Compile Data Set for Download or QSAR

Found 98 hits with Last Name = 'chino' and Initial = 'y'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM50315427 ((1S)-1,5-Anhydro-1-[4-chloro-3-[4-(methylsulfanyl)...) Show SMILES CSc1ccc(Cc2cc(ccc2Cl)[C@@H]2S[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)cc1 |r| Show InChI InChI=1S/C20H23ClO4S2/c1-26-14-5-2-11(3-6-14)8-13-9-12(4-7-15(13)21)20-19(25)18(24)17(23)16(10-22)27-20/h2-7,9,16-20,22-25H,8,10H2,1H3/t16-,17-,18+,19-,20+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of human SGLT2 expressed in CHOK1 cells assessed as inhibition of glucose uptake				J Med Chem 53: 3247-61 (2010) Article DOI: 10.1021/jm901893x BindingDB Entry DOI: 10.7270/Q2KH0NG6
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM50315431 ((1S)-1,5-Anhydro-1-[4-chloro-3-(4-methylbenzyl)phe...) Show SMILES Cc1ccc(Cc2cc(ccc2Cl)[C@@H]2S[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)cc1 |r| Show InChI InChI=1S/C20H23ClO4S/c1-11-2-4-12(5-3-11)8-14-9-13(6-7-15(14)21)20-19(25)18(24)17(23)16(10-22)26-20/h2-7,9,16-20,22-25H,8,10H2,1H3/t16-,17-,18+,19-,20+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of human SGLT2 expressed in CHOK1 cells assessed as inhibition of glucose uptake				J Med Chem 53: 3247-61 (2010) Article DOI: 10.1021/jm901893x BindingDB Entry DOI: 10.7270/Q2KH0NG6
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM50315423 ((1S)-1,5-Anhydro-1-[4-chloro-5-(4-ethylbenzyl)-2-m...) Show SMILES CCc1ccc(Cc2cc([C@@H]3S[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)c(OC)cc2Cl)cc1 |r| Show InChI InChI=1S/C22H27ClO5S/c1-3-12-4-6-13(7-5-12)8-14-9-15(17(28-2)10-16(14)23)22-21(27)20(26)19(25)18(11-24)29-22/h4-7,9-10,18-22,24-27H,3,8,11H2,1-2H3/t18-,19-,20+,21-,22+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of human SGLT2 expressed in CHOK1 cells assessed as inhibition of glucose uptake				J Med Chem 53: 3247-61 (2010) Article DOI: 10.1021/jm901893x BindingDB Entry DOI: 10.7270/Q2KH0NG6
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM50315432 ((1S)-1,5-Anhydro-1-[4-chloro-3-(4-methoxybenzyl)ph...) Show SMILES COc1ccc(Cc2cc(ccc2Cl)[C@@H]2S[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)cc1 |r| Show InChI InChI=1S/C20H23ClO5S/c1-26-14-5-2-11(3-6-14)8-13-9-12(4-7-15(13)21)20-19(25)18(24)17(23)16(10-22)27-20/h2-7,9,16-20,22-25H,8,10H2,1H3/t16-,17-,18+,19-,20+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.70	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of human SGLT2 expressed in CHOK1 cells assessed as inhibition of glucose uptake				J Med Chem 53: 3247-61 (2010) Article DOI: 10.1021/jm901893x BindingDB Entry DOI: 10.7270/Q2KH0NG6
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM50315425 ((1S)-1,5-Anhydro-1-[5-(4-ethylbenzyl)-2-methoxy-4-...) Show SMILES CCc1ccc(Cc2cc([C@@H]3S[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)c(OC)cc2C)cc1 |r| Show InChI InChI=1S/C23H30O5S/c1-4-14-5-7-15(8-6-14)10-16-11-17(18(28-3)9-13(16)2)23-22(27)21(26)20(25)19(12-24)29-23/h5-9,11,19-27H,4,10,12H2,1-3H3/t19-,20-,21+,22-,23+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.70	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of human SGLT2 expressed in CHOK1 cells assessed as inhibition of glucose uptake				J Med Chem 53: 3247-61 (2010) Article DOI: 10.1021/jm901893x BindingDB Entry DOI: 10.7270/Q2KH0NG6
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM50315436 ((1S)-1,5-Anhydro-1-[4-chloro-3-(4-ethoxybenzyl)phe...) Show SMILES CCOc1ccc(Cc2cc(ccc2Cl)[C@@H]2S[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)cc1 |r| Show InChI InChI=1S/C21H25ClO5S/c1-2-27-15-6-3-12(4-7-15)9-14-10-13(5-8-16(14)22)21-20(26)19(25)18(24)17(11-23)28-21/h3-8,10,17-21,23-26H,2,9,11H2,1H3/t17-,18-,19+,20-,21+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.80	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of human SGLT2 expressed in CHOK1 cells assessed as inhibition of glucose uptake				J Med Chem 53: 3247-61 (2010) Article DOI: 10.1021/jm901893x BindingDB Entry DOI: 10.7270/Q2KH0NG6
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM50315430 ((1S)-1,5-Anhydro-1-[4-chloro-3-(4-ethylbenzyl)phen...) Show SMILES CCc1ccc(Cc2cc(ccc2Cl)[C@@H]2S[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)cc1 |r| Show InChI InChI=1S/C21H25ClO4S/c1-2-12-3-5-13(6-4-12)9-15-10-14(7-8-16(15)22)21-20(26)19(25)18(24)17(11-23)27-21/h3-8,10,17-21,23-26H,2,9,11H2,1H3/t17-,18-,19+,20-,21+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.80	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of human SGLT2 expressed in CHOK1 cells assessed as inhibition of glucose uptake				J Med Chem 53: 3247-61 (2010) Article DOI: 10.1021/jm901893x BindingDB Entry DOI: 10.7270/Q2KH0NG6
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM50315426 ((1S)-1,5-Anhydro-1-[5-(4-ethoxybenzyl)-2-methoxy-4...) Show SMILES CCOc1ccc(Cc2cc([C@@H]3S[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)c(OC)cc2C)cc1 |r| Show InChI InChI=1S/C23H30O6S/c1-4-29-16-7-5-14(6-8-16)10-15-11-17(18(28-3)9-13(15)2)23-22(27)21(26)20(25)19(12-24)30-23/h5-9,11,19-27H,4,10,12H2,1-3H3/t19-,20-,21+,22-,23+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.30	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of human SGLT2 expressed in CHOK1 cells assessed as inhibition of glucose uptake				J Med Chem 53: 3247-61 (2010) Article DOI: 10.1021/jm901893x BindingDB Entry DOI: 10.7270/Q2KH0NG6
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM50315418 ((1S)-1,5-Anhydro-1-[3-(4-ethoxybenzyl)-4-methylphe...) Show SMILES CCOc1ccc(Cc2cc(ccc2C)[C@@H]2S[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)cc1 |r| Show InChI InChI=1S/C22H28O5S/c1-3-27-17-8-5-14(6-9-17)10-16-11-15(7-4-13(16)2)22-21(26)20(25)19(24)18(12-23)28-22/h4-9,11,18-26H,3,10,12H2,1-2H3/t18-,19-,20+,21-,22+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.30	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of human SGLT2 expressed in CHOK1 cells assessed as inhibition of glucose uptake				J Med Chem 53: 3247-61 (2010) Article DOI: 10.1021/jm901893x BindingDB Entry DOI: 10.7270/Q2KH0NG6
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM50315424 ((1S)-1,5-Anhydro-1-[2-methoxy-4-methyl-5-[4-(propa...) Show SMILES COc1cc(C)c(Cc2ccc(cc2)C(C)C)cc1[C@@H]1S[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O |r| Show InChI InChI=1S/C24H32O5S/c1-13(2)16-7-5-15(6-8-16)10-17-11-18(19(29-4)9-14(17)3)24-23(28)22(27)21(26)20(12-25)30-24/h5-9,11,13,20-28H,10,12H2,1-4H3/t20-,21-,22+,23-,24+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.70	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of human SGLT2 expressed in CHOK1 cells assessed as inhibition of glucose uptake				J Med Chem 53: 3247-61 (2010) Article DOI: 10.1021/jm901893x BindingDB Entry DOI: 10.7270/Q2KH0NG6
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human))	BDBM363976 (N-[(exo)-8-(tert-Butylcarbamoyl)methyl-8-azabicycl...) Show SMILES CC(C)(C)NC(=O)CN1[C@H]2CC[C@@H]1C[C@@H](CNC(=O)c1coc3ccccc13)C2 |r,THB:7:8:13.14.28:10.11| Show InChI InChI=1S/C23H31N3O3/c1-23(2,3)25-21(27)13-26-16-8-9-17(26)11-15(10-16)12-24-22(28)19-14-29-20-7-5-4-6-18(19)20/h4-7,14-17H,8-13H2,1-3H3,(H,24,28)(H,25,27)/t15-,16-,17+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company					Assay Description The HEK293 cells having human Cav3.2 stably expressed therein were cultured at 37° C. in Alpha-MEM, to which 10% (v/v) fetal bovine serum (FBS), peni...				J Med Chem 49: 2440-55 (2006) BindingDB Entry DOI: 10.7270/Q2G73H2M
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM50315429 ((1S)-1,5-Anhydro-1-[4-chloro-3-[4-(propan-2-yl)ben...) Show SMILES CC(C)c1ccc(Cc2cc(ccc2Cl)[C@@H]2S[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)cc1 |r| Show InChI InChI=1S/C22H27ClO4S/c1-12(2)14-5-3-13(4-6-14)9-16-10-15(7-8-17(16)23)22-21(27)20(26)19(25)18(11-24)28-22/h3-8,10,12,18-22,24-27H,9,11H2,1-2H3/t18-,19-,20+,21-,22+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of human SGLT2 expressed in CHOK1 cells assessed as inhibition of glucose uptake				J Med Chem 53: 3247-61 (2010) Article DOI: 10.1021/jm901893x BindingDB Entry DOI: 10.7270/Q2KH0NG6
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM50315419 ((1S)-1,5-Anhydro-1-[3-(4-ethoxybenzyl)-4-fluorophe...) Show SMILES CCOc1ccc(Cc2cc(ccc2F)[C@@H]2S[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)cc1 |r| Show InChI InChI=1S/C21H25FO5S/c1-2-27-15-6-3-12(4-7-15)9-14-10-13(5-8-16(14)22)21-20(26)19(25)18(24)17(11-23)28-21/h3-8,10,17-21,23-26H,2,9,11H2,1H3/t17-,18-,19+,20-,21+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	9.40	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of human SGLT2 expressed in CHOK1 cells assessed as inhibition of glucose uptake				J Med Chem 53: 3247-61 (2010) Article DOI: 10.1021/jm901893x BindingDB Entry DOI: 10.7270/Q2KH0NG6
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human))	BDBM364007 (US9856250, 84) Show SMILES CCC1=C(C2C=CC=CC2O1)C(=O)NC[C@H]1C[C@@H]2CC[C@H](C1)N2CC(=O)NC(C)(C)C |r,c:5,7,t:2,THB:23:22:21.15.16:18.19| Show InChI InChI=1S/C25H37N3O3/c1-5-20-23(19-8-6-7-9-21(19)31-20)24(30)26-14-16-12-17-10-11-18(13-16)28(17)15-22(29)27-25(2,3)4/h6-9,16-19,21H,5,10-15H2,1-4H3,(H,26,30)(H,27,29)/t16-,17-,18+,19?,21?	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company					Assay Description The HEK293 cells having human Cav3.2 stably expressed therein were cultured at 37° C. in Alpha-MEM, to which 10% (v/v) fetal bovine serum (FBS), peni...				J Med Chem 49: 2440-55 (2006) BindingDB Entry DOI: 10.7270/Q2G73H2M
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM50315433 ((1S)-1,5-Anhydro-1-[2,4-dimethoxy-5-(4-ethoxybenzy...) Show SMILES CCOc1ccc(Cc2cc([C@@H]3S[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)c(OC)cc2OC)cc1 |r| Show InChI InChI=1S/C23H30O7S/c1-4-30-15-7-5-13(6-8-15)9-14-10-16(18(29-3)11-17(14)28-2)23-22(27)21(26)20(25)19(12-24)31-23/h5-8,10-11,19-27H,4,9,12H2,1-3H3/t19-,20-,21+,22-,23+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of human SGLT2 expressed in CHOK1 cells assessed as inhibition of glucose uptake				J Med Chem 53: 3247-61 (2010) Article DOI: 10.1021/jm901893x BindingDB Entry DOI: 10.7270/Q2KH0NG6
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM50315420 ((1S)-1,5-Anhydro-1-[3-(4-ethoxybenzyl)-4-methoxyph...) Show SMILES CCOc1ccc(Cc2cc(ccc2OC)[C@@H]2S[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)cc1 |r| Show InChI InChI=1S/C22H28O6S/c1-3-28-16-7-4-13(5-8-16)10-15-11-14(6-9-17(15)27-2)22-21(26)20(25)19(24)18(12-23)29-22/h4-9,11,18-26H,3,10,12H2,1-2H3/t18-,19-,20+,21-,22+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of human SGLT2 expressed in CHOK1 cells assessed as inhibition of glucose uptake				J Med Chem 53: 3247-61 (2010) Article DOI: 10.1021/jm901893x BindingDB Entry DOI: 10.7270/Q2KH0NG6
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human))	BDBM364014 (3-Chloro-5-fluoro-N-{(exo)-8-[(2-methoxy-1,1-dimet...) Show SMILES COCC(C)(C)NC(=O)CN1[C@H]2CC[C@@H]1C[C@@H](CNC(=O)c1cc(F)cc(Cl)c1)C2 |r,THB:9:10:15.16.29:12.13| Show InChI InChI=1S/C22H31ClFN3O3/c1-22(2,13-30-3)26-20(28)12-27-18-4-5-19(27)7-14(6-18)11-25-21(29)15-8-16(23)10-17(24)9-15/h8-10,14,18-19H,4-7,11-13H2,1-3H3,(H,25,29)(H,26,28)/t14-,18-,19+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company					Assay Description The HEK293 cells having human Cav3.2 stably expressed therein were cultured at 37° C. in Alpha-MEM, to which 10% (v/v) fetal bovine serum (FBS), peni...				J Med Chem 49: 2440-55 (2006) BindingDB Entry DOI: 10.7270/Q2G73H2M
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human))	BDBM364008 (US9856250, 85) Show SMILES CC1=C(C2C=CC=CC2O1)C(=O)NC[C@H]1C[C@@H]2CC[C@H](C1)N2CC(=O)NC(C)(C)C |r,c:4,6,t:1,THB:22:21:20.14.15:17.18| Show InChI InChI=1S/C24H35N3O3/c1-15-22(19-7-5-6-8-20(19)30-15)23(29)25-13-16-11-17-9-10-18(12-16)27(17)14-21(28)26-24(2,3)4/h5-8,16-20H,9-14H2,1-4H3,(H,25,29)(H,26,28)/t16-,17-,18+,19?,20?	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company					Assay Description The HEK293 cells having human Cav3.2 stably expressed therein were cultured at 37° C. in Alpha-MEM, to which 10% (v/v) fetal bovine serum (FBS), peni...				J Med Chem 49: 2440-55 (2006) BindingDB Entry DOI: 10.7270/Q2G73H2M
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM50315435 ((1S)-1,5-Anhydro-1-[5-(4-ethoxybenzyl)-2-hydroxyph...) Show SMILES CCOc1ccc(Cc2ccc(O)c(c2)[C@@H]2S[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)cc1 |r| Show InChI InChI=1S/C21H26O6S/c1-2-27-14-6-3-12(4-7-14)9-13-5-8-16(23)15(10-13)21-20(26)19(25)18(24)17(11-22)28-21/h3-8,10,17-26H,2,9,11H2,1H3/t17-,18-,19+,20-,21+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of human SGLT2 expressed in CHOK1 cells assessed as inhibition of glucose uptake				J Med Chem 53: 3247-61 (2010) Article DOI: 10.1021/jm901893x BindingDB Entry DOI: 10.7270/Q2KH0NG6
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM50315428 ((1S)-1,5-Anhydro-1-[3-(4-tert-butylbenzyl)-4-chlor...) Show SMILES CC(C)(C)c1ccc(Cc2cc(ccc2Cl)[C@@H]2S[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)cc1 |r| Show InChI InChI=1S/C23H29ClO4S/c1-23(2,3)16-7-4-13(5-8-16)10-15-11-14(6-9-17(15)24)22-21(28)20(27)19(26)18(12-25)29-22/h4-9,11,18-22,25-28H,10,12H2,1-3H3/t18-,19-,20+,21-,22+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of human SGLT2 expressed in CHOK1 cells assessed as inhibition of glucose uptake				J Med Chem 53: 3247-61 (2010) Article DOI: 10.1021/jm901893x BindingDB Entry DOI: 10.7270/Q2KH0NG6
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human))	BDBM363992 (US9856250, 54) Show SMILES CC(C)(C)NC(=O)CN1[C@H]2CC[C@@H]1C[C@@H](CNC(=O)c1cc(O)cc(Cl)c1)C2 |r,THB:7:8:13.14.27:10.11| Show InChI InChI=1S/C21H30ClN3O3/c1-21(2,3)24-19(27)12-25-16-4-5-17(25)7-13(6-16)11-23-20(28)14-8-15(22)10-18(26)9-14/h8-10,13,16-17,26H,4-7,11-12H2,1-3H3,(H,23,28)(H,24,27)/t13-,16-,17+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company					Assay Description The HEK293 cells having human Cav3.2 stably expressed therein were cultured at 37° C. in Alpha-MEM, to which 10% (v/v) fetal bovine serum (FBS), peni...				J Med Chem 49: 2440-55 (2006) BindingDB Entry DOI: 10.7270/Q2G73H2M
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human))	BDBM364003 (US9856250, 77) Show SMILES Cc1ccc(cc1)C(=O)NC[C@H]1C[C@@H]2CC[C@H](C1)N2CC(=O)NC(C)(C)C |r,THB:19:18:17.11.12:14.15| Show InChI InChI=1S/C22H33N3O2/c1-15-5-7-17(8-6-15)21(27)23-13-16-11-18-9-10-19(12-16)25(18)14-20(26)24-22(2,3)4/h5-8,16,18-19H,9-14H2,1-4H3,(H,23,27)(H,24,26)/t16-,18-,19+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company					Assay Description The HEK293 cells having human Cav3.2 stably expressed therein were cultured at 37° C. in Alpha-MEM, to which 10% (v/v) fetal bovine serum (FBS), peni...				J Med Chem 49: 2440-55 (2006) BindingDB Entry DOI: 10.7270/Q2G73H2M
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM20875 (1-(2,4-dihydroxy-6-{[(2S,3R,4S,5S,6R)-3,4,5-trihyd...) Show SMILES OC[C@H]1O[C@@H](Oc2cc(O)cc(O)c2C(=O)CCc2ccc(O)cc2)[C@H](O)[C@@H](O)[C@@H]1O Show InChI InChI=1S/C21H24O10/c22-9-16-18(27)19(28)20(29)21(31-16)30-15-8-12(24)7-14(26)17(15)13(25)6-3-10-1-4-11(23)5-2-10/h1-2,4-5,7-8,16,18-24,26-29H,3,6,9H2/t16-,18-,19+,20-,21-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of human SGLT2 expressed in CHOK1 cells assessed as inhibition of glucose uptake				J Med Chem 53: 3247-61 (2010) Article DOI: 10.1021/jm901893x BindingDB Entry DOI: 10.7270/Q2KH0NG6
					More data for this Ligand-Target Pair				3D Structure (crystal)
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human))	BDBM363994 (US9856250, 56) Show SMILES CCc1cc(F)cc(c1)C(=O)NC[C@H]1C[C@@H]2CC[C@H](C1)N2CC(=O)NC(C)(C)C |r,THB:21:20:19.13.14:16.17| Show InChI InChI=1S/C23H34FN3O2/c1-5-15-8-17(12-18(24)9-15)22(29)25-13-16-10-19-6-7-20(11-16)27(19)14-21(28)26-23(2,3)4/h8-9,12,16,19-20H,5-7,10-11,13-14H2,1-4H3,(H,25,29)(H,26,28)/t16-,19-,20+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company					Assay Description The HEK293 cells having human Cav3.2 stably expressed therein were cultured at 37° C. in Alpha-MEM, to which 10% (v/v) fetal bovine serum (FBS), peni...				J Med Chem 49: 2440-55 (2006) BindingDB Entry DOI: 10.7270/Q2G73H2M
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human))	BDBM363993 (US9856250, 55) Show SMILES Cc1cc(F)cc(c1)C(=O)NC[C@H]1C[C@@H]2CC[C@H](C1)N2CC(=O)NC(C)(C)C |r,THB:20:19:18.12.13:15.16| Show InChI InChI=1S/C22H32FN3O2/c1-14-7-16(11-17(23)8-14)21(28)24-12-15-9-18-5-6-19(10-15)26(18)13-20(27)25-22(2,3)4/h7-8,11,15,18-19H,5-6,9-10,12-13H2,1-4H3,(H,24,28)(H,25,27)/t15-,18-,19+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company					Assay Description The HEK293 cells having human Cav3.2 stably expressed therein were cultured at 37° C. in Alpha-MEM, to which 10% (v/v) fetal bovine serum (FBS), peni...				J Med Chem 49: 2440-55 (2006) BindingDB Entry DOI: 10.7270/Q2G73H2M
					More data for this Ligand-Target Pair
Sodium/glucose cotransporter 2 (Homo sapiens (Human))	BDBM50315434 ((1S)-1,5-Anhydro-1-[5-(4-ethoxybenzyl)-2-methoxyph...) Show SMILES CCOc1ccc(Cc2ccc(OC)c(c2)[C@@H]2S[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)cc1 |r| Show InChI InChI=1S/C22H28O6S/c1-3-28-15-7-4-13(5-8-15)10-14-6-9-17(27-2)16(11-14)22-21(26)20(25)19(24)18(12-23)29-22/h4-9,11,18-26H,3,10,12H2,1-2H3/t18-,19-,20+,21-,22+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	38	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of human SGLT2 expressed in CHOK1 cells assessed as inhibition of glucose uptake				J Med Chem 53: 3247-61 (2010) Article DOI: 10.1021/jm901893x BindingDB Entry DOI: 10.7270/Q2KH0NG6
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human))	BDBM364020 (US9856250, 113) Show SMILES CC(C)(C)NC(=O)CN1[C@H]2CC[C@@H]1C[C@@H](CNC(=O)c1cc(F)cc(Cl)c1)C2 |r,THB:7:8:13.14.27:10.11| Show InChI InChI=1S/C21H29ClFN3O2/c1-21(2,3)25-19(27)12-26-17-4-5-18(26)7-13(6-17)11-24-20(28)14-8-15(22)10-16(23)9-14/h8-10,13,17-18H,4-7,11-12H2,1-3H3,(H,24,28)(H,25,27)/t13-,17-,18+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	39	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company					Assay Description The HEK293 cells having human Cav3.2 stably expressed therein were cultured at 37° C. in Alpha-MEM, to which 10% (v/v) fetal bovine serum (FBS), peni...				J Med Chem 49: 2440-55 (2006) BindingDB Entry DOI: 10.7270/Q2G73H2M
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human))	BDBM363998 (US9856250, 67) Show SMILES CC(C)(C)NC(=O)CN1[C@H]2CC[C@@H]1C[C@@H](CNC(=O)C1C(C)(C)C1(C)C)C2 |r,THB:7:8:13.14.26:10.11| Show InChI InChI=1S/C22H39N3O2/c1-20(2,3)24-17(26)13-25-15-8-9-16(25)11-14(10-15)12-23-19(27)18-21(4,5)22(18,6)7/h14-16,18H,8-13H2,1-7H3,(H,23,27)(H,24,26)/t14-,15-,16+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	42	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company					Assay Description The HEK293 cells having human Cav3.2 stably expressed therein were cultured at 37° C. in Alpha-MEM, to which 10% (v/v) fetal bovine serum (FBS), peni...				J Med Chem 49: 2440-55 (2006) BindingDB Entry DOI: 10.7270/Q2G73H2M
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human))	BDBM364004 (US9856250, 78) Show SMILES CC(C)(C)NC(=O)CN1[C@H]2CC[C@@H]1C[C@@H](CNC(=O)c1ccc(F)cc1)C2 |r,THB:7:8:13.14.26:10.11| Show InChI InChI=1S/C21H30FN3O2/c1-21(2,3)24-19(26)13-25-17-8-9-18(25)11-14(10-17)12-23-20(27)15-4-6-16(22)7-5-15/h4-7,14,17-18H,8-13H2,1-3H3,(H,23,27)(H,24,26)/t14-,17-,18+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	44	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company					Assay Description The HEK293 cells having human Cav3.2 stably expressed therein were cultured at 37° C. in Alpha-MEM, to which 10% (v/v) fetal bovine serum (FBS), peni...				J Med Chem 49: 2440-55 (2006) BindingDB Entry DOI: 10.7270/Q2G73H2M
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human))	BDBM364104 (N-[(endo)-8-(tert-Butylcarbamoyl)methyl-8-azabicyc...) Show SMILES CC(C)(C)NC(=O)CN1[C@H]2CC[C@@H]1C[C@H](CNC(=O)C13CC4CC(CC(C4)C1)C3)C2 |r,TLB:26:25:28:22.20.21,THB:7:8:13.14.29:11.10,24:25:28.23.22:20| Show InChI InChI=1S/C25H41N3O2/c1-24(2,3)27-22(29)15-28-20-4-5-21(28)10-19(9-20)14-26-23(30)25-11-16-6-17(12-25)8-18(7-16)13-25/h16-21H,4-15H2,1-3H3,(H,26,30)(H,27,29)/t16?,17?,18?,19-,20+,21-,25?	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	44	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company					Assay Description The HEK293 cells having human Cav3.2 stably expressed therein were cultured at 37° C. in Alpha-MEM, to which 10% (v/v) fetal bovine serum (FBS), peni...				J Med Chem 49: 2440-55 (2006) BindingDB Entry DOI: 10.7270/Q2G73H2M
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human))	BDBM364005 (US9856250, 79) Show SMILES CC(C)(C)NC(=O)CN1[C@H]2CC[C@@H]1C[C@@H](CNC(=O)c1cc(F)cc(c1)C#C)C2 |r,THB:7:8:13.14.28:10.11| Show InChI InChI=1S/C23H30FN3O2/c1-5-15-8-17(12-18(24)9-15)22(29)25-13-16-10-19-6-7-20(11-16)27(19)14-21(28)26-23(2,3)4/h1,8-9,12,16,19-20H,6-7,10-11,13-14H2,2-4H3,(H,25,29)(H,26,28)/t16-,19-,20+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	45	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company					Assay Description The HEK293 cells having human Cav3.2 stably expressed therein were cultured at 37° C. in Alpha-MEM, to which 10% (v/v) fetal bovine serum (FBS), peni...				J Med Chem 49: 2440-55 (2006) BindingDB Entry DOI: 10.7270/Q2G73H2M
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human))	BDBM363977 (US9856250, 16) Show SMILES CC(C)(C)NC(=O)CN1[C@H]2CC[C@@H]1C[C@@H](CNC(=O)c1csc3CCCCc13)C2 |r,THB:7:8:13.14.28:10.11| Show InChI InChI=1S/C23H35N3O2S/c1-23(2,3)25-21(27)13-26-16-8-9-17(26)11-15(10-16)12-24-22(28)19-14-29-20-7-5-4-6-18(19)20/h14-17H,4-13H2,1-3H3,(H,24,28)(H,25,27)/t15-,16-,17+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	47	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company					Assay Description The HEK293 cells having human Cav3.2 stably expressed therein were cultured at 37° C. in Alpha-MEM, to which 10% (v/v) fetal bovine serum (FBS), peni...				J Med Chem 49: 2440-55 (2006) BindingDB Entry DOI: 10.7270/Q2G73H2M
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human))	BDBM363990 (US9856250, 52) Show SMILES CC(C)(C)NC(=O)CN1[C@H]2CC[C@@H]1C[C@@H](CNC(=O)c1cccc(Cl)c1)C2 |r,THB:7:8:13.14.26:10.11| Show InChI InChI=1S/C21H30ClN3O2/c1-21(2,3)24-19(26)13-25-17-7-8-18(25)10-14(9-17)12-23-20(27)15-5-4-6-16(22)11-15/h4-6,11,14,17-18H,7-10,12-13H2,1-3H3,(H,23,27)(H,24,26)/t14-,17-,18+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	48	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company					Assay Description The HEK293 cells having human Cav3.2 stably expressed therein were cultured at 37° C. in Alpha-MEM, to which 10% (v/v) fetal bovine serum (FBS), peni...				J Med Chem 49: 2440-55 (2006) BindingDB Entry DOI: 10.7270/Q2G73H2M
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human))	BDBM363979 (US9856250, 19) Show SMILES Cc1oc2CCCCc2c1NC(=O)C[C@H]1C[C@@H]2CC[C@H](C1)N2CC(=O)NC(C)(C)C |r,THB:22:21:20.14.15:17.18| Show InChI InChI=1S/C24H37N3O3/c1-15-23(19-7-5-6-8-20(19)30-15)25-21(28)13-16-11-17-9-10-18(12-16)27(17)14-22(29)26-24(2,3)4/h16-18H,5-14H2,1-4H3,(H,25,28)(H,26,29)/t16-,17-,18+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	48	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company					Assay Description The HEK293 cells having human Cav3.2 stably expressed therein were cultured at 37° C. in Alpha-MEM, to which 10% (v/v) fetal bovine serum (FBS), peni...				J Med Chem 49: 2440-55 (2006) BindingDB Entry DOI: 10.7270/Q2G73H2M
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human))	BDBM363991 (US9856250, 53) Show SMILES COc1cc(Cl)cc(c1)C(=O)NC[C@H]1C[C@@H]2CC[C@H](C1)N2CC(=O)NC(C)(C)C |r,THB:21:20:19.13.14:16.17| Show InChI InChI=1S/C22H32ClN3O3/c1-22(2,3)25-20(27)13-26-17-5-6-18(26)8-14(7-17)12-24-21(28)15-9-16(23)11-19(10-15)29-4/h9-11,14,17-18H,5-8,12-13H2,1-4H3,(H,24,28)(H,25,27)/t14-,17-,18+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	49	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company					Assay Description The HEK293 cells having human Cav3.2 stably expressed therein were cultured at 37° C. in Alpha-MEM, to which 10% (v/v) fetal bovine serum (FBS), peni...				J Med Chem 49: 2440-55 (2006) BindingDB Entry DOI: 10.7270/Q2G73H2M
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human))	BDBM363987 (US9856250, 36) Show SMILES CCN1C=C(C2C=CC=CC12)C(=O)NC[C@H]1C[C@@H]2CC[C@H](C1)N2CC(=O)NC(C)(C)C |r,c:3,6,8,THB:23:22:21.15.16:18.19| Show InChI InChI=1S/C25H38N4O2/c1-5-28-15-21(20-8-6-7-9-22(20)28)24(31)26-14-17-12-18-10-11-19(13-17)29(18)16-23(30)27-25(2,3)4/h6-9,15,17-20,22H,5,10-14,16H2,1-4H3,(H,26,31)(H,27,30)/t17-,18-,19+,20?,22?	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	49	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company					Assay Description The HEK293 cells having human Cav3.2 stably expressed therein were cultured at 37° C. in Alpha-MEM, to which 10% (v/v) fetal bovine serum (FBS), peni...				J Med Chem 49: 2440-55 (2006) BindingDB Entry DOI: 10.7270/Q2G73H2M
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human))	BDBM364015 (US9856250, 107) Show SMILES CC(C)(C)NC(=O)CN1[C@H]2CC[C@@H]1C[C@@H](CNC(=C)C13CC4CC(CC(C4)C1)C3)C2 |r,TLB:26:25:28:22.21.20,THB:7:8:13.14.29:10.11,24:25:28.23.22:20| Show InChI InChI=1S/C26H43N3O/c1-17(26-12-18-7-19(13-26)9-20(8-18)14-26)27-15-21-10-22-5-6-23(11-21)29(22)16-24(30)28-25(2,3)4/h18-23,27H,1,5-16H2,2-4H3,(H,28,30)/t18?,19?,20?,21-,22-,23+,26?	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	49	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company					Assay Description The HEK293 cells having human Cav3.2 stably expressed therein were cultured at 37° C. in Alpha-MEM, to which 10% (v/v) fetal bovine serum (FBS), peni...				J Med Chem 49: 2440-55 (2006) BindingDB Entry DOI: 10.7270/Q2G73H2M
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human))	BDBM364108 (US9856250, 160) Show SMILES Cn1nc(cc1C(=O)NC[C@@H]1C[C@@H]2CC[C@H](C1)N2CC(=O)NC(C)(C)C)C1CC1 |r,THB:18:17:16.10.11:14.13| Show InChI InChI=1S/C22H35N5O2/c1-22(2,3)24-20(28)13-27-16-7-8-17(27)10-14(9-16)12-23-21(29)19-11-18(15-5-6-15)25-26(19)4/h11,14-17H,5-10,12-13H2,1-4H3,(H,23,29)(H,24,28)/t14-,16+,17-	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	49	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company					Assay Description The HEK293 cells having human Cav3.2 stably expressed therein were cultured at 37° C. in Alpha-MEM, to which 10% (v/v) fetal bovine serum (FBS), peni...				J Med Chem 49: 2440-55 (2006) BindingDB Entry DOI: 10.7270/Q2G73H2M
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human))	BDBM364103 (US9856250, 131) Show SMILES CC(C)(C)NC(=O)CN1[C@H]2CC[C@@H]1C[C@H](CC(=O)NC13CC4CC1CC(C3)C4)C2 |r,TLB:22:21:23.24:26,THB:7:8:13.14.28:11.10,24:25:20:22.23| Show InChI InChI=1S/C24H39N3O2/c1-23(2,3)25-22(29)14-27-19-4-5-20(27)10-15(9-19)11-21(28)26-24-12-16-6-17(13-24)8-18(24)7-16/h15-20H,4-14H2,1-3H3,(H,25,29)(H,26,28)/t15-,16?,17?,18?,19+,20-,24?	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	49	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company					Assay Description The HEK293 cells having human Cav3.2 stably expressed therein were cultured at 37° C. in Alpha-MEM, to which 10% (v/v) fetal bovine serum (FBS), peni...				J Med Chem 49: 2440-55 (2006) BindingDB Entry DOI: 10.7270/Q2G73H2M
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human))	BDBM363999 (US9856250, 69) Show SMILES Cn1nc(cc1C(=O)NC[C@H]1C[C@@H]2CC[C@H](C1)N2CC(=O)NC(C)(C)C)C(C)(C)C |r,THB:18:17:16.10.11:13.14| Show InChI InChI=1S/C23H39N5O2/c1-22(2,3)19-12-18(27(7)26-19)21(30)24-13-15-10-16-8-9-17(11-15)28(16)14-20(29)25-23(4,5)6/h12,15-17H,8-11,13-14H2,1-7H3,(H,24,30)(H,25,29)/t15-,16-,17+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	51	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company					Assay Description The HEK293 cells having human Cav3.2 stably expressed therein were cultured at 37° C. in Alpha-MEM, to which 10% (v/v) fetal bovine serum (FBS), peni...				J Med Chem 49: 2440-55 (2006) BindingDB Entry DOI: 10.7270/Q2G73H2M
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human))	BDBM364001 (US9856250, 72) Show SMILES COc1cc(C)cc(c1)C(=O)NC[C@H]1C[C@@H]2CC[C@H](C1)N2CC(=O)NC(C)(C)C |r,THB:21:20:19.13.14:16.17| Show InChI InChI=1S/C23H35N3O3/c1-15-8-17(12-20(9-15)29-5)22(28)24-13-16-10-18-6-7-19(11-16)26(18)14-21(27)25-23(2,3)4/h8-9,12,16,18-19H,6-7,10-11,13-14H2,1-5H3,(H,24,28)(H,25,27)/t16-,18-,19+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company					Assay Description The HEK293 cells having human Cav3.2 stably expressed therein were cultured at 37° C. in Alpha-MEM, to which 10% (v/v) fetal bovine serum (FBS), peni...				J Med Chem 49: 2440-55 (2006) BindingDB Entry DOI: 10.7270/Q2G73H2M
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human))	BDBM364011 (US9856250, 96) Show SMILES COc1cc(C)cc(c1)C(=O)NC[C@H]1C[C@@H]2CC[C@H](C1)N2CC(=O)NC1(CC1)C(F)(F)F |r,THB:21:20:19.13.14:16.17| Show InChI InChI=1S/C23H30F3N3O3/c1-14-7-16(11-19(8-14)32-2)21(31)27-12-15-9-17-3-4-18(10-15)29(17)13-20(30)28-22(5-6-22)23(24,25)26/h7-8,11,15,17-18H,3-6,9-10,12-13H2,1-2H3,(H,27,31)(H,28,30)/t15-,17-,18+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	58	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company					Assay Description The HEK293 cells having human Cav3.2 stably expressed therein were cultured at 37° C. in Alpha-MEM, to which 10% (v/v) fetal bovine serum (FBS), peni...				J Med Chem 49: 2440-55 (2006) BindingDB Entry DOI: 10.7270/Q2G73H2M
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human))	BDBM364042 (N-tert-Butyl-2- [(exo)-3-(4-methyl-1H-benzimidazol...) Show SMILES Cc1cccc2[nH]c(C[C@H]3C[C@@H]4CC[C@H](C3)N4CC(=O)NC(C)(C)C)nc12 |r,THB:17:16:15.9.10:13.12| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	59	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company					Assay Description The HEK293 cells having human Cav3.2 stably expressed therein were cultured at 37° C. in Alpha-MEM, to which 10% (v/v) fetal bovine serum (FBS), peni...				J Med Chem 49: 2440-55 (2006) BindingDB Entry DOI: 10.7270/Q2G73H2M
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human))	BDBM363995 (US9856250, 59) Show SMILES CC(C)(C)NC(=O)CN1[C@H]2CC[C@@H]1C[C@@H](CNC(=O)c1ccc3OCCCc3c1)C2 |r,THB:7:8:13.14.29:10.11| Show InChI InChI=1S/C24H35N3O3/c1-24(2,3)26-22(28)15-27-19-7-8-20(27)12-16(11-19)14-25-23(29)18-6-9-21-17(13-18)5-4-10-30-21/h6,9,13,16,19-20H,4-5,7-8,10-12,14-15H2,1-3H3,(H,25,29)(H,26,28)/t16-,19-,20+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	61	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company					Assay Description The HEK293 cells having human Cav3.2 stably expressed therein were cultured at 37° C. in Alpha-MEM, to which 10% (v/v) fetal bovine serum (FBS), peni...				J Med Chem 49: 2440-55 (2006) BindingDB Entry DOI: 10.7270/Q2G73H2M
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human))	BDBM364027 (US9856250, 115) Show SMILES CC1(CC1)NC(=O)CN1[C@H]2CC[C@@H]1C[C@@H](CNC(=O)c1cc(F)cc(Cl)c1)C2 |r,THB:7:8:13.14.27:10.11| Show InChI InChI=1S/C21H27ClFN3O2/c1-21(4-5-21)25-19(27)12-26-17-2-3-18(26)7-13(6-17)11-24-20(28)14-8-15(22)10-16(23)9-14/h8-10,13,17-18H,2-7,11-12H2,1H3,(H,24,28)(H,25,27)/t13-,17-,18+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	63	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company					Assay Description The HEK293 cells having human Cav3.2 stably expressed therein were cultured at 37° C. in Alpha-MEM, to which 10% (v/v) fetal bovine serum (FBS), peni...				J Med Chem 49: 2440-55 (2006) BindingDB Entry DOI: 10.7270/Q2G73H2M
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human))	BDBM364000 (US9856250, 71) Show SMILES CC(C)(C)CCC(=O)NC[C@H]1C[C@@H]2CC[C@H](C1)N2CC(=O)NC(C)(C)C |r,THB:18:17:16.10.11:13.14| Show InChI InChI=1S/C21H39N3O2/c1-20(2,3)10-9-18(25)22-13-15-11-16-7-8-17(12-15)24(16)14-19(26)23-21(4,5)6/h15-17H,7-14H2,1-6H3,(H,22,25)(H,23,26)/t15-,16-,17+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	64	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company					Assay Description The HEK293 cells having human Cav3.2 stably expressed therein were cultured at 37° C. in Alpha-MEM, to which 10% (v/v) fetal bovine serum (FBS), peni...				J Med Chem 49: 2440-55 (2006) BindingDB Entry DOI: 10.7270/Q2G73H2M
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human))	BDBM363983 (US9856250, 28) Show SMILES CC(C)(C)NC(=O)CN1[C@H]2CC[C@@H]1C[C@@H](CNC(=O)C(C)(C)Oc1ccccc1)C2 |r,THB:7:8:13.14.29:10.11| Show InChI InChI=1S/C24H37N3O3/c1-23(2,3)26-21(28)16-27-18-11-12-19(27)14-17(13-18)15-25-22(29)24(4,5)30-20-9-7-6-8-10-20/h6-10,17-19H,11-16H2,1-5H3,(H,25,29)(H,26,28)/t17-,18-,19+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	65	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company					Assay Description The HEK293 cells having human Cav3.2 stably expressed therein were cultured at 37° C. in Alpha-MEM, to which 10% (v/v) fetal bovine serum (FBS), peni...				J Med Chem 49: 2440-55 (2006) BindingDB Entry DOI: 10.7270/Q2G73H2M
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human))	BDBM364102 (N-(Adamantan-1-yl)-2-[(endo)-8-(tert-butylcarbamoy...) Show SMILES CC(C)(C)NC(=O)CN1[C@H]2CC[C@@H]1C[C@H](CC(=O)NC13CC4CC(CC(C4)C1)C3)C2 |r,TLB:26:25:28:22.20.21,THB:7:8:13.14.29:11.10,24:25:28.23.22:20| Show InChI InChI=1S/C25H41N3O2/c1-24(2,3)26-23(30)15-28-20-4-5-21(28)10-16(9-20)11-22(29)27-25-12-17-6-18(13-25)8-19(7-17)14-25/h16-21H,4-15H2,1-3H3,(H,26,30)(H,27,29)/t16-,17?,18?,19?,20+,21-,25?	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	66	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company					Assay Description The HEK293 cells having human Cav3.2 stably expressed therein were cultured at 37° C. in Alpha-MEM, to which 10% (v/v) fetal bovine serum (FBS), peni...				J Med Chem 49: 2440-55 (2006) BindingDB Entry DOI: 10.7270/Q2G73H2M
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human))	BDBM363988 (US9856250, 37) Show SMILES CN1C2C=CC=CC2C(C(=O)NC[C@H]2C[C@@H]3CC[C@H](C2)N3CC(=O)NC(C)(C)C)=C1C |r,c:3,5,31,THB:21:20:19.13.14:16.17| Show InChI InChI=1S/C25H38N4O2/c1-16-23(20-8-6-7-9-21(20)28(16)5)24(31)26-14-17-12-18-10-11-19(13-17)29(18)15-22(30)27-25(2,3)4/h6-9,17-21H,10-15H2,1-5H3,(H,26,31)(H,27,30)/t17-,18-,19+,20?,21?	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	67	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company					Assay Description The HEK293 cells having human Cav3.2 stably expressed therein were cultured at 37° C. in Alpha-MEM, to which 10% (v/v) fetal bovine serum (FBS), peni...				J Med Chem 49: 2440-55 (2006) BindingDB Entry DOI: 10.7270/Q2G73H2M
					More data for this Ligand-Target Pair
Voltage-dependent T-type calcium channel subunit alpha-1H (Homo sapiens (Human))	BDBM363897 (2-[(exo)-8-(tert-Butylcarbamoyl)methyl-8-azabicycl...) Show SMILES CC(C)(C)NC(=O)CN1[C@H]2CC[C@@H]1C[C@@H](CC(=O)Nc1cccc(Cl)c1)C2 |r,THB:7:8:13.14.26:10.11| Show InChI InChI=1S/C21H30ClN3O2/c1-21(2,3)24-20(27)13-25-17-7-8-18(25)10-14(9-17)11-19(26)23-16-6-4-5-15(22)12-16/h4-6,12,14,17-18H,7-11,13H2,1-3H3,(H,23,26)(H,24,27)/t14-,17-,18+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	68	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company					Assay Description The HEK293 cells having human Cav3.2 stably expressed therein were cultured at 37° C. in Alpha-MEM, to which 10% (v/v) fetal bovine serum (FBS), peni...				J Med Chem 49: 2440-55 (2006) BindingDB Entry DOI: 10.7270/Q2G73H2M
					More data for this Ligand-Target Pair

Displayed 1 to 50 (of 98 total )  |  Next  |  Last  >>

Jump to: