Compile Data Set for Download or QSAR

Found 30 hits with Last Name = 'deng' and Initial = 'dy'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bone morphogenetic protein 4 (Homo sapiens (Human))	BDBM50262079 (4-(6-(4-(piperazin-1-yl)phenyl)pyrazolo[1,5-a]pyri...) Show SMILES C1CN(CCN1)c1ccc(cc1)-c1cnc2c(cnn2c1)-c1ccnc2ccccc12 Show InChI InChI=1S/C25H22N6/c1-2-4-24-22(3-1)21(9-10-27-24)23-16-29-31-17-19(15-28-25(23)31)18-5-7-20(8-6-18)30-13-11-26-12-14-30/h1-10,15-17,26H,11-14H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	4.90	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Inhibition of BMP4 (unknown origin)-induced phosphorylation of SMAD 1/5/8 by cytoblot cellular ELISA				Bioorg Med Chem Lett 18: 4388-92 (2008) Article DOI: 10.1016/j.bmcl.2008.06.052 BindingDB Entry DOI: 10.7270/Q2BR8S0V
					More data for this Ligand-Target Pair
Bone morphogenetic protein 4 (Homo sapiens (Human))	BDBM50262178 (4-(6-(4-(piperazin-1-yl)phenyl)H-pyrazolo[1,5-a]py...) Show SMILES C1CN(CCN1)c1ccc(cc1)-c1ccc2c(cnn2c1)-c1ccnc2ccccc12 Show InChI InChI=1S/C26H23N5/c1-2-4-25-23(3-1)22(11-12-28-25)24-17-29-31-18-20(7-10-26(24)31)19-5-8-21(9-6-19)30-15-13-27-14-16-30/h1-12,17-18,27H,13-16H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Inhibition of BMP4 (unknown origin)-induced phosphorylation of SMAD 1/5/8 by cytoblot cellular ELISA				Bioorg Med Chem Lett 18: 4388-92 (2008) Article DOI: 10.1016/j.bmcl.2008.06.052 BindingDB Entry DOI: 10.7270/Q2BR8S0V
					More data for this Ligand-Target Pair
Bone morphogenetic protein 4 (Homo sapiens (Human))	BDBM50262017 (4-(6-(4-(2-(4-methylpiperazin-1-yl)ethoxy)phenyl)p...) Show SMILES CN1CCN(CCOc2ccc(cc2)-c2cnc3c(cnn3c2)-c2ccnc3ccccc23)CC1 Show InChI InChI=1S/C28H28N6O/c1-32-12-14-33(15-13-32)16-17-35-23-8-6-21(7-9-23)22-18-30-28-26(19-31-34(28)20-22)24-10-11-29-27-5-3-2-4-25(24)27/h2-11,18-20H,12-17H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Inhibition of BMP4 (unknown origin)-induced phosphorylation of SMAD 1/5/8 by cytoblot cellular ELISA				Bioorg Med Chem Lett 18: 4388-92 (2008) Article DOI: 10.1016/j.bmcl.2008.06.052 BindingDB Entry DOI: 10.7270/Q2BR8S0V
					More data for this Ligand-Target Pair
Bone morphogenetic protein 4 (Homo sapiens (Human))	BDBM50262016 (4-(6-(4-methoxyphenyl)pyrazolo[1,5-a]pyrimidin-3-y...) Show SMILES COc1ccc(cc1)-c1cnc2c(cnn2c1)-c1ccnc2ccccc12 Show InChI InChI=1S/C22H16N4O/c1-27-17-8-6-15(7-9-17)16-12-24-22-20(13-25-26(22)14-16)18-10-11-23-21-5-3-2-4-19(18)21/h2-14H,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Inhibition of BMP4 (unknown origin)-induced phosphorylation of SMAD 1/5/8 by cytoblot cellular ELISA				Bioorg Med Chem Lett 18: 4388-92 (2008) Article DOI: 10.1016/j.bmcl.2008.06.052 BindingDB Entry DOI: 10.7270/Q2BR8S0V
					More data for this Ligand-Target Pair
Bone morphogenetic protein 4 (Homo sapiens (Human))	BDBM50262018 (4-(6-(4-(2-(piperidin-1-yl)ethoxy)phenyl)pyrazolo[...) Show SMILES C(CN1CCCCC1)Oc1ccc(cc1)-c1cnc2c(cnn2c1)-c1ccnc2ccccc12 Show InChI InChI=1S/C28H27N5O/c1-4-14-32(15-5-1)16-17-34-23-10-8-21(9-11-23)22-18-30-28-26(19-31-33(28)20-22)24-12-13-29-27-7-3-2-6-25(24)27/h2-3,6-13,18-20H,1,4-5,14-17H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Inhibition of BMP4 (unknown origin)-induced phosphorylation of SMAD 1/5/8 by cytoblot cellular ELISA				Bioorg Med Chem Lett 18: 4388-92 (2008) Article DOI: 10.1016/j.bmcl.2008.06.052 BindingDB Entry DOI: 10.7270/Q2BR8S0V
					More data for this Ligand-Target Pair
Bone morphogenetic protein 4 (Homo sapiens (Human))	BDBM50262177 (4-(6-(4-methoxyphenyl)H-pyrazolo[1,5-a]pyridin-3-y...) Show SMILES COc1ccc(cc1)-c1ccc2c(cnn2c1)-c1ccnc2ccccc12 Show InChI InChI=1S/C23H17N3O/c1-27-18-9-6-16(7-10-18)17-8-11-23-21(14-25-26(23)15-17)19-12-13-24-22-5-3-2-4-20(19)22/h2-15H,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Inhibition of BMP4 (unknown origin)-induced phosphorylation of SMAD 1/5/8 by cytoblot cellular ELISA				Bioorg Med Chem Lett 18: 4388-92 (2008) Article DOI: 10.1016/j.bmcl.2008.06.052 BindingDB Entry DOI: 10.7270/Q2BR8S0V
					More data for this Ligand-Target Pair
Bone morphogenetic protein 4 (Homo sapiens (Human))	BDBM50262078 (4-(3-(quinolin-4-yl)pyrazolo[1,5-a]pyrimidin-6-yl)...) Show SMILES Oc1ccc(cc1)-c1cnc2c(cnn2c1)-c1ccnc2ccccc12 Show InChI InChI=1S/C21H14N4O/c26-16-7-5-14(6-8-16)15-11-23-21-19(12-24-25(21)13-15)17-9-10-22-20-4-2-1-3-18(17)20/h1-13,26H	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Inhibition of BMP4 (unknown origin)-induced phosphorylation of SMAD 1/5/8 by cytoblot cellular ELISA				Bioorg Med Chem Lett 18: 4388-92 (2008) Article DOI: 10.1016/j.bmcl.2008.06.052 BindingDB Entry DOI: 10.7270/Q2BR8S0V
					More data for this Ligand-Target Pair
Bone morphogenetic protein 4 (Homo sapiens (Human))	BDBM50262127 (7-chloro-4-(6-(4-(piperazin-1-yl)phenyl)pyrazolo[1...) Show SMILES Clc1ccc2c(ccnc2c1)-c1cnn2cc(cnc12)-c1ccc(cc1)N1CCNCC1 Show InChI InChI=1S/C25H21ClN6/c26-19-3-6-22-21(7-8-28-24(22)13-19)23-15-30-32-16-18(14-29-25(23)32)17-1-4-20(5-2-17)31-11-9-27-10-12-31/h1-8,13-16,27H,9-12H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	350	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Inhibition of BMP4 (unknown origin)-induced phosphorylation of SMAD 1/5/8 by cytoblot cellular ELISA				Bioorg Med Chem Lett 18: 4388-92 (2008) Article DOI: 10.1016/j.bmcl.2008.06.052 BindingDB Entry DOI: 10.7270/Q2BR8S0V
					More data for this Ligand-Target Pair
Bone morphogenetic protein 4 (Homo sapiens (Human))	BDBM50262685 (6-(4-(2-(piperidin-1-yl)ethoxy)phenyl)-3-(pyridin-...) Show SMILES C(CN1CCCCC1)Oc1ccc(cc1)-c1cnc2c(cnn2c1)-c1ccncc1 Show InChI InChI=1S/C24H25N5O/c1-2-12-28(13-3-1)14-15-30-22-6-4-19(5-7-22)21-16-26-24-23(17-27-29(24)18-21)20-8-10-25-11-9-20/h4-11,16-18H,1-3,12-15H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	430	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Inhibition of BMP4 (unknown origin)-induced phosphorylation of SMAD 1/5/8 by cytoblot cellular ELISA				Bioorg Med Chem Lett 18: 4388-92 (2008) Article DOI: 10.1016/j.bmcl.2008.06.052 BindingDB Entry DOI: 10.7270/Q2BR8S0V
					More data for this Ligand-Target Pair
Bone morphogenetic protein 4 (Homo sapiens (Human))	BDBM50261871 (6-(4-(2-(4-methylpiperazin-1-yl)ethoxy)phenyl)-3-(...) Show SMILES CN1CCN(CCOc2ccc(cc2)-c2cnc3c(cnn3c2)-c2ccncc2)CC1 Show InChI InChI=1S/C24H26N6O/c1-28-10-12-29(13-11-28)14-15-31-22-4-2-19(3-5-22)21-16-26-24-23(17-27-30(24)18-21)20-6-8-25-9-7-20/h2-9,16-18H,10-15H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	450	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Inhibition of BMP4 (unknown origin)-induced phosphorylation of SMAD 1/5/8 by cytoblot cellular ELISA				Bioorg Med Chem Lett 18: 4388-92 (2008) Article DOI: 10.1016/j.bmcl.2008.06.052 BindingDB Entry DOI: 10.7270/Q2BR8S0V
					More data for this Ligand-Target Pair
Bone morphogenetic protein 4 (Homo sapiens (Human))	BDBM50261870 (CHEMBL511216 | N,N-diethyl-2-(4-(3-(pyridin-4-yl)p...) Show SMILES CCN(CC)CCOc1ccc(cc1)-c1cnc2c(cnn2c1)-c1ccncc1 Show InChI InChI=1S/C23H25N5O/c1-3-27(4-2)13-14-29-21-7-5-18(6-8-21)20-15-25-23-22(16-26-28(23)17-20)19-9-11-24-12-10-19/h5-12,15-17H,3-4,13-14H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Inhibition of BMP4 (unknown origin)-induced phosphorylation of SMAD 1/5/8 by cytoblot cellular ELISA				Bioorg Med Chem Lett 18: 4388-92 (2008) Article DOI: 10.1016/j.bmcl.2008.06.052 BindingDB Entry DOI: 10.7270/Q2BR8S0V
					More data for this Ligand-Target Pair
Bone morphogenetic protein 4 (Homo sapiens (Human))	BDBM50262081 (7-chloro-4-(6-(4-methoxyphenyl)pyrazolo[1,5-a]pyri...) Show SMILES COc1ccc(cc1)-c1cnc2c(cnn2c1)-c1ccnc2cc(Cl)ccc12 Show InChI InChI=1S/C22H15ClN4O/c1-28-17-5-2-14(3-6-17)15-11-25-22-20(12-26-27(22)13-15)18-8-9-24-21-10-16(23)4-7-19(18)21/h2-13H,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Inhibition of BMP4 (unknown origin)-induced phosphorylation of SMAD 1/5/8 by cytoblot cellular ELISA				Bioorg Med Chem Lett 18: 4388-92 (2008) Article DOI: 10.1016/j.bmcl.2008.06.052 BindingDB Entry DOI: 10.7270/Q2BR8S0V
					More data for this Ligand-Target Pair
Bone morphogenetic protein 4 (Homo sapiens (Human))	BDBM50262020 (4-(6-phenylpyrazolo[1,5-a]pyrimidin-3-yl)quinoline...) Show SMILES c1nn2cc(cnc2c1-c1ccnc2ccccc12)-c1ccccc1 Show InChI InChI=1S/C21H14N4/c1-2-6-15(7-3-1)16-12-23-21-19(13-24-25(21)14-16)17-10-11-22-20-9-5-4-8-18(17)20/h1-14H	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	750	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Inhibition of BMP4 (unknown origin)-induced phosphorylation of SMAD 1/5/8 by cytoblot cellular ELISA				Bioorg Med Chem Lett 18: 4388-92 (2008) Article DOI: 10.1016/j.bmcl.2008.06.052 BindingDB Entry DOI: 10.7270/Q2BR8S0V
					More data for this Ligand-Target Pair
Bone morphogenetic protein 4 (Homo sapiens (Human))	BDBM5416 (4-(2-{4-[3-(pyridin-4-yl)pyrazolo[1,5-a]pyrimidin-...) Show SMILES C(CN1CCOCC1)Oc1ccc(cc1)-c1cnc2c(cnn2c1)-c1ccncc1 Show InChI InChI=1S/C23H23N5O2/c1-3-21(30-14-11-27-9-12-29-13-10-27)4-2-18(1)20-15-25-23-22(16-26-28(23)17-20)19-5-7-24-8-6-19/h1-8,15-17H,9-14H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Inhibition of BMP4 (unknown origin)-induced phosphorylation of SMAD 1/5/8 by cytoblot cellular ELISA				Bioorg Med Chem Lett 18: 4388-92 (2008) Article DOI: 10.1016/j.bmcl.2008.06.052 BindingDB Entry DOI: 10.7270/Q2BR8S0V
					More data for this Ligand-Target Pair
Bone morphogenetic protein 4 (Homo sapiens (Human))	BDBM50262130 (4-(3-(4-(2-(piperidin-1-yl)ethoxy)phenyl)H-pyrrolo...) Show SMILES C(CN1CCCCC1)Oc1ccc(cc1)-c1cnc2c(ccn2c1)-c1ccnc2ccccc12 Show InChI InChI=1S/C29H28N4O/c1-4-15-32(16-5-1)18-19-34-24-10-8-22(9-11-24)23-20-31-29-27(13-17-33(29)21-23)25-12-14-30-28-7-3-2-6-26(25)28/h2-3,6-14,17,20-21H,1,4-5,15-16,18-19H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Inhibition of BMP4 (unknown origin)-induced phosphorylation of SMAD 1/5/8 by cytoblot cellular ELISA				Bioorg Med Chem Lett 18: 4388-92 (2008) Article DOI: 10.1016/j.bmcl.2008.06.052 BindingDB Entry DOI: 10.7270/Q2BR8S0V
					More data for this Ligand-Target Pair
Bone morphogenetic protein 4 (Homo sapiens (Human))	BDBM50261979 (5-(6-(4-methoxyphenyl)pyrazolo[1,5-a]pyrimidin-3-y...) Show SMILES COc1ccc(cc1)-c1cnc2c(cnn2c1)-c1cccc2ncccc12 Show InChI InChI=1S/C22H16N4O/c1-27-17-9-7-15(8-10-17)16-12-24-22-20(13-25-26(22)14-16)18-4-2-6-21-19(18)5-3-11-23-21/h2-14H,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Inhibition of BMP4 (unknown origin)-induced phosphorylation of SMAD 1/5/8 by cytoblot cellular ELISA				Bioorg Med Chem Lett 18: 4388-92 (2008) Article DOI: 10.1016/j.bmcl.2008.06.052 BindingDB Entry DOI: 10.7270/Q2BR8S0V
					More data for this Ligand-Target Pair
Bone morphogenetic protein 4 (Homo sapiens (Human))	BDBM50261976 (3-(3-fluoropyridin-4-yl)-6-(4-(2-(4-methylpiperazi...) Show SMILES CN1CCN(CCOc2ccc(cc2)-c2cnc3c(cnn3c2)-c2ccncc2F)CC1 Show InChI InChI=1S/C24H25FN6O/c1-29-8-10-30(11-9-29)12-13-32-20-4-2-18(3-5-20)19-14-27-24-22(15-28-31(24)17-19)21-6-7-26-16-23(21)25/h2-7,14-17H,8-13H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Inhibition of BMP4 (unknown origin)-induced phosphorylation of SMAD 1/5/8 by cytoblot cellular ELISA				Bioorg Med Chem Lett 18: 4388-92 (2008) Article DOI: 10.1016/j.bmcl.2008.06.052 BindingDB Entry DOI: 10.7270/Q2BR8S0V
					More data for this Ligand-Target Pair
Bone morphogenetic protein 4 (Homo sapiens (Human))	BDBM50261872 (6-(3-(2-(4-methylpiperazin-1-yl)ethoxy)phenyl)-3-(...) Show SMILES CN1CCN(CCOc2cccc(c2)-c2cnc3c(cnn3c2)-c2ccncc2)CC1 Show InChI InChI=1S/C24H26N6O/c1-28-9-11-29(12-10-28)13-14-31-22-4-2-3-20(15-22)21-16-26-24-23(17-27-30(24)18-21)19-5-7-25-8-6-19/h2-8,15-18H,9-14H2,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Inhibition of BMP4 (unknown origin)-induced phosphorylation of SMAD 1/5/8 by cytoblot cellular ELISA				Bioorg Med Chem Lett 18: 4388-92 (2008) Article DOI: 10.1016/j.bmcl.2008.06.052 BindingDB Entry DOI: 10.7270/Q2BR8S0V
					More data for this Ligand-Target Pair
Bone morphogenetic protein 4 (Homo sapiens (Human))	BDBM50262019 (4-(pyrazolo[1,5-a]pyrimidin-3-yl)quinoline | CHEMB...) Show SMILES c1nn2cccnc2c1-c1ccnc2ccccc12 Show InChI InChI=1S/C15H10N4/c1-2-5-14-12(4-1)11(6-8-16-14)13-10-18-19-9-3-7-17-15(13)19/h1-10H	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Inhibition of BMP4 (unknown origin)-induced phosphorylation of SMAD 1/5/8 by cytoblot cellular ELISA				Bioorg Med Chem Lett 18: 4388-92 (2008) Article DOI: 10.1016/j.bmcl.2008.06.052 BindingDB Entry DOI: 10.7270/Q2BR8S0V
					More data for this Ligand-Target Pair
Bone morphogenetic protein 4 (Homo sapiens (Human))	BDBM5420 (4-[6-(4-methoxyphenyl)pyrazolo[1,5-a]pyrimidin-3-y...) Show SMILES COc1ccc(cc1)-c1cnc2c(cnn2c1)-c1ccncc1 Show InChI InChI=1S/C18H14N4O/c1-23-16-4-2-13(3-5-16)15-10-20-18-17(11-21-22(18)12-15)14-6-8-19-9-7-14/h2-12H,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Inhibition of BMP4 (unknown origin)-induced phosphorylation of SMAD 1/5/8 by cytoblot cellular ELISA				Bioorg Med Chem Lett 18: 4388-92 (2008) Article DOI: 10.1016/j.bmcl.2008.06.052 BindingDB Entry DOI: 10.7270/Q2BR8S0V
					More data for this Ligand-Target Pair
Bone morphogenetic protein 4 (Homo sapiens (Human))	BDBM5415 (3-(6-{4-[2-(piperidin-1-yl)ethoxy]phenyl}pyrazolo[...) Show SMILES C(CN1CCCCC1)Oc1ccc(cc1)-c1cnc2c(cnn2c1)-c1cccnc1 Show InChI InChI=1S/C24H25N5O/c1-2-11-28(12-3-1)13-14-30-22-8-6-19(7-9-22)21-16-26-24-23(17-27-29(24)18-21)20-5-4-10-25-15-20/h4-10,15-18H,1-3,11-14H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Inhibition of BMP4 (unknown origin)-induced phosphorylation of SMAD 1/5/8 by cytoblot cellular ELISA				Bioorg Med Chem Lett 18: 4388-92 (2008) Article DOI: 10.1016/j.bmcl.2008.06.052 BindingDB Entry DOI: 10.7270/Q2BR8S0V
					More data for this Ligand-Target Pair
Bone morphogenetic protein 4 (Homo sapiens (Human))	BDBM50261927 (3-phenyl-6-(4-(2-(piperidin-1-yl)ethoxy)phenyl)pyr...) Show SMILES C(CN1CCCCC1)Oc1ccc(cc1)-c1cnc2c(cnn2c1)-c1ccccc1 Show InChI InChI=1S/C25H26N4O/c1-3-7-21(8-4-1)24-18-27-29-19-22(17-26-25(24)29)20-9-11-23(12-10-20)30-16-15-28-13-5-2-6-14-28/h1,3-4,7-12,17-19H,2,5-6,13-16H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Inhibition of BMP4 (unknown origin)-induced phosphorylation of SMAD 1/5/8 by cytoblot cellular ELISA				Bioorg Med Chem Lett 18: 4388-92 (2008) Article DOI: 10.1016/j.bmcl.2008.06.052 BindingDB Entry DOI: 10.7270/Q2BR8S0V
					More data for this Ligand-Target Pair
Bone morphogenetic protein 4 (Homo sapiens (Human))	BDBM50261977 (6-(6-(4-methoxyphenyl)pyrazolo[1,5-a]pyrimidin-3-y...) Show SMILES COc1ccc(cc1)-c1cnc2c(cnn2c1)-c1ccc2ncccc2c1 Show InChI InChI=1S/C22H16N4O/c1-27-19-7-4-15(5-8-19)18-12-24-22-20(13-25-26(22)14-18)16-6-9-21-17(11-16)3-2-10-23-21/h2-14H,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Inhibition of BMP4 (unknown origin)-induced phosphorylation of SMAD 1/5/8 by cytoblot cellular ELISA				Bioorg Med Chem Lett 18: 4388-92 (2008) Article DOI: 10.1016/j.bmcl.2008.06.052 BindingDB Entry DOI: 10.7270/Q2BR8S0V
					More data for this Ligand-Target Pair
Bone morphogenetic protein 4 (Homo sapiens (Human))	BDBM50261978 (8-(6-(4-methoxyphenyl)pyrazolo[1,5-a]pyrimidin-3-y...) Show SMILES COc1ccc(cc1)-c1cnc2c(cnn2c1)-c1cccc2cccnc12 Show InChI InChI=1S/C22H16N4O/c1-27-18-9-7-15(8-10-18)17-12-24-22-20(13-25-26(22)14-17)19-6-2-4-16-5-3-11-23-21(16)19/h2-14H,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Inhibition of BMP4 (unknown origin)-induced phosphorylation of SMAD 1/5/8 by cytoblot cellular ELISA				Bioorg Med Chem Lett 18: 4388-92 (2008) Article DOI: 10.1016/j.bmcl.2008.06.052 BindingDB Entry DOI: 10.7270/Q2BR8S0V
					More data for this Ligand-Target Pair
Bone morphogenetic protein 4 (Homo sapiens (Human))	BDBM50261926 (6-(4-(2-(piperidin-1-yl)ethoxy)phenyl)pyrazolo[1,5...) Show SMILES C(CN1CCCCC1)Oc1ccc(cc1)-c1cnc2ccnn2c1 Show InChI InChI=1S/C19H22N4O/c1-2-10-22(11-3-1)12-13-24-18-6-4-16(5-7-18)17-14-20-19-8-9-21-23(19)15-17/h4-9,14-15H,1-3,10-13H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Inhibition of BMP4 (unknown origin)-induced phosphorylation of SMAD 1/5/8 by cytoblot cellular ELISA				Bioorg Med Chem Lett 18: 4388-92 (2008) Article DOI: 10.1016/j.bmcl.2008.06.052 BindingDB Entry DOI: 10.7270/Q2BR8S0V
					More data for this Ligand-Target Pair
Bone morphogenetic protein 4 (Homo sapiens (Human))	BDBM50262080 (4-(6-(3-(piperazin-1-yl)phenyl)pyrazolo[1,5-a]pyri...) Show SMILES C1CN(CCN1)c1cccc(c1)-c1cnc2c(cnn2c1)-c1ccnc2ccccc12 Show InChI InChI=1S/C25H22N6/c1-2-7-24-22(6-1)21(8-9-27-24)23-16-29-31-17-19(15-28-25(23)31)18-4-3-5-20(14-18)30-12-10-26-11-13-30/h1-9,14-17,26H,10-13H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Inhibition of BMP4 (unknown origin)-induced phosphorylation of SMAD 1/5/8 by cytoblot cellular ELISA				Bioorg Med Chem Lett 18: 4388-92 (2008) Article DOI: 10.1016/j.bmcl.2008.06.052 BindingDB Entry DOI: 10.7270/Q2BR8S0V
					More data for this Ligand-Target Pair
Bone morphogenetic protein 4 (Homo sapiens (Human))	BDBM50262128 (CHEMBL469259 | methyl 3-(4-methoxyphenyl)-8-(quino...) Show SMILES COC(=O)c1cc(-c2ccnc3ccccc23)c2ncc(cn12)-c1ccc(OC)cc1 Show InChI InChI=1S/C25H19N3O3/c1-30-18-9-7-16(8-10-18)17-14-27-24-21(13-23(25(29)31-2)28(24)15-17)19-11-12-26-22-6-4-3-5-20(19)22/h3-15H,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Inhibition of BMP4 (unknown origin)-induced phosphorylation of SMAD 1/5/8 by cytoblot cellular ELISA				Bioorg Med Chem Lett 18: 4388-92 (2008) Article DOI: 10.1016/j.bmcl.2008.06.052 BindingDB Entry DOI: 10.7270/Q2BR8S0V
					More data for this Ligand-Target Pair
Bone morphogenetic protein 4 (Homo sapiens (Human))	BDBM50262129 (4-(3-(4-methoxyphenyl)H-pyrrolo[1,2-a]pyrimidin-8-...) Show SMILES COc1ccc(cc1)-c1cnc2c(ccn2c1)-c1ccnc2ccccc12 Show InChI InChI=1S/C23H17N3O/c1-27-18-8-6-16(7-9-18)17-14-25-23-21(11-13-26(23)15-17)19-10-12-24-22-5-3-2-4-20(19)22/h2-15H,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Inhibition of BMP4 (unknown origin)-induced phosphorylation of SMAD 1/5/8 by cytoblot cellular ELISA				Bioorg Med Chem Lett 18: 4388-92 (2008) Article DOI: 10.1016/j.bmcl.2008.06.052 BindingDB Entry DOI: 10.7270/Q2BR8S0V
					More data for this Ligand-Target Pair
Bone morphogenetic protein 4 (Homo sapiens (Human))	BDBM50261925 (2-methyl-6-(4-(2-(4-methylpiperazin-1-yl)ethoxy)ph...) Show SMILES CN1CCN(CCOc2ccc(cc2)-c2cnc3c(c(C)nn3c2)-c2ccncc2)CC1 Show InChI InChI=1S/C25H28N6O/c1-19-24(21-7-9-26-10-8-21)25-27-17-22(18-31(25)28-19)20-3-5-23(6-4-20)32-16-15-30-13-11-29(2)12-14-30/h3-10,17-18H,11-16H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Inhibition of BMP4 (unknown origin)-induced phosphorylation of SMAD 1/5/8 by cytoblot cellular ELISA				Bioorg Med Chem Lett 18: 4388-92 (2008) Article DOI: 10.1016/j.bmcl.2008.06.052 BindingDB Entry DOI: 10.7270/Q2BR8S0V
					More data for this Ligand-Target Pair
Bone morphogenetic protein 4 (Homo sapiens (Human))	BDBM50261980 (3-(6-(4-methoxyphenyl)pyrazolo[1,5-a]pyrimidin-3-y...) Show SMILES COc1ccc(cc1)-c1cnc2c(cnn2c1)-c1cnc2ccccc2c1 Show InChI InChI=1S/C22H16N4O/c1-27-19-8-6-15(7-9-19)18-12-24-22-20(13-25-26(22)14-18)17-10-16-4-2-3-5-21(16)23-11-17/h2-14H,1H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Inhibition of BMP4 (unknown origin)-induced phosphorylation of SMAD 1/5/8 by cytoblot cellular ELISA				Bioorg Med Chem Lett 18: 4388-92 (2008) Article DOI: 10.1016/j.bmcl.2008.06.052 BindingDB Entry DOI: 10.7270/Q2BR8S0V
					More data for this Ligand-Target Pair