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Compile Data Set for Download or QSAR

Found 415 hits with Last Name = 'chu' and Initial = 'jc'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Estrogen receptor


(Homo sapiens (Human))		BDBM50532101
PNG
(CHEMBL4439408)
Show SMILES Oc1ccc2C3=C(CCOc2c1)c1cc(O)ccc1OC3c1ccc(OCCN2CC(CF)C2)cc1 |c:5|
Show InChI InChI=1S/C29H28FNO5/c30-15-18-16-31(17-18)10-12-34-22-5-1-19(2-6-22)29-28-23(25-13-20(32)4-8-26(25)36-29)9-11-35-27-14-21(33)3-7-24(27)28/h1-8,13-14,18,29,32-33H,9-12,15-17H2
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n/an/a 0.0240n/an/an/an/an/an/a



Genentech Inc.

Curated by ChEMBL


Assay Description
Induction of ERalpha degradation in human MCF7 cells after 4 hrs by Alexafluor-488 conjugate anti-mouse IgG antibody/Hoechst 33342 staining based imm...

Bioorg Med Chem Lett 29: 905-911 (2019)


Article DOI: 10.1016/j.bmcl.2019.01.036
BindingDB Entry DOI: 10.7270/Q2Q52T3W
More data for this
Ligand-Target Pair
Estrogen receptor


(Homo sapiens (Human))		BDBM50532101
PNG
(CHEMBL4439408)
Show SMILES Oc1ccc2C3=C(CCOc2c1)c1cc(O)ccc1OC3c1ccc(OCCN2CC(CF)C2)cc1 |c:5|
Show InChI InChI=1S/C29H28FNO5/c30-15-18-16-31(17-18)10-12-34-22-5-1-19(2-6-22)29-28-23(25-13-20(32)4-8-26(25)36-29)9-11-35-27-14-21(33)3-7-24(27)28/h1-8,13-14,18,29,32-33H,9-12,15-17H2
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n/an/a 0.0240n/an/an/an/an/an/a



Genentech Inc.

Curated by ChEMBL


Assay Description
Induction of ERalpha degradation in human MCF7 cells after 4 hrs by Alexafluor-488 conjugate anti-mouse IgG antibody/Hoechst 33342 staining based imm...

Bioorg Med Chem Lett 29: 905-911 (2019)


Article DOI: 10.1016/j.bmcl.2019.01.036
BindingDB Entry DOI: 10.7270/Q2Q52T3W
More data for this
Ligand-Target Pair
Glucocorticoid receptor


(Homo sapiens (Human))		BDBM50206900
PNG
(CHEMBL3895181)
Show SMILES [H][C@@]12CC[C@@](O)(C#CC)[C@@]1(C)C[C@H](OCC=C)[C@]1([H])c3ccc(cc3CC[C@@]21[H])C(=O)Nc1cccnc1C |r|
Show InChI InChI=1S/C31H36N2O3/c1-5-14-31(35)15-13-25-24-12-9-21-18-22(29(34)33-26-8-7-16-32-20(26)3)10-11-23(21)28(24)27(36-17-6-2)19-30(25,31)4/h6-8,10-11,16,18,24-25,27-28,35H,2,9,12-13,15,17,19H2,1,3-4H3,(H,33,34)/t24-,25-,27-,28+,30-,31-/m0/s1
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n/an/a 0.0300n/an/an/an/an/an/a



The Scripps Research Institute

Curated by ChEMBL


Assay Description
Antagonist activity at GR in human HepG2 cells assessed as inhibition of protein mediated-transcriptional activity by MMTV-promoter driven luciferase...

Bioorg Med Chem Lett 27: 347-353 (2017)


Article DOI: 10.1016/j.bmcl.2016.11.007
BindingDB Entry DOI: 10.7270/Q24B339Q
More data for this
Ligand-Target Pair
Estrogen receptor


(Homo sapiens (Human))		BDBM368199
PNG
((S)-2-(4-(2-(3-(fluoromethyl)azetidin-1-yl)ethoxy)...)
Show SMILES CC1=C([C@@H](Oc2ccc(O)cc12)c1ccc(OCCN2CC(CF)C2)cc1)c1cccc(O)c1 |r,t:1|
Show InChI InChI=1S/C28H28FNO4/c1-18-25-14-23(32)7-10-26(25)34-28(27(18)21-3-2-4-22(31)13-21)20-5-8-24(9-6-20)33-12-11-30-16-19(15-29)17-30/h2-10,13-14,19,28,31-32H,11-12,15-17H2,1H3/t28-/m0/s1
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n/an/a 0.0300n/an/an/an/an/an/a



Genentech Inc.

Curated by ChEMBL


Assay Description
Induction of ERalpha degradation in human MCF7 cells after 4 hrs by Alexafluor-488 conjugate anti-mouse IgG antibody/Hoechst 33342 staining based imm...

Bioorg Med Chem Lett 29: 905-911 (2019)


Article DOI: 10.1016/j.bmcl.2019.01.036
BindingDB Entry DOI: 10.7270/Q2Q52T3W
More data for this
Ligand-Target Pair		3D
3D Structure (crystal)
Estrogen receptor


(Homo sapiens (Human))		BDBM50532103
PNG
(CHEMBL4464224)
Show SMILES Oc1ccc2C3=C(C(Oc2c1)c1ccc(OCCN2CC(CF)C2)cc1)c1ccc(O)cc1OCC3 |c:5|
Show InChI InChI=1S/C29H28FNO5/c30-15-18-16-31(17-18)10-12-34-22-5-1-19(2-6-22)29-28-24(23-7-3-21(33)14-27(23)36-29)9-11-35-26-13-20(32)4-8-25(26)28/h1-8,13-14,18,29,32-33H,9-12,15-17H2
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n/an/a 0.0450n/an/an/an/an/an/a



Genentech Inc.

Curated by ChEMBL


Assay Description
Induction of ERalpha degradation in human MCF7 cells after 4 hrs by Alexafluor-488 conjugate anti-mouse IgG antibody/Hoechst 33342 staining based imm...

Bioorg Med Chem Lett 29: 905-911 (2019)


Article DOI: 10.1016/j.bmcl.2019.01.036
BindingDB Entry DOI: 10.7270/Q2Q52T3W
More data for this
Ligand-Target Pair		3D
3D Structure (crystal)
Estrogen receptor


(Homo sapiens (Human))		BDBM50532105
PNG
(CHEMBL4449709)
Show SMILES C[C@@H](COc1ccc(cc1)C1Oc2cc(O)ccc2C2=C1c1ccc(O)cc1OCC2)N1CC[C@@H](CF)C1 |r,c:21|
Show InChI InChI=1S/C31H32FNO5/c1-19(33-12-10-20(16-32)17-33)18-37-24-6-2-21(3-7-24)31-30-26(25-8-4-23(35)15-29(25)38-31)11-13-36-28-14-22(34)5-9-27(28)30/h2-9,14-15,19-20,31,34-35H,10-13,16-18H2,1H3/t19-,20-,31?/m0/s1
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n/an/a 0.0510n/an/an/an/an/an/a



Genentech Inc.

Curated by ChEMBL


Assay Description
Induction of ERalpha degradation in human MCF7 cells after 4 hrs by Alexafluor-488 conjugate anti-mouse IgG antibody/Hoechst 33342 staining based imm...

Bioorg Med Chem Lett 29: 905-911 (2019)


Article DOI: 10.1016/j.bmcl.2019.01.036
BindingDB Entry DOI: 10.7270/Q2Q52T3W
More data for this
Ligand-Target Pair
Estrogen receptor


(Homo sapiens (Human))		BDBM50532102
PNG
(CHEMBL4437985)
Show SMILES Oc1ccc2C3=C([C@@H](Oc2c1)c1ccc(OCCN2CC(CF)C2)cc1)c1ccc(O)cc1OCC3 |r,c:5|
Show InChI InChI=1S/C29H28FNO5/c30-15-18-16-31(17-18)10-12-34-22-5-1-19(2-6-22)29-28-24(23-7-3-21(33)14-27(23)36-29)9-11-35-26-13-20(32)4-8-25(26)28/h1-8,13-14,18,29,32-33H,9-12,15-17H2/t29-/m0/s1
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n/an/a 0.0550n/an/an/an/an/an/a



Genentech Inc.

Curated by ChEMBL


Assay Description
Induction of ERalpha degradation in human MCF7 cells after 4 hrs by Alexafluor-488 conjugate anti-mouse IgG antibody/Hoechst 33342 staining based imm...

Bioorg Med Chem Lett 29: 905-911 (2019)


Article DOI: 10.1016/j.bmcl.2019.01.036
BindingDB Entry DOI: 10.7270/Q2Q52T3W
More data for this
Ligand-Target Pair		3D
3D Structure (crystal)
Estrogen receptor


(Homo sapiens (Human))		BDBM50532098
PNG
(CHEMBL4464058)
Show SMILES Oc1ccc2C3=C([C@H](Oc2c1)c1ccc(OCCN2CC(CF)C2)cc1)c1ccc(O)cc1OCC3 |r,c:5|
Show InChI InChI=1S/C29H28FNO5/c30-15-18-16-31(17-18)10-12-34-22-5-1-19(2-6-22)29-28-24(23-7-3-21(33)14-27(23)36-29)9-11-35-26-13-20(32)4-8-25(26)28/h1-8,13-14,18,29,32-33H,9-12,15-17H2/t29-/m1/s1
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n/an/a 0.0590n/an/an/an/an/an/a



Genentech Inc.

Curated by ChEMBL


Assay Description
Induction of ERalpha degradation in human MCF7 cells after 4 hrs by Alexafluor-488 conjugate anti-mouse IgG antibody/Hoechst 33342 staining based imm...

Bioorg Med Chem Lett 29: 905-911 (2019)


Article DOI: 10.1016/j.bmcl.2019.01.036
BindingDB Entry DOI: 10.7270/Q2Q52T3W
More data for this
Ligand-Target Pair		3D
3D Structure (crystal)
Glucocorticoid receptor


(Homo sapiens (Human))		BDBM50206950
PNG
(CHEMBL3933702)
Show SMILES [H][C@@]12CC[C@@](O)(C#CC)[C@@]1(C)C[C@H](OCc1ccc(Cl)cc1)[C@]1([H])c3ccc(cc3CC[C@@]21[H])C(=O)Nc1cccnc1C |r|
Show InChI InChI=1S/C35H37ClN2O3/c1-4-16-35(40)17-15-29-28-14-9-24-19-25(33(39)38-30-6-5-18-37-22(30)2)10-13-27(24)32(28)31(20-34(29,35)3)41-21-23-7-11-26(36)12-8-23/h5-8,10-13,18-19,28-29,31-32,40H,9,14-15,17,20-21H2,1-3H3,(H,38,39)/t28-,29-,31-,32+,34-,35-/m0/s1
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n/an/a 0.0700n/an/an/an/an/an/a



The Scripps Research Institute

Curated by ChEMBL


Assay Description
Antagonist activity at GR in human HepG2 cells assessed as inhibition of protein mediated-transcriptional activity by MMTV-promoter driven luciferase...

Bioorg Med Chem Lett 27: 347-353 (2017)


Article DOI: 10.1016/j.bmcl.2016.11.007
BindingDB Entry DOI: 10.7270/Q24B339Q
More data for this
Ligand-Target Pair
Estrogen receptor


(Homo sapiens (Human))		BDBM50532106
PNG
(CHEMBL4539802)
Show SMILES Oc1ccc2C3=C(C(Oc2c1)c1ccc(OCCN2CC[C@@H](CF)C2)cc1)c1ccc(O)cc1OCC3 |r,c:5|
Show InChI InChI=1S/C30H30FNO5/c31-17-19-9-11-32(18-19)12-14-35-23-5-1-20(2-6-23)30-29-25(24-7-3-22(34)16-28(24)37-30)10-13-36-27-15-21(33)4-8-26(27)29/h1-8,15-16,19,30,33-34H,9-14,17-18H2/t19-,30?/m0/s1
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n/an/a 0.0760n/an/an/an/an/an/a



Genentech Inc.

Curated by ChEMBL


Assay Description
Induction of ERalpha degradation in human MCF7 cells after 4 hrs by Alexafluor-488 conjugate anti-mouse IgG antibody/Hoechst 33342 staining based imm...

Bioorg Med Chem Lett 29: 905-911 (2019)


Article DOI: 10.1016/j.bmcl.2019.01.036
BindingDB Entry DOI: 10.7270/Q2Q52T3W
More data for this
Ligand-Target Pair
Estrogen receptor


(Homo sapiens (Human))		BDBM50532104
PNG
(CHEMBL1087419)
Show SMILES Oc1ccc2C3=C(C(Oc2c1)c1ccc(OCCN2CCCCC2)cc1)c1ccc(O)cc1OCC3 |c:5|
Show InChI InChI=1S/C30H31NO5/c32-21-7-11-26-27(18-21)35-16-12-25-24-10-6-22(33)19-28(24)36-30(29(25)26)20-4-8-23(9-5-20)34-17-15-31-13-2-1-3-14-31/h4-11,18-19,30,32-33H,1-3,12-17H2
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n/an/a 0.280n/an/an/an/an/an/a



Genentech Inc.

Curated by ChEMBL


Assay Description
Induction of ERalpha degradation in human MCF7 cells after 4 hrs by Alexafluor-488 conjugate anti-mouse IgG antibody/Hoechst 33342 staining based imm...

Bioorg Med Chem Lett 29: 905-911 (2019)


Article DOI: 10.1016/j.bmcl.2019.01.036
BindingDB Entry DOI: 10.7270/Q2Q52T3W
More data for this
Ligand-Target Pair
Glucocorticoid receptor


(Homo sapiens (Human))		BDBM50206947
PNG
(CHEMBL3966490)
Show SMILES [H][C@@]12CC[C@@](O)(C#CC)[C@@]1(C)C[C@H](OCc1ccccc1)[C@]1([H])c3ccc(cc3CC[C@@]21[H])C(=O)Nc1cccnc1C |r|
Show InChI InChI=1S/C35H38N2O3/c1-4-17-35(39)18-16-29-28-15-12-25-20-26(33(38)37-30-11-8-19-36-23(30)2)13-14-27(25)32(28)31(21-34(29,35)3)40-22-24-9-6-5-7-10-24/h5-11,13-14,19-20,28-29,31-32,39H,12,15-16,18,21-22H2,1-3H3,(H,37,38)/t28-,29-,31-,32+,34-,35-/m0/s1
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n/an/a 0.400n/an/an/an/an/an/a



The Scripps Research Institute

Curated by ChEMBL


Assay Description
Antagonist activity at GR in human HepG2 cells assessed as inhibition of protein mediated-transcriptional activity by MMTV-promoter driven luciferase...

Bioorg Med Chem Lett 27: 347-353 (2017)


Article DOI: 10.1016/j.bmcl.2016.11.007
BindingDB Entry DOI: 10.7270/Q24B339Q
More data for this
Ligand-Target Pair
Glucocorticoid receptor


(Homo sapiens (Human))		BDBM50206952
PNG
(CHEMBL3907029)
Show SMILES [H][C@@]12CC[C@@](O)(C#CC)[C@@]1(C)C[C@H](OCc1cccc(Cl)c1)[C@]1([H])c3ccc(cc3CC[C@@]21[H])C(=O)Nc1cccnc1C |r|
Show InChI InChI=1S/C35H37ClN2O3/c1-4-15-35(40)16-14-29-28-13-10-24-19-25(33(39)38-30-9-6-17-37-22(30)2)11-12-27(24)32(28)31(20-34(29,35)3)41-21-23-7-5-8-26(36)18-23/h5-9,11-12,17-19,28-29,31-32,40H,10,13-14,16,20-21H2,1-3H3,(H,38,39)/t28-,29-,31-,32+,34-,35-/m0/s1
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n/an/a 0.900n/an/an/an/an/an/a



The Scripps Research Institute

Curated by ChEMBL


Assay Description
Antagonist activity at GR in human HepG2 cells assessed as inhibition of protein mediated-transcriptional activity by MMTV-promoter driven luciferase...

Bioorg Med Chem Lett 27: 347-353 (2017)


Article DOI: 10.1016/j.bmcl.2016.11.007
BindingDB Entry DOI: 10.7270/Q24B339Q
More data for this
Ligand-Target Pair
Glucocorticoid receptor


(Homo sapiens (Human))		BDBM50206951
PNG
(CHEMBL3904106)
Show SMILES [H][C@@]12CC[C@@](O)(C#CC)[C@@]1(C)C[C@H](OCc1ccccc1Cl)[C@]1([H])c3ccc(cc3CC[C@@]21[H])C(=O)Nc1cccnc1C |r|
Show InChI InChI=1S/C35H37ClN2O3/c1-4-16-35(40)17-15-28-27-14-11-23-19-24(33(39)38-30-10-7-18-37-22(30)2)12-13-26(23)32(27)31(20-34(28,35)3)41-21-25-8-5-6-9-29(25)36/h5-10,12-13,18-19,27-28,31-32,40H,11,14-15,17,20-21H2,1-3H3,(H,38,39)/t27-,28-,31-,32+,34-,35-/m0/s1
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n/an/a 1.40n/an/an/an/an/an/a



The Scripps Research Institute

Curated by ChEMBL


Assay Description
Antagonist activity at GR in human HepG2 cells assessed as inhibition of protein mediated-transcriptional activity by MMTV-promoter driven luciferase...

Bioorg Med Chem Lett 27: 347-353 (2017)


Article DOI: 10.1016/j.bmcl.2016.11.007
BindingDB Entry DOI: 10.7270/Q24B339Q
More data for this
Ligand-Target Pair
Estrogen receptor


(Homo sapiens (Human))		BDBM50532099
PNG
(CHEMBL4443826)
Show SMILES Oc1ccc2OC(C3=C(CCOc4ccc(O)cc34)c2c1)c1ccc(OCCN2CC(CF)C2)cc1 |t:7|
Show InChI InChI=1S/C29H28FNO5/c30-15-18-16-31(17-18)10-12-34-22-5-1-19(2-6-22)29-28-23(24-13-20(32)4-8-27(24)36-29)9-11-35-26-7-3-21(33)14-25(26)28/h1-8,13-14,18,29,32-33H,9-12,15-17H2
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n/an/a 3.20n/an/an/an/an/an/a



Genentech Inc.

Curated by ChEMBL


Assay Description
Induction of ERalpha degradation in human MCF7 cells after 4 hrs by Alexafluor-488 conjugate anti-mouse IgG antibody/Hoechst 33342 staining based imm...

Bioorg Med Chem Lett 29: 905-911 (2019)


Article DOI: 10.1016/j.bmcl.2019.01.036
BindingDB Entry DOI: 10.7270/Q2Q52T3W
More data for this
Ligand-Target Pair
Estrogen receptor


(Homo sapiens (Human))		BDBM50532099
PNG
(CHEMBL4443826)
Show SMILES Oc1ccc2OC(C3=C(CCOc4ccc(O)cc34)c2c1)c1ccc(OCCN2CC(CF)C2)cc1 |t:7|
Show InChI InChI=1S/C29H28FNO5/c30-15-18-16-31(17-18)10-12-34-22-5-1-19(2-6-22)29-28-23(24-13-20(32)4-8-27(24)36-29)9-11-35-26-7-3-21(33)14-25(26)28/h1-8,13-14,18,29,32-33H,9-12,15-17H2
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n/an/a 3.20n/an/an/an/an/an/a



Genentech Inc.

Curated by ChEMBL


Assay Description
Induction of ERalpha degradation in human MCF7 cells after 4 hrs by Alexafluor-488 conjugate anti-mouse IgG antibody/Hoechst 33342 staining based imm...

Bioorg Med Chem Lett 29: 905-911 (2019)


Article DOI: 10.1016/j.bmcl.2019.01.036
BindingDB Entry DOI: 10.7270/Q2Q52T3W
More data for this
Ligand-Target Pair
Histone deacetylase 6


(Homo sapiens (Human))		BDBM50570668
PNG
(CHEMBL4862510)
Show SMILES NC(=O)c1ccc2Sc3ccccc3N(Cc3ccc(cc3)C(=O)NO)c2c1
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MMDB

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n/an/a 4.60n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of N-terminal GST-tagged full length human HDAC6 expressed in baculovirus-infected Sf9 cells using Boc-Lys (acetyl)-AMC as substrate prein...

Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113419
BindingDB Entry DOI: 10.7270/Q2ST7TN4
More data for this
Ligand-Target Pair
Estrogen receptor beta


(Homo sapiens (Human))		BDBM50005596
PNG
(CHEMBL3234622)
Show SMILES [#8]-c1ccc(cc1)-[#6](=[#7]/c1ccc(Br)cc1)\c1ccc(-[#8])cc1
Show InChI InChI=1S/C19H14BrNO2/c20-15-5-7-16(8-6-15)21-19(13-1-9-17(22)10-2-13)14-3-11-18(23)12-4-14/h1-12,22-23H
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n/an/a 6n/an/an/an/an/an/a



Key Laboratory of Combinatorial Biosynthesis and Drug Discovery (Wuhan University)

Curated by ChEMBL


Assay Description
Antagonist activity at ERbeta (unknown origin) expressed in human HepG2 cells assessed as inhibition of 17beta-estradiol-induced transcriptional acti...

J Med Chem 57: 3532-45 (2014)


Article DOI: 10.1021/jm500268j
BindingDB Entry DOI: 10.7270/Q2MS3V9N
More data for this
Ligand-Target Pair
Estrogen receptor beta


(Homo sapiens (Human))		BDBM50005603
PNG
(CHEMBL3234630)
Show SMILES Oc1ccc(cc1)C(=N/c1ccccc1Cl)\c1ccc(O)cc1O
Show InChI InChI=1S/C19H14ClNO3/c20-16-3-1-2-4-17(16)21-19(12-5-7-13(22)8-6-12)15-10-9-14(23)11-18(15)24/h1-11,22-24H/b21-19+
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n/an/a 6n/an/an/an/an/an/a



Key Laboratory of Combinatorial Biosynthesis and Drug Discovery (Wuhan University)

Curated by ChEMBL


Assay Description
Antagonist activity at ERbeta (unknown origin) expressed in human HepG2 cells assessed as inhibition of 17beta-estradiol-induced transcriptional acti...

J Med Chem 57: 3532-45 (2014)


Article DOI: 10.1021/jm500268j
BindingDB Entry DOI: 10.7270/Q2MS3V9N
More data for this
Ligand-Target Pair
Estrogen receptor beta


(Homo sapiens (Human))		BDBM50005598
PNG
(CHEMBL3234626)
Show SMILES Oc1ccc(cc1)C(=N/c1ccccc1)\c1ccc(O)cc1O
Show InChI InChI=1S/C19H15NO3/c21-15-8-6-13(7-9-15)19(20-14-4-2-1-3-5-14)17-11-10-16(22)12-18(17)23/h1-12,21-23H/b20-19+
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n/an/a 6n/an/an/an/an/an/a



Key Laboratory of Combinatorial Biosynthesis and Drug Discovery (Wuhan University)

Curated by ChEMBL


Assay Description
Antagonist activity at ERbeta (unknown origin) expressed in human HepG2 cells assessed as inhibition of 17beta-estradiol-induced transcriptional acti...

J Med Chem 57: 3532-45 (2014)


Article DOI: 10.1021/jm500268j
BindingDB Entry DOI: 10.7270/Q2MS3V9N
More data for this
Ligand-Target Pair
Estrogen receptor beta


(Homo sapiens (Human))		BDBM50005588
PNG
(CHEMBL140411 | CHEMBL3234614)
Show SMILES [#6]-c1ccccc1\[#7]=[#6](/c1ccc(-[#8])cc1)-c1ccc(-[#8])cc1
Show InChI InChI=1S/C20H17NO2/c1-14-4-2-3-5-19(14)21-20(15-6-10-17(22)11-7-15)16-8-12-18(23)13-9-16/h2-13,22-23H,1H3
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n/an/a 6n/an/an/an/an/an/a



Key Laboratory of Combinatorial Biosynthesis and Drug Discovery (Wuhan University)

Curated by ChEMBL


Assay Description
Antagonist activity at ERbeta (unknown origin) expressed in human HepG2 cells assessed as inhibition of 17beta-estradiol-induced transcriptional acti...

J Med Chem 57: 3532-45 (2014)


Article DOI: 10.1021/jm500268j
BindingDB Entry DOI: 10.7270/Q2MS3V9N
More data for this
Ligand-Target Pair
Eukaryotic translation initiation factor 2-alpha kinase 1


(Homo sapiens (Human))		BDBM50414894
PNG
(CHEMBL573760)
Show SMILES COc1cc2C(=O)c3c(NCc4c(Cl)cccc4Cl)[nH]nc3-c2cc1OC
Show InChI InChI=1S/C19H15Cl2N3O3/c1-26-14-6-9-10(7-15(14)27-2)18(25)16-17(9)23-24-19(16)22-8-11-12(20)4-3-5-13(11)21/h3-7H,8H2,1-2H3,(H2,22,23,24)
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n/an/a 6.31n/an/an/an/an/an/a



Johnson& Johnson Pharmaceutical Research and Development

Curated by ChEMBL


Assay Description
Inhibition of human HRI kinase

Bioorg Med Chem Lett 19: 6548-51 (2009)


Article DOI: 10.1016/j.bmcl.2009.10.033
BindingDB Entry DOI: 10.7270/Q26Q1ZGZ
More data for this
Ligand-Target Pair
Estrogen receptor beta


(Homo sapiens (Human))		BDBM50005595
PNG
(CHEMBL3234621)
Show SMILES [#8]-c1ccc(cc1)-[#6](=[#7]/c1ccc(F)cc1)\c1ccc(-[#8])cc1
Show InChI InChI=1S/C19H14FNO2/c20-15-5-7-16(8-6-15)21-19(13-1-9-17(22)10-2-13)14-3-11-18(23)12-4-14/h1-12,22-23H
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n/an/a 7n/an/an/an/an/an/a



Key Laboratory of Combinatorial Biosynthesis and Drug Discovery (Wuhan University)

Curated by ChEMBL


Assay Description
Antagonist activity at ERbeta (unknown origin) expressed in human HepG2 cells assessed as inhibition of 17beta-estradiol-induced transcriptional acti...

J Med Chem 57: 3532-45 (2014)


Article DOI: 10.1021/jm500268j
BindingDB Entry DOI: 10.7270/Q2MS3V9N
More data for this
Ligand-Target Pair
Histone deacetylase 6


(Homo sapiens (Human))		BDBM50517568
PNG
(CHEMBL4438566)
Show SMILES ONC(=O)c1ccc(CN2c3ccccc3Sc3ccccc23)cc1
Show InChI InChI=1S/C20H16N2O2S/c23-20(21-24)15-11-9-14(10-12-15)13-22-16-5-1-3-7-18(16)25-19-8-4-2-6-17(19)22/h1-12,24H,13H2,(H,21,23)
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n/an/a 7.60n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of N-terminal GST-tagged full length human HDAC6 expressed in baculovirus-infected Sf9 cells using Boc-Lys (acetyl)-AMC as substrate prein...

Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113419
BindingDB Entry DOI: 10.7270/Q2ST7TN4
More data for this
Ligand-Target Pair
Eukaryotic translation initiation factor 2-alpha kinase 1


(Homo sapiens (Human))		BDBM50414893
PNG
(CHEMBL578426)
Show SMILES COc1cc2Cc3c(NCc4c(C)cccc4C)[nH]nc3-c2cc1OC
Show InChI InChI=1S/C21H23N3O2/c1-12-6-5-7-13(2)17(12)11-22-21-16-8-14-9-18(25-3)19(26-4)10-15(14)20(16)23-24-21/h5-7,9-10H,8,11H2,1-4H3,(H2,22,23,24)
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n/an/a 7.94n/an/an/an/an/an/a



Johnson& Johnson Pharmaceutical Research and Development

Curated by ChEMBL


Assay Description
Inhibition of human HRI kinase

Bioorg Med Chem Lett 19: 6548-51 (2009)


Article DOI: 10.1016/j.bmcl.2009.10.033
BindingDB Entry DOI: 10.7270/Q26Q1ZGZ
More data for this
Ligand-Target Pair
Estrogen receptor beta


(Homo sapiens (Human))		BDBM50005593
PNG
(CHEMBL3234619)
Show SMILES [#8]-c1ccc(cc1)-[#6](=[#7]/c1ccc(Cl)cc1)\c1ccc(-[#8])cc1
Show InChI InChI=1S/C19H14ClNO2/c20-15-5-7-16(8-6-15)21-19(13-1-9-17(22)10-2-13)14-3-11-18(23)12-4-14/h1-12,22-23H
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n/an/a 9n/an/an/an/an/an/a



Key Laboratory of Combinatorial Biosynthesis and Drug Discovery (Wuhan University)

Curated by ChEMBL


Assay Description
Antagonist activity at ERbeta (unknown origin) expressed in human HepG2 cells assessed as inhibition of 17beta-estradiol-induced transcriptional acti...

J Med Chem 57: 3532-45 (2014)


Article DOI: 10.1021/jm500268j
BindingDB Entry DOI: 10.7270/Q2MS3V9N
More data for this
Ligand-Target Pair
Histone deacetylase 6


(Homo sapiens (Human))		BDBM50570667
PNG
(CHEMBL4877300)
Show SMILES CSc1ccc2Sc3ccccc3N(Cc3ccc(cc3)C(=O)NO)c2c1
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n/an/a 9.40n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of N-terminal GST-tagged full length human HDAC6 expressed in baculovirus-infected Sf9 cells using Boc-Lys (acetyl)-AMC as substrate prein...

Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113419
BindingDB Entry DOI: 10.7270/Q2ST7TN4
More data for this
Ligand-Target Pair
Histone deacetylase 6


(Homo sapiens (Human))		BDBM50517570
PNG
(CHEMBL4530950)
Show SMILES ONC(=O)c1ccc(CN2c3ccccc3Sc3ccc(Cl)cc23)cc1
Show InChI InChI=1S/C20H15ClN2O2S/c21-15-9-10-19-17(11-15)23(16-3-1-2-4-18(16)26-19)12-13-5-7-14(8-6-13)20(24)22-25/h1-11,25H,12H2,(H,22,24)
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n/an/a 9.5n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of N-terminal GST-tagged full length human HDAC6 expressed in baculovirus-infected Sf9 cells using Boc-Lys (acetyl)-AMC as substrate prein...

Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113419
BindingDB Entry DOI: 10.7270/Q2ST7TN4
More data for this
Ligand-Target Pair
Estrogen receptor


(Homo sapiens (Human))		BDBM50532100
PNG
(CHEMBL4464146)
Show SMILES Oc1ccc2C3=C(C(Oc2c1)c1ccc(OCCN2CC(CF)C2)cc1)c1cc(O)ccc1OCC3 |c:5|
Show InChI InChI=1S/C29H28FNO5/c30-15-18-16-31(17-18)10-12-34-22-5-1-19(2-6-22)29-28-24(23-7-3-21(33)14-27(23)36-29)9-11-35-26-8-4-20(32)13-25(26)28/h1-8,13-14,18,29,32-33H,9-12,15-17H2
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n/an/a 9.60n/an/an/an/an/an/a



Genentech Inc.

Curated by ChEMBL


Assay Description
Induction of ERalpha degradation in human MCF7 cells after 4 hrs by Alexafluor-488 conjugate anti-mouse IgG antibody/Hoechst 33342 staining based imm...

Bioorg Med Chem Lett 29: 905-911 (2019)


Article DOI: 10.1016/j.bmcl.2019.01.036
BindingDB Entry DOI: 10.7270/Q2Q52T3W
More data for this
Ligand-Target Pair
Estrogen receptor


(Homo sapiens (Human))		BDBM50532100
PNG
(CHEMBL4464146)
Show SMILES Oc1ccc2C3=C(C(Oc2c1)c1ccc(OCCN2CC(CF)C2)cc1)c1cc(O)ccc1OCC3 |c:5|
Show InChI InChI=1S/C29H28FNO5/c30-15-18-16-31(17-18)10-12-34-22-5-1-19(2-6-22)29-28-24(23-7-3-21(33)14-27(23)36-29)9-11-35-26-8-4-20(32)13-25(26)28/h1-8,13-14,18,29,32-33H,9-12,15-17H2
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n/an/a 9.60n/an/an/an/an/an/a



Genentech Inc.

Curated by ChEMBL


Assay Description
Induction of ERalpha degradation in human MCF7 cells after 4 hrs by Alexafluor-488 conjugate anti-mouse IgG antibody/Hoechst 33342 staining based imm...

Bioorg Med Chem Lett 29: 905-911 (2019)


Article DOI: 10.1016/j.bmcl.2019.01.036
BindingDB Entry DOI: 10.7270/Q2Q52T3W
More data for this
Ligand-Target Pair
Histone deacetylase 6


(Homo sapiens (Human))		BDBM50570670
PNG
(CHEMBL4874671)
Show SMILES ONC(=O)c1ccc(CN2c3ccccc3[S+]([O-])c3ccc(Cl)cc23)cc1
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n/an/a 9.80n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of N-terminal GST-tagged full length human HDAC6 expressed in baculovirus-infected Sf9 cells using Boc-Lys (acetyl)-AMC as substrate prein...

Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113419
BindingDB Entry DOI: 10.7270/Q2ST7TN4
More data for this
Ligand-Target Pair
Histone deacetylase 6


(Homo sapiens (Human))		BDBM50570669
PNG
(CHEMBL4877805)
Show SMILES C\C(=N/O)c1ccc2Sc3ccccc3N(Cc3ccc(cc3)C(=O)NO)c2c1
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n/an/a 11n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of N-terminal GST-tagged full length human HDAC6 expressed in baculovirus-infected Sf9 cells using Boc-Lys (acetyl)-AMC as substrate prein...

Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113419
BindingDB Entry DOI: 10.7270/Q2ST7TN4
More data for this
Ligand-Target Pair
Histone deacetylase 6


(Homo sapiens (Human))		BDBM19149
PNG
(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Show SMILES ONC(=O)CCCCCCC(=O)Nc1ccccc1
Show InChI InChI=1S/C14H20N2O3/c17-13(15-12-8-4-3-5-9-12)10-6-1-2-7-11-14(18)16-19/h3-5,8-9,19H,1-2,6-7,10-11H2,(H,15,17)(H,16,18)
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n/an/a 13n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of N-terminal GST-tagged full length human HDAC6 expressed in baculovirus-infected Sf9 cells using Boc-Lys (acetyl)-AMC as substrate prein...

Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113419
BindingDB Entry DOI: 10.7270/Q2ST7TN4
More data for this
Ligand-Target Pair
Estrogen receptor beta


(Homo sapiens (Human))		BDBM50005587
PNG
(CHEMBL138420 | CHEMBL3234612)
Show SMILES [#8]-c1ccc(cc1)-[#6](=[#7]/c1ccccc1)\c1ccc(-[#8])cc1
Show InChI InChI=1S/C19H15NO2/c21-17-10-6-14(7-11-17)19(15-8-12-18(22)13-9-15)20-16-4-2-1-3-5-16/h1-13,21-22H
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n/an/a 13n/an/an/an/an/an/a



Key Laboratory of Combinatorial Biosynthesis and Drug Discovery (Wuhan University)

Curated by ChEMBL


Assay Description
Antagonist activity at ERbeta (unknown origin) expressed in human HepG2 cells assessed as inhibition of 17beta-estradiol-induced transcriptional acti...

J Med Chem 57: 3532-45 (2014)


Article DOI: 10.1021/jm500268j
BindingDB Entry DOI: 10.7270/Q2MS3V9N
More data for this
Ligand-Target Pair
Histone deacetylase 6


(Homo sapiens (Human))		BDBM50570674
PNG
(CHEMBL4847771)
Show SMILES NC(=O)c1ccc2[S+]([O-])c3ccccc3N(Cc3ccc(cc3)C(=O)NO)c2c1
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n/an/a 14n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of N-terminal GST-tagged full length human HDAC6 expressed in baculovirus-infected Sf9 cells using Boc-Lys (acetyl)-AMC as substrate prein...

Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113419
BindingDB Entry DOI: 10.7270/Q2ST7TN4
More data for this
Ligand-Target Pair
Histone deacetylase 6


(Homo sapiens (Human))		BDBM50517565
PNG
(CHEMBL4472834)
Show SMILES ONC(=O)c1ccc(CN2c3ccccc3Sc3ccc(cc23)C(F)(F)F)cc1
Show InChI InChI=1S/C21H15F3N2O2S/c22-21(23,24)15-9-10-19-17(11-15)26(16-3-1-2-4-18(16)29-19)12-13-5-7-14(8-6-13)20(27)25-28/h1-11,28H,12H2,(H,25,27)
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n/an/a 14n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of N-terminal GST-tagged full length human HDAC6 expressed in baculovirus-infected Sf9 cells using Boc-Lys (acetyl)-AMC as substrate prein...

Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113419
BindingDB Entry DOI: 10.7270/Q2ST7TN4
More data for this
Ligand-Target Pair
Estrogen receptor beta


(Homo sapiens (Human))		BDBM50005592
PNG
(CHEMBL139628 | CHEMBL3234618)
Show SMILES [#8]-c1ccc(cc1)-[#6](=[#7]/c1cccc(Cl)c1)\c1ccc(-[#8])cc1
Show InChI InChI=1S/C19H14ClNO2/c20-15-2-1-3-16(12-15)21-19(13-4-8-17(22)9-5-13)14-6-10-18(23)11-7-14/h1-12,22-23H
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n/an/a 16n/an/an/an/an/an/a



Key Laboratory of Combinatorial Biosynthesis and Drug Discovery (Wuhan University)

Curated by ChEMBL


Assay Description
Antagonist activity at ERbeta (unknown origin) expressed in human HepG2 cells assessed as inhibition of 17beta-estradiol-induced transcriptional acti...

J Med Chem 57: 3532-45 (2014)


Article DOI: 10.1021/jm500268j
BindingDB Entry DOI: 10.7270/Q2MS3V9N
More data for this
Ligand-Target Pair
Histone deacetylase 6


(Homo sapiens (Human))		BDBM50570675
PNG
(CHEMBL4846564)
Show SMILES C\C(=N/O)c1ccc2[S+]([O-])c3ccccc3N(Cc3ccc(cc3)C(=O)NO)c2c1
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n/an/a 16n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of N-terminal GST-tagged full length human HDAC6 expressed in baculovirus-infected Sf9 cells using Boc-Lys (acetyl)-AMC as substrate prein...

Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113419
BindingDB Entry DOI: 10.7270/Q2ST7TN4
More data for this
Ligand-Target Pair
Estrogen receptor beta


(Homo sapiens (Human))		BDBM50005599
PNG
(CHEMBL3234627)
Show SMILES Cc1ccccc1\N=C(/c1ccc(O)cc1)c1ccc(O)cc1O
Show InChI InChI=1S/C20H17NO3/c1-13-4-2-3-5-18(13)21-20(14-6-8-15(22)9-7-14)17-11-10-16(23)12-19(17)24/h2-12,22-24H,1H3/b21-20+
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n/an/a 16n/an/an/an/an/an/a



Key Laboratory of Combinatorial Biosynthesis and Drug Discovery (Wuhan University)

Curated by ChEMBL


Assay Description
Antagonist activity at ERbeta (unknown origin) expressed in human HepG2 cells assessed as inhibition of 17beta-estradiol-induced transcriptional acti...

J Med Chem 57: 3532-45 (2014)


Article DOI: 10.1021/jm500268j
BindingDB Entry DOI: 10.7270/Q2MS3V9N
More data for this
Ligand-Target Pair
Histone deacetylase 6


(Homo sapiens (Human))		BDBM50517567
PNG
(CHEMBL4545246)
Show SMILES COc1ccc2Sc3ccccc3N(Cc3ccc(cc3)C(=O)NO)c2c1
Show InChI InChI=1S/C21H18N2O3S/c1-26-16-10-11-20-18(12-16)23(17-4-2-3-5-19(17)27-20)13-14-6-8-15(9-7-14)21(24)22-25/h2-12,25H,13H2,1H3,(H,22,24)
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n/an/a 19n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of N-terminal GST-tagged full length human HDAC6 expressed in baculovirus-infected Sf9 cells using Boc-Lys (acetyl)-AMC as substrate prein...

Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113419
BindingDB Entry DOI: 10.7270/Q2ST7TN4
More data for this
Ligand-Target Pair
Estrogen receptor beta


(Homo sapiens (Human))		BDBM50005591
PNG
(CHEMBL141807 | CHEMBL3234617)
Show SMILES [#8]-c1ccc(cc1)-[#6](=[#7]/c1ccccc1Cl)\c1ccc(-[#8])cc1
Show InChI InChI=1S/C19H14ClNO2/c20-17-3-1-2-4-18(17)21-19(13-5-9-15(22)10-6-13)14-7-11-16(23)12-8-14/h1-12,22-23H
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Key Laboratory of Combinatorial Biosynthesis and Drug Discovery (Wuhan University)

Curated by ChEMBL


Assay Description
Antagonist activity at ERbeta (unknown origin) expressed in human HepG2 cells assessed as inhibition of 17beta-estradiol-induced transcriptional acti...

J Med Chem 57: 3532-45 (2014)


Article DOI: 10.1021/jm500268j
BindingDB Entry DOI: 10.7270/Q2MS3V9N
More data for this
Ligand-Target Pair
Histone deacetylase 6


(Homo sapiens (Human))		BDBM50570671
PNG
(CHEMBL4877023)
Show SMILES ONC(=O)c1ccc(CN2c3ccccc3[S+]([O-])c3ccc(cc23)C(F)(F)F)cc1
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TBA

Assay Description
Inhibition of N-terminal GST-tagged full length human HDAC6 expressed in baculovirus-infected Sf9 cells using Boc-Lys (acetyl)-AMC as substrate prein...

Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113419
BindingDB Entry DOI: 10.7270/Q2ST7TN4
More data for this
Ligand-Target Pair
Eukaryotic translation initiation factor 2-alpha kinase 1


(Homo sapiens (Human))		BDBM50414892
PNG
(CHEMBL576168)
Show SMILES COc1cc2Cc3c(NCc4c(C)cccc4Cl)[nH]nc3-c2cc1OC
Show InChI InChI=1S/C20H20ClN3O2/c1-11-5-4-6-16(21)15(11)10-22-20-14-7-12-8-17(25-2)18(26-3)9-13(12)19(14)23-24-20/h4-6,8-9H,7,10H2,1-3H3,(H2,22,23,24)
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Johnson& Johnson Pharmaceutical Research and Development

Curated by ChEMBL


Assay Description
Inhibition of human HRI kinase

Bioorg Med Chem Lett 19: 6548-51 (2009)


Article DOI: 10.1016/j.bmcl.2009.10.033
BindingDB Entry DOI: 10.7270/Q26Q1ZGZ
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (Human))		BDBM50570676
PNG
(CHEMBL4859992)
Show SMILES NC(=O)c1ccc2Sc3ccccc3N(Cc3ccc(\C=C\C(=O)NO)cc3)c2c1
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n/an/a 20n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of HDAC in human HeLa nuclear extracts using Boc-Lys (acetyl)-AMC as substrate preincubated for 5 mins followed by substrate addition and ...

Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113419
BindingDB Entry DOI: 10.7270/Q2ST7TN4
More data for this
Ligand-Target Pair
Histone deacetylase 6


(Homo sapiens (Human))		BDBM50517575
PNG
(CHEMBL4473451)
Show SMILES ONC(=O)c1ccc(CN2c3ccccc3[S+]([O-])c3ccccc23)cc1
Show InChI InChI=1S/C20H16N2O3S/c23-20(21-24)15-11-9-14(10-12-15)13-22-16-5-1-3-7-18(16)26(25)19-8-4-2-6-17(19)22/h1-12,24H,13H2,(H,21,23)
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n/an/a 21n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of N-terminal GST-tagged full length human HDAC6 expressed in baculovirus-infected Sf9 cells using Boc-Lys (acetyl)-AMC as substrate prein...

Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113419
BindingDB Entry DOI: 10.7270/Q2ST7TN4
More data for this
Ligand-Target Pair
Estrogen receptor beta


(Homo sapiens (Human))		BDBM50005594
PNG
(CHEMBL3234620)
Show SMILES [#8]-c1ccc(cc1)-[#6](=[#7]/c1cccc(c1)C(F)(F)F)\c1ccc(-[#8])cc1
Show InChI InChI=1S/C20H14F3NO2/c21-20(22,23)15-2-1-3-16(12-15)24-19(13-4-8-17(25)9-5-13)14-6-10-18(26)11-7-14/h1-12,25-26H
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Key Laboratory of Combinatorial Biosynthesis and Drug Discovery (Wuhan University)

Curated by ChEMBL


Assay Description
Antagonist activity at ERbeta (unknown origin) expressed in human HepG2 cells assessed as inhibition of 17beta-estradiol-induced transcriptional acti...

J Med Chem 57: 3532-45 (2014)


Article DOI: 10.1021/jm500268j
BindingDB Entry DOI: 10.7270/Q2MS3V9N
More data for this
Ligand-Target Pair
Histone deacetylase 1


(Homo sapiens (Human))		BDBM19149
PNG
(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Show SMILES ONC(=O)CCCCCCC(=O)Nc1ccccc1
Show InChI InChI=1S/C14H20N2O3/c17-13(15-12-8-4-3-5-9-12)10-6-1-2-7-11-14(18)16-19/h3-5,8-9,19H,1-2,6-7,10-11H2,(H,15,17)(H,16,18)
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n/an/a 25n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of recombinant human C-terminal FLAG/His-tagged HDAC1 (1 to 482 residues) expressed in Sf9 insect cells using fluor de lys SIRT1 as substr...

Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112193
BindingDB Entry DOI: 10.7270/Q2FX7F3B
More data for this
Ligand-Target Pair		3D
3D Structure (crystal)
Histone deacetylase 6


(Homo sapiens (Human))		BDBM50551540
PNG
(CHEMBL4762873)
Show SMILES ONC(=O)c1ccc(Nc2c3ccccc3nc3ccccc23)cc1
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n/an/a 25n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of recombinant human full-length N-terminal GST-tagged HDAC6 expressed in baculovirus infected Sf9 insect cells using Boc-Lys(Ac)-AMC as s...

Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112193
BindingDB Entry DOI: 10.7270/Q2FX7F3B
More data for this
Ligand-Target Pair
Histone deacetylase 6


(Homo sapiens (Human))		BDBM50551544
PNG
(CHEMBL4796066)
Show SMILES ONC(=O)c1ccc(Nc2c3ccccc3nc3ccc(Br)cc23)cc1
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n/an/a 26n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of N-terminal GST-tagged full length human HDAC6 expressed in baculovirus-infected Sf9 cells using Boc-Lys (acetyl)-AMC as substrate prein...

Citation and Details

Article DOI: 10.1016/j.ejmech.2021.113419
BindingDB Entry DOI: 10.7270/Q2ST7TN4
More data for this
Ligand-Target Pair
Histone deacetylase 6


(Homo sapiens (Human))		BDBM50551544
PNG
(CHEMBL4796066)
Show SMILES ONC(=O)c1ccc(Nc2c3ccccc3nc3ccc(Br)cc23)cc1
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n/an/a 26n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of recombinant human full-length N-terminal GST-tagged HDAC6 expressed in baculovirus infected Sf9 insect cells using Boc-Lys(Ac)-AMC as s...

Citation and Details

Article DOI: 10.1016/j.ejmech.2020.112193
BindingDB Entry DOI: 10.7270/Q2FX7F3B
More data for this
Ligand-Target Pair
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