Compile Data Set for Download or QSAR

Found 5266 hits with Last Name = 'fischer' and Initial = 'j'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(2) dopamine receptor (Homo sapiens (Human))	BDBM21397 (8-[4-(4-fluorophenyl)-4-keto-butyl]-1-phenyl-1,3,8...) Show SMILES Fc1ccc(cc1)C(=O)CCCN1CCC2(CC1)N(CNC2=O)c1ccccc1 Show InChI InChI=1S/C23H26FN3O2/c24-19-10-8-18(9-11-19)21(28)7-4-14-26-15-12-23(13-16-26)22(29)25-17-27(23)20-5-2-1-3-6-20/h1-3,5-6,8-11H,4,7,12-17H2,(H,25,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	0.125	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health Sciences University Curated by PDSP Ki Database									Proc Natl Acad Sci U S A 86: 9762-6 (1989) Article DOI: 10.1073/pnas.86.24.9762 BindingDB Entry DOI: 10.7270/Q2W66J87
					More data for this Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase [139-480,S378A,S381A,T450D,S473D] (Homo sapiens (Human))	BDBM15131 (5-indazolyl pyridine 3 | 5-{5-[(2S)-2-amino-3-(1H-...) Show SMILES Cc1n[nH]c2ccc(cc12)-c1cncc(OC[C@@H](N)Cc2c[nH]c3ccccc23)c1 |r| Show InChI InChI=1S/C24H23N5O/c1-15-22-10-16(6-7-24(22)29-28-15)17-9-20(13-26-11-17)30-14-19(25)8-18-12-27-23-5-3-2-4-21(18)23/h2-7,9-13,19,27H,8,14,25H2,1H3,(H,28,29)/t19-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	0.160	-55.3	n/a	n/a	n/a	n/a	n/a	7.5	22
Abbott Laboratories					Assay Description The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...				Bioorg Med Chem Lett 16: 3740-4 (2006) Article DOI: 10.1016/j.bmcl.2006.04.046 BindingDB Entry DOI: 10.7270/Q2ZP44C9
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50041259 (CHEMBL19355 | Phenethyl-(5-phenyl-pentyl)-amine) Show SMILES C(CCNCCc1ccccc1)CCc1ccccc1 Show InChI InChI=1S/C19H25N/c1-4-10-18(11-5-1)12-8-3-9-16-20-17-15-19-13-6-2-7-14-19/h1-2,4-7,10-11,13-14,20H,3,8-9,12,15-17H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	0.170	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Binding affinity against sigma-1 receptor of guinea pig brain membranes using [3H]-pentazocine as radioligand				J Med Chem 37: 1214-9 (1994) BindingDB Entry DOI: 10.7270/Q29P30QV
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50041268 (Benzyl-methyl-(5-phenyl-pentyl)-amine | CHEMBL1931...) Show SMILES CN(CCCCCc1ccccc1)Cc1ccccc1 Show InChI InChI=1S/C19H25N/c1-20(17-19-14-7-3-8-15-19)16-10-4-9-13-18-11-5-2-6-12-18/h2-3,5-8,11-12,14-15H,4,9-10,13,16-17H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	0.190	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Binding affinity against sigma-1 receptor of guinea pig brain membranes using [3H]-pentazocine as radioligand				J Med Chem 37: 1214-9 (1994) BindingDB Entry DOI: 10.7270/Q29P30QV
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50041246 (CHEMBL19544 | Methyl-phenethyl-(5-phenyl-pentyl)-a...) Show SMILES CN(CCCCCc1ccccc1)CCc1ccccc1 Show InChI InChI=1S/C20H27N/c1-21(18-16-20-14-7-3-8-15-20)17-10-4-9-13-19-11-5-2-6-12-19/h2-3,5-8,11-12,14-15H,4,9-10,13,16-18H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	0.25	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Binding affinity against sigma-1 receptor of guinea pig brain membranes using [3H]-pentazocine as radioligand				J Med Chem 37: 1214-9 (1994) BindingDB Entry DOI: 10.7270/Q29P30QV
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50041277 ((5-Cyclohexyl-pentyl)-dimethyl-amine | CHEMBL20036) Show SMILES CN(C)CCCCCC1CCCCC1 Show InChI InChI=1S/C13H27N/c1-14(2)12-8-4-7-11-13-9-5-3-6-10-13/h13H,3-12H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	0.260	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Binding affinity against sigma-1 receptor of guinea pig brain membranes using [3H]-pentazocine as radioligand				J Med Chem 37: 1214-9 (1994) BindingDB Entry DOI: 10.7270/Q29P30QV
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50041257 ((5-Phenyl-pentyl)-(3-phenyl-propyl)-amine | CHEMBL...) Show SMILES C(CCNCCCc1ccccc1)CCc1ccccc1 Show InChI InChI=1S/C20H27N/c1-4-11-19(12-5-1)15-8-3-9-17-21-18-10-16-20-13-6-2-7-14-20/h1-2,4-7,11-14,21H,3,8-10,15-18H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	0.280	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Binding affinity against sigma-1 receptor of guinea pig brain membranes using [3H]-pentazocine as radioligand				J Med Chem 37: 1214-9 (1994) BindingDB Entry DOI: 10.7270/Q29P30QV
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50041275 (CHEMBL20348 | Methyl-(5-phenyl-pentyl)-propyl-amin...) Show SMILES CCCN(C)CCCCCc1ccccc1 Show InChI InChI=1S/C15H25N/c1-3-13-16(2)14-9-5-8-12-15-10-6-4-7-11-15/h4,6-7,10-11H,3,5,8-9,12-14H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	0.290	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Binding affinity against sigma-1 receptor of guinea pig brain membranes using [3H]-pentazocine as radioligand				J Med Chem 37: 1214-9 (1994) BindingDB Entry DOI: 10.7270/Q29P30QV
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50041243 (Benzyl-(5-phenyl-pentyl)-amine | CHEMBL19315) Show SMILES C(CCNCc1ccccc1)CCc1ccccc1 Show InChI InChI=1S/C18H23N/c1-4-10-17(11-5-1)12-8-3-9-15-19-16-18-13-6-2-7-14-18/h1-2,4-7,10-11,13-14,19H,3,8-9,12,15-16H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	0.320	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Binding affinity against sigma-1 receptor of guinea pig brain membranes using [3H]-pentazocine as radioligand				J Med Chem 37: 1214-9 (1994) BindingDB Entry DOI: 10.7270/Q29P30QV
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50000069 (CHEMBL20377 | [2-(3,4-Dichloro-phenyl)-ethyl]-meth...) Show SMILES CN(CCN1CCCC1)CCc1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C15H22Cl2N2/c1-18(10-11-19-7-2-3-8-19)9-6-13-4-5-14(16)15(17)12-13/h4-5,12H,2-3,6-11H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	PubMed	0.340	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Binding affinity against [3H]-3-PPP labelled sigma sites				J Med Chem 37: 1214-9 (1994) BindingDB Entry DOI: 10.7270/Q29P30QV
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM21397 (8-[4-(4-fluorophenyl)-4-keto-butyl]-1-phenyl-1,3,8...) Show SMILES Fc1ccc(cc1)C(=O)CCCN1CCC2(CC1)N(CNC2=O)c1ccccc1 Show InChI InChI=1S/C23H26FN3O2/c24-19-10-8-18(9-11-19)21(28)7-4-14-26-15-12-23(13-16-26)22(29)25-17-27(23)20-5-2-1-3-6-20/h1-3,5-6,8-11H,4,7,12-17H2,(H,25,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	0.350	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health Sciences University Curated by PDSP Ki Database									Proc Natl Acad Sci U S A 86: 9762-6 (1989) Article DOI: 10.1073/pnas.86.24.9762 BindingDB Entry DOI: 10.7270/Q2W66J87
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50041255 (CHEMBL19637 | Methyl-(5-phenyl-pentyl)-(3-phenyl-p...) Show SMILES CN(CCCCCc1ccccc1)CCCc1ccccc1 Show InChI InChI=1S/C21H29N/c1-22(19-11-17-21-14-7-3-8-15-21)18-10-4-9-16-20-12-5-2-6-13-20/h2-3,5-8,12-15H,4,9-11,16-19H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	0.380	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Binding affinity against sigma-1 receptor of guinea pig brain membranes using [3H]-pentazocine as radioligand				J Med Chem 37: 1214-9 (1994) BindingDB Entry DOI: 10.7270/Q29P30QV
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50039200 ((4-Phenyl-butyl)-(5-phenyl-pentyl)-amine | CHEMBL2...) Show SMILES C(CCNCCCCc1ccccc1)CCc1ccccc1 Show InChI InChI=1S/C21H29N/c1-4-12-20(13-5-1)16-8-3-10-18-22-19-11-9-17-21-14-6-2-7-15-21/h1-2,4-7,12-15,22H,3,8-11,16-19H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	0.480	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Binding affinity against sigma-1 receptor of guinea pig brain membranes using [3H]-pentazocine as radioligand				J Med Chem 37: 1214-9 (1994) BindingDB Entry DOI: 10.7270/Q29P30QV
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50041251 (1-(5-Phenyl-pentyl)-piperidine | CHEMBL20188) Show SMILES C(CCN1CCCCC1)CCc1ccccc1 Show InChI InChI=1S/C16H25N/c1-4-10-16(11-5-1)12-6-2-7-13-17-14-8-3-9-15-17/h1,4-5,10-11H,2-3,6-9,12-15H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	0.480	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Binding affinity against sigma-1 receptor of guinea pig brain membranes using [3H]-pentazocine as radioligand				J Med Chem 37: 1214-9 (1994) BindingDB Entry DOI: 10.7270/Q29P30QV
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50041266 (((S)-1-Methyl-2-phenyl-ethyl)-(5-phenyl-pentyl)-am...) Show SMILES C[C@@H](Cc1ccccc1)NCCCCCc1ccccc1 Show InChI InChI=1S/C20H27N/c1-18(17-20-14-7-3-8-15-20)21-16-10-4-9-13-19-11-5-2-6-12-19/h2-3,5-8,11-12,14-15,18,21H,4,9-10,13,16-17H2,1H3/t18-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Binding affinity against sigma-1 receptor of guinea pig brain membranes using [3H]-pentazocine as radioligand				J Med Chem 37: 1214-9 (1994) BindingDB Entry DOI: 10.7270/Q29P30QV
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM21397 (8-[4-(4-fluorophenyl)-4-keto-butyl]-1-phenyl-1,3,8...) Show SMILES Fc1ccc(cc1)C(=O)CCCN1CCC2(CC1)N(CNC2=O)c1ccccc1 Show InChI InChI=1S/C23H26FN3O2/c24-19-10-8-18(9-11-19)21(28)7-4-14-26-15-12-23(13-16-26)22(29)25-17-27(23)20-5-2-1-3-6-20/h1-3,5-6,8-11H,4,7,12-17H2,(H,25,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	0.560	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health Sciences University Curated by PDSP Ki Database									Proc Natl Acad Sci U S A 86: 9762-6 (1989) Article DOI: 10.1073/pnas.86.24.9762 BindingDB Entry DOI: 10.7270/Q2W66J87
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50041264 (1-(5-Phenyl-pentyl)-pyrrolidine | CHEMBL277462) Show SMILES C(CCN1CCCC1)CCc1ccccc1 Show InChI InChI=1S/C15H23N/c1-3-9-15(10-4-1)11-5-2-6-12-16-13-7-8-14-16/h1,3-4,9-10H,2,5-8,11-14H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	0.760	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Binding affinity against sigma-1 receptor of guinea pig brain membranes using [3H]-pentazocine as radioligand				J Med Chem 37: 1214-9 (1994) BindingDB Entry DOI: 10.7270/Q29P30QV
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50007400 (4-Phenyl-1-(4-phenyl-butyl)-piperidine | 4-Phenyl-...) Show SMILES C(CCc1ccccc1)CN1CCC(CC1)c1ccccc1 Show InChI InChI=1S/C21H27N/c1-3-9-19(10-4-1)11-7-8-16-22-17-14-21(15-18-22)20-12-5-2-6-13-20/h1-6,9-10,12-13,21H,7-8,11,14-18H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	PubMed	0.800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description The compound was tested for its binding affinity towards Sigma opioid receptor in guinea pig brain membranes				J Med Chem 34: 3360-5 (1992) BindingDB Entry DOI: 10.7270/Q2MC8XZR
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50041263 (Benzyl-(5-cyclohexyl-pentyl)-amine | CHEMBL416730) Show SMILES C(CCNCc1ccccc1)CCC1CCCCC1 Show InChI InChI=1S/C18H29N/c1-4-10-17(11-5-1)12-8-3-9-15-19-16-18-13-6-2-7-14-18/h2,6-7,13-14,17,19H,1,3-5,8-12,15-16H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	0.810	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Binding affinity against sigma-1 receptor of guinea pig brain membranes using [3H]-pentazocine as radioligand				J Med Chem 37: 1214-9 (1994) BindingDB Entry DOI: 10.7270/Q29P30QV
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50007396 (4-Phenyl-1-(5-phenyl-pentyl)-piperidine | CHEMBL11...) Show SMILES C(CCN1CCC(CC1)c1ccccc1)CCc1ccccc1 Show InChI InChI=1S/C22H29N/c1-4-10-20(11-5-1)12-6-3-9-17-23-18-15-22(16-19-23)21-13-7-2-8-14-21/h1-2,4-5,7-8,10-11,13-14,22H,3,6,9,12,15-19H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	0.900	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description The compound was tested for its binding affinity towards sigma receptor in guinea pig brain membranes				J Med Chem 34: 3360-5 (1992) BindingDB Entry DOI: 10.7270/Q2MC8XZR
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50041237 (((R)-1-Methyl-2-phenyl-ethyl)-(5-phenyl-pentyl)-am...) Show SMILES C[C@H](Cc1ccccc1)NCCCCCc1ccccc1 Show InChI InChI=1S/C20H27N/c1-18(17-20-14-7-3-8-15-20)21-16-10-4-9-13-19-11-5-2-6-12-19/h2-3,5-8,11-12,14-15,18,21H,4,9-10,13,16-17H2,1H3/t18-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	0.900	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Binding affinity against sigma-1 receptor of guinea pig brain membranes using [3H]-pentazocine as radioligand				J Med Chem 37: 1214-9 (1994) BindingDB Entry DOI: 10.7270/Q29P30QV
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50008735 ((+)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,...) Show SMILES CC(C)(C)[C@]1(O)CCN2C[C@H]3c4ccccc4CCc4cccc([C@@H]2C1)c34 Show InChI InChI=1S/C25H31NO/c1-24(2,3)25(27)13-14-26-16-21-19-9-5-4-7-17(19)11-12-18-8-6-10-20(23(18)21)22(26)15-25/h4-10,21-22,27H,11-16H2,1-3H3/t21-,22-,25-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.940	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health Sciences University Curated by PDSP Ki Database									Proc Natl Acad Sci U S A 86: 9762-6 (1989) Article DOI: 10.1073/pnas.86.24.9762 BindingDB Entry DOI: 10.7270/Q2W66J87
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50007393 (4-Phenyl-1-(3-phenyl-propyl)-piperidine | CHEMBL11...) Show SMILES C(CN1CCC(CC1)c1ccccc1)Cc1ccccc1 Show InChI InChI=1S/C20H25N/c1-3-8-18(9-4-1)10-7-15-21-16-13-20(14-17-21)19-11-5-2-6-12-19/h1-6,8-9,11-12,20H,7,10,13-17H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	1.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description The compound was tested for its binding affinity towards Sigma opioid receptor in guinea pig brain membranes				J Med Chem 34: 3360-5 (1992) BindingDB Entry DOI: 10.7270/Q2MC8XZR
					More data for this Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase [139-480,S378A,S381A,T450D,S473D] (Homo sapiens (Human))	BDBM15136 (5-indazolyl pyridine 11e | 5-{5-[(2S)-2-amino-3-(2...) Show SMILES COc1ccc2ccccc2c1C[C@H](N)COc1cncc(c1)-c1ccc2[nH]nc(C)c2c1 |r| Show InChI InChI=1S/C27H26N4O2/c1-17-24-12-19(7-9-26(24)31-30-17)20-11-22(15-29-14-20)33-16-21(28)13-25-23-6-4-3-5-18(23)8-10-27(25)32-2/h3-12,14-15,21H,13,16,28H2,1-2H3,(H,30,31)/t21-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	1.10	-50.6	n/a	n/a	n/a	n/a	n/a	7.5	22
Abbott Laboratories					Assay Description The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...				Bioorg Med Chem Lett 16: 3740-4 (2006) Article DOI: 10.1016/j.bmcl.2006.04.046 BindingDB Entry DOI: 10.7270/Q2ZP44C9
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50008735 ((+)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,...) Show SMILES CC(C)(C)[C@]1(O)CCN2C[C@H]3c4ccccc4CCc4cccc([C@@H]2C1)c34 Show InChI InChI=1S/C25H31NO/c1-24(2,3)25(27)13-14-26-16-21-19-9-5-4-7-17(19)11-12-18-8-6-10-20(23(18)21)22(26)15-25/h4-10,21-22,27H,11-16H2,1-3H3/t21-,22-,25-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health Sciences University Curated by PDSP Ki Database									Proc Natl Acad Sci U S A 86: 9762-6 (1989) Article DOI: 10.1073/pnas.86.24.9762 BindingDB Entry DOI: 10.7270/Q2W66J87
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50041269 (CHEMBL20517 | Methyl-((R)-1-methyl-2-phenyl-ethyl)...) Show SMILES C[C@H](Cc1ccccc1)N(C)CCCc1ccccc1 Show InChI InChI=1S/C19H25N/c1-17(16-19-12-7-4-8-13-19)20(2)15-9-14-18-10-5-3-6-11-18/h3-8,10-13,17H,9,14-16H2,1-2H3/t17-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	1.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Binding affinity against sigma-1 receptor of guinea pig brain membranes using [3H]-pentazocine as radioligand				J Med Chem 37: 1214-9 (1994) BindingDB Entry DOI: 10.7270/Q29P30QV
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50041273 (CHEMBL19797 | Phenethyl-(7-phenyl-heptyl)-amine) Show SMILES C(CCCNCCc1ccccc1)CCCc1ccccc1 Show InChI InChI=1S/C21H29N/c1(2-6-12-20-13-7-4-8-14-20)3-11-18-22-19-17-21-15-9-5-10-16-21/h4-5,7-10,13-16,22H,1-3,6,11-12,17-19H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	1.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Binding affinity against sigma-1 receptor of guinea pig brain membranes using [3H]-pentazocine as radioligand				J Med Chem 37: 1214-9 (1994) BindingDB Entry DOI: 10.7270/Q29P30QV
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50008735 ((+)-3-(tert-butyl)-(3S,4aS,13bS)-2,3,4,4a,8,9,13b,...) Show SMILES CC(C)(C)[C@]1(O)CCN2C[C@H]3c4ccccc4CCc4cccc([C@@H]2C1)c34 Show InChI InChI=1S/C25H31NO/c1-24(2,3)25(27)13-14-26-16-21-19-9-5-4-7-17(19)11-12-18-8-6-10-20(23(18)21)22(26)15-25/h4-10,21-22,27H,11-16H2,1-3H3/t21-,22-,25-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health Sciences University Curated by PDSP Ki Database									Proc Natl Acad Sci U S A 86: 9762-6 (1989) Article DOI: 10.1073/pnas.86.24.9762 BindingDB Entry DOI: 10.7270/Q2W66J87
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50035131 ((+)-(6R,11S)-6,11-dimethyl-3-(3-methyl-but-2-enyl)...) Show SMILES [#6]-[#6@@H]1-[#6@@H]-2-[#6]-c3ccc(-[#8])cc3[C@@]1([#6])[#6]-[#6]-[#7]-2-[#6]\[#6]=[#6](/[#6])-[#6] |r,TLB:16:15:10.4.3:1| Show InChI InChI=1S/C19H27NO/c1-13(2)7-9-20-10-8-19(4)14(3)18(20)11-15-5-6-16(21)12-17(15)19/h5-7,12,14,18,21H,8-11H2,1-4H3/t14-,18+,19+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Similars	PDB PubMed	1.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Tested for binding affinity against sigma 1 receptor				J Med Chem 37: 1214-9 (1994) BindingDB Entry DOI: 10.7270/Q29P30QV
					More data for this Ligand-Target Pair				3D Structure (crystal)
RAC-alpha serine/threonine-protein kinase [139-480,S378A,S381A,T450D,S473D] (Homo sapiens (Human))	BDBM15067 ((2S)-1-(1H-indol-3-yl)-3-(5-isoquinolin-6-ylpyridi...) Show SMILES N[C@H](COc1cncc(c1)-c1ccc2cnccc2c1)Cc1c[nH]c2ccccc12 |r| Show InChI InChI=1S/C25H22N4O/c26-22(10-21-14-29-25-4-2-1-3-24(21)25)16-30-23-11-20(13-28-15-23)17-5-6-19-12-27-8-7-18(19)9-17/h1-9,11-15,22,29H,10,16,26H2/t22-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	2	-49.2	n/a	n/a	n/a	n/a	n/a	7.5	22
Abbott Laboratories					Assay Description The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...				Bioorg Med Chem Lett 16: 3740-4 (2006) Article DOI: 10.1016/j.bmcl.2006.04.046 BindingDB Entry DOI: 10.7270/Q2ZP44C9
					More data for this Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase [139-480,S378A,S381A,T450D,S473D] (Homo sapiens (Human))	BDBM15132 (5-indazolyl pyridine 11a | 5-{5-[(2S)-2-amino-3-(2...) Show SMILES Cc1n[nH]c2ccc(cc12)-c1cncc(OC[C@@H](N)Cc2c(C)[nH]c3ccccc23)c1 |r| Show InChI InChI=1S/C25H25N5O/c1-15-22(21-5-3-4-6-24(21)28-15)11-19(26)14-31-20-9-18(12-27-13-20)17-7-8-25-23(10-17)16(2)29-30-25/h3-10,12-13,19,28H,11,14,26H2,1-2H3,(H,29,30)/t19-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	2.10	-49.0	n/a	n/a	n/a	n/a	n/a	7.5	22
Abbott Laboratories					Assay Description The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...				Bioorg Med Chem Lett 16: 3740-4 (2006) Article DOI: 10.1016/j.bmcl.2006.04.046 BindingDB Entry DOI: 10.7270/Q2ZP44C9
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50041253 (Benzyl-(7-phenyl-heptyl)-amine | CHEMBL19850) Show SMILES C(CCCNCc1ccccc1)CCCc1ccccc1 Show InChI InChI=1S/C20H27N/c1(2-6-12-19-13-7-4-8-14-19)3-11-17-21-18-20-15-9-5-10-16-20/h4-5,7-10,13-16,21H,1-3,6,11-12,17-18H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	2.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Binding affinity against sigma-1 receptor of guinea pig brain membranes using [3H]-pentazocine as radioligand				J Med Chem 37: 1214-9 (1994) BindingDB Entry DOI: 10.7270/Q29P30QV
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM21398 (4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...) Show SMILES OC1(CCN(CCCC(=O)c2ccc(F)cc2)CC1)c1ccc(Cl)cc1 Show InChI InChI=1S/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	2.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Oregon Health Sciences University Curated by PDSP Ki Database									Proc Natl Acad Sci U S A 86: 9762-6 (1989) Article DOI: 10.1073/pnas.86.24.9762 BindingDB Entry DOI: 10.7270/Q2W66J87
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50007401 (1-Phenyl-4-(4-phenyl-butyl)-piperazine | CHEMBL858...) Show SMILES C(CCc1ccccc1)CN1CCN(CC1)c1ccccc1 Show InChI InChI=1S/C20H26N2/c1-3-9-19(10-4-1)11-7-8-14-21-15-17-22(18-16-21)20-12-5-2-6-13-20/h1-6,9-10,12-13H,7-8,11,14-18H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	2.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Binding affinity of the compound towards sigma receptor in guinea pig brain membranes using [3H]-DTG as radioligand				J Med Chem 34: 3360-5 (1992) BindingDB Entry DOI: 10.7270/Q2MC8XZR
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50368228 (CHEMBL1907650) Show SMILES C[C@@H](Cc1ccccc1)N(C)CCCCCc1ccccc1 |r| Show InChI InChI=1S/C21H29N/c1-19(18-21-15-8-4-9-16-21)22(2)17-11-5-10-14-20-12-6-3-7-13-20/h3-4,6-9,12-13,15-16,19H,5,10-11,14,17-18H2,1-2H3/t19-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Binding affinity towards sigma opioid receptor in guinea pig cerebral homogenate using [3H]DTG as radioligand				J Med Chem 34: 1094-8 (1991) BindingDB Entry DOI: 10.7270/Q28C9WV8
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50041247 (CHEMBL280111 | Phenethyl-(4-phenyl-butyl)-amine) Show SMILES C(CCc1ccccc1)CNCCc1ccccc1 Show InChI InChI=1S/C18H23N/c1-3-9-17(10-4-1)13-7-8-15-19-16-14-18-11-5-2-6-12-18/h1-6,9-12,19H,7-8,13-16H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	2.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Binding affinity against sigma-1 receptor of guinea pig brain membranes using [3H]-pentazocine as radioligand				J Med Chem 37: 1214-9 (1994) BindingDB Entry DOI: 10.7270/Q29P30QV
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50041241 ((1-Benzyl-butyl)-(4-phenyl-butyl)-amine | CHEMBL43...) Show SMILES CCCC(Cc1ccccc1)NCCCCc1ccccc1 Show InChI InChI=1S/C21H29N/c1-2-11-21(18-20-15-7-4-8-16-20)22-17-10-9-14-19-12-5-3-6-13-19/h3-8,12-13,15-16,21-22H,2,9-11,14,17-18H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	2.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Binding affinity against sigma-1 receptor of guinea pig brain membranes using [3H]-pentazocine as radioligand				J Med Chem 37: 1214-9 (1994) BindingDB Entry DOI: 10.7270/Q29P30QV
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50007409 (1-Naphthalen-2-yl-4-(3-phenyl-propyl)-piperazine |...) Show SMILES C(CN1CCN(CC1)c1ccc2ccccc2c1)Cc1ccccc1 Show InChI InChI=1S/C23H26N2/c1-2-7-20(8-3-1)9-6-14-24-15-17-25(18-16-24)23-13-12-21-10-4-5-11-22(21)19-23/h1-5,7-8,10-13,19H,6,9,14-18H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	2.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Binding affinity of the compound towards sigma receptor in guinea pig brain membranes using [3H]-DTG as radioligand				J Med Chem 34: 3360-5 (1992) BindingDB Entry DOI: 10.7270/Q2MC8XZR
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50007410 (1-(4-Chloro-phenyl)-4-(3-phenyl-propyl)-piperazine...) Show SMILES Clc1ccc(cc1)N1CCN(CCCc2ccccc2)CC1 Show InChI InChI=1S/C19H23ClN2/c20-18-8-10-19(11-9-18)22-15-13-21(14-16-22)12-4-7-17-5-2-1-3-6-17/h1-3,5-6,8-11H,4,7,12-16H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	2.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Binding affinity of the compound towards sigma receptor in guinea pig brain membranes using [3H]-DTG as radioligand				J Med Chem 34: 3360-5 (1992) BindingDB Entry DOI: 10.7270/Q2MC8XZR
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50007398 (4-Phenyl-1-(3-phenyl-propyl)-piperidin-4-ol | 4-ph...) Show SMILES OC1(CCN(CCCc2ccccc2)CC1)c1ccccc1 Show InChI InChI=1S/C20H25NO/c22-20(19-11-5-2-6-12-19)13-16-21(17-14-20)15-7-10-18-8-3-1-4-9-18/h1-6,8-9,11-12,22H,7,10,13-17H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description The compound was tested for its binding affinity towards Sigma opioid receptor in guinea pig brain membranes				J Med Chem 34: 3360-5 (1992) BindingDB Entry DOI: 10.7270/Q2MC8XZR
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Rattus norvegicus (rat))	BDBM50295029 (5-(4-Cyclopropylphenyl)-1-(2,4-dichlorophenyl)-4-m...) Show SMILES COc1c(nn(c1-c1ccc(cc1)C1CC1)-c1ccc(Cl)cc1Cl)C(=O)NN1CCCCC1 Show InChI InChI=1S/C25H26Cl2N4O2/c1-33-24-22(25(32)29-30-13-3-2-4-14-30)28-31(21-12-11-19(26)15-20(21)27)23(24)18-9-7-17(8-10-18)16-5-6-16/h7-12,15-16H,2-6,13-14H2,1H3,(H,29,32)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gedeon Richter Plc Curated by ChEMBL					Assay Description Displacement of [3H]SR141716A from CB1 receptor in rat cerebellum by scintillation spectrometry				J Med Chem 52: 4329-37 (2009) Article DOI: 10.1021/jm900179y BindingDB Entry DOI: 10.7270/Q2NG4QN2
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Rattus norvegicus (rat))	BDBM50295024 (5-(4-Cyclopropylphenyl)-1-(2,4-dichlorophenyl)-4-m...) Show SMILES Cc1c(nn(c1-c1ccc(cc1)C1CC1)-c1ccc(Cl)cc1Cl)C(=O)NN1CCCCC1 Show InChI InChI=1S/C25H26Cl2N4O/c1-16-23(25(32)29-30-13-3-2-4-14-30)28-31(22-12-11-20(26)15-21(22)27)24(16)19-9-7-18(8-10-19)17-5-6-17/h7-12,15,17H,2-6,13-14H2,1H3,(H,29,32)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gedeon Richter Plc Curated by ChEMBL					Assay Description Displacement of [3H]SR141716A from CB1 receptor in rat cerebellum by scintillation spectrometry				J Med Chem 52: 4329-37 (2009) Article DOI: 10.1021/jm900179y BindingDB Entry DOI: 10.7270/Q2NG4QN2
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Rattus norvegicus (rat))	BDBM50295040 (5-(4-Cyclopropylphenyl)-1-(2-chloro-4-bromophenyl)...) Show SMILES Cc1c(nn(c1-c1ccc(cc1)C1CC1)-c1ccc(Br)cc1Cl)C(=O)NN1CCCCC1 Show InChI InChI=1S/C25H26BrClN4O/c1-16-23(25(32)29-30-13-3-2-4-14-30)28-31(22-12-11-20(26)15-21(22)27)24(16)19-9-7-18(8-10-19)17-5-6-17/h7-12,15,17H,2-6,13-14H2,1H3,(H,29,32)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gedeon Richter Plc Curated by ChEMBL					Assay Description Displacement of [3H]SR141716A from CB1 receptor in rat cerebellum by scintillation spectrometry				J Med Chem 52: 4329-37 (2009) Article DOI: 10.1021/jm900179y BindingDB Entry DOI: 10.7270/Q2NG4QN2
					More data for this Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase [139-480,S378A,S381A,T450D,S473D] (Homo sapiens (Human))	BDBM15134 (5-indazolyl pyridine 11c | 5-{5-[(2S)-2-amino-3-(n...) Show SMILES Cc1n[nH]c2ccc(cc12)-c1cncc(OC[C@@H](N)Cc2ccc3ccccc3c2)c1 |r| Show InChI InChI=1S/C26H24N4O/c1-17-25-13-21(8-9-26(25)30-29-17)22-12-24(15-28-14-22)31-16-23(27)11-18-6-7-19-4-2-3-5-20(19)10-18/h2-10,12-15,23H,11,16,27H2,1H3,(H,29,30)/t23-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	3.20	-48.0	n/a	n/a	n/a	n/a	n/a	7.5	22
Abbott Laboratories					Assay Description The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...				Bioorg Med Chem Lett 16: 3740-4 (2006) Article DOI: 10.1016/j.bmcl.2006.04.046 BindingDB Entry DOI: 10.7270/Q2ZP44C9
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50006969 (CHEMBL20768 | [2-(4-Ethoxy-phenyl)-1-methyl-ethyl]...) Show SMILES CCOc1ccc(CC(C)NCCCc2ccccc2)cc1 Show InChI InChI=1S/C20H27NO/c1-3-22-20-13-11-19(12-14-20)16-17(2)21-15-7-10-18-8-5-4-6-9-18/h4-6,8-9,11-14,17,21H,3,7,10,15-16H2,1-2H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	3.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Binding affinity against sigma-1 receptor of guinea pig brain membranes using [3H]-pentazocine as radioligand				J Med Chem 37: 1214-9 (1994) BindingDB Entry DOI: 10.7270/Q29P30QV
					More data for this Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase [139-480,S378A,S381A,T450D,S473D] (Homo sapiens (Human))	BDBM15125 (5-isoquinolinyl pyridine 10d | 6-{5-[(2S)-2-amino-...) Show SMILES N[C@H](COc1cncc(c1)-c1ccc2cnccc2c1)Cc1ccc2ccccc2c1 |r| Show InChI InChI=1S/C27H23N3O/c28-26(12-19-5-6-20-3-1-2-4-21(20)11-19)18-31-27-14-25(16-30-17-27)22-7-8-24-15-29-10-9-23(24)13-22/h1-11,13-17,26H,12,18,28H2/t26-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	3.5	-47.8	n/a	n/a	n/a	n/a	n/a	7.5	22
Abbott Laboratories					Assay Description The kinase assay uses His-Akt1 and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidin-coated FLASH plat...				Bioorg Med Chem Lett 16: 3740-4 (2006) Article DOI: 10.1016/j.bmcl.2006.04.046 BindingDB Entry DOI: 10.7270/Q2ZP44C9
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (Homo sapiens (Human))	BDBM50006981 (CHEMBL19841 | [1-Methyl-2-(3-trifluoromethyl-pheny...) Show SMILES CC(Cc1cccc(c1)C(F)(F)F)NCCCc1ccccc1 Show InChI InChI=1S/C19H22F3N/c1-15(23-12-6-10-16-7-3-2-4-8-16)13-17-9-5-11-18(14-17)19(20,21)22/h2-5,7-9,11,14-15,23H,6,10,12-13H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	3.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Inhibition of [3H]DTG binding to Sigma opioid receptor				J Med Chem 34: 1855-9 (1991) BindingDB Entry DOI: 10.7270/Q2WW7J9Z
					More data for this Ligand-Target Pair
Sigma non-opioid intracellular receptor 1 (RAT)	BDBM50009049 ((+/-)(1-Methyl-2-phenyl-ethyl)-(4-phenyl-butyl)-am...) Show SMILES CC(Cc1ccccc1)NCCCCc1ccccc1 Show InChI InChI=1S/C19H25N/c1-17(16-19-13-6-3-7-14-19)20-15-9-8-12-18-10-4-2-5-11-18/h2-7,10-11,13-14,17,20H,8-9,12,15-16H2,1H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	3.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Binding affinity towards sigma opioid receptor was determined in rat cerebral homogenate using [3H]haloperidol as radioligand				J Med Chem 34: 1094-8 (1991) BindingDB Entry DOI: 10.7270/Q28C9WV8
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Rattus norvegicus (rat))	BDBM50295039 (5-(4-Cyclopropylphenyl)-1-(2,4-dichlorophenyl)-4-e...) Show SMILES CCc1c(nn(c1-c1ccc(cc1)C1CC1)-c1ccc(Cl)cc1Cl)C(=O)NN1CCCCC1 Show InChI InChI=1S/C26H28Cl2N4O/c1-2-21-24(26(33)30-31-14-4-3-5-15-31)29-32(23-13-12-20(27)16-22(23)28)25(21)19-10-8-18(9-11-19)17-6-7-17/h8-13,16-17H,2-7,14-15H2,1H3,(H,30,33)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gedeon Richter Plc Curated by ChEMBL					Assay Description Displacement of [3H]SR141716A from CB1 receptor in rat cerebellum by scintillation spectrometry				J Med Chem 52: 4329-37 (2009) Article DOI: 10.1021/jm900179y BindingDB Entry DOI: 10.7270/Q2NG4QN2
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Rattus norvegicus (rat))	BDBM50295041 (5-(4-Cyclopropylphenyl)-1-(2,4-dichlorophenyl)-4-e...) Show SMILES CCc1c(nn(c1-c1ccc(cc1)C1CC1)-c1ccc(Cl)cc1Cl)C(=O)NN1CCCC1 Show InChI InChI=1S/C25H26Cl2N4O/c1-2-20-23(25(32)29-30-13-3-4-14-30)28-31(22-12-11-19(26)15-21(22)27)24(20)18-9-7-17(8-10-18)16-5-6-16/h7-12,15-16H,2-6,13-14H2,1H3,(H,29,32)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gedeon Richter Plc Curated by ChEMBL					Assay Description Displacement of [3H]SR141716A from CB1 receptor in rat cerebellum by scintillation spectrometry				J Med Chem 52: 4329-37 (2009) Article DOI: 10.1021/jm900179y BindingDB Entry DOI: 10.7270/Q2NG4QN2
					More data for this Ligand-Target Pair

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