Compile Data Set for Download or QSAR

Found 61 hits with Last Name = 'floc''h' and Initial = 'm'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50359779 (CHEMBL1928271) Show SMILES CCN1CCN(CC1)S(=O)(=O)c1cnc(OCC2CC2)c(c1)-c1nc2c(CC)n(CCN3CCOCC3)nc2c(=O)[nH]1 Show InChI InChI=1S/C28H40N8O5S/c1-3-23-24-25(32-36(23)12-9-34-13-15-40-16-14-34)27(37)31-26(30-24)22-17-21(18-29-28(22)41-19-20-5-6-20)42(38,39)35-10-7-33(4-2)8-11-35/h17-18,20H,3-16,19H2,1-2H3,(H,30,31,37)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.260	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of human PDE5 isolated from corpus cavernosum after 30 to 60 mins by scintillation counting method				Bioorg Med Chem 20: 498-509 (2011) Article DOI: 10.1016/j.bmc.2011.10.022 BindingDB Entry DOI: 10.7270/Q2M9094T
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50359773 (CHEMBL1928265) Show SMILES CCCCOc1ncc(cc1-c1nc2c(CC)n(nc2c(=O)[nH]1)C1CCN(CC1)S(C)(=O)=O)S(=O)(=O)N1CCN(CC)CC1 Show InChI InChI=1S/C28H42N8O6S2/c1-5-8-17-42-28-22(18-21(19-29-28)44(40,41)35-15-13-33(7-3)14-16-35)26-30-24-23(6-2)36(32-25(24)27(37)31-26)20-9-11-34(12-10-20)43(4,38)39/h18-20H,5-17H2,1-4H3,(H,30,31,37)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.310	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of human PDE5 isolated from corpus cavernosum after 30 to 60 mins by scintillation counting method				Bioorg Med Chem 20: 498-509 (2011) Article DOI: 10.1016/j.bmc.2011.10.022 BindingDB Entry DOI: 10.7270/Q2M9094T
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50359795 (CHEMBL1928258) Show SMILES CCCOc1ncc(cc1-c1nc2c(CC)n(CCOC)nc2c(=O)[nH]1)S(=O)(=O)N1CCN(CC)CC1 Show InChI InChI=1S/C24H35N7O5S/c1-5-13-36-24-18(15-17(16-25-24)37(33,34)30-10-8-29(7-3)9-11-30)22-26-20-19(6-2)31(12-14-35-4)28-21(20)23(32)27-22/h15-16H,5-14H2,1-4H3,(H,26,27,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.690	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of human PDE5 isolated from corpus cavernosum after 30 to 60 mins by scintillation counting method				Bioorg Med Chem 20: 498-509 (2011) Article DOI: 10.1016/j.bmc.2011.10.022 BindingDB Entry DOI: 10.7270/Q2M9094T
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50359767 (CHEMBL1928259) Show SMILES CCN1CCN(CC1)S(=O)(=O)c1cnc(OCC(C)C)c(c1)-c1nc2c(CC)n(CCOC)nc2c(=O)[nH]1 Show InChI InChI=1S/C25H37N7O5S/c1-6-20-21-22(29-32(20)12-13-36-5)24(33)28-23(27-21)19-14-18(15-26-25(19)37-16-17(3)4)38(34,35)31-10-8-30(7-2)9-11-31/h14-15,17H,6-13,16H2,1-5H3,(H,27,28,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.690	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of human PDE5 isolated from corpus cavernosum after 30 to 60 mins by scintillation counting method				Bioorg Med Chem 20: 498-509 (2011) Article DOI: 10.1016/j.bmc.2011.10.022 BindingDB Entry DOI: 10.7270/Q2M9094T
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50359774 (CHEMBL1928266) Show SMILES CCCCOc1ncc(cc1-c1nc2c(CC)n(nc2c(=O)[nH]1)C1CCN(C)CC1)S(=O)(=O)N1CCN(CC)CC1 Show InChI InChI=1S/C28H42N8O4S/c1-5-8-17-40-28-22(18-21(19-29-28)41(38,39)35-15-13-34(7-3)14-16-35)26-30-24-23(6-2)36(32-25(24)27(37)31-26)20-9-11-33(4)12-10-20/h18-20H,5-17H2,1-4H3,(H,30,31,37)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.740	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of human PDE5 isolated from corpus cavernosum after 30 to 60 mins by scintillation counting method				Bioorg Med Chem 20: 498-509 (2011) Article DOI: 10.1016/j.bmc.2011.10.022 BindingDB Entry DOI: 10.7270/Q2M9094T
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50359768 (CHEMBL1928260) Show SMILES CCN1CCN(CC1)S(=O)(=O)c1cnc(OCc2ccccn2)c(c1)-c1nc2c(CC)n(CCOC)nc2c(=O)[nH]1 Show InChI InChI=1S/C27H34N8O5S/c1-4-22-23-24(32-35(22)14-15-39-3)26(36)31-25(30-23)21-16-20(41(37,38)34-12-10-33(5-2)11-13-34)17-29-27(21)40-18-19-8-6-7-9-28-19/h6-9,16-17H,4-5,10-15,18H2,1-3H3,(H,30,31,36)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.75	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of human PDE5 isolated from corpus cavernosum after 30 to 60 mins by scintillation counting method				Bioorg Med Chem 20: 498-509 (2011) Article DOI: 10.1016/j.bmc.2011.10.022 BindingDB Entry DOI: 10.7270/Q2M9094T
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50359777 (CHEMBL1928269) Show SMILES CCCCOc1ncc(cc1-c1nc2c(CC)n(nc2c(=O)[nH]1)C1CN(C)C1)S(=O)(=O)N1CCN(CC)CC1 Show InChI InChI=1S/C26H38N8O4S/c1-5-8-13-38-26-20(14-19(15-27-26)39(36,37)33-11-9-32(7-3)10-12-33)24-28-22-21(6-2)34(18-16-31(4)17-18)30-23(22)25(35)29-24/h14-15,18H,5-13,16-17H2,1-4H3,(H,28,29,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.780	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of human PDE5 isolated from corpus cavernosum after 30 to 60 mins by scintillation counting method				Bioorg Med Chem 20: 498-509 (2011) Article DOI: 10.1016/j.bmc.2011.10.022 BindingDB Entry DOI: 10.7270/Q2M9094T
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50359778 (CHEMBL1928270) Show SMILES CCOc1ncc(cc1-c1nc2c(CC)n(CCN3CCOCC3)nc2c(=O)[nH]1)S(=O)(=O)N1CCN(CC)CC1 Show InChI InChI=1S/C26H38N8O5S/c1-4-21-22-23(30-34(21)12-9-32-13-15-38-16-14-32)25(35)29-24(28-22)20-17-19(18-27-26(20)39-6-3)40(36,37)33-10-7-31(5-2)8-11-33/h17-18H,4-16H2,1-3H3,(H,28,29,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.860	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of human PDE5 isolated from corpus cavernosum after 30 to 60 mins by scintillation counting method				Bioorg Med Chem 20: 498-509 (2011) Article DOI: 10.1016/j.bmc.2011.10.022 BindingDB Entry DOI: 10.7270/Q2M9094T
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50359771 (CHEMBL1928263) Show SMILES CCCCOc1ncc(cc1-c1nc2c(CC)n(CCN(C)C)nc2c(=O)[nH]1)S(=O)(=O)N1CCN(CC)CC1 Show InChI InChI=1S/C26H40N8O4S/c1-6-9-16-38-26-20(17-19(18-27-26)39(36,37)33-13-11-32(8-3)12-14-33)24-28-22-21(7-2)34(15-10-31(4)5)30-23(22)25(35)29-24/h17-18H,6-16H2,1-5H3,(H,28,29,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of human PDE5 isolated from corpus cavernosum after 30 to 60 mins by scintillation counting method				Bioorg Med Chem 20: 498-509 (2011) Article DOI: 10.1016/j.bmc.2011.10.022 BindingDB Entry DOI: 10.7270/Q2M9094T
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50359790 (CHEMBL1928253) Show SMILES CCN1CCN(CC1)S(=O)(=O)c1cnc(OCCOC)c(c1)-c1nc2c(CC)n(CC3CC3)nc2c(=O)[nH]1 Show InChI InChI=1S/C25H35N7O5S/c1-4-20-21-22(29-32(20)16-17-6-7-17)24(33)28-23(27-21)19-14-18(15-26-25(19)37-13-12-36-3)38(34,35)31-10-8-30(5-2)9-11-31/h14-15,17H,4-13,16H2,1-3H3,(H,27,28,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of human PDE5 isolated from corpus cavernosum after 30 to 60 mins by scintillation counting method				Bioorg Med Chem 20: 498-509 (2011) Article DOI: 10.1016/j.bmc.2011.10.022 BindingDB Entry DOI: 10.7270/Q2M9094T
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50359789 (CHEMBL1928252) Show SMILES CCN1CCN(CC1)S(=O)(=O)c1cnc(OCCOC)c(c1)-c1nc2c(CC)n(CC(C)C)nc2c(=O)[nH]1 Show InChI InChI=1S/C25H37N7O5S/c1-6-20-21-22(29-32(20)16-17(3)4)24(33)28-23(27-21)19-14-18(15-26-25(19)37-13-12-36-5)38(34,35)31-10-8-30(7-2)9-11-31/h14-15,17H,6-13,16H2,1-5H3,(H,27,28,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of human PDE5 isolated from corpus cavernosum after 30 to 60 mins by scintillation counting method				Bioorg Med Chem 20: 498-509 (2011) Article DOI: 10.1016/j.bmc.2011.10.022 BindingDB Entry DOI: 10.7270/Q2M9094T
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50246483 (3-ethyl-5-(5-(4-ethylpiperazin-1-ylsulfonyl)-2-pro...) Show SMILES CCCOc1ncc(cc1-c1nc2c(CC)n(Cc3ccccn3)nc2c(=O)[nH]1)S(=O)(=O)N1CCN(CC)CC1 Show InChI InChI=1S/C27H34N8O4S/c1-4-15-39-27-21(16-20(17-29-27)40(37,38)34-13-11-33(6-3)12-14-34)25-30-23-22(5-2)35(32-24(23)26(36)31-25)18-19-9-7-8-10-28-19/h7-10,16-17H,4-6,11-15,18H2,1-3H3,(H,30,31,36)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of human PDE5 isolated from corpus cavernosum after 30 to 60 mins by scintillation counting method				Bioorg Med Chem 20: 498-509 (2011) Article DOI: 10.1016/j.bmc.2011.10.022 BindingDB Entry DOI: 10.7270/Q2M9094T
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50359770 (CHEMBL1928262) Show SMILES CCOc1ncc(cc1-c1nc2c(CC)n(CCOC)nc2c(=O)[nH]1)S(=O)(=O)N1CCN(CC)CC1 Show InChI InChI=1S/C23H33N7O5S/c1-5-18-19-20(27-30(18)12-13-34-4)22(31)26-21(25-19)17-14-16(15-24-23(17)35-7-3)36(32,33)29-10-8-28(6-2)9-11-29/h14-15H,5-13H2,1-4H3,(H,25,26,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of human PDE5 isolated from corpus cavernosum after 30 to 60 mins by scintillation counting method				Bioorg Med Chem 20: 498-509 (2011) Article DOI: 10.1016/j.bmc.2011.10.022 BindingDB Entry DOI: 10.7270/Q2M9094T
					More data for this Ligand-Target Pair
Pyroglutamylated RF-amide peptide receptor (Homo sapiens (Human))	BDBM50347818 (CHEMBL1802413 | P518) Show SMILES [#6]-[#6](-[#6])-[#6]-[#6@H](-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#7])=O)-[#7]-[#6](=O)-[#6]-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#6])-[#6])-[#7]-[#6](=O)-[#6@@H]-1-[#6]-[#6]-[#6]-[#7]-1-[#6](=O)-[#6]-[#7]-[#6](=O)-[#6@H](-[#6]-[#8])-[#7]-[#6](=O)-[#6@@H](-[#7])-[#6@@H](-[#6])-[#8])-[#6](=O)-[#7]-[#6@@H](-[#6])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6](-[#8])=O)-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6](-[#8])=O)-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6](-[#6])-[#6])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6](-[#7])=O)-[#6](=O)-[#7]-[#6]-[#6](=O)-[#7]-[#6@@H](-[#6]-c1ccc(-[#8])cc1)-[#6](=O)-[#7]-[#6@@H](-[#6]-[#8])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]-[#6]-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]-[#6]-[#7])-[#6](=O)-[#7]-[#6]-[#6](=O)-[#7]-[#6]-[#6](=O)-[#7]-[#6@@H](-[#6]-c1ccccc1)-[#6](=O)-[#7]-[#6@@H](-[#6]-[#8])-[#6](=O)-[#7]-[#6@@H](-[#6]-c1ccccc1)-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6]-c1ccccc1)-[#6](-[#7])=O |r| Show InChI InChI=1S/C127H195N37O37/c1-66(2)49-83(160-124(200)94-35-24-48-164(94)101(176)62-144-110(186)91(63-165)163-125(201)104(132)70(8)168)108(184)142-61-100(175)148-90(57-96(131)171)121(197)157-84(50-67(3)4)116(192)145-69(7)106(182)149-80(40-42-102(177)178)114(190)154-81(41-43-103(179)180)115(191)156-85(51-68(5)6)117(193)159-89(56-95(130)170)109(185)143-60-99(174)147-87(55-74-36-38-75(169)39-37-74)119(195)161-92(64-166)122(198)153-78(33-22-46-138-126(134)135)112(188)151-77(32-19-21-45-129)111(187)150-76(31-18-20-44-128)107(183)141-58-97(172)140-59-98(173)146-86(53-72-27-14-10-15-28-72)118(194)162-93(65-167)123(199)158-88(54-73-29-16-11-17-30-73)120(196)152-79(34-23-47-139-127(136)137)113(189)155-82(105(133)181)52-71-25-12-9-13-26-71/h9-17,25-30,36-39,66-70,76-94,104,165-169H,18-24,31-35,40-65,128-129,132H2,1-8H3,(H2,130,170)(H2,131,171)(H2,133,181)(H,140,172)(H,141,183)(H,142,184)(H,143,185)(H,144,186)(H,145,192)(H,146,173)(H,147,174)(H,148,175)(H,149,182)(H,150,187)(H,151,188)(H,152,196)(H,153,198)(H,154,190)(H,155,189)(H,156,191)(H,157,197)(H,158,199)(H,159,193)(H,160,200)(H,161,195)(H,162,194)(H,163,201)(H,177,178)(H,179,180)(H4,134,135,138)(H4,136,137,139)/t69-,70+,76-,77-,78-,79-,80-,81-,82-,83-,84-,85-,86-,87-,88-,89-,90-,91-,92-,93-,94-,104-/m0/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
INSERM Curated by ChEMBL					Assay Description Displacement of [125I]26RFa from human GPR103 expressed in HEK293 cells incubated for 1 h by gamma counter based method				J Med Chem 55: 7516-24 (2012) Article DOI: 10.1021/jm300507d BindingDB Entry DOI: 10.7270/Q2K35VSG
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50359780 (CHEMBL1928272) Show SMILES CCN1CCN(CC1)S(=O)(=O)c1cnc(OCCOC)c(c1)-c1nc2c(CC)n(CCN3CCOCC3)nc2c(=O)[nH]1 Show InChI InChI=1S/C27H40N8O6S/c1-4-22-23-24(31-35(22)11-8-33-12-14-40-15-13-33)26(36)30-25(29-23)21-18-20(19-28-27(21)41-17-16-39-3)42(37,38)34-9-6-32(5-2)7-10-34/h18-19H,4-17H2,1-3H3,(H,29,30,36)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of human PDE5 isolated from corpus cavernosum after 30 to 60 mins by scintillation counting method				Bioorg Med Chem 20: 498-509 (2011) Article DOI: 10.1016/j.bmc.2011.10.022 BindingDB Entry DOI: 10.7270/Q2M9094T
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50359787 (CHEMBL1928250) Show SMILES CCN1CCN(CC1)S(=O)(=O)c1cnc(OCCOC)c(c1)-c1nc2c(CC)n(nc2c(=O)[nH]1)C(C)C Show InChI InChI=1S/C24H35N7O5S/c1-6-19-20-21(28-31(19)16(3)4)23(32)27-22(26-20)18-14-17(15-25-24(18)36-13-12-35-5)37(33,34)30-10-8-29(7-2)9-11-30/h14-16H,6-13H2,1-5H3,(H,26,27,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of human PDE5 isolated from corpus cavernosum after 30 to 60 mins by scintillation counting method				Bioorg Med Chem 20: 498-509 (2011) Article DOI: 10.1016/j.bmc.2011.10.022 BindingDB Entry DOI: 10.7270/Q2M9094T
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50359769 (CHEMBL1928261) Show SMILES CCN1CCN(CC1)S(=O)(=O)c1cnc(OCCOC)c(c1)-c1nc2c(CC)n(CCOC)nc2c(=O)[nH]1 Show InChI InChI=1S/C24H35N7O6S/c1-5-19-20-21(28-31(19)11-12-35-3)23(32)27-22(26-20)18-15-17(16-25-24(18)37-14-13-36-4)38(33,34)30-9-7-29(6-2)8-10-30/h15-16H,5-14H2,1-4H3,(H,26,27,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of human PDE5 isolated from corpus cavernosum after 30 to 60 mins by scintillation counting method				Bioorg Med Chem 20: 498-509 (2011) Article DOI: 10.1016/j.bmc.2011.10.022 BindingDB Entry DOI: 10.7270/Q2M9094T
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50359791 (CHEMBL1928254) Show SMILES CCN1CCN(CC1)S(=O)(=O)c1cnc(OCCOC)c(c1)-c1nc2c(CC)n(nc2c(=O)[nH]1)C1CCOCC1 Show InChI InChI=1S/C26H37N7O6S/c1-4-21-22-23(30-33(21)18-6-12-38-13-7-18)25(34)29-24(28-22)20-16-19(17-27-26(20)39-15-14-37-3)40(35,36)32-10-8-31(5-2)9-11-32/h16-18H,4-15H2,1-3H3,(H,28,29,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.70	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of human PDE5 isolated from corpus cavernosum after 30 to 60 mins by scintillation counting method				Bioorg Med Chem 20: 498-509 (2011) Article DOI: 10.1016/j.bmc.2011.10.022 BindingDB Entry DOI: 10.7270/Q2M9094T
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50359786 (CHEMBL1928249) Show SMILES CCCn1nc2c(nc([nH]c2=O)-c2cc(cnc2OCCOC)S(=O)(=O)N2CCN(CC)CC2)c1CC Show InChI InChI=1S/C24H35N7O5S/c1-5-8-31-19(6-2)20-21(28-31)23(32)27-22(26-20)18-15-17(16-25-24(18)36-14-13-35-4)37(33,34)30-11-9-29(7-3)10-12-30/h15-16H,5-14H2,1-4H3,(H,26,27,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.80	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of human PDE5 isolated from corpus cavernosum after 30 to 60 mins by scintillation counting method				Bioorg Med Chem 20: 498-509 (2011) Article DOI: 10.1016/j.bmc.2011.10.022 BindingDB Entry DOI: 10.7270/Q2M9094T
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50359788 (CHEMBL1928251) Show SMILES CCN1CCN(CC1)S(=O)(=O)c1cnc(OCCOC)c(c1)-c1nc2c(CC)n(nc2c(=O)[nH]1)C1CCC1 Show InChI InChI=1S/C25H35N7O5S/c1-4-20-21-22(29-32(20)17-7-6-8-17)24(33)28-23(27-21)19-15-18(16-26-25(19)37-14-13-36-3)38(34,35)31-11-9-30(5-2)10-12-31/h15-17H,4-14H2,1-3H3,(H,27,28,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.80	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of human PDE5 isolated from corpus cavernosum after 30 to 60 mins by scintillation counting method				Bioorg Med Chem 20: 498-509 (2011) Article DOI: 10.1016/j.bmc.2011.10.022 BindingDB Entry DOI: 10.7270/Q2M9094T
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50359772 (CHEMBL1928264) Show SMILES CCN1CCN(CC1)S(=O)(=O)c1cnc(OCC(C)C)c(c1)-c1nc2c(CC)n(CCCN(C)C)nc2c(=O)[nH]1 Show InChI InChI=1S/C27H42N8O4S/c1-7-22-23-24(31-35(22)11-9-10-32(5)6)26(36)30-25(29-23)21-16-20(17-28-27(21)39-18-19(3)4)40(37,38)34-14-12-33(8-2)13-15-34/h16-17,19H,7-15,18H2,1-6H3,(H,29,30,36)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.40	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of human PDE5 isolated from corpus cavernosum after 30 to 60 mins by scintillation counting method				Bioorg Med Chem 20: 498-509 (2011) Article DOI: 10.1016/j.bmc.2011.10.022 BindingDB Entry DOI: 10.7270/Q2M9094T
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50359782 (CHEMBL1928274) Show SMILES CCCOc1ncc(cc1-c1nc2c3CCCCn3nc2c(=O)[nH]1)S(=O)(=O)N1CCN(CC)CC1 Show InChI InChI=1S/C23H31N7O4S/c1-3-13-34-23-17(14-16(15-24-23)35(32,33)29-11-9-28(4-2)10-12-29)21-25-19-18-7-5-6-8-30(18)27-20(19)22(31)26-21/h14-15H,3-13H2,1-2H3,(H,25,26,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.5	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of human PDE5 isolated from corpus cavernosum after 30 to 60 mins by scintillation counting method				Bioorg Med Chem 20: 498-509 (2011) Article DOI: 10.1016/j.bmc.2011.10.022 BindingDB Entry DOI: 10.7270/Q2M9094T
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50359785 (CHEMBL1928277) Show SMILES CCN1CCN(CC1)S(=O)(=O)c1cnc(OCCOC)c(c1)-c1nc2c3C(C)CCCn3nc2c(=O)[nH]1 Show InChI InChI=1S/C24H33N7O5S/c1-4-29-8-10-30(11-9-29)37(33,34)17-14-18(24(25-15-17)36-13-12-35-3)22-26-19-20(23(32)27-22)28-31-7-5-6-16(2)21(19)31/h14-16H,4-13H2,1-3H3,(H,26,27,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.76	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of human PDE5 isolated from corpus cavernosum after 30 to 60 mins by scintillation counting method				Bioorg Med Chem 20: 498-509 (2011) Article DOI: 10.1016/j.bmc.2011.10.022 BindingDB Entry DOI: 10.7270/Q2M9094T
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50359793 (CHEMBL1928256) Show SMILES CCc1n(CC(C)C)nc2c1nc([nH]c2=O)-c1cc(cnc1OCCOC)S(=O)(=O)N1CCN(C)CC1 Show InChI InChI=1S/C24H35N7O5S/c1-6-19-20-21(28-31(19)15-16(2)3)23(32)27-22(26-20)18-13-17(14-25-24(18)36-12-11-35-5)37(33,34)30-9-7-29(4)8-10-30/h13-14,16H,6-12,15H2,1-5H3,(H,26,27,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.90	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of human PDE5 isolated from corpus cavernosum after 30 to 60 mins by scintillation counting method				Bioorg Med Chem 20: 498-509 (2011) Article DOI: 10.1016/j.bmc.2011.10.022 BindingDB Entry DOI: 10.7270/Q2M9094T
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM14390 (5-[2-ethoxy-5-(4-methyl-1-piperazinylsulfonyl)phen...) Show SMILES CCCc1nn(C)c2c1nc([nH]c2=O)-c1cc(ccc1OCC)S(=O)(=O)N1CCN(C)CC1 Show InChI InChI=1S/C22H30N6O4S/c1-5-7-17-19-20(27(4)25-17)22(29)24-21(23-19)16-14-15(8-9-18(16)32-6-2)33(30,31)28-12-10-26(3)11-13-28/h8-9,14H,5-7,10-13H2,1-4H3,(H,23,24,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	MMDB PDB Article PubMed	n/a	n/a	3.5	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of human PDE5 isolated from corpus cavernosum after 30 to 60 mins by scintillation counting method				Bioorg Med Chem 20: 498-509 (2011) Article DOI: 10.1016/j.bmc.2011.10.022 BindingDB Entry DOI: 10.7270/Q2M9094T
					More data for this Ligand-Target Pair				3D Structure (crystal)
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50359784 (CHEMBL1928276) Show SMILES CCOc1ncc(cc1-c1nc2c3C(C)CCCn3nc2c(=O)[nH]1)S(=O)(=O)N1CCN(CC)CC1 Show InChI InChI=1S/C23H31N7O4S/c1-4-28-9-11-29(12-10-28)35(32,33)16-13-17(23(24-14-16)34-5-2)21-25-18-19(22(31)26-21)27-30-8-6-7-15(3)20(18)30/h13-15H,4-12H2,1-3H3,(H,25,26,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.70	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of human PDE5 isolated from corpus cavernosum after 30 to 60 mins by scintillation counting method				Bioorg Med Chem 20: 498-509 (2011) Article DOI: 10.1016/j.bmc.2011.10.022 BindingDB Entry DOI: 10.7270/Q2M9094T
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50359792 (CHEMBL1928255) Show SMILES CCCn1nc2c(nc([nH]c2=O)-c2cc(cnc2OCCOC)S(=O)(=O)N2CCN(C)CC2)c1CC Show InChI InChI=1S/C23H33N7O5S/c1-5-7-30-18(6-2)19-20(27-30)22(31)26-21(25-19)17-14-16(15-24-23(17)35-13-12-34-4)36(32,33)29-10-8-28(3)9-11-29/h14-15H,5-13H2,1-4H3,(H,25,26,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.40	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of human PDE5 isolated from corpus cavernosum after 30 to 60 mins by scintillation counting method				Bioorg Med Chem 20: 498-509 (2011) Article DOI: 10.1016/j.bmc.2011.10.022 BindingDB Entry DOI: 10.7270/Q2M9094T
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50359776 (CHEMBL1928268) Show SMILES CCOc1ncc(cc1C(=O)Nc1c(CC)n(nc1C(N)=O)C1CN(C)C1)S(=O)(=O)N1CCN(CC)CC1 Show InChI InChI=1S/C24H36N8O5S/c1-5-19-20(21(22(25)33)28-32(19)16-14-29(4)15-16)27-23(34)18-12-17(13-26-24(18)37-7-3)38(35,36)31-10-8-30(6-2)9-11-31/h12-13,16H,5-11,14-15H2,1-4H3,(H2,25,33)(H,27,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	8.20	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of human PDE5 isolated from corpus cavernosum after 30 to 60 mins by scintillation counting method				Bioorg Med Chem 20: 498-509 (2011) Article DOI: 10.1016/j.bmc.2011.10.022 BindingDB Entry DOI: 10.7270/Q2M9094T
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50359783 (CHEMBL1928275) Show SMILES CCN1CCN(CC1)S(=O)(=O)c1cnc(OCCOC)c(c1)-c1nc2c3CCCCn3nc2c(=O)[nH]1 Show InChI InChI=1S/C23H31N7O5S/c1-3-28-8-10-29(11-9-28)36(32,33)16-14-17(23(24-15-16)35-13-12-34-2)21-25-19-18-6-4-5-7-30(18)27-20(19)22(31)26-21/h14-15H,3-13H2,1-2H3,(H,25,26,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	8.5	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of human PDE5 isolated from corpus cavernosum after 30 to 60 mins by scintillation counting method				Bioorg Med Chem 20: 498-509 (2011) Article DOI: 10.1016/j.bmc.2011.10.022 BindingDB Entry DOI: 10.7270/Q2M9094T
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50359781 (CHEMBL1928273) Show SMILES CCOc1ncc(cc1-c1nc2c3CCCCn3nc2c(=O)[nH]1)S(=O)(=O)N1CCN(CC)CC1 Show InChI InChI=1S/C22H29N7O4S/c1-3-27-9-11-28(12-10-27)34(31,32)15-13-16(22(23-14-15)33-4-2)20-24-18-17-7-5-6-8-29(17)26-19(18)21(30)25-20/h13-14H,3-12H2,1-2H3,(H,24,25,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of human PDE5 isolated from corpus cavernosum after 30 to 60 mins by scintillation counting method				Bioorg Med Chem 20: 498-509 (2011) Article DOI: 10.1016/j.bmc.2011.10.022 BindingDB Entry DOI: 10.7270/Q2M9094T
					More data for this Ligand-Target Pair
cGMP-specific 3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50359775 (CHEMBL1928267) Show SMILES CCOc1ncc(cc1C(=O)Nc1c(CC)n(nc1C(N)=O)C1CNC1)S(=O)(=O)N1CCN(CC)CC1 Show InChI InChI=1S/C23H34N8O5S/c1-4-18-19(20(21(24)32)28-31(18)15-12-25-13-15)27-22(33)17-11-16(14-26-23(17)36-6-3)37(34,35)30-9-7-29(5-2)8-10-30/h11,14-15,25H,4-10,12-13H2,1-3H3,(H2,24,32)(H,27,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of human PDE5 isolated from corpus cavernosum after 30 to 60 mins by scintillation counting method				Bioorg Med Chem 20: 498-509 (2011) Article DOI: 10.1016/j.bmc.2011.10.022 BindingDB Entry DOI: 10.7270/Q2M9094T
					More data for this Ligand-Target Pair
Calpain-1 catalytic subunit (Homo sapiens (Human))	BDBM50069792 ((2S)-2-[(2S)-2-acetamido-4-methylpentanamido]-N-[(...) Show SMILES CCCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(C)=O)C=O |r| Show InChI InChI=1S/C20H37N3O4/c1-7-8-9-16(12-24)22-19(26)18(11-14(4)5)23-20(27)17(10-13(2)3)21-15(6)25/h12-14,16-18H,7-11H2,1-6H3,(H,21,25)(H,22,26)(H,23,27)/t16-,17-,18-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Université Rennes 1 Curated by ChEMBL					Assay Description Inhibitory concentration against Calpain I activity				J Med Chem 48: 330-4 (2005) Article DOI: 10.1021/jm049455f BindingDB Entry DOI: 10.7270/Q2H994PD
					More data for this Ligand-Target Pair
Pyroglutamylated RF-amide peptide receptor (Homo sapiens (Human))	BDBM50396422 (CHEMBL2170403) Show SMILES [#7]\[#6](-[#7])=[#7]/[#6]-[#6]-[#6]-[#6@H](-[#7]-[#6](=O)-[#6@H](-[#6]-c1ccccc1)-[#7]-[#6](=O)-[#6]-[#7](-[#6]-[#6](-[#8])-[#6]-[#8])-[#7]-[#6](=O)-[#6@H](-[#6]-c1ccccc1)-[#7]-[#6](=O)-[#6]-[#7]-1-[#6]-[#6]-[#7]-[#6]-[#6]-1)-[#6](=O)-[#7]-[#6@@H](-[#6]-c1ccccc1)-[#6](-[#7])=O |r| Show InChI InChI=1S/C44H62N12O8/c45-40(61)35(23-30-11-4-1-5-12-30)53-41(62)34(17-10-18-49-44(46)47)52-42(63)36(24-31-13-6-2-7-14-31)50-39(60)28-56(26-33(58)29-57)54-43(64)37(25-32-15-8-3-9-16-32)51-38(59)27-55-21-19-48-20-22-55/h1-9,11-16,33-37,48,57-58H,10,17-29H2,(H2,45,61)(H,50,60)(H,51,59)(H,52,63)(H,53,62)(H,54,64)(H4,46,47,49)/t33?,34-,35-,36-,37-/m0/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.99E+3	n/a	n/a	n/a	n/a	n/a	n/a
INSERM Curated by ChEMBL					Assay Description Displacement of [125I]26RFa from human GPR103 expressed in HEK293 cells incubated for 1 h by gamma counter based method				J Med Chem 55: 7516-24 (2012) Article DOI: 10.1021/jm300507d BindingDB Entry DOI: 10.7270/Q2K35VSG
					More data for this Ligand-Target Pair
Pyroglutamylated RF-amide peptide receptor (Homo sapiens (Human))	BDBM50396420 (CHEMBL2170390) Show SMILES [#7]-[#6]-[#6](=O)-[#7]-[#7]-[#6]-[#6](=O)-[#7]-[#6@@H](-[#6]-c1ccccc1)-[#6](=O)-[#7]-[#6@@H](-[#6]-[#8])-[#6](=O)-[#7]-[#6@@H](-[#6]-c1ccccc1)-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6]-c1ccccc1)-[#6](-[#7])=O |r| Show InChI InChI=1S/C40H54N12O8/c41-22-33(54)52-46-23-34(55)47-30(20-26-13-6-2-7-14-26)37(58)51-32(24-53)39(60)50-31(21-27-15-8-3-9-16-27)38(59)48-28(17-10-18-45-40(43)44)36(57)49-29(35(42)56)19-25-11-4-1-5-12-25/h1-9,11-16,28-32,46,53H,10,17-24,41H2,(H2,42,56)(H,47,55)(H,48,59)(H,49,57)(H,50,60)(H,51,58)(H,52,54)(H4,43,44,45)/t28-,29-,30-,31-,32-/m0/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.99E+3	n/a	n/a	n/a	n/a	n/a	n/a
INSERM Curated by ChEMBL					Assay Description Displacement of [125I]26RFa from human GPR103 expressed in HEK293 cells incubated for 1 h by gamma counter based method				J Med Chem 55: 7516-24 (2012) Article DOI: 10.1021/jm300507d BindingDB Entry DOI: 10.7270/Q2K35VSG
					More data for this Ligand-Target Pair
Pyroglutamylated RF-amide peptide receptor (Homo sapiens (Human))	BDBM50347830 (CHEMBL1802425) Show SMILES [#7]-[#6]-[#6](=O)-[#7]-[#6]-[#6](=O)-[#7]-[#6@@H](-[#6]-c1ccccc1)-[#6](=O)-[#7]-[#6@@H](-[#6]-[#8])-[#6](=O)-[#7]-[#6@@H](-[#6]-c1ccccc1)-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6]-c1ccccc1)-[#6](-[#7])=O |r| Show InChI InChI=1S/C40H53N11O8/c41-22-33(53)46-23-34(54)47-30(20-26-13-6-2-7-14-26)37(57)51-32(24-52)39(59)50-31(21-27-15-8-3-9-16-27)38(58)48-28(17-10-18-45-40(43)44)36(56)49-29(35(42)55)19-25-11-4-1-5-12-25/h1-9,11-16,28-32,52H,10,17-24,41H2,(H2,42,55)(H,46,53)(H,47,54)(H,48,58)(H,49,56)(H,50,59)(H,51,57)(H4,43,44,45)/t28-,29-,30-,31-,32-/m0/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.73E+3	n/a	n/a	n/a	n/a	n/a	n/a
INSERM Curated by ChEMBL					Assay Description Displacement of [125I]26RFa from human GPR103 expressed in HEK293 cells incubated for 1 h by gamma counter based method				J Med Chem 55: 7516-24 (2012) Article DOI: 10.1021/jm300507d BindingDB Entry DOI: 10.7270/Q2K35VSG
					More data for this Ligand-Target Pair
Pyroglutamylated RF-amide peptide receptor (Homo sapiens (Human))	BDBM50396417 (CHEMBL2170395) Show SMILES [#7]-[#6]-[#6](=O)-[#7]-[#6]-[#6](=O)-[#7]-[#6@@H](-[#6]-c1ccccc1)-[#6](=O)-[#7]-[#6@@H](-[#6]-[#8])-[#6](=O)-[#7]-[#6@@H](-[#6]-c1ccccc1)-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#6](=O)-[#7]-[#7](-[#6]-[#6](-[#7])=O)-[#6]-c1ccccc1 |r| Show InChI InChI=1S/C40H54N12O8/c41-21-34(55)46-22-35(56)47-30(19-26-11-4-1-5-12-26)36(57)50-32(25-53)38(59)49-31(20-27-13-6-2-7-14-27)37(58)48-29(17-10-18-45-40(43)44)39(60)51-52(24-33(42)54)23-28-15-8-3-9-16-28/h1-9,11-16,29-32,53H,10,17-25,41H2,(H2,42,54)(H,46,55)(H,47,56)(H,48,58)(H,49,59)(H,50,57)(H,51,60)(H4,43,44,45)/t29-,30-,31-,32-/m0/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
INSERM Curated by ChEMBL					Assay Description Antagonist activity at human GPR103 expressed in CHO cells co-expressing Galpha16 assessed as inhibition of human 26RFa-induced increase in intracell...				J Med Chem 55: 7516-24 (2012) Article DOI: 10.1021/jm300507d BindingDB Entry DOI: 10.7270/Q2K35VSG
					More data for this Ligand-Target Pair
Pyroglutamylated RF-amide peptide receptor (Homo sapiens (Human))	BDBM50396418 (CHEMBL2170394) Show SMILES [#7]-[#6]-[#6](=O)-[#7]-[#6]-[#6](=O)-[#7]-[#6@@H](-[#6]-c1ccccc1)-[#6](=O)-[#7]-[#6@@H](-[#6]-[#8])-[#6](=O)-[#7]-[#6@@H](-[#6]-c1ccccc1)-[#6](=O)-[#7]-[#7](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#6]-[#6](=O)-[#7]-[#6@@H](-[#6]-c1ccccc1)-[#6](-[#7])=O |r| Show InChI InChI=1S/C40H54N12O8/c41-22-33(54)46-23-34(55)48-30(20-27-13-6-2-7-14-27)37(58)50-32(25-53)38(59)49-31(21-28-15-8-3-9-16-28)39(60)51-52(18-10-17-45-40(43)44)24-35(56)47-29(36(42)57)19-26-11-4-1-5-12-26/h1-9,11-16,29-32,53H,10,17-25,41H2,(H2,42,57)(H,46,54)(H,47,56)(H,48,55)(H,49,59)(H,50,58)(H,51,60)(H4,43,44,45)/t29-,30-,31-,32-/m0/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
INSERM Curated by ChEMBL					Assay Description Antagonist activity at human GPR103 expressed in CHO cells co-expressing Galpha16 assessed as inhibition of human 26RFa-induced increase in intracell...				J Med Chem 55: 7516-24 (2012) Article DOI: 10.1021/jm300507d BindingDB Entry DOI: 10.7270/Q2K35VSG
					More data for this Ligand-Target Pair
Pyroglutamylated RF-amide peptide receptor (Homo sapiens (Human))	BDBM50396416 (CHEMBL2170398) Show SMILES [#6]-[#6]-[#6]-[#7](-[#6]-[#6](=O)-[#7]-[#6@@H](-[#6]-c1ccccc1)-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6]-c1ccccc1)-[#6](-[#7])=O)-[#7]-[#6](=O)-[#6@H](-[#6]-c1ccccc1)-[#7]-[#6](=O)-[#6]-[#7]-[#6](=O)-[#6]-[#7] |r| Show InChI InChI=1S/C42H58N12O7/c1-2-21-54(53-41(61)34(24-30-17-10-5-11-18-30)49-36(56)26-48-35(55)25-43)27-37(57)50-33(23-29-15-8-4-9-16-29)40(60)51-31(19-12-20-47-42(45)46)39(59)52-32(38(44)58)22-28-13-6-3-7-14-28/h3-11,13-18,31-34H,2,12,19-27,43H2,1H3,(H2,44,58)(H,48,55)(H,49,56)(H,50,57)(H,51,60)(H,52,59)(H,53,61)(H4,45,46,47)/t31-,32-,33-,34-/m0/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
INSERM Curated by ChEMBL					Assay Description Antagonist activity at human GPR103 expressed in CHO cells co-expressing Galpha16 assessed as inhibition of human 26RFa-induced increase in intracell...				J Med Chem 55: 7516-24 (2012) Article DOI: 10.1021/jm300507d BindingDB Entry DOI: 10.7270/Q2K35VSG
					More data for this Ligand-Target Pair
Pyroglutamylated RF-amide peptide receptor (Homo sapiens (Human))	BDBM50396419 (CHEMBL2170393) Show SMILES [#7]-[#6]-[#6](=O)-[#7]-[#6]-[#6](=O)-[#7]-[#6@@H](-[#6]-c1ccccc1)-[#6](=O)-[#7]-[#6@@H](-[#6]-[#8])-[#6](=O)-[#7]-[#7](-[#6]-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6]-c1ccccc1)-[#6](-[#7])=O)-[#6]-c1ccccc1 |r| Show InChI InChI=1S/C40H54N12O8/c41-21-33(54)46-22-34(55)48-31(20-27-13-6-2-7-14-27)38(59)50-32(25-53)39(60)51-52(23-28-15-8-3-9-16-28)24-35(56)47-29(17-10-18-45-40(43)44)37(58)49-30(36(42)57)19-26-11-4-1-5-12-26/h1-9,11-16,29-32,53H,10,17-25,41H2,(H2,42,57)(H,46,54)(H,47,56)(H,48,55)(H,49,58)(H,50,59)(H,51,60)(H4,43,44,45)/t29-,30-,31-,32-/m0/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
INSERM Curated by ChEMBL					Assay Description Antagonist activity at human GPR103 expressed in CHO cells co-expressing Galpha16 assessed as inhibition of human 26RFa-induced increase in intracell...				J Med Chem 55: 7516-24 (2012) Article DOI: 10.1021/jm300507d BindingDB Entry DOI: 10.7270/Q2K35VSG
					More data for this Ligand-Target Pair
Cathepsin B (Homo sapiens (Human))	BDBM50159158 (CHEMBL433563 | Peptidyl boronic acid derivative) Show SMILES CC(C)CN(CC(=O)N(CC(C)C)NC(=O)OCc1ccccc1)N=Cc1ccccc1B(O)O |w:25.26| Show InChI InChI=1S/C25H35BN4O5/c1-19(2)15-29(27-14-22-12-8-9-13-23(22)26(33)34)17-24(31)30(16-20(3)4)28-25(32)35-18-21-10-6-5-7-11-21/h5-14,19-20,33-34H,15-18H2,1-4H3,(H,28,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
Université Rennes 1 Curated by ChEMBL					Assay Description In vitro inhibitory activity against Factor Xa				J Med Chem 48: 330-4 (2005) Article DOI: 10.1021/jm049455f BindingDB Entry DOI: 10.7270/Q2H994PD
					More data for this Ligand-Target Pair
Calpain-1 catalytic subunit (Homo sapiens (Human))	BDBM50159149 (CHEMBL179042 | Peptidyl boronic acid derivative) Show SMILES CC(C)CN(NC(=O)OCc1ccccc1)C(=O)CN(Cc1ccccc1)N=Cc1cccc(c1)B(O)O |w:28.30| Show InChI InChI=1S/C28H33BN4O5/c1-22(2)18-33(31-28(35)38-21-24-12-7-4-8-13-24)27(34)20-32(19-23-10-5-3-6-11-23)30-17-25-14-9-15-26(16-25)29(36)37/h3-17,22,36-37H,18-21H2,1-2H3,(H,31,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
Université Rennes 1 Curated by ChEMBL					Assay Description Inhibitory concentration against Calpain I activity				J Med Chem 48: 330-4 (2005) Article DOI: 10.1021/jm049455f BindingDB Entry DOI: 10.7270/Q2H994PD
					More data for this Ligand-Target Pair
Calpain-1 catalytic subunit (Homo sapiens (Human))	BDBM50159158 (CHEMBL433563 | Peptidyl boronic acid derivative) Show SMILES CC(C)CN(CC(=O)N(CC(C)C)NC(=O)OCc1ccccc1)N=Cc1ccccc1B(O)O |w:25.26| Show InChI InChI=1S/C25H35BN4O5/c1-19(2)15-29(27-14-22-12-8-9-13-23(22)26(33)34)17-24(31)30(16-20(3)4)28-25(32)35-18-21-10-6-5-7-11-21/h5-14,19-20,33-34H,15-18H2,1-4H3,(H,28,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
Université Rennes 1 Curated by ChEMBL					Assay Description Inhibitory concentration against Calpain I activity				J Med Chem 48: 330-4 (2005) Article DOI: 10.1021/jm049455f BindingDB Entry DOI: 10.7270/Q2H994PD
					More data for this Ligand-Target Pair
Cathepsin B (Homo sapiens (Human))	BDBM50159149 (CHEMBL179042 | Peptidyl boronic acid derivative) Show SMILES CC(C)CN(NC(=O)OCc1ccccc1)C(=O)CN(Cc1ccccc1)N=Cc1cccc(c1)B(O)O |w:28.30| Show InChI InChI=1S/C28H33BN4O5/c1-22(2)18-33(31-28(35)38-21-24-12-7-4-8-13-24)27(34)20-32(19-23-10-5-3-6-11-23)30-17-25-14-9-15-26(16-25)29(36)37/h3-17,22,36-37H,18-21H2,1-2H3,(H,31,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
Université Rennes 1 Curated by ChEMBL					Assay Description In vitro inhibitory activity against Factor Xa				J Med Chem 48: 330-4 (2005) Article DOI: 10.1021/jm049455f BindingDB Entry DOI: 10.7270/Q2H994PD
					More data for this Ligand-Target Pair
Pyroglutamylated RF-amide peptide receptor (Homo sapiens (Human))	BDBM50396426 (CHEMBL2170399) Show SMILES [#6]-[#6]-[#6]-[#6]-[#7](-[#6]-[#6](=O)-[#7]-[#6@@H](-[#6]-c1ccccc1)-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6]-c1ccccc1)-[#6](-[#7])=O)-[#7]-[#6](=O)-[#6@H](-[#6]-c1ccccc1)-[#7]-[#6](=O)-[#6]-[#7]-[#6](=O)-[#6]-[#7] |r| Show InChI InChI=1S/C43H60N12O7/c1-2-3-22-55(54-42(62)35(25-31-18-11-6-12-19-31)50-37(57)27-49-36(56)26-44)28-38(58)51-34(24-30-16-9-5-10-17-30)41(61)52-32(20-13-21-48-43(46)47)40(60)53-33(39(45)59)23-29-14-7-4-8-15-29/h4-12,14-19,32-35H,2-3,13,20-28,44H2,1H3,(H2,45,59)(H,49,56)(H,50,57)(H,51,58)(H,52,61)(H,53,60)(H,54,62)(H4,46,47,48)/t32-,33-,34-,35-/m0/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.98E+4	n/a	n/a	n/a	n/a
INSERM Curated by ChEMBL					Assay Description Agonist activity at human GPR103 expressed in CHO cells co-expressing Galpha16 assessed as increase in intracellular calcium level measured for 2 min...				J Med Chem 55: 7516-24 (2012) Article DOI: 10.1021/jm300507d BindingDB Entry DOI: 10.7270/Q2K35VSG
					More data for this Ligand-Target Pair
Pyroglutamylated RF-amide peptide receptor (Homo sapiens (Human))	BDBM50396425 (CHEMBL2170400) Show SMILES [#7]-[#6]-[#6](=O)-[#7]-[#6]-[#6](=O)-[#7]-[#6@@H](-[#6]-c1ccccc1)-[#6](=O)-[#7]-[#7](-[#6]-[#6]-1-[#6]-[#6]-[#6]-[#6]-[#6]-1)-[#6]-[#6](=O)-[#7]-[#6@@H](-[#6]-c1ccccc1)-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6]-c1ccccc1)-[#6](-[#7])=O |r| Show InChI InChI=1S/C46H64N12O7/c47-27-39(59)52-28-40(60)53-38(26-33-18-9-3-10-19-33)45(65)57-58(29-34-20-11-4-12-21-34)30-41(61)54-37(25-32-16-7-2-8-17-32)44(64)55-35(22-13-23-51-46(49)50)43(63)56-36(42(48)62)24-31-14-5-1-6-15-31/h1-3,5-10,14-19,34-38H,4,11-13,20-30,47H2,(H2,48,62)(H,52,59)(H,53,60)(H,54,61)(H,55,64)(H,56,63)(H,57,65)(H4,49,50,51)/t35-,36-,37-,38-/m0/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.37E+3	n/a	n/a	n/a	n/a
INSERM Curated by ChEMBL					Assay Description Agonist activity at human GPR103 expressed in CHO cells co-expressing Galpha16 assessed as increase in intracellular calcium level measured for 2 min...				J Med Chem 55: 7516-24 (2012) Article DOI: 10.1021/jm300507d BindingDB Entry DOI: 10.7270/Q2K35VSG
					More data for this Ligand-Target Pair
Pyroglutamylated RF-amide peptide receptor (Homo sapiens (Human))	BDBM50347818 (CHEMBL1802413 | P518) Show SMILES [#6]-[#6](-[#6])-[#6]-[#6@H](-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#7])=O)-[#7]-[#6](=O)-[#6]-[#7]-[#6](=O)-[#6@H](-[#6]-[#6](-[#6])-[#6])-[#7]-[#6](=O)-[#6@@H]-1-[#6]-[#6]-[#6]-[#7]-1-[#6](=O)-[#6]-[#7]-[#6](=O)-[#6@H](-[#6]-[#8])-[#7]-[#6](=O)-[#6@@H](-[#7])-[#6@@H](-[#6])-[#8])-[#6](=O)-[#7]-[#6@@H](-[#6])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6](-[#8])=O)-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6](-[#8])=O)-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6](-[#6])-[#6])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6](-[#7])=O)-[#6](=O)-[#7]-[#6]-[#6](=O)-[#7]-[#6@@H](-[#6]-c1ccc(-[#8])cc1)-[#6](=O)-[#7]-[#6@@H](-[#6]-[#8])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]-[#6]-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]-[#6]-[#7])-[#6](=O)-[#7]-[#6]-[#6](=O)-[#7]-[#6]-[#6](=O)-[#7]-[#6@@H](-[#6]-c1ccccc1)-[#6](=O)-[#7]-[#6@@H](-[#6]-[#8])-[#6](=O)-[#7]-[#6@@H](-[#6]-c1ccccc1)-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6]-c1ccccc1)-[#6](-[#7])=O |r| Show InChI InChI=1S/C127H195N37O37/c1-66(2)49-83(160-124(200)94-35-24-48-164(94)101(176)62-144-110(186)91(63-165)163-125(201)104(132)70(8)168)108(184)142-61-100(175)148-90(57-96(131)171)121(197)157-84(50-67(3)4)116(192)145-69(7)106(182)149-80(40-42-102(177)178)114(190)154-81(41-43-103(179)180)115(191)156-85(51-68(5)6)117(193)159-89(56-95(130)170)109(185)143-60-99(174)147-87(55-74-36-38-75(169)39-37-74)119(195)161-92(64-166)122(198)153-78(33-22-46-138-126(134)135)112(188)151-77(32-19-21-45-129)111(187)150-76(31-18-20-44-128)107(183)141-58-97(172)140-59-98(173)146-86(53-72-27-14-10-15-28-72)118(194)162-93(65-167)123(199)158-88(54-73-29-16-11-17-30-73)120(196)152-79(34-23-47-139-127(136)137)113(189)155-82(105(133)181)52-71-25-12-9-13-26-71/h9-17,25-30,36-39,66-70,76-94,104,165-169H,18-24,31-35,40-65,128-129,132H2,1-8H3,(H2,130,170)(H2,131,171)(H2,133,181)(H,140,172)(H,141,183)(H,142,184)(H,143,185)(H,144,186)(H,145,192)(H,146,173)(H,147,174)(H,148,175)(H,149,182)(H,150,187)(H,151,188)(H,152,196)(H,153,198)(H,154,190)(H,155,189)(H,156,191)(H,157,197)(H,158,199)(H,159,193)(H,160,200)(H,161,195)(H,162,194)(H,163,201)(H,177,178)(H,179,180)(H4,134,135,138)(H4,136,137,139)/t69-,70+,76-,77-,78-,79-,80-,81-,82-,83-,84-,85-,86-,87-,88-,89-,90-,91-,92-,93-,94-,104-/m0/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	10	n/a	n/a	n/a	n/a
INSERM Curated by ChEMBL					Assay Description Agonist activity at human GPR103 expressed in CHO cells co-expressing Galpha16 assessed as increase in intracellular calcium level measured for 2 min...				J Med Chem 55: 7516-24 (2012) Article DOI: 10.1021/jm300507d BindingDB Entry DOI: 10.7270/Q2K35VSG
					More data for this Ligand-Target Pair
Pyroglutamylated RF-amide peptide receptor (Homo sapiens (Human))	BDBM50347830 (CHEMBL1802425) Show SMILES [#7]-[#6]-[#6](=O)-[#7]-[#6]-[#6](=O)-[#7]-[#6@@H](-[#6]-c1ccccc1)-[#6](=O)-[#7]-[#6@@H](-[#6]-[#8])-[#6](=O)-[#7]-[#6@@H](-[#6]-c1ccccc1)-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6]-c1ccccc1)-[#6](-[#7])=O |r| Show InChI InChI=1S/C40H53N11O8/c41-22-33(53)46-23-34(54)47-30(20-26-13-6-2-7-14-26)37(57)51-32(24-52)39(59)50-31(21-27-15-8-3-9-16-27)38(58)48-28(17-10-18-45-40(43)44)36(56)49-29(35(42)55)19-25-11-4-1-5-12-25/h1-9,11-16,28-32,52H,10,17-24,41H2,(H2,42,55)(H,46,53)(H,47,54)(H,48,58)(H,49,56)(H,50,59)(H,51,57)(H4,43,44,45)/t28-,29-,30-,31-,32-/m0/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	739	n/a	n/a	n/a	n/a
INSERM Curated by ChEMBL					Assay Description Agonist activity at human GPR103 expressed in CHO cells co-expressing Galpha16 assessed as increase in intracellular calcium level measured for 2 min...				J Med Chem 55: 7516-24 (2012) Article DOI: 10.1021/jm300507d BindingDB Entry DOI: 10.7270/Q2K35VSG
					More data for this Ligand-Target Pair
Pyroglutamylated RF-amide peptide receptor (Homo sapiens (Human))	BDBM50396431 (CHEMBL2170389) Show SMILES [#7]-[#7]-[#6]-[#6](=O)-[#7]-[#6]-[#6](=O)-[#7]-[#6@@H](-[#6]-c1ccccc1)-[#6](=O)-[#7]-[#6@@H](-[#6]-[#8])-[#6](=O)-[#7]-[#6@@H](-[#6]-c1ccccc1)-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6]-c1ccccc1)-[#6](-[#7])=O |r| Show InChI InChI=1S/C40H54N12O8/c41-35(56)29(19-25-11-4-1-5-12-25)50-36(57)28(17-10-18-45-40(42)43)49-38(59)31(21-27-15-8-3-9-16-27)51-39(60)32(24-53)52-37(58)30(20-26-13-6-2-7-14-26)48-34(55)22-46-33(54)23-47-44/h1-9,11-16,28-32,47,53H,10,17-24,44H2,(H2,41,56)(H,46,54)(H,48,55)(H,49,59)(H,50,57)(H,51,60)(H,52,58)(H4,42,43,45)/t28-,29-,30-,31-,32-/m0/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	429	n/a	n/a	n/a	n/a
INSERM Curated by ChEMBL					Assay Description Agonist activity at human GPR103 expressed in CHO cells co-expressing Galpha16 assessed as increase in intracellular calcium level measured for 2 min...				J Med Chem 55: 7516-24 (2012) Article DOI: 10.1021/jm300507d BindingDB Entry DOI: 10.7270/Q2K35VSG
					More data for this Ligand-Target Pair
Pyroglutamylated RF-amide peptide receptor (Homo sapiens (Human))	BDBM50396430 (CHEMBL2170391) Show SMILES [#7]-[#6]-[#6](=O)-[#7]-[#6]-[#6](=O)-[#7]-[#7](-[#6]-[#6](=O)-[#7]-[#6@@H](-[#6]-[#8])-[#6](=O)-[#7]-[#6@@H](-[#6]-c1ccccc1)-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6]-c1ccccc1)-[#6](-[#7])=O)-[#6]-c1ccccc1 |r| Show InChI InChI=1S/C40H54N12O8/c41-21-33(54)46-22-34(55)51-52(23-28-15-8-3-9-16-28)24-35(56)47-32(25-53)39(60)50-31(20-27-13-6-2-7-14-27)38(59)48-29(17-10-18-45-40(43)44)37(58)49-30(36(42)57)19-26-11-4-1-5-12-26/h1-9,11-16,29-32,53H,10,17-25,41H2,(H2,42,57)(H,46,54)(H,47,56)(H,48,59)(H,49,58)(H,50,60)(H,51,55)(H4,43,44,45)/t29-,30-,31-,32-/m0/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.34E+3	n/a	n/a	n/a	n/a
INSERM Curated by ChEMBL					Assay Description Agonist activity at human GPR103 expressed in CHO cells co-expressing Galpha16 assessed as increase in intracellular calcium level measured for 2 min...				J Med Chem 55: 7516-24 (2012) Article DOI: 10.1021/jm300507d BindingDB Entry DOI: 10.7270/Q2K35VSG
					More data for this Ligand-Target Pair
Pyroglutamylated RF-amide peptide receptor (Homo sapiens (Human))	BDBM50396429 (CHEMBL2170392) Show SMILES [#7]-[#6]-[#6](=O)-[#7]-[#6]-[#6](=O)-[#7]-[#6@@H](-[#6]-c1ccccc1)-[#6](=O)-[#7]-[#7](-[#6]-[#6]-[#8])-[#6]-[#6](=O)-[#7]-[#6@@H](-[#6]-c1ccccc1)-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](/[#7])-[#7])-[#6](=O)-[#7]-[#6@@H](-[#6]-c1ccccc1)-[#6](-[#7])=O |r| Show InChI InChI=1S/C41H56N12O8/c42-24-34(55)47-25-35(56)48-33(23-29-15-8-3-9-16-29)40(61)52-53(19-20-54)26-36(57)49-32(22-28-13-6-2-7-14-28)39(60)50-30(17-10-18-46-41(44)45)38(59)51-31(37(43)58)21-27-11-4-1-5-12-27/h1-9,11-16,30-33,54H,10,17-26,42H2,(H2,43,58)(H,47,55)(H,48,56)(H,49,57)(H,50,60)(H,51,59)(H,52,61)(H4,44,45,46)/t30-,31-,32-,33-/m0/s1	UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.09E+3	n/a	n/a	n/a	n/a
INSERM Curated by ChEMBL					Assay Description Agonist activity at human GPR103 expressed in CHO cells co-expressing Galpha16 assessed as increase in intracellular calcium level measured for 2 min...				J Med Chem 55: 7516-24 (2012) Article DOI: 10.1021/jm300507d BindingDB Entry DOI: 10.7270/Q2K35VSG
					More data for this Ligand-Target Pair

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