16-17-39-29(15-12-21-6-3-4-9-27(21)31(36)37)23-7-5-8-26(18-23)38-20-25-14-11-22-10-13-24(32)19-28(22)33-25/h3-11,13-14,18-19,29H,12,15-17,20H2,1-2H3,(H,36,37)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	1.90	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory concentration against [3H]-Leukotriene D4 binding to guinea-pig lung membranes was determined				Bioorg Med Chem Lett 2: 1141-1146 (1992) Article DOI: 10.1016/S0960-894X(00)80635-6 BindingDB Entry DOI: 10.7270/Q2D21XJR
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50280697 (CHEMBL280260 | Sodium; 2-{3-(2-carboxy-phenyl)-1-[...) Show SMILES CCC(CSC(CCc1ccccc1C(O)=O)c1cccc(OCc2ccc3ccc(Cl)cc3n2)c1)C([O-])=O Show InChI InChI=1S/C31H30ClNO5S/c1-2-20(30(34)35)19-39-29(15-12-21-6-3-4-9-27(21)31(36)37)23-7-5-8-26(16-23)38-18-25-14-11-22-10-13-24(32)17-28(22)33-25/h3-11,13-14,16-17,20,29H,2,12,15,18-19H2,1H3,(H,34,35)(H,36,37)/p-1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory concentration of the compound against [3H]-Leukotriene D4 binding to guinea-pig lung membranes was determined (Experiment 2)				Bioorg Med Chem Lett 2: 1141-1146 (1992) Article DOI: 10.1016/S0960-894X(00)80635-6 BindingDB Entry DOI: 10.7270/Q2D21XJR
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50283938 ((S)-3-[(S)-1-{3-[(E)-2-(7-Chloro-quinolin-2-yl)-vi...) Show SMILES C[C@H](CS[C@@H](CCc1ccccc1C=O)c1cccc(\C=C\c2ccc3ccc(Cl)cc3n2)c1)C(O)=O Show InChI InChI=1S/C31H28ClNO3S/c1-21(31(35)36)20-37-30(16-12-23-6-2-3-7-26(23)19-34)25-8-4-5-22(17-25)9-14-28-15-11-24-10-13-27(32)18-29(24)33-28/h2-11,13-15,17-19,21,30H,12,16,20H2,1H3,(H,35,36)/b14-9+/t21-,30+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against binding of [3H]-LTD4 to Cysteinyl leukotriene D4 receptor in guinea pig lung membranes				Bioorg Med Chem Lett 4: 463-468 (1994) Article DOI: 10.1016/0960-894X(94)80017-0 BindingDB Entry DOI: 10.7270/Q2M908N4
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50280705 (CHEMBL15306 | Sodium; (S)-3-{(R)-1-[3-(7-chloro-qu...) Show SMILES C[C@H](CS[C@H](CCc1ccccc1C(C)(C)O)c1cccc(OCc2ccc3ccc(Cl)cc3n2)c1)C([O-])=O Show InChI InChI=1S/C32H34ClNO4S/c1-21(31(35)36)20-39-30(16-13-22-7-4-5-10-28(22)32(2,3)37)24-8-6-9-27(17-24)38-19-26-15-12-23-11-14-25(33)18-29(23)34-26/h4-12,14-15,17-18,21,30,37H,13,16,19-20H2,1-3H3,(H,35,36)/p-1/t21-,30-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory concentration against [3H]-Leukotriene D4 binding to guinea-pig lung membranes was determined; experiment 2				Bioorg Med Chem Lett 2: 1141-1146 (1992) Article DOI: 10.1016/S0960-894X(00)80635-6 BindingDB Entry DOI: 10.7270/Q2D21XJR
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50280697 (CHEMBL280260 | Sodium; 2-{3-(2-carboxy-phenyl)-1-[...) Show SMILES CCC(CSC(CCc1ccccc1C(O)=O)c1cccc(OCc2ccc3ccc(Cl)cc3n2)c1)C([O-])=O Show InChI InChI=1S/C31H30ClNO5S/c1-2-20(30(34)35)19-39-29(15-12-21-6-3-4-9-27(21)31(36)37)23-7-5-8-26(16-23)38-18-25-14-11-22-10-13-24(32)17-28(22)33-25/h3-11,13-14,16-17,20,29H,2,12,15,18-19H2,1H3,(H,34,35)(H,36,37)/p-1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory concentration against [3H]-Leukotriene D4 binding to guinea-pig lung membranes was determined; experiment 1				Bioorg Med Chem Lett 2: 1141-1146 (1992) Article DOI: 10.1016/S0960-894X(00)80635-6 BindingDB Entry DOI: 10.7270/Q2D21XJR
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50283936 ((S)-3-[(S)-1-{3-[(E)-2-(7-Chloro-quinolin-2-yl)-vi...) Show SMILES C[C@H](CS[C@@H](CCc1cccc(CO)c1)c1cccc(\C=C\c2ccc3ccc(Cl)cc3n2)c1)C(O)=O Show InChI InChI=1S/C31H30ClNO3S/c1-21(31(35)36)20-37-30(15-9-22-4-2-6-24(16-22)19-34)26-7-3-5-23(17-26)8-13-28-14-11-25-10-12-27(32)18-29(25)33-28/h2-8,10-14,16-18,21,30,34H,9,15,19-20H2,1H3,(H,35,36)/b13-8+/t21-,30+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	2.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against binding of [3H]-LTD4 to Cysteinyl leukotriene D4 receptor in guinea pig lung membranes				Bioorg Med Chem Lett 4: 463-468 (1994) Article DOI: 10.1016/0960-894X(94)80017-0 BindingDB Entry DOI: 10.7270/Q2M908N4
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50001293 (3-[{3-[2-(7-Chloro-quinolin-2-yl)-vinyl]-phenyl}-(...) Show SMILES OC(=O)CCSC(SCCC(=O)N1CCOCC1)c1cccc(\C=C\c2ccc3ccc(Cl)cc3n2)c1 Show InChI InChI=1S/C28H29ClN2O4S2/c29-23-7-5-21-6-9-24(30-25(21)19-23)8-4-20-2-1-3-22(18-20)28(37-17-11-27(33)34)36-16-10-26(32)31-12-14-35-15-13-31/h1-9,18-19,28H,10-17H2,(H,33,34)/b8-4+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	2.20	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description In vitro inhibition of [3H]LTD4 binding to guinea pig lung membranes				J Med Chem 35: 3832-44 (1992) BindingDB Entry DOI: 10.7270/Q2TQ625N
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50283943 ((S)-3-{(S)-1-{3-[(E)-2-(7-Chloro-quinolin-2-yl)-vi...) Show SMILES C[C@H](CS[C@@H](CCc1ccccc1C(C)(C)O)c1cccc(\C=C\c2ccc3ccc(Cl)cc3n2)c1)C(O)=O Show InChI InChI=1S/C33H34ClNO3S/c1-22(32(36)37)21-39-31(18-14-24-8-4-5-10-29(24)33(2,3)38)26-9-6-7-23(19-26)11-16-28-17-13-25-12-15-27(34)20-30(25)35-28/h4-13,15-17,19-20,22,31,38H,14,18,21H2,1-3H3,(H,36,37)/b16-11+/t22-,31+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	2.70	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against binding of [3H]-LTD4 to Cysteinyl leukotriene D4 receptor in guinea pig lung membranes				Bioorg Med Chem Lett 4: 463-468 (1994) Article DOI: 10.1016/0960-894X(94)80017-0 BindingDB Entry DOI: 10.7270/Q2M908N4
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50283945 ((S)-3-((S)-3-(2-Acetyl-phenyl)-1-{3-[(E)-2-(7-chlo...) Show SMILES C[C@H](CS[C@@H](CCc1ccccc1C(C)=O)c1cccc(C=Cc2ccc3ccc(Cl)cc3n2)c1)C(O)=O |w:21.21| Show InChI InChI=1S/C32H30ClNO3S/c1-21(32(36)37)20-38-31(17-13-24-7-3-4-9-29(24)22(2)35)26-8-5-6-23(18-26)10-15-28-16-12-25-11-14-27(33)19-30(25)34-28/h3-12,14-16,18-19,21,31H,13,17,20H2,1-2H3,(H,36,37)/t21-,31+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against binding of [3H]-LTD4 to Cysteinyl leukotriene D4 receptor in guinea pig lung membranes				Bioorg Med Chem Lett 4: 463-468 (1994) Article DOI: 10.1016/0960-894X(94)80017-0 BindingDB Entry DOI: 10.7270/Q2M908N4
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1/2 (Homo sapiens (Human))	BDBM50230047 (CHEMBL127877) Show SMILES OC(=O)CCSC(SCCC(O)=O)c1cccc(\C=C\c2ccc3ccc(Cl)cc3n2)c1 Show InChI InChI=1S/C24H22ClNO4S2/c25-19-7-5-17-6-9-20(26-21(17)15-19)8-4-16-2-1-3-18(14-16)24(31-12-10-22(27)28)32-13-11-23(29)30/h1-9,14-15,24H,10-13H2,(H,27,28)(H,29,30)/b8-4+	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description Inhibition of human carbonic anhydrase II				J Med Chem 35: 3832-44 (1992) BindingDB Entry DOI: 10.7270/Q2TQ625N
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50283941 ((S)-3-[(S)-1-{3-[(E)-2-(7-Chloro-quinolin-2-yl)-vi...) Show SMILES C[C@H](CS[C@@H](CCc1ccccc1CO)c1cccc(\C=C\c2ccc3ccc(Cl)cc3n2)c1)C(O)=O Show InChI InChI=1S/C31H30ClNO3S/c1-21(31(35)36)20-37-30(16-12-23-6-2-3-7-26(23)19-34)25-8-4-5-22(17-25)9-14-28-15-11-24-10-13-27(32)18-29(24)33-28/h2-11,13-15,17-18,21,30,34H,12,16,19-20H2,1H3,(H,35,36)/b14-9+/t21-,30+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	3.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against binding of [3H]-LTD4 to Cysteinyl leukotriene D4 receptor in guinea pig lung membranes				Bioorg Med Chem Lett 4: 463-468 (1994) Article DOI: 10.1016/0960-894X(94)80017-0 BindingDB Entry DOI: 10.7270/Q2M908N4
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (Homo sapiens (Human))	BDBM50013919 (3-[{3-[2-(7-Chloro-quinolin-2-yl)-vinyl]-phenyl}-(...) Show SMILES CN(C)C(=O)CCS[C@@H](SCCC(O)=O)c1cccc(\C=C\c2ccc3ccc(Cl)cc3n2)c1 Show InChI InChI=1S/C26H27ClN2O3S2/c1-29(2)24(30)12-14-33-26(34-15-13-25(31)32)20-5-3-4-18(16-20)6-10-22-11-8-19-7-9-21(27)17-23(19)28-22/h3-11,16-17,26H,12-15H2,1-2H3,(H,31,32)/b10-6+/t26-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.10	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description Binding affinity against Cysteinyl leukotriene D4 receptor from guinea pig lung membrane				J Med Chem 33: 2841-5 (1990) BindingDB Entry DOI: 10.7270/Q25M64QQ
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50013920 (3-[(R)-{3-[(E)-2-(7-Chloro-quinolin-2-yl)-vinyl]-p...) Show SMILES CN(C)C(=O)CCS[C@H](SCCC(O)=O)c1cccc(\C=C\c2ccc3ccc(Cl)cc3n2)c1 Show InChI InChI=1S/C26H27ClN2O3S2/c1-29(2)24(30)12-14-33-26(34-15-13-25(31)32)20-5-3-4-18(16-20)6-10-22-11-8-19-7-9-21(27)17-23(19)28-22/h3-11,16-17,26H,12-15H2,1-2H3,(H,31,32)/b10-6+/t26-/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.20	n/a	n/a	n/a	n/a	n/a	n/a
Merck Frosst Centre for Therapeutic Research Curated by ChEMBL					Assay Description Binding affinity against Cysteinyl leukotriene D4 receptor from guinea pig lung membrane				J Med Chem 33: 2841-5 (1990) BindingDB Entry DOI: 10.7270/Q25M64QQ
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50280691 (3-{1-[3-(7-Chloro-quinolin-2-ylmethoxy)-phenyl]-3-...) Show SMILES CC(CSC(CCc1ccccc1C(=O)N(C)CO)c1cccc(OCc2ccc3ccc(Cl)cc3n2)c1)C(O)=O Show InChI InChI=1S/C32H33ClN2O5S/c1-21(32(38)39)19-41-30(15-12-22-6-3-4-9-28(22)31(37)35(2)20-36)24-7-5-8-27(16-24)40-18-26-14-11-23-10-13-25(33)17-29(23)34-26/h3-11,13-14,16-17,21,30,36H,12,15,18-20H2,1-2H3,(H,38,39)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	3.60	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory concentration against [3H]-Leukotriene D4 binding to guinea-pig lung membranes was determined				Bioorg Med Chem Lett 2: 1141-1146 (1992) Article DOI: 10.1016/S0960-894X(00)80635-6 BindingDB Entry DOI: 10.7270/Q2D21XJR
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50283942 (2-((S)-3-((S)-2-Carboxy-propylsulfanyl)-3-{3-[(E)-...) Show SMILES CCOC(=O)c1ccccc1CC[C@H](SC[C@@H](C)C(O)=O)c1cccc(\C=C\c2ccc3ccc(Cl)cc3n2)c1 Show InChI InChI=1S/C33H32ClNO4S/c1-3-39-33(38)29-10-5-4-8-24(29)14-18-31(40-21-22(2)32(36)37)26-9-6-7-23(19-26)11-16-28-17-13-25-12-15-27(34)20-30(25)35-28/h4-13,15-17,19-20,22,31H,3,14,18,21H2,1-2H3,(H,36,37)/b16-11+/t22-,31+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	3.70	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against binding of [3H]-LTD4 to Cysteinyl leukotriene D4 receptor in guinea pig lung membranes				Bioorg Med Chem Lett 4: 463-468 (1994) Article DOI: 10.1016/0960-894X(94)80017-0 BindingDB Entry DOI: 10.7270/Q2M908N4
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50283940 ((S)-3-[(S)-1-{3-[(E)-2-(7-Chloro-quinolin-2-yl)-vi...) Show SMILES CCC(=O)c1ccccc1CC[C@H](SC[C@@H](C)C(O)=O)c1cccc(C=Cc2ccc3ccc(Cl)cc3n2)c1 |w:25.25| Show InChI InChI=1S/C33H32ClNO3S/c1-3-31(36)29-10-5-4-8-24(29)14-18-32(39-21-22(2)33(37)38)26-9-6-7-23(19-26)11-16-28-17-13-25-12-15-27(34)20-30(25)35-28/h4-13,15-17,19-20,22,32H,3,14,18,21H2,1-2H3,(H,37,38)/t22-,32+/m1/s1	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	3.70	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against binding of [3H]-LTD4 to Cysteinyl leukotriene D4 receptor in guinea pig lung membranes				Bioorg Med Chem Lett 4: 463-468 (1994) Article DOI: 10.1016/0960-894X(94)80017-0 BindingDB Entry DOI: 10.7270/Q2M908N4
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50001285 ((E)-3-((3-(2-(7-chloroquinolin-2-yl)vinyl)phenyl)(...) Show SMILES CN(C)C(=O)CCSC(SCCC(O)=O)c1cccc(\C=C\c2ccc3ccc(Cl)cc3n2)c1 Show InChI InChI=1S/C26H27ClN2O3S2/c1-29(2)24(30)12-14-33-26(34-15-13-25(31)32)20-5-3-4-18(16-20)6-10-22-11-8-19-7-9-21(27)17-23(19)28-22/h3-11,16-17,26H,12-15H2,1-2H3,(H,31,32)/b10-6+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Patents Similars	Article	n/a	n/a	3.90	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory concentration against [3H]-Leukotriene D4 binding to guinea-pig lung membranes was determined; experiment 2				Bioorg Med Chem Lett 2: 1141-1146 (1992) Article DOI: 10.1016/S0960-894X(00)80635-6 BindingDB Entry DOI: 10.7270/Q2D21XJR
					More data for this Ligand-Target Pair

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