Found 1015 hits with Last Name = 'das' and Initial = 'c' Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Beta-2 adrenergic receptor
(Homo sapiens (Human)) | BDBM50379086
(CHEMBL2012521 | CHEMBL2012522 | LY-377604)Show SMILES CC(C)(Cc1ccc(Oc2ccc(cn2)C(N)=O)cc1)NC[C@H](O)COc1cccc2[nH]c3ccccc3c12 |r| Show InChI InChI=1S/C31H32N4O4/c1-31(2,16-20-10-13-23(14-11-20)39-28-15-12-21(17-33-28)30(32)37)34-18-22(36)19-38-27-9-5-8-26-29(27)24-6-3-4-7-25(24)35-26/h3-15,17,22,34-36H,16,18-19H2,1-2H3,(H2,32,37)/t22-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid UniChem
Similars
| Article PubMed
| 0.0120 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Displacement of [125I]Iodocyanopindolol from human adrenergic beta2 receptor expressed in insect sf9 cells by scintillation counting |
ACS Med Chem Lett 2: 583-586 (2011)
Article DOI: 10.1021/ml200071k BindingDB Entry DOI: 10.7270/Q20R9QDP |
More data for this Ligand-Target Pair | |
Beta-1 adrenergic receptor
(Homo sapiens (Human)) | BDBM50379086
(CHEMBL2012521 | CHEMBL2012522 | LY-377604)Show SMILES CC(C)(Cc1ccc(Oc2ccc(cn2)C(N)=O)cc1)NC[C@H](O)COc1cccc2[nH]c3ccccc3c12 |r| Show InChI InChI=1S/C31H32N4O4/c1-31(2,16-20-10-13-23(14-11-20)39-28-15-12-21(17-33-28)30(32)37)34-18-22(36)19-38-27-9-5-8-26-29(27)24-6-3-4-7-25(24)35-26/h3-15,17,22,34-36H,16,18-19H2,1-2H3,(H2,32,37)/t22-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid UniChem
Similars
| Article PubMed
| 0.0230 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Displacement of [125I]Iodocyanopindolol from human adrenergic beta1 receptor expressed in insect sf9 cells by scintillation counting |
ACS Med Chem Lett 2: 583-586 (2011)
Article DOI: 10.1021/ml200071k BindingDB Entry DOI: 10.7270/Q20R9QDP |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50186291
(2-isopropyl-7-(3-(piperidin-1-yl)propoxy)-1,2,3,4-...)Show InChI InChI=1S/C20H32N2O/c1-17(2)22-13-9-18-7-8-20(15-19(18)16-22)23-14-6-12-21-10-4-3-5-11-21/h7-8,15,17H,3-6,9-14,16H2,1-2H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 0.170 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description Displacement of [3H]N-alpha-methylhistamine from human cloned H3 receptor |
Bioorg Med Chem Lett 16: 3415-8 (2006)
Article DOI: 10.1016/j.bmcl.2006.04.004 BindingDB Entry DOI: 10.7270/Q2WM1D07 |
More data for this Ligand-Target Pair | |
Dipeptidyl peptidase 4
(Homo sapiens (Human)) | BDBM50050513
((R)-1-((S)-2-amino-3-methylbutanoyl)pyrrolidin-2-y...)Show InChI InChI=1S/C9H19BN2O3/c1-6(2)8(11)9(13)12-5-3-4-7(12)10(14)15/h6-8,14-15H,3-5,11H2,1-2H3/t7-,8-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 0.180 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.bmc.2022.116748 BindingDB Entry DOI: 10.7270/Q2MG7TGW |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50186278
(2-isopropyl-7-(3-(piperidin-1-yl)propoxy)-2,3,4,5-...)Show InChI InChI=1S/C21H34N2O/c1-18(2)23-14-6-8-19-16-21(10-9-20(19)17-23)24-15-7-13-22-11-4-3-5-12-22/h9-10,16,18H,3-8,11-15,17H2,1-2H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 0.200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description Displacement of [3H]N-alpha-methylhistamine from human cloned H3 receptor |
Bioorg Med Chem Lett 16: 3415-8 (2006)
Article DOI: 10.1016/j.bmcl.2006.04.004 BindingDB Entry DOI: 10.7270/Q2WM1D07 |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50186270
(2-benzyl-7-(3-(piperidin-1-yl)propoxy)-2,3,4,5-tet...)Show InChI InChI=1S/C25H34N2O/c1-3-9-22(10-4-1)20-27-16-7-11-23-19-25(13-12-24(23)21-27)28-18-8-17-26-14-5-2-6-15-26/h1,3-4,9-10,12-13,19H,2,5-8,11,14-18,20-21H2 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 0.200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description Displacement of [3H]N-alpha-methylhistamine from human cloned H3 receptor |
Bioorg Med Chem Lett 16: 3415-8 (2006)
Article DOI: 10.1016/j.bmcl.2006.04.004 BindingDB Entry DOI: 10.7270/Q2WM1D07 |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50186290
(3-ethyl-7-(3-(piperidin-1-yl)propoxy)-2,3,4,5-tetr...)Show InChI InChI=1S/C20H32N2O/c1-2-21-14-9-18-7-8-20(17-19(18)10-15-21)23-16-6-13-22-11-4-3-5-12-22/h7-8,17H,2-6,9-16H2,1H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 0.260 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description Displacement of [3H]N-alpha-methylhistamine from human cloned H3 receptor |
Bioorg Med Chem Lett 16: 3415-8 (2006)
Article DOI: 10.1016/j.bmcl.2006.04.004 BindingDB Entry DOI: 10.7270/Q2WM1D07 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50405890
(CHEMBL4782535)Show InChI InChI=1S/C13H15NO5S2/c1-8(2)7-18-13(15)19-10-4-3-9-5-12(21(14,16)17)20-11(9)6-10/h3-6,8H,7H2,1-2H3,(H2,14,16,17) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| | 0.320 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Antihistaminic activity against Histamine H1 receptor was measured on isolated terminal part of guinea pig ileum |
Citation and Details
|
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50186269
(2-ethyl-7-(3-(piperidin-1-yl)propoxy)-1,2,3,4-tetr...)Show InChI InChI=1S/C19H30N2O/c1-2-20-13-9-17-7-8-19(15-18(17)16-20)22-14-6-12-21-10-4-3-5-11-21/h7-8,15H,2-6,9-14,16H2,1H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 0.340 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description Displacement of [3H]N-alpha-methylhistamine from human cloned H3 receptor |
Bioorg Med Chem Lett 16: 3415-8 (2006)
Article DOI: 10.1016/j.bmcl.2006.04.004 BindingDB Entry DOI: 10.7270/Q2WM1D07 |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50186309
(2-ethyl-7-(3-(piperidin-1-yl)propoxy)-2,3,4,5-tetr...)Show InChI InChI=1S/C20H32N2O/c1-2-21-13-6-8-18-16-20(10-9-19(18)17-21)23-15-7-14-22-11-4-3-5-12-22/h9-10,16H,2-8,11-15,17H2,1H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 0.340 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description Displacement of [3H]N-alpha-methylhistamine from human cloned H3 receptor |
Bioorg Med Chem Lett 16: 3415-8 (2006)
Article DOI: 10.1016/j.bmcl.2006.04.004 BindingDB Entry DOI: 10.7270/Q2WM1D07 |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50186292
(2-(cyclohexylmethyl)-7-(3-(piperidin-1-yl)propoxy)...)Show InChI InChI=1S/C24H38N2O/c1-3-8-21(9-4-1)19-26-16-12-22-10-11-24(18-23(22)20-26)27-17-7-15-25-13-5-2-6-14-25/h10-11,18,21H,1-9,12-17,19-20H2 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 0.350 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description Displacement of [3H]N-alpha-methylhistamine from human cloned H3 receptor |
Bioorg Med Chem Lett 16: 3415-8 (2006)
Article DOI: 10.1016/j.bmcl.2006.04.004 BindingDB Entry DOI: 10.7270/Q2WM1D07 |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50186292
(2-(cyclohexylmethyl)-7-(3-(piperidin-1-yl)propoxy)...)Show InChI InChI=1S/C24H38N2O/c1-3-8-21(9-4-1)19-26-16-12-22-10-11-24(18-23(22)20-26)27-17-7-15-25-13-5-2-6-14-25/h10-11,18,21H,1-9,12-17,19-20H2 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 0.460 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description Displacement of [3H]N-alpha-methylhistamine from rat cloned H3 receptor |
Bioorg Med Chem Lett 16: 3415-8 (2006)
Article DOI: 10.1016/j.bmcl.2006.04.004 BindingDB Entry DOI: 10.7270/Q2WM1D07 |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50186316
(2-(phenylsulfonyl)-7-(3-(piperidin-1-yl)propoxy)-1...)Show SMILES O=S(=O)(N1CCc2ccc(OCCCN3CCCCC3)cc2C1)c1ccccc1 Show InChI InChI=1S/C23H30N2O3S/c26-29(27,23-8-3-1-4-9-23)25-16-12-20-10-11-22(18-21(20)19-25)28-17-7-15-24-13-5-2-6-14-24/h1,3-4,8-11,18H,2,5-7,12-17,19H2 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 0.530 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description Displacement of [3H]N-alpha-methylhistamine from human cloned H3 receptor |
Bioorg Med Chem Lett 16: 3415-8 (2006)
Article DOI: 10.1016/j.bmcl.2006.04.004 BindingDB Entry DOI: 10.7270/Q2WM1D07 |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50186306
(3-(cyclohexylmethyl)-7-(3-(piperidin-1-yl)propoxy)...)Show InChI InChI=1S/C25H40N2O/c1-3-8-22(9-4-1)21-27-17-12-23-10-11-25(20-24(23)13-18-27)28-19-7-16-26-14-5-2-6-15-26/h10-11,20,22H,1-9,12-19,21H2 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 0.530 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description Displacement of [3H]N-alpha-methylhistamine from human cloned H3 receptor |
Bioorg Med Chem Lett 16: 3415-8 (2006)
Article DOI: 10.1016/j.bmcl.2006.04.004 BindingDB Entry DOI: 10.7270/Q2WM1D07 |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50186283
(2-ethyl-6-(3-(piperidin-1-yl)propoxy)-1,2,3,4-tetr...)Show InChI InChI=1S/C19H30N2O/c1-2-20-13-9-17-15-19(8-7-18(17)16-20)22-14-6-12-21-10-4-3-5-11-21/h7-8,15H,2-6,9-14,16H2,1H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 0.540 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description Displacement of [3H]N-alpha-methylhistamine from human cloned H3 receptor |
Bioorg Med Chem Lett 16: 3415-8 (2006)
Article DOI: 10.1016/j.bmcl.2006.04.004 BindingDB Entry DOI: 10.7270/Q2WM1D07 |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50186309
(2-ethyl-7-(3-(piperidin-1-yl)propoxy)-2,3,4,5-tetr...)Show InChI InChI=1S/C20H32N2O/c1-2-21-13-6-8-18-16-20(10-9-19(18)17-21)23-15-7-14-22-11-4-3-5-12-22/h9-10,16H,2-8,11-15,17H2,1H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 0.560 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description Displacement of [3H]N-alpha-methylhistamine from rat cloned H3 receptor |
Bioorg Med Chem Lett 16: 3415-8 (2006)
Article DOI: 10.1016/j.bmcl.2006.04.004 BindingDB Entry DOI: 10.7270/Q2WM1D07 |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50186293
(7-(3-(piperidin-1-yl)propoxy)-1,2,3,4-tetrahydrois...)Show InChI InChI=1S/C17H26N2O/c1-2-9-19(10-3-1)11-4-12-20-17-6-5-15-7-8-18-14-16(15)13-17/h5-6,13,18H,1-4,7-12,14H2 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 0.600 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description Displacement of [3H]N-alpha-methylhistamine from human cloned H3 receptor |
Bioorg Med Chem Lett 16: 3415-8 (2006)
Article DOI: 10.1016/j.bmcl.2006.04.004 BindingDB Entry DOI: 10.7270/Q2WM1D07 |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50186269
(2-ethyl-7-(3-(piperidin-1-yl)propoxy)-1,2,3,4-tetr...)Show InChI InChI=1S/C19H30N2O/c1-2-20-13-9-17-7-8-19(15-18(17)16-20)22-14-6-12-21-10-4-3-5-11-21/h7-8,15H,2-6,9-14,16H2,1H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 0.640 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description Displacement of [3H]N-alpha-methylhistamine from rat cloned H3 receptor |
Bioorg Med Chem Lett 16: 3415-8 (2006)
Article DOI: 10.1016/j.bmcl.2006.04.004 BindingDB Entry DOI: 10.7270/Q2WM1D07 |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50186311
(3-isopropyl-7-(3-(piperidin-1-yl)propoxy)-2,3,4,5-...)Show InChI InChI=1S/C21H34N2O/c1-18(2)23-14-9-19-7-8-21(17-20(19)10-15-23)24-16-6-13-22-11-4-3-5-12-22/h7-8,17-18H,3-6,9-16H2,1-2H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 0.720 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description Displacement of [3H]N-alpha-methylhistamine from human cloned H3 receptor |
Bioorg Med Chem Lett 16: 3415-8 (2006)
Article DOI: 10.1016/j.bmcl.2006.04.004 BindingDB Entry DOI: 10.7270/Q2WM1D07 |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50186270
(2-benzyl-7-(3-(piperidin-1-yl)propoxy)-2,3,4,5-tet...)Show InChI InChI=1S/C25H34N2O/c1-3-9-22(10-4-1)20-27-16-7-11-23-19-25(13-12-24(23)21-27)28-18-8-17-26-14-5-2-6-15-26/h1,3-4,9-10,12-13,19H,2,5-8,11,14-18,20-21H2 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 0.800 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description Displacement of [3H]N-alpha-methylhistamine from rat cloned H3 receptor |
Bioorg Med Chem Lett 16: 3415-8 (2006)
Article DOI: 10.1016/j.bmcl.2006.04.004 BindingDB Entry DOI: 10.7270/Q2WM1D07 |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50186291
(2-isopropyl-7-(3-(piperidin-1-yl)propoxy)-1,2,3,4-...)Show InChI InChI=1S/C20H32N2O/c1-17(2)22-13-9-18-7-8-20(15-19(18)16-22)23-14-6-12-21-10-4-3-5-11-21/h7-8,15,17H,3-6,9-14,16H2,1-2H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 0.890 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description Displacement of [3H]N-alpha-methylhistamine from rat cloned H3 receptor |
Bioorg Med Chem Lett 16: 3415-8 (2006)
Article DOI: 10.1016/j.bmcl.2006.04.004 BindingDB Entry DOI: 10.7270/Q2WM1D07 |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50186306
(3-(cyclohexylmethyl)-7-(3-(piperidin-1-yl)propoxy)...)Show InChI InChI=1S/C25H40N2O/c1-3-8-22(9-4-1)21-27-17-12-23-10-11-25(20-24(23)13-18-27)28-19-7-16-26-14-5-2-6-15-26/h10-11,20,22H,1-9,12-19,21H2 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 0.970 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description Displacement of [3H]N-alpha-methylhistamine from rat cloned H3 receptor |
Bioorg Med Chem Lett 16: 3415-8 (2006)
Article DOI: 10.1016/j.bmcl.2006.04.004 BindingDB Entry DOI: 10.7270/Q2WM1D07 |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50186296
(2-(cyclohexylmethyl)-6-(3-(piperidin-1-yl)propoxy)...)Show InChI InChI=1S/C24H38N2O/c1-3-8-21(9-4-1)19-26-16-12-22-18-24(11-10-23(22)20-26)27-17-7-15-25-13-5-2-6-14-25/h10-11,18,21H,1-9,12-17,19-20H2 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 1.01 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description Displacement of [3H]N-alpha-methylhistamine from human cloned H3 receptor |
Bioorg Med Chem Lett 16: 3415-8 (2006)
Article DOI: 10.1016/j.bmcl.2006.04.004 BindingDB Entry DOI: 10.7270/Q2WM1D07 |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50186290
(3-ethyl-7-(3-(piperidin-1-yl)propoxy)-2,3,4,5-tetr...)Show InChI InChI=1S/C20H32N2O/c1-2-21-14-9-18-7-8-20(17-19(18)10-15-21)23-16-6-13-22-11-4-3-5-12-22/h7-8,17H,2-6,9-16H2,1H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 1.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description Displacement of [3H]N-alpha-methylhistamine from rat cloned H3 receptor |
Bioorg Med Chem Lett 16: 3415-8 (2006)
Article DOI: 10.1016/j.bmcl.2006.04.004 BindingDB Entry DOI: 10.7270/Q2WM1D07 |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50186278
(2-isopropyl-7-(3-(piperidin-1-yl)propoxy)-2,3,4,5-...)Show InChI InChI=1S/C21H34N2O/c1-18(2)23-14-6-8-19-16-21(10-9-20(19)17-23)24-15-7-13-22-11-4-3-5-12-22/h9-10,16,18H,3-8,11-15,17H2,1-2H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 1.29 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description Displacement of [3H]N-alpha-methylhistamine from rat cloned H3 receptor |
Bioorg Med Chem Lett 16: 3415-8 (2006)
Article DOI: 10.1016/j.bmcl.2006.04.004 BindingDB Entry DOI: 10.7270/Q2WM1D07 |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50186311
(3-isopropyl-7-(3-(piperidin-1-yl)propoxy)-2,3,4,5-...)Show InChI InChI=1S/C21H34N2O/c1-18(2)23-14-9-19-7-8-21(17-20(19)10-15-23)24-16-6-13-22-11-4-3-5-12-22/h7-8,17-18H,3-6,9-16H2,1-2H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 1.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description Displacement of [3H]N-alpha-methylhistamine from rat cloned H3 receptor |
Bioorg Med Chem Lett 16: 3415-8 (2006)
Article DOI: 10.1016/j.bmcl.2006.04.004 BindingDB Entry DOI: 10.7270/Q2WM1D07 |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50186281
((6-(3-(piperidin-1-yl)propoxy)-3,4-dihydroisoquino...)Show InChI InChI=1S/C22H28N2O2S/c25-22(21-6-4-15-27-21)24-13-9-18-16-20(8-7-19(18)17-24)26-14-5-12-23-10-2-1-3-11-23/h4,6-8,15-16H,1-3,5,9-14,17H2 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 2.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description Displacement of [3H]N-alpha-methylhistamine from human cloned H3 receptor |
Bioorg Med Chem Lett 16: 3415-8 (2006)
Article DOI: 10.1016/j.bmcl.2006.04.004 BindingDB Entry DOI: 10.7270/Q2WM1D07 |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50186295
(2-(methylsulfonyl)-7-(3-(piperidin-1-yl)propoxy)-2...)Show InChI InChI=1S/C19H30N2O3S/c1-25(22,23)21-13-5-7-17-15-19(9-8-18(17)16-21)24-14-6-12-20-10-3-2-4-11-20/h8-9,15H,2-7,10-14,16H2,1H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
| Article PubMed
| 2.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description Displacement of [3H]N-alpha-methylhistamine from human cloned H3 receptor |
Bioorg Med Chem Lett 16: 3415-8 (2006)
Article DOI: 10.1016/j.bmcl.2006.04.004 BindingDB Entry DOI: 10.7270/Q2WM1D07 |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50186285
(CHEMBL208829 | N-isopropyl-7-(3-(piperidin-1-yl)pr...)Show InChI InChI=1S/C21H33N3O2/c1-17(2)22-21(25)24-13-9-18-7-8-20(15-19(18)16-24)26-14-6-12-23-10-4-3-5-11-23/h7-8,15,17H,3-6,9-14,16H2,1-2H3,(H,22,25) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 4.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description Displacement of [3H]N-alpha-methylhistamine from human cloned H3 receptor |
Bioorg Med Chem Lett 16: 3415-8 (2006)
Article DOI: 10.1016/j.bmcl.2006.04.004 BindingDB Entry DOI: 10.7270/Q2WM1D07 |
More data for this Ligand-Target Pair | |
Prolyl endopeptidase FAP
(Homo sapiens (Human)) | BDBM50050513
((R)-1-((S)-2-amino-3-methylbutanoyl)pyrrolidin-2-y...)Show InChI InChI=1S/C9H19BN2O3/c1-6(2)8(11)9(13)12-5-3-4-7(12)10(14)15/h6-8,14-15H,3-5,11H2,1-2H3/t7-,8-/m0/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| |
Citation and Details
Article DOI: 10.1016/j.bmc.2022.116748 BindingDB Entry DOI: 10.7270/Q2MG7TGW |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50186286
(1-(phenylsulfonyl)-7-(3-(piperidin-1-yl)propoxy)-1...)Show SMILES O=S(=O)(N1CCCc2ccc(OCCCN3CCCCC3)cc12)c1ccccc1 Show InChI InChI=1S/C23H30N2O3S/c26-29(27,22-10-3-1-4-11-22)25-17-7-9-20-12-13-21(19-23(20)25)28-18-8-16-24-14-5-2-6-15-24/h1,3-4,10-13,19H,2,5-9,14-18H2 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 7.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description Displacement of [3H]N-alpha-methylhistamine from human cloned H3 receptor |
Bioorg Med Chem Lett 16: 3415-8 (2006)
Article DOI: 10.1016/j.bmcl.2006.04.004 BindingDB Entry DOI: 10.7270/Q2WM1D07 |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50186305
(2-(phenylsulfonyl)-6-(3-(piperidin-1-yl)propoxy)-1...)Show SMILES O=S(=O)(N1CCc2cc(OCCCN3CCCCC3)ccc2C1)c1ccccc1 Show InChI InChI=1S/C23H30N2O3S/c26-29(27,23-8-3-1-4-9-23)25-16-12-20-18-22(11-10-21(20)19-25)28-17-7-15-24-13-5-2-6-14-24/h1,3-4,8-11,18H,2,5-7,12-17,19H2 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 7.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description Displacement of [3H]N-alpha-methylhistamine from human cloned H3 receptor |
Bioorg Med Chem Lett 16: 3415-8 (2006)
Article DOI: 10.1016/j.bmcl.2006.04.004 BindingDB Entry DOI: 10.7270/Q2WM1D07 |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50186273
((7-(3-(piperidin-1-yl)propoxy)-3,4-dihydroisoquino...)Show InChI InChI=1S/C22H28N2O2S/c25-22(21-6-4-15-27-21)24-13-9-18-7-8-20(16-19(18)17-24)26-14-5-12-23-10-2-1-3-11-23/h4,6-8,15-16H,1-3,5,9-14,17H2 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 8.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description Displacement of [3H]N-alpha-methylhistamine from human cloned H3 receptor |
Bioorg Med Chem Lett 16: 3415-8 (2006)
Article DOI: 10.1016/j.bmcl.2006.04.004 BindingDB Entry DOI: 10.7270/Q2WM1D07 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50405889
(CHEMBL4741159)Show InChI InChI=1S/C10H10N2O3S2/c1-6(13)12-8-3-2-7-4-10(17(11,14)15)16-9(7)5-8/h2-5H,1H3,(H,12,13)(H2,11,14,15) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid PDB UniChem
| | 8.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Antihistaminic activity against Histamine H1 receptor was measured on isolated terminal part of guinea pig ileum |
Citation and Details
|
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50186300
(1-(7-(3-(piperidin-1-yl)propoxy)-1,2,4,5-tetrahydr...)Show InChI InChI=1S/C20H30N2O2/c1-17(23)22-13-8-18-6-7-20(16-19(18)9-14-22)24-15-5-12-21-10-3-2-4-11-21/h6-7,16H,2-5,8-15H2,1H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 11.6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description Displacement of [3H]N-alpha-methylhistamine from human cloned H3 receptor |
Bioorg Med Chem Lett 16: 3415-8 (2006)
Article DOI: 10.1016/j.bmcl.2006.04.004 BindingDB Entry DOI: 10.7270/Q2WM1D07 |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50186275
(3-(methylsulfonyl)-7-(3-(piperidin-1-yl)propoxy)-2...)Show InChI InChI=1S/C19H30N2O3S/c1-25(22,23)21-13-8-17-6-7-19(16-18(17)9-14-21)24-15-5-12-20-10-3-2-4-11-20/h6-7,16H,2-5,8-15H2,1H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
| Article PubMed
| 12.1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description Displacement of [3H]N-alpha-methylhistamine from human cloned H3 receptor |
Bioorg Med Chem Lett 16: 3415-8 (2006)
Article DOI: 10.1016/j.bmcl.2006.04.004 BindingDB Entry DOI: 10.7270/Q2WM1D07 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM10880
(AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...)Show InChI InChI=1S/C4H6N4O3S2/c1-2(9)6-3-7-8-4(12-3)13(5,10)11/h1H3,(H2,5,10,11)(H,6,7,9) | PDB MMDB
Reactome pathway KEGG
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B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
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| DrugBank MMDB PDB
| 13 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Antihistaminic activity against Histamine H1 receptor was measured on isolated terminal part of guinea pig ileum |
Citation and Details
|
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50186284
(2-(cyclohexylmethyl)-5-(3-(piperidin-1-yl)propoxy)...)Show InChI InChI=1S/C24H38N2O/c1-3-9-21(10-4-1)19-26-17-13-23-22(20-26)11-7-12-24(23)27-18-8-16-25-14-5-2-6-15-25/h7,11-12,21H,1-6,8-10,13-20H2 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 15.4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description Displacement of [3H]N-alpha-methylhistamine from human cloned H3 receptor |
Bioorg Med Chem Lett 16: 3415-8 (2006)
Article DOI: 10.1016/j.bmcl.2006.04.004 BindingDB Entry DOI: 10.7270/Q2WM1D07 |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50186297
(CHEMBL209099 | N-isopropyl-7-(3-(piperidin-1-yl)pr...)Show InChI InChI=1S/C22H35N3O2/c1-18(2)23-22(26)25-14-6-8-19-16-21(10-9-20(19)17-25)27-15-7-13-24-11-4-3-5-12-24/h9-10,16,18H,3-8,11-15,17H2,1-2H3,(H,23,26) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
| Article PubMed
| 17.1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description Displacement of [3H]N-alpha-methylhistamine from human cloned H3 receptor |
Bioorg Med Chem Lett 16: 3415-8 (2006)
Article DOI: 10.1016/j.bmcl.2006.04.004 BindingDB Entry DOI: 10.7270/Q2WM1D07 |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50186289
(1-(phenylsulfonyl)-6-(3-(piperidin-1-yl)propoxy)-1...)Show SMILES O=S(=O)(N1CCCc2cc(OCCCN3CCCCC3)ccc12)c1ccccc1 Show InChI InChI=1S/C23H30N2O3S/c26-29(27,22-10-3-1-4-11-22)25-17-7-9-20-19-21(12-13-23(20)25)28-18-8-16-24-14-5-2-6-15-24/h1,3-4,10-13,19H,2,5-9,14-18H2 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 18 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description Displacement of [3H]N-alpha-methylhistamine from human cloned H3 receptor |
Bioorg Med Chem Lett 16: 3415-8 (2006)
Article DOI: 10.1016/j.bmcl.2006.04.004 BindingDB Entry DOI: 10.7270/Q2WM1D07 |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50186277
(1-(7-(3-(piperidin-1-yl)propoxy)-3,4-dihydroisoqui...)Show InChI InChI=1S/C19H28N2O2/c1-16(22)21-12-8-17-6-7-19(14-18(17)15-21)23-13-5-11-20-9-3-2-4-10-20/h6-7,14H,2-5,8-13,15H2,1H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 19.4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description Displacement of [3H]N-alpha-methylhistamine from human cloned H3 receptor |
Bioorg Med Chem Lett 16: 3415-8 (2006)
Article DOI: 10.1016/j.bmcl.2006.04.004 BindingDB Entry DOI: 10.7270/Q2WM1D07 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50547697
(CHEMBL4739913) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid PDB UniChem
| | 20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Antihistaminic activity against Histamine H1 receptor was measured on isolated terminal part of guinea pig ileum |
Citation and Details
|
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50186279
((7-(3-(piperidin-1-yl)propoxy)-3,4-dihydroquinolin...)Show InChI InChI=1S/C22H28N2O2S/c25-22(21-8-5-16-27-21)24-14-4-7-18-9-10-19(17-20(18)24)26-15-6-13-23-11-2-1-3-12-23/h5,8-10,16-17H,1-4,6-7,11-15H2 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 22.6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description Displacement of [3H]N-alpha-methylhistamine from human cloned H3 receptor |
Bioorg Med Chem Lett 16: 3415-8 (2006)
Article DOI: 10.1016/j.bmcl.2006.04.004 BindingDB Entry DOI: 10.7270/Q2WM1D07 |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50186288
(2-(methylsulfonyl)-7-(3-(piperidin-1-yl)propoxy)-1...)Show InChI InChI=1S/C18H28N2O3S/c1-24(21,22)20-12-8-16-6-7-18(14-17(16)15-20)23-13-5-11-19-9-3-2-4-10-19/h6-7,14H,2-5,8-13,15H2,1H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 23.8 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description Displacement of [3H]N-alpha-methylhistamine from human cloned H3 receptor |
Bioorg Med Chem Lett 16: 3415-8 (2006)
Article DOI: 10.1016/j.bmcl.2006.04.004 BindingDB Entry DOI: 10.7270/Q2WM1D07 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50405887
(CHEMBL4750765)Show InChI InChI=1S/C9H9NO3S2/c1-13-7-2-3-8-6(4-7)5-9(14-8)15(10,11)12/h2-5H,1H3,(H2,10,11,12) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid PDB UniChem
Similars
| | 25 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Antihistaminic activity against Histamine H1 receptor was measured on isolated terminal part of guinea pig ileum |
Citation and Details
|
More data for this Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM16669
(CHEMBL281376 | N-(5-sulfamoyl-1,3,4-thiadiazol-2-y...)Show InChI InChI=1S/C9H8N4O3S2/c10-18(15,16)9-13-12-8(17-9)11-7(14)6-4-2-1-3-5-6/h1-5H,(H2,10,15,16)(H,11,12,14) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Patents
Similars
| | 29 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Antihistaminic activity against Histamine H1 receptor was measured on isolated terminal part of guinea pig ileum |
Citation and Details
|
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50186268
(1-(cyclohexylmethyl)-6-(3-(piperidin-1-yl)propoxy)...)Show InChI InChI=1S/C24H38N2O/c1-3-9-21(10-4-1)20-26-17-7-11-22-19-23(12-13-24(22)26)27-18-8-16-25-14-5-2-6-15-25/h12-13,19,21H,1-11,14-18,20H2 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 31 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description Displacement of [3H]N-alpha-methylhistamine from human cloned H3 receptor |
Bioorg Med Chem Lett 16: 3415-8 (2006)
Article DOI: 10.1016/j.bmcl.2006.04.004 BindingDB Entry DOI: 10.7270/Q2WM1D07 |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50186297
(CHEMBL209099 | N-isopropyl-7-(3-(piperidin-1-yl)pr...)Show InChI InChI=1S/C22H35N3O2/c1-18(2)23-22(26)25-14-6-8-19-16-21(10-9-20(19)17-25)27-15-7-13-24-11-4-3-5-12-24/h9-10,16,18H,3-8,11-15,17H2,1-2H3,(H,23,26) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
| Article PubMed
| 32.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description Displacement of [3H]N-alpha-methylhistamine from rat cloned H3 receptor |
Bioorg Med Chem Lett 16: 3415-8 (2006)
Article DOI: 10.1016/j.bmcl.2006.04.004 BindingDB Entry DOI: 10.7270/Q2WM1D07 |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50186277
(1-(7-(3-(piperidin-1-yl)propoxy)-3,4-dihydroisoqui...)Show InChI InChI=1S/C19H28N2O2/c1-16(22)21-12-8-17-6-7-19(14-18(17)15-21)23-13-5-11-20-9-3-2-4-10-20/h6-7,14H,2-5,8-13,15H2,1H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 36.7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Lilly Research Laboratories
Curated by ChEMBL
| Assay Description Displacement of [3H]N-alpha-methylhistamine from rat cloned H3 receptor |
Bioorg Med Chem Lett 16: 3415-8 (2006)
Article DOI: 10.1016/j.bmcl.2006.04.004 BindingDB Entry DOI: 10.7270/Q2WM1D07 |
More data for this Ligand-Target Pair | |
Carbonic anhydrase 2
(Homo sapiens (Human)) | BDBM50405888
(CHEMBL5280695)Show InChI InChI=1S/C9H9NO3S2/c1-13-7-3-2-6-4-9(15(10,11)12)14-8(6)5-7/h2-5H,1H3,(H2,10,11,12) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| | 38 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Antihistaminic activity against Histamine H1 receptor was measured on isolated terminal part of guinea pig ileum |
Citation and Details
|
More data for this Ligand-Target Pair | |